Search of human proteins with 91199546

Search of human proteins with 91199546

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|91199546 CD63 antigen isoform B [Homo sapiens]
         (236 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|91199546 CD63 antigen isoform B [Homo sapiens]                     477   e-135
gi|4502679 CD63 antigen isoform A [Homo sapiens]                      472   e-133
gi|21265104 tetraspanin 7 [Homo sapiens]                              136   1e-32
gi|5729941 tetraspanin 9 [Homo sapiens]                               129   2e-30
gi|30425534 tetraspanin 33 [Homo sapiens]                             126   1e-29
gi|68800005 tetraspanin 4 isoform a [Homo sapiens]                    124   9e-29
gi|4507543 tetraspanin 4 isoform a [Homo sapiens]                     124   9e-29
gi|68800018 tetraspanin 4 isoform a [Homo sapiens]                    124   9e-29
gi|68800024 tetraspanin 4 isoform a [Homo sapiens]                    124   9e-29
gi|68800011 tetraspanin 4 isoform a [Homo sapiens]                    124   9e-29
gi|68799997 tetraspanin 4 isoform a [Homo sapiens]                    124   9e-29
gi|87159824 CD151 antigen [Homo sapiens]                              120   1e-27
gi|87159822 CD151 antigen [Homo sapiens]                              120   1e-27
gi|21237751 CD151 antigen [Homo sapiens]                              120   1e-27
gi|21237748 CD151 antigen [Homo sapiens]                              120   1e-27
gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens]        119   2e-27
gi|5032201 transmembrane 4 superfamily member 8 isoform 1 [Homo ...   108   4e-24
gi|50511934 transmembrane 4 superfamily member 17 isoform b [Hom...   107   9e-24
gi|68800032 tetraspanin 4 isoform b [Homo sapiens]                    107   1e-23
gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens]        106   2e-23
gi|54859560 transmembrane 4 superfamily member 17 isoform a [Hom...   106   2e-23
gi|54859505 transmembrane 4 superfamily member 17 isoform c [Hom...   105   3e-23
gi|190194420 tetraspanin 14 isoform 1 [Homo sapiens]                  105   3e-23
gi|122937466 tetraspanin 11 [Homo sapiens]                            102   4e-22
gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens]       101   5e-22
gi|42476204 tetraspanin 18 isoform 2 [Homo sapiens]                    98   7e-21
gi|6912530 transmembrane 4 superfamily member 15 [Homo sapiens]        97   2e-20
gi|10834972 CD53 antigen [Homo sapiens]                                96   4e-20
gi|91106727 CD53 antigen [Homo sapiens]                                96   4e-20
gi|6912528 transmembrane 4 superfamily member 12 [Homo sapiens]        94   8e-20

>gi|91199546 CD63 antigen isoform B [Homo sapiens]
          Length = 236

 Score =  477 bits (1228), Expect = e-135
 Identities = 236/236 (100%), Positives = 236/236 (100%)

Query: 1   MAVEGGMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAV 60
           MAVEGGMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAV
Sbjct: 1   MAVEGGMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAV 60

Query: 61  GVFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFR 120
           GVFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFR
Sbjct: 61  GVFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFR 120

Query: 121 QQMENYPKNNHTASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGIN 180
           QQMENYPKNNHTASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGIN
Sbjct: 121 QQMENYPKNNHTASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGIN 180

Query: 181 FNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFVLGIVFACCLVKSIRSGYEVM 236
           FNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFVLGIVFACCLVKSIRSGYEVM
Sbjct: 181 FNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFVLGIVFACCLVKSIRSGYEVM 236


>gi|4502679 CD63 antigen isoform A [Homo sapiens]
          Length = 238

 Score =  472 bits (1215), Expect = e-133
 Identities = 236/238 (99%), Positives = 236/238 (99%), Gaps = 2/238 (0%)

Query: 1   MAVEGGMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAV 60
           MAVEGGMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAV
Sbjct: 1   MAVEGGMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAV 60

Query: 61  GVFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFR 120
           GVFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFR
Sbjct: 61  GVFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFR 120

Query: 121 QQMENYPKNNHTASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGIN 180
           QQMENYPKNNHTASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGIN
Sbjct: 121 QQMENYPKNNHTASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGIN 180

Query: 181 FNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAF--VLGIVFACCLVKSIRSGYEVM 236
           FNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAF  VLGIVFACCLVKSIRSGYEVM
Sbjct: 181 FNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFVEVLGIVFACCLVKSIRSGYEVM 238


>gi|21265104 tetraspanin 7 [Homo sapiens]
          Length = 249

 Score =  136 bits (343), Expect = 1e-32
 Identities = 73/237 (30%), Positives = 124/237 (52%), Gaps = 10/237 (4%)

Query: 9   CVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAVGVFLFLVA 68
           C+K LL +    F    V L+AVGV  +L L   I   A   +  P V+I  G  + +  
Sbjct: 14  CLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAPYVLIGTGTTIVVFG 73

Query: 69  FVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYPK 128
             GC   C+ +  ++  +A+FLSL+ L E+ A I+G+VFR ++   F   +   M+ Y  
Sbjct: 74  LFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQTYNG 133

Query: 129 NNHTASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGC------GINFN 182
           N+  +  +D +Q    CCG  NYT+W   P   ++ +P SCC+N T  C       +   
Sbjct: 134 NDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEHGIPPSCCMNET-DCNPQDLHNLTVA 192

Query: 183 EKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAF--VLGIVFACCLVKSIRSG-YEVM 236
              ++++GC + +  ++  N+ ++A  A GIAF  ++G++ ACCL + I +  YE++
Sbjct: 193 ATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRFITANQYEMV 249


>gi|5729941 tetraspanin 9 [Homo sapiens]
          Length = 239

 Score =  129 bits (325), Expect = 2e-30
 Identities = 75/232 (32%), Positives = 123/232 (53%), Gaps = 12/232 (5%)

Query: 5   GGMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQ---TIIQGATPGSLLPVVIIAVG 61
           G + C+K+++++  L F  C  GL+  GVG  L +SQ        + P      ++IA+G
Sbjct: 4   GCLCCLKYMMFLFNLIFWLCGCGLL--GVGIWLSVSQGNFATFSPSFPSLSAANLVIAIG 61

Query: 62  VFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQ 121
             + +  F+GC GA KEN CL+++F I L +I+L E+   I  +V+ DKV      + ++
Sbjct: 62  TIVMVTGFLGCLGAIKENKCLLLSFFIVLLVILLAELILLILFFVYMDKVNENAKKDLKE 121

Query: 122 QMENYPKNNHTA--SILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGI 179
            +  Y   N+    +  + +QA+ +CCG  +YTDW   P + +N VPD CC+  + GCG 
Sbjct: 122 GLLLYHTENNVGLKNAWNIIQAEMRCCGVTDYTDW--YPVLGENTVPDRCCMENSQGCGR 179

Query: 180 NFNEKAIHKEGCVEKIGGWL--RKNVLVVAAAALGIAFVLGIVFACCLVKSI 229
           N     + + GC EK+  W    K+VL      + I  +LG+ F+  L + I
Sbjct: 180 NAT-TPLWRTGCYEKVKMWFDDNKHVLGTVGMCILIMQILGMAFSMTLFQHI 230


>gi|30425534 tetraspanin 33 [Homo sapiens]
          Length = 283

 Score =  126 bits (317), Expect = 1e-29
 Identities = 75/245 (30%), Positives = 126/245 (51%), Gaps = 25/245 (10%)

Query: 10  VKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAVGVFLFLVAF 69
           VK+LL+   + F   ++ ++AVGV A+L+                +++I VGV +FL+ F
Sbjct: 22  VKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACLAVDPA-ILLIVVGVLMFLLTF 80

Query: 70  VGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYPKN 129
            GC G+ +EN CL+ TF++ L+ + L+++AA I G+VF DK   + +      + +Y  +
Sbjct: 81  CGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHYRDD 140

Query: 130 NHTASILDRMQADFKCCGAANYTDW---------EKIPSMSKNRVPDSCC--------IN 172
               +++D  Q  F CCG  +Y DW         E  PS  +  VP SCC        IN
Sbjct: 141 LDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQAVIN 200

Query: 173 VTVGCGINFNE-----KAIHKEGCVEKIGGWLRKNVLVVAAAALGIAF--VLGIVFACCL 225
              G G+   +     K I+  GC++K+  W+  N+ ++   ALG+A   ++GI+ +  L
Sbjct: 201 TMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLSQIL 260

Query: 226 VKSIR 230
           V  I+
Sbjct: 261 VNQIK 265


>gi|68800005 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  124 bits (310), Expect = 9e-29
 Identities = 74/231 (32%), Positives = 119/231 (51%), Gaps = 12/231 (5%)

Query: 7   MKCVKFLLYVLLLAFCACAVGLIAVGVG-AQLVLSQTIIQGATPGSLLPVVIIAVGVFLF 65
           ++ VK+L++   L F     G++ VG+  A    S   +  + P      ++I  G F+ 
Sbjct: 6   LQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVM 65

Query: 66  LVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMEN 125
            + FVGC GA KEN CL++TF + L L+ L+E   AI  + + DK+      + ++ +  
Sbjct: 66  AIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHL 125

Query: 126 YPKNNHT--ASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGINFNE 183
           Y    +    +    +Q DF+CCG +NYTDW ++   +  RVPDSCC+  +  CG++   
Sbjct: 126 YGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFEV--YNATRVPDSCCLEFSESCGLH-AP 182

Query: 184 KAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFV--LGIVFA----CCLVKS 228
               K  C E +  WL++N+L V    L  A V  LG+ FA    C +VK+
Sbjct: 183 GTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVVKA 233


>gi|4507543 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  124 bits (310), Expect = 9e-29
 Identities = 74/231 (32%), Positives = 119/231 (51%), Gaps = 12/231 (5%)

Query: 7   MKCVKFLLYVLLLAFCACAVGLIAVGVG-AQLVLSQTIIQGATPGSLLPVVIIAVGVFLF 65
           ++ VK+L++   L F     G++ VG+  A    S   +  + P      ++I  G F+ 
Sbjct: 6   LQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVM 65

Query: 66  LVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMEN 125
            + FVGC GA KEN CL++TF + L L+ L+E   AI  + + DK+      + ++ +  
Sbjct: 66  AIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHL 125

Query: 126 YPKNNHT--ASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGINFNE 183
           Y    +    +    +Q DF+CCG +NYTDW ++   +  RVPDSCC+  +  CG++   
Sbjct: 126 YGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFEV--YNATRVPDSCCLEFSESCGLH-AP 182

Query: 184 KAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFV--LGIVFA----CCLVKS 228
               K  C E +  WL++N+L V    L  A V  LG+ FA    C +VK+
Sbjct: 183 GTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVVKA 233


>gi|68800018 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  124 bits (310), Expect = 9e-29
 Identities = 74/231 (32%), Positives = 119/231 (51%), Gaps = 12/231 (5%)

Query: 7   MKCVKFLLYVLLLAFCACAVGLIAVGVG-AQLVLSQTIIQGATPGSLLPVVIIAVGVFLF 65
           ++ VK+L++   L F     G++ VG+  A    S   +  + P      ++I  G F+ 
Sbjct: 6   LQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVM 65

Query: 66  LVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMEN 125
            + FVGC GA KEN CL++TF + L L+ L+E   AI  + + DK+      + ++ +  
Sbjct: 66  AIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHL 125

Query: 126 YPKNNHT--ASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGINFNE 183
           Y    +    +    +Q DF+CCG +NYTDW ++   +  RVPDSCC+  +  CG++   
Sbjct: 126 YGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFEV--YNATRVPDSCCLEFSESCGLH-AP 182

Query: 184 KAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFV--LGIVFA----CCLVKS 228
               K  C E +  WL++N+L V    L  A V  LG+ FA    C +VK+
Sbjct: 183 GTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVVKA 233


>gi|68800024 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  124 bits (310), Expect = 9e-29
 Identities = 74/231 (32%), Positives = 119/231 (51%), Gaps = 12/231 (5%)

Query: 7   MKCVKFLLYVLLLAFCACAVGLIAVGVG-AQLVLSQTIIQGATPGSLLPVVIIAVGVFLF 65
           ++ VK+L++   L F     G++ VG+  A    S   +  + P      ++I  G F+ 
Sbjct: 6   LQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVM 65

Query: 66  LVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMEN 125
            + FVGC GA KEN CL++TF + L L+ L+E   AI  + + DK+      + ++ +  
Sbjct: 66  AIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHL 125

Query: 126 YPKNNHT--ASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGINFNE 183
           Y    +    +    +Q DF+CCG +NYTDW ++   +  RVPDSCC+  +  CG++   
Sbjct: 126 YGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFEV--YNATRVPDSCCLEFSESCGLH-AP 182

Query: 184 KAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFV--LGIVFA----CCLVKS 228
               K  C E +  WL++N+L V    L  A V  LG+ FA    C +VK+
Sbjct: 183 GTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVVKA 233


>gi|68800011 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  124 bits (310), Expect = 9e-29
 Identities = 74/231 (32%), Positives = 119/231 (51%), Gaps = 12/231 (5%)

Query: 7   MKCVKFLLYVLLLAFCACAVGLIAVGVG-AQLVLSQTIIQGATPGSLLPVVIIAVGVFLF 65
           ++ VK+L++   L F     G++ VG+  A    S   +  + P      ++I  G F+ 
Sbjct: 6   LQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVM 65

Query: 66  LVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMEN 125
            + FVGC GA KEN CL++TF + L L+ L+E   AI  + + DK+      + ++ +  
Sbjct: 66  AIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHL 125

Query: 126 YPKNNHT--ASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGINFNE 183
           Y    +    +    +Q DF+CCG +NYTDW ++   +  RVPDSCC+  +  CG++   
Sbjct: 126 YGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFEV--YNATRVPDSCCLEFSESCGLH-AP 182

Query: 184 KAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFV--LGIVFA----CCLVKS 228
               K  C E +  WL++N+L V    L  A V  LG+ FA    C +VK+
Sbjct: 183 GTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVVKA 233


>gi|68799997 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  124 bits (310), Expect = 9e-29
 Identities = 74/231 (32%), Positives = 119/231 (51%), Gaps = 12/231 (5%)

Query: 7   MKCVKFLLYVLLLAFCACAVGLIAVGVG-AQLVLSQTIIQGATPGSLLPVVIIAVGVFLF 65
           ++ VK+L++   L F     G++ VG+  A    S   +  + P      ++I  G F+ 
Sbjct: 6   LQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVM 65

Query: 66  LVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMEN 125
            + FVGC GA KEN CL++TF + L L+ L+E   AI  + + DK+      + ++ +  
Sbjct: 66  AIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHL 125

Query: 126 YPKNNHT--ASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGINFNE 183
           Y    +    +    +Q DF+CCG +NYTDW ++   +  RVPDSCC+  +  CG++   
Sbjct: 126 YGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFEV--YNATRVPDSCCLEFSESCGLH-AP 182

Query: 184 KAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFV--LGIVFA----CCLVKS 228
               K  C E +  WL++N+L V    L  A V  LG+ FA    C +VK+
Sbjct: 183 GTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVVKA 233


>gi|87159824 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  120 bits (301), Expect = 1e-27
 Identities = 74/239 (30%), Positives = 122/239 (51%), Gaps = 15/239 (6%)

Query: 6   GMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPV--VIIAVGVF 63
           G  C+K+LL+     F    + ++AVG+   L L    I     G+ L    +++  G  
Sbjct: 12  GTVCLKYLLFTYNCCFWLAGLAVMAVGIWT-LALKSDYISLLASGTYLATAYILVVAGTV 70

Query: 64  LFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQM 123
           + +   +GCC   KE   L+  + I L +I L+E+ A I  Y +  ++ +E   N +  M
Sbjct: 71  VMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTM 130

Query: 124 -ENYPKNNHTA--SILDRMQADFKCCGAANYTDW---EKIPSMSKNR--VPDSCCINVTV 175
            + Y +  H A  S +D++Q +F CCG+ N  DW   E I S       VPDSCC  V  
Sbjct: 131 TKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVA 190

Query: 176 GCGINFNEKAIHK--EGCVEKIGGWLRKNVLVVAAAALGIAF--VLGIVFACCLVKSIR 230
            CG   +   I+K   GC+ K+  ++++++ V+ A  +GIA   V G++F CCL +S++
Sbjct: 191 LCGQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRSLK 249


>gi|87159822 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  120 bits (301), Expect = 1e-27
 Identities = 74/239 (30%), Positives = 122/239 (51%), Gaps = 15/239 (6%)

Query: 6   GMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPV--VIIAVGVF 63
           G  C+K+LL+     F    + ++AVG+   L L    I     G+ L    +++  G  
Sbjct: 12  GTVCLKYLLFTYNCCFWLAGLAVMAVGIWT-LALKSDYISLLASGTYLATAYILVVAGTV 70

Query: 64  LFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQM 123
           + +   +GCC   KE   L+  + I L +I L+E+ A I  Y +  ++ +E   N +  M
Sbjct: 71  VMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTM 130

Query: 124 -ENYPKNNHTA--SILDRMQADFKCCGAANYTDW---EKIPSMSKNR--VPDSCCINVTV 175
            + Y +  H A  S +D++Q +F CCG+ N  DW   E I S       VPDSCC  V  
Sbjct: 131 TKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVA 190

Query: 176 GCGINFNEKAIHK--EGCVEKIGGWLRKNVLVVAAAALGIAF--VLGIVFACCLVKSIR 230
            CG   +   I+K   GC+ K+  ++++++ V+ A  +GIA   V G++F CCL +S++
Sbjct: 191 LCGQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRSLK 249


>gi|21237751 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  120 bits (301), Expect = 1e-27
 Identities = 74/239 (30%), Positives = 122/239 (51%), Gaps = 15/239 (6%)

Query: 6   GMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPV--VIIAVGVF 63
           G  C+K+LL+     F    + ++AVG+   L L    I     G+ L    +++  G  
Sbjct: 12  GTVCLKYLLFTYNCCFWLAGLAVMAVGIWT-LALKSDYISLLASGTYLATAYILVVAGTV 70

Query: 64  LFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQM 123
           + +   +GCC   KE   L+  + I L +I L+E+ A I  Y +  ++ +E   N +  M
Sbjct: 71  VMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTM 130

Query: 124 -ENYPKNNHTA--SILDRMQADFKCCGAANYTDW---EKIPSMSKNR--VPDSCCINVTV 175
            + Y +  H A  S +D++Q +F CCG+ N  DW   E I S       VPDSCC  V  
Sbjct: 131 TKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVA 190

Query: 176 GCGINFNEKAIHK--EGCVEKIGGWLRKNVLVVAAAALGIAF--VLGIVFACCLVKSIR 230
            CG   +   I+K   GC+ K+  ++++++ V+ A  +GIA   V G++F CCL +S++
Sbjct: 191 LCGQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRSLK 249


>gi|21237748 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  120 bits (301), Expect = 1e-27
 Identities = 74/239 (30%), Positives = 122/239 (51%), Gaps = 15/239 (6%)

Query: 6   GMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPV--VIIAVGVF 63
           G  C+K+LL+     F    + ++AVG+   L L    I     G+ L    +++  G  
Sbjct: 12  GTVCLKYLLFTYNCCFWLAGLAVMAVGIWT-LALKSDYISLLASGTYLATAYILVVAGTV 70

Query: 64  LFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQM 123
           + +   +GCC   KE   L+  + I L +I L+E+ A I  Y +  ++ +E   N +  M
Sbjct: 71  VMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTM 130

Query: 124 -ENYPKNNHTA--SILDRMQADFKCCGAANYTDW---EKIPSMSKNR--VPDSCCINVTV 175
            + Y +  H A  S +D++Q +F CCG+ N  DW   E I S       VPDSCC  V  
Sbjct: 131 TKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVA 190

Query: 176 GCGINFNEKAIHK--EGCVEKIGGWLRKNVLVVAAAALGIAF--VLGIVFACCLVKSIR 230
            CG   +   I+K   GC+ K+  ++++++ V+ A  +GIA   V G++F CCL +S++
Sbjct: 191 LCGQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRSLK 249


>gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens]
          Length = 245

 Score =  119 bits (299), Expect = 2e-27
 Identities = 68/232 (29%), Positives = 119/232 (51%), Gaps = 6/232 (2%)

Query: 9   CVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAVGVFLFLVA 68
           C K +L +    F    V L+AVG+  ++ L           + +P V+IA G  + L+ 
Sbjct: 16  CFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVPFVLIATGTVIILLG 75

Query: 69  FVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENY-P 127
             GC   C+ +  ++  +A+FL+L+ LVE+ AAI G+VFR ++ + F NN+ + ++ Y  
Sbjct: 76  TFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQYNS 135

Query: 128 KNNHTASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGINFNEKAIH 187
             ++ +  +D++Q    CCG  +Y DW      S+   P SCC      C    +   ++
Sbjct: 136 TGDYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCC--KLEDCTPQRDADKVN 193

Query: 188 KEGCVEKIGGWLRKNVLVVAAAALGIAF--VLGIVFACCLVKSIRSG-YEVM 236
            EGC  K+   +   + VVA  + G+A   ++GI  A CL ++I +  YE++
Sbjct: 194 NEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNNQYEIV 245


>gi|5032201 transmembrane 4 superfamily member 8 isoform 1 [Homo
           sapiens]
          Length = 253

 Score =  108 bits (270), Expect = 4e-24
 Identities = 66/197 (33%), Positives = 106/197 (53%), Gaps = 11/197 (5%)

Query: 51  SLLP-VVIIAVGVFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRD 109
           +L+P VVIIAVG  LF++  +GCC   +E+ C + TF I L L+ + EV   + GYV+R 
Sbjct: 50  TLIPAVVIIAVGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRA 109

Query: 110 KVMSEFNNNFRQQMENYPKNNHTAS--ILDRMQADFKCCGAANYTDWEKIPSMSKNR--- 164
           KV +E + + ++  + Y   N  A+   +D +Q    CCG  NY+DWE      + +   
Sbjct: 110 KVENEVDRSIQKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQS 169

Query: 165 VPDSCCINVTVGC-GINFNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFV--LGIVF 221
           VP SCC      C G   +   ++ EGC   +   L++ ++ V  AAL  A +  LG++ 
Sbjct: 170 VPLSCCRETASNCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLC 229

Query: 222 ACCLV--KSIRSGYEVM 236
           AC ++  +S    YE++
Sbjct: 230 ACIVLCRRSRDPAYELL 246


>gi|50511934 transmembrane 4 superfamily member 17 isoform b [Homo
           sapiens]
          Length = 329

 Score =  107 bits (267), Expect = 9e-24
 Identities = 75/250 (30%), Positives = 120/250 (48%), Gaps = 31/250 (12%)

Query: 9   CVKFLLYVLLLAFCACAVGLIAVGV---GAQLVLSQTIIQGATP-GSLLPV-VIIAVGVF 63
           C K+ L+   + F       +A+G+   G + VLS   I   T  G L PV + + VG  
Sbjct: 16  CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSN--ISALTDLGGLDPVWLFVVVGGV 73

Query: 64  LFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQM 123
           + ++ F GC GA +EN  L+  F++FL LI  +E+A  I  +VF+D +  + N      +
Sbjct: 74  MSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNV 133

Query: 124 ENYPKNNHTASILDRMQADFKCCGAANYTDW---------EKIPSMSKNRVPDSCCIN-- 172
           + Y  +    +++D  Q  + CCGA    DW         +  PS  +  VP SCC+   
Sbjct: 134 KAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDP 193

Query: 173 ----VTVGCGINFNEKA-------IHKEGCVEKIGGWLRKNVLVVAAAALGIAFVLGIVF 221
               +   CG +   K        IH +GCV +   WL+ N++VVA   +GIA +   +F
Sbjct: 194 AEDVLNTQCGYDVRLKLELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQ--IF 251

Query: 222 ACCLVKSIRS 231
             CL +++ S
Sbjct: 252 GICLAQNLVS 261


>gi|68800032 tetraspanin 4 isoform b [Homo sapiens]
          Length = 174

 Score =  107 bits (266), Expect = 1e-23
 Identities = 60/170 (35%), Positives = 92/170 (54%), Gaps = 11/170 (6%)

Query: 67  VAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENY 126
           + FVGC GA KEN CL++TF + L L+ L+E   AI  + + DK+      + ++ +  Y
Sbjct: 3   IGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLY 62

Query: 127 PKNNHT--ASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGINFNEK 184
               +    +    +Q DF+CCG +NYTDW ++   +  RVPDSCC+  +  CG++    
Sbjct: 63  GTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFEV--YNATRVPDSCCLEFSESCGLH-APG 119

Query: 185 AIHKEGCVEKIGGWLRKNVLVVAAAALGIAFV--LGIVFA----CCLVKS 228
              K  C E +  WL++N+L V    L  A V  LG+ FA    C +VK+
Sbjct: 120 TWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVVKA 169


>gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens]
          Length = 237

 Score =  106 bits (265), Expect = 2e-23
 Identities = 73/235 (31%), Positives = 122/235 (51%), Gaps = 21/235 (8%)

Query: 5   GGMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVL-SQTIIQGATPGSLLPV---VIIAV 60
           G   C+K+ ++     F  C + ++A+ +  ++   SQ I      GS   V   ++IAV
Sbjct: 3   GVSACIKYSMFTFNFLFWLCGILILALAIWVRVSNDSQAIFGSEDVGSSSYVAVDILIAV 62

Query: 61  GVFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFR---DKVMSEF-- 115
           G  + ++ F+GCCGA KE+ C+++ F I L LI+L++VA  I G VF+   D++++E   
Sbjct: 63  GAIIMILGFLGCCGAIKESRCMLLLFFIGLLLILLLQVATGILGAVFKSKSDRIVNETLY 122

Query: 116 -NNNFRQQMENYPKNNHTASILDRMQADFKCCGAAN-YTDWEKIPSMSKNRVPDSC-CIN 172
            N           K    A I+   Q +FKCCG  N   DW      +    P+ C C++
Sbjct: 123 ENTKLLSATGESEKQFQEAIIV--FQEEFKCCGLVNGAADW----GNNFQHYPELCACLD 176

Query: 173 VTVGCGINFNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAF--VLGIVFACCL 225
               C  ++N K ++KE C+  I  +L KN+++V   + G+A   +LG+VF+  L
Sbjct: 177 KQRPCQ-SYNGKQVYKETCISFIKDFLAKNLIIVIGISFGLAVIEILGLVFSMVL 230


>gi|54859560 transmembrane 4 superfamily member 17 isoform a [Homo
           sapiens]
          Length = 332

 Score =  106 bits (264), Expect = 2e-23
 Identities = 75/253 (29%), Positives = 120/253 (47%), Gaps = 34/253 (13%)

Query: 9   CVKFLLYVLLLAFCACAVGLIAVGV---GAQLVLSQTIIQGATP-GSLLPV-VIIAVGVF 63
           C K+ L+   + F       +A+G+   G + VLS   I   T  G L PV + + VG  
Sbjct: 16  CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSN--ISALTDLGGLDPVWLFVVVGGV 73

Query: 64  LFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQM 123
           + ++ F GC GA +EN  L+  F++FL LI  +E+A  I  +VF+D +  + N      +
Sbjct: 74  MSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNV 133

Query: 124 ENYPKNNHTASILDRMQADFKCCGAANYTDW---------EKIPSMSKNRVPDSCCIN-- 172
           + Y  +    +++D  Q  + CCGA    DW         +  PS  +  VP SCC+   
Sbjct: 134 KAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDP 193

Query: 173 ----VTVGCGINFNEKA----------IHKEGCVEKIGGWLRKNVLVVAAAALGIAFVLG 218
               +   CG +   K           IH +GCV +   WL+ N++VVA   +GIA +  
Sbjct: 194 AEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQ- 252

Query: 219 IVFACCLVKSIRS 231
            +F  CL +++ S
Sbjct: 253 -IFGICLAQNLVS 264


>gi|54859505 transmembrane 4 superfamily member 17 isoform c [Homo
           sapiens]
          Length = 266

 Score =  105 bits (263), Expect = 3e-23
 Identities = 74/251 (29%), Positives = 119/251 (47%), Gaps = 34/251 (13%)

Query: 9   CVKFLLYVLLLAFCACAVGLIAVGV---GAQLVLSQTIIQGATP-GSLLPV-VIIAVGVF 63
           C K+ L+   + F       +A+G+   G + VLS   I   T  G L PV + + VG  
Sbjct: 16  CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSN--ISALTDLGGLDPVWLFVVVGGV 73

Query: 64  LFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQM 123
           + ++ F GC GA +EN  L+  F++FL LI  +E+A  I  +VF+D +  + N      +
Sbjct: 74  MSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNV 133

Query: 124 ENYPKNNHTASILDRMQADFKCCGAANYTDW---------EKIPSMSKNRVPDSCCIN-- 172
           + Y  +    +++D  Q  + CCGA    DW         +  PS  +  VP SCC+   
Sbjct: 134 KAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDP 193

Query: 173 ----VTVGCGINFNEKA----------IHKEGCVEKIGGWLRKNVLVVAAAALGIAFVLG 218
               +   CG +   K           IH +GCV +   WL+ N++VVA   +GIA +  
Sbjct: 194 AEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQ- 252

Query: 219 IVFACCLVKSI 229
            +F  CL +++
Sbjct: 253 -IFGICLAQNL 262


>gi|190194420 tetraspanin 14 isoform 1 [Homo sapiens]
          Length = 270

 Score =  105 bits (262), Expect = 3e-23
 Identities = 70/248 (28%), Positives = 117/248 (47%), Gaps = 27/248 (10%)

Query: 11  KFLLYVLLLAFCACAVGLIAVGVGA---QLVLSQTIIQGATPGSLLPVVIIAVGVFLFLV 67
           K+LL+   + F    V  + VG+ A   + VLS         G    V+++ VGV +F +
Sbjct: 16  KYLLFSYNIIFWLAGVVFLGVGLWAWSEKGVLSDLTKVTRMHGIDPVVLVLMVGVVMFTL 75

Query: 68  AFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYP 127
            F GC GA +EN CL+  F   + LI  +E+A A+  ++F+D V   F   F   +++Y 
Sbjct: 76  GFAGCVGALRENICLLNFFCGTIVLIFFLELAVAVLAFLFQDWVRDRFREFFESNIKSYR 135

Query: 128 KNNHTASILDRMQADFKCCGAANYTDWE---------KIPSMSKNRVPDSCCIN------ 172
            +    +++D +Q   +CCGA    DW+            S  K  VP SCC+       
Sbjct: 136 DDIDLQNLIDSLQKANQCCGAYGPEDWDLNVYFNCSGASYSREKCGVPFSCCVPDPAQKV 195

Query: 173 VTVGCGINFN-------EKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAF--VLGIVFAC 223
           V   CG +         +++I  +GC++ +  WL +N+ +VA   + I+   + GI  A 
Sbjct: 196 VNTQCGYDVRIQLKSKWDESIFTKGCIQALESWLPRNIYIVAGVFIAISLLQIFGIFLAR 255

Query: 224 CLVKSIRS 231
            L+  I +
Sbjct: 256 TLISDIEA 263


>gi|122937466 tetraspanin 11 [Homo sapiens]
          Length = 253

 Score =  102 bits (253), Expect = 4e-22
 Identities = 64/229 (27%), Positives = 114/229 (49%), Gaps = 13/229 (5%)

Query: 10  VKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTI-IQGATPGSLLPVVIIAVGVFLFLVA 68
           +K+LL+V    F      ++AVG+   +  S  + +  ++  +    ++I  GV + +  
Sbjct: 16  LKYLLFVFNFFFWVGGAAVLAVGIWTLVEKSGYLSVLASSTFAASAYILIFAGVLVMVTG 75

Query: 69  FVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQM-ENY- 126
           F+G      E    + T+   L +I LVE+ A +  +V+  ++  E   +  + + ENY 
Sbjct: 76  FLGFGAILWERKGCLSTYFCLLLVIFLVELVAGVLAHVYYQRLSDELKQHLNRTLAENYG 135

Query: 127 -PKNNHTASILDRMQADFKCCGAANYTDWEK-----IPSMSKNRVPDSCCINVTVGCGIN 180
            P      + +DR+Q DFKCCG+ +  DW+      +      +VPDSCC  V V CG  
Sbjct: 136 QPGATQITASVDRLQQDFKCCGSNSSADWQHSTYILLREAEGRQVPDSCCKTVVVRCGQR 195

Query: 181 FNEKAIHK--EGCVEKIGGWLRKNVLVVAAAALGIAF--VLGIVFACCL 225
            +   I+K   GC+ K+  +L  ++L++ A  +G+A   + G+V  CCL
Sbjct: 196 AHPSNIYKVEGGCLTKLEQFLADHLLLMGAVGIGVACLQICGMVLTCCL 244


>gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens]
          Length = 268

 Score =  101 bits (252), Expect = 5e-22
 Identities = 72/259 (27%), Positives = 123/259 (47%), Gaps = 39/259 (15%)

Query: 9   CVKFLLYVLLLAFCACAVGLIAVGVGA---QLVLSQTIIQGATP-GSLLPV-VIIAVGVF 63
           C+K+ ++   + F    +  + +G+ A   + VLS   I   T  G   PV + + VG  
Sbjct: 14  CIKYFIFGFNVIFWFLGITFLGIGLWAWNEKGVLSN--ISSITDLGGFDPVWLFLVVGGV 71

Query: 64  LFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSE----FNNNF 119
           +F++ F GC GA +EN  L+  F++FL +I  +E+ A +  +VF+D +  +     NNN 
Sbjct: 72  MFILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVFKDWIKDQLYFFINNNI 131

Query: 120 RQQMENYPKNNHTASILDRMQADFKCCGAANYTDW---------EKIPSMSKNRVPDSCC 170
           R   ++    N    ++D  Q  ++CCGA    DW         +   S  +  VP SCC
Sbjct: 132 RAYRDDIDLQN----LIDFTQEYWQCCGAFGADDWNLNIYFNCTDSNASRERCGVPFSCC 187

Query: 171 IN------VTVGCGINFNEK-------AIHKEGCVEKIGGWLRKNVLVVAAAALGIAFVL 217
                   +   CG +  +K        I+ +GCV +   WL+ N+ +VA   +GIA + 
Sbjct: 188 TKDPAEDVINTQCGYDARQKPEVDQQIVIYTKGCVPQFEKWLQDNLTIVAGIFIGIALLQ 247

Query: 218 GIVFACCLVKSIRSGYEVM 236
             +F  CL +++ S  E +
Sbjct: 248 --IFGICLAQNLVSDIEAV 264


>gi|42476204 tetraspanin 18 isoform 2 [Homo sapiens]
          Length = 248

 Score = 97.8 bits (242), Expect = 7e-21
 Identities = 65/245 (26%), Positives = 122/245 (49%), Gaps = 23/245 (9%)

Query: 7   MKCVKFLLYVLLLAFCACAVGLIAVGVGAQL-VLSQTIIQGATPGSLLPV-VIIAVGVFL 64
           + C+K+L++V           L+A+G+   +       I  A P  L    +++A+G  L
Sbjct: 6   LSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLAMGGLL 65

Query: 65  FLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQME 124
           FL+ F+GCCGA +EN CL++ F +F+ +I L E++AAI  ++FR+ +  EF    ++  +
Sbjct: 66  FLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFT--KELTK 123

Query: 125 NYPKNNHT---ASILDRMQADFKCCGAANYTDWE-----KIPSMSKNRVPDSCCINVTVG 176
           +Y  NN T   ++  + +   F CCG     D++     ++ ++    VP++CC      
Sbjct: 124 HYQGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRREPQS 183

Query: 177 -CGINFNEKA--------IHKEGCVEKIGGWLRKNVLVVAAAALGIAFV--LGIVFACCL 225
             G+  + +         ++K+GC   I       V +  A A+G+  +    ++FA CL
Sbjct: 184 RDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFAMCL 243

Query: 226 VKSIR 230
            + I+
Sbjct: 244 FRGIQ 248


>gi|6912530 transmembrane 4 superfamily member 15 [Homo sapiens]
          Length = 294

 Score = 96.7 bits (239), Expect = 2e-20
 Identities = 60/224 (26%), Positives = 103/224 (45%), Gaps = 22/224 (9%)

Query: 10  VKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLP-VVIIAVGVFLFLVA 68
           +KF L +    F    +G + + VG    + +   +      L P +++I +GV +F+V+
Sbjct: 20  LKFSLIIYSTVFWL--IGALVLSVGIYAEVERQKYKTLESAFLAPAIILILLGVVMFMVS 77

Query: 69  FVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYPK 128
           F+G   + ++N  L+  F   L + +++E+   +    FR++ +   N+N R+ +ENY  
Sbjct: 78  FIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYYD 137

Query: 129 NNHTASILDRMQADFKCCGAANYTDWEK-------IPSMSKNRVPDSCCIN-----VTVG 176
           +    +I+D +Q  FKCCG  +Y DW K        P      VP +CCI      V   
Sbjct: 138 DLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTEVVNTM 197

Query: 177 CGINFNEK-------AIHKEGCVEKIGGWLRKNVLVVAAAALGI 213
           CG    +K        I+  GC   +  W   N  ++A   LGI
Sbjct: 198 CGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGI 241


>gi|10834972 CD53 antigen [Homo sapiens]
          Length = 219

 Score = 95.5 bits (236), Expect = 4e-20
 Identities = 62/221 (28%), Positives = 99/221 (44%), Gaps = 22/221 (9%)

Query: 7   MKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAVGVFLFL 66
           +K +K++L+   L F  C   ++  G+   +  +  ++    P   L  V + VG  + +
Sbjct: 6   LKLLKYVLFFFNLLFWICGCCILGFGIYLLIHNNFGVLFHNLPSLTLGNVFVIVGSIIMV 65

Query: 67  VAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENY 126
           VAF+GC G+ KEN CL+++F I L +I+L EV  AI  +V+  K+           +  Y
Sbjct: 66  VAFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKGLTDSIHRY 125

Query: 127 PKNNHTASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGINFNEKAI 186
             +N T +  D +Q+  +CCG    +DW   P       P SC  +  V           
Sbjct: 126 HSDNSTKAAWDSIQSFLQCCGINGTSDWTSGP-------PASCPSDRKV----------- 167

Query: 187 HKEGCVEKIGGWLRKNVLVVAAAALGIAF--VLGIVFACCL 225
             EGC  K   W   N L +    + +    VLG+ FA  L
Sbjct: 168 --EGCYAKARLWFHSNFLYIGIITICVCVIEVLGMSFALTL 206


>gi|91106727 CD53 antigen [Homo sapiens]
          Length = 219

 Score = 95.5 bits (236), Expect = 4e-20
 Identities = 62/221 (28%), Positives = 99/221 (44%), Gaps = 22/221 (9%)

Query: 7   MKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAVGVFLFL 66
           +K +K++L+   L F  C   ++  G+   +  +  ++    P   L  V + VG  + +
Sbjct: 6   LKLLKYVLFFFNLLFWICGCCILGFGIYLLIHNNFGVLFHNLPSLTLGNVFVIVGSIIMV 65

Query: 67  VAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENY 126
           VAF+GC G+ KEN CL+++F I L +I+L EV  AI  +V+  K+           +  Y
Sbjct: 66  VAFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKGLTDSIHRY 125

Query: 127 PKNNHTASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGINFNEKAI 186
             +N T +  D +Q+  +CCG    +DW   P       P SC  +  V           
Sbjct: 126 HSDNSTKAAWDSIQSFLQCCGINGTSDWTSGP-------PASCPSDRKV----------- 167

Query: 187 HKEGCVEKIGGWLRKNVLVVAAAALGIAF--VLGIVFACCL 225
             EGC  K   W   N L +    + +    VLG+ FA  L
Sbjct: 168 --EGCYAKARLWFHSNFLYIGIITICVCVIEVLGMSFALTL 206


>gi|6912528 transmembrane 4 superfamily member 12 [Homo sapiens]
          Length = 305

 Score = 94.4 bits (233), Expect = 8e-20
 Identities = 70/247 (28%), Positives = 121/247 (48%), Gaps = 23/247 (9%)

Query: 1   MAVEGGMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLS-------QTIIQGATPGSLL 53
           MA E  +KC++ LLY L L F   ++ ++AV    +  L+       +T ++ A   +  
Sbjct: 1   MAREDSVKCLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYF 60

Query: 54  PVV---IIAVGVFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDK 110
           PVV   +IAV  FL +V  +G CG  K N  L+  +   L +I  VE+A  +  Y     
Sbjct: 61  PVVHPVMIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGVWTYEQELM 120

Query: 111 VMSEFNN--NFRQQMENY--PKNNHTASILDRMQADFKCCGAANYTDWEKIPSMSKNRVP 166
           V  ++++    + +M NY  P+        +  Q +FKCCG   +TDW ++  M  +  P
Sbjct: 121 VPVQWSDMVTLKARMTNYGLPRYRWLTHAWNFFQREFKCCGVVYFTDWLEMTEM--DWPP 178

Query: 167 DSCCINVTVGCGINFNEK---AIHKEGCVEKIGGWLR----KNVLVVAAAALGIAFVLGI 219
           DSCC+    GC    +++    +++EGC +K+  +LR      VL     ++G+  +L +
Sbjct: 179 DSCCVREFPGCSKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQILAM 238

Query: 220 VFACCLV 226
           +    L+
Sbjct: 239 ILTITLL 245


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.329    0.141    0.442 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,857,468
Number of Sequences: 37866
Number of extensions: 295243
Number of successful extensions: 1127
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 967
Number of HSP's gapped (non-prelim): 63
length of query: 236
length of database: 18,247,518
effective HSP length: 99
effective length of query: 137
effective length of database: 14,498,784
effective search space: 1986333408
effective search space used: 1986333408
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.