Search of human proteins with 14149704

Search of human proteins with 14149704

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14149704 oxysterol-binding protein-like protein 3 isoform a
[Homo sapiens]
         (887 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14149704 oxysterol-binding protein-like protein 3 isoform a [...  1803   0.0  
gi|21735580 oxysterol-binding protein-like protein 3 isoform b [...  1724   0.0  
gi|21735582 oxysterol-binding protein-like protein 3 isoform c [...  1719   0.0  
gi|21735584 oxysterol-binding protein-like protein 3 isoform d [...  1639   0.0  
gi|14210532 oxysterol-binding protein-like protein 6 isoform a [...  1047   0.0  
gi|22035612 oxysterol-binding protein-like protein 6 isoform b [...  1033   0.0  
gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens]   808   0.0  
gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo sa...   296   4e-80
gi|21450853 oxysterol-binding protein-like protein 2 isoform 2 [...   293   4e-79
gi|4505531 oxysterol binding protein [Homo sapiens]                   293   5e-79
gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo sa...   291   1e-78
gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [H...   289   9e-78
gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens]      266   8e-71
gi|14149740 oxysterol-binding protein-like protein 5 isoform a [...   106   8e-23
gi|221136766 oxysterol-binding protein-like protein 5 isoform b ...   106   8e-23
gi|22035609 oxysterol-binding protein-like protein 5 isoform b [...   106   8e-23
gi|51243032 oxysterol-binding protein-like protein 8 isoform b [...    90   8e-18
gi|18079218 oxysterol-binding protein-like protein 8 isoform a [...    90   8e-18
gi|20070331 oxysterol binding protein-like 9 isoform e [Homo sap...    90   1e-17
gi|22547176 oxysterol binding protein-like 9 isoform f [Homo sap...    90   1e-17
gi|22547173 oxysterol binding protein-like 9 isoform d [Homo sap...    90   1e-17
gi|22547171 oxysterol binding protein-like 9 isoform c [Homo sap...    90   1e-17
gi|22547169 oxysterol binding protein-like 9 isoform b [Homo sap...    90   1e-17
gi|22547167 oxysterol binding protein-like 9 isoform a [Homo sap...    90   1e-17
gi|22547165 oxysterol binding protein-like 9 isoform a [Homo sap...    90   1e-17
gi|19923812 oxysterol-binding protein-like protein 10 [Homo sapi...    89   1e-17
gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]           75   2e-13
gi|217416392 pleckstrin homology domain containing, family H (wi...    57   6e-08
gi|55741447 pleckstrin homology domain containing, family H (wit...    45   2e-04
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa...    44   5e-04

>gi|14149704 oxysterol-binding protein-like protein 3 isoform a
           [Homo sapiens]
          Length = 887

 Score = 1803 bits (4671), Expect = 0.0
 Identities = 887/887 (100%), Positives = 887/887 (100%)

Query: 1   MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60
           MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK
Sbjct: 1   MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60

Query: 61  KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120
           KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE
Sbjct: 61  KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120

Query: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180
           EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS
Sbjct: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180

Query: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240
           SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL
Sbjct: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240

Query: 241 QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR 300
           QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR
Sbjct: 241 QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR 300

Query: 301 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK 360
           LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK
Sbjct: 301 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK 360

Query: 361 LKQLMEQDASSSPSAQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNL 420
           LKQLMEQDASSSPSAQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNL
Sbjct: 361 LKQLMEQDASSSPSAQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNL 420

Query: 421 AEENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD 480
           AEENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD
Sbjct: 421 AEENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD 480

Query: 481 NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL 540
           NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL
Sbjct: 481 NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL 540

Query: 541 SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA 600
           SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA
Sbjct: 541 SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA 600

Query: 601 GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK 660
           GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK
Sbjct: 601 GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK 660

Query: 661 SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV 720
           SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV
Sbjct: 661 SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV 720

Query: 721 NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE 780
           NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE
Sbjct: 721 NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE 780

Query: 781 QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR 840
           QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR
Sbjct: 781 QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR 840

Query: 841 RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW 887
           RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW
Sbjct: 841 RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW 887


>gi|21735580 oxysterol-binding protein-like protein 3 isoform b
           [Homo sapiens]
          Length = 856

 Score = 1724 bits (4465), Expect = 0.0
 Identities = 856/887 (96%), Positives = 856/887 (96%), Gaps = 31/887 (3%)

Query: 1   MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60
           MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK
Sbjct: 1   MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60

Query: 61  KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120
           KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE
Sbjct: 61  KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120

Query: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180
           EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS
Sbjct: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180

Query: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240
           SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL
Sbjct: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240

Query: 241 QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR 300
           QSMDVLHRTYSAPAINAIQ                               VPKPFSGPVR
Sbjct: 241 QSMDVLHRTYSAPAINAIQ-------------------------------VPKPFSGPVR 269

Query: 301 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK 360
           LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK
Sbjct: 270 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK 329

Query: 361 LKQLMEQDASSSPSAQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNL 420
           LKQLMEQDASSSPSAQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNL
Sbjct: 330 LKQLMEQDASSSPSAQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNL 389

Query: 421 AEENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD 480
           AEENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD
Sbjct: 390 AEENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD 449

Query: 481 NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL 540
           NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL
Sbjct: 450 NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL 509

Query: 541 SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA 600
           SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA
Sbjct: 510 SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA 569

Query: 601 GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK 660
           GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK
Sbjct: 570 GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK 629

Query: 661 SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV 720
           SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV
Sbjct: 630 SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV 689

Query: 721 NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE 780
           NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE
Sbjct: 690 NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE 749

Query: 781 QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR 840
           QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR
Sbjct: 750 QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR 809

Query: 841 RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW 887
           RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW
Sbjct: 810 RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW 856


>gi|21735582 oxysterol-binding protein-like protein 3 isoform c
           [Homo sapiens]
          Length = 851

 Score = 1719 bits (4451), Expect = 0.0
 Identities = 851/887 (95%), Positives = 851/887 (95%), Gaps = 36/887 (4%)

Query: 1   MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60
           MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK
Sbjct: 1   MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60

Query: 61  KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120
           KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE
Sbjct: 61  KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120

Query: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180
           EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS
Sbjct: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180

Query: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240
           SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL
Sbjct: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240

Query: 241 QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR 300
           QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR
Sbjct: 241 QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR 300

Query: 301 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK 360
           LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK
Sbjct: 301 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK 360

Query: 361 LKQLMEQDASSSPSAQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNL 420
           LKQLMEQDASSSPSAQVIGLKNALSS                                  
Sbjct: 361 LKQLMEQDASSSPSAQVIGLKNALSS---------------------------------- 386

Query: 421 AEENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD 480
             ENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD
Sbjct: 387 --ENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD 444

Query: 481 NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL 540
           NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL
Sbjct: 445 NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL 504

Query: 541 SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA 600
           SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA
Sbjct: 505 SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA 564

Query: 601 GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK 660
           GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK
Sbjct: 565 GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK 624

Query: 661 SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV 720
           SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV
Sbjct: 625 SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV 684

Query: 721 NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE 780
           NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE
Sbjct: 685 NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE 744

Query: 781 QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR 840
           QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR
Sbjct: 745 QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR 804

Query: 841 RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW 887
           RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW
Sbjct: 805 RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW 851


>gi|21735584 oxysterol-binding protein-like protein 3 isoform d
           [Homo sapiens]
          Length = 820

 Score = 1639 bits (4245), Expect = 0.0
 Identities = 820/887 (92%), Positives = 820/887 (92%), Gaps = 67/887 (7%)

Query: 1   MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60
           MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK
Sbjct: 1   MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60

Query: 61  KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120
           KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE
Sbjct: 61  KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120

Query: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180
           EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS
Sbjct: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180

Query: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240
           SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL
Sbjct: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240

Query: 241 QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR 300
           QSMDVLHRTYSAPAINAIQ                               VPKPFSGPVR
Sbjct: 241 QSMDVLHRTYSAPAINAIQ-------------------------------VPKPFSGPVR 269

Query: 301 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK 360
           LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK
Sbjct: 270 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK 329

Query: 361 LKQLMEQDASSSPSAQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNL 420
           LKQLMEQDASSSPSAQVIGLKNALSS                                  
Sbjct: 330 LKQLMEQDASSSPSAQVIGLKNALSS---------------------------------- 355

Query: 421 AEENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD 480
             ENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD
Sbjct: 356 --ENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD 413

Query: 481 NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL 540
           NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL
Sbjct: 414 NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL 473

Query: 541 SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA 600
           SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA
Sbjct: 474 SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA 533

Query: 601 GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK 660
           GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK
Sbjct: 534 GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK 593

Query: 661 SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV 720
           SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV
Sbjct: 594 SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV 653

Query: 721 NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE 780
           NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE
Sbjct: 654 NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE 713

Query: 781 QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR 840
           QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR
Sbjct: 714 QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR 773

Query: 841 RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW 887
           RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW
Sbjct: 774 RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW 820


>gi|14210532 oxysterol-binding protein-like protein 6 isoform a
           [Homo sapiens]
          Length = 934

 Score = 1047 bits (2708), Expect = 0.0
 Identities = 527/937 (56%), Positives = 679/937 (72%), Gaps = 53/937 (5%)

Query: 1   MMSDEKNLGVSQKLVSPSR--STSSCSSKQGSRQ-------------------------- 32
           M SDEK +  + K  +P+   ++SS SS++ SRQ                          
Sbjct: 1   MSSDEKGISPAHKTSTPTHRSASSSTSSQRDSRQSIHILERTASSSTEPSVSRQLLEPEP 60

Query: 33  -------DSWEVVEGLRGEMNYTQEPPVQKGFLLKKRKWPLKGWHKRFFYLDKGILKYAK 85
                  DSWE++EGL+      Q+P   +GF+LKKRKWPLKGWHKRFF LD G+LKY+K
Sbjct: 61  VPLSKEADSWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSK 120

Query: 86  SQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKSEEVFDEWVSKLRHHR 145
           +  DI++ K+HG IDVGLSVMS+KK ++ IDLDTEEHIYHLKVKS++ FD WVSKLRHHR
Sbjct: 121 APLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHR 180

Query: 146 MYRQNEIAMFPHEVN-HFFSGSTITDSSSGVFDSISSRKR--SSISKQNLFQTGSNVSFS 202
           +YRQNEI   P + + H F  ++  +SS     S+   K   +S   Q+     +++  +
Sbjct: 181 LYRQNEIVRSPRDASFHIFPSTSTAESSPAANVSVMDGKMQPNSFPWQSPLPCSNSLPAT 240

Query: 203 CG-GETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQSMDVLHRTYSAPAINAIQGG 261
           C  G+++V  WLQ SE+M++C++DLAHC + LVE+S+LLQ++++L RT SAP    +Q  
Sbjct: 241 CTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQAN 300

Query: 262 SFESPKKEKRSHRRWRSRAIGKDAKGTLQVP-KPFSGPVRLHSSNPNL-STLDFGEEKNY 319
             +  KK+KR  RRWR++++ KD K  LQVP      PVRLHSSNPNL + ++F    ++
Sbjct: 301 CVDISKKDKRVTRRWRTKSVSKDTKIQLQVPFSATMSPVRLHSSNPNLCADIEFQTPPSH 360

Query: 320 -SDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREKLKQLM-EQDASSSPSAQV 377
            +D  E+S++++K+QE+ C IA KV+  L+SAFN ++ E+EKLKQ++ EQD S   S Q+
Sbjct: 361 LTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQM 420

Query: 378 IGLKNALSSALAQNTDLKERLRRIHAESLLLD---SPAVAKSGDNLAEENSRDENRALVH 434
             L+ +LS AL QN +L+ RL RIH+ES++ D   S  +  S D   E+     +  L  
Sbjct: 421 ARLRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIH--VSLPLSQ 478

Query: 435 QLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNE 494
           Q++NESRLS+++S+SEFFDAQEVLLS SSSENE SDD+SY+SD+SDN+S DN S   +  
Sbjct: 479 QVANESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNIS 538

Query: 495 RQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLN 554
           RQ L   L  G   ++ RR CLPAPCP +SNI+LWNILRNNIGKDLSKV+MPVELNEPLN
Sbjct: 539 RQILNGELTGGA-FRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLN 597

Query: 555 TLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYE 614
           TLQ LCEE+EYSELLDKA++   P ERMV VAAFA+S Y S+Y+RAGSKPFNPVLGETYE
Sbjct: 598 TLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYE 657

Query: 615 CIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTL 674
           CIREDKGF+FFSEQVSHHPPISACH ES+NFVFWQD+RWKNKFWGKSMEI+P+GT +V L
Sbjct: 658 CIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVML 717

Query: 675 PVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHE 734
           P +GD++ WNKVT+CIHNILSG+RWIEHYGE+ I+N     C CK+ F+K  YW++N +E
Sbjct: 718 PKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNE 777

Query: 735 IEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNE 794
           ++G V D+ GKAV+RLFGKWHE +YCG   S+ C+WR   MP  YE YY FT+FA+ELNE
Sbjct: 778 VQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNE 837

Query: 795 MDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRF 854
           +DP  K LLPPTD RFRPDQRFLEEGNLE A  +KQR+E+LQR RRR +EEN++EH P+F
Sbjct: 838 LDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKF 897

Query: 855 FRKSDD----DSWVSNGTYLELRKDLGFSKLDHPVLW 887
           F+K  D    ++WVSN TY ELRKD GFSK+D PVLW
Sbjct: 898 FKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW 934


>gi|22035612 oxysterol-binding protein-like protein 6 isoform b
           [Homo sapiens]
          Length = 938

 Score = 1033 bits (2672), Expect = 0.0
 Identities = 518/918 (56%), Positives = 665/918 (72%), Gaps = 49/918 (5%)

Query: 10  VSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLKKRKWPLKGW 69
           VS++L+ P     S         DSWE++EGL+      Q+P   +GF+LKKRKWPLKGW
Sbjct: 30  VSRQLLEPEPVPLS------KEADSWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGW 83

Query: 70  HKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVK 129
           HKRFF LD G+LKY+K+  DI++ K+HG IDVGLSVMS+KK ++ IDLDTEEHIYHLKVK
Sbjct: 84  HKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVK 143

Query: 130 SEEVFDEWVSKLRHHRMYRQNEIAMFPHEVN-HFFSGSTITDSSSGVFDSISSRKR--SS 186
           S++ FD WVSKLRHHR+YRQNEI   P + + H F  ++  +SS     S+   K   +S
Sbjct: 144 SQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPSTSTAESSPAANVSVMDGKMQPNS 203

Query: 187 ISKQNLFQTGSNVSFSCG-GETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQSMDV 245
              Q+     +++  +C  G+++V  WLQ SE+M++C++DLAHC + LVE+S+LLQ++++
Sbjct: 204 FPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEI 263

Query: 246 LHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSG-------- 297
           L RT SAP    +Q    +  KK+KR  RRWR++++ KD K  LQ   P  G        
Sbjct: 264 LQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQEGPPAKGQFSTTRRR 323

Query: 298 ------------------PVRLHSSNPNL-STLDFGEEKNY-SDGSETSSEFSKMQEDLC 337
                             PVRLHSSNPNL + ++F    ++ +D  E+S++++K+QE+ C
Sbjct: 324 QRLAAAVATTVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESSTDYTKLQEEFC 383

Query: 338 HIAHKVYFTLRSAFNIMSAEREKLKQLM-EQDASSSPSAQVIGLKNALSSALAQNTDLKE 396
            IA KV+  L+SAFN ++ E+EKLKQ++ EQD S   S Q+  L+ +LS AL QN +L+ 
Sbjct: 384 LIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARLRQSLSQALNQNAELRS 443

Query: 397 RLRRIHAESLLLD---SPAVAKSGDNLAEENSRDENRALVHQLSNESRLSITDSLSEFFD 453
           RL RIH+ES++ D   S  +  S D   E+     +  L  Q++NESRLS+++S+SEFFD
Sbjct: 444 RLNRIHSESIICDQVVSVNIIPSPDEAGEQIH--VSLPLSQQVANESRLSMSESVSEFFD 501

Query: 454 AQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRR 513
           AQEVLLS SSSENE SDD+SY+SD+SDN+S DN S   +  RQ L   L  G   ++ RR
Sbjct: 502 AQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGA-FRNGRR 560

Query: 514 TCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAA 573
            CLPAPCP +SNI+LWNILRNNIGKDLSKV+MPVELNEPLNTLQ LCEE+EYSELLDKA+
Sbjct: 561 ACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKAS 620

Query: 574 QIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHP 633
           +   P ERMV VAAFA+S Y S+Y+RAGSKPFNPVLGETYECIREDKGF+FFSEQVSHHP
Sbjct: 621 ETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHP 680

Query: 634 PISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNI 693
           PISACH ES+NFVFWQD+RWKNKFWGKSMEI+P+GT +V LP +GD++ WNKVT+CIHNI
Sbjct: 681 PISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNI 740

Query: 694 LSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGK 753
           LSG+RWIEHYGE+ I+N     C CK+ F+K  YW++N +E++G V D+ GKAV+RLFGK
Sbjct: 741 LSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGK 800

Query: 754 WHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPD 813
           WHE +YCG   S+ C+WR   MP  YE YY FT+FA+ELNE+DP  K LLPPTD RFRPD
Sbjct: 801 WHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPD 860

Query: 814 QRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD----DSWVSNGTY 869
           QRFLEEGNLE A  +KQR+E+LQR RRR +EEN++EH P+FF+K  D    ++WVSN TY
Sbjct: 861 QRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTY 920

Query: 870 LELRKDLGFSKLDHPVLW 887
            ELRKD GFSK+D PVLW
Sbjct: 921 WELRKDPGFSKVDSPVLW 938


>gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens]
          Length = 842

 Score =  808 bits (2086), Expect = 0.0
 Identities = 436/886 (49%), Positives = 567/886 (63%), Gaps = 70/886 (7%)

Query: 17  PSRSTSSCSSKQGSRQDSWEVVE------GLRGEMNYTQEPPVQKGFLLKKRKWPLKGWH 70
           P  + SS  S      + WEVVE      G  G M     P  Q+G LLKKRKWPLKGWH
Sbjct: 12  PESAQSSKPSSAQQASELWEVVEEPRVRLGTEGVM-----PERQEGHLLKKRKWPLKGWH 66

Query: 71  KRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKS 130
           KR+F L+ GIL YA ++ DI + KLHG IDV LSVMS+ K ++ IDLDTE++IYHLK+KS
Sbjct: 67  KRYFVLEDGILHYATTRQDITKGKLHGSIDVRLSVMSINKKAQRIDLDTEDNIYHLKIKS 126

Query: 131 EEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSISSRKRSSISKQ 190
           +++F  WV++LR HR+  +                    D   G   S + RK       
Sbjct: 127 QDLFQSWVAQLRAHRLAHR-------------------LDMPRGSLPSTAHRKVPGAQ-- 165

Query: 191 NLFQTGSNVSF--SCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQSMDVLHR 248
               T +  S     G   +V  WL+ S+ +++CS +L+ C   L E+ +LLQS++ LHR
Sbjct: 166 --LPTAATASALPGLGPREKVSSWLRDSDGLDRCSHELSECQGKLQELHRLLQSLESLHR 223

Query: 249 TYSAPAINAIQGG-SFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVRLHSSNPN 307
             SAP I   Q   + E PKK KR+ R W +++  KD               RLH S PN
Sbjct: 224 IPSAPVIPTHQASVTTERPKKGKRTSRMWCTQSFAKD--------DTIGRVGRLHGSVPN 275

Query: 308 LSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREKLKQLMEQ 367
           LS      + + + G   + +++ +Q     +A KV+ +L S    ++ ER++L+ + + 
Sbjct: 276 LSRYLESRDSSGTRGLPPT-DYAHLQRSFWALAQKVHSSLSSVLAALTMERDQLRDMHQG 334

Query: 368 DASSSPSAQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNLAEENSRD 427
              S      +G+  A +             RR+H+ S   D+ A + S  N  E+ +  
Sbjct: 335 SELSR-----MGVSEASTGQ-----------RRLHSLSTSSDTTADSFSSLNPEEQEALY 378

Query: 428 -ENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDD-SYVSDISDNLSLD 485
            + R L  QLS  S LS+ DS +EFFDA EVLLS SSSENE S+++ S  S+I+ +LS +
Sbjct: 379 MKGRELTPQLSQTSILSLADSHTEFFDACEVLLSASSSENEGSEEEESCTSEITTSLSEE 438

Query: 486 NLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAM 545
            L  DL    +        GR     RR CLPA     +++SLWNILRNNIGKDLSKV+M
Sbjct: 439 ML--DLRGAERCQKGGCVPGRPMGPPRRRCLPAASGPGADVSLWNILRNNIGKDLSKVSM 496

Query: 546 PVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPF 605
           PV+LNEPLNTLQRLCEELEYS LLD+A++I  P ERMVY+AAFA+SAY+S+Y+RAG KPF
Sbjct: 497 PVQLNEPLNTLQRLCEELEYSSLLDQASRIADPCERMVYIAAFAVSAYSSTYHRAGCKPF 556

Query: 606 NPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIV 665
           NPVLGETYEC R D+GF+F SEQVSHHPPISACHAES NF FWQD++WKNKFWGKS+EIV
Sbjct: 557 NPVLGETYECERPDRGFRFISEQVSHHPPISACHAESENFAFWQDMKWKNKFWGKSLEIV 616

Query: 666 PIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKA 725
           P+GT +V+LP FGDHFEWNKVTSCIHN+LSGQRWIEHYGE++I+N  D SC+CK+ F KA
Sbjct: 617 PVGTVNVSLPRFGDHFEWNKVTSCIHNVLSGQRWIEHYGEVLIRNTQDSSCHCKITFCKA 676

Query: 726 KYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSF 785
           KYWS+N HE++G V  RSG+ +HRLFGKWHE +Y G      C+W+ N MP  +E+ + F
Sbjct: 677 KYWSSNVHEVQGAVLSRSGRVLHRLFGKWHEGLYRGPTPGGQCIWKPNSMPPDHERNFGF 736

Query: 786 TQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEE 845
           TQFALELNE+    K  LP TDTR RPDQR+LEEGN++ AE QK+RIEQLQR+RR+V+EE
Sbjct: 737 TQFALELNELTAELKRSLPSTDTRLRPDQRYLEEGNIQAAEAQKRRIEQLQRDRRKVMEE 796

Query: 846 NHVEHQPRFFRKSDDDS----WVSNGTYLELRKDLGFSKLDHPVLW 887
           N++ HQ RFFR+  D S    WV+N TY  LR + G+  +D  VLW
Sbjct: 797 NNIVHQARFFRRQTDSSGKEWWVTNNTYWRLRAEPGYGNMDGAVLW 842


>gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo
           sapiens]
          Length = 950

 Score =  296 bits (759), Expect = 4e-80
 Identities = 181/519 (34%), Positives = 268/519 (51%), Gaps = 78/519 (15%)

Query: 419 NLAEENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSY--VS 476
           N   E  +++N+ L   L   +        +E  + ++ L+  S   + +S+D+ Y  +S
Sbjct: 430 NFKLEQEQEKNKILSEALETLA--------TEHHELEQSLVKGSPPASILSEDEFYDALS 481

Query: 477 DISDNLSLDNL----SNDLDNERQTLGPVLDSGREAKS------------RRRTCLPAPC 520
           D     SL  L    +   + E + LG       E K             + RT LP+P 
Sbjct: 482 DSESERSLSRLEAVTARSFEEEGEHLGSRKHRMSEEKDCGGGDALSNGIKKHRTSLPSPM 541

Query: 521 PSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLE 580
            S ++ S+W+ILR  IG +LSK+ MPV  NEPL+ LQRL E +E++ L+ KA+ +  P+E
Sbjct: 542 FSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVE 601

Query: 581 RMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHA 640
           RM  VAAFA+SA AS + R G KPFNP+LGETYE +R+D GF+  SEQVSHHPPISA HA
Sbjct: 602 RMQCVAAFAVSAVASQWERTG-KPFNPLLGETYELVRDDLGFRLISEQVSHHPPISAFHA 660

Query: 641 ESRN--FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQR 698
           E  N  F+F   +  K KFWGKS+E  P GT  + L    + + W   T C+HNI+ G+ 
Sbjct: 661 EGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKL 720

Query: 699 WIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESI 758
           WIE YG + I N H     C +NF     +    H++EG + D+S K +  L+GKW E +
Sbjct: 721 WIEQYGNVEIIN-HKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKWTECL 779

Query: 759 YCGGGSS-------------------------------------------SACVWRANPM 775
           Y    ++                                           S  +WR  P 
Sbjct: 780 YSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIAPR 839

Query: 776 PKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQL 835
           P    Q Y+FT FA+ LNE+D   +S++P TD R RPD R +E G +++A  +K+R+E+ 
Sbjct: 840 PPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEK 899

Query: 836 QRERRRVLEENHVEHQPRFFRKSDD-----DSWVSNGTY 869
           QR  R+   ++  + + R+F +  +       W+ +G+Y
Sbjct: 900 QRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIYSGSY 938



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 28/133 (21%), Positives = 52/133 (39%), Gaps = 17/133 (12%)

Query: 68  GWHKRFFYLDKGILKYAKSQTD-IEREKLHGCIDVGLSVMSVKKSSKCI----DLDTEEH 122
           GW   +  L+ G+L + + Q D +      GC  +  +V +VK +  C+      D   H
Sbjct: 250 GWRLFWVVLEHGVLSWYRKQPDAVHNIYRQGCKHLTQAVCTVKSTDSCLFFIKCFDDTIH 309

Query: 123 IYHLKVKS-EEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSISS 181
            + +   S ++  ++W+  +  H  Y             H+ S   +TD       S + 
Sbjct: 310 GFRVPKNSLQQSREDWLEAIEEHSAYS-----------THYCSQDQLTDEEEEDTVSAAD 358

Query: 182 RKRSSISKQNLFQ 194
            K+S    Q+  Q
Sbjct: 359 LKKSLEKAQSCQQ 371


>gi|21450853 oxysterol-binding protein-like protein 2 isoform 2
           [Homo sapiens]
          Length = 480

 Score =  293 bits (751), Expect = 4e-79
 Identities = 180/475 (37%), Positives = 251/475 (52%), Gaps = 63/475 (13%)

Query: 450 EFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAK 509
           EFFDA     S +SS  E S+ +  V+ + D  +  N       ER    P  ++G +  
Sbjct: 6   EFFDAVTGFDSDNSS-GEFSEANQKVTGMIDLDTSKNNRIGKTGER----PSQENGIQ-- 58

Query: 510 SRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELL 569
            + RT LPAP  S S+ S+W IL+  +G +LSK+ MP+  NEPL+ LQR+ E +E+  L+
Sbjct: 59  -KHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLI 117

Query: 570 DKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQV 629
            +A+  P PLERM  VAAFA+SA AS + R G KPFNP+LGETYE IRED GF+F SEQV
Sbjct: 118 HRASCQPQPLERMQSVAAFAVSAVASQWERTG-KPFNPLLGETYELIREDLGFRFISEQV 176

Query: 630 SHHPPISACHAESRN--FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVT 687
           SHHPPISA H+E  N  F+F   +  K KFWGKS+E  P GT  + L    + + W   T
Sbjct: 177 SHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPT 236

Query: 688 SCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAV 747
            C+HN++ G+ WIE YG + I N H     C ++F     +    H++EG + D++ K +
Sbjct: 237 CCVHNVIIGKLWIEQYGTVEILN-HRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKL 295

Query: 748 HRLFGKWHESIY----------------------------CGGGSS-------------- 765
             ++GKW E ++                             G   S              
Sbjct: 296 FMIYGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQ 355

Query: 766 ----SACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGN 821
               S  +WR N  P    Q Y+FT F + LNE++   +  LPPTD R RPD R +E GN
Sbjct: 356 VIPGSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGN 415

Query: 822 LEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD-----DSWVSNGTYLE 871
           ++ A  +K+R+E+ QRE RR   +   E Q R+F   ++       W+  G Y E
Sbjct: 416 MDLASQEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFE 470


>gi|4505531 oxysterol binding protein [Homo sapiens]
          Length = 807

 Score =  293 bits (750), Expect = 5e-79
 Identities = 171/430 (39%), Positives = 251/430 (58%), Gaps = 45/430 (10%)

Query: 437 SNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQ 496
           S +  +S  D  +EFFDA E++  P +  ++ +   S +S  S ++SLD      +  + 
Sbjct: 345 SGKGDMSDEDDENEFFDAPEIITMPENLGHKRTG--SNISGASSDISLD------EQYKH 396

Query: 497 TLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTL 556
            L        E K  +RT +P     + +++LW+I++N IGK+LSK+ MPV  NEPL+ L
Sbjct: 397 QL-------EETKKEKRTRIPYK--PNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSML 447

Query: 557 QRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECI 616
           QRL E+LEY ELLD+AA+  + LE++ YVAAF +S+Y+++ +R  SKPFNP+LGET+E  
Sbjct: 448 QRLTEDLEYHELLDRAAKCENSLEQLCYVAAFTVSSYSTTVFRT-SKPFNPLLGETFELD 506

Query: 617 R-EDKGFQFFSEQVSHHPPISACHAESRN-FVFWQDVRWKNKFWGKSMEIVPIGTTHVTL 674
           R E+ G++   EQVSHHPP +A HAES+N +   Q+++  +KF GK + I+P+GT H   
Sbjct: 507 RLEENGYRSLCEQVSHHPPAAAHHAESKNGWTLRQEIKITSKFRGKYLSIMPLGTIHCIF 566

Query: 675 PVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTN-AH 733
              G H+ W KVT+ +HNI+ G+ WI+  GEI I N H     C + F+   Y+S + A 
Sbjct: 567 HATGHHYTWKKVTTTVHNIIVGKLWIDQSGEIDIVN-HKTGDKCNLKFVPYSYFSRDVAR 625

Query: 734 EIEGTVFDRSGKAVHRLFGKWHESIYC---------GGG----------SSSACVWRANP 774
           ++ G V D SGK    L G W E + C          GG           S   +W+ NP
Sbjct: 626 KVTGEVTDPSGKVHFALLGTWDEKMECFKVQPVIGENGGDARQRGHEAEESRVMLWKRNP 685

Query: 775 MPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQ 834
           +PK  E  Y F++ AL LN  +  +     PTD+R RPDQR +E G  +EA  +KQR+E+
Sbjct: 686 LPKNAENMYYFSELALTLNAWESGT----APTDSRLRPDQRLMENGRWDEANAEKQRLEE 741

Query: 835 LQRERRRVLE 844
            QR  R+  E
Sbjct: 742 KQRLSRKKRE 751



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 27/88 (30%), Positives = 48/88 (54%), Gaps = 2/88 (2%)

Query: 54  QKGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSK 113
           ++G+L K   + +KG+ +R+F L  G+L Y +S+ ++ R    G I++  + ++V+ S  
Sbjct: 91  REGWLFKWTNY-IKGYQRRWFVLSNGLLSYYRSKAEM-RHTCRGTINLATANITVEDSCN 148

Query: 114 CIDLDTEEHIYHLKVKSEEVFDEWVSKL 141
            I  +     YHLK  SE     WV+ L
Sbjct: 149 FIISNGGAQTYHLKASSEVERQRWVTAL 176


>gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo
           sapiens]
          Length = 437

 Score =  291 bits (746), Expect = 1e-78
 Identities = 160/409 (39%), Positives = 229/409 (55%), Gaps = 52/409 (12%)

Query: 511 RRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLD 570
           + RT LP+P  S ++ S+W+ILR  IG +LSK+ MPV  NEPL+ LQRL E +E++ L+ 
Sbjct: 19  KHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIH 78

Query: 571 KAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVS 630
           KA+ +  P+ERM  VAAFA+SA AS + R G KPFNP+LGETYE +R+D GF+  SEQVS
Sbjct: 79  KASSLSDPVERMQCVAAFAVSAVASQWERTG-KPFNPLLGETYELVRDDLGFRLISEQVS 137

Query: 631 HHPPISACHAESRN--FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTS 688
           HHPPISA HAE  N  F+F   +  K KFWGKS+E  P GT  + L    + + W   T 
Sbjct: 138 HHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTC 197

Query: 689 CIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVH 748
           C+HNI+ G+ WIE YG + I N H     C +NF     +    H++EG + D+S K + 
Sbjct: 198 CVHNIIVGKLWIEQYGNVEIIN-HKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLC 256

Query: 749 RLFGKWHESIYCGGGSS------------------------------------------- 765
            L+GKW E +Y    ++                                           
Sbjct: 257 ALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPG 316

Query: 766 SACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEA 825
           S  +WR  P P    Q Y+FT FA+ LNE+D   +S++P TD R RPD R +E G +++A
Sbjct: 317 SVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQA 376

Query: 826 EIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD-----DSWVSNGTY 869
             +K+R+E+ QR  R+   ++  + + R+F +  +       W+ +G+Y
Sbjct: 377 SEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIYSGSY 425


>gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [Homo
           sapiens]
          Length = 468

 Score =  289 bits (739), Expect = 9e-78
 Identities = 163/414 (39%), Positives = 225/414 (54%), Gaps = 55/414 (13%)

Query: 511 RRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLD 570
           + RT LPAP  S S+ S+W IL+  +G +LSK+ MP+  NEPL+ LQR+ E +E+  L+ 
Sbjct: 47  KHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIH 106

Query: 571 KAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVS 630
           +A+  P PLERM  VAAFA+SA AS + R G KPFNP+LGETYE IRED GF+F SEQVS
Sbjct: 107 RASCQPQPLERMQSVAAFAVSAVASQWERTG-KPFNPLLGETYELIREDLGFRFISEQVS 165

Query: 631 HHPPISACHAESRN--FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTS 688
           HHPPISA H+E  N  F+F   +  K KFWGKS+E  P GT  + L    + + W   T 
Sbjct: 166 HHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTC 225

Query: 689 CIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVH 748
           C+HN++ G+ WIE YG + I N H     C ++F     +    H++EG + D++ K + 
Sbjct: 226 CVHNVIIGKLWIEQYGTVEILN-HRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLF 284

Query: 749 RLFGKWHESIY----------------------------CGGGSS--------------- 765
            ++GKW E ++                             G   S               
Sbjct: 285 MIYGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQV 344

Query: 766 ---SACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNL 822
              S  +WR N  P    Q Y+FT F + LNE++   +  LPPTD R RPD R +E GN+
Sbjct: 345 IPGSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNM 404

Query: 823 EEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD-----DSWVSNGTYLE 871
           + A  +K+R+E+ QRE RR   +   E Q R+F   ++       W+  G Y E
Sbjct: 405 DLASQEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFE 458


>gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens]
          Length = 916

 Score =  266 bits (679), Expect = 8e-71
 Identities = 160/423 (37%), Positives = 241/423 (56%), Gaps = 36/423 (8%)

Query: 446 DSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSG 505
           D  +E+FDA E   S  +   E  +D       +   S+D  S D   +  +L P   S 
Sbjct: 447 DEDTEYFDAMEDSTSFITVITEAKEDSRKAEGSTGTSSVDWSSADNVLDGASLVPKGSS- 505

Query: 506 REAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEY 565
              K +RR  +P     + +++LW+I++N IG++LS++ MPV  NEPL+ LQRL E+LEY
Sbjct: 506 ---KVKRRVRIPNK--PNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEY 560

Query: 566 SELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIR-EDKGFQF 624
             LLDKA    S +E+M  VAAF++S+Y+++ +R  +KPFNP+LGET+E  R +D G + 
Sbjct: 561 HHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRI-AKPFNPMLGETFELDRLDDMGLRS 619

Query: 625 FSEQVSHHPPISACHAESRN-FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEW 683
             EQVSHHPP +A +  S++ +  WQ++   +KF GK + I+P+G  H+     G+H+ W
Sbjct: 620 LCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVW 679

Query: 684 NKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTN-AHEIEGTVFDR 742
            K TS +HNI+ G+ WI+  G+I I N H  +  C++ F+   Y+S   A ++ G V D 
Sbjct: 680 RKSTSTVHNIIVGKLWIDQSGDIEIVN-HKTNDRCQLKFLPYSYFSKEAARKVTGVVSDS 738

Query: 743 SGKAVHRLFGKWHESIYCG--------------------GGSSSACVWRANPMPKGYEQY 782
            GKA + L G W E + C                        S+  +W+  P+P+  E  
Sbjct: 739 QGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENM 798

Query: 783 YSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQR-ERRR 841
           Y F++ AL LNE +      + PTD+R RPDQR +E+G  +EA  +KQR+E+ QR  RRR
Sbjct: 799 YYFSELALTLNEHEEG----VAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRR 854

Query: 842 VLE 844
            LE
Sbjct: 855 RLE 857



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 7/89 (7%)

Query: 55  KGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCI-DVGLSVMSVKKSSK 113
           +G+LLK   + LKG+ +R+F L  G+L Y ++Q     E  H C   + LS   +     
Sbjct: 186 EGWLLKWTNY-LKGYQRRWFVLGNGLLSYYRNQ----GEMAHTCRGTINLSTAHIDTEDS 240

Query: 114 C-IDLDTEEHIYHLKVKSEEVFDEWVSKL 141
           C I L +    YHLK  SE    +W++ L
Sbjct: 241 CGILLTSGARSYHLKASSEVDRQQWITAL 269


>gi|14149740 oxysterol-binding protein-like protein 5 isoform a
           [Homo sapiens]
          Length = 879

 Score =  106 bits (265), Expect = 8e-23
 Identities = 95/350 (27%), Positives = 161/350 (46%), Gaps = 33/350 (9%)

Query: 522 SSSNISL-WNILRN-NIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPL 579
           S  N SL W +L+    G DLS+V +P  + EP + L +L +   +++LL +AA      
Sbjct: 364 SEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAY 423

Query: 580 ERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYECI----REDKGFQFFSEQVSHH 632
            RM  V  +    Y S +Y+      KP+NP+LGET+ C     + D    + +EQVSHH
Sbjct: 424 SRMKLVLRW----YLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHH 479

Query: 633 PPISACHAESR--NFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCI 690
           PP+SA H  +R   F     +  K++F+G S+  +  G   +T     + +      +  
Sbjct: 480 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 539

Query: 691 HNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYW--STNAHEIEGTVFDRSGKAV- 747
             IL G   +E  G++ I+    ++   ++ F    ++  ST+ ++I G +   SG+ V 
Sbjct: 540 KGILYGTMTLELGGKVTIE-CAKNNFQAQLEFKLKPFFGGSTSINQISGKI--TSGEEVL 596

Query: 748 HRLFGKWHESIYC--GGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPP 805
             L G W   ++    G  SSA  W     P G  +     Q  + L E        L  
Sbjct: 597 ASLSGHWDRDVFIKEEGSGSSALFW----TPSGEVRRQRLRQHTVPLEEQTELESERL-- 650

Query: 806 TDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFF 855
               ++   R + +G+   A  +K  +E+ QR+R R  +E+ +  +P+ F
Sbjct: 651 ----WQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLF 696


>gi|221136766 oxysterol-binding protein-like protein 5 isoform b
           [Homo sapiens]
          Length = 811

 Score =  106 bits (265), Expect = 8e-23
 Identities = 95/350 (27%), Positives = 161/350 (46%), Gaps = 33/350 (9%)

Query: 522 SSSNISL-WNILRN-NIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPL 579
           S  N SL W +L+    G DLS+V +P  + EP + L +L +   +++LL +AA      
Sbjct: 296 SEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAY 355

Query: 580 ERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYECI----REDKGFQFFSEQVSHH 632
            RM  V  +    Y S +Y+      KP+NP+LGET+ C     + D    + +EQVSHH
Sbjct: 356 SRMKLVLRW----YLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHH 411

Query: 633 PPISACHAESR--NFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCI 690
           PP+SA H  +R   F     +  K++F+G S+  +  G   +T     + +      +  
Sbjct: 412 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 471

Query: 691 HNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYW--STNAHEIEGTVFDRSGKAV- 747
             IL G   +E  G++ I+    ++   ++ F    ++  ST+ ++I G +   SG+ V 
Sbjct: 472 KGILYGTMTLELGGKVTIE-CAKNNFQAQLEFKLKPFFGGSTSINQISGKI--TSGEEVL 528

Query: 748 HRLFGKWHESIYC--GGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPP 805
             L G W   ++    G  SSA  W     P G  +     Q  + L E        L  
Sbjct: 529 ASLSGHWDRDVFIKEEGSGSSALFW----TPSGEVRRQRLRQHTVPLEEQTELESERL-- 582

Query: 806 TDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFF 855
               ++   R + +G+   A  +K  +E+ QR+R R  +E+ +  +P+ F
Sbjct: 583 ----WQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLF 628


>gi|22035609 oxysterol-binding protein-like protein 5 isoform b
           [Homo sapiens]
          Length = 811

 Score =  106 bits (265), Expect = 8e-23
 Identities = 95/350 (27%), Positives = 161/350 (46%), Gaps = 33/350 (9%)

Query: 522 SSSNISL-WNILRN-NIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPL 579
           S  N SL W +L+    G DLS+V +P  + EP + L +L +   +++LL +AA      
Sbjct: 296 SEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAY 355

Query: 580 ERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYECI----REDKGFQFFSEQVSHH 632
            RM  V  +    Y S +Y+      KP+NP+LGET+ C     + D    + +EQVSHH
Sbjct: 356 SRMKLVLRW----YLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHH 411

Query: 633 PPISACHAESR--NFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCI 690
           PP+SA H  +R   F     +  K++F+G S+  +  G   +T     + +      +  
Sbjct: 412 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 471

Query: 691 HNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYW--STNAHEIEGTVFDRSGKAV- 747
             IL G   +E  G++ I+    ++   ++ F    ++  ST+ ++I G +   SG+ V 
Sbjct: 472 KGILYGTMTLELGGKVTIE-CAKNNFQAQLEFKLKPFFGGSTSINQISGKI--TSGEEVL 528

Query: 748 HRLFGKWHESIYC--GGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPP 805
             L G W   ++    G  SSA  W     P G  +     Q  + L E        L  
Sbjct: 529 ASLSGHWDRDVFIKEEGSGSSALFW----TPSGEVRRQRLRQHTVPLEEQTELESERL-- 582

Query: 806 TDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFF 855
               ++   R + +G+   A  +K  +E+ QR+R R  +E+ +  +P+ F
Sbjct: 583 ----WQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLF 628


>gi|51243032 oxysterol-binding protein-like protein 8 isoform b
           [Homo sapiens]
          Length = 847

 Score = 90.1 bits (222), Expect = 8e-18
 Identities = 74/279 (26%), Positives = 126/279 (45%), Gaps = 24/279 (8%)

Query: 450 EFFDAQEVLLSPSSSENEISDD--DSYVSDISDNLSLDNLSNDLDN--ERQTLGPVLDSG 505
           + F  Q++    S  EN+   D  D+ V   S+    D      D+  E + + P+ ++ 
Sbjct: 277 QHFKDQDMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETT 336

Query: 506 REAKSRRRTCLPAPCPSSSNIS------LWNILRN-NIGKDLSKVAMPVELNEPLNTLQR 558
              +S            +  +S      +W +L+    G DLSKV +P  + EP + L +
Sbjct: 337 YTEQSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDK 396

Query: 559 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAG---SKPFNPVLGETYEC 615
           L +   +++ L +AA   +P  R+  V    +  Y S +Y+      KP+NP+LGET+ C
Sbjct: 397 LSDYYYHADFLSEAALEENPYFRLKKV----VKWYLSGFYKKPKGLKKPYNPILGETFRC 452

Query: 616 I----REDKGFQFFSEQVSHHPPISACHAESR--NFVFWQDVRWKNKFWGKSMEIVPIGT 669
           +    R +    + +EQVSHHPPISA +  +R   F     +  K+KF+G S+  +  G 
Sbjct: 453 LWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGE 512

Query: 670 THVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVI 708
             +T    G+ +      +    IL G   +E  G + I
Sbjct: 513 ARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNI 551


>gi|18079218 oxysterol-binding protein-like protein 8 isoform a
           [Homo sapiens]
          Length = 889

 Score = 90.1 bits (222), Expect = 8e-18
 Identities = 74/279 (26%), Positives = 126/279 (45%), Gaps = 24/279 (8%)

Query: 450 EFFDAQEVLLSPSSSENEISDD--DSYVSDISDNLSLDNLSNDLDN--ERQTLGPVLDSG 505
           + F  Q++    S  EN+   D  D+ V   S+    D      D+  E + + P+ ++ 
Sbjct: 319 QHFKDQDMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETT 378

Query: 506 REAKSRRRTCLPAPCPSSSNIS------LWNILRN-NIGKDLSKVAMPVELNEPLNTLQR 558
              +S            +  +S      +W +L+    G DLSKV +P  + EP + L +
Sbjct: 379 YTEQSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDK 438

Query: 559 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAG---SKPFNPVLGETYEC 615
           L +   +++ L +AA   +P  R+  V    +  Y S +Y+      KP+NP+LGET+ C
Sbjct: 439 LSDYYYHADFLSEAALEENPYFRLKKV----VKWYLSGFYKKPKGLKKPYNPILGETFRC 494

Query: 616 I----REDKGFQFFSEQVSHHPPISACHAESR--NFVFWQDVRWKNKFWGKSMEIVPIGT 669
           +    R +    + +EQVSHHPPISA +  +R   F     +  K+KF+G S+  +  G 
Sbjct: 495 LWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGE 554

Query: 670 THVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVI 708
             +T    G+ +      +    IL G   +E  G + I
Sbjct: 555 ARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNI 593


>gi|20070331 oxysterol binding protein-like 9 isoform e [Homo
           sapiens]
          Length = 736

 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)

Query: 443 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 498
           S + S  EF+DA E   S SS +  I    S      S   ++L   + +  L++     
Sbjct: 287 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 346

Query: 499 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 558
               D       R             ++ +  + +  +G DL+KV +P  + E  + L+ 
Sbjct: 347 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 406

Query: 559 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 615
             +   + +L    +    P +RMV V  + +SA+ +   R GS   KP+NP+LGE ++C
Sbjct: 407 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 464

Query: 616 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 652
                         + E            F +EQVSHHPPISA +AE  ++   F   + 
Sbjct: 465 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 524

Query: 653 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 712
            K+KF G S+ +  IG   V+   + +H+          +IL+   W+E  GE  I N  
Sbjct: 525 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 582

Query: 713 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 770
                  + F    ++    H I   +F     K+   + G+W+  +Y    +    V+ 
Sbjct: 583 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 642

Query: 771 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 828
             +  P+ K   +         + NE +  S+SL    D  F      L+  +++ A   
Sbjct: 643 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 687

Query: 829 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 880
           K R+E+ QR   R  +E  ++ + R F + D + WV +   L   K LG +K
Sbjct: 688 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 735



 Score = 38.9 bits (89), Expect = 0.021
 Identities = 27/118 (22%), Positives = 51/118 (43%), Gaps = 9/118 (7%)

Query: 63  KWP--LKGWHKRFFYLD--KGILKYAKSQTDIEREKLHGCIDVGLSVMSV-KKSSKCIDL 117
           KW   +KGW  R+F LD   G+L Y  S+  + R    GC+ +  +V+ +  +      +
Sbjct: 11  KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70

Query: 118 DTEEHIYHLKVKSEEVFDEWVSKLR----HHRMYRQNEIAMFPHEVNHFFSGSTITDS 171
             ++  +H + +  +  ++W+  L      H +  Q   + F   V  F    T  D+
Sbjct: 71  TVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFDKKLTEADA 128


>gi|22547176 oxysterol binding protein-like 9 isoform f [Homo
           sapiens]
          Length = 746

 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)

Query: 443 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 498
           S + S  EF+DA E   S SS +  I    S      S   ++L   + +  L++     
Sbjct: 297 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 356

Query: 499 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 558
               D       R             ++ +  + +  +G DL+KV +P  + E  + L+ 
Sbjct: 357 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 416

Query: 559 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 615
             +   + +L    +    P +RMV V  + +SA+ +   R GS   KP+NP+LGE ++C
Sbjct: 417 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 474

Query: 616 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 652
                         + E            F +EQVSHHPPISA +AE  ++   F   + 
Sbjct: 475 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 534

Query: 653 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 712
            K+KF G S+ +  IG   V+   + +H+          +IL+   W+E  GE  I N  
Sbjct: 535 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 592

Query: 713 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 770
                  + F    ++    H I   +F     K+   + G+W+  +Y    +    V+ 
Sbjct: 593 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 652

Query: 771 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 828
             +  P+ K   +         + NE +  S+SL    D  F      L+  +++ A   
Sbjct: 653 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 697

Query: 829 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 880
           K R+E+ QR   R  +E  ++ + R F + D + WV +   L   K LG +K
Sbjct: 698 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 745



 Score = 38.5 bits (88), Expect = 0.028
 Identities = 20/84 (23%), Positives = 41/84 (48%), Gaps = 5/84 (5%)

Query: 63  KWP--LKGWHKRFFYLD--KGILKYAKSQTDIEREKLHGCIDVGLSVMSV-KKSSKCIDL 117
           KW   +KGW  R+F LD   G+L Y  S+  + R    GC+ +  +V+ +  +      +
Sbjct: 11  KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70

Query: 118 DTEEHIYHLKVKSEEVFDEWVSKL 141
             ++  +H + +  +  ++W+  L
Sbjct: 71  TVDQKTFHFQARDADEREKWIHAL 94


>gi|22547173 oxysterol binding protein-like 9 isoform d [Homo
           sapiens]
          Length = 723

 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)

Query: 443 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 498
           S + S  EF+DA E   S SS +  I    S      S   ++L   + +  L++     
Sbjct: 274 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 333

Query: 499 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 558
               D       R             ++ +  + +  +G DL+KV +P  + E  + L+ 
Sbjct: 334 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 393

Query: 559 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 615
             +   + +L    +    P +RMV V  + +SA+ +   R GS   KP+NP+LGE ++C
Sbjct: 394 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 451

Query: 616 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 652
                         + E            F +EQVSHHPPISA +AE  ++   F   + 
Sbjct: 452 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 511

Query: 653 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 712
            K+KF G S+ +  IG   V+   + +H+          +IL+   W+E  GE  I N  
Sbjct: 512 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 569

Query: 713 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 770
                  + F    ++    H I   +F     K+   + G+W+  +Y    +    V+ 
Sbjct: 570 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 629

Query: 771 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 828
             +  P+ K   +         + NE +  S+SL    D  F      L+  +++ A   
Sbjct: 630 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 674

Query: 829 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 880
           K R+E+ QR   R  +E  ++ + R F + D + WV +   L   K LG +K
Sbjct: 675 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 722



 Score = 38.9 bits (89), Expect = 0.021
 Identities = 27/118 (22%), Positives = 51/118 (43%), Gaps = 9/118 (7%)

Query: 63  KWP--LKGWHKRFFYLD--KGILKYAKSQTDIEREKLHGCIDVGLSVMSV-KKSSKCIDL 117
           KW   +KGW  R+F LD   G+L Y  S+  + R    GC+ +  +V+ +  +      +
Sbjct: 11  KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70

Query: 118 DTEEHIYHLKVKSEEVFDEWVSKLR----HHRMYRQNEIAMFPHEVNHFFSGSTITDS 171
             ++  +H + +  +  ++W+  L      H +  Q   + F   V  F    T  D+
Sbjct: 71  TVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFDKKLTEADA 128


>gi|22547171 oxysterol binding protein-like 9 isoform c [Homo
           sapiens]
          Length = 626

 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)

Query: 443 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 498
           S + S  EF+DA E   S SS +  I    S      S   ++L   + +  L++     
Sbjct: 177 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 236

Query: 499 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 558
               D       R             ++ +  + +  +G DL+KV +P  + E  + L+ 
Sbjct: 237 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 296

Query: 559 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 615
             +   + +L    +    P +RMV V  + +SA+ +   R GS   KP+NP+LGE ++C
Sbjct: 297 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 354

Query: 616 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 652
                         + E            F +EQVSHHPPISA +AE  ++   F   + 
Sbjct: 355 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 414

Query: 653 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 712
            K+KF G S+ +  IG   V+   + +H+          +IL+   W+E  GE  I N  
Sbjct: 415 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 472

Query: 713 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 770
                  + F    ++    H I   +F     K+   + G+W+  +Y    +    V+ 
Sbjct: 473 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 532

Query: 771 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 828
             +  P+ K   +         + NE +  S+SL    D  F      L+  +++ A   
Sbjct: 533 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 577

Query: 829 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 880
           K R+E+ QR   R  +E  ++ + R F + D + WV +   L   K LG +K
Sbjct: 578 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 625


>gi|22547169 oxysterol binding protein-like 9 isoform b [Homo
           sapiens]
          Length = 571

 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)

Query: 443 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 498
           S + S  EF+DA E   S SS +  I    S      S   ++L   + +  L++     
Sbjct: 122 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 181

Query: 499 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 558
               D       R             ++ +  + +  +G DL+KV +P  + E  + L+ 
Sbjct: 182 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 241

Query: 559 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 615
             +   + +L    +    P +RMV V  + +SA+ +   R GS   KP+NP+LGE ++C
Sbjct: 242 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 299

Query: 616 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 652
                         + E            F +EQVSHHPPISA +AE  ++   F   + 
Sbjct: 300 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 359

Query: 653 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 712
            K+KF G S+ +  IG   V+   + +H+          +IL+   W+E  GE  I N  
Sbjct: 360 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 417

Query: 713 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 770
                  + F    ++    H I   +F     K+   + G+W+  +Y    +    V+ 
Sbjct: 418 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 477

Query: 771 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 828
             +  P+ K   +         + NE +  S+SL    D  F      L+  +++ A   
Sbjct: 478 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 522

Query: 829 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 880
           K R+E+ QR   R  +E  ++ + R F + D + WV +   L   K LG +K
Sbjct: 523 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 570


>gi|22547167 oxysterol binding protein-like 9 isoform a [Homo
           sapiens]
          Length = 558

 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)

Query: 443 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 498
           S + S  EF+DA E   S SS +  I    S      S   ++L   + +  L++     
Sbjct: 109 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 168

Query: 499 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 558
               D       R             ++ +  + +  +G DL+KV +P  + E  + L+ 
Sbjct: 169 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 228

Query: 559 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 615
             +   + +L    +    P +RMV V  + +SA+ +   R GS   KP+NP+LGE ++C
Sbjct: 229 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 286

Query: 616 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 652
                         + E            F +EQVSHHPPISA +AE  ++   F   + 
Sbjct: 287 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 346

Query: 653 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 712
            K+KF G S+ +  IG   V+   + +H+          +IL+   W+E  GE  I N  
Sbjct: 347 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 404

Query: 713 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 770
                  + F    ++    H I   +F     K+   + G+W+  +Y    +    V+ 
Sbjct: 405 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 464

Query: 771 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 828
             +  P+ K   +         + NE +  S+SL    D  F      L+  +++ A   
Sbjct: 465 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 509

Query: 829 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 880
           K R+E+ QR   R  +E  ++ + R F + D + WV +   L   K LG +K
Sbjct: 510 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 557


>gi|22547165 oxysterol binding protein-like 9 isoform a [Homo
           sapiens]
          Length = 558

 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)

Query: 443 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 498
           S + S  EF+DA E   S SS +  I    S      S   ++L   + +  L++     
Sbjct: 109 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 168

Query: 499 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 558
               D       R             ++ +  + +  +G DL+KV +P  + E  + L+ 
Sbjct: 169 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 228

Query: 559 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 615
             +   + +L    +    P +RMV V  + +SA+ +   R GS   KP+NP+LGE ++C
Sbjct: 229 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 286

Query: 616 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 652
                         + E            F +EQVSHHPPISA +AE  ++   F   + 
Sbjct: 287 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 346

Query: 653 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 712
            K+KF G S+ +  IG   V+   + +H+          +IL+   W+E  GE  I N  
Sbjct: 347 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 404

Query: 713 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 770
                  + F    ++    H I   +F     K+   + G+W+  +Y    +    V+ 
Sbjct: 405 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 464

Query: 771 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 828
             +  P+ K   +         + NE +  S+SL    D  F      L+  +++ A   
Sbjct: 465 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 509

Query: 829 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 880
           K R+E+ QR   R  +E  ++ + R F + D + WV +   L   K LG +K
Sbjct: 510 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 557


>gi|19923812 oxysterol-binding protein-like protein 10 [Homo
           sapiens]
          Length = 764

 Score = 89.4 bits (220), Expect = 1e-17
 Identities = 99/440 (22%), Positives = 177/440 (40%), Gaps = 71/440 (16%)

Query: 461 PSSSENEISDDDSYVSDISDNLSL--DNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPA 518
           P+S+E+E +       +    L L  D  S++ D E   LG + D               
Sbjct: 351 PNSAEDEQTSQPEPEPNSGSELVLSEDEKSDNEDKEETELGVMEDQ-------------- 396

Query: 519 PCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSP 578
                 +I L  I +  +G DL+KV +P  + E  + L+   + + + +LL       +P
Sbjct: 397 -----RSIILHLISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAITAGATP 451

Query: 579 LERMVYVAAFAISAYASSYYRA-GSKPFNPVLGETYECIRE------------------- 618
            ER++    + ++A+      A   KP+NP++GET+ C  E                   
Sbjct: 452 EERVICFVEYYLTAFHEGRKGALAKKPYNPIIGETFHCSWEVPKDRVKPKRTASRSPASC 511

Query: 619 ---------DKGFQ--FFSEQVSHHPPISA--CHAESRNFVFWQDVRWKNKFWGKSMEIV 665
                     K ++  F +EQVSHHPPIS   C  E +       V  K+KF G S+ + 
Sbjct: 512 HEHPMADDPSKSYKLRFVAEQVSHHPPISCFYCECEEKRLCVNTHVWTKSKFMGMSVGVS 571

Query: 666 PIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKA 725
            IG   + L   G+ + +   ++   +IL+   W+E  G++ I N         V F   
Sbjct: 572 MIGEGVLRLLEHGEEYVFTLPSAYARSILT-IPWVELGGKVSI-NCAKTGYSATVIFHTK 629

Query: 726 KYWSTNAHEIEGTV-FDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYS 784
            ++    H +   V  + +   V +  G+W+ ++     +    V     +P        
Sbjct: 630 PFYGGKVHRVTAEVKHNPTNTIVCKAHGEWNGTLEFTYNNGETKVIDTTTLP-------- 681

Query: 785 FTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLE 844
                +   ++ P  K     +   +R   R+L  G+++ A  QK+ +E+ QR   R  E
Sbjct: 682 -----VYPKKIRPLEKQGPMESRNLWREVTRYLRLGDIDAATEQKRHLEEKQRVEERKRE 736

Query: 845 ENHVEHQPRFFRKSDDDSWV 864
                 +P++F + + D WV
Sbjct: 737 NLRTPWKPKYFIQ-EGDGWV 755



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 35/156 (22%), Positives = 64/156 (41%), Gaps = 19/156 (12%)

Query: 18  SRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLKKRKWPLKGWHKRFFYLD 77
           SRS ++     GSR     V     G     +EP ++   +L K    L+GW  R+F LD
Sbjct: 42  SRSAAAGLGGGGSRSSPGSVAASPSGGGGRRREPALEG--VLSKYTNLLQGWQNRYFVLD 99

Query: 78  --KGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSS--KCIDLDTEEHIYHLKVKSEEV 133
              GIL+Y  ++   + +K  G + +  +++S+   +    +       ++ L+    + 
Sbjct: 100 FEAGILQYFVNEQS-KHQKPRGVLSLSGAIVSLSDEAPHMLVVYSANGEMFKLRAADAKE 158

Query: 134 FDEWVSKLRHHRMY------------RQNEIAMFPH 157
              WV++LR    Y            R   + + PH
Sbjct: 159 KQFWVTQLRACAKYHMEMNSKSAPSSRSRSLTLLPH 194


>gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]
          Length = 747

 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 76/371 (20%), Positives = 148/371 (39%), Gaps = 60/371 (16%)

Query: 536 IGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYAS 595
           +G DL++V +P  + E  + L+   + + + +L        +  +RM+    + ++++  
Sbjct: 379 LGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHE 438

Query: 596 SYYRA-GSKPFNPVLGETYECI------------------------------------RE 618
               A   KP+NP++GET+ C                                      +
Sbjct: 439 GRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSD 498

Query: 619 DKGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPV 676
               +F +EQVSHHPP+S  +AE   R       V  K+KF G S+ +  +G   ++L  
Sbjct: 499 CYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLE 558

Query: 677 FGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIE 736
            G+ + ++   +   +IL+   W+E  G++ + N         + F    ++    H + 
Sbjct: 559 HGEEYTFSLPCAYARSILT-VPWVELGGKVSV-NCAKTGYSASITFHTKPFYGGKLHRVT 616

Query: 737 GTV-FDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEM 795
             V  + +   V R+ G+W+  +                   G  +Y   T+ A+    +
Sbjct: 617 AEVKHNITNTVVCRVQGEWNSVL-------------EFTYSNGETKYVDLTKLAVTKKRV 663

Query: 796 DPSSKSLLPPTDTR--FRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPR 853
            P  K    P ++R  ++     L E  +++A   K  +E+ QR   R   E     + +
Sbjct: 664 RPLEKQ--DPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTK 721

Query: 854 FFRKSDDDSWV 864
           +F K + D WV
Sbjct: 722 YFIK-EGDGWV 731


>gi|217416392 pleckstrin homology domain containing, family H (with
           MyTH4 domain) member 2 [Homo sapiens]
          Length = 1493

 Score = 57.4 bits (137), Expect = 6e-08
 Identities = 37/113 (32%), Positives = 61/113 (53%), Gaps = 4/113 (3%)

Query: 46  NYTQEPPVQKGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSV 105
           N   EP  + G+LLK     +K W +R+F L  G L Y KS +D+ R K  G I++  S 
Sbjct: 698 NGKNEPLEKSGYLLKM-SGKVKSWKRRWFVLKGGELLYYKSPSDVIR-KPQGHIELSASC 755

Query: 106 MSVKKSSK-CIDLDTEEHIYHLKVKSEEVFDEWVSKLRH-HRMYRQNEIAMFP 156
             ++  +K  + L TE+H Y+L   S  + +EW+  L++  R+   N +++ P
Sbjct: 756 SILRGDNKQTVQLTTEKHTYYLTADSPNILEEWIKVLQNVLRVQAANPLSLQP 808


>gi|55741447 pleckstrin homology domain containing, family H (with
           MyTH4 domain) member 1 [Homo sapiens]
          Length = 1364

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 28/90 (31%), Positives = 49/90 (54%), Gaps = 3/90 (3%)

Query: 54  QKGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVK-KSS 112
           + G+LLK     +K W +R+F L +G + Y KS +D+ R K  G +D+      V+ + S
Sbjct: 581 KSGYLLKMGS-QVKTWKRRWFVLRQGQIMYYKSPSDVIR-KPQGQVDLNSRCQIVRGEGS 638

Query: 113 KCIDLDTEEHIYHLKVKSEEVFDEWVSKLR 142
           +   L +E+  Y+L   S  + +EW+  L+
Sbjct: 639 QTFQLISEKKTYYLTADSPSLLEEWIRVLQ 668


>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
            sapiens]
          Length = 1843

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 53/221 (23%), Positives = 102/221 (46%), Gaps = 25/221 (11%)

Query: 283  KDAKGTLQVPKPFSGPVRLHSSNPNLSTLDFGEEKNYS-DGSETSSEFSKMQEDLCHIAH 341
            K  K   +  K      R+  S+P +S    GE+  +  +  ET+ E  K+++ L  +  
Sbjct: 998  KTVKKNYEALKQRQDEERMVQSSPPIS----GEDNKWERESQETTRELLKVKDRLIEVER 1053

Query: 342  KVYFTLRSAFNIMSAEREKLKQLMEQDASSSPSAQVIGLKNALSSALAQNTDLKERLRRI 401
                TL++      A + +LKQL  Q+  ++  AQ++ L+    S   QNT L+ +  ++
Sbjct: 1054 N-NATLQAE---KQALKTQLKQLETQN--NNLQAQILALQRQTVSLQEQNTTLQTQNAKL 1107

Query: 402  HAESLLLDSPAVAKSGDN----LAEENSRDENRALVHQLSNESRLSITDSLSEFFDAQEV 457
              E+  L+S + +    N    + + +  +EN +++ +   E   S+ DSL +  +  E+
Sbjct: 1108 QVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKE--REDLKSLYDSLIKDHEKLEL 1165

Query: 458  LLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTL 498
            L    +SE        Y S IS + +L +   +L+ E + L
Sbjct: 1166 LHERQASE--------YESLISKHGTLKSAHKNLEVEHRDL 1198


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.130    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,618,896
Number of Sequences: 37866
Number of extensions: 1590269
Number of successful extensions: 6174
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 121
Number of HSP's that attempted gapping in prelim test: 5855
Number of HSP's gapped (non-prelim): 377
length of query: 887
length of database: 18,247,518
effective HSP length: 111
effective length of query: 776
effective length of database: 14,044,392
effective search space: 10898448192
effective search space used: 10898448192
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.