Guide to the Human Genome
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Search of human proteins with 8923415

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|8923415 membrane-associated ring finger (C3HC4) 5 [Homo
sapiens]
         (278 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|8923415 membrane-associated ring finger (C3HC4) 5 [Homo sapiens]   572   e-163
gi|156523244 membrane-associated ring finger (C3HC4) 11 [Homo sa...    48   8e-06
gi|50539414 cellular modulator of immune recognition isoform 7 [...    45   5e-05
gi|50539412 cellular modulator of immune recognition isoform 6 [...    45   5e-05
gi|50539410 cellular modulator of immune recognition isoform 8 [...    45   5e-05
gi|8923613 membrane-associated RING-CH protein I [Homo sapiens]        44   2e-04
gi|40255016 membrane-associated RING-CH protein IX [Homo sapiens]      44   2e-04
gi|57977325 membrane-associated ring finger (C3HC4) 4 [Homo sapi...    43   3e-04
gi|12383066 axotrophin [Homo sapiens]                                  40   0.003
gi|154937342 ring finger protein 190 [Homo sapiens]                    35   0.055
gi|154937340 ring finger protein 190 [Homo sapiens]                    35   0.055
gi|33589846 membrane-associated ring finger (C3HC4) 6 [Homo sapi...    35   0.094
gi|53729334 membrane-associated ring finger (C3HC4) 2 isoform 2 ...    33   0.27 
gi|53729332 membrane-associated ring finger (C3HC4) 2 isoform 1 ...    33   0.27 
gi|53729330 membrane-associated ring finger (C3HC4) 2 isoform 1 ...    33   0.27 
gi|30425370 membrane-associated ring finger (C3HC4) 3 [Homo sapi...    32   0.47 
gi|27477134 nucleoporin 210 [Homo sapiens]                             32   0.47 
gi|89363020 nuclear transcription factor, X-box binding-like 1 [...    30   3.0  
gi|238550100 transmembrane channel-like 7 isoform b [Homo sapiens]     28   8.8  
gi|238550098 transmembrane channel-like 7 isoform a [Homo sapiens]     28   8.8  

>gi|8923415 membrane-associated ring finger (C3HC4) 5 [Homo sapiens]
          Length = 278

 Score =  572 bits (1473), Expect = e-163
 Identities = 278/278 (100%), Positives = 278/278 (100%)

Query: 1   MPDQALQQMLDRSCWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQRGNST 60
           MPDQALQQMLDRSCWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQRGNST
Sbjct: 1   MPDQALQQMLDRSCWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQRGNST 60

Query: 61  ARVACPQCNAEYLIVFPKLGPVVYVLDLADRLISKACPFAAAGIMVGSIYWTAVTYGAVT 120
           ARVACPQCNAEYLIVFPKLGPVVYVLDLADRLISKACPFAAAGIMVGSIYWTAVTYGAVT
Sbjct: 61  ARVACPQCNAEYLIVFPKLGPVVYVLDLADRLISKACPFAAAGIMVGSIYWTAVTYGAVT 120

Query: 121 VMQVVGHKEGLDVMERADPLFLLIGLPTIPVMLILGKMIRWEDYVLRLWRKYSNKLQILN 180
           VMQVVGHKEGLDVMERADPLFLLIGLPTIPVMLILGKMIRWEDYVLRLWRKYSNKLQILN
Sbjct: 121 VMQVVGHKEGLDVMERADPLFLLIGLPTIPVMLILGKMIRWEDYVLRLWRKYSNKLQILN 180

Query: 181 SIFPGIGCPVPRIPAEANPLADHVSATRILCGALVFPTIATIVGKLMFSSVNSNLQRTIL 240
           SIFPGIGCPVPRIPAEANPLADHVSATRILCGALVFPTIATIVGKLMFSSVNSNLQRTIL
Sbjct: 181 SIFPGIGCPVPRIPAEANPLADHVSATRILCGALVFPTIATIVGKLMFSSVNSNLQRTIL 240

Query: 241 GGIAFVAIKGAFKVYFKQQQYLRQAHRKILNYPEQEEA 278
           GGIAFVAIKGAFKVYFKQQQYLRQAHRKILNYPEQEEA
Sbjct: 241 GGIAFVAIKGAFKVYFKQQQYLRQAHRKILNYPEQEEA 278


>gi|156523244 membrane-associated ring finger (C3HC4) 11 [Homo
           sapiens]
          Length = 402

 Score = 48.1 bits (113), Expect = 8e-06
 Identities = 30/100 (30%), Positives = 48/100 (48%), Gaps = 12/100 (12%)

Query: 14  CWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQRGNSTARVACPQCNAEYL 73
           C +CF   E     E + PCRC GS ++ HQ CL +W+ E  RG+ T    C  C   Y 
Sbjct: 170 CKICFQGAEQ---GELLNPCRCDGSVRYTHQLCLLKWISE--RGSWT----CELCCYRYH 220

Query: 74  IVFPKLGPVVYVLDLADRLISKACPFAAAGIMVGSIYWTA 113
           ++  K+        ++  L+ K    A   +++GS++  A
Sbjct: 221 VIAIKMKQPCQWQSISITLVEKVQMIA---VILGSLFLIA 257


>gi|50539414 cellular modulator of immune recognition isoform 7
           [Homo sapiens]
          Length = 291

 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 9/69 (13%)

Query: 14  CWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQRGNSTARVACPQCNAEYL 73
           C +C    +D+  +  + PC C GS  +VHQACLQ+W+       S+    C  C  E+ 
Sbjct: 80  CRICHCEGDDE--SPLITPCHCTGSLHFVHQACLQQWI------KSSDTRCCELCKYEF- 130

Query: 74  IVFPKLGPV 82
           I+  KL P+
Sbjct: 131 IMETKLKPL 139


>gi|50539412 cellular modulator of immune recognition isoform 6
           [Homo sapiens]
          Length = 291

 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 9/69 (13%)

Query: 14  CWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQRGNSTARVACPQCNAEYL 73
           C +C    +D+  +  + PC C GS  +VHQACLQ+W+       S+    C  C  E+ 
Sbjct: 80  CRICHCEGDDE--SPLITPCHCTGSLHFVHQACLQQWI------KSSDTRCCELCKYEF- 130

Query: 74  IVFPKLGPV 82
           I+  KL P+
Sbjct: 131 IMETKLKPL 139


>gi|50539410 cellular modulator of immune recognition isoform 8
           [Homo sapiens]
          Length = 291

 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 9/69 (13%)

Query: 14  CWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQRGNSTARVACPQCNAEYL 73
           C +C    +D+  +  + PC C GS  +VHQACLQ+W+       S+    C  C  E+ 
Sbjct: 80  CRICHCEGDDE--SPLITPCHCTGSLHFVHQACLQQWI------KSSDTRCCELCKYEF- 130

Query: 74  IVFPKLGPV 82
           I+  KL P+
Sbjct: 131 IMETKLKPL 139


>gi|8923613 membrane-associated RING-CH protein I [Homo sapiens]
          Length = 272

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 9/69 (13%)

Query: 14  CWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQRGNSTARVACPQCNAEYL 73
           C +C    E D  +  + PCRC G+ ++VHQ+CL +W+       S+    C  C  ++ 
Sbjct: 63  CRICHC--EGDEESPLITPCRCTGTLRFVHQSCLHQWI------KSSDTRCCELCKYDF- 113

Query: 74  IVFPKLGPV 82
           I+  KL P+
Sbjct: 114 IMETKLKPL 122


>gi|40255016 membrane-associated RING-CH protein IX [Homo sapiens]
          Length = 346

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 21/62 (33%), Positives = 30/62 (48%), Gaps = 9/62 (14%)

Query: 14  CWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQRGNSTARVACPQCNAEYL 73
           C +CF   E     E + PCRC GS +  HQ CL RW+ E+         +C  C  +Y 
Sbjct: 110 CRICFQGPEQ---GELLSPCRCDGSVRCTHQPCLIRWISER------GSWSCELCYFKYQ 160

Query: 74  IV 75
           ++
Sbjct: 161 VL 162


>gi|57977325 membrane-associated ring finger (C3HC4) 4 [Homo
           sapiens]
          Length = 410

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 18/41 (43%), Positives = 23/41 (56%), Gaps = 3/41 (7%)

Query: 14  CWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEK 54
           C +CF   E     E + PCRC GS K  HQ CL +W+ E+
Sbjct: 163 CRICFQGPEQ---GELLSPCRCDGSVKCTHQPCLIKWISER 200


>gi|12383066 axotrophin [Homo sapiens]
          Length = 704

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 15/41 (36%), Positives = 24/41 (58%), Gaps = 2/41 (4%)

Query: 30  VRPCRCRGSTKWVHQACLQRWVDEKQRGNST--ARVACPQC 68
           + PC+C GS ++VHQ C+++W+  K    S+  A   C  C
Sbjct: 567 IEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEAVTTCELC 607


>gi|154937342 ring finger protein 190 [Homo sapiens]
          Length = 808

 Score = 35.4 bits (80), Expect = 0.055
 Identities = 16/47 (34%), Positives = 24/47 (51%), Gaps = 2/47 (4%)

Query: 30  VRPCRCRGSTKWVHQACLQRWVDEKQRGNST--ARVACPQCNAEYLI 74
           + PC C GS ++VHQ CL++W+  K    +   A   C  C    L+
Sbjct: 674 LEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLV 720


>gi|154937340 ring finger protein 190 [Homo sapiens]
          Length = 808

 Score = 35.4 bits (80), Expect = 0.055
 Identities = 16/47 (34%), Positives = 24/47 (51%), Gaps = 2/47 (4%)

Query: 30  VRPCRCRGSTKWVHQACLQRWVDEKQRGNST--ARVACPQCNAEYLI 74
           + PC C GS ++VHQ CL++W+  K    +   A   C  C    L+
Sbjct: 674 LEPCGCVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLV 720


>gi|33589846 membrane-associated ring finger (C3HC4) 6 [Homo
          sapiens]
          Length = 910

 Score = 34.7 bits (78), Expect = 0.094
 Identities = 14/43 (32%), Positives = 23/43 (53%), Gaps = 2/43 (4%)

Query: 14 CWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQR 56
          C VC +    ++      PC C GS K++HQ CL +W+   ++
Sbjct: 9  CRVCRSEGTPEKPL--YHPCVCTGSIKFIHQECLVQWLKHSRK 49


>gi|53729334 membrane-associated ring finger (C3HC4) 2 isoform 2
           [Homo sapiens]
          Length = 176

 Score = 33.1 bits (74), Expect = 0.27
 Identities = 13/43 (30%), Positives = 24/43 (55%), Gaps = 6/43 (13%)

Query: 32  PCRCRGSTKWVHQACLQRWVDEKQRGNSTARVACPQCNAEYLI 74
           PC C G+   VH++CL++W+      +S+    C  C+ E+ +
Sbjct: 79  PCGCTGTLGAVHKSCLEKWL------SSSNTSYCELCHTEFAV 115


>gi|53729332 membrane-associated ring finger (C3HC4) 2 isoform 1
           [Homo sapiens]
          Length = 246

 Score = 33.1 bits (74), Expect = 0.27
 Identities = 13/43 (30%), Positives = 24/43 (55%), Gaps = 6/43 (13%)

Query: 32  PCRCRGSTKWVHQACLQRWVDEKQRGNSTARVACPQCNAEYLI 74
           PC C G+   VH++CL++W+      +S+    C  C+ E+ +
Sbjct: 79  PCGCTGTLGAVHKSCLEKWL------SSSNTSYCELCHTEFAV 115


>gi|53729330 membrane-associated ring finger (C3HC4) 2 isoform 1
           [Homo sapiens]
          Length = 246

 Score = 33.1 bits (74), Expect = 0.27
 Identities = 13/43 (30%), Positives = 24/43 (55%), Gaps = 6/43 (13%)

Query: 32  PCRCRGSTKWVHQACLQRWVDEKQRGNSTARVACPQCNAEYLI 74
           PC C G+   VH++CL++W+      +S+    C  C+ E+ +
Sbjct: 79  PCGCTGTLGAVHKSCLEKWL------SSSNTSYCELCHTEFAV 115


>gi|30425370 membrane-associated ring finger (C3HC4) 3 [Homo
           sapiens]
          Length = 253

 Score = 32.3 bits (72), Expect = 0.47
 Identities = 13/59 (22%), Positives = 27/59 (45%), Gaps = 6/59 (10%)

Query: 16  VCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQRGNSTARVACPQCNAEYLI 74
           +C    E     + + PC C G+   +H++CL+ W+      +S+    C  C+  + +
Sbjct: 70  MCRICHEGSSQEDLLSPCECTGTLGTIHRSCLEHWL------SSSNTSYCELCHFRFAV 122


>gi|27477134 nucleoporin 210 [Homo sapiens]
          Length = 1887

 Score = 32.3 bits (72), Expect = 0.47
 Identities = 25/102 (24%), Positives = 49/102 (48%), Gaps = 3/102 (2%)

Query: 176  LQILNSIFPGIG--CPVPRIPAEANPLADHVSATRILCGALVFPTIATIVGKLMFSSVNS 233
            L++ ++  PG+    P+P + A +  L+  +    +LC A V  ++  + G    SS NS
Sbjct: 1456 LRVWDAEHPGLSDFMPLPVLQAISPELSGAMVVGDVLCLATVLTSLEGLSGTWS-SSANS 1514

Query: 234  NLQRTILGGIAFVAIKGAFKVYFKQQQYLRQAHRKILNYPEQ 275
             L      G+A     G+  VY++   +LR     +++ P++
Sbjct: 1515 ILHIDPKTGVAVARAVGSVTVYYEVAGHLRTYKEVVVSVPQR 1556


>gi|89363020 nuclear transcription factor, X-box binding-like 1
           [Homo sapiens]
          Length = 911

 Score = 29.6 bits (65), Expect = 3.0
 Identities = 18/70 (25%), Positives = 28/70 (40%), Gaps = 15/70 (21%)

Query: 13  SCWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQ----------RGNSTAR 62
           +C +C A+ + ++ A W     C G     H  C+Q+W  + Q           G     
Sbjct: 159 TCLICIASVKRNQ-AVW----SCSGCFCIFHMPCIQKWAKDSQFLVSSVTDDDFGKKDCP 213

Query: 63  VACPQCNAEY 72
             CP+C  EY
Sbjct: 214 WPCPKCRFEY 223


>gi|238550100 transmembrane channel-like 7 isoform b [Homo sapiens]
          Length = 613

 Score = 28.1 bits (61), Expect = 8.8
 Identities = 38/147 (25%), Positives = 58/147 (39%), Gaps = 21/147 (14%)

Query: 91  RLISKACPFAAAGIMVGSIYWTAVTYGAVTVMQVVGHKEGLDVMERADPLFLLIGLPTIP 150
           RL       A  G    +IY         TV      K+ +D M   + LF+L  LP+I 
Sbjct: 252 RLFLNCIVLAVLGACFYAIY-------VATVFSQEHMKKEIDKMVFGENLFILY-LPSIV 303

Query: 151 VML-------ILGKMIRWEDYVLRLWRKYSNKLQILNSIFPGIGCPVPRIPAEANPLADH 203
           + L       I  K+IR+EDY       +  +L IL  +F  +      +    + +   
Sbjct: 304 ITLANFITPMIFAKIIRYEDYS----PGFEIRLTILRCVFMRLATICVLVFTLGSKITSC 359

Query: 204 VSATRILCG--ALVFPTIATIVGKLMF 228
              T  LCG    ++P   T VG+ M+
Sbjct: 360 DDDTCDLCGYNQKLYPCWETQVGQEMY 386


>gi|238550098 transmembrane channel-like 7 isoform a [Homo sapiens]
          Length = 723

 Score = 28.1 bits (61), Expect = 8.8
 Identities = 38/147 (25%), Positives = 58/147 (39%), Gaps = 21/147 (14%)

Query: 91  RLISKACPFAAAGIMVGSIYWTAVTYGAVTVMQVVGHKEGLDVMERADPLFLLIGLPTIP 150
           RL       A  G    +IY         TV      K+ +D M   + LF+L  LP+I 
Sbjct: 362 RLFLNCIVLAVLGACFYAIY-------VATVFSQEHMKKEIDKMVFGENLFILY-LPSIV 413

Query: 151 VML-------ILGKMIRWEDYVLRLWRKYSNKLQILNSIFPGIGCPVPRIPAEANPLADH 203
           + L       I  K+IR+EDY       +  +L IL  +F  +      +    + +   
Sbjct: 414 ITLANFITPMIFAKIIRYEDYS----PGFEIRLTILRCVFMRLATICVLVFTLGSKITSC 469

Query: 204 VSATRILCG--ALVFPTIATIVGKLMF 228
              T  LCG    ++P   T VG+ M+
Sbjct: 470 DDDTCDLCGYNQKLYPCWETQVGQEMY 496


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.139    0.445 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,326,046
Number of Sequences: 37866
Number of extensions: 415840
Number of successful extensions: 1327
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1311
Number of HSP's gapped (non-prelim): 20
length of query: 278
length of database: 18,247,518
effective HSP length: 101
effective length of query: 177
effective length of database: 14,423,052
effective search space: 2552880204
effective search space used: 2552880204
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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