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Search of human proteins with 91823274
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|91823274 autotaxin isoform 1 preproprotein [Homo sapiens]
(915 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|91823274 autotaxin isoform 1 preproprotein [Homo sapiens] 1939 0.0
gi|91823602 autotaxin isoform 2 preproprotein [Homo sapiens] 1808 0.0
gi|195947389 autotaxin isoform 3 preproprotein [Homo sapiens] 1795 0.0
gi|111160296 ectonucleotide pyrophosphatase/phosphodiesterase 3 ... 771 0.0
gi|170650661 ectonucleotide pyrophosphatase/phosphodiesterase 1 ... 738 0.0
gi|7662358 ectonucleotide pyrophosphatase/phosphodiesterase 4 (p... 172 1e-42
gi|11034849 ectonucleotide pyrophosphatase/phosphodiesterase 5 (... 160 7e-39
gi|23503267 ectonucleotide pyrophosphatase/phosphodiesterase 6 [... 154 4e-37
gi|45545421 ectonucleotide pyrophosphatase/phosphodiesterase 7 [... 154 5e-37
gi|239755573 PREDICTED: similar to ectonucleotide pyrophosphatas... 60 7e-09
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 54 9e-07
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 54 9e-07
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 49 2e-05
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 49 2e-05
gi|88853069 vitronectin precursor [Homo sapiens] 42 0.003
gi|5174623 placental protein 11 precursor [Homo sapiens] 41 0.006
gi|4557733 latent transforming growth factor beta binding protei... 40 0.013
gi|169217819 PREDICTED: similar to hCG1793095 [Homo sapiens] 38 0.049
gi|239756564 PREDICTED: similar to hCG1793095 [Homo sapiens] 38 0.049
gi|187608744 zinc finger protein 9 isoform 5 [Homo sapiens] 38 0.049
gi|123702038 keratin associated protein 5-9 [Homo sapiens] 38 0.049
gi|209969800 RPE-spondin [Homo sapiens] 36 0.14
gi|187608732 zinc finger protein 9 isoform 2 [Homo sapiens] 35 0.24
gi|98985828 ADAM metallopeptidase domain 28 isoform 1 preproprot... 35 0.24
gi|66346695 fibrillin 2 precursor [Homo sapiens] 35 0.32
gi|23308689 RNA pseudouridylate synthase domain containing 2 [Ho... 35 0.32
gi|190358524 follistatin-like 5 isoform c [Homo sapiens] 35 0.42
gi|190358522 follistatin-like 5 isoform b [Homo sapiens] 35 0.42
gi|190358520 follistatin-like 5 isoform a [Homo sapiens] 35 0.42
gi|93102379 low density lipoprotein-related protein 1B precursor... 33 0.93
>gi|91823274 autotaxin isoform 1 preproprotein [Homo sapiens]
Length = 915
Score = 1939 bits (5024), Expect = 0.0
Identities = 915/915 (100%), Positives = 915/915 (100%)
Query: 1 MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCK 60
MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCK
Sbjct: 1 MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCK 60
Query: 61 GRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHC 120
GRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHC
Sbjct: 61 GRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHC 120
Query: 121 SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK 180
SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK
Sbjct: 121 SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK 180
Query: 181 KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA 240
KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA
Sbjct: 181 KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA 240
Query: 241 TFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHER 300
TFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHER
Sbjct: 241 TFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHER 300
Query: 301 PSVYAFYSEQPDFSGHKYGPFGPEESSYGSPFTPAKRPKRKVAPKRRQERPVAPPKKRRR 360
PSVYAFYSEQPDFSGHKYGPFGPEESSYGSPFTPAKRPKRKVAPKRRQERPVAPPKKRRR
Sbjct: 301 PSVYAFYSEQPDFSGHKYGPFGPEESSYGSPFTPAKRPKRKVAPKRRQERPVAPPKKRRR 360
Query: 361 KIHRMDHYAAETRQDKMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCD 420
KIHRMDHYAAETRQDKMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCD
Sbjct: 361 KIHRMDHYAAETRQDKMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCD 420
Query: 421 RTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQH 480
RTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQH
Sbjct: 421 RTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQH 480
Query: 481 LPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVF 540
LPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVF
Sbjct: 481 LPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVF 540
Query: 541 VGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEV 600
VGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEV
Sbjct: 541 VGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEV 600
Query: 601 TRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTEERHLLYGRPAVLYRT 660
TRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTEERHLLYGRPAVLYRT
Sbjct: 601 TRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTEERHLLYGRPAVLYRT 660
Query: 661 RYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCL 720
RYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCL
Sbjct: 661 RYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCL 720
Query: 721 AYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASER 780
AYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASER
Sbjct: 721 AYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASER 780
Query: 781 NGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGP 840
NGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGP
Sbjct: 781 NGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGP 840
Query: 841 LSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYPE 900
LSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYPE
Sbjct: 841 LSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYPE 900
Query: 901 ILTLKTYLHTYESEI 915
ILTLKTYLHTYESEI
Sbjct: 901 ILTLKTYLHTYESEI 915
>gi|91823602 autotaxin isoform 2 preproprotein [Homo sapiens]
Length = 863
Score = 1808 bits (4684), Expect = 0.0
Identities = 863/915 (94%), Positives = 863/915 (94%), Gaps = 52/915 (5%)
Query: 1 MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCK 60
MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCK
Sbjct: 1 MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCK 60
Query: 61 GRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHC 120
GRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHC
Sbjct: 61 GRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHC 120
Query: 121 SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK 180
SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK
Sbjct: 121 SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK 180
Query: 181 KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA 240
KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA
Sbjct: 181 KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA 240
Query: 241 TFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHER 300
TFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHER
Sbjct: 241 TFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHER 300
Query: 301 PSVYAFYSEQPDFSGHKYGPFGPEESSYGSPFTPAKRPKRKVAPKRRQERPVAPPKKRRR 360
PSVYAFYSEQPDFSGHKYGPFGPE
Sbjct: 301 PSVYAFYSEQPDFSGHKYGPFGPE------------------------------------ 324
Query: 361 KIHRMDHYAAETRQDKMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCD 420
MTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCD
Sbjct: 325 ----------------MTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCD 368
Query: 421 RTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQH 480
RTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQH
Sbjct: 369 RTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQH 428
Query: 481 LPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVF 540
LPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVF
Sbjct: 429 LPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVF 488
Query: 541 VGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEV 600
VGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEV
Sbjct: 489 VGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEV 548
Query: 601 TRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTEERHLLYGRPAVLYRT 660
TRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTEERHLLYGRPAVLYRT
Sbjct: 549 TRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTEERHLLYGRPAVLYRT 608
Query: 661 RYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCL 720
RYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCL
Sbjct: 609 RYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCL 668
Query: 721 AYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASER 780
AYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASER
Sbjct: 669 AYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASER 728
Query: 781 NGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGP 840
NGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGP
Sbjct: 729 NGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGP 788
Query: 841 LSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYPE 900
LSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYPE
Sbjct: 789 LSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYPE 848
Query: 901 ILTLKTYLHTYESEI 915
ILTLKTYLHTYESEI
Sbjct: 849 ILTLKTYLHTYESEI 863
>gi|195947389 autotaxin isoform 3 preproprotein [Homo sapiens]
Length = 888
Score = 1795 bits (4648), Expect = 0.0
Identities = 863/940 (91%), Positives = 863/940 (91%), Gaps = 77/940 (8%)
Query: 1 MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCK 60
MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCK
Sbjct: 1 MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCK 60
Query: 61 GRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHC 120
GRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHC
Sbjct: 61 GRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHC 120
Query: 121 SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK 180
SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK
Sbjct: 121 SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK 180
Query: 181 KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA 240
KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA
Sbjct: 181 KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA 240
Query: 241 TFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHER 300
TFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHER
Sbjct: 241 TFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHER 300
Query: 301 PSVYAFYSEQPDFSGHKYGPFGPEESSYGSPFTPAKRPKRKVAPKRRQERPVAPPKKRRR 360
PSVYAFYSEQPDFSGHKYGPFGPE
Sbjct: 301 PSVYAFYSEQPDFSGHKYGPFGPE------------------------------------ 324
Query: 361 KIHRMDHYAAETRQDKMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCD 420
MTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCD
Sbjct: 325 ----------------MTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCD 368
Query: 421 RTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQH 480
RTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQH
Sbjct: 369 RTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQH 428
Query: 481 LPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVF 540
LPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVF
Sbjct: 429 LPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVF 488
Query: 541 VGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEV 600
VGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEV
Sbjct: 489 VGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEV 548
Query: 601 TRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTE--------------- 645
TRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTE
Sbjct: 549 TRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTEAETRKFRGSRNENKE 608
Query: 646 ----------ERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVS 695
ERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVS
Sbjct: 609 NINGNFEPRKERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVS 668
Query: 696 SVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMV 755
SVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMV
Sbjct: 669 SVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMV 728
Query: 756 PMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIP 815
PMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIP
Sbjct: 729 PMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIP 788
Query: 816 VPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKWVEELMKMH 875
VPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKWVEELMKMH
Sbjct: 789 VPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKWVEELMKMH 848
Query: 876 TARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESEI 915
TARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESEI
Sbjct: 849 TARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESEI 888
>gi|111160296 ectonucleotide pyrophosphatase/phosphodiesterase 3
[Homo sapiens]
Length = 875
Score = 771 bits (1991), Expect = 0.0
Identities = 378/887 (42%), Positives = 544/887 (61%), Gaps = 91/887 (10%)
Query: 57 GSCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEEN 116
GSC+ +CF+ G +CRCD CK CC DF++ C+++ R W C K RCGE R E +
Sbjct: 52 GSCRKKCFDASFRGLENCRCDVACKDRGDCCWDFEDTCVESTRIWMCNKFRCGETRLEAS 111
Query: 117 ACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRA 176
C CS+DCL R DCC +Y+ VC+GE+ W++++C+ + ++CP GF PP+I+FS+DGFRA
Sbjct: 112 LCSCSDDCLQRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGFDLPPVILFSMDGFRA 171
Query: 177 SYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDP 236
Y+ +MPNI KL++CG HS YMR +YPTKTFPN YT+ TGLYPESHGI+ N+MYD
Sbjct: 172 EYLYTWDTLMPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDV 231
Query: 237 VFDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFW------------------SV 278
+ F L +E+ N WW GQP+W+TA QG+KA T+FW +
Sbjct: 232 NLNKNFSLSSKEQNNPAWWHGQPMWLTAMYQGLKAATYFWPGSEVAINGSFPSIYMPYNG 291
Query: 279 VIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEESSYGSPFTPAKRP 338
+P E RI T+L+WL LP ERP Y Y E+PD SGH G
Sbjct: 292 SVPFEERISTLLKWLDLPKAERPRFYTMYFEEPDSSGHAGG------------------- 332
Query: 339 KRKVAPKRRQERPVAPPKKRRRKIHRMDHYAAETRQDKMTNPLREIDKIVGQLMDGLKQL 398
PV+ ++ L+ +D G LM+GLKQ
Sbjct: 333 ------------PVSA---------------------RVIKALQVVDHAFGMLMEGLKQR 359
Query: 399 KLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYD-- 456
LH CVN+I + DHGM+ C++ E++++Y ++ + G RIR+ +N +D
Sbjct: 360 NLHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINFFYMYEGPAPRIRA---HNIPHDFF 416
Query: 457 ---PKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDV 513
+ I+ NL+C+KPDQHFKPYL LPKRLHYA N RI+ +HL V+++W L V
Sbjct: 417 SFNSEEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNVRIDKVHLFVDQQW------LAV 470
Query: 514 YKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKP 573
K + C G+HG++N+ SM+ +F+ +G +FK KT+V PFENIE+YN+MCDLL ++P
Sbjct: 471 RSKSNTNCG-GGNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFENIEVYNLMCDLLRIQP 529
Query: 574 APNNGTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDE 633
APNNGTHGSLNHLL+ + P+ EEV++ + G L C C ++ +L++
Sbjct: 530 APNNGTHGSLNHLLKVPFYEPSHAEEVSKFSVCGFANPLPTESLDCFCPH-LQNSTQLEQ 588
Query: 634 LNKRLHTKG----STEERHLLYGRPAVLYRT-RYDILYHTDFESGYSEIFLMPLWTSYTV 688
+N+ L+ +T + +L +GRP VL + + +LYH ++ SG+ + MP+W+SYTV
Sbjct: 589 VNQMLNLTQEEITATVKVNLPFGRPRVLQKNVDHCLLYHREYVSGFGKAMRMPMWSSYTV 648
Query: 689 SKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDA 748
+ + S +P + C+R DVRV PS SQ C Y DK +++GFL+PP + + +++YDA
Sbjct: 649 PQLGDTSPLPPTVPDCLRADVRVPPSESQKCSFYLADKNITHGFLYPPASNRTSDSQYDA 708
Query: 749 FLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQY 808
+ +N+VPMY F+++W+YF VL+ K+A+ERNGVNV+SGPIFDY+YDG D D+I ++
Sbjct: 709 LITSNLVPMYEEFRKMWDYFHSVLLIKHATERNGVNVVSGPIFDYNYDGHFDAPDEITKH 768
Query: 809 VEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKWV 868
+ + +P+PTHY+ ++TSC + + + C G L V FI+PHRP N ESC + E+ WV
Sbjct: 769 LANTDVPIPTHYFVVLTSCKNKSHTPENCPGWLDVLPFIIPHRPTNVESCPEGKPEALWV 828
Query: 869 EELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESEI 915
EE H ARVRD+E LT LDF++ + EIL LKTYL T+E+ I
Sbjct: 829 EERFTAHIARVRDVELLTGLDFYQDKVQPVSEILQLKTYLPTFETTI 875
>gi|170650661 ectonucleotide pyrophosphatase/phosphodiesterase 1
[Homo sapiens]
Length = 925
Score = 738 bits (1904), Expect = 0.0
Identities = 376/883 (42%), Positives = 518/883 (58%), Gaps = 91/883 (10%)
Query: 58 SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENA 117
SCKGRCFE +CRCD C +CC D+ E C++ W C K RCGE R +
Sbjct: 107 SCKGRCFERTFG---NCRCDAACVELGNCCLDYQETCIEPEHIWTCNKFRCGEKRLTRSL 163
Query: 118 CHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRAS 177
C CS+DC +GDCC NY VC+GE WV++ CE I +CPAGF PP ++FS+DGFRA
Sbjct: 164 CACSDDCKDKGDCCINYSSVCQGEKSWVEEPCESINEPQCPAGFETPPTLLFSLDGFRAE 223
Query: 178 YMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPV 237
Y+ ++P I KL+ CGT++ MRPVYPTKTFPN Y++ TGLYPESHGI+ N MYDP
Sbjct: 224 YLHTWGGLLPVISKLKKCGTYTKNMRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPK 283
Query: 238 FDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFW------------------SVV 279
+A+F L+ +EKFN W+ G+P+W+TA QG+K+GTFFW +
Sbjct: 284 MNASFSLKSKEKFNPEWYKGEPIWVTAKYQGLKSGTFFWPGSDVEINGIFPDIYKMYNGS 343
Query: 280 IPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEESSYGSPFTPAKRPK 339
+P E RIL +LQWL LP ERP Y Y E+PD SGH YGP E
Sbjct: 344 VPFEERILAVLQWLQLPKDERPHFYTLYLEEPDSSGHSYGPVSSE--------------- 388
Query: 340 RKVAPKRRQERPVAPPKKRRRKIHRMDHYAAETRQDKMTNPLREIDKIVGQLMDGLKQLK 399
+ L+ +D +VG LMDGLK+L
Sbjct: 389 -------------------------------------VIKALQRVDGMVGMLMDGLKELN 411
Query: 400 LHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKY--DP 457
LHRC+N+I + DHGME +C + +L+ YL +V +I ++ G R+R + Y +
Sbjct: 412 LHRCLNLILISDHGMEQGSCKKYIYLNKYLGDVKNIKVIYGPAARLRPSDVPDKYYSFNY 471
Query: 458 KAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKP 517
+ I NL+C++P+QHFKPYLK LPKRLH+A + RIE + ++ +W +A P + +K
Sbjct: 472 EGIARNLSCREPNQHFKPYLKHFLPKRLHFAKSDRIEPLTFYLDPQWQLALNPSE--RKY 529
Query: 518 SGKCFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNN 577
G F HG DN ++MQ +FVGYG FK+ + FENIE+YN+MCDLL L PAPNN
Sbjct: 530 CGSGF----HGSDNVFSNMQALFVGYGPGFKHGIEADTFENIEVYNLMCDLLNLTPAPNN 585
Query: 578 GTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKVEP-KNKLDELNK 636
GTHGSLNHLL+ + P P+EV P +LGC+C+ + P ++ + N
Sbjct: 586 GTHGSLNHLLKNPVYTPKHPKEV-HPLVQCPFTRNPRDNLGCSCNPSILPIEDFQTQFNL 644
Query: 637 RLHTKGSTEERHLLYGRPAVLYR-TRYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVS 695
+ + + L YGRP VL + +L F SGYS+ LMPLWTSYTV + S
Sbjct: 645 TVAEEKIIKHETLPYGRPRVLQKENTICLLSQHQFMSGYSQDILMPLWTSYTVDRNDSFS 704
Query: 696 SVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKY-DAFLVTNM 754
+ + ++C+ D R+ S C YKN+ ++SYGFL PP L+ + Y +A L TN+
Sbjct: 705 T--EDFSNCLYQDFRIPLSPVHKCSFYKNNTKVSYGFLSPPQLNKNSSGIYSEALLTTNI 762
Query: 755 VPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQ---YVEG 811
VPMY +F+ +W YF L++KYA ERNGVNV+SGP+FD+DYDG D+ + ++Q +
Sbjct: 763 VPMYQSFQVIWRYFHDTLLRKYAEERNGVNVVSGPVFDFDYDGRCDSLENLRQKRRVIRN 822
Query: 812 SSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKWVEEL 871
I +PTH++ ++TSC D +Q C+ L +FILPHR DN ESC + +S WVEEL
Sbjct: 823 QEILIPTHFFIVLTSCKDTSQTPLHCEN-LDTLAFILPHRTDNSESCVHGKHDSSWVEEL 881
Query: 872 MKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESE 914
+ +H AR+ D+EH+T L F+++ +IL LKT+L T+ E
Sbjct: 882 LMLHRARITDVEHITGLSFYQQRKEPVSDILKLKTHLPTFSQE 924
>gi|7662358 ectonucleotide pyrophosphatase/phosphodiesterase 4
(putative function) [Homo sapiens]
Length = 453
Score = 172 bits (436), Expect = 1e-42
Identities = 130/445 (29%), Positives = 191/445 (42%), Gaps = 95/445 (21%)
Query: 164 PPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYP 223
P L++ S DGFRA Y+K P+++ G +++ V+ TKTFPN Y++ TGLY
Sbjct: 26 PKLLLVSFDGFRADYLKNYE--FPHLQNFIKEGVLVEHVKNVFITKTFPNHYSIVTGLYE 83
Query: 224 ESHGIVGNSMYDPVFDATFHLRGREKFNHRWWG-GQPLWITATKQGVKAG---------- 272
ESHGIV NSMYD V H + WW P+W+T Q ++
Sbjct: 84 ESHGIVANSMYDAVTKK--HFSDSNDKDPFWWNEAVPIWVTNQLQENRSSAAAMWPGTDV 141
Query: 273 -------TFF--WSVVIPHERRILTILQWLTLPDHERPSVYA-FYSEQPDFSGHKYGPFG 322
++F ++ + E R+ I WL + P +A Y E+PD SGHKYG
Sbjct: 142 PIHDTISSYFMNYNSSVSFEERLNNITMWLN--NSNPPVTFATLYWEEPDASGHKYG--- 196
Query: 323 PEESSYGSPFTPAKRPKRKVAPKRRQERPVAPPKKRRRKIHRMDHYAAETRQDKMTNPLR 382
PE+ ++ M+ L+
Sbjct: 197 PED------------------------------------------------KENMSRVLK 208
Query: 383 EIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTL 442
+ID ++G L+ LK L L +NVI DHGM + DR L + + + + +
Sbjct: 209 KIDDLIGDLVQRLKMLGLWENLNVIITSDHGMTQCSQDRLINLDSCIDHSYYTLIDLSPV 268
Query: 443 GRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVER 502
I K + Y+ K H YLK+ +P R +Y +N RI+ I L+ +
Sbjct: 269 AAILPKINRTEVYNK--------LKNCSPHMNVYLKEDIPNRFYYQHNDRIQPIILVADE 320
Query: 503 RWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKVPPFENIELY 562
W + V + S K GDHG+DN + SM +G F K +++Y
Sbjct: 321 GWTI------VLNESSQKL---GDHGYDNSLPSMHPFLAAHGPAFHKGYKHSTINIVDIY 371
Query: 563 NVMCDLLGLKPAPNNGTHGSLNHLL 587
+MC +LGLKP PNNGT G LL
Sbjct: 372 PMMCHILGLKPHPNNGTFGHTKCLL 396
>gi|11034849 ectonucleotide pyrophosphatase/phosphodiesterase 5
(putative function) [Homo sapiens]
Length = 477
Score = 160 bits (404), Expect = 7e-39
Identities = 117/443 (26%), Positives = 189/443 (42%), Gaps = 90/443 (20%)
Query: 166 LIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPES 225
+++ S DGFR Y+ K P+ + G H + V+ TKT+PN YTL TGL+ E+
Sbjct: 30 VLLVSFDGFRWDYLYKVPT--PHFHYIMKYGVHVKQVTNVFITKTYPNHYTLVTGLFAEN 87
Query: 226 HGIVGNSMYDPVFDATFHLRGREKFNHRWWG-GQPLWITATKQGVKAGTFFW-------- 276
HGIV N M+DP+ + +F L ++ ++W P+WIT + G +G W
Sbjct: 88 HGIVANDMFDPIRNKSFSLDHMNIYDSKFWEEATPIWITNQRAGHTSGAAMWPGTDVKIH 147
Query: 277 ----------SVVIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEES 326
+ + E R+ I++W T E ++ Y E PD GH GP
Sbjct: 148 KRFPTHYMPYNESVSFEDRVAKIIEWFT--SKEPINLGLLYWEDPDDMGHHLGP------ 199
Query: 327 SYGSPFTPAKRPKRKVAPKRRQERPVAPPKKRRRKIHRMDHYAAETRQDKMTNPLREIDK 386
+ P+ P + +IDK
Sbjct: 200 ----------------------DSPLMGPV------------------------ISDIDK 213
Query: 387 IVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIR 446
+G L+ LK+ KL +N+I DHGM + +R L YL D TL+ + +
Sbjct: 214 KLGYLIQMLKKAKLWNTLNLIITSDHGMTQCSEERLIELDQYLDK-DHYTLIDQS--PVA 270
Query: 447 SKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHV 506
+ K+D + LT P+ Y K+ +P+R HY N RI+ I + + WH+
Sbjct: 271 AILPKEGKFDE--VYEALTHAHPN--LTVYKKEDVPERWHYKYNSRIQPIIAVADEGWHI 326
Query: 507 ARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMC 566
+ D F G+HG+DN + M +F+ +G F+ + +LY ++C
Sbjct: 327 LQNKSDD--------FLLGNHGYDNALADMHPIFLAHGPAFRKNFSKEAMNSTDLYPLLC 378
Query: 567 DLLGLKPAPNNGTHGSLNHLLRT 589
LL + P+NG+ ++ LL +
Sbjct: 379 HLLNITAMPHNGSFWNVQDLLNS 401
>gi|23503267 ectonucleotide pyrophosphatase/phosphodiesterase 6
[Homo sapiens]
Length = 440
Score = 154 bits (389), Expect = 4e-37
Identities = 118/466 (25%), Positives = 211/466 (45%), Gaps = 93/466 (19%)
Query: 163 RPPLIIFSVDGFRASYMK-KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGL 221
R L++F +DGFR+ Y+ + + +P +++ S G Y+ P +P+ ++PN YTL TG
Sbjct: 23 RRKLLVFLLDGFRSDYISDEALESLPGFKEIVSRGVKVDYLTPDFPSLSYPNYYTLMTGR 82
Query: 222 YPESHGIVGNSMYDPVFDATFHLR-GREKFNHRWWGG-QPLWITATKQGVKAGTFFWSVV 279
+ E H ++GN M+DP + +F + ++ WW G +PLW+T TK K ++W
Sbjct: 83 HCEVHQMIGNYMWDPTTNKSFDIGVNKDSLMPLWWNGSEPLWVTLTKAKRKVYMYYWPGC 142
Query: 280 IPHERRILTI-----LQWLTLPDH----------------ERPSVYAFYSEQPDFSGHKY 318
E IL + L++ +P R + A Y E+ D GH Y
Sbjct: 143 ---EVEILGVRPTYCLEYKNVPTDINFANAVSDALDSFKSGRADLAAIYHERIDVEGHHY 199
Query: 319 GPFGPEESSYGSPFTPAKRPKRKVAPKRRQERPVAPPKKRRRKIHRMDHYAAETRQDKMT 378
GP P+RK A
Sbjct: 200 GPAS---------------PQRKDA----------------------------------- 209
Query: 379 NPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVT-CDRTEFLSNYLTNVDDITL 437
L+ +D ++ + +++ L +NVI DHGM D+ D+ L+ Y++ ++D+
Sbjct: 210 --LKAVDTVLKYMTKWIQERGLQDRLNVIIFSDHGMTDIFWMDKVIELNKYIS-LNDLQQ 266
Query: 438 VPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIH 497
V G + S + K+ I L+ +H Y K+ +P R +Y + + +
Sbjct: 267 VKDR-GPVVSLWPAPGKHSE--IYNKLSTV---EHMTVYEKEAIPSRFYYKKGKFVSPLT 320
Query: 498 LLVERRWHVA--RKPLDVYKKPSGKC--FFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKV 553
L+ + W + R+ L + +G+ + +G HG+DN++ M+ +F+ +G FK +
Sbjct: 321 LVADEGWFITENREMLPFWMNSTGRREGWQRGWHGYDNELMDMRGIFLAFGPDFKSNFRA 380
Query: 554 PPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLL--RTNTFRPTMP 597
P ++++YNVMC+++G+ P PNNG+ + +L R +T P P
Sbjct: 381 APIRSVDVYNVMCNVVGITPLPNNGSWSRVMCMLKGRASTAPPVWP 426
>gi|45545421 ectonucleotide pyrophosphatase/phosphodiesterase 7
[Homo sapiens]
Length = 458
Score = 154 bits (388), Expect = 5e-37
Identities = 132/468 (28%), Positives = 202/468 (43%), Gaps = 119/468 (25%)
Query: 166 LIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPES 225
L++ S DGFR +Y + PN++ + G + YM P + T T P +TL TG Y E+
Sbjct: 33 LLLVSFDGFRWNYDQDVDT--PNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGKYIEN 90
Query: 226 HGIVGNSMYDPV------FDATFHLRGREKFNHRWW--GGQPLWITATKQGVKAGTFFW- 276
HG+V N Y+ + AT ++ RWW G P+WITA +QG++AG+FF+
Sbjct: 91 HGVVHNMYYNTTSKVKLPYHATLGIQ-------RWWDNGSVPIWITAQRQGLRAGSFFYP 143
Query: 277 -------SVVIPHERR----------------ILTILQWLTLPDHERPSVYAFYSEQPDF 313
V + R+ I T++ W T D + + Y +PD
Sbjct: 144 GGNVTYQGVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFTEEDLD---LVTLYFGEPDS 200
Query: 314 SGHKYGPFGPEESSYGSPFTPAKRPKRKVAPKRRQERPVAPPKKRRRKIHRMDHYAAETR 373
+GH+YGP PE RR++
Sbjct: 201 TGHRYGPESPE----------------------------------RREM----------- 215
Query: 374 QDKMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDV---TCDRTEF--LSNY 428
+R++D+ VG L + + + L +N+I DHGM V D EF N+
Sbjct: 216 -------VRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTTVDKRAGDLVEFHKFPNF 268
Query: 429 -LTNVDDITLVPGTLGRIRSKFSNNAK-YDPKAIIANLTCKKPDQHFKPYLKQHLPKRLH 486
+++ L G G + K K YD L P H Y K+ P+ H
Sbjct: 269 TFRDIEFELLDYGPNGMLLPKEGRLEKVYDA------LKDAHPKLHV--YKKEAFPEAFH 320
Query: 487 YANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGST 546
YANN R+ + L+ +V ++V F G+HGFDNK M+T+F G +
Sbjct: 321 YANNPRVTPL-LMYSDLGYVIHGRINVQ-------FNNGEHGFDNKDMDMKTIFRAVGPS 372
Query: 547 FKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRP 594
F+ +V PFE++ +Y +MC LLG+ P N+G +L +L T + P
Sbjct: 373 FRAGLEVEPFESVHVYELMCRLLGIVPEANDGHLATLLPMLHTESALP 420
>gi|239755573 PREDICTED: similar to ectonucleotide
pyrophosphatase/phosphodiesterase 5 (putative function)
[Homo sapiens]
Length = 661
Score = 60.5 bits (145), Expect = 7e-09
Identities = 54/223 (24%), Positives = 88/223 (39%), Gaps = 33/223 (14%)
Query: 381 LREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTE---FLSNYLTNVD---- 433
++++D+ + L+ ++ L + VI DHGM V LSNY+ D
Sbjct: 307 IQQLDRTIWYLVGATEKHSL-QSPQVIITXDHGMMTVKKRPNVNKIXLSNYIKFRDWVKF 365
Query: 434 DITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRI 493
DI G + A Y K H Y K+ P+ H A + R+
Sbjct: 366 DIVGYGGFGLPLPKLGQEEALYQ--------ALKNAHPHLHIYKKEEFPEHFHLAKHDRV 417
Query: 494 EDIHLLVERRWHVARKPLDVYKK----PSGK-------------CFFQGDHGFDNKVNSM 536
I + + + + + P+ + CF +G HGFDN + M
Sbjct: 418 LPIVMYANSSYRYLDSSMRTFNETRTFPTDQPDSLREQDARIIMCFNKGSHGFDNVLMDM 477
Query: 537 QTVFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGT 579
+T+F +G FK F +I +Y +C LLG+ P +NG+
Sbjct: 478 KTIFRDFGPDFKKNGLAETFNSIHIYPFVCKLLGVXPQTHNGS 520
Score = 40.4 bits (93), Expect = 0.008
Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 18/129 (13%)
Query: 154 AAECPAGFVRPP-------LIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVY 206
A CPAG PP L++ S GFR + PN++ L G + Y+ P
Sbjct: 10 AIACPAGRPPPPREEEHSQLLLISFQGFRWDXDQDVDT--PNMDHLAGEGVKAKYLMPPL 67
Query: 207 PTKTFPNLYTLATG--LYPESHGIVGNSMYDP--VFDATFHLRGREK--FNHRWWGGQPL 260
T T P +T G L+ H ++ N M++ +++ +F ++ ++R L
Sbjct: 68 VTMTSPFHFTAMPGKLLWVRDHXVIHNMMFNTEMLWNCSFKTTQKKTQCXDNRVLS---L 124
Query: 261 WITATKQGV 269
WITA +QG+
Sbjct: 125 WITAQRQGL 133
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 53.5 bits (127), Expect = 9e-07
Identities = 27/81 (33%), Positives = 32/81 (39%), Gaps = 5/81 (6%)
Query: 58 SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENA 117
SC GRC E + C CD C+ Y CC DF +C K RC E
Sbjct: 29 SCAGRCGE-GYSRDATCNCDYNCQHYMECCPDFKRVCTAEL----SCKGRCFESFERGRE 83
Query: 118 CHCSEDCLARGDCCTNYQVVC 138
C C C CC +Y+ C
Sbjct: 84 CDCDAQCKKYDKCCPDYESFC 104
Score = 34.3 bits (77), Expect = 0.55
Identities = 12/35 (34%), Positives = 20/35 (57%)
Query: 107 RCGEVRNEENACHCSEDCLARGDCCTNYQVVCKGE 141
RCGE + + C+C +C +CC +++ VC E
Sbjct: 33 RCGEGYSRDATCNCDYNCQHYMECCPDFKRVCTAE 67
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 53.5 bits (127), Expect = 9e-07
Identities = 27/81 (33%), Positives = 32/81 (39%), Gaps = 5/81 (6%)
Query: 58 SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENA 117
SC GRC E + C CD C+ Y CC DF +C K RC E
Sbjct: 29 SCAGRCGE-GYSRDATCNCDYNCQHYMECCPDFKRVCTAEL----SCKGRCFESFERGRE 83
Query: 118 CHCSEDCLARGDCCTNYQVVC 138
C C C CC +Y+ C
Sbjct: 84 CDCDAQCKKYDKCCPDYESFC 104
Score = 34.3 bits (77), Expect = 0.55
Identities = 12/35 (34%), Positives = 20/35 (57%)
Query: 107 RCGEVRNEENACHCSEDCLARGDCCTNYQVVCKGE 141
RCGE + + C+C +C +CC +++ VC E
Sbjct: 33 RCGEGYSRDATCNCDYNCQHYMECCPDFKRVCTAE 67
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 49.3 bits (116), Expect = 2e-05
Identities = 20/37 (54%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
Query: 58 SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELC 94
SCKGRCFE E G +C CD CK Y CC D++ C
Sbjct: 28 SCKGRCFESFERGR-ECDCDAQCKKYDKCCPDYESFC 63
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 49.3 bits (116), Expect = 2e-05
Identities = 20/37 (54%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
Query: 58 SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELC 94
SCKGRCFE E G +C CD CK Y CC D++ C
Sbjct: 28 SCKGRCFESFERGR-ECDCDAQCKKYDKCCPDYESFC 63
>gi|88853069 vitronectin precursor [Homo sapiens]
Length = 478
Score = 41.6 bits (96), Expect = 0.003
Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 3/54 (5%)
Query: 43 PPTVLSDSPWTNISG--SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELC 94
P +L+ W ++ SCKGRC E C+CD LC Y SCC D+ C
Sbjct: 6 PLLILALLAWVALADQESCKGRCTEGFNVDKK-CQCDELCSYYQSCCTDYTAEC 58
Score = 37.4 bits (85), Expect = 0.064
Identities = 16/38 (42%), Positives = 18/38 (47%)
Query: 102 ECTKDRCGEVRNEENACHCSEDCLARGDCCTNYQVVCK 139
E K RC E N + C C E C CCT+Y CK
Sbjct: 22 ESCKGRCTEGFNVDKKCQCDELCSYYQSCCTDYTAECK 59
>gi|5174623 placental protein 11 precursor [Homo sapiens]
Length = 369
Score = 40.8 bits (94), Expect = 0.006
Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
Query: 58 SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELC 94
SC+GRC+E + C C+ C+ + +CC DF+ LC
Sbjct: 48 SCQGRCYEAFDKHH-QCHCNARCQEFGNCCKDFESLC 83
Score = 35.8 bits (81), Expect = 0.19
Identities = 15/50 (30%), Positives = 25/50 (50%), Gaps = 2/50 (4%)
Query: 107 RCGEVRNEENACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAE 156
RC E ++ + CHC+ C G+CC +++ +C H V + I E
Sbjct: 52 RCYEAFDKHHQCHCNARCQEFGNCCKDFESLC--SDHEVSHSSDAITKEE 99
>gi|4557733 latent transforming growth factor beta binding protein 2
[Homo sapiens]
Length = 1821
Score = 39.7 bits (91), Expect = 0.013
Identities = 41/170 (24%), Positives = 61/170 (35%), Gaps = 53/170 (31%)
Query: 44 PTVLSDSPWTNISGSC------------KGRCFELQEAGPP----DCRCDNLCKSYT--- 84
P V S TN GS KG C ++ E P D RC N SYT
Sbjct: 937 PGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQDINECRHPGTCPDGRCVNSPGSYTCLA 996
Query: 85 ---------SCCHDFDEL----------CLKTARGWECTKDRCGEVRNEENACHCSEDCL 125
C D +E C + C+ ++ EV ++E C ++C
Sbjct: 997 CEEGYRGQSGSCVDVNECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECA 1056
Query: 126 ARGDCCTNYQVVCKG--------ESHWVDDD---CEEIKAAE----CPAG 160
+R C T + +G +WV++D CE++ CP+G
Sbjct: 1057 SRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSG 1106
>gi|169217819 PREDICTED: similar to hCG1793095 [Homo sapiens]
Length = 167
Score = 37.7 bits (86), Expect = 0.049
Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 163 RPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLY 222
R L++ S D FR +Y + PN++ + G + YM P + T T P +TL TG Y
Sbjct: 30 RNKLLLVSFDSFRWNYEQDVDT--PNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGEY 87
>gi|239756564 PREDICTED: similar to hCG1793095 [Homo sapiens]
Length = 98
Score = 37.7 bits (86), Expect = 0.049
Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 163 RPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLY 222
R L++ S D FR +Y + PN++ + G + YM P + T T P +TL TG Y
Sbjct: 30 RNKLLLVSFDSFRWNYEQDVDT--PNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGEY 87
>gi|187608744 zinc finger protein 9 isoform 5 [Homo sapiens]
Length = 171
Score = 37.7 bits (86), Expect = 0.049
Identities = 29/108 (26%), Positives = 38/108 (35%), Gaps = 15/108 (13%)
Query: 60 KGRCFELQEAGPPDC--RCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENA 117
+GR F+ + PD RC C DE C RG KD C E + E
Sbjct: 32 RGRGFQFVSSSLPDICYRCGESGHLAKDCDLQEDEACYNCGRGGHIAKD-CKEPKREREQ 90
Query: 118 C--------HCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAEC 157
C H + DC D + GE + DC ++K C
Sbjct: 91 CCYNCGKPGHLARDC----DHADEQKCYSCGEFGHIQKDCTKVKCYRC 134
>gi|123702038 keratin associated protein 5-9 [Homo sapiens]
Length = 169
Score = 37.7 bits (86), Expect = 0.049
Identities = 23/89 (25%), Positives = 32/89 (35%), Gaps = 8/89 (8%)
Query: 58 SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENA 117
SC C G C+C + CK Y S C C + RG C + C + +
Sbjct: 81 SCCKPCCCSSGCGSSCCQC-SCCKPYCSQCSCCKPCCSSSGRGSSCCQSSCCKPCCSSSG 139
Query: 118 C-------HCSEDCLARGDCCTNYQVVCK 139
C C + C ++ CC CK
Sbjct: 140 CGSSCCQSSCCKPCCSQSRCCVPVCYQCK 168
>gi|209969800 RPE-spondin [Homo sapiens]
Length = 264
Score = 36.2 bits (82), Expect = 0.14
Identities = 19/68 (27%), Positives = 24/68 (35%), Gaps = 10/68 (14%)
Query: 80 CKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLARGDCCTNYQVVCK 139
C CC D C ARGW + C C + C GDCC +Y C
Sbjct: 22 CAEAGRCCPGRDPACF--ARGWRLDR--------VYGTCFCDQACRFTGDCCFDYDRACP 71
Query: 140 GESHWVDD 147
+V +
Sbjct: 72 ARPCFVGE 79
>gi|187608732 zinc finger protein 9 isoform 2 [Homo sapiens]
Length = 178
Score = 35.4 bits (80), Expect = 0.24
Identities = 29/111 (26%), Positives = 37/111 (33%), Gaps = 15/111 (13%)
Query: 57 GSCKGRCFELQEAGPPDC--RCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNE 114
G R F+ + PD RC C DE C RG KD C E + E
Sbjct: 36 GFTSDRGFQFVSSSLPDICYRCGESGHLAKDCDLQEDEACYNCGRGGHIAKD-CKEPKRE 94
Query: 115 ENAC--------HCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAEC 157
C H + DC D + GE + DC ++K C
Sbjct: 95 REQCCYNCGKPGHLARDC----DHADEQKCYSCGEFGHIQKDCTKVKCYRC 141
>gi|98985828 ADAM metallopeptidase domain 28 isoform 1 preproprotein
[Homo sapiens]
Length = 775
Score = 35.4 bits (80), Expect = 0.24
Identities = 20/98 (20%), Positives = 38/98 (38%), Gaps = 5/98 (5%)
Query: 103 CTKDRCGEVRNEENACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAA---ECPA 159
C C ++ + +CS C +G ++++ C+ E W+ DC++
Sbjct: 612 CINAECVDIEKAYKSTNCSSKC--KGHAVCDHELQCQCEEGWIPPDCDDSSVVFHFSIVV 669
Query: 160 GFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGT 197
G + P +IF V + K + L + GT
Sbjct: 670 GVLFPMAVIFVVVAMVIRHQSSREKQKKDQRPLSTTGT 707
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 35.0 bits (79), Expect = 0.32
Identities = 28/89 (31%), Positives = 38/89 (42%), Gaps = 11/89 (12%)
Query: 53 TNISGSCKGRCFELQEAGPP-DCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEV 111
TN+ GS + C E E GP +C N C C C+ T +ECT +
Sbjct: 2229 TNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAF---RCMNTFGSYECTCPIGYAL 2285
Query: 112 RNEENAC----HCSE---DCLARGDCCTN 133
R ++ C C+E DC +RG C N
Sbjct: 2286 REDQKMCKDLDECAEGLHDCESRGMMCKN 2314
>gi|23308689 RNA pseudouridylate synthase domain containing 2 [Homo
sapiens]
Length = 545
Score = 35.0 bits (79), Expect = 0.32
Identities = 23/53 (43%), Positives = 28/53 (52%), Gaps = 4/53 (7%)
Query: 320 PFGPEESSYGSPFTPAKRPKRKVAPKRRQERPVAPPKKRRRKIHRMDHYAAET 372
P G E S +P P K KR+ A + ER V PPKKRR + D + AET
Sbjct: 83 PVGGEHPSAAAP-GPGKHKKRRGATR---ERVVPPPKKRRTGVSFGDEHFAET 131
>gi|190358524 follistatin-like 5 isoform c [Homo sapiens]
Length = 837
Score = 34.7 bits (78), Expect = 0.42
Identities = 23/95 (24%), Positives = 41/95 (43%), Gaps = 19/95 (20%)
Query: 46 VLSDSPWTNISGSCKGR-------CFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTA 98
++ D P+ GSC+ + C +E G +C C +LCK + + +C
Sbjct: 55 MIQDGPF----GSCENKYCGLGRHCVTSRETGQAECACMDLCKRH------YKPVCGSDG 104
Query: 99 RGWE--CTKDRCGEVRNEENACHCSEDCLARGDCC 131
+E C R ++ ++ +EDC +GD C
Sbjct: 105 EFYENHCEVHRAACLKKQKITIVHNEDCFFKGDKC 139
>gi|190358522 follistatin-like 5 isoform b [Homo sapiens]
Length = 846
Score = 34.7 bits (78), Expect = 0.42
Identities = 23/95 (24%), Positives = 41/95 (43%), Gaps = 19/95 (20%)
Query: 46 VLSDSPWTNISGSCKGR-------CFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTA 98
++ D P+ GSC+ + C +E G +C C +LCK + + +C
Sbjct: 55 MIQDGPF----GSCENKYCGLGRHCVTSRETGQAECACMDLCKRH------YKPVCGSDG 104
Query: 99 RGWE--CTKDRCGEVRNEENACHCSEDCLARGDCC 131
+E C R ++ ++ +EDC +GD C
Sbjct: 105 EFYENHCEVHRAACLKKQKITIVHNEDCFFKGDKC 139
>gi|190358520 follistatin-like 5 isoform a [Homo sapiens]
Length = 847
Score = 34.7 bits (78), Expect = 0.42
Identities = 23/95 (24%), Positives = 41/95 (43%), Gaps = 19/95 (20%)
Query: 46 VLSDSPWTNISGSCKGR-------CFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTA 98
++ D P+ GSC+ + C +E G +C C +LCK + + +C
Sbjct: 56 MIQDGPF----GSCENKYCGLGRHCVTSRETGQAECACMDLCKRH------YKPVCGSDG 105
Query: 99 RGWE--CTKDRCGEVRNEENACHCSEDCLARGDCC 131
+E C R ++ ++ +EDC +GD C
Sbjct: 106 EFYENHCEVHRAACLKKQKITIVHNEDCFFKGDKC 140
>gi|93102379 low density lipoprotein-related protein 1B precursor
[Homo sapiens]
Length = 4599
Score = 33.5 bits (75), Expect = 0.93
Identities = 27/92 (29%), Positives = 37/92 (40%), Gaps = 13/92 (14%)
Query: 80 CKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENAC---HCSEDCLARGDC----CT 132
C CHD LCL T G R + E+N C + S + + +C C
Sbjct: 2468 CALLNGGCHD---LCLLTPNGRVNCSCRGDRILLEDNRCVTKNSSCNAYSEFECGNGECI 2524
Query: 133 NYQVVCKGESHWVDDDCEEIKAAE---CPAGF 161
+YQ+ C G H D E++ E C GF
Sbjct: 2525 DYQLTCDGIPHCKDKSDEKLLYCENRSCRRGF 2556
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.438
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,189,531
Number of Sequences: 37866
Number of extensions: 2034934
Number of successful extensions: 5333
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 5152
Number of HSP's gapped (non-prelim): 170
length of query: 915
length of database: 18,247,518
effective HSP length: 111
effective length of query: 804
effective length of database: 14,044,392
effective search space: 11291691168
effective search space used: 11291691168
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.