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Search of human proteins with 14149793
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14149793 glutamine rich 2 [Homo sapiens]
(1663 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14149793 glutamine rich 2 [Homo sapiens] 3331 0.0
gi|61175248 spermidine/spermine N1-acetyl transferase-like 1 [Ho... 164 7e-40
gi|222446620 hypothetical protein LOC342346 [Homo sapiens] 107 1e-22
gi|150170670 piccolo isoform 2 [Homo sapiens] 95 6e-19
gi|150378539 piccolo isoform 1 [Homo sapiens] 95 6e-19
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 62 4e-09
gi|14149675 cleavage stimulation factor, 3' pre-RNA, subunit 2, ... 60 1e-08
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 59 5e-08
gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens] 57 1e-07
gi|21735548 centrosomal protein 2 [Homo sapiens] 56 3e-07
gi|21450705 leucine rich repeat containing 45 [Homo sapiens] 55 4e-07
gi|4557493 cleavage stimulation factor subunit 2 [Homo sapiens] 55 6e-07
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 54 1e-06
gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens] 54 1e-06
gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens] 54 1e-06
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 53 2e-06
gi|16262452 cingulin [Homo sapiens] 52 5e-06
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 52 6e-06
gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens] 52 6e-06
gi|33188443 microfilament and actin filament cross-linker protei... 51 8e-06
gi|33188445 microfilament and actin filament cross-linker protei... 51 8e-06
gi|58530840 desmoplakin isoform I [Homo sapiens] 51 1e-05
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr... 51 1e-05
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr... 51 1e-05
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 51 1e-05
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 51 1e-05
gi|55749708 outer dense fiber of sperm tails 2-like isoform b [H... 51 1e-05
gi|55749696 outer dense fiber of sperm tails 2-like isoform a [H... 51 1e-05
gi|156104908 myosin heavy chain 6 [Homo sapiens] 50 2e-05
gi|7705415 hook homolog 1 [Homo sapiens] 50 2e-05
>gi|14149793 glutamine rich 2 [Homo sapiens]
Length = 1663
Score = 3331 bits (8637), Expect = 0.0
Identities = 1663/1663 (100%), Positives = 1663/1663 (100%)
Query: 1 MKDAAEELSFARVLLQRVDELEKLFKDREQFLELVSRKLSLVPGAEEVTMVTWEELEQAI 60
MKDAAEELSFARVLLQRVDELEKLFKDREQFLELVSRKLSLVPGAEEVTMVTWEELEQAI
Sbjct: 1 MKDAAEELSFARVLLQRVDELEKLFKDREQFLELVSRKLSLVPGAEEVTMVTWEELEQAI 60
Query: 61 TDGWRASQAGSETLMGFSKHGGFTSLTSPEGTLSGDSTKQPSIEQALDSASGLGPDRTAS 120
TDGWRASQAGSETLMGFSKHGGFTSLTSPEGTLSGDSTKQPSIEQALDSASGLGPDRTAS
Sbjct: 61 TDGWRASQAGSETLMGFSKHGGFTSLTSPEGTLSGDSTKQPSIEQALDSASGLGPDRTAS 120
Query: 121 GSGGTAHPSDGVSSREQSKVPSGTGRQQQPRARDEAGVPRLHQSSTFQFKSDSDRHRSRE 180
GSGGTAHPSDGVSSREQSKVPSGTGRQQQPRARDEAGVPRLHQSSTFQFKSDSDRHRSRE
Sbjct: 121 GSGGTAHPSDGVSSREQSKVPSGTGRQQQPRARDEAGVPRLHQSSTFQFKSDSDRHRSRE 180
Query: 181 KLTSTQPRRNARPGPVQQDLPLARDQPSSVPASQSQVHLRPDRRGLEPTGMNQPGLVPAS 240
KLTSTQPRRNARPGPVQQDLPLARDQPSSVPASQSQVHLRPDRRGLEPTGMNQPGLVPAS
Sbjct: 181 KLTSTQPRRNARPGPVQQDLPLARDQPSSVPASQSQVHLRPDRRGLEPTGMNQPGLVPAS 240
Query: 241 TYPHGVVPLSMGQLGVPPPEMDDRELIPFVVDEQRMLPPSVPGRDQQGLELPSTDQHGLV 300
TYPHGVVPLSMGQLGVPPPEMDDRELIPFVVDEQRMLPPSVPGRDQQGLELPSTDQHGLV
Sbjct: 241 TYPHGVVPLSMGQLGVPPPEMDDRELIPFVVDEQRMLPPSVPGRDQQGLELPSTDQHGLV 300
Query: 301 SVSAYQHGMTFPGTDQRSMEPLGMDQRGCVISGMGQQGLVPPGIDQQGLTLPVVDQHGLV 360
SVSAYQHGMTFPGTDQRSMEPLGMDQRGCVISGMGQQGLVPPGIDQQGLTLPVVDQHGLV
Sbjct: 301 SVSAYQHGMTFPGTDQRSMEPLGMDQRGCVISGMGQQGLVPPGIDQQGLTLPVVDQHGLV 360
Query: 361 LPFTDQHGLVSPGLMPISADQQGFVQPSLEATGFIQPGTEQHDLIQSGRFQRALVQRGAY 420
LPFTDQHGLVSPGLMPISADQQGFVQPSLEATGFIQPGTEQHDLIQSGRFQRALVQRGAY
Sbjct: 361 LPFTDQHGLVSPGLMPISADQQGFVQPSLEATGFIQPGTEQHDLIQSGRFQRALVQRGAY 420
Query: 421 QPGLVQPGADQRGLVRPGMDQSGLAQPGADQRGLVWPGMDQSGLAQPGRDQHGLIQPGTG 480
QPGLVQPGADQRGLVRPGMDQSGLAQPGADQRGLVWPGMDQSGLAQPGRDQHGLIQPGTG
Sbjct: 421 QPGLVQPGADQRGLVRPGMDQSGLAQPGADQRGLVWPGMDQSGLAQPGRDQHGLIQPGTG 480
Query: 481 QHDLVQSGTGQGVLVQPGVDQPGMVQPGRFQRALVQPGAYQPGLVQPGADQIDVVQPGAD 540
QHDLVQSGTGQGVLVQPGVDQPGMVQPGRFQRALVQPGAYQPGLVQPGADQIDVVQPGAD
Sbjct: 481 QHDLVQSGTGQGVLVQPGVDQPGMVQPGRFQRALVQPGAYQPGLVQPGADQIDVVQPGAD 540
Query: 541 QHGLVQSGADQSDLAQPGAVQHGLVQPGVDQRGLAQPRADHQRGLVPPGADQRGLVQPGA 600
QHGLVQSGADQSDLAQPGAVQHGLVQPGVDQRGLAQPRADHQRGLVPPGADQRGLVQPGA
Sbjct: 541 QHGLVQSGADQSDLAQPGAVQHGLVQPGVDQRGLAQPRADHQRGLVPPGADQRGLVQPGA 600
Query: 601 DQHGLVQPGVDQHGLAQPGEVQRSLVQPGIVQRGLVQPGAVQRGLVQPGAVQRGLVQPGV 660
DQHGLVQPGVDQHGLAQPGEVQRSLVQPGIVQRGLVQPGAVQRGLVQPGAVQRGLVQPGV
Sbjct: 601 DQHGLVQPGVDQHGLAQPGEVQRSLVQPGIVQRGLVQPGAVQRGLVQPGAVQRGLVQPGV 660
Query: 661 DQRGLVQPGAVQRGLVQPGAVQHGLVQPGADQRGLVQPGVDQRGLVQPGVDQRGLVQPGM 720
DQRGLVQPGAVQRGLVQPGAVQHGLVQPGADQRGLVQPGVDQRGLVQPGVDQRGLVQPGM
Sbjct: 661 DQRGLVQPGAVQRGLVQPGAVQHGLVQPGADQRGLVQPGVDQRGLVQPGVDQRGLVQPGM 720
Query: 721 DQRGLIQPGADQPGLVQPGAGQLGMVQPGIGQQGMVQPQADPHGLVQPGAYPLGLVQPGA 780
DQRGLIQPGADQPGLVQPGAGQLGMVQPGIGQQGMVQPQADPHGLVQPGAYPLGLVQPGA
Sbjct: 721 DQRGLIQPGADQPGLVQPGAGQLGMVQPGIGQQGMVQPQADPHGLVQPGAYPLGLVQPGA 780
Query: 781 YLHDLSQSGTYPRGLVQPGMDQYGLRQPGAYQPGLIAPGTKLRGSSTFQADSTGFISVRP 840
YLHDLSQSGTYPRGLVQPGMDQYGLRQPGAYQPGLIAPGTKLRGSSTFQADSTGFISVRP
Sbjct: 781 YLHDLSQSGTYPRGLVQPGMDQYGLRQPGAYQPGLIAPGTKLRGSSTFQADSTGFISVRP 840
Query: 841 YQHGMVPPGREQYGQVSPLLASQGLASPGIDRRSLVPPETYQQGLMHPGTDQHSPIPLST 900
YQHGMVPPGREQYGQVSPLLASQGLASPGIDRRSLVPPETYQQGLMHPGTDQHSPIPLST
Sbjct: 841 YQHGMVPPGREQYGQVSPLLASQGLASPGIDRRSLVPPETYQQGLMHPGTDQHSPIPLST 900
Query: 901 GLGSTHPDQQHVASPGPGEHDQVYPDAAQHGHAFSLFDSHDSMYPGYRGPGYLSADQHGQ 960
GLGSTHPDQQHVASPGPGEHDQVYPDAAQHGHAFSLFDSHDSMYPGYRGPGYLSADQHGQ
Sbjct: 901 GLGSTHPDQQHVASPGPGEHDQVYPDAAQHGHAFSLFDSHDSMYPGYRGPGYLSADQHGQ 960
Query: 961 EGLDPNRTRASDRHGIPAQKAPGQDVTLFRSPDSVDRVLSEGSEVSSEVLSERRNSLRRM 1020
EGLDPNRTRASDRHGIPAQKAPGQDVTLFRSPDSVDRVLSEGSEVSSEVLSERRNSLRRM
Sbjct: 961 EGLDPNRTRASDRHGIPAQKAPGQDVTLFRSPDSVDRVLSEGSEVSSEVLSERRNSLRRM 1020
Query: 1021 SSSFPTAVETFHLMGELSSLYVGLKESMKDLDEEQAGQTDLEKIQFLLAQMVKRTIPPEL 1080
SSSFPTAVETFHLMGELSSLYVGLKESMKDLDEEQAGQTDLEKIQFLLAQMVKRTIPPEL
Sbjct: 1021 SSSFPTAVETFHLMGELSSLYVGLKESMKDLDEEQAGQTDLEKIQFLLAQMVKRTIPPEL 1080
Query: 1081 QEQLKTVKTLAKEVWQEKAKVERLQRILEGEGNQEAGKELKAGELRLQLGVLRVTVADIE 1140
QEQLKTVKTLAKEVWQEKAKVERLQRILEGEGNQEAGKELKAGELRLQLGVLRVTVADIE
Sbjct: 1081 QEQLKTVKTLAKEVWQEKAKVERLQRILEGEGNQEAGKELKAGELRLQLGVLRVTVADIE 1140
Query: 1141 KELAELRESQDRGKAAMENSVSEASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAH 1200
KELAELRESQDRGKAAMENSVSEASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAH
Sbjct: 1141 KELAELRESQDRGKAAMENSVSEASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAH 1200
Query: 1201 TLAPGQIDPEATCPACSLDVSHQVSTLVRRYEQLQDMVNSLAVSRPSKKAKLQRQDEELL 1260
TLAPGQIDPEATCPACSLDVSHQVSTLVRRYEQLQDMVNSLAVSRPSKKAKLQRQDEELL
Sbjct: 1201 TLAPGQIDPEATCPACSLDVSHQVSTLVRRYEQLQDMVNSLAVSRPSKKAKLQRQDEELL 1260
Query: 1261 GRVQSAILQVQGDCEKLNITTSNLIEDHRQKQKDIAMLYQGLEKLEKEKANREHLEMEID 1320
GRVQSAILQVQGDCEKLNITTSNLIEDHRQKQKDIAMLYQGLEKLEKEKANREHLEMEID
Sbjct: 1261 GRVQSAILQVQGDCEKLNITTSNLIEDHRQKQKDIAMLYQGLEKLEKEKANREHLEMEID 1320
Query: 1321 VKADKSALATKVSRVQFDATTEQLNHMMQELVAKMSGQEQDWQKMLDRLLTEMDNKLDRL 1380
VKADKSALATKVSRVQFDATTEQLNHMMQELVAKMSGQEQDWQKMLDRLLTEMDNKLDRL
Sbjct: 1321 VKADKSALATKVSRVQFDATTEQLNHMMQELVAKMSGQEQDWQKMLDRLLTEMDNKLDRL 1380
Query: 1381 ELDPVKQLLEDRWKSLRQQLRERPPLYQADEAAAMRRQLLAHFHCLSCDRPLETPVTGHA 1440
ELDPVKQLLEDRWKSLRQQLRERPPLYQADEAAAMRRQLLAHFHCLSCDRPLETPVTGHA
Sbjct: 1381 ELDPVKQLLEDRWKSLRQQLRERPPLYQADEAAAMRRQLLAHFHCLSCDRPLETPVTGHA 1440
Query: 1441 IPVTPAGPGLPGHHSIRPYTVFELEQVRQHSRNLKLGSAFPRGDLAQMEQSVGRLRSMHS 1500
IPVTPAGPGLPGHHSIRPYTVFELEQVRQHSRNLKLGSAFPRGDLAQMEQSVGRLRSMHS
Sbjct: 1441 IPVTPAGPGLPGHHSIRPYTVFELEQVRQHSRNLKLGSAFPRGDLAQMEQSVGRLRSMHS 1500
Query: 1501 KMLMNIEKVQIHFGGSTKASSQIIRELLHAQCLGSPCYKRVTDMADYTYSTVPRRCGGSH 1560
KMLMNIEKVQIHFGGSTKASSQIIRELLHAQCLGSPCYKRVTDMADYTYSTVPRRCGGSH
Sbjct: 1501 KMLMNIEKVQIHFGGSTKASSQIIRELLHAQCLGSPCYKRVTDMADYTYSTVPRRCGGSH 1560
Query: 1561 TLTYPYHRSRPQHLPRGLYPTEEIQIAMKHDEVDILGLDGHIYKGRMDTRLPGILRKDSS 1620
TLTYPYHRSRPQHLPRGLYPTEEIQIAMKHDEVDILGLDGHIYKGRMDTRLPGILRKDSS
Sbjct: 1561 TLTYPYHRSRPQHLPRGLYPTEEIQIAMKHDEVDILGLDGHIYKGRMDTRLPGILRKDSS 1620
Query: 1621 GTSKRKSQQPRPHVHRPPSLSSNGQLPSRPQSAQISAGNTSER 1663
GTSKRKSQQPRPHVHRPPSLSSNGQLPSRPQSAQISAGNTSER
Sbjct: 1621 GTSKRKSQQPRPHVHRPPSLSSNGQLPSRPQSAQISAGNTSER 1663
>gi|61175248 spermidine/spermine N1-acetyl transferase-like 1 [Homo
sapiens]
Length = 445
Score = 164 bits (415), Expect = 7e-40
Identities = 125/357 (35%), Positives = 159/357 (44%), Gaps = 13/357 (3%)
Query: 459 MDQSGLAQPGRDQHGLIQPGTGQHDLVQSGTGQGVLVQPGVDQPGMVQPGRFQRALVQPG 518
M G+ QPG Q G+ Q D+ Q G Q V QPG+ QP Q + Q + QP
Sbjct: 1 MSPPGMWQPGVQQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPD 60
Query: 519 AYQPGLVQPGADQIDVVQPGADQHGLVQSGADQSDLAQPGAVQHGLVQPGVDQRGLAQPR 578
A Q L ++Q ++QP G+ Q +Q + Q + QP + Q G+
Sbjct: 61 ANQSSLSD--SNQTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQAGM---- 114
Query: 579 ADHQRGLVPPGADQRGLVQPGADQHGLVQPGVDQHGLAQPGEVQRSLVQPGIVQRGLVQP 638
Q G P +Q G+ QPG Q G QPG+ L++ + S+ QPG QR Q
Sbjct: 115 --RQSGTNLPDINQPGMKQPGTWQLGRSQPGMWPQSLSELVLSEASISQPGPPQRAPSQS 172
Query: 639 GAVQRGLVQPGAVQRGLVQP-----GVDQRGLVQPGAVQRGLVQPGAVQHGLVQPGADQR 693
G Q Q G Q G+ QP + Q G QP Q G Q G Q G+ QPG Q
Sbjct: 173 GPRQSSTSQAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQIGMSQPGTWQT 232
Query: 694 GLVQPGVDQRGLVQPGVDQRGLVQPGMDQRGLIQPGADQPGLVQPGAGQLGMVQPGIGQQ 753
GL QP Q PG+ QRG+ QPGM Q+ Q G QPG Q Q GM PG GQ
Sbjct: 233 GLSQPVPRQPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQSSKNQTGMSHPGRGQP 292
Query: 754 GMVQPQADPHGLVQPGAYPLGLVQPGAYLHDLSQSGTYPRGLVQPGMDQYGLRQPGA 810
G+ +P GL Q L L QPG SQ G+ Q MD + +R A
Sbjct: 293 GIWEPGPSQPGLSQQDLNQLVLSQPGLSQPGRSQPSVSQMGMRQTSMDYFQIRHAEA 349
Score = 130 bits (327), Expect = 1e-29
Identities = 113/368 (30%), Positives = 154/368 (41%), Gaps = 39/368 (10%)
Query: 226 LEPTGMNQPGLVPASTYPHGVVPLSMGQLGVPPPEMDDRELIPFVVDEQRMLPP--SVPG 283
+ P GM QPG V + Q P+M + V + + P S
Sbjct: 1 MSPPGMWQPG----------VQQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSC 50
Query: 284 RDQQGLELPSTDQHGLVSVSAYQHGMTFPGTDQRSMEPLGMDQRGCVISGMGQQGLVPP- 342
++Q + P +Q L + Q G+ P M + M+Q + M Q + P
Sbjct: 51 KNQTDMSQPDANQSSLSDSN--QTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPS 108
Query: 343 ----GIDQQGLTLPVVDQHGLVLPFTDQHGLVSPGLMPISADQQGFVQPSLEATGFIQPG 398
G+ Q G LP ++Q G+ P T Q G PG+ P S + + S+ QPG
Sbjct: 109 MSQAGMRQSGTNLPDINQPGMKQPGTWQLGRSQPGMWPQSLSELVLSEASIS-----QPG 163
Query: 399 TEQHDLIQSGRFQRALVQRGAYQPGLVQP-----GADQRGLVRPGMDQSGLAQPGADQRG 453
Q QSG Q + Q G Q G+ QP Q G +P M Q G +Q G Q G
Sbjct: 164 PPQRAPSQSGPRQSSTSQAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQIG 223
Query: 454 LVWPGMDQSGLAQPGRDQHGLIQPGTGQHDLVQSGTGQGVLVQPGVDQPGMVQPGRFQRA 513
+ PG Q+GL+QP Q PG Q + Q G Q V Q G+ QPG Q + Q
Sbjct: 224 MSQPGTWQTGLSQPVPRQPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQSSKNQTG 283
Query: 514 LVQPGAYQPGLVQPGADQIDVVQPGADQHGLVQSGADQSDLAQPGAVQHGLVQPGVDQRG 573
+ PG QPG + +PG Q GL Q +Q L+QPG Q G QP V Q G
Sbjct: 284 MSHPGRGQPG----------IWEPGPSQPGLSQQDLNQLVLSQPGLSQPGRSQPSVSQMG 333
Query: 574 LAQPRADH 581
+ Q D+
Sbjct: 334 MRQTSMDY 341
Score = 127 bits (318), Expect = 1e-28
Identities = 105/338 (31%), Positives = 142/338 (42%), Gaps = 19/338 (5%)
Query: 282 PGRDQQGLELPSTDQHGLVSVSAYQHGMTFPGTDQRSMEPLGMDQRGC---VISGMGQQG 338
PG QQ P Q G+ Q G+ P T Q M Q +S Q G
Sbjct: 14 PGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPDANQSSLSDSNQTG 73
Query: 339 LVPPGIDQQGLTLPVVDQHGLVLPFTDQHGLVSPGLMPISADQQGFVQPSLEATGFIQPG 398
++ P G+ ++Q L +Q + P + Q G P + G QPG
Sbjct: 74 IIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQAGMRQSGTNLPDINQPGMKQPG 133
Query: 399 TEQHDLIQSGRFQRALVQRGAYQPGLVQPGADQRGLVRPGMDQSGLAQPGADQRGLVWPG 458
T Q Q G + ++L + + + QPG QR + G QS +Q G +Q
Sbjct: 134 TWQLGRSQPGMWPQSLSELVLSEASISQPGPPQRAPSQSGPRQSSTSQAGTNQ------- 186
Query: 459 MDQSGLAQP-----GRDQHGLIQPGTGQHDLVQSGTGQGVLVQPGVDQPGMVQPGRFQRA 513
SG++QP Q G QP Q QSGT Q + QPG Q G+ QP Q
Sbjct: 187 ---SGISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQIGMSQPGTWQTGLSQPVPRQPN 243
Query: 514 LVQPGAYQPGLVQPGADQIDVVQPGADQHGLVQSGADQSDLAQPGAVQHGLVQPGVDQRG 573
PG +Q G+ QPG Q Q G Q G QS +Q+ ++ PG Q G+ +PG Q G
Sbjct: 244 KSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQSSKNQTGMSHPGRGQPGIWEPGPSQPG 303
Query: 574 LAQPRADHQRGLVPPGADQRGLVQPGADQHGLVQPGVD 611
L+Q +Q L PG Q G QP Q G+ Q +D
Sbjct: 304 LSQQDL-NQLVLSQPGLSQPGRSQPSVSQMGMRQTSMD 340
Score = 125 bits (315), Expect = 3e-28
Identities = 102/335 (30%), Positives = 142/335 (42%), Gaps = 20/335 (5%)
Query: 615 LAQPGEVQRSLVQPGIVQR-----GLVQPGAVQRGLVQPGAVQRGLVQPGVDQRGLVQPG 669
++ PG Q + QPGI Q+ + QPG Q+ QPG Q Q +Q + QP
Sbjct: 1 MSPPGMWQPGVQQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPD 60
Query: 670 AVQRGLVQPGAVQHGLVQPGADQRGLVQPGVDQRGLVQPGVDQRGLVQPGMDQRGLIQ-- 727
A Q L Q G++QP G+ Q ++Q ++Q + QP M Q G+ Q
Sbjct: 61 ANQSSLSDSN--QTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQAGMRQSG 118
Query: 728 ---PGADQPGLVQPGAGQLGMVQPGIGQQGMVQPQADPHGLVQPGAYPLGLVQPGAYLHD 784
P +QPG+ QPG QLG QPG+ Q + + + QPG Q G
Sbjct: 119 TNLPDINQPGMKQPGTWQLGRSQPGMWPQSLSELVLSEASISQPGPPQRAPSQSGPRQSS 178
Query: 785 LSQSGTYPRGLVQPGMDQYGLRQPGAYQPGLIAPGTKLRGSSTFQAD-----STGFISVR 839
SQ+GT G+ QP M Q +RQ G QP + GT G+S TG
Sbjct: 179 TSQAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQIGMSQPGTWQTGLSQPV 238
Query: 840 PYQHGMVPPGREQYGQVSPLLASQGLASPGIDRRSLVPPETYQQGLMHPGTDQ---HSPI 896
P Q PPG Q G P ++ Q + G+ + Q G+ HPG Q P
Sbjct: 239 PRQPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQSSKNQTGMSHPGRGQPGIWEPG 298
Query: 897 PLSTGLGSTHPDQQHVASPGPGEHDQVYPDAAQHG 931
P GL +Q ++ PG + + P +Q G
Sbjct: 299 PSQPGLSQQDLNQLVLSQPGLSQPGRSQPSVSQMG 333
Score = 125 bits (313), Expect = 4e-28
Identities = 113/366 (30%), Positives = 151/366 (41%), Gaps = 20/366 (5%)
Query: 563 GLVQPGVDQRGLAQPRADHQRGLVPPGADQRGLVQPGADQHGLVQPGVDQHGLAQPGEVQ 622
G+ QPGV Q G++Q H + PG Q+ QPG Q Q +Q ++QP Q
Sbjct: 5 GMWQPGVQQPGISQQVPSHP-DMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPDANQ 63
Query: 623 RSLVQPGIVQRGLVQP-----GAVQRGLVQPGAVQRGLVQPGVDQRGLVQPGAVQRGLVQ 677
SL Q G++QP G Q + Q A + Q + Q + Q G Q G
Sbjct: 64 SSLSDSN--QTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQAGMRQSGTNL 121
Query: 678 PGAVQHGLVQPGADQRGLVQPGVDQRGLVQPGVDQRGLVQPGMDQRGLIQPGADQPGLVQ 737
P Q G+ QPG Q G QPG+ + L + + + + QPG QR Q G Q Q
Sbjct: 122 PDINQPGMKQPGTWQLGRSQPGMWPQSLSELVLSEASISQPGPPQRAPSQSGPRQSSTSQ 181
Query: 738 PGAGQLGMVQPGIGQQGMVQPQADPHGLVQPGAYPLGLVQPGAYLHDLSQSGTYPRGLVQ 797
G Q G+ QP + Q M Q G QP +G Q G +SQ GT+ GL Q
Sbjct: 182 AGTNQSGISQPVMWQLDMRQS-----GGSQPSMRQVGTSQSGTSQIGMSQPGTWQTGLSQ 236
Query: 798 PGMDQYGLRQPGAYQPGLIAPGTKLRGSSTFQADSTGFISVRPYQHGMVPPGREQYGQVS 857
P Q PG +Q G+ PG + S G Q GM PGR Q G
Sbjct: 237 PVPRQPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQSSKNQTGMSHPGRGQPGIWE 296
Query: 858 PLLASQGLASPGIDRRSLVPPETYQQGLMHPGTDQHSPIPLSTGLGSTHPDQQHVASPGP 917
P G + PG+ ++ L Q GL PG Q P G+ T D +
Sbjct: 297 P-----GPSQPGLSQQDLNQLVLSQPGLSQPGRSQ--PSVSQMGMRQTSMDYFQIRHAEA 349
Query: 918 GEHDQV 923
G+ ++
Sbjct: 350 GDCPEI 355
Score = 112 bits (279), Expect = 4e-24
Identities = 107/362 (29%), Positives = 151/362 (41%), Gaps = 50/362 (13%)
Query: 192 RPGPVQQDLPLARDQPSSVPASQSQVHLRPDRRGLEP-------TGMNQPGLVPAS---T 241
+PG + Q +P D S P QV +P R + T M+QP +S +
Sbjct: 13 QPG-ISQQVPSHPDM--SQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPDANQSSLSDS 69
Query: 242 YPHGVVPLSMGQLGVPPPEMDDRELIPFVVDEQRMLPPSVP--GRDQQGLELPSTDQHGL 299
G++ S LG+ +M+ + +++ M PS+ G Q G LP +Q G+
Sbjct: 70 NQTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQAGMRQSGTNLPDINQPGM 129
Query: 300 VSVSAYQHGMTFPGTDQRSMEPLGMDQRGCVISGMGQQGLVPPGIDQQGLTLPVVDQHGL 359
+Q G + PG +S+ L + + + + Q G Q G Q G
Sbjct: 130 KQPGTWQLGRSQPGMWPQSLSELVLSE-----ASISQPGPPQRAPSQSGPRQSSTSQAG- 183
Query: 360 VLPFTDQHGLVSPGLMPISADQQGFVQPSLEATGFIQPGTEQHDLIQSGRFQRALVQRGA 419
T+Q G+ P + + Q G QPS+ G Q GT Q + Q G
Sbjct: 184 ----TNQSGISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQIGMSQPG----------T 229
Query: 420 YQPGLVQPGADQRGLVRPGMDQSGLAQPGADQRGLVWPGMDQSGLAQPGRDQHGLIQPGT 479
+Q GL QP Q PGM Q G+ QPG Q+ GM Q G +Q ++Q G+ PG
Sbjct: 230 WQTGLSQPVPRQPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQSSKNQTGMSHPGR 289
Query: 480 GQHDLVQSGTGQGVLVQPGVDQPGMVQPGRFQRALVQPGAYQPGLVQPGADQIDVVQPGA 539
G QPG+ +PG QPG Q+ L Q QPGL QPG Q V Q G
Sbjct: 290 G---------------QPGIWEPGPSQPGLSQQDLNQLVLSQPGLSQPGRSQPSVSQMGM 334
Query: 540 DQ 541
Q
Sbjct: 335 RQ 336
>gi|222446620 hypothetical protein LOC342346 [Homo sapiens]
Length = 1141
Score = 107 bits (267), Expect = 1e-22
Identities = 69/209 (33%), Positives = 111/209 (53%), Gaps = 13/209 (6%)
Query: 1225 STLVRRYEQLQDMVNSLAVSRPSKKAKLQRQDEELLGRVQSAILQVQGDCEKLNITTSNL 1284
S+L + LQ + SL SR EE L R+ +++ D IT
Sbjct: 725 SSLGTTVDILQKKIGSLQKSRLK---------EEELERIWGNQIEMMKD---RYITLDKA 772
Query: 1285 IEDHRQKQKDIAMLYQGLEKLEKEKANREHLEMEIDVKADKSALATKVSRVQFDATTEQL 1344
+E+ + + + L +++LE K N+ +E E+ KAD+SALA K SRV + +L
Sbjct: 773 VENLQIRMDEFKTLQAQIKRLEMNKVNKSTMEEELREKADRSALAGKASRVDLETVALEL 832
Query: 1345 NHMMQELVAKMSGQEQDWQKMLDRLLTEMDNKLDRLELDPVKQLLEDRWKSLRQQLRERP 1404
N M+Q ++ K++ E W+K ++ L +++ KL +LDP+K+ +E+ WK +R+ L E
Sbjct: 833 NEMIQGILFKVTIHEDSWKKAMEELSKDVNTKLVHSDLDPLKKEMEEVWKIVRKLLIEGL 892
Query: 1405 PLYQADEAAAMRRQLLAHFHCLSCDRPLE 1433
L D AA RR+L C+SCDRP+E
Sbjct: 893 RL-DPDSAAGFRRKLFKRVKCISCDRPVE 920
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 94.7 bits (234), Expect = 6e-19
Identities = 94/318 (29%), Positives = 129/318 (40%), Gaps = 34/318 (10%)
Query: 471 QHGLIQPGTGQHDLVQSGT--------GQGVLVQPGVDQPGMVQPG--RFQRALVQPGAY 520
Q +P T Q D+V+ + + + QP +P QPG + Q +P A
Sbjct: 275 QRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQ 334
Query: 521 QPGLVQPGADQIDVVQPGADQHGLVQSGADQSDLAQPGAVQHGLVQPGVDQRG---LAQP 577
GL +P A Q V+P G + A A+P A Q G +P +Q G LAQP
Sbjct: 335 PSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQP 394
Query: 578 RADHQRGLVPPGADQRGLVQPGADQHGLVQPGVDQHGLAQPGEVQRSLVQPGIVQRGLVQ 637
G+ A Q G +P Q G +P Q GL P + PG + + Q
Sbjct: 395 P-----GVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKA------PGPTKTPVQQ 443
Query: 638 PG-----AVQRGLVQPGAVQRGLVQPGVDQRGLVQPGAVQRGLVQPGAVQHGLVQPGADQ 692
PG A Q G + A Q G +P G +P Q G +P Q G +P + Q
Sbjct: 444 PGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQ 503
Query: 693 RGLVQPGVDQRGLVQPGVDQRGLVQPGMDQRGLIQPGADQPGLVQPGAGQLGMVQPGIGQ 752
G +P Q G +P Q G +P Q G +P A QP +P A Q +P + Q
Sbjct: 504 PGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQ--STKP-VSQ 560
Query: 753 QGMVQPQADPHGLVQPGA 770
G +P P V P A
Sbjct: 561 TGSGKPLQPP--TVSPSA 576
Score = 92.4 bits (228), Expect = 3e-18
Identities = 113/383 (29%), Positives = 152/383 (39%), Gaps = 48/383 (12%)
Query: 467 PGRDQHGLIQPGTG------QHDLVQS---GTG---QGVLVQPGVD------QPGMVQPG 508
PGRD L Q GT Q + ++S GTG QG P D Q +P
Sbjct: 225 PGRDP--LQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQ 282
Query: 509 RFQRALVQPGAYQPGLVQPGADQIDVVQPG---ADQHGLVQSGADQSDLAQPGAVQHGLV 565
Q +V+ + +P L P I PG A Q G +S Q A+P A GL
Sbjct: 283 TKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKS---QPGPAKPPAQPSGLT 339
Query: 566 QPGVDQRGLAQPRADHQRGLVPPGADQRGLVQPGADQHGLVQPGVDQHG---LAQPGEVQ 622
+P Q G +P G P A G +P A Q G +P +Q G LAQP V
Sbjct: 340 KPLAQQPGTVKPPVQPP-GTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVG 398
Query: 623 RSLVQPGIVQRGLVQPGAVQRGLVQPGAVQRGLVQPGVDQRGLVQPGAVQRGLVQPG--- 679
++ Q Q G +P Q G +P A Q GL P PG + + QPG
Sbjct: 399 KTPAQ----QPGPAKPPTQQVGTPKPLAQQPGLQSPAK------APGPTKTPVQQPGPGK 448
Query: 680 --AVQHGLVQPGADQRGLVQPGVDQRGLVQPGVDQRGLVQPGMDQRGLIQPGADQPGLVQ 737
A Q G + A Q G +P G +P Q G +P Q G +P + QPG +
Sbjct: 449 IPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTK 508
Query: 738 PGAGQLGMVQPGIGQQGMVQPQADPHGLVQPGAYPLGLVQPGAY--LHDLSQSGTYPRGL 795
P Q G +P Q G +P + G +P A +P A +SQ+G+ + L
Sbjct: 509 PPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGS-GKPL 567
Query: 796 VQPGMDQYGLRQPGAYQPGLIAP 818
P + + P P I P
Sbjct: 568 QPPTVSPSAKQPPSQGLPKTICP 590
Score = 89.0 bits (219), Expect = 4e-17
Identities = 128/551 (23%), Positives = 194/551 (35%), Gaps = 111/551 (20%)
Query: 89 PEGTLSGDSTKQPSI--EQALDSA-----SGLGPDRTASGSGGTAHPSDGVSSREQSKVP 141
P+G++ + + PS+ +Q LDS+ SG PD G + + R + K+P
Sbjct: 67 PKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLP 126
Query: 142 SGTGRQ-QQPRARDEAGVPRLHQSSTFQ---------------------FKSDSDRHRSR 179
+ ++ + H+SS F SD S+
Sbjct: 127 GRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQ 186
Query: 180 EKLTSTQ----------------PRRNARPGPVQQDLPLARDQPSSVPASQSQVHLRPDR 223
E+ T Q P + P P+ + RD +S +P++
Sbjct: 187 EETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEK 246
Query: 224 RGLEPTGMNQPGLVPAST--YPHGVVPLSMGQLGVPPPEMDDRELIPFVVDEQRMLPPSV 281
+P G +P P T H +PL Q P+ +++ + PS+
Sbjct: 247 IKSQPPGTGKPIQGPTQTPQTDHAKLPL---QRDASRPQTKQADIV-----RGESVKPSL 298
Query: 282 PGRDQQGLELPSTDQHGLVSVSAYQHGMTFPGTDQRSMEPLGMDQRGCVISGMGQQGLVP 341
P + ++ P+ + P Q E Q G
Sbjct: 299 PSPSKPPIQQPTPGK---------------PPAQQPGHEK-------------SQPGPAK 330
Query: 342 PGIDQQGLTLPVVDQHGLVLPFTDQHGLVSPGLMPISADQQGFVQPSLEATGFIQPGTEQ 401
P GLT P+ Q G V P G P P+ G +P + TG +P +EQ
Sbjct: 331 PPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPL-----GPAKPPAQQTGSEKPSSEQ 385
Query: 402 HDLIQSGRFQRALVQRGAYQPGLVQPGADQRGLVRPGMDQSGLAQPGADQRGLVWPGMDQ 461
+AL Q PG+ + A Q G +P Q G +P A Q GL Q
Sbjct: 386 PG-------PKALAQ----PPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGL------Q 428
Query: 462 SGLAQPGRDQHGLIQPGTGQHDLVQSGTGQGVLVQPGVDQPGMVQPGRFQRALVQPGAYQ 521
S PG + + QPG G+ Q+G G+ Q G +P PG + QPG +
Sbjct: 429 SPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAK 488
Query: 522 PGLVQPGADQIDVVQPGADQHGLVQSGADQSDLAQPGAVQHGLVQPGVDQRGLAQPRADH 581
P QPG+ +P + Q G + Q A+P Q G +P Q G A+P A
Sbjct: 489 PPPQQPGS-----AKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSA-Q 542
Query: 582 QRGLVPPGADQ 592
Q P A Q
Sbjct: 543 QPSPAKPSAQQ 553
Score = 84.3 bits (207), Expect = 9e-16
Identities = 92/320 (28%), Positives = 122/320 (38%), Gaps = 26/320 (8%)
Query: 621 VQRSLVQPGIVQRGLVQPGAVQRGLVQPGAVQRGLVQPGVDQRGLVQPG--AVQRGLVQP 678
+QR +P Q +V+ +V+ L P + + QP + QPG Q G +P
Sbjct: 274 LQRDASRPQTKQADIVRGESVKPSLPSPS--KPPIQQPTPGKPPAQQPGHEKSQPGPAKP 331
Query: 679 GAVQHGLVQPGADQRGLVQPGVDQRGLVQPGVDQRGLVQPGMDQRGLIQPGADQPG---L 735
A GL +P A Q G V+P V G +P G +P Q G +P ++QPG L
Sbjct: 332 PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKAL 391
Query: 736 VQP-GAGQLGMVQPGIGQQGMVQPQADPHGLVQPGAYPLGLVQPGAYLHDLSQSGTYPRG 794
QP G G+ QPG +P G +P A GL P G
Sbjct: 392 AQPPGVGKTPAQQPG-----PAKPPTQQVGTPKPLAQQPGLQSPA------KAPGPTKTP 440
Query: 795 LVQPGMDQYGLRQPG-----AYQPGLIAPGTKLRGSSTFQADSTGFISVRPYQHGMVPPG 849
+ QPG + +Q G A Q G P ++L G + G P Q G P
Sbjct: 441 VQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPP 500
Query: 850 REQYGQVSPLLASQGLASPGIDRRSLVPPETYQQGLMHPGTDQHSPIPLSTGLGSTHPDQ 909
+Q G P G A P + P + Q G P Q SP S ST P
Sbjct: 501 SQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPS-AQQSTKPVS 559
Query: 910 QHVASPGPGEHDQVYPDAAQ 929
Q S P + V P A Q
Sbjct: 560 Q-TGSGKPLQPPTVSPSAKQ 578
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 94.7 bits (234), Expect = 6e-19
Identities = 94/318 (29%), Positives = 129/318 (40%), Gaps = 34/318 (10%)
Query: 471 QHGLIQPGTGQHDLVQSGT--------GQGVLVQPGVDQPGMVQPG--RFQRALVQPGAY 520
Q +P T Q D+V+ + + + QP +P QPG + Q +P A
Sbjct: 275 QRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQ 334
Query: 521 QPGLVQPGADQIDVVQPGADQHGLVQSGADQSDLAQPGAVQHGLVQPGVDQRG---LAQP 577
GL +P A Q V+P G + A A+P A Q G +P +Q G LAQP
Sbjct: 335 PSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQP 394
Query: 578 RADHQRGLVPPGADQRGLVQPGADQHGLVQPGVDQHGLAQPGEVQRSLVQPGIVQRGLVQ 637
G+ A Q G +P Q G +P Q GL P + PG + + Q
Sbjct: 395 P-----GVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKA------PGPTKTPVQQ 443
Query: 638 PG-----AVQRGLVQPGAVQRGLVQPGVDQRGLVQPGAVQRGLVQPGAVQHGLVQPGADQ 692
PG A Q G + A Q G +P G +P Q G +P Q G +P + Q
Sbjct: 444 PGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQ 503
Query: 693 RGLVQPGVDQRGLVQPGVDQRGLVQPGMDQRGLIQPGADQPGLVQPGAGQLGMVQPGIGQ 752
G +P Q G +P Q G +P Q G +P A QP +P A Q +P + Q
Sbjct: 504 PGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQ--STKP-VSQ 560
Query: 753 QGMVQPQADPHGLVQPGA 770
G +P P V P A
Sbjct: 561 TGSGKPLQPP--TVSPSA 576
Score = 92.4 bits (228), Expect = 3e-18
Identities = 113/383 (29%), Positives = 152/383 (39%), Gaps = 48/383 (12%)
Query: 467 PGRDQHGLIQPGTG------QHDLVQS---GTG---QGVLVQPGVD------QPGMVQPG 508
PGRD L Q GT Q + ++S GTG QG P D Q +P
Sbjct: 225 PGRDP--LQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQ 282
Query: 509 RFQRALVQPGAYQPGLVQPGADQIDVVQPG---ADQHGLVQSGADQSDLAQPGAVQHGLV 565
Q +V+ + +P L P I PG A Q G +S Q A+P A GL
Sbjct: 283 TKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKS---QPGPAKPPAQPSGLT 339
Query: 566 QPGVDQRGLAQPRADHQRGLVPPGADQRGLVQPGADQHGLVQPGVDQHG---LAQPGEVQ 622
+P Q G +P G P A G +P A Q G +P +Q G LAQP V
Sbjct: 340 KPLAQQPGTVKPPVQPP-GTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVG 398
Query: 623 RSLVQPGIVQRGLVQPGAVQRGLVQPGAVQRGLVQPGVDQRGLVQPGAVQRGLVQPG--- 679
++ Q Q G +P Q G +P A Q GL P PG + + QPG
Sbjct: 399 KTPAQ----QPGPAKPPTQQVGTPKPLAQQPGLQSPAK------APGPTKTPVQQPGPGK 448
Query: 680 --AVQHGLVQPGADQRGLVQPGVDQRGLVQPGVDQRGLVQPGMDQRGLIQPGADQPGLVQ 737
A Q G + A Q G +P G +P Q G +P Q G +P + QPG +
Sbjct: 449 IPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTK 508
Query: 738 PGAGQLGMVQPGIGQQGMVQPQADPHGLVQPGAYPLGLVQPGAY--LHDLSQSGTYPRGL 795
P Q G +P Q G +P + G +P A +P A +SQ+G+ + L
Sbjct: 509 PPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGS-GKPL 567
Query: 796 VQPGMDQYGLRQPGAYQPGLIAP 818
P + + P P I P
Sbjct: 568 QPPTVSPSAKQPPSQGLPKTICP 590
Score = 89.0 bits (219), Expect = 4e-17
Identities = 128/551 (23%), Positives = 194/551 (35%), Gaps = 111/551 (20%)
Query: 89 PEGTLSGDSTKQPSI--EQALDSA-----SGLGPDRTASGSGGTAHPSDGVSSREQSKVP 141
P+G++ + + PS+ +Q LDS+ SG PD G + + R + K+P
Sbjct: 67 PKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLP 126
Query: 142 SGTGRQ-QQPRARDEAGVPRLHQSSTFQ---------------------FKSDSDRHRSR 179
+ ++ + H+SS F SD S+
Sbjct: 127 GRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQ 186
Query: 180 EKLTSTQ----------------PRRNARPGPVQQDLPLARDQPSSVPASQSQVHLRPDR 223
E+ T Q P + P P+ + RD +S +P++
Sbjct: 187 EETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEK 246
Query: 224 RGLEPTGMNQPGLVPAST--YPHGVVPLSMGQLGVPPPEMDDRELIPFVVDEQRMLPPSV 281
+P G +P P T H +PL Q P+ +++ + PS+
Sbjct: 247 IKSQPPGTGKPIQGPTQTPQTDHAKLPL---QRDASRPQTKQADIV-----RGESVKPSL 298
Query: 282 PGRDQQGLELPSTDQHGLVSVSAYQHGMTFPGTDQRSMEPLGMDQRGCVISGMGQQGLVP 341
P + ++ P+ + P Q E Q G
Sbjct: 299 PSPSKPPIQQPTPGK---------------PPAQQPGHEK-------------SQPGPAK 330
Query: 342 PGIDQQGLTLPVVDQHGLVLPFTDQHGLVSPGLMPISADQQGFVQPSLEATGFIQPGTEQ 401
P GLT P+ Q G V P G P P+ G +P + TG +P +EQ
Sbjct: 331 PPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPL-----GPAKPPAQQTGSEKPSSEQ 385
Query: 402 HDLIQSGRFQRALVQRGAYQPGLVQPGADQRGLVRPGMDQSGLAQPGADQRGLVWPGMDQ 461
+AL Q PG+ + A Q G +P Q G +P A Q GL Q
Sbjct: 386 PG-------PKALAQ----PPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGL------Q 428
Query: 462 SGLAQPGRDQHGLIQPGTGQHDLVQSGTGQGVLVQPGVDQPGMVQPGRFQRALVQPGAYQ 521
S PG + + QPG G+ Q+G G+ Q G +P PG + QPG +
Sbjct: 429 SPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAK 488
Query: 522 PGLVQPGADQIDVVQPGADQHGLVQSGADQSDLAQPGAVQHGLVQPGVDQRGLAQPRADH 581
P QPG+ +P + Q G + Q A+P Q G +P Q G A+P A
Sbjct: 489 PPPQQPGS-----AKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSA-Q 542
Query: 582 QRGLVPPGADQ 592
Q P A Q
Sbjct: 543 QPSPAKPSAQQ 553
Score = 84.3 bits (207), Expect = 9e-16
Identities = 92/320 (28%), Positives = 122/320 (38%), Gaps = 26/320 (8%)
Query: 621 VQRSLVQPGIVQRGLVQPGAVQRGLVQPGAVQRGLVQPGVDQRGLVQPG--AVQRGLVQP 678
+QR +P Q +V+ +V+ L P + + QP + QPG Q G +P
Sbjct: 274 LQRDASRPQTKQADIVRGESVKPSLPSPS--KPPIQQPTPGKPPAQQPGHEKSQPGPAKP 331
Query: 679 GAVQHGLVQPGADQRGLVQPGVDQRGLVQPGVDQRGLVQPGMDQRGLIQPGADQPG---L 735
A GL +P A Q G V+P V G +P G +P Q G +P ++QPG L
Sbjct: 332 PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKAL 391
Query: 736 VQP-GAGQLGMVQPGIGQQGMVQPQADPHGLVQPGAYPLGLVQPGAYLHDLSQSGTYPRG 794
QP G G+ QPG +P G +P A GL P G
Sbjct: 392 AQPPGVGKTPAQQPG-----PAKPPTQQVGTPKPLAQQPGLQSPA------KAPGPTKTP 440
Query: 795 LVQPGMDQYGLRQPG-----AYQPGLIAPGTKLRGSSTFQADSTGFISVRPYQHGMVPPG 849
+ QPG + +Q G A Q G P ++L G + G P Q G P
Sbjct: 441 VQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPP 500
Query: 850 REQYGQVSPLLASQGLASPGIDRRSLVPPETYQQGLMHPGTDQHSPIPLSTGLGSTHPDQ 909
+Q G P G A P + P + Q G P Q SP S ST P
Sbjct: 501 SQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPS-AQQSTKPVS 559
Query: 910 QHVASPGPGEHDQVYPDAAQ 929
Q S P + V P A Q
Sbjct: 560 Q-TGSGKPLQPPTVSPSAKQ 578
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 62.4 bits (150), Expect = 4e-09
Identities = 134/566 (23%), Positives = 232/566 (40%), Gaps = 71/566 (12%)
Query: 868 PGIDRRSLVPPETYQQGLMHPGTDQHSPIPLSTGLGSTHPDQQHVASPGPGEHDQVYPDA 927
PG R P E +GL P T + SP GS P SP + D P+A
Sbjct: 1458 PGSPARD-APAEGSGEGLNSPSTLECSP-------GSQPPSPGPATSPASPDLD---PEA 1506
Query: 928 AQHGHAFSLFDSHDSMYPGYRGPGYLSADQHGQEGLDPNRTRASDRHGIPAQKAPGQDVT 987
+ L + + SA ++ R A+ R QKA +
Sbjct: 1507 VRGALREFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSR-ARQLQKAVAESEE 1565
Query: 988 LFRSPDSVDRVLSEGSEVSSEVLSERRNSLRRMSSSFPTAVETFHLMGELSSLYVGLKES 1047
RS D R+ +E++ + S RR+ R ++ A L L + L+ S
Sbjct: 1566 ARRSVDG--RLSGVQAELALQEESVRRSERERRATLDQVAT----LERSLQATESELRAS 1619
Query: 1048 MKDLDEEQAGQTDLE----KIQFLLAQMVKRTIPPELQEQLKTVKTLAKEVW--QEKAKV 1101
+ + + +A +T LE +++ +L RT+ ELQ + + + +A+
Sbjct: 1620 QEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQA 1679
Query: 1102 ERLQRILEGEGNQEAGKELKAGELRLQLGVLRVTVADIEKELAELRESQDRG-------K 1154
+ LQ ++ Q A E+KAG L+L + L +A +E+ LR+ + RG
Sbjct: 1680 QALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRD-KVRGLTEALAQS 1738
Query: 1155 AAMENSVSEASLYLQDQL---DKLRMIIESMLTSSSTLLS-----MSMAPHKAHTLAPGQ 1206
+A NS + +L+LQ L + R +++ L ++ LS S + TL
Sbjct: 1739 SASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEV 1798
Query: 1207 IDPEATCPACSLDVSHQVSTLVRRYEQLQDMVNSLAVSRPSKKAKLQRQDEELLGRVQSA 1266
D E ++ Q+ L Q Q+ + A++ K +R +E LG +Q A
Sbjct: 1799 ADLELQ----RVEAEGQLQQLREVLRQRQE-GEAAALNTVQKLQDERRLLQERLGSLQRA 1853
Query: 1267 ILQVQGDCEKLNITTSNLIEDHRQKQKDIAMLYQGLEKLEKEKANREHLEMEIDVKADKS 1326
+ Q+ + EK + S L + +KD L + L+K+E+EK R H E + + A+K
Sbjct: 1854 LAQL--EAEKREVERSAL-----RLEKDRVALRRTLDKVEREKL-RSH-EDTVRLSAEKG 1904
Query: 1327 ALATKVSRVQFDATTEQLNHMMQELVAKMSGQEQDWQKMLDRLLTEMDNKLDRLELD--- 1383
L ++ + + Q +Q+L A++ EQ E+D + +LEL
Sbjct: 1905 RLDRTLTGAELELAEAQ--RQIQQLEAQVVVLEQSHSP----AQLEVDAQQQQLELQQEV 1958
Query: 1384 --------PVKQLLEDRWKSLRQQLR 1401
++ LE R ++ RQ++R
Sbjct: 1959 ERLRSAQAQTERTLEARERAHRQRVR 1984
Score = 53.9 bits (128), Expect = 1e-06
Identities = 106/475 (22%), Positives = 193/475 (40%), Gaps = 56/475 (11%)
Query: 957 QHGQEGLDPNRTRASDRHGIPAQKAPGQDVTLFRSPDSVDRVLSEGSEVSSEVLSERRNS 1016
Q QE L R R + Q L RS ++++ + S ++ E++ E R +
Sbjct: 630 QAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELV-EVREA 688
Query: 1017 LRRMSSSFPTAVETFHLMGELSSLYVGLKESMKDLDEEQAGQTDLEKIQFLLAQMVKRTI 1076
L R + + L E + L + +AG+ +LE L+ R
Sbjct: 689 LSRATL-------------QRDMLQAEKAEVAEALTKAEAGRVELE-----LSMTKLRAE 730
Query: 1077 PPELQEQLKTVKTLAKEVWQEKAKVERLQRILEGEGNQEAGKELKAGELRLQLGVLRVTV 1136
LQ+ L + L + + Q+K + RL LE E + G++ +A + TV
Sbjct: 731 EASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQ--------EATV 782
Query: 1137 ADIEKE-LAELRESQDRGKAAMENSV---SEASLYLQDQLDKLR----MIIESMLTSSST 1188
A E+E L ELR Q+ + +E S+ +A L+ QL LR + E + S
Sbjct: 783 AREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQ 842
Query: 1189 LLSMSMAPHKAHTLAPGQIDPEATCPACSLDVSHQVSTLVRRYEQLQDMVNSLAVSRPSK 1248
L +A A Q++ + + L + + L V +A R +
Sbjct: 843 LSGREQELEQARREAQRQVEALER-------AAREKEALAKEHAGL--AVQLVAAEREGR 893
Query: 1249 -----KAKLQRQDEELLG---RVQSAILQVQGDCEKLNITTSNLIEDHRQKQKDIAMLYQ 1300
+L+ + E L G VQ + Q++ E+L L+ ++A L Q
Sbjct: 894 TLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQ 953
Query: 1301 GLEKLEKEKANREHLEMEIDVKADKSALATKVSRVQFDATTEQLNHMMQELVAKMSGQEQ 1360
+ +++ + + L + V+A++ A A+ R Q A E L + +E A E
Sbjct: 954 QIIATQEKASLDKELMAQKLVQAEREAQAS--LREQRAAHEEDLQRLQREKEAAWRELEA 1011
Query: 1361 DWQKMLDRLLTEMDNKLDRLELDPVKQLLEDRWKSLRQQLRERPPLYQADEAAAM 1415
+ ++ +L E + L RLE + K+ L + +L+Q+ E L ++++ A+
Sbjct: 1012 ERAQLQSQLQREQEELLARLEAE--KEELSEEIAALQQERDEGLLLAESEKQQAL 1064
Score = 42.7 bits (99), Expect = 0.003
Identities = 93/428 (21%), Positives = 169/428 (39%), Gaps = 81/428 (18%)
Query: 1026 TAVETFHLMGELSSLYVGLKESMKDLDE-----EQAGQTDLEKIQFLLAQMVKRTIPPEL 1080
T + L GEL+ ++E+ L E + LEK L AQ+ + +L
Sbjct: 317 TERDLLQLGGELARTSRAVQEAGLGLSTGLRLAESRAEAALEKQALLQAQLEE-----QL 371
Query: 1081 QEQLKTVKTLAKEVWQE-------KAKVERL---------QRILEGEGNQEAGKELKAGE 1124
++++ K LA++ Q A+V L Q + + + N++ ++L+A E
Sbjct: 372 RDKVLREKDLAQQQMQSDLDKADLSARVTELGLAVKRLEKQNLEKDQVNKDLTEKLEALE 431
Query: 1125 -LRLQLGVLRVTVADIEKELAELRESQDRGKAAMENSVSEASLYLQDQLDKLRMIIESML 1183
LRLQ E A L G +++A L + +L +
Sbjct: 432 SLRLQ-------------EQAALETEDGEGLQQTLRDLAQAVLSDSESGVQLSGSERTAD 478
Query: 1184 TSSSTLLSMS----MAPHKAHTLAPGQIDPEATCPACS----LDVSH--------QVSTL 1227
S+ +L +S +P + + G+ PACS L + H QV +
Sbjct: 479 ASNGSLRGLSGQRTPSPPRRSSPGRGRSPRRGPSPACSDSSTLALIHSALHKRQLQVQDM 538
Query: 1228 VRRYEQLQDMVNSLAVSRPSKKAKLQRQDEELLGRVQSAILQVQGDCEKLNITTSNLIED 1287
RYE QD++ +L +++ + +E+L ++L T ++
Sbjct: 539 RGRYEASQDLLGTLRKQLSDSESERRALEEQL---------------QRLRDKTDGAMQA 583
Query: 1288 HRQKQKDIAMLYQGLEKLEKEKANREHLEMEIDVKADKSALATKVSRVQFDATTEQLNHM 1347
H Q+++ L E L +EK+N H +++ A + A + R + A E+L
Sbjct: 584 HEDAQREVQRLRSANELLSREKSNLAH-SLQV---AQQQAEELRQEREKLQAAQEELRRQ 639
Query: 1348 MQELVAKMSGQEQDWQKMLDRLLTEMDNKLDRLELDP---VKQLLEDRWKSLRQQLRERP 1404
L + QD + + R L +L++LE K+L+E R R L+
Sbjct: 640 RDRLEEEQEDAVQDGAR-VRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQR-- 696
Query: 1405 PLYQADEA 1412
+ QA++A
Sbjct: 697 DMLQAEKA 704
Score = 41.6 bits (96), Expect = 0.006
Identities = 83/396 (20%), Positives = 158/396 (39%), Gaps = 46/396 (11%)
Query: 1053 EEQAGQTDLEKIQFLLAQMVKRTIPPELQEQLKTVKTLAKEVWQEKAKVERLQRILEGEG 1112
++QA + E+ + AQ R L+E+ + V +E + R LEG+
Sbjct: 616 QQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKR 675
Query: 1113 NQEAGKELKAGELRLQLGVLRVTVADIEK-ELAELRESQDRGKAAMENSVS-----EASL 1166
+ A KEL L L+ + EK E+AE + G+ +E S++ EAS
Sbjct: 676 SVLA-KELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEAS- 733
Query: 1167 YLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAHTLAPGQIDPEATCPACSLDVSHQVST 1226
LQD L KL + ES+ L + Q++ E + + Q +T
Sbjct: 734 -LQDSLSKLSALNESLAQDKLDLNRL-----------VAQLEEEKSALQGRQRQAEQEAT 781
Query: 1227 LVR-RYEQLQDMVNSLAVSRPSKKAKL------QRQDEELLGRVQSAILQVQGDCEKLNI 1279
+ R E+L+++ V+R + L Q E+ L ++ Q+Q +L+
Sbjct: 782 VAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSR 841
Query: 1280 TTSNLIEDHRQKQKDIAMLYQGLEKL--EKEKANREHLEMEIDVKA--------DKSALA 1329
S ++ Q +++ + LE+ EKE +EH + + + A + A
Sbjct: 842 QLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATR 901
Query: 1330 TKVSRVQFDATTEQLNHMMQELVAKMSGQEQDWQKML---DRLLTEMDNKLDRLELDPVK 1386
++ + + + ++ + +L A+ E + Q +L + L E+ ++ K
Sbjct: 902 LRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEK 961
Query: 1387 QLLEDRWKSLRQQLRERPPLYQADEAAAMRRQLLAH 1422
L+ + + ER + A++R Q AH
Sbjct: 962 ASLDKELMAQKLVQAER------EAQASLREQRAAH 991
>gi|14149675 cleavage stimulation factor, 3' pre-RNA, subunit 2,
64kDa, tau variant [Homo sapiens]
Length = 616
Score = 60.5 bits (145), Expect = 1e-08
Identities = 110/414 (26%), Positives = 152/414 (36%), Gaps = 53/414 (12%)
Query: 477 PGTGQHDLVQS---GTGQGVLVQPGV----DQPGMVQPGRFQRALVQP------GAYQPG 523
PG Q V G G G+ P V P QP R V+ Q G
Sbjct: 202 PGKSQSVSVSGPGPGPGPGLCPGPNVLLNQQNPPAPQPQHLARRPVKDIPPLMQTPIQGG 261
Query: 524 LVQPGADQIDVVQPGADQHGLVQSGADQSDLAQPGAVQHGLVQPGVDQRGLAQPRADHQR 583
+ PG I PGA L GA Q L PG G V Q ++ PRA R
Sbjct: 262 IPAPGP--IPAAVPGAGPGSLTPGGAMQPQLGMPGV---GPVPLERGQVQMSDPRAPIPR 316
Query: 584 GLVPPGA-DQRGLV--QPGADQHGL---VQPGVDQHG-LAQPGEVQRSLVQPGIVQRGLV 636
G V PG RGL+ P + G V V+ G L P + G RG
Sbjct: 317 GPVTPGGLPPRGLLGDAPNDPRGGTLLSVTGEVEPRGYLGPPHQGPPMHHASGHDTRGPS 376
Query: 637 QPGAVQRGLVQPGAVQRGLVQPGVDQRGLVQPGAVQRG--LVQPGAVQHGLVQPGA-DQR 693
L P + P +DQRGL G R ++ A++ +++ ++R
Sbjct: 377 SHEMRGGPLGDPRLLIGEPRGPMIDQRGLPMDGRGGRDSRAMETRAMETEVLETRVMERR 436
Query: 694 GLVQPGVDQRGLVQPGVDQRGLVQPGM--DQRGLIQPGADQPGLVQPGAGQ--------- 742
G+ ++ RG+ G+D RGL G RG + G PG + GAG
Sbjct: 437 GMETCAMETRGMEARGMDARGLEMRGPVPSSRGPMTGGIQGPGPINIGAGGPPQGPRQVP 496
Query: 743 --LGMVQPGIGQQGMVQPQADPHGLVQPGAYPLGLVQPGAYLHDLSQSGTYPRGLVQPGM 800
G+ PG G QG G GA G GA + +S G +G G
Sbjct: 497 GISGVGNPGAGMQG-----TGIQGTGMQGAGIQGGGMQGAGIQGVSIQGGGIQGGGIQGA 551
Query: 801 DQYGLRQPGAYQPG--LIAPGTKLRGSSTFQADSTGFISVRPYQHGMVPPGREQ 852
+ G QP ++ PG + P + + + Q + + Q M+PP + Q
Sbjct: 552 SKQGGSQPSSFSPGQSQVTPQDQEKAALIMQV-----LQLTADQIAMLPPEQRQ 600
Score = 53.5 bits (127), Expect = 2e-06
Identities = 100/384 (26%), Positives = 139/384 (36%), Gaps = 47/384 (12%)
Query: 195 PVQQDLPLARDQPSSVPASQSQVHLRPDRRGLEPTGMNQPGLVPASTYPHGVVPLSMGQL 254
P+Q +P P++VP + L P G QP L P VPL GQ+
Sbjct: 257 PIQGGIPAPGPIPAAVPGAGPG--------SLTPGGAMQPQLGMPGVGP---VPLERGQV 305
Query: 255 GVPPPEMDDRELIPFVVDEQRMLPPSVPGRDQQGLELPSTDQHG-LVSVSAYQHGMTFPG 313
+ P R IP + P +P R G + P+ + G L+SV+ + G
Sbjct: 306 QMSDP----RAPIP----RGPVTPGGLPPRGLLG-DAPNDPRGGTLLSVTGEVEPRGYLG 356
Query: 314 TDQRSM---EPLGMDQRGCVISGMGQQGLVPPGIDQQGLTLPVVDQHGLVLPFTDQHGLV 370
+ G D RG M L P + P++DQ GL P + G
Sbjct: 357 PPHQGPPMHHASGHDTRGPSSHEMRGGPLGDPRLLIGEPRGPMIDQRGL--PMDGRGGRD 414
Query: 371 SPGLMPISADQQGFVQPSLEATGFIQPGTEQHDLIQSGRFQRALVQRGAYQPGLVQPGAD 430
S + + + + +E G E + G R L RG P G
Sbjct: 415 SRAMETRAMETEVLETRVMERRGMETCAMETRGMEARGMDARGLEMRG---PVPSSRGPM 471
Query: 431 QRGLVRPGMDQSGLAQPGADQRGLVWPGMDQSGLAQPGRDQHGLIQPGTGQHDL-VQSGT 489
G+ PG G P R + PG+ SG+ PG G GTG +Q G
Sbjct: 472 TGGIQGPGPINIGAGGPPQGPRQV--PGI--SGVGNPGAGMQGTGIQGTGMQGAGIQGGG 527
Query: 490 GQGVLVQPGVDQPGMVQPGRFQRALVQPGAYQPGLVQPGADQI------------DVVQP 537
QG +Q Q G +Q G Q A Q G+ QP PG Q+ V+Q
Sbjct: 528 MQGAGIQGVSIQGGGIQGGGIQGASKQGGS-QPSSFSPGQSQVTPQDQEKAALIMQVLQL 586
Query: 538 GADQHGLVQSGADQSDLAQPGAVQ 561
ADQ ++ QS L +Q
Sbjct: 587 TADQIAMLPPEQRQSILILKEQIQ 610
Score = 51.2 bits (121), Expect = 8e-06
Identities = 93/337 (27%), Positives = 132/337 (39%), Gaps = 47/337 (13%)
Query: 461 QSGLAQPGRDQHGLIQPGTGQHDLVQSGTGQGVLVQPGVDQPGMVQPGRFQ----RALVQ 516
Q G+ PG + PG G L G Q L PGV P ++ G+ Q RA +
Sbjct: 259 QGGIPAPGPIPAAV--PGAGPGSLTPGGAMQPQLGMPGVG-PVPLERGQVQMSDPRAPIP 315
Query: 517 PGAYQPGLVQPGADQIDVVQPGADQHGLVQSGADQSD----LAQP--GAVQHGLVQPGVD 570
G PG + P D P + G + S + + L P G H G D
Sbjct: 316 RGPVTPGGLPPRGLLGDA--PNDPRGGTLLSVTGEVEPRGYLGPPHQGPPMHHA--SGHD 371
Query: 571 QRGLAQPRADHQRGLVPPGADQRGLVQPGADQHGLVQPGVDQHGLAQPGEVQRS--LVQP 628
RG P + RG P D R L+ + G P +DQ GL G R ++
Sbjct: 372 TRG---PSSHEMRG--GPLGDPRLLI---GEPRG---PMIDQRGLPMDGRGGRDSRAMET 420
Query: 629 GIVQRGLVQPGAVQRGLVQPGAVQ-RGLVQPGVDQRGLVQPGAVQR-------GLVQPGA 680
++ +++ ++R ++ A++ RG+ G+D RGL G V G+ PG
Sbjct: 421 RAMETEVLETRVMERRGMETCAMETRGMEARGMDARGLEMRGPVPSSRGPMTGGIQGPGP 480
Query: 681 VQHGLVQPGADQRGLVQPGVDQRGLVQPGVDQRGLVQPGMDQRGLIQPGADQPGLVQPGA 740
+ G P R + PG+ G G+ G+ GM G IQ G Q GA
Sbjct: 481 INIGAGGPPQGPRQV--PGISGVGNPGAGMQGTGIQGTGMQGAG-IQGGGMQ------GA 531
Query: 741 GQLGMVQPGIGQQGMVQPQADPHGLVQPGAYPLGLVQ 777
G G+ G G QG A G QP ++ G Q
Sbjct: 532 GIQGVSIQGGGIQGGGIQGASKQGGSQPSSFSPGQSQ 568
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 58.5 bits (140), Expect = 5e-08
Identities = 94/435 (21%), Positives = 191/435 (43%), Gaps = 64/435 (14%)
Query: 997 RVLSEGSEVSSEVLSERRNSLRRMSSSFPTAVETFHLMGELSSLYVGLKESMKDLDEEQA 1056
R + E E+ E +++ R+ +++M++ GE L+E + E+A
Sbjct: 371 RQMHETLEMKEEEIAQLRSRIKQMTTQ-----------GE------ELREQKEK--SERA 411
Query: 1057 GQTDLEKIQFLL--AQMVKRTIPPELQEQLKTVKTLAKE----VWQEKAKVER-LQRILE 1109
+LEK + +R + E+ EQ+KT++ ++E + QE ++V++ + +++
Sbjct: 412 AFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMK 471
Query: 1110 GEGNQEAGKELKAGELRLQLGVLRVTVADIEKELAELRESQDRGKAAMENSVSEASLYLQ 1169
++ K K E L +T +K RE Q++ K A+E S SE Q
Sbjct: 472 KSSEEQIAKLQKLHEKELARKEQELT----KKLQTREREFQEQMKVALEKSQSEYLKISQ 527
Query: 1170 DQLDKLRMIIESMLTSSSTLLSMSM-----APHKAHTLAPGQIDPEATCPACSLDVSHQV 1224
++ + + +E + +L+ S +A T ++ E++ + +Q
Sbjct: 528 EKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQS 587
Query: 1225 STLVRRYEQLQDMVNS-LAVSRPSKKAKLQ----RQDEELLGRVQSAILQVQGDCEKLNI 1279
L E ++ N + V K +L+ +QD ++Q Q Q + EKL
Sbjct: 588 KDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLR- 646
Query: 1280 TTSNLIEDHRQKQKDIAMLYQGLEKLEKEKANREHLEMEIDVK-ADKSALATKVSRV--- 1335
++ KD +++Q E+ N + LE ++DVK + +L++++S V
Sbjct: 647 --EKCEQEKETLLKDKEIIFQA----HIEEMNEKTLE-KLDVKQTELESLSSELSEVLKA 699
Query: 1336 ------QFDATTEQLNHMMQELVAKMSGQEQDWQKMLDRLLTEMDNKLDRLE------LD 1383
+ +Q + M QEL AKM Q+ Q+ +D ++ E + + R E ++
Sbjct: 700 RHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQIN 759
Query: 1384 PVKQLLEDRWKSLRQ 1398
++ LL++R K L++
Sbjct: 760 QLELLLKERDKHLKE 774
Score = 44.7 bits (104), Expect = 8e-04
Identities = 88/379 (23%), Positives = 169/379 (44%), Gaps = 63/379 (16%)
Query: 1062 EKIQFLLAQMVKR-TIPPELQEQLKT----VKTLAKEVWQEKAKVERLQ-----RILEGE 1111
++I +L + VK+ T ELQEQLK V +LA++ + KA +E+L+ + E
Sbjct: 1092 KEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENT 1151
Query: 1112 GNQEAGKELK--AGELRLQLGVLRVTVADIEKELAELRESQDRGKAAMENSVSE---ASL 1166
QE ELK A E + ++ L + ++E L+ S ++ ++E+ E S
Sbjct: 1152 FLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSE 1211
Query: 1167 YLQDQLD----KLRMIIESM------LTSSSTLLSMSMAPHKAH------------TLAP 1204
L QLD K ++E+ ++SS T +S H H T
Sbjct: 1212 ELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTV 1271
Query: 1205 GQIDP---EATCPACSLDVSHQVSTLVRRYEQLQDMVNSLAV---SRPSKKAKLQRQ--- 1255
+++ + T +L++S Q +T + E+ ++ + S+ S ++K LQ++
Sbjct: 1272 SELEAQLRQLTEEQNTLNISFQQAT--HQLEEKENQIKSMKADIESLVTEKEALQKEGGN 1329
Query: 1256 DEELLGRVQSAILQVQGD-CEKLNITTSNLIEDHRQKQKDIAMLYQGLEKLEKEKANREH 1314
++ +S I Q++ + E +N T + E+ ++K+ +I+ L + L L + N
Sbjct: 1330 QQQAASEKESCITQLKKELSENINAVTL-MKEELKEKKVEISSLSKQLTDLNVQLQNSIS 1388
Query: 1315 L-EMEIDVKA-------DKSALATKVSRVQFDATT---EQLNHMMQELVAKMSGQEQDWQ 1363
L E E + + +K L +V + F T E+++ + E V S + +W+
Sbjct: 1389 LSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISAL--EQVDDWSNKFSEWK 1446
Query: 1364 KMLDRLLTEMDNKLDRLEL 1382
K T+ N + L++
Sbjct: 1447 KKAQSRFTQHQNTVKELQI 1465
>gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]
Length = 1219
Score = 57.0 bits (136), Expect = 1e-07
Identities = 82/411 (19%), Positives = 156/411 (37%), Gaps = 47/411 (11%)
Query: 982 PGQDVTLFRSP--DSVDRVLSEGSEVSSEVLSERRNSLRRMSSSFPTAVETFHLMGELSS 1039
P VT+ S ++ R++ E + E+L E+ N + + +E E S+
Sbjct: 552 PSMSVTMETSMIMSNIQRIIQENERLKQEIL-EKSNRIEEQNDKISELIERNQRYVEQSN 610
Query: 1040 LYVGLK--------------------ESMKDLDEEQAGQTDLEKIQF-LLAQMVKRT-IP 1077
L + + E K +E A + +Q + A K T +
Sbjct: 611 LMMEKRNNSLQTATENTQARVLHAEQEKAKVTEELAAATAQVSHLQLKMTAHQKKETELQ 670
Query: 1078 PELQEQLKTVKTLAKEVWQEKAKVERLQRILE-------GEGNQEAGKELKAGELRLQLG 1130
+L E LK L ++ + +AK+ LQ E E ELK L +L
Sbjct: 671 MQLTESLKETDLLRGQLTKVQAKLSELQETSEQAQSKFKSEKQNRKQLELKVTSLEEELT 730
Query: 1131 VLRVTVADIEKELAELRESQDRGKAAMENSVSEASLYLQDQLDKLRMIIESMLTSSSTLL 1190
LRV +EK L+E ++ + ++ E + E Q++LDKLR +++ S+
Sbjct: 731 DLRVEKESLEKNLSERKKKSAQERSQAEEEIDEIRKSYQEELDKLRQLLKKTRVSTDQAA 790
Query: 1191 SMSMAPHKAHTLAPGQIDPEATCPACSLDVSHQVSTLVRRYEQLQDMVNSLAVSRPSKKA 1250
+ ++ +A Q EA C + + +D V K
Sbjct: 791 AEQLSLVQAEL----QTQWEAKCEHLLASAKDEHLQQYQEVCAQRDAYQQKLVQLQEKCL 846
Query: 1251 KLQRQDEELLGRVQSAILQVQGDCEKLNITTSNLIEDHRQKQKDIAMLYQGLEKLEKEKA 1310
LQ Q L + + I +++ + +++ + + + +K + ++Q L
Sbjct: 847 ALQAQITALTKQNEQHIKELEKNKSQMSGVEAAASDPSEKVKKIMNQVFQSL-------- 898
Query: 1311 NREHLEMEIDVKADKSALATKVSRVQFDATTEQLNHMMQELVAKMSGQEQD 1361
R E+E ++ L T ++ ++ T + LN QE S +E++
Sbjct: 899 -RREFELEESYNG-RTILGTIMNTIKM-VTLQLLNQQEQEKEESSSEEEEE 946
Score = 33.1 bits (74), Expect = 2.3
Identities = 51/254 (20%), Positives = 101/254 (39%), Gaps = 30/254 (11%)
Query: 1157 MENSVSEASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAHTLAPGQIDPEATCPAC 1216
++ + E S +++Q DK+ +IE S M + ++L + +A
Sbjct: 577 LKQEILEKSNRIEEQNDKISELIER--NQRYVEQSNLMMEKRNNSLQTATENTQARVLHA 634
Query: 1217 SLDVSHQVSTLVRRYEQLQDMVNSLAVSRPSKKAKLQRQDEELLGRVQSAILQVQGDCEK 1276
+ + L Q+ + + + K+ +LQ Q E L ++G K
Sbjct: 635 EQEKAKVTEELAAATAQVSHLQLKMTAHQ-KKETELQMQLTESLKETDL----LRGQLTK 689
Query: 1277 LNITTSNLIEDHRQKQKDIAMLYQGLEKLEKEKANREHLEMEIDVKADKSALATKVSRVQ 1336
+ S L E Q Q K + EK NR+ LE+++ ++L +++ ++
Sbjct: 690 VQAKLSELQETSEQAQS----------KFKSEKQNRKQLELKV------TSLEEELTDLR 733
Query: 1337 FDATTEQLNHMMQELVAKMSGQEQDWQKMLDRLLTEMDNKLDRLELDPVKQLLEDRWKSL 1396
+ E L + E K + + ++ +D + +LD+L +QLL+ S
Sbjct: 734 VEK--ESLEKNLSERKKKSAQERSQAEEEIDEIRKSYQEELDKL-----RQLLKKTRVST 786
Query: 1397 RQQLRERPPLYQAD 1410
Q E+ L QA+
Sbjct: 787 DQAAAEQLSLVQAE 800
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 56.2 bits (134), Expect = 3e-07
Identities = 155/734 (21%), Positives = 283/734 (38%), Gaps = 92/734 (12%)
Query: 993 DSVDRVLSEG---SEVSSEVLSERRNSLRRMSSSFPTAV-ETFHLMGELSSLYVGLK--- 1045
+ + + LSE E ++ L + +R AV E L+ E ++L V L+
Sbjct: 690 EEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVE 749
Query: 1046 ESMKDLDEEQAGQTD----LEKIQFLLAQM--VKRTIPPELQEQLKTVKTLAKEVWQEKA 1099
+DL E+ G + LE F Q V +L+ Q++TV T AKEV Q +
Sbjct: 750 RDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTV-TQAKEVIQGEV 808
Query: 1100 KVERLQRILE-GEGNQE---AGKELKAGELRLQLGVLRVTVADIEKELAELRESQDRGKA 1155
+ +L+ E + QE A ++L E + + + A EKE+ +LRE ++ ++
Sbjct: 809 RCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAH-EKEVNQLREKWEKERS 867
Query: 1156 AMENSVSEASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAHTLAPGQIDPEATCPA 1215
+ +++A L+ + +L M ++ T + + A Q+ E
Sbjct: 868 WHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKER 927
Query: 1216 CSLDVSHQVSTLVRRYEQLQDMVNSLAVSRPSKKAK----------LQRQDEELLGRVQS 1265
SL + TL++ ++L D L R K + LQ Q +E ++
Sbjct: 928 VSL-----LETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKE 982
Query: 1266 AILQVQGDCEKLNITTSNLIEDHRQKQKDIAMLYQGL---------------EKL-EKEK 1309
A Q + D L +S+L++D QK + L L EKL E ++
Sbjct: 983 AARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQE 1042
Query: 1310 ANREHLEMEIDVKADKSALATKVSRV----QFDATTEQLNHMMQELVAKMSGQEQDWQKM 1365
NR E+E + + +L K R+ + D+ +Q +++ + + G++++
Sbjct: 1043 YNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQ 1102
Query: 1366 LDRLLTEMDNK-----------LDRLELDPV--KQLLEDRW----KSLRQQLRERPPLYQ 1408
++ L E+ K L+ LE + +QL W K+ + QLR R Q
Sbjct: 1103 MELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQ 1162
Query: 1409 ADEAAAMRR---QLLAHFHCLSCDRPLETPVTGHAIPVTPAGPGLPGHHSIRPYTVFELE 1465
+ AA ++ Q A S L+ + V + P L G P +V+ LE
Sbjct: 1163 LEALAAEQQPGNQAQAQAQLASLYSALQQALGS----VCESRPELSGGGDSAP-SVWGLE 1217
Query: 1466 QVRQHSRNL--------KLGSAFPRGDLAQMEQSVGRLRSMHSKMLMNIEKVQIHFGGST 1517
+ +R+L L + L ++ Q + + + + ++K++ +
Sbjct: 1218 PDQNGARSLFKRGPLLTALSAEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTE 1277
Query: 1518 KASSQIIRELLHAQCLGSPCYKRVTDMADYTYSTVPRRCGGSHTLTYPYHRSRPQHLPR- 1576
SQ+ EL Q S + + S T+ R R L R
Sbjct: 1278 AEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRM 1337
Query: 1577 -GLYPTEEIQIAMKHDEVDILGLDGHIYKGRMDTRLPGILRKD---SSGTSKRKSQQPRP 1632
E +Q A ++ + L + + R GIL +D + K K+++
Sbjct: 1338 EAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVES 1397
Query: 1633 HVHRPPSLSSNGQL 1646
R +L G+L
Sbjct: 1398 ERERAQALQEQGEL 1411
Score = 47.0 bits (110), Expect = 2e-04
Identities = 66/331 (19%), Positives = 142/331 (42%), Gaps = 51/331 (15%)
Query: 1080 LQEQLKTVKTLAKEVWQEKAKV----ERLQRILEGEGNQEAGKELKAGELRLQLGVLRVT 1135
L++Q++ ++ + EK++V + LQR L +++ E K L +L L T
Sbjct: 1262 LRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHET 1321
Query: 1136 VADIEKEL--AELRESQDRGKAAMENSVSEASLYLQDQLDKLRMIIESMLTSSSTLLSMS 1193
+A ++ L AEL+ + +G+ + + E LT+ L +
Sbjct: 1322 MASLQSRLRRAELQRMEAQGERELLQAAKEN------------------LTAQVEHLQAA 1363
Query: 1194 MAPHKAHTLAPGQIDPEATCPACSLDVSHQVSTLVRRYEQLQDMVNSLAVSR-------- 1245
+ +A A G ++ + +L + ++ R Q L V++
Sbjct: 1364 VVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENL 1423
Query: 1246 ---PSKKAKLQRQDEELLGRVQSAILQVQGDCEKLNITTSNLIEDHRQKQKDIAMLYQGL 1302
A+ + + E L G++Q L+ Q + +K + +L D +++ +++ + + +
Sbjct: 1424 ALLTQTLAEREEEVETLRGQIQE--LEKQREMQKAALELLSL--DLKKRNQEVDLQQEQI 1479
Query: 1303 EKLEKEKANREHLEMEIDVKADK-SALATKVSRVQFDATTEQ--LNHMMQEL------VA 1353
++LEK ++ EHL M + + K + ++ ++ D T++ L H + EL +
Sbjct: 1480 QELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIE 1539
Query: 1354 KMSGQEQDWQKM---LDRLLTEMDNKLDRLE 1381
GQ QD +K L+ L E++ ++E
Sbjct: 1540 SQRGQVQDLKKQLVTLECLALELEENHHKME 1570
Score = 43.5 bits (101), Expect = 0.002
Identities = 90/428 (21%), Positives = 165/428 (38%), Gaps = 88/428 (20%)
Query: 1045 KESMKDLDEEQAGQT-----DLEKIQFLLAQM-----VKRTIPPELQEQLK--------- 1085
KE ++ L++++ QT DLE+I+ L + +R + E E+ K
Sbjct: 1664 KERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGS 1723
Query: 1086 ------TVKTLAKEVWQEKAKVERLQRILEGEGNQEAGKELKAGELRLQLGVLRVTVADI 1139
++ KEV ++ + LQ + + Q G K GE L L + +
Sbjct: 1724 LEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVL 1783
Query: 1140 EKELAELRESQDRGKAAMENSVSEASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKA 1199
+++L E RE + + ++++ + EA L + +L + + +
Sbjct: 1784 QQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQG------------ 1831
Query: 1200 HTLAPGQIDPEATCPACSLDVSHQVSTLVRRYEQLQDMVNSLAVSRPSKKAKLQRQDEEL 1259
++ +A +L+ +H TL R+ +LQD K + +R +EEL
Sbjct: 1832 ---QEERVKEKADALQGALEQAHM--TLKERHGELQD-----------HKEQARRLEEEL 1875
Query: 1260 L--GRVQSAILQVQGDCEKLNITTSNLIEDHRQKQKDIAMLYQGLEKLEKEKANREHLE- 1316
GR A+ +V GD E Q++ +A+ Q E+ ++ + L+
Sbjct: 1876 AVEGRRVQALEEVLGDLR---------AESREQEKALLALQQQCAEQAQEHEVETRALQD 1926
Query: 1317 ---------MEIDVKADKSALATKVSRVQFDAT---TEQLNHMMQELVAKMSGQEQDW-- 1362
E D + + ++ SR Q +A E L + + A + G+EQ
Sbjct: 1927 SWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLE 1986
Query: 1363 QKMLDRLLTEMDNKLDRLELDPVKQLLEDRWKSLR--------QQLRERPPLYQADEAAA 1414
Q L R L E + LD + ++LR Q LR + + Q +A A
Sbjct: 1987 QAELSRSL-EASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALA 2045
Query: 1415 MRRQLLAH 1422
R + L H
Sbjct: 2046 QRDEELRH 2053
Score = 40.4 bits (93), Expect = 0.014
Identities = 80/354 (22%), Positives = 144/354 (40%), Gaps = 51/354 (14%)
Query: 1052 DEEQAGQTDLEKIQFLLAQMVKRTIPPELQEQLKTVKTLAKEVWQEKAKVERLQRILEGE 1111
D++ Q D++++Q LAQ + + +EQL EK+ +R+Q + E
Sbjct: 2028 DQDLRYQEDVQQLQQALAQRDEELRHQQEREQLL-----------EKSLAQRVQENMIQE 2076
Query: 1112 GNQEAGKELKAGELR---LQLGVLRVTVADIEKELAELRESQDRGK-AAMENSVSEASLY 1167
Q G+E + E+R + L++T+A E+E+ ELRE+Q R A+ +S + +
Sbjct: 2077 -KQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPME 2135
Query: 1168 LQD-QLDKLRMIIESMLTSSSTLLSMSMA-----PHKAHTLAPGQIDPEATCPACSLDVS 1221
Q +LD L ++ L L + A KA LA +A+ +
Sbjct: 2136 EQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAM 2195
Query: 1222 HQVSTLVRRYEQLQDMVNSLAVSR------------PSKKAKLQRQDEE--LLGRVQSAI 1267
++++ R + Q + + L ++R + A+L + E+ LG V
Sbjct: 2196 FLQASVLERDSEQQRLQDELELTRRALEKERLHSPGATSTAELGSRGEQGVQLGEVSGVE 2255
Query: 1268 LQVQGD----------CEKLNITTSNLIEDHRQKQKDIAMLYQGLEKLEKEKANREHLEM 1317
+ D E L + L D + Q+ L LE++E+E R L+
Sbjct: 2256 AEPSPDGMEKQSWRQRLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQVERE---RRKLKR 2312
Query: 1318 EIDVKADKSALATKVSRVQFDATTEQLNHMMQELVAKMSGQEQDWQKMLDRLLT 1371
E A +L ++S+ + T+Q + AK + Q +L LT
Sbjct: 2313 EAMRAAQAGSL--EISKATASSPTQQDGRGQKNSDAKCVAELQKEVVLLQAQLT 2364
Score = 36.6 bits (83), Expect = 0.21
Identities = 71/390 (18%), Positives = 150/390 (38%), Gaps = 64/390 (16%)
Query: 1037 LSSLYVGLKESMKDLDEEQAGQTDLEKIQFLLAQMVKRTIPPELQEQLKTVKTLAKEVWQ 1096
L+ L + L+E ++L + + DLE +LA+ ELQE+ + VK+
Sbjct: 1590 LTHLTLDLEERSQELQAQSSQIHDLESHSTVLAR--------ELQERDQEVKS------- 1634
Query: 1097 EKAKVERLQRILEGEGNQEAGKELKAGELRLQLGVLRVTVADIEKELAELRESQDRGKAA 1156
++ ++E LQR + ++L+ + L L R+ V L + + R
Sbjct: 1635 QREQIEELQR-----QKEHLTQDLERRDQELMLQKERIQV---------LEDQRTRQTKI 1680
Query: 1157 MENSVSEASLYLQD---QLDKLRMIIESMLTSSSTLLSMSMAPHKAHTLAPGQIDPEATC 1213
+E + + L L++ +L R +++ + L + E C
Sbjct: 1681 LEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVEC 1740
Query: 1214 PACSLDVSHQVSTLVRRYEQLQDMVNSLAVSRPSKKAKLQRQDEELLGRVQSAILQVQGD 1273
+ L +QL+ + L L ++++E++ Q Q+Q
Sbjct: 1741 Q------QEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQ----QLQEA 1790
Query: 1274 CEKLNITTSNLIEDHRQKQKDIAMLYQGLEKLEKEKANREHLEMEIDVKAD-------KS 1326
E+ + +L + Q+ +A Q LE L++E+ + E + KAD ++
Sbjct: 1791 REQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQA 1850
Query: 1327 ALATKVSRVQFDATTEQLNHM-------------MQELVAKMSGQEQDWQKMLDRLLTEM 1373
+ K + EQ + ++E++ + + ++ +K L L +
Sbjct: 1851 HMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQC 1910
Query: 1374 DNKLDRLELDPVKQLLEDRWKSLRQQLRER 1403
+ E++ + L+D W + L+ER
Sbjct: 1911 AEQAQEHEVE--TRALQDSWLQAQAVLKER 1938
>gi|21450705 leucine rich repeat containing 45 [Homo sapiens]
Length = 670
Score = 55.5 bits (132), Expect = 4e-07
Identities = 85/387 (21%), Positives = 169/387 (43%), Gaps = 42/387 (10%)
Query: 1029 ETFHLMGELSSLYVGLKESMKDLDEEQAGQTDLEKIQFLLAQMVKRTIPPELQEQLKTVK 1088
E HL E S ++ L E++ EE A + + +LQE L
Sbjct: 247 EVQHLREEKSKQFLDLMETIDKQREEMAKSSRASAARV-----------GQLQEALNERH 295
Query: 1089 TLAKEVWQEKAKVERLQRIL--EGEGNQEAGKELKAGELRLQLGVLRVTVADIEKELAEL 1146
++ + KAK++ + L + Q+ G+ L E QL + + +++ E E
Sbjct: 296 SIINAL---KAKLQMTEAALALSEQKAQDLGELLATAEQE-QLSLSQRQAKELKLEQQEA 351
Query: 1147 RESQDRGKAAMENSVSEASLYLQDQLDKL----RMIIESMLTSSSTLLSMSMAPHKAHTL 1202
E + + + ++ +E +L LQ+Q+D+L R E + + + SMS
Sbjct: 352 AERESKLLRDL-SAANEKNLLLQNQVDELERKFRCQQEQLFQTRQEMTSMSAELKMRAIQ 410
Query: 1203 APGQIDPEATCPACSLDVSHQVSTLVRRYEQLQDMVNSLAVSRPSKKAKLQRQD------ 1256
A ++D E SL+ S + R ++++ M L S + + ++QR +
Sbjct: 411 AEERLDMEKRRCRQSLEDSESL-----RIKEVEHMTRHLEESEKAMQERVQRLEAARLSL 465
Query: 1257 EELLGRVQSAILQVQGDCEKLNITTSNLIEDHRQKQKDIAMLYQGLEKLEKEKANREHLE 1316
EE L RV++A L +G E+ I + + ++Q+ +A L L L + + +
Sbjct: 466 EEELSRVKAAALSERGQAEEELIKAKS--QARLEEQQRLAHLEDKLRLLAQARDEAQGAC 523
Query: 1317 MEIDVKADKSALATKVSRV-QFDATTEQLNHMMQELVAKMSGQEQDWQKMLDRLLTEMDN 1375
++ K +A +RV Q E L ++EL ++S ++Q+ + R+ E+
Sbjct: 524 LQ-----QKQVVAEAQTRVSQLGLQVEGLRRRLEELQQELSLKDQERVAEVSRVRVELQE 578
Query: 1376 KLDRLELD-PVKQLLEDRWKSLRQQLR 1401
+ RL+ + ++ L ++ +L +QL+
Sbjct: 579 QNGRLQAELAAQEALREKAAALERQLK 605
Score = 37.7 bits (86), Expect = 0.094
Identities = 67/278 (24%), Positives = 117/278 (42%), Gaps = 47/278 (16%)
Query: 1053 EEQAGQTDLEKIQFLLAQMVKRTIPPELQEQLKTVKTLAKEVWQEKA-----KVERLQRI 1107
+EQ QT E + A++ R I E E+L K ++ ++ +VE + R
Sbjct: 387 QEQLFQTRQEMTS-MSAELKMRAIQAE--ERLDMEKRRCRQSLEDSESLRIKEVEHMTRH 443
Query: 1108 LEG--EGNQEAGKELKAGELRLQLGVLRVTVADIEKELAELRESQDRGKAAME--NSVSE 1163
LE + QE + L+A L L+ + RV A + +RG+A E + S+
Sbjct: 444 LEESEKAMQERVQRLEAARLSLEEELSRVKAAALS----------ERGQAEEELIKAKSQ 493
Query: 1164 ASLYLQDQL----DKLRMIIESMLTSSSTLLSMSMAPHKAHTLAPGQIDPEATCPACSLD 1219
A L Q +L DKLR++ ++ + L +A T
Sbjct: 494 ARLEEQQRLAHLEDKLRLLAQARDEAQGACLQQKQVVAEAQTRVS--------------Q 539
Query: 1220 VSHQVSTLVRRYEQLQDMVNSLAVSRPSKKAKLQRQDEELLGRVQSAILQVQGDCEK--- 1276
+ QV L RR E+LQ ++ R ++ ++++ + +E GR+Q+ + + EK
Sbjct: 540 LGLQVEGLRRRLEELQQELSLKDQERVAEVSRVRVELQEQNGRLQAELAAQEALREKAAA 599
Query: 1277 LNITTSNLIEDHRQ----KQKDIAMLYQGLEKLEKEKA 1310
L + DHR+ ++ + A L + L E E A
Sbjct: 600 LERQLKVMASDHREALLDRESENASLREKLRLREAEIA 637
>gi|4557493 cleavage stimulation factor subunit 2 [Homo sapiens]
Length = 577
Score = 55.1 bits (131), Expect = 6e-07
Identities = 88/343 (25%), Positives = 125/343 (36%), Gaps = 43/343 (12%)
Query: 521 QPGLVQPGADQIDVVQPGADQHGLVQSGADQSDLAQPGAVQHGLVQPGVDQRGLAQPRAD 580
Q G+ PG V PG L G Q+ + PG+ G V Q + PRA
Sbjct: 251 QGGVPAPGQMPAAVTGPGPGS--LAPGGGMQAQVGMPGS---GPVSMERGQVPMQDPRAA 305
Query: 581 HQRGLVPPGADQ-RGLV--QPGADQHGL---VQPGVDQHG-LAQPGEVQRSLVQPGIVQR 633
QRG +P RGL+ P + G V V+ G L P + PG R
Sbjct: 306 MQRGSLPANVPTPRGLLGDAPNDPRGGTLLSVTGEVEPRGYLGPPHQGPPMHHVPGHESR 365
Query: 634 GLVQPGAVQRG--LVQPGAVQRGLVQPGVDQRGLVQPGAVQRGLVQPGAVQHGLVQPGAD 691
G P RG L +P + P +DQRG P RG G D
Sbjct: 366 G--PPPHELRGGPLPEPRPLMAEPRGPMLDQRG---PPLDGRG--------------GRD 406
Query: 692 QRGLVQPGVDQRGLVQPGVDQRGLVQPGMDQRGLIQPGADQPGLVQPGAGQLGMVQPGIG 751
RG+ G++ R + G+D RGL M+ R + + + GM G+
Sbjct: 407 PRGIDARGMEARAMEARGLDARGLEARAMEARAMEARAMEARAMEARAMEVRGMEARGMD 466
Query: 752 QQGMVQPQADPHGLVQPGAYPLGLVQPGAYLHDLSQSGTYPRGLVQPGMDQYGLRQPGAY 811
+G P P G + G + GA + S+ +G G G QPG +
Sbjct: 467 TRG---PVPGPRGPIPSGMQGPSPINMGAVVPQGSRQVPVMQGTGMQGASIQGGSQPGGF 523
Query: 812 QPG--LIAPGTKLRGSSTFQADSTGFISVRPYQHGMVPPGREQ 852
PG + P + + Q + + Q M+PP + Q
Sbjct: 524 SPGQNQVTPQDHEKAALIMQV-----LQLTADQIAMLPPEQRQ 561
Score = 52.4 bits (124), Expect = 4e-06
Identities = 84/298 (28%), Positives = 115/298 (38%), Gaps = 46/298 (15%)
Query: 501 QPGMVQPGRFQRALVQPGAYQPGLVQPGAD-QIDVVQPGADQHGLVQSGADQSDLAQP-G 558
Q G+ PG+ A+ PG PG + PG Q V PG+ G V Q + P
Sbjct: 251 QGGVPAPGQMPAAVTGPG---PGSLAPGGGMQAQVGMPGS---GPVSMERGQVPMQDPRA 304
Query: 559 AVQHGLVQPGVDQ-RGLAQPRADHQRG----LVPPGADQRGLVQP---GADQHGLVQPGV 610
A+Q G + V RGL + RG V + RG + P G H + PG
Sbjct: 305 AMQRGSLPANVPTPRGLLGDAPNDPRGGTLLSVTGEVEPRGYLGPPHQGPPMHHV--PGH 362
Query: 611 DQHGLAQPGEVQRS-LVQPGIVQRGLVQPGAVQRGLVQPGAVQRGLVQPGVDQRGLVQPG 669
+ G P E++ L +P + P QRG P RG G D RG+ G
Sbjct: 363 ESRG-PPPHELRGGPLPEPRPLMAEPRGPMLDQRG---PPLDGRG----GRDPRGIDARG 414
Query: 670 AVQRGLVQPGAVQHGLVQPGADQRGLVQPGVDQRGLVQPGVDQRGLVQPGMDQRGLIQPG 729
R + G GL + R + ++ R + ++ RG+ GMD RG + PG
Sbjct: 415 MEARAMEARGLDARGLEARAMEARAMEARAMEARAMEARAMEVRGMEARGMDTRGPV-PG 473
Query: 730 ADQP---GLVQPGAGQLGMVQP----------GIGQQGMVQPQADPHGLVQPGAYPLG 774
P G+ P +G V P G G QG A G QPG + G
Sbjct: 474 PRGPIPSGMQGPSPINMGAVVPQGSRQVPVMQGTGMQG-----ASIQGGSQPGGFSPG 526
Score = 49.7 bits (117), Expect = 2e-05
Identities = 83/335 (24%), Positives = 118/335 (35%), Gaps = 64/335 (19%)
Query: 101 PSIEQALDSASGLGPDRTASGSGGTAH---PSDGVSSREQSKVPSGTGRQQQPRARDEAG 157
P+ Q + +G GP A G G A P G S E+ +VP Q PRA + G
Sbjct: 255 PAPGQMPAAVTGPGPGSLAPGGGMQAQVGMPGSGPVSMERGQVP-----MQDPRAAMQRG 309
Query: 158 VPRLHQSSTFQFKSDSDRHRSREKLTSTQPRRNARPGPVQQDLPLARDQPSSVPASQSQV 217
L + P G D P S + +
Sbjct: 310 -----------------------SLPANVPTPRGLLGDAPND-PRGGTLLSVTGEVEPRG 345
Query: 218 HLRPDRRGLEPTGMNQPGLVPASTYPHGVVPLSMGQLGVPPPEMDDRELIPFVVDEQRML 277
+L P +G P + PG PH L G L P P M +
Sbjct: 346 YLGPPHQG--PPMHHVPGHESRGPPPH---ELRGGPLPEPRPLMAE-------------- 386
Query: 278 PPSVPGRDQQGLELPSTDQHGLVSVSAYQHGMTFPGTDQRSMEPLGMDQRGCVISGMGQQ 337
P P DQ+G P D G G+ G + R+ME G+D RG M +
Sbjct: 387 -PRGPMLDQRG---PPLDGRG----GRDPRGIDARGMEARAMEARGLDARGLEARAMEAR 438
Query: 338 GLVPPGIDQQGLTLPVVDQHGLVLPFTDQHGLVSPGLMPISADQQGFVQPSLEATGFIQP 397
+ ++ + + ++ G+ D G V PI + QG PS G + P
Sbjct: 439 AMEARAMEARAMEARAMEVRGMEARGMDTRGPVPGPRGPIPSGMQG---PSPINMGAVVP 495
Query: 398 -GTEQHDLIQSGRFQRALVQRGAYQPGLVQPGADQ 431
G+ Q ++Q Q A +Q G+ QPG PG +Q
Sbjct: 496 QGSRQVPVMQGTGMQGASIQGGS-QPGGFSPGQNQ 529
Score = 44.3 bits (103), Expect = 0.001
Identities = 90/368 (24%), Positives = 133/368 (36%), Gaps = 73/368 (19%)
Query: 225 GLEPTGMNQPGLVPASTYPHGVVPLSMGQLGVPPPEMDDRELI---PFVVDEQRMLPPSV 281
G P + PG P S P G + +G G P M+ ++ P ++ LP +V
Sbjct: 258 GQMPAAVTGPG--PGSLAPGGGMQAQVGMPGSGPVSMERGQVPMQDPRAAMQRGSLPANV 315
Query: 282 PGRDQQGL--ELPSTDQHG-LVSVSAYQHGMTFPGTDQRSMEPLGMDQRGCVISGMGQQG 338
P +GL + P+ + G L+SV+ +EP G
Sbjct: 316 P--TPRGLLGDAPNDPRGGTLLSVTG-------------EVEPRGY-------------- 346
Query: 339 LVPPGIDQQGLTLPVVDQH-GLVLPFTDQHGLVSPGLMPISADQQGFVQPSLEATGFIQP 397
L PP QG + V H P + G P P+ A+ +G P L+ G
Sbjct: 347 LGPP---HQGPPMHHVPGHESRGPPPHELRGGPLPEPRPLMAEPRG---PMLDQRGPPLD 400
Query: 398 GTEQHDLIQSGRFQRALVQRGAYQPGLVQPGADQRGLVRPGMDQSGLAQPGADQRGLVWP 457
G + GR R + RG + G D RGL M+ + + R +
Sbjct: 401 G-------RGGRDPRGIDARGMEARAMEARGLDARGLEARAMEARAMEARAMEARAMEAR 453
Query: 458 GMDQSGLAQPGRDQHGLIQPGTGQHDLVQSG------TGQGVLVQPGVDQPGMVQPGRFQ 511
M+ G+ G D G P G + SG G +V G Q ++Q Q
Sbjct: 454 AMEVRGMEARGMDTRG---PVPGPRGPIPSGMQGPSPINMGAVVPQGSRQVPVMQGTGMQ 510
Query: 512 RALVQPGAYQPGLVQPGADQI------------DVVQPGADQHGLVQSGADQSDLAQPGA 559
A +Q G+ QPG PG +Q+ V+Q ADQ ++ QS L
Sbjct: 511 GASIQGGS-QPGGFSPGQNQVTPQDHEKAALIMQVLQLTADQIAMLPPEQRQSILILKEQ 569
Query: 560 VQHGLVQP 567
+Q P
Sbjct: 570 IQKSTGAP 577
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 54.3 bits (129), Expect = 1e-06
Identities = 93/456 (20%), Positives = 185/456 (40%), Gaps = 65/456 (14%)
Query: 1018 RRMSSSFPTAVETFHLMGELSSLYVGLKESMKDLDEEQAGQT----------DLEKIQFL 1067
R++ + + T L+ LK+ + +++ + A Q+ + E + L
Sbjct: 878 RQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDL 937
Query: 1068 LAQMVKRTIPPELQEQLKTVKTLAKEVWQEKAKVERLQRILEGEGNQEAGKELKAGELRL 1127
++Q+ R ++ + + +KT V Q +A V L+ L E Q + K E+RL
Sbjct: 938 VSQL--RQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKE-KQVTEEVRKNIEVRL 994
Query: 1128 QLGV-----LRVTVADIEKELAELRESQDRGKAAMENSVSEASLYLQDQLDKLRMIIESM 1182
+ L + ++EKE EL++ + R +ME +SE L+ L ++ ++
Sbjct: 995 KESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSE----LKKTLSSVQNEVQEA 1050
Query: 1183 LTSSSTLLSMSMAPH-------KAHTLAPGQIDPEATCPACSLD----VSHQVSTLVRRY 1231
L +ST LS K A + + E A ++ QVS +
Sbjct: 1051 LQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVR 1110
Query: 1232 EQLQDMVNSLAVSRPSKKAKLQRQDEELLGRVQSAILQVQGDCEKLNITTSNLIEDHRQK 1291
+ L++ KA + ++ L V + + + D EK N L+ D +K
Sbjct: 1111 QHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCE-DLEKQN----RLLHDQIEK 1165
Query: 1292 QKD--IAMLYQGLE------KLEKEKANREHLEMEIDVKADKSALATK-----VSRVQFD 1338
D +A + +G++ E+ K+ + LE+ ++ +K T+ V +++
Sbjct: 1166 LSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYR 1225
Query: 1339 ATTEQLNHMMQEL-------------VAKMSGQEQDWQKMLDRLLTEMD-NKLDRLELDP 1384
E L +QEL AK Q ++ K + + M+ NK+ R E +
Sbjct: 1226 QRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKER 1285
Query: 1385 VKQLLEDRWKSLRQQLRERPPLYQADEAAAMRRQLL 1420
++Q L+ +R+ + PL +A+ + + +L
Sbjct: 1286 LEQDLQQMQAKVRKLELDILPLQEANAELSEKSGML 1321
Score = 40.4 bits (93), Expect = 0.014
Identities = 81/450 (18%), Positives = 173/450 (38%), Gaps = 80/450 (17%)
Query: 1004 EVSSEVLSERRNSLRRMSSSFPTAVETF----HLMGELSSLYVGLKESMKDLDEEQAGQT 1059
E+ L E ++SL +T LM + ++ V ++ + +E++ +
Sbjct: 1229 ELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQ 1288
Query: 1060 DLEKIQFLLAQMVKRTIP-----PELQEQLKTV----KTLAKEVWQEKAKVERLQRILEG 1110
DL+++Q + ++ +P EL E+ + K L ++V + KA+ + L +
Sbjct: 1289 DLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKD 1348
Query: 1111 EGNQEAGKELKAGELRLQLGVLRVTVADIEKELAELRESQDRGKAAMENSVSEASLYLQD 1170
+E K L E+ + + + +E+ L+ R A++ N+ Q+
Sbjct: 1349 PDTEEYRKLLSEKEVHTK------RIQQLTEEIGRLKAEIARSNASLTNN--------QN 1394
Query: 1171 QLDKLRMIIESMLTSSSTLLSMSMAPHKAHTLAPGQIDPEATCPACSLDVSHQVSTLVR- 1229
+ L+ + + T T+ Q D +A +D+ +V T+ +
Sbjct: 1395 LIQSLKEDLNKVRTEKETI----------------QKDLDAKI----IDIQEKVKTITQV 1434
Query: 1230 ---------RYEQLQDMVNSLAVSRPSKKAKLQRQD---------EELLGRVQSAILQVQ 1271
+YE+L+ + + + Q Q +E L + ++ ++
Sbjct: 1435 KKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLE 1494
Query: 1272 GDCEKLNITTS-------NLIEDHRQKQKDIAMLYQGLEKLEKEKANREHLEMEIDVKAD 1324
E L T S NL E Q Q +++ L Q L+ ++ E + K
Sbjct: 1495 SQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTR 1554
Query: 1325 KSALATKVSRVQFDATTEQLNHMMQELVAK---MSGQEQDWQKMLDRLLTEMDNKLDRLE 1381
K+ +A K +QL +EL + + Q+ + + L ++ + ++ RLE
Sbjct: 1555 KAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLE 1614
Query: 1382 LDPVKQLLEDRWKSLRQQLRERPPLYQADE 1411
++L E + + L Q+ + P + E
Sbjct: 1615 ----RELREHQERHLEQRDEPQEPSNKVPE 1640
Score = 37.4 bits (85), Expect = 0.12
Identities = 108/545 (19%), Positives = 213/545 (39%), Gaps = 64/545 (11%)
Query: 996 DRVLSEGSEVSSEVLS---------ERRNSLRRMSSSFPTAVETFHLMGELSSLYVGLKE 1046
D +L+ G E +E+L E + L + T+ E HL + L LKE
Sbjct: 206 DELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNE--HLQKHVEDLLTKLKE 263
Query: 1047 SMKDLDEEQAGQTDLEKIQFLLAQMVKRTIPP------ELQEQLKTVKTLAKEVWQ-EKA 1099
+ + + + L+ + K EL ++ + L KE + KA
Sbjct: 264 AKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKA 323
Query: 1100 KVERLQRILEGEGNQEAGKELKAGELRLQLGVLRVTVADIEKELAELRESQDRGKAAMEN 1159
+ L + + + E K G L +L ++ +++ A L E + AAM
Sbjct: 324 IQDHLLEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEE---LAAMSP 380
Query: 1160 SVSEASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAHTLAPGQIDPEATCPACSLD 1219
+ + + ++ + KL + + + + LL + +K +I E A L
Sbjct: 381 TAAAVAKIVKPGM-KLTELYNAYVETQDQLL-LEKLENKRINKYLDEIVKEVEAKAPILK 438
Query: 1220 VSHQVSTLVRRYEQLQDMVNSLAVSRPSKKAKLQRQDEELLGRVQSAILQVQGDCEKLNI 1279
+ YE+ Q V SL+V ++QR +Q D +K N
Sbjct: 439 RQRE------EYERAQKAVASLSVKLEQAMKEIQR---------------LQEDTDKANK 477
Query: 1280 TTSNLIEDHRQKQKDIAMLYQGLEKL--EKEKANREHLEMEIDV-KADKSALATKVSR-V 1335
+S L D+R+ + + L Q + L E E+A H+ + +V AD S+ + +S+ +
Sbjct: 478 QSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHL 537
Query: 1336 QFDATTEQLNHMMQELVAKM----SGQEQDWQKMLDRLLTEMDNKLDR--LELDPVKQLL 1389
E+L Q L+ + +E++ Q+ +TE+ KL+ EL+ +++
Sbjct: 538 VSYRNIEELQQQNQRLLVALRELGETREREEQETTSSKITELQLKLESALTELEQLRKSR 597
Query: 1390 EDRWKSLRQQLRERPPLYQADEAAAMRRQLLAHFHCL---SCDRPLETPVTGHAIPVTPA 1446
+ + + + +R+R +Y+ + + H L S + P T +
Sbjct: 598 QHQMQLVDSIVRQR-DMYRILLSQTTGVAIPLHASSLDDVSLASTPKRPSTSQTVSTPAP 656
Query: 1447 GPGLPGHHSIRPYTVFELEQVRQHSRNLKLGSA----FPRGDLAQMEQSVGRLRSMHSKM 1502
P + +I L+Q+++ N K A L ++++ V LRS ++K+
Sbjct: 657 VPVIESTEAIEAKAA--LKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKI 714
Query: 1503 LMNIE 1507
++
Sbjct: 715 STQLD 719
>gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens]
Length = 971
Score = 53.9 bits (128), Expect = 1e-06
Identities = 91/453 (20%), Positives = 193/453 (42%), Gaps = 75/453 (16%)
Query: 998 VLSEGSEVSSEVLSERRNSLRRMSSSFPTAVETFHLMGELSSLYVGLKESMKDLDEEQAG 1057
+LS+ EV SE L+ R L++ +S ++ H+ G L + + + ++KDL+ E++
Sbjct: 234 LLSKHKEVESE-LAAARERLQQQASDL--VLKASHI-GMLQATQMTQEVTIKDLESEKSR 289
Query: 1058 QTD----LEKIQFLLAQMVKRTIPPELQEQLKTVKTL--AKEVWQE--KAKVERLQRILE 1109
+ LE+ + L + + Q+ L+ K + AK QE + +++ LQ LE
Sbjct: 290 VNERLSQLEEERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLE 349
Query: 1110 GEG---NQEAGKELKAGELRLQLGVLRV---TVADIEKELAELRESQDRGKAAMENSVSE 1163
E N+ K L+ + + + V + D +K +L E ++ K +E ++
Sbjct: 350 EEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQ 409
Query: 1164 ASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAHTLAPGQIDPEATCPACSLDVSHQ 1223
LQ +L+ L+ ++E L +++ ++ H
Sbjct: 410 ----LQQELENLKEVLEDKLNTANQ------------------------------EIGH- 434
Query: 1224 VSTLVRRYEQLQDMVNSLAVSRPSKKAKLQRQ---DEELLGRVQSAILQVQGDCEKLNIT 1280
+ +VR+ EQ L S + +LQ + ++ L + A+L V+G+
Sbjct: 435 LQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLNVEGE------- 487
Query: 1281 TSNLIEDHRQKQKDIAMLYQGLEKLEKEK-ANREHLEMEIDVKADKSALATKVSRVQFDA 1339
+E RQ+ ++ + EKL+ +K A+ ++ +++ + S L ++ +
Sbjct: 488 ----LEQERQQHEETIAAMKEEEKLKVDKMAHDLEIKWTENLRQECSKLREELRLQHEED 543
Query: 1340 TTEQLNHMMQELVAKMSGQEQDWQKMLDRLLTEMDNKLDRLELDPVK-----QLLEDRWK 1394
++ ++Q + + WQK ++ LL ++ LE+ + Q L+ ++
Sbjct: 544 KKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFT 603
Query: 1395 SLRQQLRERPPLYQADEAAAMRRQLLAHFHCLS 1427
RQ+L + L + +E R + L H L+
Sbjct: 604 QERQRLTQE--LEELEEQHQQRHKSLKEAHVLA 634
Score = 44.3 bits (103), Expect = 0.001
Identities = 83/384 (21%), Positives = 152/384 (39%), Gaps = 48/384 (12%)
Query: 1058 QTDLEKIQFLLAQMVKRTIPPELQEQLKTVKTLAKEVWQEKAKVERLQRILEGEGNQEAG 1117
Q EK + L + ++ E+QE LK+ + + V + + K E L R +E E +
Sbjct: 56 QVQFEKDKRLALEDLQAAHRREIQELLKSQQDHSASVNKGQEKAEELHR-MEVESLNKML 114
Query: 1118 KELKAGELRL---QLGVLRVTVADIEKELAELRESQ----------DRGKAAMENSVSEA 1164
+EL+ +L G L + E+EL L+ SQ +A +
Sbjct: 115 EELRLERKKLIEDYEGKLNKAQSFYERELDTLKRSQLFTAESLQASKEKEADLRKEFQGQ 174
Query: 1165 SLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAHTLAPG-------QIDPEATCPACS 1217
L+ + KL+ ++ + + +LL A +A Q+D
Sbjct: 175 EAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMAL 234
Query: 1218 LDVSHQV-STLVRRYEQLQDMVNSLAVSRPSKKAKLQRQD----------EELLGRVQSA 1266
L +V S L E+LQ + L V + S LQ E RV
Sbjct: 235 LSKHKEVESELAAARERLQQQASDL-VLKASHIGMLQATQMTQEVTIKDLESEKSRVNER 293
Query: 1267 ILQVQGDCEKLNITTSNLIEDHRQKQKDIAMLYQGLEKLEKEKANREHLEMEIDVKADKS 1326
+ Q++ + L T +L E+ +Q+ ++ ++ ++E RE ++ ++ + +
Sbjct: 294 LSQLEEERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVT 353
Query: 1327 ALATKVSRVQFDATTEQL---NHMMQELV-------AKMSGQEQDWQKMLDRLLTEMDNK 1376
L S+ T E+L +HM E V K + + Q D+L E D
Sbjct: 354 QLNEAHSK-----TLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKN 408
Query: 1377 LDRLELDPVKQLLEDRWKSLRQQL 1400
+ EL+ +K++LED+ + Q++
Sbjct: 409 QLQQELENLKEVLEDKLNTANQEI 432
>gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens]
Length = 1140
Score = 53.9 bits (128), Expect = 1e-06
Identities = 91/453 (20%), Positives = 193/453 (42%), Gaps = 75/453 (16%)
Query: 998 VLSEGSEVSSEVLSERRNSLRRMSSSFPTAVETFHLMGELSSLYVGLKESMKDLDEEQAG 1057
+LS+ EV SE L+ R L++ +S ++ H+ G L + + + ++KDL+ E++
Sbjct: 354 LLSKHKEVESE-LAAARERLQQQASDL--VLKASHI-GMLQATQMTQEVTIKDLESEKSR 409
Query: 1058 QTD----LEKIQFLLAQMVKRTIPPELQEQLKTVKTL--AKEVWQE--KAKVERLQRILE 1109
+ LE+ + L + + Q+ L+ K + AK QE + +++ LQ LE
Sbjct: 410 VNERLSQLEEERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLE 469
Query: 1110 GEG---NQEAGKELKAGELRLQLGVLRV---TVADIEKELAELRESQDRGKAAMENSVSE 1163
E N+ K L+ + + + V + D +K +L E ++ K +E ++
Sbjct: 470 EEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQ 529
Query: 1164 ASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAHTLAPGQIDPEATCPACSLDVSHQ 1223
LQ +L+ L+ ++E L +++ ++ H
Sbjct: 530 ----LQQELENLKEVLEDKLNTANQ------------------------------EIGH- 554
Query: 1224 VSTLVRRYEQLQDMVNSLAVSRPSKKAKLQRQ---DEELLGRVQSAILQVQGDCEKLNIT 1280
+ +VR+ EQ L S + +LQ + ++ L + A+L V+G+
Sbjct: 555 LQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLNVEGE------- 607
Query: 1281 TSNLIEDHRQKQKDIAMLYQGLEKLEKEK-ANREHLEMEIDVKADKSALATKVSRVQFDA 1339
+E RQ+ ++ + EKL+ +K A+ ++ +++ + S L ++ +
Sbjct: 608 ----LEQERQQHEETIAAMKEEEKLKVDKMAHDLEIKWTENLRQECSKLREELRLQHEED 663
Query: 1340 TTEQLNHMMQELVAKMSGQEQDWQKMLDRLLTEMDNKLDRLELDPVK-----QLLEDRWK 1394
++ ++Q + + WQK ++ LL ++ LE+ + Q L+ ++
Sbjct: 664 KKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFT 723
Query: 1395 SLRQQLRERPPLYQADEAAAMRRQLLAHFHCLS 1427
RQ+L + L + +E R + L H L+
Sbjct: 724 QERQRLTQE--LEELEEQHQQRHKSLKEAHVLA 754
Score = 44.3 bits (103), Expect = 0.001
Identities = 83/384 (21%), Positives = 152/384 (39%), Gaps = 48/384 (12%)
Query: 1058 QTDLEKIQFLLAQMVKRTIPPELQEQLKTVKTLAKEVWQEKAKVERLQRILEGEGNQEAG 1117
Q EK + L + ++ E+QE LK+ + + V + + K E L R +E E +
Sbjct: 176 QVQFEKDKRLALEDLQAAHRREIQELLKSQQDHSASVNKGQEKAEELHR-MEVESLNKML 234
Query: 1118 KELKAGELRL---QLGVLRVTVADIEKELAELRESQ----------DRGKAAMENSVSEA 1164
+EL+ +L G L + E+EL L+ SQ +A +
Sbjct: 235 EELRLERKKLIEDYEGKLNKAQSFYERELDTLKRSQLFTAESLQASKEKEADLRKEFQGQ 294
Query: 1165 SLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAHTLAPG-------QIDPEATCPACS 1217
L+ + KL+ ++ + + +LL A +A Q+D
Sbjct: 295 EAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMAL 354
Query: 1218 LDVSHQV-STLVRRYEQLQDMVNSLAVSRPSKKAKLQRQD----------EELLGRVQSA 1266
L +V S L E+LQ + L V + S LQ E RV
Sbjct: 355 LSKHKEVESELAAARERLQQQASDL-VLKASHIGMLQATQMTQEVTIKDLESEKSRVNER 413
Query: 1267 ILQVQGDCEKLNITTSNLIEDHRQKQKDIAMLYQGLEKLEKEKANREHLEMEIDVKADKS 1326
+ Q++ + L T +L E+ +Q+ ++ ++ ++E RE ++ ++ + +
Sbjct: 414 LSQLEEERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVT 473
Query: 1327 ALATKVSRVQFDATTEQL---NHMMQELV-------AKMSGQEQDWQKMLDRLLTEMDNK 1376
L S+ T E+L +HM E V K + + Q D+L E D
Sbjct: 474 QLNEAHSK-----TLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKN 528
Query: 1377 LDRLELDPVKQLLEDRWKSLRQQL 1400
+ EL+ +K++LED+ + Q++
Sbjct: 529 QLQQELENLKEVLEDKLNTANQEI 552
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 53.1 bits (126), Expect = 2e-06
Identities = 86/372 (23%), Positives = 154/372 (41%), Gaps = 61/372 (16%)
Query: 1044 LKESMKDLDEEQAGQT-DLEKIQFLLAQMVKR-----TIPPELQEQLKTVKTLAKEVWQE 1097
L+E +K D E + + +E Q L AQM K+ EL+E+L+ + V ++
Sbjct: 1125 LEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQ 1184
Query: 1098 KAK----VERLQRILEGEGNQEAGKELKAGELRLQLGVLRVTVADIEKELAELRESQDRG 1153
+A+ +E L LE G AG+ + +LG LR +EL E +
Sbjct: 1185 RAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLR-------RELEEAALRHEAT 1237
Query: 1154 KAAMENSVSEASLYLQDQLDKLRMIIESMLTSSSTL-LSMSMAPHKAHTLAPGQIDPEAT 1212
AA+ +E + L +Q+D L+ + + + S L + + TL + E
Sbjct: 1238 VAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKL 1297
Query: 1213 CPACSLDVSHQVSTLVRRYEQLQDMVNSLAVSRPSKKAKLQRQDEELLGRVQSAILQVQG 1272
C Q+S + E+LQ + + R GR+Q+ G
Sbjct: 1298 CRT----YEDQLSEAKIKVEELQRQLADASTQR---------------GRLQTE----SG 1334
Query: 1273 DCEKLNITTSNLIEDHRQKQKDIAMLYQGLEKLEKEKANREHLEMEIDVKADKSALATKV 1332
+ +L LI Q + A+ Q LE+L + ++E + KA KSALA V
Sbjct: 1335 ELSRLLEEKECLIS---QLSRGKALAAQSLEELRR--------QLEEESKA-KSALAHAV 1382
Query: 1333 SRVQFDATTEQLNHMMQELVAKMSGQEQDWQKMLDRLLTEMDNKLDRLELDPVKQL--LE 1390
++ D +++E + + + + Q++L + E+ + E D +++ LE
Sbjct: 1383 QALRHDC------DLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELE 1436
Query: 1391 DRWKSLRQQLRE 1402
+ K L +L+E
Sbjct: 1437 EAKKKLALRLQE 1448
Score = 41.2 bits (95), Expect = 0.008
Identities = 67/345 (19%), Positives = 143/345 (41%), Gaps = 38/345 (11%)
Query: 1085 KTVKTLAKEVWQEKAKVERLQRILEGEGNQEAGKELKAGELRLQLGVLRVTVADIEKELA 1144
K +T ++ + K KVE LQR L Q + ++GEL L EKE
Sbjct: 1296 KLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLE---------EKEC- 1345
Query: 1145 ELRESQDRGKAAMENSVSEASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAHTLAP 1204
L RGKA S+ E L+++ K + + + + + H+ A
Sbjct: 1346 -LISQLSRGKALAAQSLEELRRQLEEE-SKAKSALAHAVQALRHDCDLLREQHEEE--AE 1401
Query: 1205 GQIDPEATCPACSLDV----SHQVSTLVRRYEQLQDMVNSLAVSRPSKKAKLQRQDEELL 1260
Q + + + +V S + ++R E+L++ LA+ + ++ + +
Sbjct: 1402 AQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAK-C 1460
Query: 1261 GRVQSAILQVQGDCEKLNI-----TTSNLIEDHRQKQKDIAMLYQGLEKLEKEKANREHL 1315
++ A L++Q + E + + T++ D +Q+ + A LE+ + E +
Sbjct: 1461 SSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERA--------LEERRRQEEEM 1512
Query: 1316 EMEID-VKADKSALATKVSRVQFDATTEQLNHMMQELVAKMSGQEQDWQKMLDRLLTEMD 1374
+ E++ + + L T++ R++ E+ ++ L + +++ + D++ +
Sbjct: 1513 QRELEAAQRESRGLGTELFRLRHG--HEEALEALETLKRENKNLQEEISDLTDQV--SLS 1568
Query: 1375 NKLDRLELDPVKQLLEDRWKSLRQQLRERPPLYQADEAAAMRRQL 1419
K + EL+ K+ LE ++ L E + +E +R QL
Sbjct: 1569 GKSIQ-ELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQL 1612
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 52.0 bits (123), Expect = 5e-06
Identities = 95/423 (22%), Positives = 174/423 (41%), Gaps = 73/423 (17%)
Query: 1036 ELSSLYVGLKESMKDLDEE--------QAGQTDLE--KIQFLLAQMVKRTIPPELQEQLK 1085
++S+L GL+ +++ EE Q + DL K + L +M K + EL E+
Sbjct: 549 KMSALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQELLQLRMEKEEMEEELGEK-- 606
Query: 1086 TVKTLAKEVWQEKAKV--ERLQRILEGE--GNQEAGKELKAGELRLQLGVLRVTVADIEK 1141
++ L +E+ Q +A R +L+ E QE KEL+A E + Q R ++EK
Sbjct: 607 -IEVLQRELEQARASAGDTRQVEVLKKELLRTQEELKELQA-ERQSQEVAGRHRDRELEK 664
Query: 1142 ELAELRESQDRGKAAMENSVSEASLYLQDQLDKLRMIIES------MLTSSSTLLSMSMA 1195
+LA LR DRG+ + E +L LQ L +LR E + + +T+L A
Sbjct: 665 QLAVLRVEADRGR-----ELEEQNLQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRA 719
Query: 1196 PHKAHTLAPGQIDPEATCPACSLDVSHQVSTLVRRYEQLQDMVNSLAVSRPSKKAKLQR- 1254
+ TL Q + + + ++ L ++ ++ + +V+ + KLQR
Sbjct: 720 AVET-TLRETQEEND--------EFRRRILGLEQQLKETRGLVDGGEAVEARLRDKLQRL 770
Query: 1255 -----QDEELLG--------------RVQSAILQVQGDCEKLNITTSNLIEDHRQKQKDI 1295
Q EE L +++ + + Q +L L ++ K
Sbjct: 771 EAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTLNRALEEEGKQR 830
Query: 1296 AMLYQGLEKLEKEKANREHLEMEIDVKADKSALATKVSRVQFDATTEQLNHMMQELVAKM 1355
+L +G +LE++K + ++ + +K +K + Q A E + VA
Sbjct: 831 EVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQLEDYKEKARREVADA 890
Query: 1356 SGQEQDWQKMLDRL---LTEMDNKLDRL---------ELDPV---KQLLEDRWKSLRQQL 1400
Q +DW ++ L+ + +++ RL E D K+LL R + L Q+
Sbjct: 891 QRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQAERDTARLDKELLAQRLQGLEQEA 950
Query: 1401 RER 1403
+
Sbjct: 951 ENK 953
Score = 42.7 bits (99), Expect = 0.003
Identities = 96/441 (21%), Positives = 178/441 (40%), Gaps = 72/441 (16%)
Query: 1003 SEVSSEVLSERRNSLRRMSSSFPTAVETFHLMGELSSLYVGLKESMKD----LDEEQAGQ 1058
+E + VL +RR ++ T ET E +GL++ +K+ +D +A +
Sbjct: 707 AEAEATVLGQRRAAVET------TLRETQEENDEFRRRILGLEQQLKETRGLVDGGEAVE 760
Query: 1059 TDL-EKIQFLLAQM-------------------VKRTIPPELQEQLKTVKTLAKEVWQEK 1098
L +K+Q L A+ KR + L+E + + L +E
Sbjct: 761 ARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQ---- 816
Query: 1099 AKVERLQRILEGEGNQEAGKELKAGELRLQLGVLRVTVADIEKELAELRESQDRG----K 1154
+ L R LE EG Q EL Q +L TV + KEL ++ E + +
Sbjct: 817 ---QTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQLQ 873
Query: 1155 AAMENSVSEASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAHTLAPGQIDPEATCP 1214
A +E+ +A ++ D R + + T +S + L +A
Sbjct: 874 AQLEDYKEKAR---REVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQAERD 930
Query: 1215 ACSLDVSHQVSTLVRRYEQLQDMVNSLAVSRPSKKAKLQRQDEELLGRVQSAILQVQGDC 1274
LD L +R + L+ + S+ + +L+ +E++ + L+ + D
Sbjct: 931 TARLD----KELLAQRLQGLEQEAENKKRSQDDRARQLKGLEEKV------SRLETELDE 980
Query: 1275 EKLNITTSNLIEDHRQKQKDIAMLYQGLEKLEKEKANREHLE-----MEIDVKADKSALA 1329
EK T L+ D + +D + Q +L +E++ R+ LE +E K K+ LA
Sbjct: 981 EK---NTVELLTDRVNRGRD--QVDQLRTELMQERSARQDLECDKISLERQNKDLKTRLA 1035
Query: 1330 TKVSRVQFDATTEQLNHMMQELVAKMSGQE------QDWQKMLDRLLTEMDNKL--DRLE 1381
+ + A+ QL Q L ++ +E Q + L+R + E+ ++ +R
Sbjct: 1036 SSEGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQSTNRKLERKVKELSIQIEDERQH 1095
Query: 1382 LDPVKQLLEDRWKSLRQQLRE 1402
++ K L R K+L++Q+ E
Sbjct: 1096 VNDQKDQLSLRVKALKRQVDE 1116
Score = 38.9 bits (89), Expect = 0.042
Identities = 95/436 (21%), Positives = 181/436 (41%), Gaps = 65/436 (14%)
Query: 997 RVLSEGSEVSSEVLSERRNSLRRMSSSFPTAVETFHLMGELSSLYVGLKESMKD-LDEEQ 1055
R L +G E V + R+ L+R+ + E + E K +++ L+E Q
Sbjct: 750 RGLVDGGEA---VEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQ 806
Query: 1056 AGQTDLEKIQFLLAQMVKRTIPPELQEQLKTVKTLAKEVWQEKAKVERLQRILEGEGNQE 1115
G L + Q +T+ L+E+ K + L + KA++E +R+L+ ++
Sbjct: 807 RGLARLGQEQ--------QTLNRALEEEGKQREVLRRG----KAELEEQKRLLDRTVDR- 853
Query: 1116 AGKEL-KAGELRLQ-LGVLRVTVADI-EKELAELRESQDRGK--AAMENSVSEASLYLQD 1170
KEL K GE Q L L+ + D EK E+ ++Q + K A+ S LQD
Sbjct: 854 LNKELEKIGEDSKQALQQLQAQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQD 913
Query: 1171 QLDKLRMIIESMLTSSST------LLSMSMA--PHKAHTLAPGQIDPEATCPACSLDVS- 1221
++ +LR +++ T LL+ + +A Q D VS
Sbjct: 914 EIQRLRQALQASQAERDTARLDKELLAQRLQGLEQEAENKKRSQDDRARQLKGLEEKVSR 973
Query: 1222 ---------HQVSTLVRRYEQLQDMVNSLAVSRPSK----------KAKLQRQDEELLGR 1262
+ V L R + +D V+ L + K L+RQ+++L R
Sbjct: 974 LETELDEEKNTVELLTDRVNRGRDQVDQLRTELMQERSARQDLECDKISLERQNKDLKTR 1033
Query: 1263 VQSAILQVQGDCEKLNITTSNLIEDHRQKQKDIAMLYQGLEKLEKEKANREHLEMEIDVK 1322
+ S+ E +++L + Q Q +L + L+ E+EK + +++ K
Sbjct: 1034 LASS--------EGFQKPSASLSQLESQNQ----LLQERLQAEEREKTVLQSTNRKLERK 1081
Query: 1323 ADKSALATKVSRVQFDATTEQLNHMMQELVAKMSGQEQDWQKMLDRLLTEMDNKLDRLEL 1382
+ ++ + R + +QL+ ++ L ++ E++ ++ LD L + +++ E
Sbjct: 1082 VKELSIQIEDERQHVNDQKDQLSLRVKALKRQVDEAEEEIER-LDGLRKKAQREVE--EQ 1138
Query: 1383 DPVKQLLEDRWKSLRQ 1398
V + L+ R KSL +
Sbjct: 1139 HEVNEQLQARIKSLEK 1154
Score = 33.5 bits (75), Expect = 1.8
Identities = 45/217 (20%), Positives = 90/217 (41%), Gaps = 29/217 (13%)
Query: 1198 KAHTLAPGQIDPEATCPACSLDVSHQVSTLVRRYEQLQDMVNSLAVSRPSKKAKLQRQDE 1257
K L P Q+ E + + S L RR + Q L +L Q E
Sbjct: 381 KRQKLEPSQVGLERQLEEKTEECSRLQELLERRKGEAQQSNKEL-----QNMKRLLDQGE 435
Query: 1258 ELLGRVQSAILQVQGDCEKLN---ITTSNLIEDHRQKQKDIAMLYQGLEKLEKEKANREH 1314
+L +++ ++++Q + + L++D + ++ + + +G +++E++ RE
Sbjct: 436 DLRHGLETQVMELQNKLKHVQGPEPAKEVLLKDLLETRELLEEVLEGKQRVEEQLRLRER 495
Query: 1315 LEMEIDVKADKSALATKVS---------RVQFDATTEQLNHMMQELVAKMSGQEQDWQKM 1365
++ A K AL +V+ R Q+ TEQL MQ+ + E + QKM
Sbjct: 496 -----ELTALKGALKEEVASRDQEVEHVRQQYQRDTEQLRRSMQDATQDHAVLEAERQKM 550
Query: 1366 LDRLLTEMDNKLDRLELDPVKQLLEDRWKSLRQQLRE 1402
L+ + +L+ + W+S+ Q+ +E
Sbjct: 551 -SALVRGLQRELEETSEE------TGHWQSMFQKNKE 580
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 51.6 bits (122), Expect = 6e-06
Identities = 91/439 (20%), Positives = 179/439 (40%), Gaps = 63/439 (14%)
Query: 1004 EVSSEVLSERRNSLRRMSSSFPTAVETFHLMGELSS-LYVGLKESMKDLDEEQAGQTDLE 1062
E + EV + + L +S V + + + + L L + + DLD ++ +LE
Sbjct: 1381 ETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLE 1440
Query: 1063 KIQFLLAQMV--KRTIPPELQEQLKTVKTLAKEVWQEKAKVERLQRILEGEGNQEAGKEL 1120
K Q Q++ ++TI + E+ + A+E ++ K L R LE Q+A E
Sbjct: 1441 KKQKKFDQLLAEEKTISAKYAEERDRAEAEARE---KETKALSLARALEEAMEQKAELER 1497
Query: 1121 KAGELRLQLGVLRVTVADIEKELAELRESQDRGKAAMENSVSEASLYLQDQLDKLRMIIE 1180
+ R ++ L + D+ K + EL +S K A+E V E L++ D+L+ +
Sbjct: 1498 LNKQFRTEMEDLMSSKDDVGKSVHELEKS----KRALEQQVEEMKTQLEELEDELQATED 1553
Query: 1181 SMLTSSSTLLSM------------SMAPHKAHTLAPGQIDPEATCPACSLDVSHQVSTLV 1228
+ L L +M + K L + EA D Q S V
Sbjct: 1554 AKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELE----DERKQRSMAV 1609
Query: 1229 RRYEQLQDMVNSLAVSRPSKKAKLQRQDEEL--LGRVQSAILQVQGDCEKLNITTSNLIE 1286
++L+ + L S + +DE + L ++Q+ + + + + ++
Sbjct: 1610 AARKKLEMDLKDLEAHIDSAN---KNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILA 1666
Query: 1287 DHRQKQKDIAMLYQGLEKLEKEKA-----------NREHLEMEIDVKADKSALATKVSRV 1335
++ +K + + + +L++E A R+ L EI + K ALA + R
Sbjct: 1667 QAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKR- 1725
Query: 1336 QFDATTEQLNHMMQELVAKMSGQEQDWQKMLDRLLTEMDNKLDRLELD------------ 1383
+ +A QL ++E EQ ++++ L + + ++D++ D
Sbjct: 1726 RLEARIAQLEEELEE--------EQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNE 1777
Query: 1384 PVKQLLEDRWKSLRQQLRE 1402
+Q LE + K L+ +L+E
Sbjct: 1778 NARQQLERQNKELKVKLQE 1796
Score = 46.6 bits (109), Expect = 2e-04
Identities = 85/424 (20%), Positives = 174/424 (41%), Gaps = 62/424 (14%)
Query: 1032 HLMGELSSLYVGLKESMKDLDEEQAGQTDLEKIQFLLAQMVKR----------------- 1074
HL E + ++E + L+EE++ + L+ + +K+
Sbjct: 933 HLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAK 992
Query: 1075 ----------TIPPELQEQLKTVKTLAKEVWQEKAKV----ERLQRILEGEGNQEAGK-- 1118
L E+ + K+LAK + +A + ERL+R E + QE K
Sbjct: 993 EKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRR--EEKQRQELEKTR 1050
Query: 1119 ---ELKAGELRLQLGVLRVTVADIEKELAELRESQDRGKAAMENSVSEASLYLQDQLDKL 1175
E + +L Q+ L+ +A+++ +LA+ E A +E ++ ++ L+ +
Sbjct: 1051 RKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELE 1110
Query: 1176 RMIIESMLTSSSTLLSMSMAPHKAHTLAPGQIDPEATCPACSLD-VSHQVSTLVRRYEQL 1234
I E S S + A + L +++ T +LD + Q +R +++
Sbjct: 1111 SQISELQEDLESERASRNKAEKQKRDLGE-ELEALKTELEDTLDSTAAQQELRSKREQEV 1169
Query: 1235 QDMVNSLAVSRPSKKAKLQR------QDEELLGRVQSAILQVQGDCEKLNITTSNLIEDH 1288
+ +L + +A++Q Q E L +V+ + EK T N +
Sbjct: 1170 NILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLEN---ER 1226
Query: 1289 RQKQKDIAMLYQGLEKLEKEKANREHLEMEIDVKAD-----KSALATKVSRVQFDATTEQ 1343
+ ++ +L QG E ++ E E+ VK + ++ LA KV+++Q + +
Sbjct: 1227 GELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVE--LDN 1284
Query: 1344 LNHMMQELVAKMSGQEQDWQKMLDRL-----LTEMDNKLDRLELDPVKQLLEDRWKSLRQ 1398
+ ++ + +K S +D+ + +L L + +N+ +L L + +ED S R+
Sbjct: 1285 VTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENR-QKLSLSTKLKQVEDEKNSFRE 1343
Query: 1399 QLRE 1402
QL E
Sbjct: 1344 QLEE 1347
>gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens]
Length = 775
Score = 51.6 bits (122), Expect = 6e-06
Identities = 112/543 (20%), Positives = 217/543 (39%), Gaps = 54/543 (9%)
Query: 994 SVDRVLSEGSEVSSEVLSERRNSLRRMSSSFPTAVET-FHLMGELSSLYVGLKESMKDLD 1052
S+ V E S + + L++++ + + + A E L GEL L + E+ L
Sbjct: 171 SLATVTQEKSRMEASYLADKKKMKQDLEDASNKAEEERARLEGELKGLQEQIAETKARLI 230
Query: 1053 EEQAGQTDLEKIQFLLAQMVKRTIPPELQEQLKTVKTLAKEVWQEKAKVERLQRILEGEG 1112
+Q + + L+ + +++ + E + Q + ++ +E + A +EG
Sbjct: 231 TQQHDRAQEQSDHALMLRELQKLLQEE-RTQRQDLELRLEETREALAGRAYAAEQMEGFE 289
Query: 1113 NQEAGKELKAGELRLQLGVLRVTVADIEKELAELRESQDRGKAAME---------NSVSE 1163
Q + EL+ +L +R + L EL+E R K+ + +++E
Sbjct: 290 LQTKQLTREVEELKSELQAIRDEKNQPDPRLQELQEEAARLKSHFQAQLQQEMRKTALAE 349
Query: 1164 ASLYLQDQLDKLRMI-IESMLTSSSTLLSMSMAPHKAHTLAPGQIDPEATCPACSLDVSH 1222
L Q Q+++ R+ +E+ ++ S LL + LA ++ LD+ +
Sbjct: 350 DQLRQQSQVEEQRVAALENQISEVSELLGTYEKAKQKDQLAIQKLKERIL----QLDLEN 405
Query: 1223 QVSTLVRRYEQLQDM---VNSLAVSRPSKKAKLQRQDEELLGRVQSAILQVQGDCEKLNI 1279
+ L D +SL V+ K + ++ ++ R L V+ C+ L I
Sbjct: 406 KTLALAASSRSPLDSHGEESSLDVNVLKDKMEKLKRLLQVAARKSQVTLDVEKLCD-LEI 464
Query: 1280 TTSNLIEDHRQKQKDIAMLYQGLEKLEKEKANREHLEMEIDVKADKSALATKVSRV--QF 1337
S+ D +K A+ YQ K KE+ R + ++ +K+ TK + +
Sbjct: 465 MPSSEAADG---EKATALYYQQELKQLKEEFERYKMRAQVVLKSKN----TKDGNLGKEL 517
Query: 1338 DATTEQLNHMMQELVA-KMSGQE---------QDWQKMLDRLLTEMDNKLDRLELDPVKQ 1387
+A EQL + ++ ++ ++S +E DW++ L RL +L+R +LD
Sbjct: 518 EAAQEQLAELKEKYISLRLSCEELEHQHQQEADDWKQELARLQQLHRQELERCQLD---- 573
Query: 1388 LLEDRWKSLRQQLRERPPLYQADEAAAMRRQLLAHFHCLSCDRPLETPVTGHAIPVTPAG 1447
DR L ++L + Q D A A+ + L L + + G PV G
Sbjct: 574 -FRDRTLKLEEELHK-----QRDRALAVLTEKDLELEQLR-SVALASGLPGRRSPVGGGG 626
Query: 1448 PGLPGHHSIRPYTVFELEQVRQHSRNLKLGSAFPRGDLAQMEQSVGRLRSMHSKMLMNIE 1507
PG P S L+ + L + LA+ E + LR ++ + +
Sbjct: 627 PGDPADTSSSDSLTQALQLAAANEPTFFLYAE----QLARKEVEITSLRKQKHRLEVEVH 682
Query: 1508 KVQ 1510
++Q
Sbjct: 683 QLQ 685
Score = 32.0 bits (71), Expect = 5.1
Identities = 71/365 (19%), Positives = 138/365 (37%), Gaps = 45/365 (12%)
Query: 1079 ELQEQLKTVKTLAKEVWQEKAKVE--------RLQRILEGEGNQEAGKELKAGELRLQLG 1130
+L+ QL T+ + V QEK+++E ++++ LE N KA E R +L
Sbjct: 160 QLKTQLATLTSSLATVTQEKSRMEASYLADKKKMKQDLEDASN-------KAEEERARL- 211
Query: 1131 VLRVTVADIEKELAELRESQDRGKAAMENSVSEASLYLQDQLDKLRMIIESMLTSSSTLL 1190
E EL L+E KA + + + D LR + + + +
Sbjct: 212 ---------EGELKGLQEQIAETKARLITQQHDRAQEQSDHALMLRELQKLLQEERTQRQ 262
Query: 1191 SMSMAPHKAHTLAPGQIDPEATCPACSLDVSHQVSTLVRRYEQLQDMVNSLAVSRPSKKA 1250
+ + + G+ L Q L R E+L+ + ++ +
Sbjct: 263 DLELRLEETREALAGRAYAAEQMEGFEL----QTKQLTREVEELKSELQAIRDEKNQPDP 318
Query: 1251 KLQRQDEELLGRVQSAILQVQGDCEKLNITTSNLIEDHRQKQKDIAMLYQGLEKLEK--- 1307
+LQ EE Q+Q + K + L + + +++ +A L + ++ +
Sbjct: 319 RLQELQEEAARLKSHFQAQLQQEMRKTALAEDQLRQQSQVEEQRVAALENQISEVSELLG 378
Query: 1308 --EKANR---------EHLEMEIDVKADKSALATKVSRVQFDATTEQLNHMMQELVAKMS 1356
EKA + + +++D++ ALA SR D+ E+ + + L KM
Sbjct: 379 TYEKAKQKDQLAIQKLKERILQLDLENKTLALAAS-SRSPLDSHGEESSLDVNVLKDKME 437
Query: 1357 GQEQDWQKMLDRLLTEMD-NKLDRLELDPVKQLLEDRWKSLRQQLRERPPLYQADEAAAM 1415
++ Q + +D KL LE+ P + + + +E L + E M
Sbjct: 438 KLKRLLQVAARKSQVTLDVEKLCDLEIMPSSEAADGEKATALYYQQELKQLKEEFERYKM 497
Query: 1416 RRQLL 1420
R Q++
Sbjct: 498 RAQVV 502
>gi|33188443 microfilament and actin filament cross-linker protein
isoform b [Homo sapiens]
Length = 5938
Score = 51.2 bits (121), Expect = 8e-06
Identities = 71/287 (24%), Positives = 130/287 (45%), Gaps = 46/287 (16%)
Query: 986 VTLFRSPDSVDRVLSEGSEVSSEVLSERRNSLRRMSSSFPTAVETFHLMGELSSLYVGLK 1045
+ + R DS+D + S SE+ E++ L+ + S E L+ S Y L+
Sbjct: 4263 IDIIRHKDSMDELFSHRSEIFGTCGEEQKTVLQEKTESLIQQYEAISLLN--SERYARLE 4320
Query: 1046 ESMKDLDEEQAGQTDL----EKIQFLLAQMVKRTIPPE-LQEQLKTVKTLAKEVWQEKAK 1100
+ +++ +L E+ + L+AQ+ I E L++Q + ++ L + + + K
Sbjct: 4321 RAQVLVNQFWETYEELSPWIEETRALIAQLPSPAIDHEQLRQQQEEMRQLRESIAEHKPH 4380
Query: 1101 VERLQRILEGEGNQEAGKELKAGELRLQLG-VLRVTVADIEKELAELRESQDRGKAAMEN 1159
+++L +I G +LK EL + G ++ E A+++E + A++
Sbjct: 4381 IDKLLKI---------GPQLK--ELNPEEGEMVEEKYQKAENMYAQIKEEVRQRALALDE 4429
Query: 1160 SVSEASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAHTLAPGQIDPEATCPACSLD 1219
+VS+ S + + DK+ ++E++ SS L M P L P ++D C
Sbjct: 4430 AVSQ-STQITEFHDKIEPMLETLENLSSRL---RMPP-----LIPAEVDKIREC------ 4474
Query: 1220 VSHQVSTLVRRYEQLQDMVNSLAVSRPSKKAKLQRQDEELLGRVQSA 1266
+S S V E+LQ PS +A L+R+ EEL+GR Q A
Sbjct: 4475 ISDNKSATV-ELEKLQ----------PSFEA-LKRRGEELIGRSQGA 4509
Score = 47.0 bits (110), Expect = 2e-04
Identities = 92/446 (20%), Positives = 179/446 (40%), Gaps = 67/446 (15%)
Query: 1001 EGSEVSSEVLSERRNSLRRMSSSFPTAVETFHLMGELSSLYVGLKESMKDLDE-EQAGQT 1059
E SE+ + V + +++ R ++ + L Y + S L QA +
Sbjct: 2396 EPSEIGNLVKDKLKDATERYTALHSKCTRLGSHLNMLLGQYHQFQNSADSLQAWMQACEA 2455
Query: 1060 DLEKIQFLLAQMVKRTIPPELQEQLKTVKTLAKEVWQEKAKVERLQR----ILEGEGNQE 1115
++EK LL+ V P LQEQL T K L +E+ + + VE+LQ+ I+E EG
Sbjct: 2456 NVEK---LLSDTVASD-PGVLQEQLATTKQLQEELAEHQVPVEKLQKVARDIMEIEGEP- 2510
Query: 1116 AGKELKAGELRLQLGVLRVTVADIEKELAELRESQDRGKAAMENSVSEASLYLQDQLDKL 1175
A + + E +S ++ S++E S LQ + +
Sbjct: 2511 ---------------------APDHRHVQETTDSILSHFQSLSYSLAERSSLLQKAIAQS 2549
Query: 1176 RMIIESM--LTSSSTLLSMSMAPHKAHTLAPGQI-DPEATCPACSLDVSHQVSTL----- 1227
+ + ES+ L S + ++ + +L+ G I + AT D++ Q S+L
Sbjct: 2550 QSVQESLESLLQSIGEVEQNLEGKQVSSLSSGVIQEALATNMKLKQDIARQKSSLEATRE 2609
Query: 1228 -VRRYEQLQDMVNSLA-------VSRPSKKAKLQRQDEE-----LLGRVQSAILQVQGDC 1274
V R+ + D + VS+ ++ LQ+Q++E LL + + + G
Sbjct: 2610 MVTRFMETADSTTAAVLQGKLAEVSQRFEQLCLQQQEKESSLKKLLPQAE-MFEHLSGKL 2668
Query: 1275 EKLNITTSNLIEDHRQKQKDIAMLYQGLEKLEKE-KANREHLEMEIDVKADKSALATKVS 1333
++ S ++ Q +DI +Q +++L E + +E+L+ + + S+ +
Sbjct: 2669 QQFMENKSRMLASGNQPDQDITHFFQQIQELNLEMEDQQENLDTLEHLVTELSSCGFALD 2728
Query: 1334 RVQFDATTEQLNHMMQELVAKMSGQEQDWQKMLDRLLTEMDNKLDRLELDPVKQLLEDRW 1393
Q + L EL + +E+D + +LD ++L+
Sbjct: 2729 LCQHQDRVQNLRKDFTELQKTVKEREKDASSCQE-------------QLDEFRKLVRTFQ 2775
Query: 1394 KSLRQQLRERPPLYQADEAAAMRRQL 1419
K L++ PP + A + +Q+
Sbjct: 2776 KWLKETEGSIPPTETSMSAKELEKQI 2801
Score = 32.7 bits (73), Expect = 3.0
Identities = 75/343 (21%), Positives = 127/343 (37%), Gaps = 61/343 (17%)
Query: 1075 TIPP------ELQEQLKTVKTLAKEVWQEKAKVERLQRILEGEGNQEAGKELKAGELRLQ 1128
T+PP +++QL +K EV+Q++ ++E+L GEL L+
Sbjct: 4682 TMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNH---------------QGELMLK 4726
Query: 1129 LGVLRVTVADIEKELAELRESQDR--GKAAMENSVSEASLYLQDQLDKLRMIIESMLTSS 1186
I + L EL+ + K A E +L Q + S LT +
Sbjct: 4727 KATDETDRDIIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHT 4786
Query: 1187 STLLSMSMAPHKAHTLAPGQIDPE-ATCPACSLDV-SHQVSTLVRRYEQLQDMVNSLAVS 1244
LL + + P I+ E A DV +HQ + E + N L S
Sbjct: 4787 EELLD----AQRPISGDPKVIEVELAKHHVLKNDVLAHQATV-----ETVNKAGNELLES 4837
Query: 1245 RPSKKAKLQRQDEELLGRVQSAILQVQGDCEKLNITTSNLIEDHRQKQKDIAMLYQGLEK 1304
A R E + + ++LQ E+ Q+ + QG
Sbjct: 4838 SAGDDASSLRSRLEAMNQCWESVLQ--------------KTEEREQQLQSTLQQAQGFHS 4883
Query: 1305 LEKEKANREHLEMEIDVKADK-SALATKVSRVQFDATTEQLNHMMQELVAKMSGQEQDWQ 1363
E E E ME + A K + + +R Q D HM EL +++ +E+ +
Sbjct: 4884 -EIEDFLLELTRMESQLSASKPTGGLPETAREQLD------THM--ELYSQLKAKEETYN 4934
Query: 1364 KMLDR---LLTEMDNKLDRLELDPVKQLLEDRWKSLRQQLRER 1403
++LD+ +L D+ + + LLE +W + ++ ER
Sbjct: 4935 QLLDKGRLMLLSRDDSGSGSKTEQSVALLEQKWHVVSSKMEER 4977
>gi|33188445 microfilament and actin filament cross-linker protein
isoform a [Homo sapiens]
Length = 5430
Score = 51.2 bits (121), Expect = 8e-06
Identities = 71/287 (24%), Positives = 130/287 (45%), Gaps = 46/287 (16%)
Query: 986 VTLFRSPDSVDRVLSEGSEVSSEVLSERRNSLRRMSSSFPTAVETFHLMGELSSLYVGLK 1045
+ + R DS+D + S SE+ E++ L+ + S E L+ S Y L+
Sbjct: 3761 IDIIRHKDSMDELFSHRSEIFGTCGEEQKTVLQEKTESLIQQYEAISLLN--SERYARLE 3818
Query: 1046 ESMKDLDEEQAGQTDL----EKIQFLLAQMVKRTIPPE-LQEQLKTVKTLAKEVWQEKAK 1100
+ +++ +L E+ + L+AQ+ I E L++Q + ++ L + + + K
Sbjct: 3819 RAQVLVNQFWETYEELSPWIEETRALIAQLPSPAIDHEQLRQQQEEMRQLRESIAEHKPH 3878
Query: 1101 VERLQRILEGEGNQEAGKELKAGELRLQLG-VLRVTVADIEKELAELRESQDRGKAAMEN 1159
+++L +I G +LK EL + G ++ E A+++E + A++
Sbjct: 3879 IDKLLKI---------GPQLK--ELNPEEGEMVEEKYQKAENMYAQIKEEVRQRALALDE 3927
Query: 1160 SVSEASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAHTLAPGQIDPEATCPACSLD 1219
+VS+ S + + DK+ ++E++ SS L M P L P ++D C
Sbjct: 3928 AVSQ-STQITEFHDKIEPMLETLENLSSRL---RMPP-----LIPAEVDKIREC------ 3972
Query: 1220 VSHQVSTLVRRYEQLQDMVNSLAVSRPSKKAKLQRQDEELLGRVQSA 1266
+S S V E+LQ PS +A L+R+ EEL+GR Q A
Sbjct: 3973 ISDNKSATV-ELEKLQ----------PSFEA-LKRRGEELIGRSQGA 4007
Score = 47.0 bits (110), Expect = 2e-04
Identities = 92/446 (20%), Positives = 179/446 (40%), Gaps = 67/446 (15%)
Query: 1001 EGSEVSSEVLSERRNSLRRMSSSFPTAVETFHLMGELSSLYVGLKESMKDLDE-EQAGQT 1059
E SE+ + V + +++ R ++ + L Y + S L QA +
Sbjct: 1894 EPSEIGNLVKDKLKDATERYTALHSKCTRLGSHLNMLLGQYHQFQNSADSLQAWMQACEA 1953
Query: 1060 DLEKIQFLLAQMVKRTIPPELQEQLKTVKTLAKEVWQEKAKVERLQR----ILEGEGNQE 1115
++EK LL+ V P LQEQL T K L +E+ + + VE+LQ+ I+E EG
Sbjct: 1954 NVEK---LLSDTVASD-PGVLQEQLATTKQLQEELAEHQVPVEKLQKVARDIMEIEGEP- 2008
Query: 1116 AGKELKAGELRLQLGVLRVTVADIEKELAELRESQDRGKAAMENSVSEASLYLQDQLDKL 1175
A + + E +S ++ S++E S LQ + +
Sbjct: 2009 ---------------------APDHRHVQETTDSILSHFQSLSYSLAERSSLLQKAIAQS 2047
Query: 1176 RMIIESM--LTSSSTLLSMSMAPHKAHTLAPGQI-DPEATCPACSLDVSHQVSTL----- 1227
+ + ES+ L S + ++ + +L+ G I + AT D++ Q S+L
Sbjct: 2048 QSVQESLESLLQSIGEVEQNLEGKQVSSLSSGVIQEALATNMKLKQDIARQKSSLEATRE 2107
Query: 1228 -VRRYEQLQDMVNSLA-------VSRPSKKAKLQRQDEE-----LLGRVQSAILQVQGDC 1274
V R+ + D + VS+ ++ LQ+Q++E LL + + + G
Sbjct: 2108 MVTRFMETADSTTAAVLQGKLAEVSQRFEQLCLQQQEKESSLKKLLPQAE-MFEHLSGKL 2166
Query: 1275 EKLNITTSNLIEDHRQKQKDIAMLYQGLEKLEKE-KANREHLEMEIDVKADKSALATKVS 1333
++ S ++ Q +DI +Q +++L E + +E+L+ + + S+ +
Sbjct: 2167 QQFMENKSRMLASGNQPDQDITHFFQQIQELNLEMEDQQENLDTLEHLVTELSSCGFALD 2226
Query: 1334 RVQFDATTEQLNHMMQELVAKMSGQEQDWQKMLDRLLTEMDNKLDRLELDPVKQLLEDRW 1393
Q + L EL + +E+D + +LD ++L+
Sbjct: 2227 LCQHQDRVQNLRKDFTELQKTVKEREKDASSCQE-------------QLDEFRKLVRTFQ 2273
Query: 1394 KSLRQQLRERPPLYQADEAAAMRRQL 1419
K L++ PP + A + +Q+
Sbjct: 2274 KWLKETEGSIPPTETSMSAKELEKQI 2299
Score = 32.7 bits (73), Expect = 3.0
Identities = 75/343 (21%), Positives = 127/343 (37%), Gaps = 61/343 (17%)
Query: 1075 TIPP------ELQEQLKTVKTLAKEVWQEKAKVERLQRILEGEGNQEAGKELKAGELRLQ 1128
T+PP +++QL +K EV+Q++ ++E+L GEL L+
Sbjct: 4180 TMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNH---------------QGELMLK 4224
Query: 1129 LGVLRVTVADIEKELAELRESQDR--GKAAMENSVSEASLYLQDQLDKLRMIIESMLTSS 1186
I + L EL+ + K A E +L Q + S LT +
Sbjct: 4225 KATDETDRDIIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHT 4284
Query: 1187 STLLSMSMAPHKAHTLAPGQIDPE-ATCPACSLDV-SHQVSTLVRRYEQLQDMVNSLAVS 1244
LL + + P I+ E A DV +HQ + E + N L S
Sbjct: 4285 EELLD----AQRPISGDPKVIEVELAKHHVLKNDVLAHQATV-----ETVNKAGNELLES 4335
Query: 1245 RPSKKAKLQRQDEELLGRVQSAILQVQGDCEKLNITTSNLIEDHRQKQKDIAMLYQGLEK 1304
A R E + + ++LQ E+ Q+ + QG
Sbjct: 4336 SAGDDASSLRSRLEAMNQCWESVLQ--------------KTEEREQQLQSTLQQAQGFHS 4381
Query: 1305 LEKEKANREHLEMEIDVKADK-SALATKVSRVQFDATTEQLNHMMQELVAKMSGQEQDWQ 1363
E E E ME + A K + + +R Q D HM EL +++ +E+ +
Sbjct: 4382 -EIEDFLLELTRMESQLSASKPTGGLPETAREQLD------THM--ELYSQLKAKEETYN 4432
Query: 1364 KMLDR---LLTEMDNKLDRLELDPVKQLLEDRWKSLRQQLRER 1403
++LD+ +L D+ + + LLE +W + ++ ER
Sbjct: 4433 QLLDKGRLMLLSRDDSGSGSKTEQSVALLEQKWHVVSSKMEER 4475
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 50.8 bits (120), Expect = 1e-05
Identities = 93/449 (20%), Positives = 184/449 (40%), Gaps = 62/449 (13%)
Query: 984 QDVTLFRSPDSVDRVLSEGSEVSSEVLSERRNSLRRMSSSFPTAVETFHLMGELSSLYVG 1043
QD+T F++ L E ++ + + E N L+R +S + + L EL
Sbjct: 1554 QDITRFQNS------LKE-LQLQKQKVEEELNRLKRTASE--DSCKRKKLEEEL------ 1598
Query: 1044 LKESMKDLDEEQAGQTDLEKIQFLLAQMVKRTIPPELQEQLKTVKTLAKEVWQEKAKVER 1103
E M+ +EQA + Q A +VK+ +L++Q + +E + + ++ R
Sbjct: 1599 --EGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRR 1656
Query: 1104 LQRILEGEGNQEAGKELKAGELRLQLGVLRVTVADIEKELAELRESQDRGKAAMENSVSE 1163
L +E Q ++ + L+ + + D + L E + +R ++ EN E
Sbjct: 1657 LSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKE 1716
Query: 1164 ASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAHTLAPGQIDPEATCPACSLDVSHQ 1223
L L+++L LR+ + L G+ + ++ A L++ Q
Sbjct: 1717 -HLMLEEELRNLRLEYDD--------------------LRRGRSEADSDKNATILELRSQ 1755
Query: 1224 VSTLVRRYEQLQDMVNSLAVSRPSKK---AKLQRQDEELLGRVQSA---ILQVQGDCEKL 1277
+ R +LQ ++N L R + + K Q+Q E R+Q + QV + E L
Sbjct: 1756 LQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESL 1815
Query: 1278 NITTSNLIEDHRQKQKDIAMLYQGLEKLEKEKANREHLEME-IDVKADKSALATKVSRVQ 1336
+ L +D + Q+ L + LE E ++ LE E ++ D + T+ SR
Sbjct: 1816 LVKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSR-- 1873
Query: 1337 FDATTEQLNHMMQELVAKMSGQEQDWQKMLDRLLTEMDN---KLDRLELDPVKQLLEDRW 1393
+E + K+ + + ++ + L +E++ ++ R+E + ++ LED
Sbjct: 1874 -----------KEEAIRKIESEREKSEREKNSLRSEIERLQAEIKRIE-ERCRRKLEDST 1921
Query: 1394 KSLRQQLRERPPLYQADEAAAMRRQLLAH 1422
+ + QL YQ + +R +H
Sbjct: 1922 RETQSQLETERSRYQREIDKLRQRPYGSH 1950
Score = 37.7 bits (86), Expect = 0.094
Identities = 70/366 (19%), Positives = 141/366 (38%), Gaps = 49/366 (13%)
Query: 997 RVLSEGSEVSSEVLSERRNSLRRMSSSFPTAVETFHLMGELSSLYVGLKESMKDLDEEQA 1056
R E +SSEV + RR L+ S + H + L ES +++ Q+
Sbjct: 1649 RTQEELRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQS 1708
Query: 1057 GQTDLEKIQFLLAQMV--------------------KRTIPPELQEQLKT---------- 1086
+L K +L + + K EL+ QL+
Sbjct: 1709 LTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQG 1768
Query: 1087 -VKTLAKEVWQEKAKVERLQRILEGEGNQEAGKELKAGELRLQLGVLRVTVADIEKELAE 1145
+ L +E + ++E+ Q+ N+ + + ++ + L V + +E++ A
Sbjct: 1769 LINDLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKAR 1828
Query: 1146 LRESQDRGKAAMENSVSEASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAHTLAPG 1205
L+ +D A S EA ++ +L+ + I++ L T S +
Sbjct: 1829 LQRLEDELNRA--KSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESERE 1886
Query: 1206 QIDPEATCPACSLDVSHQVSTLVRRYEQ-----LQDMVNSLAVSRPSKKAKLQRQDEELL 1260
+ + E ++ ++ ++R E+ L+D +++++ QR+ ++L
Sbjct: 1887 KSEREKNSLRSEIE---RLQAEIKRIEERCRRKLEDSTRETQSQLETERSRYQREIDKLR 1943
Query: 1261 GRVQSAILQVQGDCEKLNITTSNLIEDHRQKQKDIAMLYQ-------GLEKLEKEKANRE 1313
R + + Q +CE + TS L+ D +K+ LY+ L+KL K K + E
Sbjct: 1944 QRPYGSHRETQTECE-WTVDTSKLVFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVE 2002
Query: 1314 HLEMEI 1319
+ EI
Sbjct: 2003 EVASEI 2008
>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 2 [Homo sapiens]
Length = 1403
Score = 50.8 bits (120), Expect = 1e-05
Identities = 45/184 (24%), Positives = 87/184 (47%), Gaps = 23/184 (12%)
Query: 1229 RRYEQLQDMVNSLAVSRPSKKAKLQRQDEELLGRVQSAILQVQGDCEKLNITTSNLIEDH 1288
R E+L+D + L V A++ G++++ I Q + E+ LIE++
Sbjct: 524 RLTEELKDQLKDLKVKYEGASAEV--------GKLRNQIKQNEMIVEEFKRDEGKLIEEN 575
Query: 1289 RQKQKDIAMLYQGLEKLEKEKANREHLEMEIDVKADKSALATKVSRVQFDATTEQLNHMM 1348
++ QK+++M ++E+EK R+ EME K + LA + +F+ L++ +
Sbjct: 576 KRLQKELSMC-----EMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEV 630
Query: 1349 QELVAKMSGQEQDWQKMLD---RLLTEMDNKLDRL-------ELDPVKQLLEDRWKSLRQ 1398
E K+ E++ +K L +L E++N +L E + VK LE + L +
Sbjct: 631 NEKAKKLVEMEREHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGK 690
Query: 1399 QLRE 1402
++ E
Sbjct: 691 KITE 694
Score = 35.8 bits (81), Expect = 0.36
Identities = 68/394 (17%), Positives = 167/394 (42%), Gaps = 55/394 (13%)
Query: 1045 KESMKDLDEEQAGQTDLEKIQFLLAQMVKRTIPPELQEQLKT-----VKTLAKEVWQEKA 1099
+E K L E + + +LE ++ LAQ VK PE EQ+K+ L K++ +
Sbjct: 642 REHEKSLSEIRQLKRELENVKAKLAQHVK----PEEHEQVKSRLEQKSGELGKKITELTL 697
Query: 1100 KVERLQRILEGEGNQEAGKELKAGELRLQLGVLRVTVADIEKELAELRESQDRGKA--AM 1157
K + LQ+ +E + +A L +++ + L+ S+D K+ A+
Sbjct: 698 KNQTLQKEIEKVYLDNKLLKEQAHNLTIEM----------KNHYVPLKVSEDMKKSHDAI 747
Query: 1158 ENSVSEASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAHTLAPGQIDPEATCPACS 1217
+ ++ L + + + ++ +E +L + + LS ++ + + P + + E +
Sbjct: 748 IDDLNRKLLDVTQKYTEKKLEMEKLLLENDS-LSKDVSRLETVFVPPEKHEKEIIALKSN 806
Query: 1218 L-DVSHQVSTLVRRYEQLQDMVNSLAVSRPSKKAKLQRQDEELLGRVQSAILQVQGDCEK 1276
+ ++ Q+S L ++ + Q+ +++L + K + Q + E+
Sbjct: 807 IVELKKQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYVPVKTH------------EE 854
Query: 1277 LNITTSNLIEDHRQKQKDIAMLYQGL-EKLEKEKANREHLEMEIDVKADKSALATKVSRV 1335
+ +T ++ + ++ D+ ++ + ++ K K E L+ ++ A +S
Sbjct: 855 VKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLE-NTQNQIKAEYISLA 913
Query: 1336 QFDATTEQLNHMMQELVAKMSGQEQDWQKMLDRLLT-EMDNKLDRLELDPVKQLLEDRW- 1393
+ +A L+ M+++ + +++K + ++T + K + ELD +++ ++ ++
Sbjct: 914 EHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYA 973
Query: 1394 ----------------KSLRQQLRERPPLYQADE 1411
K L+ QL E+ Y E
Sbjct: 974 PIVSFEECERKFKATEKELKDQLSEQTQKYSVSE 1007
>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 1 [Homo sapiens]
Length = 1416
Score = 50.8 bits (120), Expect = 1e-05
Identities = 45/184 (24%), Positives = 87/184 (47%), Gaps = 23/184 (12%)
Query: 1229 RRYEQLQDMVNSLAVSRPSKKAKLQRQDEELLGRVQSAILQVQGDCEKLNITTSNLIEDH 1288
R E+L+D + L V A++ G++++ I Q + E+ LIE++
Sbjct: 537 RLTEELKDQLKDLKVKYEGASAEV--------GKLRNQIKQNEMIVEEFKRDEGKLIEEN 588
Query: 1289 RQKQKDIAMLYQGLEKLEKEKANREHLEMEIDVKADKSALATKVSRVQFDATTEQLNHMM 1348
++ QK+++M ++E+EK R+ EME K + LA + +F+ L++ +
Sbjct: 589 KRLQKELSMC-----EMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEV 643
Query: 1349 QELVAKMSGQEQDWQKMLD---RLLTEMDNKLDRL-------ELDPVKQLLEDRWKSLRQ 1398
E K+ E++ +K L +L E++N +L E + VK LE + L +
Sbjct: 644 NEKAKKLVEMEREHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGK 703
Query: 1399 QLRE 1402
++ E
Sbjct: 704 KITE 707
Score = 35.8 bits (81), Expect = 0.36
Identities = 68/394 (17%), Positives = 167/394 (42%), Gaps = 55/394 (13%)
Query: 1045 KESMKDLDEEQAGQTDLEKIQFLLAQMVKRTIPPELQEQLKT-----VKTLAKEVWQEKA 1099
+E K L E + + +LE ++ LAQ VK PE EQ+K+ L K++ +
Sbjct: 655 REHEKSLSEIRQLKRELENVKAKLAQHVK----PEEHEQVKSRLEQKSGELGKKITELTL 710
Query: 1100 KVERLQRILEGEGNQEAGKELKAGELRLQLGVLRVTVADIEKELAELRESQDRGKA--AM 1157
K + LQ+ +E + +A L +++ + L+ S+D K+ A+
Sbjct: 711 KNQTLQKEIEKVYLDNKLLKEQAHNLTIEM----------KNHYVPLKVSEDMKKSHDAI 760
Query: 1158 ENSVSEASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAHTLAPGQIDPEATCPACS 1217
+ ++ L + + + ++ +E +L + + LS ++ + + P + + E +
Sbjct: 761 IDDLNRKLLDVTQKYTEKKLEMEKLLLENDS-LSKDVSRLETVFVPPEKHEKEIIALKSN 819
Query: 1218 L-DVSHQVSTLVRRYEQLQDMVNSLAVSRPSKKAKLQRQDEELLGRVQSAILQVQGDCEK 1276
+ ++ Q+S L ++ + Q+ +++L + K + Q + E+
Sbjct: 820 IVELKKQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYVPVKTH------------EE 867
Query: 1277 LNITTSNLIEDHRQKQKDIAMLYQGL-EKLEKEKANREHLEMEIDVKADKSALATKVSRV 1335
+ +T ++ + ++ D+ ++ + ++ K K E L+ ++ A +S
Sbjct: 868 VKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLE-NTQNQIKAEYISLA 926
Query: 1336 QFDATTEQLNHMMQELVAKMSGQEQDWQKMLDRLLT-EMDNKLDRLELDPVKQLLEDRW- 1393
+ +A L+ M+++ + +++K + ++T + K + ELD +++ ++ ++
Sbjct: 927 EHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYA 986
Query: 1394 ----------------KSLRQQLRERPPLYQADE 1411
K L+ QL E+ Y E
Sbjct: 987 PIVSFEECERKFKATEKELKDQLSEQTQKYSVSE 1020
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 50.8 bits (120), Expect = 1e-05
Identities = 71/385 (18%), Positives = 162/385 (42%), Gaps = 27/385 (7%)
Query: 1053 EEQAGQTDLEKI-----QFLLAQMVKRTIPPELQEQLKTVKTLAKEVWQEKAKVERLQRI 1107
E QA T+L K+ + ++ Q R LQE++ + +E + ++E+++++
Sbjct: 1485 EVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKL 1544
Query: 1108 LEGEGNQ------EAGKELKAGE---LRLQLGVLRVTVADIEKELAELRESQDRGKAAME 1158
+E E + E L+ E L QL +L A++E++L+E E + + +
Sbjct: 1545 IEEEKTEVQVTLEETEGALERNESKILHFQLELLEAK-AELERKLSEKDEEIENFRRKQQ 1603
Query: 1159 NSVSEASLYLQDQ------LDKLRMIIESMLTSSSTLLSMSMAPHKAHTLAPGQIDPEAT 1212
++ L + + +L+ +E L LS + T + GQ+ +
Sbjct: 1604 CTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIK 1663
Query: 1213 CPACSLDVSHQVSTLVRRYEQLQDMVNSLAVSRPSKKAKLQRQDEELLGRVQSAILQVQG 1272
LD S Q+++ ++ + + NSL S LQ Q E + +L+
Sbjct: 1664 DLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATE 1723
Query: 1273 DCEKLNITTSNLIEDHRQKQKDIAMLYQGLEKLEKEKANREHLEMEIDVKADKSALATKV 1332
++L+ ++ + D+A + + E++ +E N E + ++A + K
Sbjct: 1724 RINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKK 1783
Query: 1333 SR---VQFDATTEQLNHMMQELVAKMSGQEQDWQKMLDRLLTEMDNKLDRLELD---PVK 1386
+ + T E + + +L +++ EQ + + ++++++ LE + ++
Sbjct: 1784 KQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIR 1843
Query: 1387 QLLEDRWKSLRQQLRERPPLYQADE 1411
+ E + + R + + YQA+E
Sbjct: 1844 RSAEAQRGARRLERCIKELTYQAEE 1868
Score = 31.6 bits (70), Expect = 6.7
Identities = 60/300 (20%), Positives = 113/300 (37%), Gaps = 34/300 (11%)
Query: 1136 VADIEKELAELRESQDRGKAAMENSVSEASLYLQDQLDKLRMIIESMLTSSSTLLSMSMA 1195
VA +++E A+L+++ ++ + E ++ Q++ D +I + TL ++
Sbjct: 861 VAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKND----LILQLQAEQETLANVE-- 914
Query: 1196 PHKAHTLAPGQIDPEATCPACSLDVSHQV---STLVRRYEQLQDMVNSLAVSRPS----- 1247
+ L +I EA S V + S L R +L+D L
Sbjct: 915 -EQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETML 973
Query: 1248 -KKAKLQRQDEELLGRVQSAILQVQGDCEKLNITTSNLIEDHRQKQKDIAMLYQGLEKLE 1306
K K +R E + + + + D KLN + E H+Q D+ M + L L
Sbjct: 974 VKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLS 1033
Query: 1307 KEKANREHLEMEIDVKADKSALA--------------TKVSRVQFDATTEQLNHMMQELV 1352
K E E++ ++ A K++R + H+ +EL
Sbjct: 1034 KANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELR 1093
Query: 1353 AKMSGQEQDWQKMLDR--LLTEMDNKLDRL--ELDPVKQLLEDRWKSLRQQLRERPPLYQ 1408
K Q K+ + L+ ++ + L ++ +K+ LE + + RER L Q
Sbjct: 1094 KKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQ 1153
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 50.8 bits (120), Expect = 1e-05
Identities = 97/481 (20%), Positives = 205/481 (42%), Gaps = 75/481 (15%)
Query: 942 SMYPGYRGPGYLSADQHG-QEGLDPNRTRASDRHGIPAQKAPGQDVTLFRSPDSVDRVLS 1000
S PG P + + +QH Q L+ N P + +D + + SV ++ +
Sbjct: 1258 SSTPGLEEPLFKATEQHHTQPVLESNLC--------PDWPSHSEDASALQGGTSVAQIKA 1309
Query: 1001 EGSEVSSEVLSERRNSLRRMSSSFPTAVETFHLMGELSSLYVGLKESMKDLDEE-----Q 1055
+ E+ +E + S + E F L +++ + + ES+K + E +
Sbjct: 1310 QLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEI-ESLKTVSHEAEVHAE 1368
Query: 1056 AGQTDLEKIQFLLAQMVK-RTIPPELQEQLKTVKT-------LAKEVWQEKAKVERLQ-R 1106
+ Q LE Q +A + R + P+L E K + L+ ++ +++A + ++Q
Sbjct: 1369 SLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTE 1428
Query: 1107 ILEGEGNQEA---GKELKAGELRLQLGVLRVTVADIEKELAELRESQDRGKAAMENSVSE 1163
I+E E +A E++A E ++ L+V + +++++ E+ E + R K ++ +
Sbjct: 1429 IIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGE-ESRAKQQIQRKLQA 1487
Query: 1164 ASLYLQDQLDKLRMIIESMLTSSSTL--LSMSMAPHKAHTLAPGQIDPEATCPACSLDVS 1221
A + ++ L + + + E + + T+ L+ S+A DV
Sbjct: 1488 ALISRKEALKENKSLQEELSLARGTIERLTKSLA-----------------------DVE 1524
Query: 1222 HQVSTLVRRYEQLQDMVNSLAVSRPSKKAKLQR---QDEELLGRVQSAILQVQG---DCE 1275
QVS + + + + L R ++ R +++ L +S L ++G D E
Sbjct: 1525 SQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKE 1584
Query: 1276 KL-----NITTSNLIED------HRQKQKDIAMLYQGLEKLEKEKANREHLEMEIDVKAD 1324
KL ++ +S + E H++ QK+ +L Q E + E +H+ V+ +
Sbjct: 1585 KLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEA--VRQE 1642
Query: 1325 KSALATKVSRVQFD--ATTEQLNHMMQELVAKMSGQEQDWQKMLDRLLTEMDNKLDRLEL 1382
K L K+ + + T +QL QE+ +M + + + K + + E++ + DRL
Sbjct: 1643 KQELYGKLRSTEANKKETEKQLQEAEQEM-EEMKEKMRKFAKSKQQKILELEEENDRLRA 1701
Query: 1383 D 1383
+
Sbjct: 1702 E 1702
Score = 47.4 bits (111), Expect = 1e-04
Identities = 88/405 (21%), Positives = 178/405 (43%), Gaps = 54/405 (13%)
Query: 996 DRVLSEGSEVSSEVLSERRNSLRRMSSSFPTAV---------ETFH---LMGELSSLYVG 1043
D++LS+ E+S +++E R ++++ + A +T H L ++ SL +
Sbjct: 747 DQLLSQVKELS--MVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIE 804
Query: 1044 LKESMKDLDEEQAGQTDLEKIQFLLAQMVKRTIPPELQEQLKTVKTLAKEVWQEKAKVER 1103
K ++ Q D++ +QF + R++ +LQ + V A+ V +KVE
Sbjct: 805 AKSKDVKIEVLQNELDDVQ-LQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEE 863
Query: 1104 LQRILEGEGNQEAGKELKAGELRLQLGVLRVTVADIEKELAELRESQDRGKAAMENSVSE 1163
L + L + KEL E+ +L D+E L + E +D+ + S++E
Sbjct: 864 LSQAL-------SQKEL---EITKMDQLLLEKKRDVET-LQQTIEEKDQQVTEISFSMTE 912
Query: 1164 ASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAHTLAPGQIDPEATCPACSLDVSHQ 1223
+ L ++ L + I++ L LLS + K ++ + + Q
Sbjct: 913 KMVQLNEEKFSLGVEIKT-LKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQ 971
Query: 1224 VSTLVRRYEQLQDMVNSLAVSRPSKKAKLQR---QDEELLGRVQSAILQVQGDCEKLNIT 1280
+S E+LQ + L +K KLQ +ELL RV +L
Sbjct: 972 ISK-----EELQHEFDLLKKENEQRKRKLQAALINRKELLQRVS-----------RLEEE 1015
Query: 1281 TSNLIEDHRQKQKDIAMLYQGLEKLEKEKANREHLEMEIDVKADKSALATKVSRVQFDAT 1340
+NL +D +K+ ++ +G ++E++K N+E+ E + K + + K + + +
Sbjct: 1016 LANL-KDESKKEIPLSETERG--EVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEV- 1071
Query: 1341 TEQLNHMMQELVAKMSGQE--QDWQKMLDRLLTEMDNKLDRLELD 1383
+L H+ ++L K++ +E Q K +++ L + N++D L+ +
Sbjct: 1072 --ELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAE 1114
Score = 47.4 bits (111), Expect = 1e-04
Identities = 75/379 (19%), Positives = 154/379 (40%), Gaps = 43/379 (11%)
Query: 1044 LKESMKDLDEEQA-GQTDLEKIQFLLAQMVKRTIPPELQEQLKTVKTLAKEVWQEKAKV- 1101
L+ ++K L+ Q Q DLE + LAQ V+ + Q +L + K L + E A+V
Sbjct: 2038 LERTVKALEFVQTESQKDLEITKENLAQAVEHR--KKAQAELASFKVLLDDTQSEAARVL 2095
Query: 1102 -ERLQRILEGEGNQEAGK---ELKAGELRLQLGVLRVTVADIEKELAELRESQDRGKAAM 1157
+ L+ E + N+E+ K + K +L +L +K + E ++ R K +
Sbjct: 2096 ADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHL 2155
Query: 1158 ENSVSEASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAHTLAPGQIDPEATCPACS 1217
E ++ E + L + +++ + E++ ++ + L + + + ID
Sbjct: 2156 EETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKF 2215
Query: 1218 LDVSHQVSTLVRRYEQ----LQDMVNSLAVSRPSKKAKLQRQDEELL---GRVQSAILQV 1270
D +R E L+D + +++ K + R + + + Q+ +
Sbjct: 2216 SDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQ 2275
Query: 1271 QGDCEKLNITTSNLIED-------HRQKQKDIAMLYQ--------------GLEKLEKEK 1309
Q C+ L L+ + Q ++A L LEK +++K
Sbjct: 2276 QKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQK 2335
Query: 1310 ANREHL--EMEIDVKADKSALA-----TKVSRVQFDATTEQLNHMMQELVAKMSGQEQDW 1362
N E + + E D++ K + + SR E++N Q++++ +SG+E+
Sbjct: 2336 GNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAI 2395
Query: 1363 QKMLDRLLTEMDNKLDRLE 1381
Q + L + D ++ LE
Sbjct: 2396 QVAIAELRQQHDKEIKELE 2414
Score = 40.8 bits (94), Expect = 0.011
Identities = 87/454 (19%), Positives = 177/454 (38%), Gaps = 37/454 (8%)
Query: 968 TRASDRHGIPAQKAPGQDVTL-FRSPDSVDRVLSEGSEVSSEV--LSERRNSLRRMSSSF 1024
TR + +P+ K+ V+ F S D ++ L + ++ + L E + + S +
Sbjct: 1807 TRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTL 1866
Query: 1025 PTAVETFHLMGELSSLYVGLKESMKDLDE----EQAGQTDLEKIQFL--LAQMVKRTIPP 1078
T L+ ++S+ LK +++ + Q Q +L ++ L A+ K +
Sbjct: 1867 ENEKNT--LLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEE 1924
Query: 1079 ELQEQLKTVKTLAKEVWQEKAKVERLQRILEGEGNQEAGKELKAGELRLQLGVLRVTV-A 1137
L QL + Q+ + +LE E + E + QL + V +
Sbjct: 1925 RLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVES 1984
Query: 1138 DIEKELAELRESQDRGKAAMENSVSEASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPH 1197
+I KE E + + + ++ E L+++ +++ + + + + ++
Sbjct: 1985 EIRKEYLEKIQGAQK-EPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2043
Query: 1198 KAHTL-APGQIDPEATCPACSLDVSHQ--VSTLVRRYEQLQDMVNSLAVSRPSKKAKLQR 1254
+ Q D E T + V H+ + ++ L D S A + KL++
Sbjct: 2044 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKK 2103
Query: 1255 QDEELLGRVQSAILQVQGDCEKLNITTSNLIEDHRQKQKDIAMLYQGLEKLEKEKANREH 1314
+ + V+S + Q D E+ E H +++K+ + + L+ L +EK + E
Sbjct: 2104 ELQSNKESVKSQMKQKDEDLER---RLEQAEEKHLKEKKN---MQEKLDALRREKVHLEE 2157
Query: 1315 LEMEIDVKADKSALATKVSRVQFDATTEQLNHMMQELVAKMSGQEQDWQKMLDRLLTEMD 1374
EI V +K + + D+T QL MS + D +++D
Sbjct: 2158 TIGEIQVTLNKKDKEVQQLQENLDSTVTQL----AAFTKSMSSLQDDRDRVIDEA----- 2208
Query: 1375 NKLDRLELDPVK------QLLEDRWKSLRQQLRE 1402
K +R D ++ +L ED L+ QLR+
Sbjct: 2209 KKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQ 2242
Score = 32.3 bits (72), Expect = 3.9
Identities = 76/433 (17%), Positives = 178/433 (41%), Gaps = 75/433 (17%)
Query: 1045 KESMKDLDEEQ----AGQTDLEKIQFLLAQMVKRTIPPELQEQLKTVKTLAKEVWQEKAK 1100
KE + L+E + + Q +L K++ L L++QL + ++ ++K
Sbjct: 2287 KELLSQLEETRHLYHSSQNELAKLESELKS---------LKDQLTDLSNSLEKCKEQKGN 2337
Query: 1101 VERLQRILEG------------EGNQEAGKELKAG---ELRLQ----LGVLRVTVADIEK 1141
+E + R E E + +A +EL + E+ ++ + +L I+
Sbjct: 2338 LEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQV 2397
Query: 1142 ELAELRESQDRGKAAMENSVS---EASLYLQDQ----LDKLRMIIESMLT---------- 1184
+AELR+ D+ +EN +S E ++ L+++ +DK ++E++ T
Sbjct: 2398 AIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKA 2457
Query: 1185 -SSSTLLSMSMAPHKAHTLAPGQIDPEATCPACSLDVSHQVSTLVRRYEQLQDMVNSLAV 1243
S + SMS + + E + L+ + +L++ + L
Sbjct: 2458 QLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRS 2517
Query: 1244 SRPSKKAKLQRQDEELLGRVQ--SAILQVQGDCEKLNITTSNLIEDHRQKQKDIAMLYQG 1301
++ + D EL+ + + ++ ++ +K L+E Q+ K++ Y
Sbjct: 2518 HMDDLNSENAKLDAELIQYREDLNQVITIKDSQQK------QLLEVQLQQNKELENKYAK 2571
Query: 1302 LEK--LEKEKANREHLEMEIDVKADKSALATKVS--RVQFDATTEQLNHMMQE-----LV 1352
LE+ E E+AN + ++ +K L+ ++ +V T Q+ + +E
Sbjct: 2572 LEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYH 2631
Query: 1353 AKMSGQEQDWQKM------LDRLLTEMDNKLDRLELDPVKQL--LEDRWKSLRQQLRERP 1404
A++ +E++ ++ + + E++ +L ++ + K++ +ED+ K + L
Sbjct: 2632 AQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDA 2691
Query: 1405 PLYQADEAAAMRR 1417
+ + + A R
Sbjct: 2692 GIMRNETETAEER 2704
>gi|55749708 outer dense fiber of sperm tails 2-like isoform b [Homo
sapiens]
Length = 513
Score = 50.8 bits (120), Expect = 1e-05
Identities = 91/392 (23%), Positives = 170/392 (43%), Gaps = 52/392 (13%)
Query: 1005 VSSEVLSERRNSLRRMSSSFPTAVETFHLMGELSSLYVGLKESMKDLDE----EQAGQTD 1060
V E ++ +L++ S + ++ H G + L +++ L E A ++
Sbjct: 99 VMKEASRQKTVALKKASKVYKQRLD--HFTGAIEKLTSQIRDQEAKLSETISASNAWKSH 156
Query: 1061 LEKIQFLLAQMVKRTIPPELQEQLKTVKTLAKEVWQEKAKVE-----RLQRILEGEGNQE 1115
EKI ++++T EL+ Q++T+K + ++ K+E + IL + E
Sbjct: 157 YEKI------VIEKT---ELEVQIETMKKQIINLLEDLKKMEDHGKNSCEEILRKVHSIE 207
Query: 1116 AGKE---LKAGELRLQLGVLRVTVADIEKELAELRESQDRGKAAMENSVSEASLYLQDQL 1172
E L+ +L+ L L+ V +E EL+EL+E + + K +E ++ LQ+
Sbjct: 208 YENETLNLENTKLKTTLAALKDEVVSVENELSELQEVEKKQKTLIEMYKTQVQK-LQEAA 266
Query: 1173 DKLRMIIESMLTSSSTLLSMSMAPHKAHTLAPGQIDPEATCPACSLDVSHQVSTLVRRYE 1232
+ ++ E++L ++ + + +K GQ++ ++ +L
Sbjct: 267 EIVKSRCENLLHKNNQI---TKTKNKNVEKMRGQMESHLK------ELERVCDSLTAAER 317
Query: 1233 QLQDMVNSLAVSRPSKKAKLQRQDEELLGRVQSAILQVQGDCEKLNITTSNLIEDHRQKQ 1292
+L + SL + K A + EL G QV G+ L T +L E++ Q
Sbjct: 318 RLHECQESLQCCK-GKCADQEHTIRELQG-------QVDGNHNLL--TKLSLEEENCLIQ 367
Query: 1293 KDIAMLYQGLEK-------LEKEKANREHLEMEIDVK-ADKSALATKVSRVQFDATTEQL 1344
L Q LE+ LEK+ AN+E ++K +KSA T ++R Q +A E+
Sbjct: 368 LKCENLQQKLEQMDAENKELEKKLANQEECLKHSNLKFKEKSAEYTALAR-QLEAALEEG 426
Query: 1345 NHMMQELVAKMSGQEQDWQKMLDRLLTEMDNK 1376
+ E + KMS +E Q + L TE+ K
Sbjct: 427 RQKVAEEIEKMSSRESALQIKILDLETELRKK 458
>gi|55749696 outer dense fiber of sperm tails 2-like isoform a [Homo
sapiens]
Length = 644
Score = 50.8 bits (120), Expect = 1e-05
Identities = 91/392 (23%), Positives = 170/392 (43%), Gaps = 52/392 (13%)
Query: 1005 VSSEVLSERRNSLRRMSSSFPTAVETFHLMGELSSLYVGLKESMKDLDE----EQAGQTD 1060
V E ++ +L++ S + ++ H G + L +++ L E A ++
Sbjct: 230 VMKEASRQKTVALKKASKVYKQRLD--HFTGAIEKLTSQIRDQEAKLSETISASNAWKSH 287
Query: 1061 LEKIQFLLAQMVKRTIPPELQEQLKTVKTLAKEVWQEKAKVE-----RLQRILEGEGNQE 1115
EKI ++++T EL+ Q++T+K + ++ K+E + IL + E
Sbjct: 288 YEKI------VIEKT---ELEVQIETMKKQIINLLEDLKKMEDHGKNSCEEILRKVHSIE 338
Query: 1116 AGKE---LKAGELRLQLGVLRVTVADIEKELAELRESQDRGKAAMENSVSEASLYLQDQL 1172
E L+ +L+ L L+ V +E EL+EL+E + + K +E ++ LQ+
Sbjct: 339 YENETLNLENTKLKTTLAALKDEVVSVENELSELQEVEKKQKTLIEMYKTQVQK-LQEAA 397
Query: 1173 DKLRMIIESMLTSSSTLLSMSMAPHKAHTLAPGQIDPEATCPACSLDVSHQVSTLVRRYE 1232
+ ++ E++L ++ + + +K GQ++ ++ +L
Sbjct: 398 EIVKSRCENLLHKNNQI---TKTKNKNVEKMRGQMESHLK------ELERVCDSLTAAER 448
Query: 1233 QLQDMVNSLAVSRPSKKAKLQRQDEELLGRVQSAILQVQGDCEKLNITTSNLIEDHRQKQ 1292
+L + SL + K A + EL G QV G+ L T +L E++ Q
Sbjct: 449 RLHECQESLQCCK-GKCADQEHTIRELQG-------QVDGNHNLL--TKLSLEEENCLIQ 498
Query: 1293 KDIAMLYQGLEK-------LEKEKANREHLEMEIDVK-ADKSALATKVSRVQFDATTEQL 1344
L Q LE+ LEK+ AN+E ++K +KSA T ++R Q +A E+
Sbjct: 499 LKCENLQQKLEQMDAENKELEKKLANQEECLKHSNLKFKEKSAEYTALAR-QLEAALEEG 557
Query: 1345 NHMMQELVAKMSGQEQDWQKMLDRLLTEMDNK 1376
+ E + KMS +E Q + L TE+ K
Sbjct: 558 RQKVAEEIEKMSSRESALQIKILDLETELRKK 589
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 50.1 bits (118), Expect = 2e-05
Identities = 110/499 (22%), Positives = 209/499 (41%), Gaps = 64/499 (12%)
Query: 1027 AVETFHLMGELSSLYVGLKESMKDLDEEQAGQTDLEKIQFLLAQMVKRTIPPELQEQLKT 1086
+ ET M + + +KE+ L++ +A + +LE+ L Q K + ++Q +
Sbjct: 844 SAETEKEMATMKEEFGRIKET---LEKSEARRKELEEKMVSLLQE-KNDLQLQVQAEQDN 899
Query: 1087 VKT-------LAKEVWQEKAKVERLQRILEGEGNQEAGKELKAGELRLQLGVLRVTVADI 1139
+ L K Q +AKV+ + LE E A K +L + L+ + D+
Sbjct: 900 LNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDL 959
Query: 1140 EKELAELRESQDRGKAAMENSVSEASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKA 1199
E LA++ ++ K A EN V L +++ L II + L +A
Sbjct: 960 ELTLAKV----EKEKHATENKVKN----LTEEMAGLDEIIAKLTKEKKAL-------QEA 1004
Query: 1200 HTLAPGQIDPEATCPACSLDVSHQVSTLVRRYEQLQDMVNSLAVSRPSKKAKLQRQDEEL 1259
H A + E V+ + V+ +Q+ D+ SL + + L+R +L
Sbjct: 1005 HQQALDDLQVEED------KVNSLSKSKVKLEQQVDDLEGSLEQEK-KVRMDLERAKRKL 1057
Query: 1260 LGRV---QSAILQVQGDC----EKLNITTSNLIEDHRQKQKDIAMLYQGLEKLEKEKANR 1312
G + Q +I+ ++ D EKL ++ + + + + + + Q +KL++ +A
Sbjct: 1058 EGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARI 1117
Query: 1313 EHLEMEIDVKADKSALATKVSRVQFDAT--TEQLNHMMQELVAKMSGQ-------EQDWQ 1363
E LE E++ A+++A A KV +++ D + E+++ ++E S Q E ++Q
Sbjct: 1118 EELEEELE--AERTARA-KVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQ 1174
Query: 1364 KM---LDRLLTEMD---NKLDRLELDPVKQLLE--DRWKSLRQQLRERPPLYQA---DEA 1412
KM L+ + + L + D V +L E D + ++Q+L + ++ D
Sbjct: 1175 KMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVT 1234
Query: 1413 AAMRRQLLAHFHCLSCDRPLETPVTGHAIPVTPAGPGLPGHHSIRPYTVFEL-EQVRQHS 1471
+ M + + A + R LE + + + A L + R E E RQ
Sbjct: 1235 SNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLE 1294
Query: 1472 RNLKLGSAFPRGDLAQMEQ 1490
L S RG L+ +Q
Sbjct: 1295 EKEALISQLTRGKLSYTQQ 1313
Score = 45.8 bits (107), Expect = 3e-04
Identities = 94/477 (19%), Positives = 187/477 (39%), Gaps = 72/477 (15%)
Query: 976 IPAQKAPGQDVTLFRSPDSVDRVLSEGSEVSSEVLSERRNSLRRMSSSFPTAVETFHLMG 1035
+ +++ L + + D++L+E + E SE +S + S L
Sbjct: 1432 VDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARS----------LST 1481
Query: 1036 ELSSLYVGLKESMKDLDEEQAGQTDL-EKIQFLLAQMVKRTIPPELQEQLKTVKTLAKEV 1094
EL L +ES++ L+ + +L E+I L Q+ E + + ++ + K++
Sbjct: 1482 ELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQL------GEGGKNVHELEKVRKQL 1535
Query: 1095 WQEKAKVERLQRILEGEGNQEAGKELKAGELRLQLGVLRVTVADIEKELAELRESQDRGK 1154
EK +++ E E GK L+A +L+ ++ A+IE++LAE E ++ K
Sbjct: 1536 EVEKLELQSALEEAEASLEHEEGKILRA---QLEFNQIK---AEIERKLAEKDEEMEQAK 1589
Query: 1155 AAMENSVSEASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAHTLAPGQIDPEATCP 1214
+ V L + ++ L M + A+ +A +
Sbjct: 1590 RNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQ 1649
Query: 1215 ACSLDVSHQVSTLVRRYEQLQDMV------NSL----------AVSRPSKKAKLQRQDE- 1257
+ D Q+ VR + L++ + N+L V + + KL Q+
Sbjct: 1650 SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELI 1709
Query: 1258 ELLGRVQ-----------------SAILQVQGDCEKLNITTSNLIEDHRQKQKDIAMLYQ 1300
E RVQ S + Q+Q + E+ N E ++ D AM+ +
Sbjct: 1710 ETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAE 1769
Query: 1301 GLEK-------LEKEKANREHLEMEIDVKADKS-ALATKVSRVQFDATTEQLNHMMQELV 1352
L+K LE+ K N E ++ + D++ +A K + Q ++ + EL
Sbjct: 1770 ELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELE 1829
Query: 1353 A--KMSGQEQDWQKMLDRLLTEM-----DNKLDRLELDPVKQLLEDRWKSLRQQLRE 1402
A K + + + +R + E+ ++K + L L + L+ + K+ ++Q E
Sbjct: 1830 AEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEE 1886
Score = 45.4 bits (106), Expect = 4e-04
Identities = 79/398 (19%), Positives = 165/398 (41%), Gaps = 46/398 (11%)
Query: 1034 MGELSSLYVGLKESMKDLDEEQAG-QTDLEKIQFLLAQMVKRTIPPELQEQLKTVKTLAK 1092
+ EL L+ + L++E++ + +L+ + + Q++K E K +TL
Sbjct: 1202 VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLE-----KVSRTLED 1256
Query: 1093 EVWQEKAKVERLQRILEGEGNQEAGKELKAGELRLQLGVLRVTVADIEK-------ELAE 1145
+ + + K+E QR L Q A + + GEL QL ++ + + ++ +
Sbjct: 1257 QANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMED 1316
Query: 1146 L-RESQDRGKAAMENSVSEASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAHTLAP 1204
L R+ ++ GKA +N+++ A + D LR E + + L + +
Sbjct: 1317 LKRQLEEEGKA--KNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWR 1374
Query: 1205 GQIDPEATCPACSL-DVSHQVSTLVRRYEQLQDMVNSLAVSRPSKKAKLQRQDEELLGRV 1263
+ + +A L + +++ ++ E+ + VN+ S K +LQ + E+L+
Sbjct: 1375 TKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLM--- 1431
Query: 1264 QSAILQVQGDCEKLNITTSNLIEDHRQKQKDIAMLYQGLE--KLEKEKANREHLEMEIDV 1321
D E+ N + L + R K +A Q E + E E + +E + ++
Sbjct: 1432 --------VDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1483
Query: 1322 KADKSALATKVSRVQFDATTEQLNHMMQELVAKMSGQEQDWQKMLDRLLTEMDNKLDRLE 1381
K+A + ++ T ++ N +QE ++ ++ Q + K + E
Sbjct: 1484 FKLKNAYEESLEHLE---TFKRENKNLQEEISDLTEQLGEGGKNVH-------------E 1527
Query: 1382 LDPVKQLLEDRWKSLRQQLRERPPLYQADEAAAMRRQL 1419
L+ V++ LE L+ L E + +E +R QL
Sbjct: 1528 LEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQL 1565
Score = 31.2 bits (69), Expect = 8.8
Identities = 49/235 (20%), Positives = 97/235 (41%), Gaps = 48/235 (20%)
Query: 1051 LDEEQAGQTDLEKIQFLLAQMVK--RTIPPELQEQLKTVKTLAKEVWQEK---AKVERLQ 1105
+++++ ++DL ++Q + + V+ R + ++ + +A+E+ +E+ A +ER++
Sbjct: 1726 INQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMK 1785
Query: 1106 RILE----------GEGNQEAGKELKAGELRLQLGVLRVTVADIEKELAELRESQD-RGK 1154
+ +E E Q A LK G+ +LQ RV + E E + R ++ +G
Sbjct: 1786 KNMEQTIKDLQHRLDEAEQIA---LKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGM 1842
Query: 1155 AAMENSVSEAS----------LYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAHTLAP 1204
E + E + L LQD +DKL++ + KA+
Sbjct: 1843 RKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKV------------------KAYKRQA 1884
Query: 1205 GQIDPEATCPACSL-DVSHQVSTLVRRYEQLQDMVNSLAVSRPSKKAKLQRQDEE 1258
+ + +A V H++ R + + VN L AK + DEE
Sbjct: 1885 EEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGAKQKMHDEE 1939
>gi|7705415 hook homolog 1 [Homo sapiens]
Length = 728
Score = 49.7 bits (117), Expect = 2e-05
Identities = 93/412 (22%), Positives = 173/412 (41%), Gaps = 68/412 (16%)
Query: 1054 EQAGQTDLEKIQFLLAQMVK-RTIPPELQEQLKTVK----TLAKEVWQEKAKVERLQRIL 1108
EQ + LE++Q LA+ + R EL Q+ T++ +L E K+++L
Sbjct: 177 EQQLKRALEELQEALAEKEELRQRCEELDMQVTTLQDEKNSLVSENEMMNEKLDQLDGSF 236
Query: 1109 EGEGNQEAGK---------ELKAGELRLQLGV--LRVTVADIEKELAELRESQDRGKAAM 1157
+ A K +L+ RL+ RV ++EK+L E + D
Sbjct: 237 DDPNTVVAKKYFHAQLQLEQLQEENFRLEAAKDDYRVHCEELEKQLIEFQHRNDE----- 291
Query: 1158 ENSVSEASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAHTLAPGQIDPEATCPACS 1217
S++E + L+D++D LR + ST+ + K L
Sbjct: 292 LTSLAEETRALKDEIDVLRATSDKANKLESTV---EIYRQKLQDLN-------------- 334
Query: 1218 LDVSHQVSTLVRRYEQLQDMVNSLAVSRPSKKAKLQRQDEELLGR-VQSAILQVQGDCEK 1276
D+ QV TL + + M N++++ KKA R E R VQ +++ + ++
Sbjct: 335 -DLRKQVKTL--QETNMMYMHNTVSLEEELKKANAARTQLETYKRQVQDLHVKLSSESKR 391
Query: 1277 ---LNITTSNLIEDH----RQKQKDIAM---LYQGLEKLEKEKANREHLEMEIDVKADKS 1326
L L E H ++K++ I L + E+L + ++HL + D A KS
Sbjct: 392 ADTLAFEMKRLEEKHEALLKEKERLIEQRDTLKETNEELRCSQVQQDHLN-QTDASATKS 450
Query: 1327 A--LATKVSRVQFDATTEQLNHMMQELVAKMSGQEQDWQKMLDRLLTEMDNKLDRLELDP 1384
LA ++ V++ +L H + L + G E + + L L + K++ LE +
Sbjct: 451 YENLAAEIMPVEYREVFIRLQHENKMLRLQQEGSENERIEELQEQLEQKHRKMNELETEQ 510
Query: 1385 ---------VKQLLEDRWKSLRQQLRERPPLYQADEAAAMRRQLLAHFHCLS 1427
++Q +ED KSL++Q + + + ++ ++++L AH L+
Sbjct: 511 RLSKERIRELQQQIEDLQKSLQEQGSKS----EGESSSKLKQKLEAHMEKLT 558
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.133 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,431,853
Number of Sequences: 37866
Number of extensions: 4073931
Number of successful extensions: 13793
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 540
Number of HSP's that attempted gapping in prelim test: 10894
Number of HSP's gapped (non-prelim): 2118
length of query: 1663
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1547
effective length of database: 13,855,062
effective search space: 21433780914
effective search space used: 21433780914
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.