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Search of human proteins with 14149789
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14149789 hypothetical protein LOC84070 [Homo sapiens]
(893 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14149789 hypothetical protein LOC84070 [Homo sapiens] 1780 0.0
gi|224458301 family with sequence similarity 186, member A [Homo... 159 1e-38
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 58 4e-08
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 58 4e-08
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 57 1e-07
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 55 2e-07
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 55 2e-07
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 54 5e-07
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 54 6e-07
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 54 6e-07
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 53 1e-06
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 53 1e-06
gi|148746195 trichohyalin [Homo sapiens] 53 1e-06
gi|21735548 centrosomal protein 2 [Homo sapiens] 50 7e-06
gi|221219020 NYD-SP11 protein [Homo sapiens] 49 2e-05
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 48 4e-05
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 47 8e-05
gi|38176300 nestin [Homo sapiens] 46 2e-04
gi|219803769 trichoplein [Homo sapiens] 46 2e-04
gi|14150056 trichoplein [Homo sapiens] 46 2e-04
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 45 3e-04
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 45 3e-04
gi|223005859 WD repeat domain 67 isoform 1 [Homo sapiens] 45 4e-04
gi|7661936 scaffold attachment factor B2 [Homo sapiens] 45 4e-04
gi|31563330 A-kinase anchor protein 13 isoform 1 [Homo sapiens] 44 7e-04
gi|21493031 A-kinase anchor protein 13 isoform 3 [Homo sapiens] 44 7e-04
gi|21493029 A-kinase anchor protein 13 isoform 2 [Homo sapiens] 44 7e-04
gi|94721321 coiled-coil domain containing 11 [Homo sapiens] 44 7e-04
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 44 9e-04
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 43 0.001
>gi|14149789 hypothetical protein LOC84070 [Homo sapiens]
Length = 893
Score = 1780 bits (4610), Expect = 0.0
Identities = 893/893 (100%), Positives = 893/893 (100%)
Query: 1 MEKDDPPQLVTPTSVKAIILRIEAAQLTRAQEDISTQLSDILDNVNCVINRFQEELGYDL 60
MEKDDPPQLVTPTSVKAIILRIEAAQLTRAQEDISTQLSDILDNVNCVINRFQEELGYDL
Sbjct: 1 MEKDDPPQLVTPTSVKAIILRIEAAQLTRAQEDISTQLSDILDNVNCVINRFQEELGYDL 60
Query: 61 KENAKSQQRDPKGKKRFILLEKIASFSKDAMMKEKHLYDILRWLGDWGDTLTYEIGPRKS 120
KENAKSQQRDPKGKKRFILLEKIASFSKDAMMKEKHLYDILRWLGDWGDTLTYEIGPRKS
Sbjct: 61 KENAKSQQRDPKGKKRFILLEKIASFSKDAMMKEKHLYDILRWLGDWGDTLTYEIGPRKS 120
Query: 121 EEEAAALDEWIEVTEKVLPLSLIATKRGIESLTALCSTLIEGQKKRSQVSKRTFWQGWQG 180
EEEAAALDEWIEVTEKVLPLSLIATKRGIESLTALCSTLIEGQKKRSQVSKRTFWQGWQG
Sbjct: 121 EEEAAALDEWIEVTEKVLPLSLIATKRGIESLTALCSTLIEGQKKRSQVSKRTFWQGWQG 180
Query: 181 RSPQTSPSHPQPLSPEQMLQDQHTMNTKASEVTSMLQELLDSTMFSKGEVRAIRYMATVV 240
RSPQTSPSHPQPLSPEQMLQDQHTMNTKASEVTSMLQELLDSTMFSKGEVRAIRYMATVV
Sbjct: 181 RSPQTSPSHPQPLSPEQMLQDQHTMNTKASEVTSMLQELLDSTMFSKGEVRAIRYMATVV 240
Query: 241 ENLNKALILQHKENRSLETKYRHLQMQATKELSSQRLHFQQFMEVLESRRDALLKQVEIL 300
ENLNKALILQHKENRSLETKYRHLQMQATKELSSQRLHFQQFMEVLESRRDALLKQVEIL
Sbjct: 241 ENLNKALILQHKENRSLETKYRHLQMQATKELSSQRLHFQQFMEVLESRRDALLKQVEIL 300
Query: 301 GGRYHDLLLMKQALEFQLKKAQNATGQAEDLAEVSVDSPGPSERETLPRKETVMEESQQE 360
GGRYHDLLLMKQALEFQLKKAQNATGQAEDLAEVSVDSPGPSERETLPRKETVMEESQQE
Sbjct: 301 GGRYHDLLLMKQALEFQLKKAQNATGQAEDLAEVSVDSPGPSERETLPRKETVMEESQQE 360
Query: 361 PMKEEQLFSPLPPSPMAMIRDSGAIAAGHQPLSTMTVRSRVADVFGSKDTESLEPVLLPL 420
PMKEEQLFSPLPPSPMAMIRDSGAIAAGHQPLSTMTVRSRVADVFGSKDTESLEPVLLPL
Sbjct: 361 PMKEEQLFSPLPPSPMAMIRDSGAIAAGHQPLSTMTVRSRVADVFGSKDTESLEPVLLPL 420
Query: 421 VDRRFPKKWERPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPW 480
VDRRFPKKWERPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPW
Sbjct: 421 VDRRFPKKWERPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPW 480
Query: 481 EEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKE 540
EEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKE
Sbjct: 481 EEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKE 540
Query: 541 QESPRREPEQLGEDVERRIFTPTSRWRDLEKAELSLVPAPSRTQSAHQSRRPHLPMSPST 600
QESPRREPEQLGEDVERRIFTPTSRWRDLEKAELSLVPAPSRTQSAHQSRRPHLPMSPST
Sbjct: 541 QESPRREPEQLGEDVERRIFTPTSRWRDLEKAELSLVPAPSRTQSAHQSRRPHLPMSPST 600
Query: 601 QQPALGKQRPMSSVEFTYRPRTRRVPTKPKKSASFPVTGTSIRRLTWPSLQISPANIKKK 660
QQPALGKQRPMSSVEFTYRPRTRRVPTKPKKSASFPVTGTSIRRLTWPSLQISPANIKKK
Sbjct: 601 QQPALGKQRPMSSVEFTYRPRTRRVPTKPKKSASFPVTGTSIRRLTWPSLQISPANIKKK 660
Query: 661 VYHMDMEAQRKNLQLLSEESELRLPHYLRSKALELTTTTMELGALRLQYLCHKYIFYRRL 720
VYHMDMEAQRKNLQLLSEESELRLPHYLRSKALELTTTTMELGALRLQYLCHKYIFYRRL
Sbjct: 661 VYHMDMEAQRKNLQLLSEESELRLPHYLRSKALELTTTTMELGALRLQYLCHKYIFYRRL 720
Query: 721 QSLRQEAINHVQIMKETEASYKAQNLYIFLENIDRLQSLRLQAWTDKQKGLEEKHRECLS 780
QSLRQEAINHVQIMKETEASYKAQNLYIFLENIDRLQSLRLQAWTDKQKGLEEKHRECLS
Sbjct: 721 QSLRQEAINHVQIMKETEASYKAQNLYIFLENIDRLQSLRLQAWTDKQKGLEEKHRECLS 780
Query: 781 SMVTMFPKLQLEWNVHLNIPEVTSPKPKKCKLPAASPRHIRPSGPTYKQPFLSRHRACVP 840
SMVTMFPKLQLEWNVHLNIPEVTSPKPKKCKLPAASPRHIRPSGPTYKQPFLSRHRACVP
Sbjct: 781 SMVTMFPKLQLEWNVHLNIPEVTSPKPKKCKLPAASPRHIRPSGPTYKQPFLSRHRACVP 840
Query: 841 LQMARQQGKQMEAVWKTEVASSSYAIEKKTPASLPRDQLRGHPDIPRLLTLDV 893
LQMARQQGKQMEAVWKTEVASSSYAIEKKTPASLPRDQLRGHPDIPRLLTLDV
Sbjct: 841 LQMARQQGKQMEAVWKTEVASSSYAIEKKTPASLPRDQLRGHPDIPRLLTLDV 893
>gi|224458301 family with sequence similarity 186, member A [Homo
sapiens]
Length = 2351
Score = 159 bits (401), Expect = 1e-38
Identities = 124/372 (33%), Positives = 195/372 (52%), Gaps = 42/372 (11%)
Query: 7 PQLVTPTSVKAIILRIEAAQLTRAQEDISTQLSDILDNVNCVINRFQEELGYDLKENAKS 66
P L P SVK II RIE AQL RA+EDI QLS+I++NV+ ++ R Y L N+ S
Sbjct: 39 PNLEIPFSVKDIISRIERAQLHRAREDIDMQLSEIMNNVHRIMTR------YTLVFNSSS 92
Query: 67 QQR----DPKGKKRFILLEKIASFSKDAMMKEKHLYDILRWLGDWGDTLTYEIGPRKSEE 122
++ + K K+R LEK+A+++K ++EK L +IL WL +W D L SE
Sbjct: 93 ERNVSLTEHKKKQRTNFLEKMATYAKTIEIREKTLANILAWLEEWNDVL--------SEM 144
Query: 123 EAAALDE---WIEVTEKVLPLSLIATKRGIESLTALCSTLIEGQKKRSQ--VSKRTFWQG 177
+DE WI E +LP +L A + ++ L+ ++ ++ +KK+ + +S+ T W+
Sbjct: 145 TLMDVDEHHHWIAQME-LLPDTLKAIENNVKILSRFSTSFLDEKKKQKKKILSRGTLWKS 203
Query: 178 WQGRSPQTSPSHPQPLSPEQMLQDQHTMNTKASEVTSMLQELLDSTMFSKGEVRAIRYMA 237
W+ R + PS + L P+QM+ DQ NTK SE+ MLQEL+ +TMFS E AI+Y++
Sbjct: 204 WKERVIKR-PSTARALRPDQMISDQLATNTKVSEIQGMLQELIGTTMFSTLENNAIKYIS 262
Query: 238 TVVENLNKALILQHKE----NRSLETKYRHLQMQATKE--------LSSQRLHFQQFMEV 285
+ + NL+ AL + + E N T Y H +A KE LS++ QQ ++
Sbjct: 263 STIVNLSTALSMLNDELKCVNFQSSTVYAHETSEAEKELSLKIIRDLSNENEMLQQKLQD 322
Query: 286 LESRRDALLKQVEILGGRYHDL-----LLMKQALEFQLKKAQNATGQAEDLAEVSVDSPG 340
E + + L++ ++ Y L L + Q +A G ED + +D
Sbjct: 323 AEEKCEQLIRSKIVIEQLYAKLSTSSTLKVLPGPSPQSSRAIIKVGDTEDNMDNILDKEL 382
Query: 341 PSERETLPRKET 352
+ + + RKET
Sbjct: 383 ENIVDEVQRKET 394
Score = 133 bits (334), Expect = 8e-31
Identities = 82/244 (33%), Positives = 134/244 (54%), Gaps = 11/244 (4%)
Query: 653 SPANIKKKVYHMDMEAQRKNLQLLSEESEL-RLPHYLRSKALELTTTTMELGALRLQYLC 711
SP +++K Y +D+EAQ+KNL LL++ + LP L + A L + + ++L YL
Sbjct: 2096 SPQELEEKRYFVDVEAQKKNLILLNQAIKTCGLPSQLHTMARTLIIEILHMDTVQLGYLF 2155
Query: 712 HKYIFYRRLQSLRQEAINHVQIMKETEASYKAQNLYIFLENIDRLQSLRLQAWTDKQKGL 771
KYI YR +Q R + ++ ++ T Y+A+NL++ L +D +Q WT+KQK L
Sbjct: 2156 RKYIAYRLIQHARNNIMKRLKAIQNTGKGYEARNLHMMLSRLDDYGKKVMQVWTEKQKSL 2215
Query: 772 EEKHRECLSSMVTMFPKLQL--EWNVHLNIPEVTSPKPKKCKLPAASPRHIRPSGPTYKQ 829
+K +CL M+ +F +L+ E N+ IP + K ++PA++ +P + +
Sbjct: 2216 GQKRNQCLKKMIHVFNQLKKIHELNLSQPIPLIIEEK----QIPASTTFVQKP----FLK 2267
Query: 830 PFLSRHRACVPLQMARQQGKQMEAVWKTEVASSSYAIEKKTPASLPRDQLRGHPDIPRLL 889
+ R + RQQ Q EA+W ++++SSY I +KT QL G+PDIPRLL
Sbjct: 2268 LLMEEDRTSDICKKFRQQEDQTEAIWNVDLSTSSYPIAEKTSMHSLWAQLGGYPDIPRLL 2327
Query: 890 TLDV 893
L+V
Sbjct: 2328 QLEV 2331
Score = 54.3 bits (129), Expect = 5e-07
Identities = 116/555 (20%), Positives = 221/555 (39%), Gaps = 113/555 (20%)
Query: 193 LSPEQMLQDQHTMNTKASEVTSMLQELLDSTMFSKGEVRAIRYMATVVENLNKALILQHK 252
+ P M+Q T + ++ + T+ SK E + E L K + H+
Sbjct: 586 VEPLSMIQFDDTAEPQKGKIKGKKHHISSGTITSKEEKTEEK------EELTKQ-VKSHQ 638
Query: 253 ENRSLETKYRHLQMQATKELSS-----QRLHFQQFMEVLESRRDALLKQ-VEILGGRYHD 306
+SL + ++T+ L S ++ + ++F E + A LKQ ++ +G +
Sbjct: 639 LVKSLSRVAKETS-ESTRVLESPDGKSEQSNLEEFQEAIM----AFLKQKIDNIGKAFDK 693
Query: 307 LLLMKQALEFQLKKAQNATGQAEDLAEVSVDSPGPSERETLPR-----KETVMEESQQE- 360
+ K+ E LK+A+ + + + ++ ET+ + K+T EE E
Sbjct: 694 KTVPKE--EELLKRAE---AEKLGIIKAKMEEYFQKVAETVTKILRKYKDTKKEEQVGEK 748
Query: 361 PMKEEQLFSPLPPSPMAMIRDSGAIAAGHQPLSTMTVRSRVADVFGSKDTESLEPVLLPL 420
P+K++++ S +P H S ++ +S + + + T+ + L+ +
Sbjct: 749 PIKQKKVVSFMPGL--------------HFQKSPISAKSESSTLLSYESTDPVINNLIQM 794
Query: 421 VDRRFPKKWERPVAESL--GHKDKD---QEDYFQKGGLQIKFHCSKQLSLESSRQVTSES 475
+ + + P ++ HK+K+ QE Y Q+G Q+ KQ L R + E
Sbjct: 795 ILAEIESERDIPTVSTVQKDHKEKEKQRQEQYLQEGQEQMSGMSLKQ-QLLGERNLLKEH 853
Query: 476 QE---EPWEE--------EFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLE 524
E E WEE E +E + Q +EEEMW++ QK+ + E +EK +Q E
Sbjct: 854 YEKISENWEEKKAWLQMKEGKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQRGQE 913
Query: 525 D------------------------LAREQ-QRRWVQLEKEQESPRR---------EPEQ 550
+ L +E Q R +Q E + P R +PE+
Sbjct: 914 EEELPKSSLQRLEEGTQKMKTQGLLLEKENGQMRQIQKEAKHLGPHRRREKGKEKQKPER 973
Query: 551 LGEDVERRIFTPTS-RWRDLEKAELS--LVPAPSRTQSAHQSRRPHLPMSPSTQQPALGK 607
ED+ER+I T + ++ + EL ++ P + +SP +
Sbjct: 974 GLEDLERQIKTKDQMQMKETQPKELEKMVIQTP-------------MTLSPRWKSVLKDV 1020
Query: 608 QRPMSSVEFTYRPRTRRVPTKPKKSASFPVTGTSIRRLTWP-SLQISPANIKKKVYHMDM 666
QR EF +T + P + +T + + P +L IS + K ++
Sbjct: 1021 QRSYEGKEFQRNLKT--LENLPDEKEPISITPPPSLQYSLPGALPISGQPLTKCIHLTPQ 1078
Query: 667 EAQRKNLQLLSEESE 681
+AQ + L ++++
Sbjct: 1079 QAQEVGITLTPQQAQ 1093
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 57.8 bits (138), Expect = 4e-08
Identities = 127/690 (18%), Positives = 276/690 (40%), Gaps = 96/690 (13%)
Query: 199 LQDQHTMNTKASEVTSMLQELLDSTMFSKGEVRAIRYMATVVENLNKALILQHKENRSLE 258
L +Q + + +E+ + L S + +++ + +ENL K + KE
Sbjct: 912 LLEQKELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEK----ECKEKEEKI 967
Query: 259 TKYRHLQMQATKELSSQRLHFQQFMEVLESRR------DALLKQVEILGGRYHDLLL--- 309
K + + ++A KEL S R Q E LES R A ++ + Y +LLL
Sbjct: 968 NKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYE 1027
Query: 310 -MKQALEFQLKKAQNATGQAEDLAEVSVDSPGPSERETLPRKETVMEESQQEPMKEEQLF 368
+ L+ + ++A N + EDL R + + ET+ +++ + E L
Sbjct: 1028 KQSEQLDVEKERANNFEHRIEDLTR--------QLRNSTLQCETINSDNEDLLARIETLQ 1079
Query: 369 SPLPPSPMAMIRDSGAIAAGHQPLSTMTVRSRVADVFGSKDTESLEPVLLPLVDRRFPKK 428
S + ++ A A + L ++ + LE + + L +K
Sbjct: 1080 SNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQL------QK 1133
Query: 429 WERPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQE-EPWEEEFGRE 487
++ + +++ + ++D Q + ++ ++L E ++++T+++ + E E+E +
Sbjct: 1134 EKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQ 1193
Query: 488 MRRQLWLEEE--------EMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEK 539
++Q L+EE + ++++ K L + +++L +++ + + L+
Sbjct: 1194 KQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELAD------SKQAETDHLILQA 1247
Query: 540 EQESPRREPEQLGEDVERRIFTPTSRWRDLEKAELSLVPAPSRTQSAHQSRRPHLPMSPS 599
+ +Q E + ++ TS + + + RT SA+Q R L
Sbjct: 1248 SLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQRTLSAYQQRVTAL---QE 1304
Query: 600 TQQPALGKQRPMSSVEFTYRPRTRRVPTKPKKSASFPVTGTSIRRLTWPSLQISPANIKK 659
+ A +Q ++S +Y+ R V K +K+ S Q K+
Sbjct: 1305 ECRAAKAEQATVTSEFESYKVRVHNV-LKQQKNKSMS--------------QAETEGAKQ 1349
Query: 660 KVYHMDMEAQRKNLQLLSEESELRLPHYLRSKALELTTTTMELGALRLQYLCHKYIFYRR 719
+ H++M + ++L ++ L++ EL T E L R
Sbjct: 1350 EREHLEMLIDQLKIKLQDSQNNLQI------NVSELQTLQSEHDTL-----------LER 1392
Query: 720 LQSLRQEAINHVQIMKETEASYKAQNLYIFLENIDRLQSLRLQ------AWTDKQKGLEE 773
+ QE ++ ++E S +++N+ + E+ + L Q ++ D+ + L+E
Sbjct: 1393 HNKMLQETVSKEAELREKLCSIQSENMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRHLQE 1452
Query: 774 KHRECLSSMVTMFPKLQLEWNVHLNIPEVTSPKPKKCKLPAASPRHIRPSGPTYKQPFLS 833
+HR+ + ++ K++ + N P SP + L +++R T P L
Sbjct: 1453 EHRKTVETLQQQLSKMEAQLFQLKNEPTTRSPVSSQQSL-----KNLRERRNT-DLPLLD 1506
Query: 834 RHRACVPLQMARQQGKQMEAVWKTEVASSS 863
H + R++G+ ME V+S+S
Sbjct: 1507 MH------TVTREEGEGMETTDTESVSSAS 1530
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 57.8 bits (138), Expect = 4e-08
Identities = 31/124 (25%), Positives = 69/124 (55%), Gaps = 7/124 (5%)
Query: 440 KDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEE--PWEEEFGREMRRQLWLEEE 497
K K+Q + ++ G Q + ++ + + E +E+ EE+ G++ Q+W ++E
Sbjct: 280 KQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQ-EEQMWEQKE 338
Query: 498 EMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQ----RRWVQLEKEQESPRREPEQLGE 553
+MW+Q+++ W EQ +++ + E+ R+Q+ ++ Q+ K++E R++ EQ+GE
Sbjct: 339 QMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGE 398
Query: 554 DVER 557
E+
Sbjct: 399 QKEQ 402
Score = 46.2 bits (108), Expect = 1e-04
Identities = 43/242 (17%), Positives = 101/242 (41%), Gaps = 17/242 (7%)
Query: 315 EFQLKKAQNATGQAEDLAEVSVDSPGPSERETLPRKETVMEESQQEPMKEEQLFSPLPPS 374
E Q++K + G+ E+ + G E + ++E V ++ +Q +EEQ
Sbjct: 212 EEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQ-------- 263
Query: 375 PMAMIRDSGAIAAGHQPLSTMTVRSRVADVFGSKDTESLEPVLLPLVDRRFPKKWERPVA 434
M + + + ++ + G ++ + E ++ E +
Sbjct: 264 ---MREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMR 320
Query: 435 ESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWEEEFGREMRRQLWL 494
E K +E +++ + + K+ + Q+ + ++ +EE R+ Q+
Sbjct: 321 EQEEQMGKQEEQMWEQ---KEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRK 377
Query: 495 EEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKEQESPRREPEQLGED 554
+EE+M +Q ++ EQ ++K + ++ REQ+ Q+ +++E R++ E +GE
Sbjct: 378 QEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEE---QMGEQKEQMRKQEEHMGEQ 434
Query: 555 VE 556
E
Sbjct: 435 KE 436
Score = 45.1 bits (105), Expect = 3e-04
Identities = 33/142 (23%), Positives = 67/142 (47%), Gaps = 6/142 (4%)
Query: 435 ESLGHKDKD-QEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWEEEFGREMRRQLW 493
E +G +++ Q+ Q G + + ++ E QV + ++ +EE R+ Q+
Sbjct: 206 EQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMR 265
Query: 494 LEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRW----VQLEKEQESPRREPE 549
+EE+M +Q ++ EQ QE+ + E+ REQ+ + Q+ +++E R + E
Sbjct: 266 EQEEQMREQEEQMLKQKEQTEQEE-QTGEQEEQMREQEEQMREQEEQMREQEEQMREQEE 324
Query: 550 QLGEDVERRIFTPTSRWRDLEK 571
Q+G+ E+ W E+
Sbjct: 325 QMGKQEEQMWEQKEQMWEQKEQ 346
Score = 38.1 bits (87), Expect = 0.037
Identities = 24/98 (24%), Positives = 50/98 (51%), Gaps = 4/98 (4%)
Query: 462 QLSLESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQW 521
Q+ + + E Q EE+ G E Q+ +EE+M +Q ++ + +QE Q ++
Sbjct: 186 QVREQEGQMGEQEGQMGEQEEQMG-EQEEQMQKQEEQMGEQEEQ---MRKQEEQMGEQEE 241
Query: 522 NLEDLAREQQRRWVQLEKEQESPRREPEQLGEDVERRI 559
++ + Q++ Q+ K++E R + EQ+ E E+ +
Sbjct: 242 QVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQML 279
Score = 37.7 bits (86), Expect = 0.048
Identities = 25/99 (25%), Positives = 49/99 (49%), Gaps = 4/99 (4%)
Query: 462 QLSLESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQW 521
Q+ + + E Q + EE+ G E Q+ +EE+M +Q ++ EQ +++ +
Sbjct: 200 QMGEQEEQMGEQEEQMQKQEEQMG-EQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMR 258
Query: 522 NLEDLAREQQRRWVQLEKE---QESPRREPEQLGEDVER 557
E+ REQ+ + + E++ Q+ + EQ GE E+
Sbjct: 259 KQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQ 297
Score = 36.6 bits (83), Expect = 0.11
Identities = 23/88 (26%), Positives = 49/88 (55%), Gaps = 5/88 (5%)
Query: 474 ESQEEPWEEEFGREMRRQLWLEEEEMWQQ----RQKKWALLEQEHQEKLRQWNLEDLARE 529
E Q E + G E Q+ +EE+M +Q ++++ + EQE Q + ++ + + +
Sbjct: 184 EGQVREQEGQMG-EQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQ 242
Query: 530 QQRRWVQLEKEQESPRREPEQLGEDVER 557
Q++ Q++K++E R++ EQ+ E E+
Sbjct: 243 VQKQEEQVQKQEEQMRKQEEQMREQEEQ 270
Score = 35.0 bits (79), Expect = 0.31
Identities = 22/82 (26%), Positives = 45/82 (54%), Gaps = 1/82 (1%)
Query: 476 QEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWV 535
QE E+ G ++R Q E+ Q R+++ + EQE Q ++ + + + Q++
Sbjct: 162 QEGQVREQEG-QVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEE 220
Query: 536 QLEKEQESPRREPEQLGEDVER 557
Q+ +++E R++ EQ+GE E+
Sbjct: 221 QMGEQEEQMRKQEEQMGEQEEQ 242
Score = 34.3 bits (77), Expect = 0.53
Identities = 28/145 (19%), Positives = 70/145 (48%), Gaps = 8/145 (5%)
Query: 427 KKWERPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWEEEFGR 486
++ E + E G + +E Q G + + ++ E Q+ + ++ +EE +
Sbjct: 188 REQEGQMGEQEGQMGEQEE---QMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQ 244
Query: 487 EMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKEQESPRR 546
+ Q+ +EE+M ++++++ +E +E++R+ + L +++Q + EQE R
Sbjct: 245 KQEEQVQKQEEQM-RKQEEQM----REQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMR 299
Query: 547 EPEQLGEDVERRIFTPTSRWRDLEK 571
E E+ + E ++ + R+ E+
Sbjct: 300 EQEEQMREQEEQMREQEEQMREQEE 324
Score = 31.6 bits (70), Expect = 3.4
Identities = 20/82 (24%), Positives = 44/82 (53%), Gaps = 1/82 (1%)
Query: 476 QEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWV 535
QE E+ G ++R Q E+ Q R+++ + EQE Q + ++ + + + +
Sbjct: 148 QEGQVREQEG-QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEE 206
Query: 536 QLEKEQESPRREPEQLGEDVER 557
Q+ +++E +++ EQ+GE E+
Sbjct: 207 QMGEQEEQMQKQEEQMGEQEEQ 228
Score = 30.8 bits (68), Expect = 5.9
Identities = 36/207 (17%), Positives = 85/207 (41%), Gaps = 9/207 (4%)
Query: 164 KKRSQVSKRTFWQGWQGRSPQTSPSHPQPLSPEQMLQDQHTMNTKASEVTSMLQELLDST 223
++ Q+ K+ G Q Q Q EQM + + M + ++ +++L
Sbjct: 224 EQEEQMRKQEEQMGEQEEQVQKQEEQVQK-QEEQMRKQEEQMREQEEQMREQEEQMLKQK 282
Query: 224 MFSKGEVRAIRYMATVVENLNKALILQHKENRSLETKYRHLQMQATKELSSQRLHFQQFM 283
++ E + + E + + Q ++ R E + R + Q K+ +Q
Sbjct: 283 EQTEQEEQTGEQEEQMREQ-EEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMW 341
Query: 284 EVLESRRDALLKQVEILGGRYHDLLLMKQAL---EFQLKKAQNATGQAEDLAEVSVDSPG 340
E +++ + KQ E +G + + ++ + E Q++K + + E+ + G
Sbjct: 342 E----QKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMG 397
Query: 341 PSERETLPRKETVMEESQQEPMKEEQL 367
+ + +KE + E+ +Q ++EQ+
Sbjct: 398 EQKEQMGEQKEQMREQEEQMGEQKEQM 424
Score = 30.4 bits (67), Expect = 7.7
Identities = 19/92 (20%), Positives = 48/92 (52%), Gaps = 3/92 (3%)
Query: 466 ESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLED 525
E QV + + +E RE Q+ +E +M +Q ++ + EQE Q + ++ + +
Sbjct: 168 EQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQ---MGEQEEQMQKQEEQMGE 224
Query: 526 LAREQQRRWVQLEKEQESPRREPEQLGEDVER 557
+ +++ Q+ +++E +++ EQ+ + E+
Sbjct: 225 QEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQ 256
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 56.6 bits (135), Expect = 1e-07
Identities = 84/391 (21%), Positives = 164/391 (41%), Gaps = 57/391 (14%)
Query: 202 QHTMNTKASEVTSMLQELLDSTMFSKGEVRAIRYMATVVENLNKALILQHKENRSLETK- 260
QH + E ++ L DS F+ +A+ +AT + ++ + KE +L +
Sbjct: 211 QHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLEL 270
Query: 261 YRHLQMQATKELSSQRLHFQQFMEVLESRRDALLKQVEILGGRYH--DLLLMKQALEFQL 318
YR+ +EL + Q+ ++++ES + + V+ L + LLL +Q L+ +
Sbjct: 271 YRNTITD--EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEA 328
Query: 319 ----KKAQNATGQAEDLAEVSV--DSPGPSERETLPRKETVMEESQQEPMKEEQLFSPLP 372
K+ Q+ + + + E + + + E + R+E ++E +++ ++E+
Sbjct: 329 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEE------ 382
Query: 373 PSPMAMIRDSGAIAAGHQPLSTMTVRSRVADVFGSKDTESLEPVLLPLVDRRFPKKWERP 432
I + + + R + + E + R+ WE+
Sbjct: 383 -----------KIREQEEKIREQEEKMRRQEEMMWEKEEKMR--------RQEEMMWEKE 423
Query: 433 VAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPW--EEEFGREMRR 490
K + QE+ + +I+ K E R+ + QEE E+E +E
Sbjct: 424 ------EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEA 477
Query: 491 QLWLEEE-------EMWQQRQKKWALLEQEH-QEKLRQWNLEDLAREQQRRWVQLEK--E 540
++W +EE ++ +Q +K W E+ H QEK+R+ E+ +EQ+ W Q EK E
Sbjct: 478 KMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIRE---EEKRQEQEEMWRQEEKIRE 534
Query: 541 QESPRREPEQLGEDVERRIFTPTSRWRDLEK 571
QE R+ E++ E E+ WR EK
Sbjct: 535 QEEIWRQKEKIHEQEEKIRKQEEKMWRQEEK 565
Score = 48.5 bits (114), Expect = 3e-05
Identities = 76/367 (20%), Positives = 151/367 (41%), Gaps = 51/367 (13%)
Query: 211 EVTSMLQELLDSTMFSKGEVRAIRYMATVVENLNKALILQHKENRSLETKYRHLQMQAT- 269
E + LQE L K E++ LN + + E L + LQ +A
Sbjct: 282 EKNAKLQEKLQLVESEKSEIQ-----------LNVKELKRKLERAKLLLPQQQLQAEADH 330
Query: 270 --KELSSQRLHFQQFMEVLESRRDALLKQVEILGGRYHDLLLMKQALEFQLKKAQNATGQ 327
KEL S Q +E E +Q E + + + ++ ++ Q +K + Q
Sbjct: 331 LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE---Q 387
Query: 328 AEDLAEVSVDSPGPSERETLPRKETVMEESQQEPMKEEQLFSPLPPSPMAMIRDSGAIAA 387
E + E + E + R+E +M E +++ ++E++ + M R +
Sbjct: 388 EEKIRE---------QEEKMRRQEEMMWEKEEKMRRQEEM---MWEKEEKMRRQEEMMWE 435
Query: 388 GHQPLSTMTVRSRVADVFGSKDTESLEPVLLPLVDRRFP---KKW--ERPVAESLGHKDK 442
+ + + + + ++ + E + ++R K W E + E K +
Sbjct: 436 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ-EEKIR 494
Query: 443 DQEDYFQKGGLQIKFHCSKQLSLESSRQVTSE---------SQEEPW-EEEFGREMRRQL 492
+QE+ + + K H +++ E RQ E QEE W ++E E ++
Sbjct: 495 EQEEKMWRQ--EEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKI 552
Query: 493 WLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKEQESPRREPEQLG 552
+EE+MW+Q +K E+ +++ + W E+ REQ+ + +EQE RE E++
Sbjct: 553 RKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEK----IREQEEKIREQEEMT 608
Query: 553 EDVERRI 559
++ E ++
Sbjct: 609 QEQEEKM 615
Score = 42.4 bits (98), Expect = 0.002
Identities = 33/138 (23%), Positives = 71/138 (51%), Gaps = 12/138 (8%)
Query: 440 KDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEM 499
K ++QE+ +++ + K H ++ + ++ + ++ +EE RE ++W +EE++
Sbjct: 531 KIREQEEIWRQ---KEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKI 587
Query: 500 WQQRQKKWALLEQE----HQEKLRQWNLEDLAREQQRRWVQLEK--EQESPRREPEQLGE 553
+Q +K + EQE QE++ Q E + ++++ Q EK EQE R E+
Sbjct: 588 REQEEK---IREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIR 644
Query: 554 DVERRIFTPTSRWRDLEK 571
+ E++I + R+ E+
Sbjct: 645 EQEKKIREQEEKIREQEE 662
Score = 42.4 bits (98), Expect = 0.002
Identities = 29/127 (22%), Positives = 65/127 (51%), Gaps = 7/127 (5%)
Query: 431 RPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWEEEFG-REMR 489
R E + +++ ++ +K G Q + C ++ ++ + +E+ E+E RE
Sbjct: 595 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQE 654
Query: 490 RQLWLEEEEMWQQRQKKWALLEQ--EHQEKLRQWNLEDLAREQQRRW---VQLEKEQESP 544
++ +EE M +Q +K W E+ E +EK+++ E + R++++ W V+L +++E
Sbjct: 655 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE-EKMRRQEEKMWEQEVRLRQQEEKM 713
Query: 545 RREPEQL 551
+ E L
Sbjct: 714 QEHQEHL 720
Score = 39.3 bits (90), Expect = 0.016
Identities = 33/142 (23%), Positives = 70/142 (49%), Gaps = 12/142 (8%)
Query: 431 RPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWE-EEFGREMR 489
R E + +++ D +K Q + ++ + + E +E+ E EE +E
Sbjct: 553 RKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQE 612
Query: 490 RQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKEQESPRREPE 549
++ +EE+M +Q +K QE +EK+R+ E+ REQ+++ +EQE RE E
Sbjct: 613 EKMGEQEEKMCEQEEKM-----QEQEEKMRR--QEEKIREQEKK----IREQEEKIREQE 661
Query: 550 QLGEDVERRIFTPTSRWRDLEK 571
++ ++ E +++ + + E+
Sbjct: 662 EMMQEQEEKMWEQEEKMCEQEE 683
Score = 38.5 bits (88), Expect = 0.028
Identities = 28/112 (25%), Positives = 57/112 (50%), Gaps = 6/112 (5%)
Query: 465 LESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLE---QEHQEKLRQW 521
+ ++T E +E+ E+E + + E+EE +++++K E +E +EK+R+
Sbjct: 601 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ 660
Query: 522 NLEDLAREQQRRWVQLEK--EQESPRREPEQLGEDVERRIFTPTSRWRDLEK 571
E + ++++ W Q EK EQE +E E+ E +++ R R E+
Sbjct: 661 E-EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 711
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 55.5 bits (132), Expect = 2e-07
Identities = 36/115 (31%), Positives = 61/115 (53%), Gaps = 20/115 (17%)
Query: 461 KQLSLESSRQVTSESQEEPWE-EEFGREMRRQLWLEEEEMWQQ----RQKKWALLEQEHQ 515
+Q L + E +E+ WE EE RE ++W +EE +W+Q R+++ + +QE +
Sbjct: 339 EQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 398
Query: 516 -----EKLRQWNLEDLAREQQRRWVQLEK--------EQESPRREPEQLGEDVER 557
E+LR+ E+ REQ++ W Q+EK EQE R+ E+ ++ ER
Sbjct: 399 MWEQDERLRE--KEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEER 451
Score = 54.7 bits (130), Expect = 4e-07
Identities = 38/136 (27%), Positives = 66/136 (48%), Gaps = 12/136 (8%)
Query: 442 KDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWEEEFGREMRRQLWLEEE---- 497
++QE+ QK + + +Q E +Q E +E+ WE+E +E ++W +EE
Sbjct: 467 REQEEKMQKQ----EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRD 522
Query: 498 --EMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKEQESPRREPEQLGEDV 555
EMW Q +K W + QE + W E+ R+Q+++ E+ E +E E+ D
Sbjct: 523 QEEMWGQEKKMWRQEKMREQED-QMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQ 581
Query: 556 ERRIFTPTSRWRDLEK 571
E ++ R R+ EK
Sbjct: 582 EEKM-REEERMREREK 596
Score = 54.3 bits (129), Expect = 5e-07
Identities = 75/347 (21%), Positives = 139/347 (40%), Gaps = 51/347 (14%)
Query: 245 KALILQHKENRSLETKYRHLQMQATKELSSQRLHFQQFMEVLESRRDALLKQVEILGGRY 304
K L Q KE R E + R KEL Q Q+ E + + + + +Q E + +
Sbjct: 321 KRLREQEKELREQEKELRE-----QKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQE 375
Query: 305 HDLLLMKQALEFQLKKAQNATGQAEDLAEVSVDSPGPSERETLPRKETVMEESQQ----- 359
L ++ + Q +K ++ Q E + E + E L KE M E ++
Sbjct: 376 ERLWEQEKQMREQEQKMRD---QEERMWE---------QDERLREKEERMREQEKMWEQV 423
Query: 360 EPMKEEQLFSPLPPSPMAMIRDSGAIAAGHQPLSTMTVRSRVADVFGSKDTESLEPVLLP 419
E M+EE+ RD + + + R + + E ++
Sbjct: 424 EKMREEKKMQEQEKKT----RDQEEKMQEEERIREREKKMREEEETMREQEEKMQ----- 474
Query: 420 LVDRRFPKKWERPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQ--- 476
++ WE+ E + +Q++ + Q K ++ E ++ + +
Sbjct: 475 ---KQEENMWEQEEKEWQQQRLPEQKEKLWE---QEKMQEQEEKIWEQEEKIRDQEEMWG 528
Query: 477 --EEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQ-----EHQEKLRQWNLEDLARE 529
++ W +E RE Q+W +EE+M Q QK W E+ + QEK + W+ E+ RE
Sbjct: 529 QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEK-KTWDQEEKMRE 587
Query: 530 QQR---RWVQLEKEQESPRREPEQLGEDVERRIFTPTSRWRDLEKAE 573
++R R ++ +E+E R + E++ E E+ W EK +
Sbjct: 588 EERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQ 634
Score = 53.5 bits (127), Expect = 8e-07
Identities = 41/177 (23%), Positives = 76/177 (42%), Gaps = 12/177 (6%)
Query: 423 RRFPKKWERPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWEE 482
R K WE+ E + + K QE + + K +++ E +++ E + +E
Sbjct: 414 REQEKMWEQ--VEKMREEKKMQEQEKKTRDQEEKMQEEERIR-EREKKMREEEETMREQE 470
Query: 483 EFGREMRRQLWLEEEEMWQQ------RQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQ 536
E ++ +W +EE+ WQQ ++K W + + QE+ + W E+ R+Q+ W Q
Sbjct: 471 EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE-KIWEQEEKIRDQEEMWGQ 529
Query: 537 LEK--EQESPRREPEQLGEDVERRIFTPTSRWRDLEKAELSLVPAPSRTQSAHQSRR 591
+K QE R + +Q+ E E+ W E+ E +T + R
Sbjct: 530 EKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMR 586
Score = 51.2 bits (121), Expect = 4e-06
Identities = 48/190 (25%), Positives = 93/190 (48%), Gaps = 15/190 (7%)
Query: 392 LSTMTVRSRVADVFGSKDTESLEPVLLPL----VDRRFPKKWERPVAESLGHKDKDQEDY 447
LS ++ R + AD + + T+ + + L L + KK + E L + ++ +
Sbjct: 185 LSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSE- 243
Query: 448 FQKGGLQIKFHCSKQLSLESSRQVTSESQEEPW-EEEFGREMRRQLWLEEEEMWQQRQKK 506
Q ++K + L Q T+ QEE W +EE RE +++ +EE+MW+Q ++
Sbjct: 244 IQLNVKELKRKLERAKFLLPQVQ-TNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEER- 301
Query: 507 WALLEQE---HQEKLRQWNLEDLAREQQRRWVQLEKE--QESPRREPEQLGEDVERRIFT 561
L EQE +++ + W E REQ++ + EKE ++ RE E+ ++ E +++
Sbjct: 302 --LREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWE 359
Query: 562 PTSRWRDLEK 571
+ R+ E+
Sbjct: 360 QEEKMREQEE 369
Score = 51.2 bits (121), Expect = 4e-06
Identities = 38/137 (27%), Positives = 67/137 (48%), Gaps = 11/137 (8%)
Query: 427 KKWERPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWEEEFGR 486
K W + E L ++ + +K Q K ++ L + E +E +EE +
Sbjct: 294 KMWRQE--ERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQ 351
Query: 487 EMRRQLWLEEEEMWQQRQKKW----ALLEQEHQEKLRQWNLEDLAREQQRRWVQLE--KE 540
E ++W +EE+M +Q +K W L EQE Q + ++ + D +++R W Q E +E
Sbjct: 352 EQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRD---QEERMWEQDERLRE 408
Query: 541 QESPRREPEQLGEDVER 557
+E RE E++ E VE+
Sbjct: 409 KEERMREQEKMWEQVEK 425
Score = 49.7 bits (117), Expect = 1e-05
Identities = 41/131 (31%), Positives = 65/131 (49%), Gaps = 24/131 (18%)
Query: 465 LESSRQVTSESQEEPW-EEEFGREMRRQLWLEEEEMWQQ----RQKKWALLEQE----HQ 515
L + + +E+ W +EE RE ++ +EE+MW+Q R+++ L EQE Q
Sbjct: 281 LREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQ 340
Query: 516 EKLRQ------------WNLEDLAREQQRR-WVQLEK--EQESPRREPEQLGEDVERRIF 560
++LR+ W E+ REQ+ + W Q E+ EQE RE EQ D E R++
Sbjct: 341 KELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMW 400
Query: 561 TPTSRWRDLEK 571
R R+ E+
Sbjct: 401 EQDERLREKEE 411
Score = 49.3 bits (116), Expect = 2e-05
Identities = 64/309 (20%), Positives = 124/309 (40%), Gaps = 36/309 (11%)
Query: 284 EVLESRRDALLKQVEILGGRYHDLLLMKQALEFQLKKAQNATGQAEDLAEVSVDSPGPSE 343
E + + D + +Q E + + + ++ +E KK Q + D E + E
Sbjct: 537 EKMREQEDQMWEQEEKMRDQEQKMWDQEERME---KKTQEQEKKTWDQEEKMREEERMRE 593
Query: 344 RETLPRKETVMEESQQEPMKEEQLFSPLPPSPMAMIRDSGAIAAGHQPLSTMTVRSRVAD 403
RE R+E M Q+E M+E++ + M + + + +
Sbjct: 594 REKKMREEEEMMREQEEKMQEQE--EKMQEQEEKMWEQEEKMQEQEEKMWEQEEK----- 646
Query: 404 VFGSKDTESLEPVLLPLVDRRFPKKWERPVAESLGHKDKDQEDYFQKGGLQIK------- 456
++ + E LP + K WE + + +E +++ ++ K
Sbjct: 647 -MWEQEEKMWEQQRLP---EQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKK 702
Query: 457 -FHCSKQLSLESSRQVTSESQEEPW----EEEFGREMRRQLWLEEEEMWQQRQKKW---- 507
+ K ES R+ + +EE +EE +E ++ +EEEMW+Q +K W
Sbjct: 703 TWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEE 762
Query: 508 ALLEQEH--QEKLRQWNLEDLAREQQRRWVQLEK---EQESPRREPEQLGEDVERRIFTP 562
+ EQ+ ++K + W E + +EQ++ W Q EK ++E R + E++ E+
Sbjct: 763 KMWEQQRLPEQKEKLWEHEKM-QEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQE 821
Query: 563 TSRWRDLEK 571
W EK
Sbjct: 822 EKMWGQEEK 830
Score = 48.5 bits (114), Expect = 3e-05
Identities = 27/115 (23%), Positives = 58/115 (50%), Gaps = 6/115 (5%)
Query: 465 LESSRQVTSESQEEPWE-EEFGREMRRQLWLEEEEMWQQRQKKWALLE-QEHQEKL---- 518
++ + E +E+ WE EE +E ++W +EE+MW+Q +K W E +EKL
Sbjct: 612 MQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHE 671
Query: 519 RQWNLEDLAREQQRRWVQLEKEQESPRREPEQLGEDVERRIFTPTSRWRDLEKAE 573
+ E + ++++ W Q + E+++ +E + ++ R + R + + + E
Sbjct: 672 KMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEE 726
Score = 41.2 bits (95), Expect = 0.004
Identities = 21/94 (22%), Positives = 45/94 (47%)
Query: 466 ESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLED 525
E ++ + ++ +EE R ++ +EE+MW Q +K W E+ ++ + W E+
Sbjct: 791 EQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEE 850
Query: 526 LAREQQRRWVQLEKEQESPRREPEQLGEDVERRI 559
E+ + + +EQE R E+ + E ++
Sbjct: 851 KMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKM 884
Score = 40.4 bits (93), Expect = 0.007
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 13/85 (15%)
Query: 476 QEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWV 535
+E+ W +E ++W +EE+MW Q +K W E++ +EK++ E+ REQ+ +
Sbjct: 821 EEKMWGQE------EKMWGQEEKMWGQEEKMWG-QEEKMEEKMQ--GQEEKMREQEEKM- 870
Query: 536 QLEKEQESPRREPEQLGEDVERRIF 560
+ QE RE E+ E +I+
Sbjct: 871 ---RGQEEKMREQEEKMRGQEEKIY 892
Score = 37.7 bits (86), Expect = 0.048
Identities = 23/86 (26%), Positives = 47/86 (54%), Gaps = 2/86 (2%)
Query: 474 ESQEEPWE-EEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLED-LAREQQ 531
+ QE+ WE EE R+ ++ +EE+M Q +K E+ ++ + W E+ + +++
Sbjct: 784 QEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEE 843
Query: 532 RRWVQLEKEQESPRREPEQLGEDVER 557
+ W Q EK +E + + E++ E E+
Sbjct: 844 KMWGQEEKMEEKMQGQEEKMREQEEK 869
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 55.5 bits (132), Expect = 2e-07
Identities = 39/130 (30%), Positives = 62/130 (47%), Gaps = 21/130 (16%)
Query: 461 KQLSLESSRQVTSESQEEPWE-EEFGREMRRQLWLEEEEMWQQ----RQKKWALLEQEHQ 515
+Q L + E +E+ WE EE RE ++W +EE +W+Q R+++ + +QE +
Sbjct: 301 EQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 360
Query: 516 -----EKLRQWNLEDLAREQQRRWVQLEKEQESP---------RREPEQLGEDVERRIFT 561
E+LR+ E+ REQ++ W Q EK QE R E E + E E+
Sbjct: 361 MWEQDERLRE--KEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ 418
Query: 562 PTSRWRDLEK 571
+ W EK
Sbjct: 419 EENMWEQEEK 428
Score = 53.1 bits (126), Expect = 1e-06
Identities = 35/99 (35%), Positives = 54/99 (54%), Gaps = 6/99 (6%)
Query: 476 QEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQ--EHQEKLRQWNLEDLAREQQRR 533
+++ W +E RE Q+W +EE+M Q QK W E+ E E+LR+ E+ REQ++
Sbjct: 472 EKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLRE--KEERMREQKKM 529
Query: 534 WVQLEK-EQESPRREPEQLGEDVERRIFTPTSRWRDLEK 571
W Q EK +E +E E+ D E ++ R R+ EK
Sbjct: 530 WQQEEKMREEKKTQEQEKKTWDQEEKM-REEERMREREK 567
Score = 51.6 bits (122), Expect = 3e-06
Identities = 34/123 (27%), Positives = 63/123 (51%), Gaps = 23/123 (18%)
Query: 474 ESQEEPWE-EEFGREMRRQLWLEEEEMWQQ----RQKKWALLEQ----EHQEKLRQ---- 520
E +++ WE EE R+ +++W +EE MW+Q R+K+ + EQ + +EK+R+
Sbjct: 483 EQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKT 542
Query: 521 -------WNLEDLAREQQR---RWVQLEKEQESPRREPEQLGEDVERRIFTPTSRWRDLE 570
W+ E+ RE++R R ++ +E+E R + E++ E E+ W E
Sbjct: 543 QEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEE 602
Query: 571 KAE 573
K +
Sbjct: 603 KMQ 605
Score = 50.4 bits (119), Expect = 7e-06
Identities = 29/120 (24%), Positives = 59/120 (49%), Gaps = 13/120 (10%)
Query: 465 LESSRQVTSESQEEPWE-EEFGREMRRQLWLEEEEMWQQRQKK---------WALLEQEH 514
++ + E +E+ WE EE +E ++W +EE+MW+Q ++ W E+
Sbjct: 583 MQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQ 642
Query: 515 QEKLRQWNLEDLAREQQRRWVQLEKE---QESPRREPEQLGEDVERRIFTPTSRWRDLEK 571
+++ + W E+ REQ+ + + E++ QE RE E+ + E ++ + R E+
Sbjct: 643 EQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEE 702
Score = 47.4 bits (111), Expect = 6e-05
Identities = 30/148 (20%), Positives = 72/148 (48%), Gaps = 6/148 (4%)
Query: 427 KKWERPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWEEEFGR 486
+K R E + +++ ++ +K Q + ++ ++ + E +E+ WE+E
Sbjct: 566 EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEED 625
Query: 487 EMRRQ---LWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKEQES 543
+M+ Q +W +EE+M +Q +K W EQE + + ++ + + + Q + ++ +++E
Sbjct: 626 KMQEQEEMMWEQEEKMQEQEEKMW---EQEEKMREQEEKMREQEEKMQGQEEKMREQEEK 682
Query: 544 PRREPEQLGEDVERRIFTPTSRWRDLEK 571
+ + E++ E E+ W EK
Sbjct: 683 MQGQEEKMREQEEKMRGQEEKMWGQEEK 710
Score = 47.0 bits (110), Expect = 8e-05
Identities = 33/138 (23%), Positives = 65/138 (47%), Gaps = 6/138 (4%)
Query: 440 KDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEM 499
++K++ QK Q + ++ + + T + +E+ EEE RE +++ EEE M
Sbjct: 517 REKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM 576
Query: 500 WQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRR-WVQLEK-----EQESPRREPEQLGE 553
+Q +K E+ +++ + W E+ +EQ+ + W Q EK E++ + + E + E
Sbjct: 577 REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWE 636
Query: 554 DVERRIFTPTSRWRDLEK 571
E+ W EK
Sbjct: 637 QEEKMQEQEEKMWEQEEK 654
Score = 45.8 bits (107), Expect = 2e-04
Identities = 74/382 (19%), Positives = 164/382 (42%), Gaps = 34/382 (8%)
Query: 206 NTKASEVTSMLQELLDSTMFSKGEVRA-IRYMATVVENLNKALILQHKENRSLETKYRHL 264
N + + + LQE L K E++ ++ + +E K L+ Q + N E +R
Sbjct: 182 NEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERA-KFLLPQVQTNTLQEEMWRQE 240
Query: 265 Q--MQATKELSSQRLHFQQFMEVLESRRDALLKQVEILGGRYHDLLLMKQAL---EFQLK 319
+ + K++ Q + E L + + +Q E + + L ++ L E +L+
Sbjct: 241 EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELR 300
Query: 320 KAQNATGQAEDLAEVSVDSPGPSERETLPRKETVMEESQQEPMKEEQLFSP---LPPSPM 376
+ + Q E + E E + ++E + E+ ++ +EE+L+ +
Sbjct: 301 EQKKLREQEEQMQE--------QEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQ 352
Query: 377 AMIRDSGAIAAGHQPLSTMTVRSRVADVFGSKDTESLEPVLLPLVDRRFPKKWE--RPVA 434
M + + L R R + ++ + E + +++ ++ E R
Sbjct: 353 KMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQE 412
Query: 435 ESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWEEEFGREMRRQLWL 494
E + ++++ + +K Q + K+ E + E +E+ WE+E + ++W
Sbjct: 413 EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKM--QEQEEKIWEQEEKIRDQEEMWG 470
Query: 495 EEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQ-QRRWVQLEK--EQESPRREPEQL 551
+E++MW+Q + + EQE Q W E+ R+Q Q+ W Q E+ EQ+ RE E+
Sbjct: 471 QEKKMWRQEKMR----EQEDQ----MWEQEEKMRDQEQKMWDQEERMWEQDERLREKEER 522
Query: 552 GEDVERRIFTPTSRWRDLEKAE 573
+ +++++ + R+ +K +
Sbjct: 523 MRE-QKKMWQQEEKMREEKKTQ 543
Score = 45.4 bits (106), Expect = 2e-04
Identities = 39/156 (25%), Positives = 74/156 (47%), Gaps = 22/156 (14%)
Query: 423 RRFPKKWERPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWEE 482
R K W++ E + + K QE + + K +++ E +++ E + +E
Sbjct: 524 REQKKMWQQE--EKMREEKKTQEQEKKTWDQEEKMREEERMR-EREKKMREEEEMMREQE 580
Query: 483 EFGREMRRQLWLEEEEMW-------QQRQKKW----ALLEQEHQEKLRQ-----WNLEDL 526
E +E ++ +EE+MW +Q +K W + EQE ++K+++ W E+
Sbjct: 581 EKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEK 640
Query: 527 AREQQRR-WVQLEK--EQESPRREPEQLGEDVERRI 559
+EQ+ + W Q EK EQE RE E+ + E ++
Sbjct: 641 MQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 676
Score = 40.0 bits (92), Expect = 0.010
Identities = 46/191 (24%), Positives = 78/191 (40%), Gaps = 12/191 (6%)
Query: 440 KDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWEEEFGRE--MRRQLWLEEE 497
K ++QE+ + +++ K E Q E E E+ G+E MR Q EE
Sbjct: 640 KMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQ----EE 695
Query: 498 EMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKEQESPRREPEQLGEDV-- 555
+M Q +K W E+ ++ + W E++ +++R Q EK QE E+ E
Sbjct: 696 KMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEPCLP 755
Query: 556 ERRIFTPTSRWRDLEKAELSL-VPAPSRTQSAHQSRRPHLPMSPSTQQPALGKQRPMSSV 614
++ S +E A +P +A + + M + Q P LG S +
Sbjct: 756 PSKVLCNMSHTGSVEPAGGEAGEGSPQDNPTAQEIMQLFCGMKNAQQCPGLGS---TSCI 812
Query: 615 EFTYRPRTRRV 625
F YR R++
Sbjct: 813 PFFYRGDKRKM 823
Score = 32.3 bits (72), Expect = 2.0
Identities = 34/135 (25%), Positives = 62/135 (45%), Gaps = 18/135 (13%)
Query: 427 KKWERPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWEEEFGR 486
K WE+ + + ++QE+ + +++ K E + E E E+ G+
Sbjct: 617 KMWEQEEEDKM----QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQ 672
Query: 487 E--MRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEK--EQE 542
E MR Q EE+M Q +K +E +EK+R E + ++++ W Q EK QE
Sbjct: 673 EEKMREQ----EEKMQGQEEKM-----REQEEKMRGQE-EKMWGQEEKMWGQEEKMWGQE 722
Query: 543 SPRREPEQLGEDVER 557
R + E++ + E+
Sbjct: 723 EMREKEERIRDQKEK 737
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 54.3 bits (129), Expect = 5e-07
Identities = 80/402 (19%), Positives = 165/402 (41%), Gaps = 59/402 (14%)
Query: 202 QHTMNTKASEVTSMLQELLDSTMFSKGEVRAIRYMATVVENLNKALILQHKENRSLETK- 260
QH + E ++ L DS F+ +A+ +AT + ++ + KE +L +
Sbjct: 150 QHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLEL 209
Query: 261 YRHLQMQATKELSSQRLHFQQFMEVLESRRDALLKQVEILGGRYH--DLLLMKQALEFQL 318
YR+ +EL + Q+ ++++ES + + V+ L + LLL +Q L+ +
Sbjct: 210 YRNTITD--EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEA 267
Query: 319 ----KKAQNATGQAEDLAEVSV--DSPGPSERETLPRKETVMEESQQEPMKEEQLFSPLP 372
K+ Q+ + + + E + + + E + R+E ++E +++ ++E+
Sbjct: 268 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEE------ 321
Query: 373 PSPMAMIRDSGAIAAGHQPLSTMTVRSRVADVFGSKDTESLEPVLLPLVDRRFPKKWE-- 430
I + + + R + + E + R+ WE
Sbjct: 322 -----------KIREQEEKIREQEEKMRRQEEMMWEKEEKMR--------RQEEMMWEKE 362
Query: 431 ---RPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEP----W-EE 482
R + E + K++ + +K Q K ++ E + E ++E W +E
Sbjct: 363 EKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 422
Query: 483 EFGREMRRQLWLEEEEMWQQRQK----KWALLEQEHQEKLRQWNLEDLAREQQRRWVQLE 538
E RE ++ +E++MW+Q +K + E++ QE+ W E+ REQ+ W Q E
Sbjct: 423 EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE 482
Query: 539 K---------EQESPRREPEQLGEDVERRIFTPTSRWRDLEK 571
K ++E R+ E++ + E+ WR EK
Sbjct: 483 KMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEK 524
Score = 49.3 bits (116), Expect = 2e-05
Identities = 30/125 (24%), Positives = 61/125 (48%), Gaps = 13/125 (10%)
Query: 456 KFHCSKQLSLESSRQVTSE---------SQEEPWEEEFGREMRRQLWLEEEEMWQQRQKK 506
K H +++ E RQ E QEE W ++ + ++ +EE++W+Q +K
Sbjct: 445 KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKM 504
Query: 507 WALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKEQESPRREPEQLGEDVERRIFTPTSRW 566
E+ +++ + W E+ REQ+ + +EQE RE E++ ++ E ++ +
Sbjct: 505 HDQEEKIREQEEKMWRQEEKIREQEEK----IREQEEKIREQEEMMQEQEEKMGEQEEKM 560
Query: 567 RDLEK 571
++ EK
Sbjct: 561 QEQEK 565
Score = 43.5 bits (101), Expect = 9e-04
Identities = 30/121 (24%), Positives = 64/121 (52%), Gaps = 11/121 (9%)
Query: 435 ESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWE-EEFGREMRRQLW 493
E +G +++ ++ + + K ++ + ++ E +E+ WE EE RE +
Sbjct: 551 EKMGEQEEKMQEQEKMRRQEEKIR-EQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQ 609
Query: 494 LEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRW---VQLEKEQESPRREPEQ 550
+EE+MW+Q +K + EQE EK+++ E + R++++ W V+L +++E + E
Sbjct: 610 EQEEKMWEQEEK---MCEQE--EKMQEQE-EKMRRQEEKMWEQEVRLRQQEEKMQEHQEH 663
Query: 551 L 551
L
Sbjct: 664 L 664
Score = 42.0 bits (97), Expect = 0.003
Identities = 30/124 (24%), Positives = 67/124 (54%), Gaps = 8/124 (6%)
Query: 440 KDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPW-EEEFGREMRRQLWLEEEE 498
+ + +E + Q+ ++ + +Q ++ + +E+ W +EE + ++ +EE+
Sbjct: 458 RQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEK 517
Query: 499 MWQQRQKKWALLE--QEHQEKLRQWNLEDLAREQQRRWVQLE---KEQESPRREPEQLGE 553
MW+Q +K E +E +EK+R+ E++ +EQ+ + + E +EQE RR+ E++ E
Sbjct: 518 MWRQEEKIREQEEKIREQEEKIRE--QEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIRE 575
Query: 554 DVER 557
E+
Sbjct: 576 QEEK 579
Score = 40.4 bits (93), Expect = 0.007
Identities = 32/136 (23%), Positives = 70/136 (51%), Gaps = 8/136 (5%)
Query: 440 KDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEM 499
K ++QE+ ++ +I+ ++ ++ + E +E+ E+E R ++ +EE++
Sbjct: 524 KIREQEEKIREQEEKIR---EQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKI 580
Query: 500 WQQRQKKWALLEQ--EHQEKLRQWNLEDLAREQQRRWVQLEK--EQESPRREPEQLGEDV 555
+Q++K E+ E +EK+R+ E + ++++ W Q EK EQE +E E+
Sbjct: 581 REQKEKIREQEEKIWEQEEKIREQE-EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 639
Query: 556 ERRIFTPTSRWRDLEK 571
E +++ R R E+
Sbjct: 640 EEKMWEQEVRLRQQEE 655
Score = 38.9 bits (89), Expect = 0.022
Identities = 26/127 (20%), Positives = 64/127 (50%), Gaps = 10/127 (7%)
Query: 431 RPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWEEEFGREMRR 490
R E + +++ ++ +K G Q + ++ ++ + ++ ++E RE
Sbjct: 533 REQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEE 592
Query: 491 QLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKEQESPRREPEQ 550
++W +EE++ +Q + + QE +EK+ W E+ EQ+ + +++++E RR+ E+
Sbjct: 593 KIWEQEEKIREQEE-----MMQEQEEKM--WEQEEKMCEQEEK---MQEQEEKMRRQEEK 642
Query: 551 LGEDVER 557
+ E R
Sbjct: 643 MWEQEVR 649
Score = 37.7 bits (86), Expect = 0.048
Identities = 31/133 (23%), Positives = 62/133 (46%), Gaps = 18/133 (13%)
Query: 456 KFHCSKQLSLESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQ 515
K H ++ E ++ + ++ +EE RE ++ E+EEM Q++++K E++ Q
Sbjct: 503 KMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKI-REQEEMMQEQEEKMGEQEEKMQ 561
Query: 516 EKLRQWNLEDLAREQQRR---------------WVQLEK--EQESPRREPEQLGEDVERR 558
E+ + E+ REQ+ + W Q EK EQE +E E+ + E +
Sbjct: 562 EQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEK 621
Query: 559 IFTPTSRWRDLEK 571
+ + ++ E+
Sbjct: 622 MCEQEEKMQEQEE 634
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 53.9 bits (128), Expect = 6e-07
Identities = 26/86 (30%), Positives = 46/86 (53%), Gaps = 1/86 (1%)
Query: 465 LESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLE 524
++ + E +E+ W +E + ++W +EE+MW+Q +K W E+ +++ + E
Sbjct: 471 IQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQE 530
Query: 525 DLAREQQ-RRWVQLEKEQESPRREPE 549
+ REQ+ R W Q EK QE R E
Sbjct: 531 EKMREQEVRLWQQEEKMQEQEVRLQE 556
Score = 47.8 bits (112), Expect = 5e-05
Identities = 32/137 (23%), Positives = 67/137 (48%), Gaps = 5/137 (3%)
Query: 440 KDKDQEDYFQKGGLQIKFHCSK----QLSLESSRQVTSESQEEPW-EEEFGREMRRQLWL 494
K ++QE+ + L+I+ K + + + E +++ W +EE RE ++
Sbjct: 305 KIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIRE 364
Query: 495 EEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKEQESPRREPEQLGED 554
+EE+MW+Q +K E+ +++ W E+ REQ+ + + QE RE ++ +
Sbjct: 365 QEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIRE 424
Query: 555 VERRIFTPTSRWRDLEK 571
E ++ + R+LE+
Sbjct: 425 QEEEMWRQEEKIRELEE 441
Score = 46.2 bits (108), Expect = 1e-04
Identities = 29/95 (30%), Positives = 57/95 (60%), Gaps = 8/95 (8%)
Query: 466 ESSRQVTSESQEEPWEEEFG-REMRRQLWLEEEEMWQQRQKKWALLE--QEHQEKLRQWN 522
E R+ + QE+ W +E RE ++ +EEEMW+Q +K L E Q+ +EKLR+
Sbjct: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLRE-- 452
Query: 523 LEDLAREQQRRWVQLEKEQESPRREPEQLGEDVER 557
+E+ +E++ + +++++E +R+ E++ E E+
Sbjct: 453 VEEKMQEEEEK---MQEQEEKIQRQEEKIQEQEEK 484
Score = 45.4 bits (106), Expect = 2e-04
Identities = 51/196 (26%), Positives = 85/196 (43%), Gaps = 18/196 (9%)
Query: 440 KDKDQEDYFQKGGLQIKFHCSK---QLSLESSRQVTSESQEEPWEEEFGREMRRQLWLEE 496
K ++QE+ Q+ +I+ K Q L + E +E+ W +E ++W +E
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQE------EKMWEQE 516
Query: 497 EEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKEQESPRREPEQLG---- 552
E+M +Q +K E+ ++++R W E+ +EQ+ R +LE+ ++ E LG
Sbjct: 517 EKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGR 576
Query: 553 EDVERRIFTPTSRWRDLEKAELSLVPAPSRTQSAHQSRRPHLPMSPSTQQPALGKQR-PM 611
E +R+ T T + + EL A S Q R + QQ A GK+ P
Sbjct: 577 ESGSQRLPTLT----PILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKEALPS 632
Query: 612 SSVEFTYRPRTRRVPT 627
S R R PT
Sbjct: 633 CSSRKLRAKRWLRWPT 648
Score = 43.9 bits (102), Expect = 7e-04
Identities = 26/98 (26%), Positives = 52/98 (53%), Gaps = 5/98 (5%)
Query: 476 QEEPWEEEFGREMRRQLWL--EEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRR 533
QEE +E+ + ++L + +EE+MW+Q +K E+ +++ + W E+ REQ+ +
Sbjct: 302 QEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEK 361
Query: 534 WVQLEKEQESPRREPEQLGEDVERRIFTPTSRWRDLEK 571
+ +++E R+ E++ E E+ WR EK
Sbjct: 362 ---IREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEK 396
Score = 43.1 bits (100), Expect = 0.001
Identities = 83/401 (20%), Positives = 164/401 (40%), Gaps = 62/401 (15%)
Query: 208 KASEVTSMLQ---ELLDSTMFSKGEVRAIRYMATVVENLNKALILQHKENRSLETKYRHL 264
+ EVT+ + LL+ T+ VR M T +E L K ++ SLE YR+
Sbjct: 161 RLGEVTAQKRPENSLLEETLHFDHAVR----MGTYIEKLTK-----ERDAPSLEL-YRNT 210
Query: 265 QMQATKELSSQRLHFQQFMEVLESRRDALLKQVEILGGRYH--DLLLMKQALEFQL---- 318
+EL + Q+ + ++ES + + V+ L + LLL +Q L+ +
Sbjct: 211 ITD--EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLG 268
Query: 319 KKAQNATGQAEDLAEVSV--DSPGPSERETLPRKETVMEESQQEPMKEEQLFSPLPPSPM 376
K+ Q+ + + + E + + + E + R+E ++E Q+E M E++L +
Sbjct: 269 KELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQE-QEEKMCEQEL--KIREQEE 325
Query: 377 AMIRDSGAIAAGHQPLSTMTVRSRVADVFGSKDTESLEPVLLPLVDRRFPKKW--ERPVA 434
M R + + + + + + E + + K W E +
Sbjct: 326 KMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIR--------EQEEKMWRQEEKIR 377
Query: 435 ESLGHKDKDQEDYFQKGGLQIKFHCSK--------QLSLESSRQVTSESQEEPW------ 480
E K ++QE+ + +I+ K + + + E +EE W
Sbjct: 378 EQ-DEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKI 436
Query: 481 ---------EEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQ 531
+EE RE+ ++ EEE+M +Q +K E+ +++ + W E L ++++
Sbjct: 437 RELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEE 496
Query: 532 RRWVQLEK--EQESPRREPEQLGEDVERRIFTPTSRWRDLE 570
+ W Q EK QE E E+ ++ E ++ + R+ E
Sbjct: 497 KIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQE 537
Score = 42.7 bits (99), Expect = 0.001
Identities = 106/573 (18%), Positives = 236/573 (41%), Gaps = 56/573 (9%)
Query: 23 EAAQLTRAQEDISTQLSDILDNVNCVINRFQEELGYDLKENAKSQQRDPKGKKRFILLEK 82
E A ++ S LSD +++ IN+ +++ K + K +++ +K F L E
Sbjct: 10 ERANSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIADEKFFQLSEM 69
Query: 83 IASFSKDAMMKEKHLYDILRWLGDWGDTLTYEIGPRKSEEEAAALDEWIEVTEKVLPLSL 142
+A ++ + RW D D L ++ +E + + E + +
Sbjct: 70 ------EAYLENRKRRGTKRW--DEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGV 121
Query: 143 IATKRGIESLTALCSTLIEGQKKRSQVSKR--TFWQGWQGRSPQTSPSHPQPLSPEQMLQ 200
K+ + + + E +++ ++ + W T+ P+ E+ L
Sbjct: 122 SHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLH 181
Query: 201 DQHTMN--------TKASEVTSMLQELLDSTMFS---KGEVRAIRYMATVVENLNKALIL 249
H + TK + S+ EL +T+ K + ++ +VE+ + L
Sbjct: 182 FDHAVRMGTYIEKLTKERDAPSL--ELYRNTITDEELKEKNAELQEKLRLVESEKSEIQL 239
Query: 250 QHKENRSLETKYRHLQMQATKELSSQRLHFQQFMEVLESRRDALLKQVEILGGRYHDLLL 309
K+ + + + L Q ++ + RL + ++ + ++ A +++ E+ LL
Sbjct: 240 NVKDLKRKLERAQLLLPQQQLQVEADRLGKE--LQSVSAKLQAQVEENELWN------LL 291
Query: 310 MKQALEFQLKKAQNATGQAEDLAEVSVDSPGPSERETLPRKETVMEESQQEPMKEEQLFS 369
+Q E ++ + Q E + E + + E + R+E M E Q+E ++E++
Sbjct: 292 NQQQEEKMWRQEEKIQEQEEKMCEQELKIR--EQEEKMWRQEEKMHE-QEEKIREQE--D 346
Query: 370 PLPPSPMAMIRDSGAIAAGHQPLSTMTVRSRVADVFGSKDTESL---EPVLLPLVDRRFP 426
+ + I + + + R D + E + E + ++R
Sbjct: 347 KMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQE 406
Query: 427 KKW--ERPVAESLGHKDKDQEDYFQKGGLQIK-FHCSKQLSLESSRQVTSESQEEPWEEE 483
K W E+ + E K ++QE+ + +I+ Q E R+V + QEE EE
Sbjct: 407 KMWRQEKKMREQ-DEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEE---EE 462
Query: 484 FGREMRRQLWLEEEEMWQQRQKKWA---LLEQEH---QEKLRQWNLEDLAREQQRRWVQL 537
+E ++ +EE++ +Q +K W LL+QE +++ + W E+ EQ+ + +
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK---M 519
Query: 538 EKEQESPRREPEQLGEDVERRIFTPTSRWRDLE 570
++++E +R+ E++ E E R++ + ++ E
Sbjct: 520 QEQEEKMQRQEEKMREQ-EVRLWQQEEKMQEQE 551
Score = 39.3 bits (90), Expect = 0.016
Identities = 25/114 (21%), Positives = 55/114 (48%), Gaps = 10/114 (8%)
Query: 461 KQLSLESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQE---HQEK 517
K+L S++ + E W ++ ++W +EE++ +Q +K + EQE +++
Sbjct: 269 KELQSVSAKLQAQVEENELWNL-LNQQQEEKMWRQEEKIQEQEEK---MCEQELKIREQE 324
Query: 518 LRQWNLEDLAREQQRRWVQLEKEQESPRREPEQLGEDVERRIFTPTSRWRDLEK 571
+ W E+ EQ+ + + ++++ R+ E++ E E+ WR EK
Sbjct: 325 EKMWRQEEKMHEQEEK---IREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEK 375
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 53.9 bits (128), Expect = 6e-07
Identities = 26/86 (30%), Positives = 46/86 (53%), Gaps = 1/86 (1%)
Query: 465 LESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLE 524
++ + E +E+ W +E + ++W +EE+MW+Q +K W E+ +++ + E
Sbjct: 471 IQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQE 530
Query: 525 DLAREQQ-RRWVQLEKEQESPRREPE 549
+ REQ+ R W Q EK QE R E
Sbjct: 531 EKMREQEVRLWQQEEKMQEQEVRLQE 556
Score = 47.8 bits (112), Expect = 5e-05
Identities = 32/137 (23%), Positives = 67/137 (48%), Gaps = 5/137 (3%)
Query: 440 KDKDQEDYFQKGGLQIKFHCSK----QLSLESSRQVTSESQEEPW-EEEFGREMRRQLWL 494
K ++QE+ + L+I+ K + + + E +++ W +EE RE ++
Sbjct: 305 KIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIRE 364
Query: 495 EEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKEQESPRREPEQLGED 554
+EE+MW+Q +K E+ +++ W E+ REQ+ + + QE RE ++ +
Sbjct: 365 QEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIRE 424
Query: 555 VERRIFTPTSRWRDLEK 571
E ++ + R+LE+
Sbjct: 425 QEEEMWRQEEKIRELEE 441
Score = 46.2 bits (108), Expect = 1e-04
Identities = 29/95 (30%), Positives = 57/95 (60%), Gaps = 8/95 (8%)
Query: 466 ESSRQVTSESQEEPWEEEFG-REMRRQLWLEEEEMWQQRQKKWALLE--QEHQEKLRQWN 522
E R+ + QE+ W +E RE ++ +EEEMW+Q +K L E Q+ +EKLR+
Sbjct: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLRE-- 452
Query: 523 LEDLAREQQRRWVQLEKEQESPRREPEQLGEDVER 557
+E+ +E++ + +++++E +R+ E++ E E+
Sbjct: 453 VEEKMQEEEEK---MQEQEEKIQRQEEKIQEQEEK 484
Score = 45.4 bits (106), Expect = 2e-04
Identities = 51/196 (26%), Positives = 85/196 (43%), Gaps = 18/196 (9%)
Query: 440 KDKDQEDYFQKGGLQIKFHCSK---QLSLESSRQVTSESQEEPWEEEFGREMRRQLWLEE 496
K ++QE+ Q+ +I+ K Q L + E +E+ W +E ++W +E
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQE------EKMWEQE 516
Query: 497 EEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKEQESPRREPEQLG---- 552
E+M +Q +K E+ ++++R W E+ +EQ+ R +LE+ ++ E LG
Sbjct: 517 EKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGR 576
Query: 553 EDVERRIFTPTSRWRDLEKAELSLVPAPSRTQSAHQSRRPHLPMSPSTQQPALGKQR-PM 611
E +R+ T T + + EL A S Q R + QQ A GK+ P
Sbjct: 577 ESGSQRLPTLT----PILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKEALPS 632
Query: 612 SSVEFTYRPRTRRVPT 627
S R R PT
Sbjct: 633 CSSRKLRAKRWLRWPT 648
Score = 43.9 bits (102), Expect = 7e-04
Identities = 26/98 (26%), Positives = 52/98 (53%), Gaps = 5/98 (5%)
Query: 476 QEEPWEEEFGREMRRQLWL--EEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRR 533
QEE +E+ + ++L + +EE+MW+Q +K E+ +++ + W E+ REQ+ +
Sbjct: 302 QEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEK 361
Query: 534 WVQLEKEQESPRREPEQLGEDVERRIFTPTSRWRDLEK 571
+ +++E R+ E++ E E+ WR EK
Sbjct: 362 ---IREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEK 396
Score = 43.1 bits (100), Expect = 0.001
Identities = 106/571 (18%), Positives = 237/571 (41%), Gaps = 52/571 (9%)
Query: 23 EAAQLTRAQEDISTQLSDILDNVNCVINRFQEELGYDLKENAKSQQRDPKGKKRFILLEK 82
E A ++ S LSD +++ IN+ +++ K + K +++ +K F L E
Sbjct: 10 ERANSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIADEKFFQLSEM 69
Query: 83 IASFSKDAMMKEKHLYDILRWLGDWGDTLTYEIGPRKSEEEAAALDEWIEVTEKVLPLSL 142
+A ++ + RW D D L ++ +E + + E + +
Sbjct: 70 ------EAYLENRKRRGTKRW--DEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGV 121
Query: 143 IATKRGIESLTALCSTLIEGQKKRSQVSKR--TFWQGWQGRSPQTSPSHPQPLSPEQMLQ 200
K+ + + + E +++ ++ + W T+ P+ E+ L
Sbjct: 122 SHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLH 181
Query: 201 DQHT--MNTKASEVT----SMLQELLDSTMFS---KGEVRAIRYMATVVENLNKALILQH 251
H M T ++T ++ EL +T+ K + ++ +VE+ + L
Sbjct: 182 FDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNV 241
Query: 252 KENRSLETKYRHLQMQATKELSSQRLHFQQFMEVLESRRDALLKQVEILGGRYHDLLLMK 311
K+ + + + L Q ++ + RL + ++ + ++ A +++ E+ LL +
Sbjct: 242 KDLKRKLERAQLLLPQQQLQVEADRLGKE--LQSVSAKLQAQVEENELWN------LLNQ 293
Query: 312 QALEFQLKKAQNATGQAEDLAEVSVDSPGPSERETLPRKETVMEESQQEPMKEEQLFSPL 371
Q E ++ + Q E + E + + E + R+E M E Q+E ++E++ +
Sbjct: 294 QQEEKMWRQEEKIQEQEEKMCEQELKIR--EQEEKMWRQEEKMHE-QEEKIREQE--DKM 348
Query: 372 PPSPMAMIRDSGAIAAGHQPLSTMTVRSRVADVFGSKDTESL---EPVLLPLVDRRFPKK 428
+ I + + + R D + E + E + ++R K
Sbjct: 349 WRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKM 408
Query: 429 W--ERPVAESLGHKDKDQEDYFQKGGLQIK-FHCSKQLSLESSRQVTSESQEEPWEEEFG 485
W E+ + E K ++QE+ + +I+ Q E R+V + QEE EE
Sbjct: 409 WRQEKKMREQ-DEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEE---EEKM 464
Query: 486 REMRRQLWLEEEEMWQQRQKKWA---LLEQEH---QEKLRQWNLEDLAREQQRRWVQLEK 539
+E ++ +EE++ +Q +K W LL+QE +++ + W E+ EQ+ + +++
Sbjct: 465 QEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK---MQE 521
Query: 540 EQESPRREPEQLGEDVERRIFTPTSRWRDLE 570
++E +R+ E++ E E R++ + ++ E
Sbjct: 522 QEEKMQRQEEKMREQ-EVRLWQQEEKMQEQE 551
Score = 39.3 bits (90), Expect = 0.016
Identities = 25/114 (21%), Positives = 55/114 (48%), Gaps = 10/114 (8%)
Query: 461 KQLSLESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQE---HQEK 517
K+L S++ + E W ++ ++W +EE++ +Q +K + EQE +++
Sbjct: 269 KELQSVSAKLQAQVEENELWNL-LNQQQEEKMWRQEEKIQEQEEK---MCEQELKIREQE 324
Query: 518 LRQWNLEDLAREQQRRWVQLEKEQESPRREPEQLGEDVERRIFTPTSRWRDLEK 571
+ W E+ EQ+ + + ++++ R+ E++ E E+ WR EK
Sbjct: 325 EKMWRQEEKMHEQEEK---IREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEK 375
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 53.1 bits (126), Expect = 1e-06
Identities = 31/96 (32%), Positives = 53/96 (55%), Gaps = 14/96 (14%)
Query: 476 QEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLE---------QEHQEKLRQWNLEDL 526
QE+ WEEE +E ++W +EE++ +Q +K W E QE +EK+ W E+
Sbjct: 556 QEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKM--WKQEEK 613
Query: 527 AREQQRRWVQLE---KEQESPRREPEQLGEDVERRI 559
REQ+ + + E +EQE RE E++ ++ E ++
Sbjct: 614 IREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKM 649
Score = 52.8 bits (125), Expect = 1e-06
Identities = 34/101 (33%), Positives = 54/101 (53%), Gaps = 8/101 (7%)
Query: 476 QEEPWEEEFGREMRRQ---LWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQR 532
+E WE+E +MRRQ +W +EE+M +Q + W E+ +++ W E+ RE +
Sbjct: 341 EEMMWEKE--EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE 398
Query: 533 RWVQLEK--EQESPRREPEQLGEDVERRIFTPTSRWRDLEK 571
+ + EK EQE R+E E++ E E+R WR EK
Sbjct: 399 KMHEQEKIREQEEKRQEEEKIREQ-EKRQEQEAKMWRQEEK 438
Score = 52.0 bits (123), Expect = 2e-06
Identities = 85/397 (21%), Positives = 167/397 (42%), Gaps = 55/397 (13%)
Query: 202 QHTMNTKASEVTSMLQELLDSTMFSKGEVRAIRYMATVVENLNKALILQHKENRSLETK- 260
QH + E ++ L DS F+ +A+ +AT + ++ + KE +L +
Sbjct: 150 QHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLEL 209
Query: 261 YRHLQMQATKELSSQRLHFQQFMEVLESRRDALLKQVEILGGRYH--DLLLMKQALEFQL 318
YR+ +EL + Q+ ++++ES + + V+ L + LLL +Q L+ +
Sbjct: 210 YRNTITD--EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEA 267
Query: 319 ----KKAQNATGQAEDLAEVSV--DSPGPSERETLPRKETVMEE------SQQEPMKEEQ 366
K+ Q+ + + + E + + + E + R+E ++E Q+E ++E++
Sbjct: 268 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 327
Query: 367 LFSPLPPSPMAMIRDSGAIAAGHQPLSTMTVRSRVADVFGSKDTESLEPVLLPLVDRRFP 426
+ M R + + + R ++ K+ + + R+
Sbjct: 328 --EKIREQEEKMRRQEEMMWEKEEKMR------RQEEMMWEKEEK---------MRRQEE 370
Query: 427 KKWE-----RPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEP-- 479
WE R E + K++ + +K Q K ++ E + E ++E
Sbjct: 371 MMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEA 430
Query: 480 --W-EEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQ 536
W +EE RE ++ +E++MW+Q +K QEK+R+ E+ +EQ+ W Q
Sbjct: 431 KMWRQEEKIREQEEKIREQEKKMWRQEEK------IHEQEKIRE---EEKRQEQEEMWRQ 481
Query: 537 LEK--EQESPRREPEQLGEDVERRIFTPTSRWRDLEK 571
EK EQE R+ E++ E E+ WR EK
Sbjct: 482 EEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEK 518
Score = 49.7 bits (117), Expect = 1e-05
Identities = 31/126 (24%), Positives = 61/126 (48%), Gaps = 10/126 (7%)
Query: 456 KFHCSKQLSLESSRQVTSE---------SQEEPW-EEEFGREMRRQLWLEEEEMWQQRQK 505
K H +++ E RQ E QEE W ++E E ++ +EE++W+Q +K
Sbjct: 459 KIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEK 518
Query: 506 KWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKEQESPRREPEQLGEDVERRIFTPTSR 565
E+ +++ + W E+ REQ+ W + EK E + E+ ++ E +++ +
Sbjct: 519 IREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEK 578
Query: 566 WRDLEK 571
R+ E+
Sbjct: 579 IREQEE 584
Score = 49.7 bits (117), Expect = 1e-05
Identities = 32/99 (32%), Positives = 53/99 (53%), Gaps = 4/99 (4%)
Query: 476 QEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQ-QRRW 534
QEE W EE + ++W EEE+ +Q K W E+ +++ + W E+ REQ ++R
Sbjct: 543 QEEMWREEEKMHEQEKIW-EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQ 601
Query: 535 VQLEK--EQESPRREPEQLGEDVERRIFTPTSRWRDLEK 571
Q EK +QE RE E+ ++ E +I + R+ E+
Sbjct: 602 EQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEE 640
Score = 48.5 bits (114), Expect = 3e-05
Identities = 35/147 (23%), Positives = 72/147 (48%), Gaps = 19/147 (12%)
Query: 440 KDKDQEDYFQKGGLQIKFHCSKQL-----SLESSRQVTSESQEEPW-EEEFGREMRRQLW 493
K ++QE+ +++ + K H +++ + + + +E+ W +EE RE ++
Sbjct: 471 KRQEQEEMWRQ---EEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIR 527
Query: 494 LEEEEMWQQRQK------KWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEK---EQESP 544
+EE+MW+Q +K W E+ H+++ + W E ++ + W Q EK ++E
Sbjct: 528 EQEEKMWRQEEKIREQEEMWREEEKMHEQE-KIWEEEKRQEQEDKMWRQEEKIREQEEKV 586
Query: 545 RREPEQLGEDVERRIFTPTSRWRDLEK 571
R+ E++ E E+R W+ EK
Sbjct: 587 WRQEEKIREQEEKRQEQEEKMWKQEEK 613
Score = 48.1 bits (113), Expect = 4e-05
Identities = 36/124 (29%), Positives = 59/124 (47%), Gaps = 21/124 (16%)
Query: 469 RQVTSESQEEPWEEEFGREMRRQLWLEEE------EMWQQRQKKWALLEQEHQEKLRQWN 522
RQ ++E EE R+ + ++W +EE E+W+Q++K E+ +++ + W
Sbjct: 455 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWR 514
Query: 523 LEDLAREQQRR--------WVQLEK--EQESPRREPEQLGE-----DVERRIFTPTSRWR 567
E+ REQ+ + W Q EK EQE RE E++ E + E+R WR
Sbjct: 515 QEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWR 574
Query: 568 DLEK 571
EK
Sbjct: 575 QEEK 578
Score = 43.5 bits (101), Expect = 9e-04
Identities = 35/142 (24%), Positives = 70/142 (49%), Gaps = 19/142 (13%)
Query: 440 KDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWE--------EEFGREMRRQ 491
K ++QE+ Q+ +I+ ++ + ++T E +E+ E EE +E
Sbjct: 613 KIREQEEKIQEQEEKIR---EQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEET 669
Query: 492 LWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEK--EQESPRREPE 549
+W +EE++ +Q +K +E +EK+R+ E + ++++ W Q EK EQE +E E
Sbjct: 670 MWRQEEKIREQEKK-----IREQEEKIREQE-EMMQEQEEKMWEQEEKMCEQEEKMQEQE 723
Query: 550 QLGEDVERRIFTPTSRWRDLEK 571
+ E +++ R R E+
Sbjct: 724 EKMRRQEEKMWEQEVRLRQQEE 745
Score = 41.2 bits (95), Expect = 0.004
Identities = 36/151 (23%), Positives = 71/151 (47%), Gaps = 32/151 (21%)
Query: 440 KDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTS-----------ESQEEPW-------- 480
K ++QE+ +++ + K H +++ E RQ E +E+ W
Sbjct: 539 KIREQEEMWRE---EEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIRE 595
Query: 481 EEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKE 540
+EE +E ++W +EE++ +Q +K QE +EK+R+ E+ REQ+ +++
Sbjct: 596 QEEKRQEQEEKMWKQEEKIREQEEK-----IQEQEEKIRE--QEEKIREQEE---MTQEQ 645
Query: 541 QESPRREPEQLGEDVERRIFTPTSRWRDLEK 571
+E + E++ E E+ + WR EK
Sbjct: 646 EEKMGEQEEKMCEQEEKMQEQEETMWRQEEK 676
Score = 38.1 bits (87), Expect = 0.037
Identities = 31/128 (24%), Positives = 62/128 (48%), Gaps = 19/128 (14%)
Query: 431 RPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWE--------E 482
R E + +++ ++ +K G Q + C ++ ++ + +E+ E E
Sbjct: 629 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQE 688
Query: 483 EFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKEQE 542
E RE + +EE+MW+Q +K + EQE EK+++ E + R++++ W EQE
Sbjct: 689 EKIREQEEMMQEQEEKMWEQEEK---MCEQE--EKMQEQE-EKMRRQEEKMW-----EQE 737
Query: 543 SPRREPEQ 550
R+ E+
Sbjct: 738 VRLRQQEE 745
Score = 37.4 bits (85), Expect = 0.063
Identities = 15/68 (22%), Positives = 37/68 (54%)
Query: 466 ESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLED 525
E +++ + ++ +EE +E ++W +EE+M +Q +K E+ +++ + W E
Sbjct: 679 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 738
Query: 526 LAREQQRR 533
R+Q+ +
Sbjct: 739 RLRQQEEK 746
Score = 34.7 bits (78), Expect = 0.41
Identities = 36/145 (24%), Positives = 68/145 (46%), Gaps = 20/145 (13%)
Query: 427 KKWERPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWEEEFGR 486
K WE + K QE+ ++ ++ K E RQ E +E+ W++E
Sbjct: 558 KIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQ---EQEEKMWKQE--E 612
Query: 487 EMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKEQESPRR 546
++R Q EE++ +Q +K +E +EK+R+ E++ +EQ+ + EQE
Sbjct: 613 KIREQ----EEKIQEQEEK-----IREQEEKIRE--QEEMTQEQEEKM----GEQEEKMC 657
Query: 547 EPEQLGEDVERRIFTPTSRWRDLEK 571
E E+ ++ E ++ + R+ EK
Sbjct: 658 EQEEKMQEQEETMWRQEEKIREQEK 682
>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
Length = 238
Score = 53.1 bits (126), Expect = 1e-06
Identities = 32/121 (26%), Positives = 60/121 (49%), Gaps = 18/121 (14%)
Query: 465 LESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEMWQQRQKKW----ALLEQEH--QEKL 518
++ + E +E+ WE+E +M+ Q EE+MW+Q +K W + EQ+ ++K
Sbjct: 28 MQEQEEKMREQEEKMWEQE--EKMQEQ----EEKMWEQEEKMWEQEEKMWEQQRLPEQKE 81
Query: 519 RQWNLEDLARE------QQRRWVQLEKEQESPRREPEQLGEDVERRIFTPTSRWRDLEKA 572
+ W ++ RE +Q+ W Q+EK +E + + E++ E E+ W EK
Sbjct: 82 KMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKM 141
Query: 573 E 573
+
Sbjct: 142 Q 142
Score = 45.4 bits (106), Expect = 2e-04
Identities = 27/108 (25%), Positives = 54/108 (50%)
Query: 466 ESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLED 525
E +++ E + +EE +E ++ +EE+MW+Q +K E+ +++ + W E+
Sbjct: 9 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 68
Query: 526 LAREQQRRWVQLEKEQESPRREPEQLGEDVERRIFTPTSRWRDLEKAE 573
EQQR Q EK E R E+ E++++ + R+ +K +
Sbjct: 69 KMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQ 116
Score = 42.7 bits (99), Expect = 0.001
Identities = 30/94 (31%), Positives = 51/94 (54%), Gaps = 4/94 (4%)
Query: 481 EEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRR-WVQLEK 539
EEE RE +++ EEE M +Q +K E+ +++ + W E+ +EQ+ + W Q EK
Sbjct: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
Query: 540 --EQESPRREPEQLGEDVERRIFTPTSRWRDLEK 571
EQE E ++L E E +++ R R+ E+
Sbjct: 63 MWEQEEKMWEQQRLPEQKE-KMWEQDERLREKEE 95
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 52.8 bits (125), Expect = 1e-06
Identities = 96/412 (23%), Positives = 172/412 (41%), Gaps = 52/412 (12%)
Query: 163 QKKRSQVSKRTFWQGWQGRSPQTSPSHPQPLSPEQMLQDQHTMNTKASEVTSMLQELLDS 222
++++ + +R F WQ ++ + S Q LS L++Q +A E Q L
Sbjct: 756 RQQQEEEQRRDFT--WQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPE 813
Query: 223 TMFSKGEVRAIRYMATVVENLNKALILQHKEN-RSLETKYRHLQMQATKELSSQRLHFQQ 281
+ R R ++ L + LQ +E + L+ + LQ + S ++ Q+
Sbjct: 814 EEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQK 873
Query: 282 FMEVLESRRDALLKQVEILGGRYHDLLLMKQALEFQLKKAQNATGQAED-LAEVSVDSPG 340
+ LE R R L K AL+ QL+K Q + E+ L +
Sbjct: 874 WRWQLEEERK-----------RRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRR 922
Query: 341 PSERETLPRKETVMEESQQEPMKEEQLFSPLPPSPMAMIRDSGAIAAGHQPLSTMTVRSR 400
E+E R+E +++ +++ ++EE+ +D Q L + R
Sbjct: 923 RQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRR 982
Query: 401 VADVFGS-KDTESL----EPVLLPLVDRRFPKKWERPVAESLGHKDKDQEDYFQKGGLQI 455
+ ++ E L E +L ++R ++WER + KD+ Q++ Q +
Sbjct: 983 RQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRK----KDELQQEEEQL----L 1034
Query: 456 KFHCSKQLSLESSRQVTSESQEEPWEEEF---GREMRRQLWLE-----EEEMWQQRQKKW 507
+ K+ E RQ E + + EE+ RE RR+ LE EEE+ Q+ ++
Sbjct: 1035 REEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQ-- 1092
Query: 508 ALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKEQESPRREPEQ-LGEDVERR 558
LL +E +++ RQ RE+Q R E+E ++E EQ L E+ E+R
Sbjct: 1093 -LLREEPEKRRRQ------ERERQCR------EEEELQQEEEQLLREEREKR 1131
Score = 49.7 bits (117), Expect = 1e-05
Identities = 111/580 (19%), Positives = 219/580 (37%), Gaps = 68/580 (11%)
Query: 118 RKSEEEAAALDEWIEVTEKVLPLSLIATKRGIESLTALCSTLIEGQKKRSQVSKRTFWQG 177
+K +E+ L E E +EK L +R E L E +++R++ + Q
Sbjct: 139 QKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQL---QS 195
Query: 178 WQGRSPQTSPSHPQPLSPEQMLQDQHTMNTKASEVTSMLQELLDSTMFSKGEVRAIRYMA 237
+G + P Q L ++L+ + K E + +F + E + R
Sbjct: 196 CKGHETEEFPDEEQ-LRRRELLE----LRRKGREEKQQQRRERQDRVFQEEEEKEWRKRE 250
Query: 238 TVVENLNKALILQHKEN-RSLETKYRHLQMQATKELSSQRLHFQQFMEVLESRRDALLKQ 296
TV+ + L + + R L+ + L+ +EL +R +Q + L + KQ
Sbjct: 251 TVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQ 310
Query: 297 VEILGGRYHDLLLMKQALEFQLKKAQNATGQAEDLAEVSVDSPGPSERETLPRKETVMEE 356
E ++ + + ++ Q Q E+ E + RE R+E +
Sbjct: 311 EE-----------ERREQQEERREQQERREQQEERREQQL------RREQEERREQQLRR 353
Query: 357 SQQEPMKEEQLFSPLPPSPMAMIRDSGAIAAGHQPLSTMTVRSRVADVFGSKDTESLEPV 416
Q+E +E+QL R Q L R + + + +
Sbjct: 354 EQEEERREQQL------------RREQEEERREQQLRREQQLRREQQLRREQQLRREQQL 401
Query: 417 LLPLVDRRFP--KKWERPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSE 474
RR ++ ++ E +++++E + QK + + K+ E + E
Sbjct: 402 RREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKRE 461
Query: 475 SQEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRW 534
+ E E+E ++QL ++EE +R+++W LE+E + + ++ + L REQ+ R
Sbjct: 462 EETERHEQE---RRKQQLKRDQEE---ERRERWLKLEEEERREQQERREQQLRREQEERR 515
Query: 535 VQLEKEQESPRREPEQLGEDVERRIFTPTSRWRDLEKAELSLVPAPSRTQSAHQSRRPHL 594
Q K QE R ++L + + R R+ E+ L+ + + R L
Sbjct: 516 EQRLKRQEEEERLQQRLRSEQQLR--------REQEERREQLLKREEEKRLEQERREQRL 567
Query: 595 PMSPSTQQPALGKQRPMSSVEFTYRPRTRRVPTKPKKSASFPVTGTSIRRLTWPSLQISP 654
++ L K+ + R + R+ + K+ + RL +
Sbjct: 568 KREQEERRDQLLKREEERRQQRLKREQEERLEQRLKRE--------EVERLEQEERR--- 616
Query: 655 ANIKKKVYHMDMEAQRKNLQLLSEESELRLPHYLRSKALE 694
++++ + E +R+ L SEE E R LR + E
Sbjct: 617 ---EQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQE 653
Score = 49.7 bits (117), Expect = 1e-05
Identities = 109/546 (19%), Positives = 214/546 (39%), Gaps = 71/546 (13%)
Query: 53 QEELGYDLKENAKSQQRDPKGKKRFILLEKIASFSKDAMMKEKHLYDILRWLGDWGDTLT 112
+EE D +++++ +G++R + + + E+ R+L + +
Sbjct: 760 EEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQ 819
Query: 113 YEIGPRKSEEEAAALDEWIEVTEKVLPLSLIATKRGIESLTALCSTLIEGQKKRSQVSKR 172
R+ E+E L+E ++ + L + G++ + +++RSQ +R
Sbjct: 820 RRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQE---------DQERRRSQEQRR 870
Query: 173 TF---WQGWQGRSPQTSPSHPQPLSPEQMLQDQHTMNTKASEVTSMLQELLDSTMFSKGE 229
WQ + R + + +P EQ+ ++Q + + E LQ + +
Sbjct: 871 DQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEE----LQREEREKRRRQEQ 926
Query: 230 VRAIRYMATVVENLNKALILQHKENRSLETKYRHLQMQATKELSSQRLHFQQFMEVLESR 289
R R + + + L+ + +E R + + R + + ++L ++ +
Sbjct: 927 ERQYREEEQLQQE-EEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQE 985
Query: 290 RDALLKQVEILGGRYHDLLL------MKQALEFQLKKAQNATGQAEDLAEVSVDSPGPSE 343
R+ ++ E L LL +Q E Q +K + E L + E
Sbjct: 986 REKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQE 1045
Query: 344 RETLPRKETVMEESQQEPMKEEQLFSPLPPSPMAMIRDSGAIAAGHQPLSTMTVRSRVAD 403
RE R+E EE QQE EEQL + T +
Sbjct: 1046 RERQYREE---EELQQE---EEQLLG--------------------EERETRRRQELERQ 1079
Query: 404 VFGSKDTESLEPVLLPLVDRRFPKKWERPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQL 463
++ + E LL R P+K R E + +++E+ Q+ ++ K+
Sbjct: 1080 YRKEEELQQEEEQLL----REEPEKRRRQERE---RQCREEEELQQEEEQLLREEREKRR 1132
Query: 464 SLESSRQVTSESQEEPWEEEFGRE---MRRQLWLE----EEEMWQQRQKKWALLEQE--H 514
E RQ E + + EE+ RE RR+ LE EEE QQ +++ EQE
Sbjct: 1133 RQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRR 1192
Query: 515 QEKLRQWNLEDLAREQQRRWVQLEKEQESPRR---EPEQLGEDVERRIF---TPTSRWRD 568
QE+ RQ+ E+ + Q+R+ +++Q S + EPE+ + +++ ++R
Sbjct: 1193 QERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQ 1252
Query: 569 LEKAEL 574
LE ++L
Sbjct: 1253 LEDSQL 1258
Score = 45.8 bits (107), Expect = 2e-04
Identities = 148/669 (22%), Positives = 250/669 (37%), Gaps = 119/669 (17%)
Query: 161 EGQKKRSQVSKRTFWQGWQGRSPQTSPSHPQPLSPEQMLQDQHTMNTKASEVTSMLQELL 220
E +++R Q KR Q + R Q S Q L EQ +++ K E + QE
Sbjct: 510 EQEERREQRLKR---QEEEERLQQRLRSEQQ-LRREQ--EERREQLLKREEEKRLEQERR 563
Query: 221 DSTMFSKGEVRAIRYMATVVENLNKALILQHKENRSLETKYRHLQMQATKELSSQRLHFQ 280
+ + + E R + + E + L + +E K ++ +E QRL +
Sbjct: 564 EQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKRE 623
Query: 281 QFMEVLESRRDALLKQVEILGGRYHDLLLMKQALEFQLKKAQNATGQAEDLAEVSVDSPG 340
E E RR LLK E R L +Q Q K + + E +
Sbjct: 624 ---EPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLK------- 673
Query: 341 PSERETLPRKETVMEESQQEPMKEEQLFSPLPPSPMAMIRDSGAIAAGHQPLSTMTVRSR 400
E E R++ + EE Q++ E++ S +P + ++ A + V SR
Sbjct: 674 -REHEEERREQELAEEEQEQA--RERIKSRIPKWQWQLESEADARQS--------KVYSR 722
Query: 401 VADVFGSKDTESLEPVLLPLVDRRFPKKWERPVAESLGHKDKDQE----DYFQKGGLQIK 456
G + + E R +W+ E H+ + +E D+ + + K
Sbjct: 723 PRKQEGQRRRQEQEEKRRR---RESELQWQE---EERAHRQQQEEEQRRDFTWQWQAEEK 776
Query: 457 FHCSKQ-------LSLESSRQVTSESQEE------PWEEEFG------REMRRQL-WLEE 496
+Q L + RQ+ +E +++ P EEE RE ++L +LEE
Sbjct: 777 SERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEE 836
Query: 497 EEMWQQRQKKWALLE-----QEHQEKLR----------QWNLEDLAREQQRRWV------ 535
EE Q+R++ L E QE QE+ R +W LE+ R+++R +
Sbjct: 837 EEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEE-ERKRRRHTLYAKPAL 895
Query: 536 --QLEKEQESPRREPEQL--GEDVERRIFTPTSRWRDLE--KAELSLVPAPSRTQSAHQS 589
QL KEQ+ + E E+L E +RR ++R+ E + E + R + Q
Sbjct: 896 QEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQE 955
Query: 590 RRPHLPMSPSTQQPALGKQRPMSSVEFTYRPRTRRVPTKPKKSASFPVTGTSIRRLTWPS 649
R QQ K+ + E P RR + KK +L
Sbjct: 956 RERQYRKDKKLQQ----KEEQLLGEE----PEKRRRQEREKKYREEEELQQEEEQLLREE 1007
Query: 650 LQISPANIKKKVYHMDMEAQRKNLQLLSEESELRLPHYLRSKALELTTTTMELGALRLQY 709
+ ++ Y E Q++ QLL EE E R RLQ
Sbjct: 1008 REKRRRQEWERQYRKKDELQQEEEQLLREEREKR----------------------RLQ- 1044
Query: 710 LCHKYIFYRRLQSLRQEAINHVQIMKETEASYKAQNLYIFLENIDRLQSLRLQAWTDKQK 769
+ YR + L+QE + +ET + + Y E + + + L+ +K++
Sbjct: 1045 --ERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRR 1102
Query: 770 GLEEKHREC 778
+E+ R+C
Sbjct: 1103 -RQERERQC 1110
Score = 45.4 bits (106), Expect = 2e-04
Identities = 41/161 (25%), Positives = 82/161 (50%), Gaps = 7/161 (4%)
Query: 422 DRRFPKKWERPVAESLGHKDKDQEDYFQKGGLQIKF-HCSKQLSLESSRQVTSESQ--EE 478
DR+F ++ ++ + K +++E ++ + KF +QL E R+ E Q +E
Sbjct: 1413 DRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQE 1472
Query: 479 PWEEEFGREMRRQLWLEEEEMW--QQRQKKWALLEQEHQEKLRQWNLED--LAREQQRRW 534
E++ R+ R + +LEEE+ Q+R +K+ E QE R++ E+ L R+Q++R
Sbjct: 1473 REEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRK 1532
Query: 535 VQLEKEQESPRREPEQLGEDVERRIFTPTSRWRDLEKAELS 575
E++Q + +Q +D +R+ ++ E+ +LS
Sbjct: 1533 FLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLS 1573
Score = 45.4 bits (106), Expect = 2e-04
Identities = 42/164 (25%), Positives = 75/164 (45%), Gaps = 21/164 (12%)
Query: 461 KQLSLESSRQVTSESQ--EEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQ--- 515
+QL + R+ E Q +E E++ R+ R + + EEE+ ++++++ L++E Q
Sbjct: 1659 QQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRR 1718
Query: 516 ----------EKLRQWNLEDLAREQQRRWVQLEKEQESPRREPEQLGEDVERRIFTPTSR 565
E+LRQ ++ R Q+R LE+EQ P RE +QL R F +
Sbjct: 1719 QELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQ 1778
Query: 566 WRDLEKAELSLVPAPSRTQSAHQSRRPHLPMSPSTQQPALGKQR 609
R E+ E L R+Q + + R + ++ L Q+
Sbjct: 1779 LRQ-EREEQQL-----RSQESDRKFREEEQLRQEREEQQLRPQQ 1816
Score = 44.7 bits (104), Expect = 4e-04
Identities = 94/409 (22%), Positives = 159/409 (38%), Gaps = 41/409 (10%)
Query: 161 EGQKKRSQVSKRTFWQGWQGRSPQTSPSHPQPLSPEQMLQDQHTMNTKA-----SEVTSM 215
E + KR Q +R W R +T H Q +Q+ +DQ + E
Sbjct: 444 EQRLKREQEERRD----WLKREEETE-RHEQERRKQQLKRDQEEERRERWLKLEEEERRE 498
Query: 216 LQELLDSTMFSKGEVRAIRYMATVVEN--LNKALILQHKENRSLETKYRHLQMQATKELS 273
QE + + + E R + + E L + L + + R E + L + ++
Sbjct: 499 QQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRL 558
Query: 274 SQRLHFQQFMEVLESRRDALLKQVEILGGRYHDLLLMKQA--LEFQLKKAQNATGQAEDL 331
Q Q+ E RRD LLK+ E R L +Q LE +LK+ + + E+
Sbjct: 559 EQERREQRLKREQEERRDQLLKREE---ERRQQRLKREQEERLEQRLKREEVERLEQEER 615
Query: 332 AEVSVDSPGPSERETLPRKETVMEESQQEPMKEEQLFSPLPPSPMAMIRDSGAIAAGHQP 391
E + P E R++ +++ +QE +++QL ++ Q
Sbjct: 616 REQRLKREEPEEE----RRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQR 671
Query: 392 LSTMTVRSRVADVFGSKDTESLEPVLLPLVDRRFPKKWERPVAESLGHKDKDQEDYFQKG 451
L R ++ E + R PK W+ + D Q + +
Sbjct: 672 LKREHEEERREQELAEEEQEQARE----RIKSRIPK-WQWQLESEA---DARQSKVYSRP 723
Query: 452 GLQIKFHCSKQLSLESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLE 511
Q + +Q E R+ SE Q W+EE R R+Q +EEE Q+R W
Sbjct: 724 RKQ-EGQRRRQEQEEKRRRRESELQ---WQEE-ERAHRQQ---QEEE--QRRDFTWQWQA 773
Query: 512 QEHQEKLRQ-WNLEDLAREQQRRWVQLEKEQESPRRE-PEQLGEDVERR 558
+E E+ RQ + REQ+ R ++ E+ Q+ +R PE+ ++ RR
Sbjct: 774 EEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRR 822
Score = 44.7 bits (104), Expect = 4e-04
Identities = 43/155 (27%), Positives = 76/155 (49%), Gaps = 27/155 (17%)
Query: 422 DRRFPKKWERPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESS----------RQV 471
DR+F ++ ++ + K +E ++ L+ KF +QL E+ R++
Sbjct: 1690 DRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKI 1749
Query: 472 TSESQEEPWEEE--FGREMRRQLWLEEEEMWQQRQKKWALLEQE------HQEKLRQWNL 523
E Q P EE R+ R + + EEE++ Q+R+++ L QE +E+LRQ
Sbjct: 1750 LEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQ-QLRSQESDRKFREEEQLRQERE 1808
Query: 524 EDLAREQQR----RW----VQLEKEQESPRREPEQ 550
E R QQR RW +QLE++++ R+E ++
Sbjct: 1809 EQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDR 1843
Score = 41.6 bits (96), Expect = 0.003
Identities = 82/426 (19%), Positives = 153/426 (35%), Gaps = 78/426 (18%)
Query: 164 KKRSQVSKRTFWQGWQGRSPQTSPSHPQPLSPEQ---MLQDQHTMNTKASEVTSMLQELL 220
++ + +R W+ + + Q L E+ LQ++ + E+ ++LL
Sbjct: 1005 REEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLL 1064
Query: 221 DSTMFSKGEVRAIRYMATVVENLNKALILQHKENRSL-----ETKYRHLQMQATKELSSQ 275
GE R R + K LQ +E + L + + + + Q +E Q
Sbjct: 1065 -------GEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQ 1117
Query: 276 RLHFQQFMEVLESRRDALLKQVEILGGRYHDLLLMKQALEFQLKKAQNATGQAEDLAEVS 335
+ Q E E RR +Q LE Q ++ + + E L
Sbjct: 1118 QEEEQLLREEREKRR--------------------RQELERQYREEEEVQQEEEQLLR-- 1155
Query: 336 VDSPGPSERETLPRKETVMEESQQEPMKEEQLFSPLPPSPMAMIRDSGAIAAGHQPLSTM 395
+ P R+ L R+ EE QQE EEQL L ++ + L
Sbjct: 1156 -EEPEKRRRQELERQYREEEELQQE---EEQL---LREEQEKRRQERERQYREEEELQRQ 1208
Query: 396 TVRSRVADVFGSKDTESLEPVLLPLVDRRFPKKWERPVAESLGHKDKDQEDYFQKGGLQI 455
+ R D D+R KW+ + ++E+ + +
Sbjct: 1209 KRKQRYRDE-----------------DQRSDLKWQW---------EPEKENAVRDNKVYC 1242
Query: 456 KFHCSKQLSLESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQ 515
K ++Q Q+ ++ + G + R +E WQQR + + EQ +
Sbjct: 1243 KGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDRE-QERRRWQQRDRHFPEEEQLER 1301
Query: 516 EKLRQWNLEDLAREQQRRWVQLEKEQESPR-------REPEQLGEDVERRIFTPTSRWRD 568
E+ ++ D +++++ ++ E+E++ R RE EQL ++ E + R R
Sbjct: 1302 EEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRK 1361
Query: 569 LEKAEL 574
+ EL
Sbjct: 1362 FREEEL 1367
Score = 40.4 bits (93), Expect = 0.007
Identities = 83/389 (21%), Positives = 154/389 (39%), Gaps = 72/389 (18%)
Query: 160 IEGQKKRSQVSKRTFWQGWQGRSPQTSPSHPQPLSPEQMLQDQHTMNTKASEVTSMLQEL 219
+E QK R Q +R F + Q Q +Q+ Q++ + K E +LQE
Sbjct: 1583 LEEQKVRRQEQERKFMEDEQQLRRQEGQ--------QQLRQER---DRKFREDEQLLQER 1631
Query: 220 LDSTMFSKGEVRAIRYMATVVENLNKALILQHKENRSLETKYRHLQMQATKELSSQRLHF 279
+ + + R + + L+H +R K+R + Q +E Q+L
Sbjct: 1632 EEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDR----KFRE-EEQLLQEGEEQQLRR 1686
Query: 280 QQFMEVLESRRDALLKQVEILGGRYHDLLLMKQALEFQLKKAQNATGQAEDLAEVSVDSP 339
Q+ L +Q + L +Q LE + ++ + +
Sbjct: 1687 QERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQE------------ 1734
Query: 340 GPSERETLPRKET---VMEESQQEPMKEEQLFSPLPPSPMAMIRDSGAIAAGHQPLSTMT 396
+E+E L R+E ++EE Q P +EEQ R+ + Q
Sbjct: 1735 --TEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERD--RKFREEEQL---RQEREEQQ 1787
Query: 397 VRSRVADVFGSKDTESLEPVLLPLVDRRFPKKWERPVAESLGHKDKDQEDYFQKGGLQIK 456
+RS+ +D R+F ++ E L + ++Q+ Q+ + +
Sbjct: 1788 LRSQESD-------------------RKFREE------EQLRQEREEQQLRPQQRDGKYR 1822
Query: 457 FHCSKQLSLESSRQVTSESQEEPW--EEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEH 514
+ +QL LE Q + ++ + EE+F + + + EE+E+WQ+ ++K QE
Sbjct: 1823 WE-EEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRR--EEQELWQEEEQK---RRQER 1876
Query: 515 QEKLRQWNLEDLAREQQR-RWVQLEKEQE 542
+ KLR+ ++ +E+QR R V K QE
Sbjct: 1877 ERKLREEHIRRQQKEEQRHRQVGEIKSQE 1905
Score = 37.4 bits (85), Expect = 0.063
Identities = 66/349 (18%), Positives = 126/349 (36%), Gaps = 30/349 (8%)
Query: 435 ESLGHKDKDQEDY--FQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWEEEFGREMRRQL 492
ESL + +ED F+ Q++ ++ + Q ++ E E+ R +R
Sbjct: 107 ESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDR 166
Query: 493 WLEEEEMWQQRQ----KKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKEQESPRREP 548
+EE+W+QRQ ++ E+E + + E+ E+Q R +L + + R E
Sbjct: 167 QRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEK 226
Query: 549 EQLGEDVERRIFTPTSRWRDLEKAELSLVPAPSRTQSAHQSRRPHLPMSPSTQQPALGKQ 608
+Q + + R+F ++ K E L + Q R+ L Q
Sbjct: 227 QQQRRERQDRVFQEEEE-KEWRKRETVLRKEEEKLQEEEPQRQREL-------------Q 272
Query: 609 RPMSSVEFTYRPRTRRVPTKPKKSASFPVTGTSIRRLTWPSLQISPANIKKKVYHMDMEA 668
+ R RR + ++ +RR + +++ + +
Sbjct: 273 EEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQE 332
Query: 669 QRKNLQLLSEESELRLPHYLRSKALELTTTTMELGALRLQYLCHKYIFYRRLQSLRQEAI 728
+R+ QL E+ E R R + E R Q L + RR Q LR+E
Sbjct: 333 ERREQQLRREQEERREQQLRREQEEE----------RREQQLRREQEEERREQQLRREQQ 382
Query: 729 NHVQIMKETEASYKAQNLYIFLENIDRLQSLRLQAWTDKQKGLEEKHRE 777
+ E + + + + R Q LR + +++ L + E
Sbjct: 383 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEE 431
Score = 37.4 bits (85), Expect = 0.063
Identities = 76/378 (20%), Positives = 145/378 (38%), Gaps = 36/378 (9%)
Query: 422 DRRFPKKWERPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWE 481
DR+F ++ ++ + K ++QE Q+ + +QL + ++ + +++
Sbjct: 1484 DRKFLEEEQQLRRQERDRKFREQELRSQEPERKF-LEEEQQLHRQQRQRKFLQEEQQLRR 1542
Query: 482 EEFGREMR--RQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWV---- 535
+E G++ R R EEE +Q +++ L QE K R + +EQ+R+++
Sbjct: 1543 QERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQ 1602
Query: 536 ---------QLEKEQESPRREPEQLGEDVERRIFTPTSRWRDLEKAELSLVPAPSRTQSA 586
QL +E++ RE EQL ++ E + R R + E L Q
Sbjct: 1603 QLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLR 1662
Query: 587 HQSRRPHLPMSPSTQQPALGKQRPMSSVEFTYRPRTRRVP-TKPKKSASFPVTGTSIRRL 645
H R Q+ G+++ + E + R + ++ F +RR
Sbjct: 1663 HDRDRKFREEEQLLQE---GEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQ 1719
Query: 646 TWPSLQISPANIKKKVYHMDMEAQRKNLQLLSEE------SELRLPHYLRSKAL---ELT 696
++++ + Q + ++L EE E +L R + E
Sbjct: 1720 ELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQL 1779
Query: 697 TTTMELGALRLQYLCHKYIFYRRLQSLRQEAINHVQIMKETEASYKAQNLYIFLENIDRL 756
E LR Q K +R + LRQE ++ + Y+ + + LE
Sbjct: 1780 RQEREEQQLRSQESDRK---FREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEE---- 1832
Query: 757 QSLRLQAWTDKQKGLEEK 774
Q RL+ D+Q EE+
Sbjct: 1833 QEQRLRQERDRQYRAEEQ 1850
Score = 36.2 bits (82), Expect = 0.14
Identities = 35/134 (26%), Positives = 63/134 (47%), Gaps = 15/134 (11%)
Query: 431 RPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLE-SSRQVTSESQEEPWEEEFGREMR 489
R + E + + +E ++ KF +QL E +Q+ S+ + + EE E
Sbjct: 1747 RKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREE---EQL 1803
Query: 490 RQLWLEEEEMWQQRQKKWALLEQ-----EHQEKLRQWNLEDLAREQQRRWVQLEKEQESP 544
RQ E++ QQR K+ E+ E +++LRQ R++Q R + QE
Sbjct: 1804 RQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQ------ERDRQYRAEEQFATQEKS 1857
Query: 545 RREPEQLGEDVERR 558
RRE ++L ++ E++
Sbjct: 1858 RREEQELWQEEEQK 1871
Score = 33.5 bits (75), Expect = 0.91
Identities = 31/136 (22%), Positives = 55/136 (40%), Gaps = 12/136 (8%)
Query: 430 ERPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPW-EEEFGREM 488
E+ + + K +++E + KF E +QV + +E + EEE
Sbjct: 1405 EQQLRQDRDRKFREEEQQLSRQERDRKFR-------EEEQQVRRQERERKFLEEEQQLRQ 1457
Query: 489 RRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKEQESPRR-- 546
R EEE Q +++ L QE K + + +E+ R++ + E + P R
Sbjct: 1458 ERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKF 1517
Query: 547 --EPEQLGEDVERRIF 560
E +QL +R F
Sbjct: 1518 LEEEQQLHRQQRQRKF 1533
Score = 32.7 bits (73), Expect = 1.5
Identities = 33/101 (32%), Positives = 46/101 (45%), Gaps = 25/101 (24%)
Query: 456 KFHCSKQLSLESSRQVTSESQEEP---WEEEFGREMRRQLWLEEEE--MWQQRQKKWALL 510
KF +QL E Q Q + WEEE QL LEE+E + Q+R +++
Sbjct: 1796 KFREEEQLRQEREEQQLRPQQRDGKYRWEEE-------QLQLEEQEQRLRQERDRQYRAE 1848
Query: 511 EQ-EHQEKLRQWNLEDLAREQQRRWVQLEKEQESPRREPEQ 550
EQ QEK R RE+Q W +E+E RR+ +
Sbjct: 1849 EQFATQEKSR--------REEQELW----QEEEQKRRQERE 1877
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 50.4 bits (119), Expect = 7e-06
Identities = 84/376 (22%), Positives = 154/376 (40%), Gaps = 38/376 (10%)
Query: 193 LSPEQMLQDQHTMNTKASEVTSMLQELLDSTMFSKGEVRAIRYMATVVENLNKALILQHK 252
L E + Q+Q + + + EL S K EV +R A + LN+AL L
Sbjct: 554 LEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALD-- 611
Query: 253 ENRSLETKYRHLQMQATKELSSQRLHFQQFMEVLESRRDALLKQVEILGGRYHDLLLMKQ 312
+ + LQ++ + R ME E R+AL + R L
Sbjct: 612 ---KVGLNQQLLQLEEENQSVCSR------MEAAEQARNALQVDLAEAEKRREALWEKNT 662
Query: 313 ALEFQLKKAQNATGQAE-DLAEVSVDSPGPSERETLPRKE-----TVMEESQQEPMKEEQ 366
LE QL+KA+ A + + DL ++ + ++ + R + T +E+ QE ++E+
Sbjct: 663 HLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEE 722
Query: 367 LFSPLPPSPMAMIRDSGAIAAGHQPLSTMTVRSRVADVFGSKDTESLEPVLLPLVDRRFP 426
+ + A++R+ A+ Q + R R D+ ++ + L L F
Sbjct: 723 VLARAVQEKEALVREKAALEVRLQAVE----RDR-QDL--AEQLQGLSSAKELLESSLFE 775
Query: 427 KKWERPVAE-SLGHKDKDQEDYFQ-KGGLQIKFHCSKQLSLESSRQVTSESQEEPWE--- 481
+ + V E + G + + Q K +Q + C K L L++ R + ++
Sbjct: 776 AQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLK-LELDTERSQAEQERDAAARQLA 834
Query: 482 --EEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEK 539
E+ G+ Q E+ Q ++KW HQ++L + LE L RE+ ++L++
Sbjct: 835 QAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAK-ALESLEREKMELEMRLKE 893
Query: 540 EQES-----PRREPEQ 550
+Q +RE E+
Sbjct: 894 QQTEMEAIQAQREEER 909
Score = 44.3 bits (103), Expect = 5e-04
Identities = 96/437 (21%), Positives = 176/437 (40%), Gaps = 54/437 (12%)
Query: 197 QMLQDQHTMNTKASEVTSM-LQELLDSTMFSKGEVRAIRYMATVVENLNKA-------LI 248
Q L+ Q M A E+ S+ L++ + +++ + +V+E+L A L
Sbjct: 1445 QELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLT 1504
Query: 249 LQHKENRSLETKYRHLQMQATKELSSQRLHFQQFMEVLESRRDA---LLKQVEILGGRYH 305
+Q ++ R LE K R Q L Q L ++ +++ES+R L KQ+ L
Sbjct: 1505 VQREQIRELE-KDRETQRNV---LEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLAL 1560
Query: 306 DLLLMKQALEFQLKKAQNATGQAE-----------DLAEVSVDSPGPSER-ETLPRKETV 353
+L +E Q K + GQ E DL E S + S + L TV
Sbjct: 1561 ELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTV 1620
Query: 354 M----EESQQEPMKEEQLFSPLPPSPMAMIRDSGAIAAGHQPLSTMTVRSRVADVFGSKD 409
+ +E QE + + L + +D + Q L R +V + ++
Sbjct: 1621 LARELQERDQEVKSQREQIEELQRQKEHLTQD---LERRDQELMLQKERIQVLEDQRTRQ 1677
Query: 410 T----ESLEPVLLPLVDRRFPKKWERPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSL 465
T E LE + L L +R +R + + + K Q+G L+ K +
Sbjct: 1678 TKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKA-QRGSLEHM----KLILR 1732
Query: 466 ESSRQVTSESQEEPWEEEFGREMRRQLWL------EEEEMWQQRQKKWALLEQEHQE--- 516
+ ++V + + +E ++ +QL E + QR+++ +L+Q+ QE
Sbjct: 1733 DKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEARE 1792
Query: 517 --KLRQWNLEDLAREQQRRWVQLEKEQESPRREPEQLGEDVERRIFTPTSRWRDLEKAEL 574
+L++ +L+ E QR Q ++E E+ ++E +Q ER + LE+A +
Sbjct: 1793 QGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHM 1852
Query: 575 SLVPAPSRTQSAHQSRR 591
+L Q + R
Sbjct: 1853 TLKERHGELQDHKEQAR 1869
Score = 35.0 bits (79), Expect = 0.31
Identities = 58/313 (18%), Positives = 127/313 (40%), Gaps = 30/313 (9%)
Query: 264 LQMQATKELSSQRLHFQQFMEVLESRRDALLKQVEILGGRYHDLLLMKQALEFQLKKAQN 323
L + T+EL + Q + L+S+ D +++ LL Q +K
Sbjct: 248 LLLAKTQELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIK 307
Query: 324 ATGQAEDLAEVSVDSPGPSERETLPRKETVMEESQQEPMKEEQLFSPLPPSPMAMIRDSG 383
A + ++ E + E + + ++ +Q+E + +Q+ + M+ +
Sbjct: 308 ALRETVEILETN-------HTELMEHEASLSRNAQEEKLSLQQVIKDIT---QVMVEEGD 357
Query: 384 AIAAGHQPLSTMTVRSRVADVFGSKDTESLEPVLLPLVDRRFPK----KWERPVAESLGH 439
IA G +++ + S + F +D + ++ ++ RR + + + +
Sbjct: 358 NIAQGSGHENSLELDSSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVN 417
Query: 440 KDKDQEDYFQKGGLQIKFHCSKQL---------SLESSRQVTSESQEEPWEEEFGREMRR 490
+ Q D +++ G ++ K +++ +V S S+E ++ E+R+
Sbjct: 418 LLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQ 477
Query: 491 QLWLEEEEMWQQRQKKWALLEQ----EHQEKLRQWNLEDLAREQQR---RWVQLEKEQES 543
QL + E+E W+ R+ L Q + Q++ +Q L RE++R + LE +Q
Sbjct: 478 QLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSE 537
Query: 544 PRREPEQLGEDVE 556
E L E +E
Sbjct: 538 SLSELITLREALE 550
Score = 33.9 bits (76), Expect = 0.69
Identities = 93/429 (21%), Positives = 169/429 (39%), Gaps = 81/429 (18%)
Query: 197 QMLQDQHTMNTKASEVTSMLQELLDSTMFSKGEVRAIRYMATVVENLNKALILQHKENRS 256
Q +++ K + + S L EL ++ + +R + + L+ KEN
Sbjct: 1296 QNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQG-ERELLQAAKEN-- 1352
Query: 257 LETKYRHLQMQATK-------------ELSSQRLHFQQFMEVLESRRD---ALLKQVEIL 300
L + HLQ + +L + R + E +ES R+ AL +Q E+
Sbjct: 1353 LTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELK 1412
Query: 301 GGR----YHDLLLMKQALEFQLKKAQNATGQAEDLAEVSVDSPGPSERETLPRKETVME- 355
+ +L L+ Q L + ++ + GQ ++L + E +L K+ E
Sbjct: 1413 VAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEV 1472
Query: 356 ESQQEPMKE-EQLFSPLPPSPMAMIRDSGAIAAGHQPLSTMTVRSRVADVFGSKDTES-- 412
+ QQE ++E E+ S L PMA + Q L+ R ++ ++ ++T+
Sbjct: 1473 DLQQEQIQELEKCRSVLEHLPMA-------VQEREQKLTVQ--REQIRELEKDRETQRNV 1523
Query: 413 LEPVLLPLVDRRFPKKWERPVAESLGHKDKDQEDYFQKGGLQ------IKFHCSKQLSLE 466
LE LL L + KDQ Q+G +Q + C L LE
Sbjct: 1524 LEHQLLEL-------------------EKKDQMIESQRGQVQDLKKQLVTLECLA-LELE 1563
Query: 467 SSRQVTSESQEEPWEEEFGREMRR----QLWLEEEEMWQQRQKKWA-------------- 508
+ Q+ E E RE +R L L+ EE Q+ Q + +
Sbjct: 1564 ENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLAR 1623
Query: 509 -LLEQEHQEKLRQWNLEDLAREQQRRWVQLEKEQESPRREPEQLGEDVERRIFTPTSRWR 567
L E++ + K ++ +E+L R+++ LE+ + + E++ ++R
Sbjct: 1624 ELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEE 1683
Query: 568 DLEKAELSL 576
DLE+ +LSL
Sbjct: 1684 DLEQIKLSL 1692
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 48.9 bits (115), Expect = 2e-05
Identities = 85/411 (20%), Positives = 162/411 (39%), Gaps = 56/411 (13%)
Query: 414 EPVLLPLVDRRFPKKWERPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLS-----LESS 468
E ++P + RR+ K+ E + K Q D + + H S+++ LE
Sbjct: 2186 EEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVES-----EEHFSEEMESLLDELEKQ 2240
Query: 469 RQVTSESQEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAR 528
++SE +EE EEE E ++ EEEE ++ + + +E+E +EK ++ +
Sbjct: 2241 ESLSSEEEEEREEEEEREE--EEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEE 2298
Query: 529 EQQRRWVQLEKEQESPRREPEQLGEDVERRIFTPTSRWRDLEKAELSLVPAPSRTQSAHQ 588
Q++ V EKE+ E E L ++ E D EK L
Sbjct: 2299 VQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEIL-------------- 2344
Query: 589 SRRPHLPMSPSTQQPALGKQRPMSSVEFTYRPRTRRVPTKPKKSASFPVTGTSIRR---- 644
+ + ++ G++R +S + + R + KS + T++
Sbjct: 2345 KKEKQFKLQEQRRKSLRGRERVLSILRGVPHGKGRAIRLGVLKSPLKKLMSTALEMKEKT 2404
Query: 645 -LTWPSLQISPANIKKKVYHMDMEAQRKNLQLLSEESELR-----LPHYLRSKALELTTT 698
+ P QIS + K V +E RK L + +E E+ +P ++ LE +
Sbjct: 2405 PVPVPEKQISWEDKKATV----VEIPRKFLGTMDKEREVMGKYEPIPPHVLGTVLE--SQ 2458
Query: 699 TMELGALRLQYLCHKYIFYRRLQSLRQEA-----INHVQIMKETEASY-------KAQNL 746
+L + ++ + + LQ A + H +M +TE K Q+
Sbjct: 2459 AQDLKTPFMSHILRRTVEAEELQHKPLGAWWKWFLQHPPLMGQTEVQLPLSQIPAKEQHA 2518
Query: 747 YIFLENIDRLQSLRLQAWTDKQKGLEEKHRECLSSMVTMFPKLQLEWNVHL 797
+ L +++ ++ + + +Q + HR C + + K LEW +HL
Sbjct: 2519 DVSLSDVEWIRHVLERMEAGEQLSRDGFHRLC-QLLKDLASKGNLEW-LHL 2567
Score = 36.6 bits (83), Expect = 0.11
Identities = 38/149 (25%), Positives = 73/149 (48%), Gaps = 23/149 (15%)
Query: 423 RRFPKKWERPVAES------LGHKDKDQEDYFQKGGLQIKFHCSKQ-----LSLESSRQV 471
+ + ++WE+ + + G K +E+ Q+ ++K+ KQ LS +S Q
Sbjct: 1479 KAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDK-KLKWEEWKQVWENMLSSKSKEQQ 1537
Query: 472 TSESQEEPWEEEFGRE-MRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQ 530
+ +E EEE RE ++ + EE+ Q + KWA + H+++ R + R Q
Sbjct: 1538 YKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARI---HRKRAR----AEKKRAQ 1590
Query: 531 QRRWVQLEKEQESPRREPEQLGEDVERRI 559
+ R +L +E+E +E QL ++ ER++
Sbjct: 1591 EER--KLAQEEEKLAQEERQLAQE-ERKL 1616
Score = 35.0 bits (79), Expect = 0.31
Identities = 31/152 (20%), Positives = 68/152 (44%), Gaps = 14/152 (9%)
Query: 442 KDQEDYFQKGGLQIKFHCSKQLSL-ESSRQVTSESQE--------EPWEEEFGREMRRQL 492
K+++ FQK Q + K+ + + R++T E ++ EE+ ++ + +
Sbjct: 1390 KEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKLV 1449
Query: 493 WLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKEQESPRREPEQLG 552
+E WQ +K W +Q H E + W + E ++R +Q E+E + E+L
Sbjct: 1450 MIERTPSWQDWKKAWDEWKQVHGETRKSW--KAWKEEWEKRLLQ---EEEKLHQAGEKLS 1504
Query: 553 EDVERRIFTPTSRWRDLEKAELSLVPAPSRTQ 584
+ E +W + ++ +++ + S+ Q
Sbjct: 1505 PEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQ 1536
Score = 32.0 bits (71), Expect = 2.6
Identities = 81/419 (19%), Positives = 153/419 (36%), Gaps = 96/419 (22%)
Query: 149 IESLTALCSTLIEGQKKRSQVSKRTFWQGWQGRSPQTSPSHPQPLSP---------EQML 199
+E + L +++ + K + + WQ W+ + H + +++L
Sbjct: 1431 VEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLL 1490
Query: 200 QDQHTMNTKASEVTSMLQELLDSTMFSKGEVRAIRYMATVVENLNKALILQHKENRSLET 259
Q++ ++ +A E S +E+L K E V EN+ ++S E
Sbjct: 1491 QEEEKLH-QAGEKLSPEEEMLQEDKKLKWEE-----WKQVWENM--------LSSKSKEQ 1536
Query: 260 KYRHLQMQATKELSSQRLHFQQFMEVLESRRDALLKQVEILGGRYHDLLLMKQALEFQLK 319
+Y+ + + T E R ++ +V E +R Q E R H ++ + K
Sbjct: 1537 QYKD-EEEVTLEEEVSREGEEKEQQVTEEQRHI---QEEHKWARIH-----RKRARAEKK 1587
Query: 320 KAQNATGQAEDLAEVSVDSPGPSERETLPRKETVMEESQQEPMKEEQLFSPLPPSPMAMI 379
+AQ A+ E E L ++E + QE K Q + + M
Sbjct: 1588 RAQEERKLAQ-------------EEEKLAQEE---RQLAQEERKLAQAYVKITQDDREMA 1631
Query: 380 RDSGAIAAGHQPLSTMTVRSRVADVFGSKDTESLEPVLLPLVDRRFPKKWERPVAESLGH 439
+ G A + L+ G K ++ E L ++ KKWE+ E
Sbjct: 1632 QAEGKFAQKEETLAQR----------GEKLSQEAEK--LAQKRKKLAKKWEKVARE---- 1675
Query: 440 KDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWEE-EFGREMRRQLWLEEEE 498
+E +KGG K K + + ++ Q W+E E +E+ W EE
Sbjct: 1676 ----EEKLAKKGG---KLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEEL 1728
Query: 499 MWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQR---RWVQLEKEQESPRREPEQLGED 554
W++ E+L +E+ + +L +E+E+ + E+L E+
Sbjct: 1729 SWKE---------------------EELNQEEGKLVEEKKKLAEEEEALAWQREKLSEE 1766
Score = 31.6 bits (70), Expect = 3.4
Identities = 21/94 (22%), Positives = 51/94 (54%), Gaps = 2/94 (2%)
Query: 454 QIKFHCSKQLSLESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQE 513
+ K ++L ++ ++ ++ P EEE R QL ++ ++ Q+R++ +E+
Sbjct: 1767 ETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEEL 1826
Query: 514 HQEKLRQWNLEDLAREQQRRWVQLEKEQESPRRE 547
+ K+ + ++LA+E++ + EKE+ + R+E
Sbjct: 1827 TKNKMILYQKKNLAQEKKN--LAQEKEKLAQRKE 1858
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 48.1 bits (113), Expect = 4e-05
Identities = 76/374 (20%), Positives = 162/374 (43%), Gaps = 58/374 (15%)
Query: 202 QHTMNTKASEVTSMLQELLDSTMFSKGEVRAIRYMATVVENLNKALILQHKENRSLETK- 260
QH + E ++ L DS F+ +A+ +AT + ++ + KE +L +
Sbjct: 138 QHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLEL 197
Query: 261 YRHLQMQATKELSSQRLHFQQFMEVLESRRDALLKQVEILGGRYH--DLLLMKQALEFQL 318
YR+ +EL + Q+ ++++ES + + V+ L + LLL +Q L+ +
Sbjct: 198 YRNTITD--EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEA 255
Query: 319 ----KKAQNATGQAEDLAEVSV--DSPGPSERETLPRKETVMEESQQEPMKEEQLFSPLP 372
K+ Q+ + + + E + + + E + R+E ++E +++ ++E+
Sbjct: 256 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEE------ 309
Query: 373 PSPMAMIRDSGAIAAGHQPLSTMTVRSRVADVFGSKDTESLEPVLLPLVDRRFPKKWE-- 430
IR+ R ++ K+ + + R+ WE
Sbjct: 310 -----KIREQEE------------KMRRQEEMMWEKEEK---------MRRQEEMMWEKE 343
Query: 431 ---RPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWEEEFGRE 487
R + E + ++K +E +K + K ++ + ++ E + EE+ RE
Sbjct: 344 EKIRELEEKMHEQEKIREQE-EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI-RE 401
Query: 488 MRRQLWLEEEEMWQQRQKKWALLE--QEHQEKLRQWNLEDLAREQQRRWVQLEKEQESPR 545
+ +EE+M +Q +K W E QE +EK+R+ E+ REQ+++ +EQE
Sbjct: 402 QEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRR--QEEKIREQEKK----IREQEEKI 455
Query: 546 REPEQLGEDVERRI 559
RE E++ ++ E ++
Sbjct: 456 REQEEMMQEQEEKM 469
Score = 45.8 bits (107), Expect = 2e-04
Identities = 88/407 (21%), Positives = 156/407 (38%), Gaps = 49/407 (12%)
Query: 187 PSHPQ----PLSPEQMLQDQHTMNTKASEVTSMLQELLDSTMFSKGEVRAIRYMATVVEN 242
P+HP P P + + T +K +E L + T S G + +
Sbjct: 22 PTHPHLPTHPHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNG 81
Query: 243 LNKALILQ---HKENRSLETKYRH---------LQMQATKELSSQRLHFQQFMEVLESRR 290
N H + ++H Q+Q + L+ Q+ Q + +
Sbjct: 82 TNPETTTSGGCHSPEDEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAV 141
Query: 291 DALLKQVEILGGRYHDLLL----MKQALEFQLKKAQNATGQAEDLAEVSVDSPGPSERET 346
L + L R HD ++QAL + + A E+L + R T
Sbjct: 142 KQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNT 201
Query: 347 LPRKETVMEESQQEPMKEEQLFSPLPPSPMAMIRDSGAIAAGHQPLSTMTVRSRVADVFG 406
+ +E ++E + ++ QL +++ + L AD G
Sbjct: 202 ITDEE--LKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLG 259
Query: 407 SKDTESLEPVLLPLVDRRFPKKWERPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLE 466
K+ +S+ L V+ + W R + + K QE+ Q+ +I+ ++ +
Sbjct: 260 -KELQSVSAKLQAQVEEN--ELWNR-LNQQQEEKMWRQEEKIQEREEKIQ---EQEEKIR 312
Query: 467 SSRQVTSESQEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEH-QEKLRQW---- 521
+ +E WE+E +MRRQ EE MW++ +K L E+ H QEK+R+
Sbjct: 313 EQEEKMRRQEEMMWEKE--EKMRRQ----EEMMWEKEEKIRELEEKMHEQEKIREQEEKR 366
Query: 522 NLEDLAREQQRR-------WVQLEK--EQESPRREPEQLGEDVERRI 559
E+ REQ++R W Q EK EQE RE E++ ++ E ++
Sbjct: 367 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKM 413
Score = 45.4 bits (106), Expect = 2e-04
Identities = 29/112 (25%), Positives = 56/112 (50%), Gaps = 3/112 (2%)
Query: 462 QLSLESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQW 521
+L+ + ++ + ++ EE +E ++ +EE+M +Q + W E+ +++ W
Sbjct: 281 RLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW 340
Query: 522 NLEDLAREQQRRWVQLEK--EQESPRREPEQLGEDVERRIFTPTSRWRDLEK 571
E+ RE + + + EK EQE R+E E++ E E+R WR EK
Sbjct: 341 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ-EKRQEQEAKMWRQEEK 391
Score = 40.0 bits (92), Expect = 0.010
Identities = 33/129 (25%), Positives = 61/129 (47%), Gaps = 12/129 (9%)
Query: 424 RFPKKWERPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWE-- 481
R +K R E + +++ ++ +K G Q C ++ ++ + +E+ E
Sbjct: 442 REQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQE 501
Query: 482 ------EEFGREMRRQLWLEEEEMWQQRQKKWALLE--QEHQEKLRQWNLEDLAREQQRR 533
EE RE + +EE+MW+Q +K E QE +EK+R+ E+ REQ+ R
Sbjct: 502 KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR--QEEKMREQEVR 559
Query: 534 WVQLEKEQE 542
Q E++ +
Sbjct: 560 LRQQEEKMQ 568
Score = 37.0 bits (84), Expect = 0.082
Identities = 29/118 (24%), Positives = 59/118 (50%), Gaps = 12/118 (10%)
Query: 440 KDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEM 499
K ++QE+ Q+ ++ K E+ Q E +EE RE +++ +EE++
Sbjct: 454 KIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRR--QEEKIREQEKKIREQEEKI 511
Query: 500 WQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKEQESPRREPEQLGEDVER 557
+Q + + QE +EK+ W E+ EQ+ + +++++E RR+ E++ E R
Sbjct: 512 REQEE-----MMQEQEEKM--WEQEEKMCEQEEK---MQEQEEKMRRQEEKMREQEVR 559
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 47.0 bits (110), Expect = 8e-05
Identities = 77/378 (20%), Positives = 161/378 (42%), Gaps = 53/378 (14%)
Query: 312 QALEFQLKKAQNATGQAEDLAEVSVDSPGPSERETL-PRKETVMEESQQEPMKEEQLFSP 370
Q + Q ++ Q+ GQ + + PG + L P+ + +M S + + +QL
Sbjct: 3735 QQQQQQQQQQQHLLGQVA-IQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQ 3793
Query: 371 LPPSPMAMI----------RDSGAIAAGHQPLSTMTVRSRV-ADVFGSKDTESLEPVLLP 419
P P M+ + GA+ + +SRV + ++ + L L
Sbjct: 3794 PPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLV 3853
Query: 420 LVDRRFPKKWERPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEP 479
++ ++ + G Q G Q K SL+ +Q Q++
Sbjct: 3854 TAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSG--QPKLSAQPMGSLQQLQQQQQLQQQQQ 3911
Query: 480 WEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEK 539
+++ +++++Q L+++++ QQ+Q++ L+Q+ Q++L+Q + L ++QQ++ Q ++
Sbjct: 3912 LQQQQQQQLQQQQQLQQQQLQQQQQQQ--QLQQQQQQQLQQ-QQQQLQQQQQQQQQQFQQ 3968
Query: 540 EQESPRREPEQLG-EDVERRIFTPTSRWRDLEKAELSLVPAPSRTQSAHQSRRPHLPMSP 598
+Q+ +Q+G + R + +P + ++ +++L P H S SP
Sbjct: 3969 QQQQ-----QQMGLLNQSRTLLSPQQQ----QQQQVALGPGMPAKPLQHFS-------SP 4012
Query: 599 STQQPAL---GKQR----PMSSVEFTYRPRTRR-----VPTKPKKSASFP------VTGT 640
P L GK++ P S E T P T + + T P+ A+ P ++G
Sbjct: 4013 GALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGD 4072
Query: 641 SIRRLTWPSLQISPANIK 658
S L P Q P++++
Sbjct: 4073 SQLLLVQPQPQPQPSSLQ 4090
>gi|38176300 nestin [Homo sapiens]
Length = 1621
Score = 45.8 bits (107), Expect = 2e-04
Identities = 83/387 (21%), Positives = 142/387 (36%), Gaps = 57/387 (14%)
Query: 200 QDQHTMNTKASEVTSMLQELLDSTMFSKGEVRAIRYMATVVENLNKALILQHKENRSLET 259
Q T+ + E L+E L++ + E + + VV L K + Q K
Sbjct: 563 QSHETLERENQECPRSLEEDLETLKSLEKENKELLKDVEVVRPLEKEAVGQLKPTGK--- 619
Query: 260 KYRHLQMQATKELSSQRLHFQQFMEVLESRRDALL-------KQVEILGGRYHDLLLMKQ 312
+ T+ L S + Q+ M+ LE + L + V L L +++
Sbjct: 620 -------EDTQTLQSLQKENQELMKSLEGNLETFLFPGTENQELVSSLQENLESLTALEK 672
Query: 313 ALEFQLKKAQNATGQAEDLAEVSVDSPGPSERETLPRKETV--MEESQQEPMKEEQLFSP 370
+ L+ + G E L ++ ++ P KE +E+ QEP+K +
Sbjct: 673 ENQEPLRSPE--VGDEEALRPLTKENQEPLRSLEDENKEAFRSLEKENQEPLKTLEEEDQ 730
Query: 371 LPPSPMAMIRDSGAIAAGHQPLSTMTVRSRVADV----FGSKDTESLEPVLLPLVDRRFP 426
P+ + Q T+ + G +D +L P VD
Sbjct: 731 SIVRPLETENHKSLRSLEEQDQETLRTLEKETQQRRRSLGEQDQMTLRPP--EKVDLEPL 788
Query: 427 KKWERPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWEEEFGR 486
K ++ +A L +++++ F K + K L E + S QE E
Sbjct: 789 KSLDQEIARPLENENQE----FLKSLKEESVEAVKSLETEILESLKSAGQEN-LETLKSP 843
Query: 487 EMRRQLWLEEE-----------------EMWQQRQKKWALLEQEHQEKLRQ---WNLEDL 526
E + LW EE E + Q+ + LLE+E+QE LR WNLE+L
Sbjct: 844 ETQAPLWTPEEINQGAMNPLEKEIQEPLESVEVNQETFRLLEEENQESLRSLGAWNLENL 903
Query: 527 AREQQRRWVQLEKEQESPRREPEQLGE 553
+ +++KE + E E LG+
Sbjct: 904 RSPE-----EVDKESQRNLEEEENLGK 925
>gi|219803769 trichoplein [Homo sapiens]
Length = 498
Score = 45.8 bits (107), Expect = 2e-04
Identities = 81/405 (20%), Positives = 170/405 (41%), Gaps = 33/405 (8%)
Query: 236 MATVVENLNKALILQHKENRSLETKYRHLQMQATKELSSQRLHFQQFMEVLESRRDALLK 295
+A +E L ++ LQ + R +H ++++ KE ++L +Q + + + L+
Sbjct: 98 LARELEELRLSMNLQERRIRE-----QHGKLKSAKE-EQRKLIAEQLLYEHWKKNNPKLR 151
Query: 296 QVEILGGRYHDLLLMKQALEFQLKKAQNATGQAEDLAEVSVDSPGPSERETLPRKETVME 355
++E+ + H ++ ++ + KK Q AT + E+ + + + RE L R + E
Sbjct: 152 EMELDLHQKH--VVNSWEMQKEEKKQQEATAEQEN--KRYENEYERARREALERMKAEEE 207
Query: 356 ESQ-QEPMKEEQLFSPLPPSPMAMI------RDSGAIAAGHQPLSTMTVRSRVADVFGSK 408
Q ++ ++ E L + + + ++ + L + + + F K
Sbjct: 208 RRQLEDKLQAEALLQQMEELKLKEVEATKLKKEQENLLKQRWELERLEEERKQMEAFRQK 267
Query: 409 DTESLEPVLLPLVDRRFPKKWERPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESS 468
L L + + ++ ++ + E L + + +K + H +++ + +
Sbjct: 268 --AELGRFLRHQYNAQLSRRTQQ-IQEELEADRRILQALLEKEDESQRLHLARREQVMAD 324
Query: 469 RQVTSESQEEPWEEEFGREMRRQLWLEEE--EMWQQRQKKWALLEQEHQEKLRQWNLEDL 526
++ EE + E RE Q+ L EE EMW++R+ +WA E+ +++L L
Sbjct: 325 VAWMKQAIEEQLQLERAREAELQMLLREEAKEMWEKREAEWA-RERSARDRLMSEVLTGR 383
Query: 527 AREQQRRWVQLEKEQESPRREPEQLGEDVE------RRIFTPTSRWRDLEKAELSLVPAP 580
++ Q + Q + QE + EQL ++E RR + + + K EL A
Sbjct: 384 QQQIQEKIEQNRRAQEESLKHREQLIRNLEEVRELARREKEESEKLKSARKQELEAQVAE 443
Query: 581 SRTQS--AHQSRRPHLPMSPSTQQ--PALGKQRPMSSVEFTYRPR 621
R Q+ A Q + +Q AL +Q + E YRP+
Sbjct: 444 RRLQAWEADQQEEEEEEEARRVEQLSDALLQQEAETMAEQGYRPK 488
Score = 33.5 bits (75), Expect = 0.91
Identities = 55/277 (19%), Positives = 111/277 (40%), Gaps = 9/277 (3%)
Query: 459 CSKQLSLESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKL 518
CS + + SS+ S E+ E RR L E++ Q Q++ LL +E +E
Sbjct: 47 CSSKQAEWSSKTSYQRSMHAYQREKMKEEKRRSLEARREKLRQLMQEEQDLLARELEELR 106
Query: 519 RQWNLEDLAREQQRRWVQLEKEQESPRREPEQLGEDVERRIFTPTSRWRDLEKAELSLVP 578
NL++ +Q ++ KE++ + L E ++ P R +L+ + +V
Sbjct: 107 LSMNLQERRIREQHGKLKSAKEEQRKLIAEQLLYEHWKKN--NPKLREMELDLHQKHVVN 164
Query: 579 APSRTQSAHQSRRPHLPMSPSTQQPALGKQRPMSSVEFTYRPRTRRVPTKPKKSASF-PV 637
+ + + + + + R + R++ K + A +
Sbjct: 165 SWEMQKEEKKQQEATAEQENKRYENEYERARREALERMKAEEERRQLEDKLQAEALLQQM 224
Query: 638 TGTSIRRLTWPSLQISPANIKKKVYHMD-MEAQRKNLQLLSEESELR--LPHYLRSKALE 694
++ + L+ N+ K+ + ++ +E +RK ++ +++EL L H ++
Sbjct: 225 EELKLKEVEATKLKKEQENLLKQRWELERLEEERKQMEAFRQKAELGRFLRHQYNAQLSR 284
Query: 695 LTTTTM-ELGALR--LQYLCHKYIFYRRLQSLRQEAI 728
T EL A R LQ L K +RL R+E +
Sbjct: 285 RTQQIQEELEADRRILQALLEKEDESQRLHLARREQV 321
Score = 31.6 bits (70), Expect = 3.4
Identities = 47/194 (24%), Positives = 81/194 (41%), Gaps = 28/194 (14%)
Query: 193 LSPEQMLQDQHTMNTKASEVTSMLQELLDSTMFSKGEVRAI----RYMATVVENLNKALI 248
L E +LQ + K E T + +E ++ + + E+ + + M +
Sbjct: 215 LQAEALLQQMEELKLKEVEATKLKKEQ-ENLLKQRWELERLEEERKQMEAFRQKAELGRF 273
Query: 249 LQHKEN-----------RSLETKYRHLQMQATKELSSQRLHF---QQFMEVLESRRDALL 294
L+H+ N LE R LQ KE SQRLH +Q M + + A+
Sbjct: 274 LRHQYNAQLSRRTQQIQEELEADRRILQALLEKEDESQRLHLARREQVMADVAWMKQAIE 333
Query: 295 KQVEILGGRYHDL--LLMKQALEFQLKKAQNATGQAEDLAEVSVDSPGPSERETLPRKET 352
+Q+++ R +L LL ++A E K+ +AE E S SE T R++
Sbjct: 334 EQLQLERAREAELQMLLREEAKEMWEKR------EAEWARERSARDRLMSEVLT-GRQQQ 386
Query: 353 VMEESQQEPMKEEQ 366
+ E+ +Q +E+
Sbjct: 387 IQEKIEQNRRAQEE 400
>gi|14150056 trichoplein [Homo sapiens]
Length = 498
Score = 45.8 bits (107), Expect = 2e-04
Identities = 81/405 (20%), Positives = 170/405 (41%), Gaps = 33/405 (8%)
Query: 236 MATVVENLNKALILQHKENRSLETKYRHLQMQATKELSSQRLHFQQFMEVLESRRDALLK 295
+A +E L ++ LQ + R +H ++++ KE ++L +Q + + + L+
Sbjct: 98 LARELEELRLSMNLQERRIRE-----QHGKLKSAKE-EQRKLIAEQLLYEHWKKNNPKLR 151
Query: 296 QVEILGGRYHDLLLMKQALEFQLKKAQNATGQAEDLAEVSVDSPGPSERETLPRKETVME 355
++E+ + H ++ ++ + KK Q AT + E+ + + + RE L R + E
Sbjct: 152 EMELDLHQKH--VVNSWEMQKEEKKQQEATAEQEN--KRYENEYERARREALERMKAEEE 207
Query: 356 ESQ-QEPMKEEQLFSPLPPSPMAMI------RDSGAIAAGHQPLSTMTVRSRVADVFGSK 408
Q ++ ++ E L + + + ++ + L + + + F K
Sbjct: 208 RRQLEDKLQAEALLQQMEELKLKEVEATKLKKEQENLLKQRWELERLEEERKQMEAFRQK 267
Query: 409 DTESLEPVLLPLVDRRFPKKWERPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESS 468
L L + + ++ ++ + E L + + +K + H +++ + +
Sbjct: 268 --AELGRFLRHQYNAQLSRRTQQ-IQEELEADRRILQALLEKEDESQRLHLARREQVMAD 324
Query: 469 RQVTSESQEEPWEEEFGREMRRQLWLEEE--EMWQQRQKKWALLEQEHQEKLRQWNLEDL 526
++ EE + E RE Q+ L EE EMW++R+ +WA E+ +++L L
Sbjct: 325 VAWMKQAIEEQLQLERAREAELQMLLREEAKEMWEKREAEWA-RERSARDRLMSEVLTGR 383
Query: 527 AREQQRRWVQLEKEQESPRREPEQLGEDVE------RRIFTPTSRWRDLEKAELSLVPAP 580
++ Q + Q + QE + EQL ++E RR + + + K EL A
Sbjct: 384 QQQIQEKIEQNRRAQEESLKHREQLIRNLEEVRELARREKEESEKLKSARKQELEAQVAE 443
Query: 581 SRTQS--AHQSRRPHLPMSPSTQQ--PALGKQRPMSSVEFTYRPR 621
R Q+ A Q + +Q AL +Q + E YRP+
Sbjct: 444 RRLQAWEADQQEEEEEEEARRVEQLSDALLQQEAETMAEQGYRPK 488
Score = 33.5 bits (75), Expect = 0.91
Identities = 55/277 (19%), Positives = 111/277 (40%), Gaps = 9/277 (3%)
Query: 459 CSKQLSLESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKL 518
CS + + SS+ S E+ E RR L E++ Q Q++ LL +E +E
Sbjct: 47 CSSKQAEWSSKTSYQRSMHAYQREKMKEEKRRSLEARREKLRQLMQEEQDLLARELEELR 106
Query: 519 RQWNLEDLAREQQRRWVQLEKEQESPRREPEQLGEDVERRIFTPTSRWRDLEKAELSLVP 578
NL++ +Q ++ KE++ + L E ++ P R +L+ + +V
Sbjct: 107 LSMNLQERRIREQHGKLKSAKEEQRKLIAEQLLYEHWKKN--NPKLREMELDLHQKHVVN 164
Query: 579 APSRTQSAHQSRRPHLPMSPSTQQPALGKQRPMSSVEFTYRPRTRRVPTKPKKSASF-PV 637
+ + + + + + R + R++ K + A +
Sbjct: 165 SWEMQKEEKKQQEATAEQENKRYENEYERARREALERMKAEEERRQLEDKLQAEALLQQM 224
Query: 638 TGTSIRRLTWPSLQISPANIKKKVYHMD-MEAQRKNLQLLSEESELR--LPHYLRSKALE 694
++ + L+ N+ K+ + ++ +E +RK ++ +++EL L H ++
Sbjct: 225 EELKLKEVEATKLKKEQENLLKQRWELERLEEERKQMEAFRQKAELGRFLRHQYNAQLSR 284
Query: 695 LTTTTM-ELGALR--LQYLCHKYIFYRRLQSLRQEAI 728
T EL A R LQ L K +RL R+E +
Sbjct: 285 RTQQIQEELEADRRILQALLEKEDESQRLHLARREQV 321
Score = 31.6 bits (70), Expect = 3.4
Identities = 47/194 (24%), Positives = 81/194 (41%), Gaps = 28/194 (14%)
Query: 193 LSPEQMLQDQHTMNTKASEVTSMLQELLDSTMFSKGEVRAI----RYMATVVENLNKALI 248
L E +LQ + K E T + +E ++ + + E+ + + M +
Sbjct: 215 LQAEALLQQMEELKLKEVEATKLKKEQ-ENLLKQRWELERLEEERKQMEAFRQKAELGRF 273
Query: 249 LQHKEN-----------RSLETKYRHLQMQATKELSSQRLHF---QQFMEVLESRRDALL 294
L+H+ N LE R LQ KE SQRLH +Q M + + A+
Sbjct: 274 LRHQYNAQLSRRTQQIQEELEADRRILQALLEKEDESQRLHLARREQVMADVAWMKQAIE 333
Query: 295 KQVEILGGRYHDL--LLMKQALEFQLKKAQNATGQAEDLAEVSVDSPGPSERETLPRKET 352
+Q+++ R +L LL ++A E K+ +AE E S SE T R++
Sbjct: 334 EQLQLERAREAELQMLLREEAKEMWEKR------EAEWARERSARDRLMSEVLT-GRQQQ 386
Query: 353 VMEESQQEPMKEEQ 366
+ E+ +Q +E+
Sbjct: 387 IQEKIEQNRRAQEE 400
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 45.1 bits (105), Expect = 3e-04
Identities = 35/103 (33%), Positives = 52/103 (50%), Gaps = 11/103 (10%)
Query: 461 KQLSLESSRQVTSESQEEPWEEEFGR-----EMRRQLWLEEEEMWQQRQKKWALLEQEHQ 515
+Q LE VT E ++ E F R E RRQ LE++ Q+R + EQE +
Sbjct: 338 EQQQLEKKLPVTFEDKKR---ENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERK 394
Query: 516 EKLRQWNLEDLAREQQRRWVQLEKEQESPRREPEQLGEDVERR 558
E+ RQ E + Q QLEK++E R+ E+ +++ERR
Sbjct: 395 ERERQ---EQERKRQLELEKQLEKQRELERQREEERRKEIERR 434
Score = 35.8 bits (81), Expect = 0.18
Identities = 68/340 (20%), Positives = 133/340 (39%), Gaps = 60/340 (17%)
Query: 463 LSLESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWN 522
+S+ SS V EEP E+ +++ ++L + E+ ++ ++ L EK RQ
Sbjct: 317 ISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFERGNL----ELEKRRQAL 372
Query: 523 LEDLAREQQRRWVQLEK-EQESPRREPEQLGEDVERRIFTPTSRWRDLEKAELSLVPAPS 581
LE R++Q R QLE+ EQE RE ++ + + + R+LE+
Sbjct: 373 LEQ-QRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELER---------- 421
Query: 582 RTQSAHQSRRPHLPMSPSTQQPALGKQRPMSSVEFTYRPRTRRVPTKPKKSASFPVTGTS 641
+ RR + + ++ L +QR +E+ R + + K+ V
Sbjct: 422 ---QREEERRKEIERREAAKR-ELERQR---QLEWERNRRQELLNQRNKEQEDIVVLKAK 474
Query: 642 IRRLTWPSLQISPANIKKKVYHMDME-------AQRKNLQLLSEESELRLPHYLRSKALE 694
+ L ++ N KK ++ QR+ ++ ++ ELR+ + +
Sbjct: 475 KKTL---EFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQ-Q 530
Query: 695 LTTTTMELGALRLQYLCHKYIFYRRLQSLRQEAINHVQIMK------------------- 735
L + LG L + K I +L+ ++Q +++ ++
Sbjct: 531 LQESQQMLGRL----IPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQL 586
Query: 736 ---ETEASYKAQNLYIFLENIDRLQSLRLQAWTDKQKGLE 772
E E K Q + IF + L+ + + KQK +E
Sbjct: 587 DEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSME 626
Score = 33.1 bits (74), Expect = 1.2
Identities = 86/444 (19%), Positives = 158/444 (35%), Gaps = 72/444 (16%)
Query: 180 GRSPQTSPSHPQPLSPEQMLQDQHTMNTKASEVTSMLQELLDSTMFSKGEVRAIRYMATV 239
G S +S S Q L E +L+D+ K VT E F +G + + +
Sbjct: 316 GISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTF---EDKKRENFERGNLELEKRRQAL 372
Query: 240 VENLNKAL--------ILQHKENRSLETKYRHLQMQATKELSSQR--------------- 276
+E K Q ++ R + + R Q++ K+L QR
Sbjct: 373 LEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIE 432
Query: 277 --------LHFQQFMEVLESRRDALLKQVEILGGRYHDLLLMK---QALEFQLK----KA 321
L Q+ +E +RR LL Q D++++K + LEF+L+ K
Sbjct: 433 RREAAKRELERQRQLEWERNRRQELLNQ---RNKEQEDIVVLKAKKKTLEFELEALNDKK 489
Query: 322 QNATGQAEDLAEVSVDSPGPSERETLPRKETVMEES--QQEPMKEEQLFSPLPPSPMAMI 379
G+ +D+ E R+ + E + QQ+ + +Q+ L P +
Sbjct: 490 HQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILN 549
Query: 380 RDSGAIAAGHQPLSTMTVRSRVADVFGSKDTESLEPVLLPLVDRRFPKKWERPVAESLGH 439
+ ++ R + E L +D + E+ L
Sbjct: 550 DQLKQVQQNSLHRDSLVTLKRALEA-----KELARQHLRDQLD-----EVEKETRSKLQE 599
Query: 440 KDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEM 499
D + + K KQ S+E+ R E + + E E +E ++ E ++
Sbjct: 600 IDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEAQRRAQERDKQ 659
Query: 500 WQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKEQESPRREPEQLG------- 552
W + ++ E EHQ + E L RE+ + + + E++ + ++LG
Sbjct: 660 WLEHVQQ----EDEHQRPRKLHEEEKLKREESVK--KKDGEEKGKQEAQDKLGRLFHQHQ 713
Query: 553 EDVERRIFTPTSRWRDLEKAELSL 576
E + + P W EK L++
Sbjct: 714 EPAKPAVQAP---WSTAEKGPLTI 734
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 45.1 bits (105), Expect = 3e-04
Identities = 35/103 (33%), Positives = 52/103 (50%), Gaps = 11/103 (10%)
Query: 461 KQLSLESSRQVTSESQEEPWEEEFGR-----EMRRQLWLEEEEMWQQRQKKWALLEQEHQ 515
+Q LE VT E ++ E F R E RRQ LE++ Q+R + EQE +
Sbjct: 338 EQQQLEKKLPVTFEDKKR---ENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERK 394
Query: 516 EKLRQWNLEDLAREQQRRWVQLEKEQESPRREPEQLGEDVERR 558
E+ RQ E + Q QLEK++E R+ E+ +++ERR
Sbjct: 395 ERERQ---EQERKRQLELEKQLEKQRELERQREEERRKEIERR 434
Score = 35.8 bits (81), Expect = 0.18
Identities = 68/340 (20%), Positives = 133/340 (39%), Gaps = 60/340 (17%)
Query: 463 LSLESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLRQWN 522
+S+ SS V EEP E+ +++ ++L + E+ ++ ++ L EK RQ
Sbjct: 317 ISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFERGNL----ELEKRRQAL 372
Query: 523 LEDLAREQQRRWVQLEK-EQESPRREPEQLGEDVERRIFTPTSRWRDLEKAELSLVPAPS 581
LE R++Q R QLE+ EQE RE ++ + + + R+LE+
Sbjct: 373 LEQ-QRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELER---------- 421
Query: 582 RTQSAHQSRRPHLPMSPSTQQPALGKQRPMSSVEFTYRPRTRRVPTKPKKSASFPVTGTS 641
+ RR + + ++ L +QR +E+ R + + K+ V
Sbjct: 422 ---QREEERRKEIERREAAKR-ELERQR---QLEWERNRRQELLNQRNKEQEDIVVLKAK 474
Query: 642 IRRLTWPSLQISPANIKKKVYHMDME-------AQRKNLQLLSEESELRLPHYLRSKALE 694
+ L ++ N KK ++ QR+ ++ ++ ELR+ + +
Sbjct: 475 KKTL---EFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQ-Q 530
Query: 695 LTTTTMELGALRLQYLCHKYIFYRRLQSLRQEAINHVQIMK------------------- 735
L + LG L + K I +L+ ++Q +++ ++
Sbjct: 531 LQESQQMLGRL----IPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQL 586
Query: 736 ---ETEASYKAQNLYIFLENIDRLQSLRLQAWTDKQKGLE 772
E E K Q + IF + L+ + + KQK +E
Sbjct: 587 DEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSME 626
Score = 33.1 bits (74), Expect = 1.2
Identities = 86/444 (19%), Positives = 158/444 (35%), Gaps = 72/444 (16%)
Query: 180 GRSPQTSPSHPQPLSPEQMLQDQHTMNTKASEVTSMLQELLDSTMFSKGEVRAIRYMATV 239
G S +S S Q L E +L+D+ K VT E F +G + + +
Sbjct: 316 GISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTF---EDKKRENFERGNLELEKRRQAL 372
Query: 240 VENLNKAL--------ILQHKENRSLETKYRHLQMQATKELSSQR--------------- 276
+E K Q ++ R + + R Q++ K+L QR
Sbjct: 373 LEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIE 432
Query: 277 --------LHFQQFMEVLESRRDALLKQVEILGGRYHDLLLMK---QALEFQLK----KA 321
L Q+ +E +RR LL Q D++++K + LEF+L+ K
Sbjct: 433 RREAAKRELERQRQLEWERNRRQELLNQ---RNKEQEDIVVLKAKKKTLEFELEALNDKK 489
Query: 322 QNATGQAEDLAEVSVDSPGPSERETLPRKETVMEES--QQEPMKEEQLFSPLPPSPMAMI 379
G+ +D+ E R+ + E + QQ+ + +Q+ L P +
Sbjct: 490 HQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILN 549
Query: 380 RDSGAIAAGHQPLSTMTVRSRVADVFGSKDTESLEPVLLPLVDRRFPKKWERPVAESLGH 439
+ ++ R + E L +D + E+ L
Sbjct: 550 DQLKQVQQNSLHRDSLVTLKRALEA-----KELARQHLRDQLD-----EVEKETRSKLQE 599
Query: 440 KDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEM 499
D + + K KQ S+E+ R E + + E E +E ++ E ++
Sbjct: 600 IDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEAQRRAQERDKQ 659
Query: 500 WQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKEQESPRREPEQLG------- 552
W + ++ E EHQ + E L RE+ + + + E++ + ++LG
Sbjct: 660 WLEHVQQ----EDEHQRPRKLHEEEKLKREESVK--KKDGEEKGKQEAQDKLGRLFHQHQ 713
Query: 553 EDVERRIFTPTSRWRDLEKAELSL 576
E + + P W EK L++
Sbjct: 714 EPAKPAVQAP---WSTAEKGPLTI 734
>gi|223005859 WD repeat domain 67 isoform 1 [Homo sapiens]
Length = 1066
Score = 44.7 bits (104), Expect = 4e-04
Identities = 35/109 (32%), Positives = 62/109 (56%), Gaps = 14/109 (12%)
Query: 476 QEEPWEEEF-----GREMRRQLWLEEEE-MWQQRQKKWALLEQEHQEKLRQWNLEDLARE 529
++E W ++ E RR++ L+EEE M QQRQ+ L + + K+++ +L+D AR
Sbjct: 722 EDEAWYQKQELLRKAEETRREMLLQEEEKMIQQRQR---LAAVKRELKVKEMHLQDAAR- 777
Query: 530 QQRRWVQLEKEQESP--RREPEQLGEDVERRIFTPTSRWRDLEKAELSL 576
RR+++L+++Q+ RR +++G V R + RDLE +L L
Sbjct: 778 --RRFLKLQQDQQEMELRRLDDEIGRKVYMRDREIAATARDLEMRQLEL 824
>gi|7661936 scaffold attachment factor B2 [Homo sapiens]
Length = 953
Score = 44.7 bits (104), Expect = 4e-04
Identities = 64/275 (23%), Positives = 116/275 (42%), Gaps = 31/275 (11%)
Query: 315 EFQLKKAQNATGQAEDLAEVSVDSPGPSERETLPRKETVMEESQQEPMKEEQLFSPLPPS 374
E ++KK + ++ E+ ++ + E + +KE E+ ++ KEE+ L P
Sbjct: 497 ECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKE---EKKPEDIKKEEKDQDELKPG 553
Query: 375 PMAMIRDSGAIAAGHQPLSTMTVRSRVADVFGSKDTESLEPVLLPLVDRRFPKKWERPVA 434
P R + + + G + M +S+ V K T + DR+ K +R +
Sbjct: 554 PTNRSRVTKSGSRGMERTVVMD-KSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRDIL 612
Query: 435 ESLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWEEEFGREMRRQLWL 494
K++ + + ++ +I+ E R+ +E+ E R+ + +L
Sbjct: 613 SFDKIKEQRERERQRQREREIR-------ETERRREREQREREQRLEAFHERKEKARLQR 665
Query: 495 EEEEMWQQRQKKWALLEQEHQEKLRQWNLEDLAREQQRRWVQLEKEQESP-------RRE 547
E ++ QRQ+ LE+E E+ E L RE+ R + KEQE RR+
Sbjct: 666 ERLQLECQRQR----LERERMER------ERLERERMRVERERRKEQERIHREREELRRQ 715
Query: 548 PEQLGEDVERRIFTPTSRWRDLEKAELSLVPAPSR 582
EQL + ERR P R DL++ + + P R
Sbjct: 716 QEQLRYEQERR---PGRRPYDLDRRDDAYWPEGKR 747
>gi|31563330 A-kinase anchor protein 13 isoform 1 [Homo sapiens]
Length = 2817
Score = 43.9 bits (102), Expect = 7e-04
Identities = 57/198 (28%), Positives = 80/198 (40%), Gaps = 37/198 (18%)
Query: 461 KQLSLESSRQVTSESQ-------------EEPWEEEFGREMRRQ--LWLEEEEMWQQRQK 505
KQ SLE RQ + Q E WE RE+R + L + EE QQ Q+
Sbjct: 2577 KQRSLEKQRQDLANLQKQQAQYLEEKRRREREWEAR-ERELREREALLAQREEEVQQGQQ 2635
Query: 506 KWALLEQEHQEK--LRQWNLEDLAREQQRRWVQLEKEQESPRREPEQLGEDVERRIFTPT 563
+E Q+K Q++LE L Q+ QLE+EQE RRE E+L + R
Sbjct: 2636 DLEKEREELQQKKGTYQYDLERLRAAQK----QLEREQEQLRREAERLSQRQTERDLCQV 2691
Query: 564 SRWRDLEKAELSLVPAPSRTQSAHQSRRPHLPMSPSTQQPALGKQRPMSSVEFTYRPRTR 623
S L+ PS S P P SPS P++ K + S E + P+
Sbjct: 2692 SH------PHTKLMRIPSFFPS------PEEPPSPSA--PSIAKSGSLDS-ELSVSPKRN 2736
Query: 624 RVPTKPKKSASFPVTGTS 641
+ K F + ++
Sbjct: 2737 SISRTHKDKGPFHILSST 2754
>gi|21493031 A-kinase anchor protein 13 isoform 3 [Homo sapiens]
Length = 1058
Score = 43.9 bits (102), Expect = 7e-04
Identities = 57/198 (28%), Positives = 80/198 (40%), Gaps = 37/198 (18%)
Query: 461 KQLSLESSRQVTSESQ-------------EEPWEEEFGREMRRQ--LWLEEEEMWQQRQK 505
KQ SLE RQ + Q E WE RE+R + L + EE QQ Q+
Sbjct: 818 KQRSLEKQRQDLANLQKQQAQYLEEKRRREREWEAR-ERELREREALLAQREEEVQQGQQ 876
Query: 506 KWALLEQEHQEK--LRQWNLEDLAREQQRRWVQLEKEQESPRREPEQLGEDVERRIFTPT 563
+E Q+K Q++LE L Q+ QLE+EQE RRE E+L + R
Sbjct: 877 DLEKEREELQQKKGTYQYDLERLRAAQK----QLEREQEQLRREAERLSQRQTERDLCQV 932
Query: 564 SRWRDLEKAELSLVPAPSRTQSAHQSRRPHLPMSPSTQQPALGKQRPMSSVEFTYRPRTR 623
S L+ PS S P P SPS P++ K + S E + P+
Sbjct: 933 SH------PHTKLMRIPSFFPS------PEEPPSPSA--PSIAKSGSLDS-ELSVSPKRN 977
Query: 624 RVPTKPKKSASFPVTGTS 641
+ K F + ++
Sbjct: 978 SISRTHKDKGPFHILSST 995
>gi|21493029 A-kinase anchor protein 13 isoform 2 [Homo sapiens]
Length = 2813
Score = 43.9 bits (102), Expect = 7e-04
Identities = 57/198 (28%), Positives = 80/198 (40%), Gaps = 37/198 (18%)
Query: 461 KQLSLESSRQVTSESQ-------------EEPWEEEFGREMRRQ--LWLEEEEMWQQRQK 505
KQ SLE RQ + Q E WE RE+R + L + EE QQ Q+
Sbjct: 2573 KQRSLEKQRQDLANLQKQQAQYLEEKRRREREWEAR-ERELREREALLAQREEEVQQGQQ 2631
Query: 506 KWALLEQEHQEK--LRQWNLEDLAREQQRRWVQLEKEQESPRREPEQLGEDVERRIFTPT 563
+E Q+K Q++LE L Q+ QLE+EQE RRE E+L + R
Sbjct: 2632 DLEKEREELQQKKGTYQYDLERLRAAQK----QLEREQEQLRREAERLSQRQTERDLCQV 2687
Query: 564 SRWRDLEKAELSLVPAPSRTQSAHQSRRPHLPMSPSTQQPALGKQRPMSSVEFTYRPRTR 623
S L+ PS S P P SPS P++ K + S E + P+
Sbjct: 2688 SH------PHTKLMRIPSFFPS------PEEPPSPSA--PSIAKSGSLDS-ELSVSPKRN 2732
Query: 624 RVPTKPKKSASFPVTGTS 641
+ K F + ++
Sbjct: 2733 SISRTHKDKGPFHILSST 2750
>gi|94721321 coiled-coil domain containing 11 [Homo sapiens]
Length = 514
Score = 43.9 bits (102), Expect = 7e-04
Identities = 61/270 (22%), Positives = 123/270 (45%), Gaps = 24/270 (8%)
Query: 284 EVLESRRDALLKQVEILGGRYHDLLLMKQALEFQLKKAQNATGQAEDLAEVSVDSPGPSE 343
E++E+ R L Q+ + + L+K+ E +L ++ NA + E+ ++ E
Sbjct: 225 ELMENTRLGLNAQITSIKAQRQATQLLKEE-EARLVESNNAQIKHENEQDMLKKQKAKQE 283
Query: 344 RETLPRK--ETVMEESQQEPMKEEQLFSPLPPSPMAMIRDSGAIAAGHQPLSTMTVRSRV 401
T+ +K + +E QQE E+ L L + +++ Q M ++
Sbjct: 284 TRTILQKALQERIEHIQQEYRDEQDLNMKLVQRALQDLQEEAD--KKKQKREDMIREQKI 341
Query: 402 ADVFGSKDTESLEPVLLPLVDRRFPKKWERPVAESLGHKDKDQE-DYFQKGGLQIKFHCS 460
+ ++ E + ++ F + E A+ L KDK+ + + L + C+
Sbjct: 342 YHKYLAQRREEEKAQ-----EKEFDRILEEDKAKKLAEKDKELRLEKEARRQLVDEVMCT 396
Query: 461 KQLSLESSRQVTSESQEE-PWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKLR 519
++L ++ Q ++ QEE E++ E ++L EE+E + +RQ+ L QE++++L+
Sbjct: 397 RKLQVQEKLQREAKEQEERAMEQKHINESLKELNCEEKENFARRQR----LAQEYRKQLQ 452
Query: 520 QWNLEDLAREQQRRWVQLEKEQESPRREPE 549
+A +QQ + E E+E RRE E
Sbjct: 453 M----QIAYQQQSQ----EAEKEEKRREFE 474
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 43.5 bits (101), Expect = 9e-04
Identities = 115/522 (22%), Positives = 214/522 (40%), Gaps = 106/522 (20%)
Query: 114 EIGPRKSE----EEAAALDEW------IEVTEKVLP---LSLIATKRGIESLTALCST-- 158
E+GP + E EE A+ + TE V P LS A K E++ +
Sbjct: 548 ELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQ 607
Query: 159 --LIEGQKKRSQVSKRTFWQGWQGRSPQTSPSHPQPLSP------EQMLQDQHTMNTKAS 210
L+E ++++ Q + Q + + Q LS + + +++ M + S
Sbjct: 608 RHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEES 667
Query: 211 EVTSMLQ-ELLDSTMFSKGEVRAIRYMATVVENLNKALILQHKENR-SLETKYRHLQMQA 268
+ S L+ ++ ST + ++RA + + ++ L + L Q K R SLE K R + Q
Sbjct: 668 QRLSWLRAQVQSSTQADEDQIRAEQEAS--LQKLREELESQQKAERASLEQKNRQMLEQL 725
Query: 269 TKELSSQRLHFQQFMEVLESRRDALLKQVEILGGRYHDLLLMKQALEFQLKKAQNATGQA 328
+E+ + Q L + ++ L+Q +++ LE + K+A AT +
Sbjct: 726 KEEIEASEKSEQA---ALNAAKEKALQQ-------------LREQLEGERKEAV-ATLEK 768
Query: 329 EDLAEVS--VDSPGPSERETLPRKETVMEESQQEPMKEEQLFSPLPPSPMAMIRDSGAIA 386
E AE+ S RE + + ++E+QQ+ +E QL L + + S +A
Sbjct: 769 EHSAELERLCSSLEAKHREVVSSLQKKIQEAQQK--EEAQLQKCLGQVEHRVHQKSYHVA 826
Query: 387 AGHQPLSTMTVRSRVADVFGSKDTESLEPVLLPLVDRRFPK-KWERPVAESLGHKDKDQE 445
LS++ +R + +V G + RR K K E + + + E
Sbjct: 827 GYEHELSSL-LREKRQEVEGEHE-------------RRLDKMKEEHQQVMAKAREQYEAE 872
Query: 446 DYFQKGGLQIKFHCSKQLSLESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEMWQQRQK 505
+ Q+ ++ H + +L E R R+L E + Q++ K
Sbjct: 873 ERKQRA--ELLGHLTGEL------------------ERLQRAHEREL----ETVRQEQHK 908
Query: 506 KWALLEQEHQEKLR-----QWNLEDLAREQQRRWVQLEKEQESPRREPEQLGEDVERRIF 560
+ L + H+E+ R + +LE A++ + R LE ++E+ RRE +QL DV+R++
Sbjct: 909 RLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQL-LDVQRQV- 966
Query: 561 TPTSRWRDLEKAELSLVPAPSRTQSAHQSRRPHLPMSPSTQQ 602
L A + Q ++++ H + S QQ
Sbjct: 967 ------------ALKSEEATATHQQLEEAQKEHTHLLQSNQQ 996
Score = 37.7 bits (86), Expect = 0.048
Identities = 103/479 (21%), Positives = 186/479 (38%), Gaps = 76/479 (15%)
Query: 356 ESQQEPMKEEQLFSPLPPSPMAMIRDSGAIAAGHQPLSTMTVRS--RVADVFGSKDTESL 413
+S+Q EE+L PLP A ++A +P + + A+ G SL
Sbjct: 460 QSKQSKGLEERLSPPLPHEERAQ-SPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASL 518
Query: 414 EPVLLPLVDRRFPK--------KWERPVAESLGHKDKDQEDYFQKGGLQIKFHCSKQLSL 465
+ L L + P K + AE LG ++ ED +K + S ++
Sbjct: 519 S-LQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRS 577
Query: 466 -------ESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKL 518
E + ++ EE + ++ R L ++E+M QQ ++K E+E +L
Sbjct: 578 TEPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKM-QQLREKLCQEEEEEILRL 636
Query: 519 RQWNLEDLAREQQRRWVQLEKEQESPRREPEQLGEDVERRIFTPTSRWRDLEKA--ELSL 576
Q + L+ ++R +E+E+ R E Q + ++ + T D +A E SL
Sbjct: 637 HQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASL 696
Query: 577 VPAPSRTQSAHQSRRPHLPM---------------SPSTQQPAL--GKQRPMSSV-EFTY 618
+S ++ R L S ++Q AL K++ + + E
Sbjct: 697 QKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLE 756
Query: 619 RPRTRRVPTKPKKSASFPVTGTSIRRLTWPSLQISPANIKKKVYHMDMEAQRKNLQLLSE 678
R V T K+ ++ + RL SL+ + + EAQ+K E
Sbjct: 757 GERKEAVATLEKEHSA------ELERLC-SSLEAKHREVVSSLQKKIQEAQQK------E 803
Query: 679 ESEL-----RLPHYLRSKALELTTTTMELGA-LRLQYLCHKYIFYRRLQSLRQEAINHVQ 732
E++L ++ H + K+ + EL + LR + + RRL +++E H Q
Sbjct: 804 EAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEE---HQQ 860
Query: 733 IMKETEASYKAQ----------NLYIFLENIDRLQSLRLQAWTDKQ----KGLEEKHRE 777
+M + Y+A+ +L LE + R L+ +Q + L +HRE
Sbjct: 861 VMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHRE 919
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 43.1 bits (100), Expect = 0.001
Identities = 59/279 (21%), Positives = 111/279 (39%), Gaps = 39/279 (13%)
Query: 351 ETVMEESQQEPMKEEQLFSPLPPSPMAMIRDSGAIAAGHQPLSTMTVRSRVADVFGSKDT 410
E ES+ E + E + S LPP + + + H P + ++ D K
Sbjct: 163 EEASAESEDEMIHPEGVASLLPPDFQSSLERPELELSRHSPRKSSSISEEKGDSDDEKPR 222
Query: 411 ESLEPVLLPLVDRRFPKKWERPVAE-SLGHKDKDQEDYFQKGGLQIKFHCSKQLSLESSR 469
+ +RR + + A+ S G + ++E+ + ++ + L E
Sbjct: 223 KG---------ERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEE 273
Query: 470 QVTSESQEEPWEEEF---GREMRRQLWLEE-------------EEMWQQRQK----KWAL 509
+ E +E+ EEE G++ R L+E EEM +R K + +
Sbjct: 274 EEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEV 333
Query: 510 LEQ-----EHQEKLRQWNLEDLAREQQRRWVQLEKEQESPRREPEQLGEDVERRIFTPTS 564
LE+ QE+ R+ LAR+QQ + ++ E RE + + ++ + +P+
Sbjct: 334 LERGGRFTRSQEEARK---SHLARQQQEKEMKTTSPLEEEEREIKS-SQGLKEKSKSPSP 389
Query: 565 RWRDLEKAELSLVPAPSRTQSAHQSRRPHLPMSPSTQQP 603
++ + SLV P +T S ++ P L S+ P
Sbjct: 390 PRLTEDRKKASLVALPEQTASEEETPPPLLTKEASSPPP 428
Score = 31.6 bits (70), Expect = 3.4
Identities = 30/110 (27%), Positives = 55/110 (50%), Gaps = 5/110 (4%)
Query: 459 CSKQLSLESSRQVTSESQEEPWEEEFGREMRRQLWLEEEEMWQQRQKKWALLEQEHQEKL 518
C L L S+ V E++ +E RE RR+ EEE+ ++++ + Q +EK
Sbjct: 1223 CIYWLPLTDSQIVQKEAERAERAKE--REKRRKEQEEEEQKEREKEAERERNRQLEREKR 1280
Query: 519 RQWNLE-DLAREQQRRWVQLEKEQESPRREPEQLGEDVERRIFTPTSRWR 567
R+ + E D RE++R + +++++ R + G + +RR SR R
Sbjct: 1281 REHSRERDRERERERERDRGDRDRD--RERDRERGRERDRRDTKRHSRSR 1328
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.129 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,000,689
Number of Sequences: 37866
Number of extensions: 1703644
Number of successful extensions: 13211
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 89
Number of HSP's successfully gapped in prelim test: 384
Number of HSP's that attempted gapping in prelim test: 9262
Number of HSP's gapped (non-prelim): 2183
length of query: 893
length of database: 18,247,518
effective HSP length: 111
effective length of query: 782
effective length of database: 14,044,392
effective search space: 10982714544
effective search space used: 10982714544
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.