Guide to the Human Genome
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Search of human proteins with 8923143

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|8923143 ganglioside induced differentiation associated
protein 2 isoform a [Homo sapiens]
         (497 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|8923143 ganglioside induced differentiation associated protei...  1003   0.0  
gi|207450721 ganglioside induced differentiation associated prot...   970   0.0  
gi|13569840 MACRO domain containing 1 [Homo sapiens]                  122   1e-27
gi|117968621 MACRO domain containing 2 isoform 1 [Homo sapiens]       120   2e-27
gi|4757766 Rho GTPase activating protein 1 [Homo sapiens]              76   8e-14
gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens]                71   2e-12
gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo sapi...    71   2e-12
gi|29336043 caytaxin [Homo sapiens]                                    61   3e-09
gi|162287219 prune homolog 2 [Homo sapiens]                            57   5e-08
gi|168480080 BCL2/adenovirus E1B 19kD interacting protein 2 [Hom...    56   9e-08
gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo sapi...    56   9e-08
gi|20336746 H2A histone family, member Y isoform 1 [Homo sapiens]      55   1e-07
gi|4758496 H2A histone family, member Y isoform 2 [Homo sapiens]       54   3e-07
gi|93141020 H2A histone family, member Y isoform 2 [Homo sapiens]      54   3e-07
gi|93141018 H2A histone family, member Y isoform 3 [Homo sapiens]      54   3e-07
gi|228008343 BCL2/adenovirus E1B 19kD interacting protein like i...    52   1e-06
gi|109715844 BCL2/adenovirus E1B 19kD interacting protein like i...    52   1e-06
gi|154813199 poly (ADP-ribose) polymerase family, member 14 [Hom...    52   1e-06
gi|8923920 H2A histone family, member Y2 [Homo sapiens]                48   2e-05
gi|226371718 poly (ADP-ribose) polymerase family, member 9 isofo...    48   2e-05
gi|226371716 poly (ADP-ribose) polymerase family, member 9 isofo...    48   2e-05
gi|226371714 poly (ADP-ribose) polymerase family, member 9 isofo...    48   2e-05
gi|226371712 poly (ADP-ribose) polymerase family, member 9 isofo...    48   2e-05
gi|226371710 poly (ADP-ribose) polymerase family, member 9 isofo...    48   2e-05
gi|226371706 poly (ADP-ribose) polymerase family, member 9 isofo...    48   2e-05
gi|109826564 neurofibromin isoform 1 [Homo sapiens]                    39   0.008
gi|4557793 neurofibromin isoform 2 [Homo sapiens]                      39   0.008
gi|165377137 poly (ADP-ribose) polymerase family, member 15 isof...    39   0.014
gi|4506541 retinaldehyde binding protein 1 [Homo sapiens]              33   0.60 
gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]             32   1.3  

>gi|8923143 ganglioside induced differentiation associated protein 2
           isoform a [Homo sapiens]
          Length = 497

 Score = 1003 bits (2592), Expect = 0.0
 Identities = 497/497 (100%), Positives = 497/497 (100%)

Query: 1   MDPLGAPSQFVDVDTLPSWGDSCQDELNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVLWK 60
           MDPLGAPSQFVDVDTLPSWGDSCQDELNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVLWK
Sbjct: 1   MDPLGAPSQFVDVDTLPSWGDSCQDELNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVLWK 60

Query: 61  GDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNL 120
           GDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNL
Sbjct: 61  GDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNL 120

Query: 121 AARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLED 180
           AARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLED
Sbjct: 121 AARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLED 180

Query: 181 ATHIALRTVRRFLEIHGETIEKVVFAVSDLEEGTYQKLLPLYFPRSLKEENRSLPYLPAD 240
           ATHIALRTVRRFLEIHGETIEKVVFAVSDLEEGTYQKLLPLYFPRSLKEENRSLPYLPAD
Sbjct: 181 ATHIALRTVRRFLEIHGETIEKVVFAVSDLEEGTYQKLLPLYFPRSLKEENRSLPYLPAD 240

Query: 241 IGNAEGEPVVPERQIRISEKPGAPEDNQEEEDEGLGVDLSFIGSHAFARMEGDIDKQRKL 300
           IGNAEGEPVVPERQIRISEKPGAPEDNQEEEDEGLGVDLSFIGSHAFARMEGDIDKQRKL
Sbjct: 241 IGNAEGEPVVPERQIRISEKPGAPEDNQEEEDEGLGVDLSFIGSHAFARMEGDIDKQRKL 300

Query: 301 ILQGQLSEAALQKQHQRNYNRWLCQARSEDLSDIASLKALYQTGVDNCGRTVMVVVGRNI 360
           ILQGQLSEAALQKQHQRNYNRWLCQARSEDLSDIASLKALYQTGVDNCGRTVMVVVGRNI
Sbjct: 301 ILQGQLSEAALQKQHQRNYNRWLCQARSEDLSDIASLKALYQTGVDNCGRTVMVVVGRNI 360

Query: 361 PVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRN 420
           PVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRN
Sbjct: 361 PVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRN 420

Query: 421 LKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPFVLEYD 480
           LKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPFVLEYD
Sbjct: 421 LKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPFVLEYD 480

Query: 481 ARENGPYYTSYPPSPDL 497
           ARENGPYYTSYPPSPDL
Sbjct: 481 ARENGPYYTSYPPSPDL 497


>gi|207450721 ganglioside induced differentiation associated protein
           2 isoform b [Homo sapiens]
          Length = 496

 Score =  970 bits (2507), Expect = 0.0
 Identities = 486/497 (97%), Positives = 487/497 (97%), Gaps = 3/497 (0%)

Query: 1   MDPLGAPSQFVDVDTLPSWGDSCQDELNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVLWK 60
           MDPLGAPSQFVDVDTLPSWGDSCQDELNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVLWK
Sbjct: 1   MDPLGAPSQFVDVDTLPSWGDSCQDELNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVLWK 60

Query: 61  GDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNL 120
           GDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNL
Sbjct: 61  GDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNL 120

Query: 121 AARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLED 180
           AARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLED
Sbjct: 121 AARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLED 180

Query: 181 ATHIALRTVRRFLEIHGETIEKVVFAVSDLEEGTYQKLLPLYFPRSLKEENRSLPYLPAD 240
           ATHIALRTVRRFLEIHGETIEKVVFAVSDLEEGTYQKLLPLYFPRSLKEENRSLPYLPAD
Sbjct: 181 ATHIALRTVRRFLEIHGETIEKVVFAVSDLEEGTYQKLLPLYFPRSLKEENRSLPYLPAD 240

Query: 241 IGNAEGEPVVPERQIRISEKPGAPEDNQEEEDEGLGVDLSFIGSHAFARMEGDIDKQRKL 300
           IGNAEGEPVVPERQIRISEKPGAPEDNQEEEDEGLGVDLSFIGSHAFARMEGDIDKQRKL
Sbjct: 241 IGNAEGEPVVPERQIRISEKPGAPEDNQEEEDEGLGVDLSFIGSHAFARMEGDIDKQRKL 300

Query: 301 ILQGQLSEAALQKQHQRNYNRWLCQARSEDLSDIASLKALYQTGVDNCGRTVMVVVGRNI 360
           ILQGQLSEAALQKQHQRNYNRWLCQARSEDLSDIASLKALYQTGVDNCGRTVMVVVGRNI
Sbjct: 301 ILQGQLSEAALQKQHQRNYNRWLCQARSEDLSDIASLKALYQTGVDNCGRTVMVVVGRNI 360

Query: 361 PVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRN 420
           PVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRN
Sbjct: 361 PVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRN 420

Query: 421 LKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPFVLEYD 480
           LKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPFVLEYD
Sbjct: 421 LKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPFVLEYD 480

Query: 481 ARENGPYYTSYPPSPDL 497
           AR      T   PSP +
Sbjct: 481 ARVRS---TRSSPSPGM 494


>gi|13569840 MACRO domain containing 1 [Homo sapiens]
          Length = 325

 Score =  122 bits (305), Expect = 1e-27
 Identities = 66/177 (37%), Positives = 100/177 (56%), Gaps = 1/177 (0%)

Query: 49  NKDVNGKVVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCR 108
           +K +N K+ L + D+  L   AIVN +N SL     V   I   AGP L ++ + L+ C+
Sbjct: 147 DKQLNEKISLLRSDITKLEVDAIVNAANSSLLGGGGVDGCIHRAAGPLLTDECRTLQSCK 206

Query: 109 TGEAKLTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCV 168
           TG+AK+T G+ L A+++IHTVGP        +  + L SCY + L L  E  + SV F  
Sbjct: 207 TGKAKITGGYRLPAKYVIHTVGPIAYGEPSASQAAELRSCYLSSLDLLLEHRLRSVAFPC 266

Query: 169 INSAKRGYPLEDATHIALRTVRRFLEIHGETIEKVVFAV-SDLEEGTYQKLLPLYFP 224
           I++   GYP E A  I L T+R +LE H + +++++  V  + +E  Y+  LP YFP
Sbjct: 267 ISTGVFGYPCEAAAEIVLATLREWLEQHKDKVDRLIICVFLEKDEDIYRSRLPHYFP 323


>gi|117968621 MACRO domain containing 2 isoform 1 [Homo sapiens]
          Length = 425

 Score =  120 bits (302), Expect = 2e-27
 Identities = 79/264 (29%), Positives = 131/264 (49%), Gaps = 27/264 (10%)

Query: 10  FVDVDTLPSWGDSCQDE-LNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVLWKGDVALLNC 68
           ++ ++++ SW +  + +  N  + T E  Q           K +  KV L++GD+ LL  
Sbjct: 34  YIPLNSILSWKEEMKGKGQNDEENTQETSQ---------VKKSLTEKVSLYRGDITLLEV 84

Query: 69  TAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNLAARFIIHT 128
            AIVN +N SL     V   I   AGP L  + + L GC TG AK+T G++L A+++IHT
Sbjct: 85  DAIVNAANASLLGGGGVDGCIHRAAGPCLLAECRNLNGCDTGHAKITCGYDLPAKYVIHT 144

Query: 129 VGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRT 188
           VGP  +     + +  L +CY++ L+L KE ++ SV F  I++   G+P E A  IAL T
Sbjct: 145 VGPIARGHINGSHKEDLANCYKSSLKLVKENNIRSVAFPCISTGIYGFPNEPAAVIALNT 204

Query: 189 VRRFLEIHGETIEKVVFAVSDLEEGTYQKLLPLYFPRSLKEENRSLPYLPADIGNAEGEP 248
           ++ +L  +   +++++F V           L + F    K+ N    +   D  N E E 
Sbjct: 205 IKEWLAKNHHEVDRIIFCV----------FLEVDFKIYKKKMNE---FFSVDDNNEEEED 251

Query: 249 VVPERQIRISEKPGAPEDNQEEED 272
           V    +++       PE+ Q  E+
Sbjct: 252 V----EMKEDSDENGPEEKQSVEE 271


>gi|4757766 Rho GTPase activating protein 1 [Homo sapiens]
          Length = 439

 Score = 75.9 bits (185), Expect = 8e-14
 Identities = 48/149 (32%), Positives = 70/149 (46%), Gaps = 1/149 (0%)

Query: 333 DIASLKALYQTGVDNCGRTVMVVVGRNIPVT-LIDMDKALLYFIHVMDHIAVKEYVLVYF 391
           DIA  + +   G D  GR ++V     +P +  +D  K L Y  H +D     +Y L+Y 
Sbjct: 66  DIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYL 125

Query: 392 HTLTSEYNHLDSDFLKKLYDVVDVKYKRNLKAVYFVHPTFRSKVSTWFFTTFSVSGLKDK 451
           H   +  N     +L+  Y   D KYK+N+KA+Y VHPT   K     F          K
Sbjct: 126 HHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGQK 185

Query: 452 IHHVDSLHQLFSAISPEQIDFPPFVLEYD 480
           I +V+ L +L   +  EQ+  P  VL+YD
Sbjct: 186 IFYVNYLSELSEHVKLEQLGIPRQVLKYD 214


>gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens]
          Length = 555

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 49/167 (29%), Positives = 73/167 (43%), Gaps = 1/167 (0%)

Query: 328 SEDLSDIASLKALYQTGVDNCGRTVMVVVGRNIPVTL-IDMDKALLYFIHVMDHIAVKEY 386
           S    D+A    L   G D  GR V+      +P +  +D  + L Y  + +D     +Y
Sbjct: 133 SHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYLKYTLDQYVENDY 192

Query: 387 VLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRNLKAVYFVHPTFRSKVSTWFFTTFSVS 446
            +VYFH   +  N     +L+  Y   D KYK+NLKA+Y VHPT   KV           
Sbjct: 193 TIVYFHYGLNSRNKPSLGWLQSAYKEFDRKYKKNLKALYVVHPTSFIKVLWNILKPLISH 252

Query: 447 GLKDKIHHVDSLHQLFSAISPEQIDFPPFVLEYDARENGPYYTSYPP 493
               K+ + + L +L   +  +Q+  PP VL YD +    +    PP
Sbjct: 253 KFGKKVIYFNYLSELHEHLKYDQLVIPPEVLRYDEKLQSLHEGRTPP 299


>gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo
           sapiens]
          Length = 433

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 49/167 (29%), Positives = 73/167 (43%), Gaps = 1/167 (0%)

Query: 328 SEDLSDIASLKALYQTGVDNCGRTVMVVVGRNIPVTL-IDMDKALLYFIHVMDHIAVKEY 386
           S    D+A    L   G D  GR V+      +P +  +D  + L Y  + +D     +Y
Sbjct: 11  SHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYLKYTLDQYVENDY 70

Query: 387 VLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRNLKAVYFVHPTFRSKVSTWFFTTFSVS 446
            +VYFH   +  N     +L+  Y   D KYK+NLKA+Y VHPT   KV           
Sbjct: 71  TIVYFHYGLNSRNKPSLGWLQSAYKEFDRKYKKNLKALYVVHPTSFIKVLWNILKPLISH 130

Query: 447 GLKDKIHHVDSLHQLFSAISPEQIDFPPFVLEYDARENGPYYTSYPP 493
               K+ + + L +L   +  +Q+  PP VL YD +    +    PP
Sbjct: 131 KFGKKVIYFNYLSELHEHLKYDQLVIPPEVLRYDEKLQSLHEGRTPP 177


>gi|29336043 caytaxin [Homo sapiens]
          Length = 371

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 35/130 (26%), Positives = 61/130 (46%)

Query: 367 MDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRNLKAVYF 426
           M+   LY I  ++ +  ++Y++VY +  T         +LKK Y ++D + ++NLK++  
Sbjct: 211 MENLFLYVISSLELLVAEDYMIVYLNGATPRRRMPGIGWLKKCYQMIDRRLRKNLKSLII 270

Query: 427 VHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPFVLEYDARENGP 486
           VHP++  +        F      +KI +V SL  L   I  E +  P  VL+Y+      
Sbjct: 271 VHPSWFIRTVLAISRPFISVKFINKIQYVHSLEDLEQLIPMEHVQIPDCVLQYEEERLKA 330

Query: 487 YYTSYPPSPD 496
              S  P P+
Sbjct: 331 RRESARPQPE 340


>gi|162287219 prune homolog 2 [Homo sapiens]
          Length = 3088

 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 30/114 (26%), Positives = 57/114 (50%)

Query: 367  MDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRNLKAVYF 426
            M+   LY I  ++ +  ++Y++VY +  T         ++KK Y ++D + ++NLK+   
Sbjct: 2939 MENLFLYVISTLELMVAEDYMIVYLNGATPRRRMPGLGWMKKCYQMIDRRLRKNLKSFII 2998

Query: 427  VHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPFVLEYD 480
            VHP++  +        F  S    KI +V+SL +L   I  + I  P  +++ D
Sbjct: 2999 VHPSWFIRTILAVTRPFISSKFSSKIKYVNSLSELSGLIPMDCIHIPESIIKLD 3052


>gi|168480080 BCL2/adenovirus E1B 19kD interacting protein 2 [Homo
           sapiens]
          Length = 435

 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 30/119 (25%), Positives = 56/119 (47%)

Query: 367 MDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRNLKAVYF 426
           MD    Y I  ++ +  + Y++VY +  T+        +L+K Y  +D + ++NLK++  
Sbjct: 308 MDNLFKYVIGTLELLVAENYMIVYLNGATTRRKMPSLGWLRKCYQQIDRRLRKNLKSLII 367

Query: 427 VHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPFVLEYDARENG 485
           VHP++  +        F  S    KI +V +L +L   +  E +  P  + + D   NG
Sbjct: 368 VHPSWFIRTLLAVTRPFISSKFSQKIRYVFNLAELAELVPMEYVGIPECIKQVDQELNG 426


>gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo
           sapiens]
          Length = 464

 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 51/198 (25%), Positives = 77/198 (38%), Gaps = 32/198 (16%)

Query: 328 SEDLSDIASLKALYQTGVDNCGRTVMVVVGRNIPVTL-IDMDKALLYFIHVMDHIAVKEY 386
           S    D+A    L   G D  GR V+      +P +  +D  + L Y  + +D     +Y
Sbjct: 11  SHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYLKYTLDQYVENDY 70

Query: 387 VLVYFH---------------TLTSEYNHLDSDF-----------LKK-----LYDVVDV 415
            +VYFH               +   E++  D D            LK+     L    D 
Sbjct: 71  TIVYFHYGLNSRNKPSLGWLQSAYKEFDRKDGDLTMWPRLVSNSKLKRSSHLSLPKYWDY 130

Query: 416 KYKRNLKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPF 475
           +YK+NLKA+Y VHPT   KV               K+ + + L +L   +  +Q+  PP 
Sbjct: 131 RYKKNLKALYVVHPTSFIKVLWNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIPPE 190

Query: 476 VLEYDARENGPYYTSYPP 493
           VL YD +    +    PP
Sbjct: 191 VLRYDEKLQSLHEGRTPP 208


>gi|20336746 H2A histone family, member Y isoform 1 [Homo sapiens]
          Length = 369

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 46/185 (24%), Positives = 84/185 (45%), Gaps = 13/185 (7%)

Query: 32  TTAEIFQEDTVRSPFLYNKDVNGKVVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFM 91
           T A+ F   + +S FL       K+ + + D+A ++  A+V+ +N        V  ++  
Sbjct: 178 TPADGFTVLSTKSLFL-----GQKLQVVQADIASIDSDAVVHPTNTDFYIGGEVGNTLEK 232

Query: 92  LAGPDLKE---DLQKLKG-CRTGEAKLTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYS 147
             G +  E   +L+K  G      A ++ G  L A+F+IH   P + +      E  L  
Sbjct: 233 KGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGA---DKCEELLEK 289

Query: 148 CYRNVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRR-FLEIHGETIEKVVFA 206
             +N L LA ++ + S+ F  I S + G+P + A  + L+ +   F+     +I+ V F 
Sbjct: 290 TVKNCLALADDKKLKSIAFPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFV 349

Query: 207 VSDLE 211
           + D E
Sbjct: 350 LFDSE 354


>gi|4758496 H2A histone family, member Y isoform 2 [Homo sapiens]
          Length = 371

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 38/147 (25%), Positives = 69/147 (46%), Gaps = 8/147 (5%)

Query: 70  AIVNTSNESLTDKNPVSESIFMLAGPDLKE---DLQKLKG-CRTGEAKLTKGFNLAARFI 125
           AI+N +N  +  K+ +  ++    G +  E   +L+K  G      A ++ G  L A+F+
Sbjct: 213 AIINPTNADIDLKDDLGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFV 272

Query: 126 IHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIA 185
           IH   P + +      E  L    +N L LA ++ + S+ F  I S + G+P + A  + 
Sbjct: 273 IHCNSPVWGA---DKCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPKQTAAQLI 329

Query: 186 LRTVRR-FLEIHGETIEKVVFAVSDLE 211
           L+ +   F+     +I+ V F + D E
Sbjct: 330 LKAISSYFVSTMSSSIKTVYFVLFDSE 356


>gi|93141020 H2A histone family, member Y isoform 2 [Homo sapiens]
          Length = 371

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 38/147 (25%), Positives = 69/147 (46%), Gaps = 8/147 (5%)

Query: 70  AIVNTSNESLTDKNPVSESIFMLAGPDLKE---DLQKLKG-CRTGEAKLTKGFNLAARFI 125
           AI+N +N  +  K+ +  ++    G +  E   +L+K  G      A ++ G  L A+F+
Sbjct: 213 AIINPTNADIDLKDDLGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFV 272

Query: 126 IHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIA 185
           IH   P + +      E  L    +N L LA ++ + S+ F  I S + G+P + A  + 
Sbjct: 273 IHCNSPVWGA---DKCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPKQTAAQLI 329

Query: 186 LRTVRR-FLEIHGETIEKVVFAVSDLE 211
           L+ +   F+     +I+ V F + D E
Sbjct: 330 LKAISSYFVSTMSSSIKTVYFVLFDSE 356


>gi|93141018 H2A histone family, member Y isoform 3 [Homo sapiens]
          Length = 372

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 38/147 (25%), Positives = 69/147 (46%), Gaps = 8/147 (5%)

Query: 70  AIVNTSNESLTDKNPVSESIFMLAGPDLKE---DLQKLKG-CRTGEAKLTKGFNLAARFI 125
           AI+N +N  +  K+ +  ++    G +  E   +L+K  G      A ++ G  L A+F+
Sbjct: 214 AIINPTNADIDLKDDLGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFV 273

Query: 126 IHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIA 185
           IH   P + +      E  L    +N L LA ++ + S+ F  I S + G+P + A  + 
Sbjct: 274 IHCNSPVWGA---DKCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPKQTAAQLI 330

Query: 186 LRTVRR-FLEIHGETIEKVVFAVSDLE 211
           L+ +   F+     +I+ V F + D E
Sbjct: 331 LKAISSYFVSTMSSSIKTVYFVLFDSE 357


>gi|228008343 BCL2/adenovirus E1B 19kD interacting protein like
           isoform b [Homo sapiens]
          Length = 275

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 33/127 (25%), Positives = 59/127 (46%)

Query: 359 NIPVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYK 418
           +IP     M+    Y +  ++ +  + Y+LV+    TS        ++++ Y  +D + +
Sbjct: 145 SIPNYTYVMEHLFRYMVGTLELLVAENYLLVHLSGGTSRAQVPPLSWIRQCYRTLDRRLR 204

Query: 419 RNLKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPFVLE 478
           +NL+A+  VH T+  K        F  S    KI  +DSL +L   IS +Q+  P  V +
Sbjct: 205 KNLRALVVVHATWYVKAFLALLRPFISSKFTRKIRFLDSLGELAQLISLDQVHIPEAVRQ 264

Query: 479 YDARENG 485
            D   +G
Sbjct: 265 LDRDLHG 271


>gi|109715844 BCL2/adenovirus E1B 19kD interacting protein like
           isoform a [Homo sapiens]
          Length = 357

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 33/127 (25%), Positives = 59/127 (46%)

Query: 359 NIPVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYK 418
           +IP     M+    Y +  ++ +  + Y+LV+    TS        ++++ Y  +D + +
Sbjct: 227 SIPNYTYVMEHLFRYMVGTLELLVAENYLLVHLSGGTSRAQVPPLSWIRQCYRTLDRRLR 286

Query: 419 RNLKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPFVLE 478
           +NL+A+  VH T+  K        F  S    KI  +DSL +L   IS +Q+  P  V +
Sbjct: 287 KNLRALVVVHATWYVKAFLALLRPFISSKFTRKIRFLDSLGELAQLISLDQVHIPEAVRQ 346

Query: 479 YDARENG 485
            D   +G
Sbjct: 347 LDRDLHG 353


>gi|154813199 poly (ADP-ribose) polymerase family, member 14 [Homo
           sapiens]
          Length = 1801

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 36/127 (28%), Positives = 61/127 (48%), Gaps = 4/127 (3%)

Query: 56  VVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKED---LQKLKG-CRTGE 111
           +++ +GD+A L    +VN SNE L     ++ ++   AGP+L+ D   + K +G    G 
Sbjct: 804 LIVQQGDLARLPVDVVVNASNEDLKHYGGLAAALSKAAGPELQADCDQIVKREGRLLPGN 863

Query: 112 AKLTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINS 171
           A ++K   L    +IH VGP++           L    +  L LA++    S+    I+S
Sbjct: 864 ATISKAGKLPYHHVIHAVGPRWSGYEAPRCVYLLRRAVQLSLCLAEKYKYRSIAIPAISS 923

Query: 172 AKRGYPL 178
              G+PL
Sbjct: 924 GVFGFPL 930



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 33/142 (23%), Positives = 68/142 (47%), Gaps = 5/142 (3%)

Query: 55   KVVLWKGDVALLNCTAIVNTSNESLT-DKNPVSESIFMLAGPDLKEDLQKLK---GCRTG 110
            +++L K  V       +VN+    L   + P+S+S+   AGP+L+E+L  +        G
Sbjct: 1015 QMLLVKEGVQNAKTDVVVNSVPLDLVLSRGPLSKSLLEKAGPELQEELDTVGQGVAVSMG 1074

Query: 111  EAKLTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVIN 170
                T  +NL  R+++H V P++++   T++   +    R  +++ +  S+ S+ F  I 
Sbjct: 1075 TVLKTSSWNLDCRYVLHVVAPEWRNG-STSSLKIMEDIIRECMEITESLSLKSIAFPAIG 1133

Query: 171  SAKRGYPLEDATHIALRTVRRF 192
            +   G+P      + +  V +F
Sbjct: 1134 TGNLGFPKNIFAELIISEVFKF 1155



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 26/104 (25%), Positives = 49/104 (47%), Gaps = 11/104 (10%)

Query: 61   GDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNL 120
            GD+       IVN+++ S   K  VS++I   AG +++ +  +    R  +  +T G  L
Sbjct: 1234 GDITKEEADVIVNSTSNSFNLKAGVSKAILECAGQNVERECSQQAQQRKNDYIITGGGFL 1293

Query: 121  AARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSV 164
              + IIH +G            + + S   +VLQ  ++++ SS+
Sbjct: 1294 RCKNIIHVIG-----------GNDVKSSVSSVLQECEKKNYSSI 1326


>gi|8923920 H2A histone family, member Y2 [Homo sapiens]
          Length = 372

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 33/154 (21%), Positives = 71/154 (46%), Gaps = 8/154 (5%)

Query: 63  VALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCR----TGEAKLTKGF 118
           +  +    IV+ +   +  K  + +++    G +  E +++L+  +      EA +++  
Sbjct: 207 IGSMRVEGIVHPTTAEIDLKEDIGKALEKAGGKEFLETVKELRKSQGPLEVAEAAVSQSS 266

Query: 119 NLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPL 178
            LAA+F+IH   P++ S      E  L    +N L  A+++ + SV F    S +  +P 
Sbjct: 267 GLAAKFVIHCHIPQWGS---DKCEEQLEETIKNCLSAAEDKKLKSVAFPPFPSGRNCFPK 323

Query: 179 EDATHIALRTV-RRFLEIHGETIEKVVFAVSDLE 211
           + A  + L+ +   F +    +++ V F + D E
Sbjct: 324 QTAAQVTLKAISAHFDDSSASSLKNVYFLLFDSE 357


>gi|226371718 poly (ADP-ribose) polymerase family, member 9 isoform
           c [Homo sapiens]
          Length = 710

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 39/179 (21%), Positives = 76/179 (42%), Gaps = 8/179 (4%)

Query: 24  QDELNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVL--WKGDVALLNCTAIVNTSNESLTD 81
           Q++     T     QE   +S  ++ K +  ++ L  WK D+      A+VN +NE L  
Sbjct: 51  QNKFGCISTLVSPVQEGNSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLH 110

Query: 82  KNPVSESIFMLAGPDLKEDLQKLKG----CRTGEAKLTKGFNLAARFIIHTVGPKYKSRY 137
              ++ ++    G +++E+ ++          GE  +T    L  + IIH VGP++    
Sbjct: 111 GGGLALALVKAGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWD 170

Query: 138 RTAAESSLYSCYRNVLQ--LAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLE 194
           +      L     ++L   + K   + +V    ++S    +PL   T   + T+R  L+
Sbjct: 171 KQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQ 229



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 52/215 (24%), Positives = 91/215 (42%), Gaps = 23/215 (10%)

Query: 34  AEIFQEDTVRSPFLYNKDVNGKVVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLA 93
           +E+ QE T     +   ++  ++V  +G +       IVN+ N       PV++SI   A
Sbjct: 264 SELGQETTPSFNAMVVNNLTLQIV--QGHIEWQTADVIVNSVNPHDITVGPVAKSILQQA 321

Query: 94  GPDLKEDLQKLKGCRTGEAKL---TKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYR 150
           G ++K +    K  +   ++L   TKGFNL  ++I H +   + S +       L    +
Sbjct: 322 GVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL---WHSEF--PKPQILKHAMK 376

Query: 151 NVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLEIHGE---TIEKVVFAV 207
             L+   EQ+++S+ F  + +       E A  I    V  F + H +   T++ V+F  
Sbjct: 377 ECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQLTVKFVIFPT 436

Query: 208 S-------DLEEGTYQKLLPL---YFPRSLKEENR 232
                     E     K+L L     P+S +EE R
Sbjct: 437 DLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKR 471


>gi|226371716 poly (ADP-ribose) polymerase family, member 9 isoform
           b [Homo sapiens]
          Length = 819

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 39/179 (21%), Positives = 76/179 (42%), Gaps = 8/179 (4%)

Query: 24  QDELNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVL--WKGDVALLNCTAIVNTSNESLTD 81
           Q++     T     QE   +S  ++ K +  ++ L  WK D+      A+VN +NE L  
Sbjct: 51  QNKFGCISTLVSPVQEGNSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLH 110

Query: 82  KNPVSESIFMLAGPDLKEDLQKLKG----CRTGEAKLTKGFNLAARFIIHTVGPKYKSRY 137
              ++ ++    G +++E+ ++          GE  +T    L  + IIH VGP++    
Sbjct: 111 GGGLALALVKAGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWD 170

Query: 138 RTAAESSLYSCYRNVLQ--LAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLE 194
           +      L     ++L   + K   + +V    ++S    +PL   T   + T+R  L+
Sbjct: 171 KQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQ 229



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 52/215 (24%), Positives = 91/215 (42%), Gaps = 23/215 (10%)

Query: 34  AEIFQEDTVRSPFLYNKDVNGKVVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLA 93
           +E+ QE T     +   ++  ++V  +G +       IVN+ N       PV++SI   A
Sbjct: 264 SELGQETTPSFNAMVVNNLTLQIV--QGHIEWQTADVIVNSVNPHDITVGPVAKSILQQA 321

Query: 94  GPDLKEDLQKLKGCRTGEAKL---TKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYR 150
           G ++K +    K  +   ++L   TKGFNL  ++I H +   + S +       L    +
Sbjct: 322 GVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL---WHSEF--PKPQILKHAMK 376

Query: 151 NVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLEIHGE---TIEKVVFAV 207
             L+   EQ+++S+ F  + +       E A  I    V  F + H +   T++ V+F  
Sbjct: 377 ECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQLTVKFVIFPT 436

Query: 208 S-------DLEEGTYQKLLPL---YFPRSLKEENR 232
                     E     K+L L     P+S +EE R
Sbjct: 437 DLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKR 471


>gi|226371714 poly (ADP-ribose) polymerase family, member 9 isoform
           b [Homo sapiens]
          Length = 819

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 39/179 (21%), Positives = 76/179 (42%), Gaps = 8/179 (4%)

Query: 24  QDELNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVL--WKGDVALLNCTAIVNTSNESLTD 81
           Q++     T     QE   +S  ++ K +  ++ L  WK D+      A+VN +NE L  
Sbjct: 51  QNKFGCISTLVSPVQEGNSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLH 110

Query: 82  KNPVSESIFMLAGPDLKEDLQKLKG----CRTGEAKLTKGFNLAARFIIHTVGPKYKSRY 137
              ++ ++    G +++E+ ++          GE  +T    L  + IIH VGP++    
Sbjct: 111 GGGLALALVKAGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWD 170

Query: 138 RTAAESSLYSCYRNVLQ--LAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLE 194
           +      L     ++L   + K   + +V    ++S    +PL   T   + T+R  L+
Sbjct: 171 KQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQ 229



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 52/215 (24%), Positives = 91/215 (42%), Gaps = 23/215 (10%)

Query: 34  AEIFQEDTVRSPFLYNKDVNGKVVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLA 93
           +E+ QE T     +   ++  ++V  +G +       IVN+ N       PV++SI   A
Sbjct: 264 SELGQETTPSFNAMVVNNLTLQIV--QGHIEWQTADVIVNSVNPHDITVGPVAKSILQQA 321

Query: 94  GPDLKEDLQKLKGCRTGEAKL---TKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYR 150
           G ++K +    K  +   ++L   TKGFNL  ++I H +   + S +       L    +
Sbjct: 322 GVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL---WHSEF--PKPQILKHAMK 376

Query: 151 NVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLEIHGE---TIEKVVFAV 207
             L+   EQ+++S+ F  + +       E A  I    V  F + H +   T++ V+F  
Sbjct: 377 ECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQLTVKFVIFPT 436

Query: 208 S-------DLEEGTYQKLLPL---YFPRSLKEENR 232
                     E     K+L L     P+S +EE R
Sbjct: 437 DLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKR 471


>gi|226371712 poly (ADP-ribose) polymerase family, member 9 isoform
           b [Homo sapiens]
          Length = 819

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 39/179 (21%), Positives = 76/179 (42%), Gaps = 8/179 (4%)

Query: 24  QDELNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVL--WKGDVALLNCTAIVNTSNESLTD 81
           Q++     T     QE   +S  ++ K +  ++ L  WK D+      A+VN +NE L  
Sbjct: 51  QNKFGCISTLVSPVQEGNSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLH 110

Query: 82  KNPVSESIFMLAGPDLKEDLQKLKG----CRTGEAKLTKGFNLAARFIIHTVGPKYKSRY 137
              ++ ++    G +++E+ ++          GE  +T    L  + IIH VGP++    
Sbjct: 111 GGGLALALVKAGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWD 170

Query: 138 RTAAESSLYSCYRNVLQ--LAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLE 194
           +      L     ++L   + K   + +V    ++S    +PL   T   + T+R  L+
Sbjct: 171 KQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQ 229



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 52/215 (24%), Positives = 91/215 (42%), Gaps = 23/215 (10%)

Query: 34  AEIFQEDTVRSPFLYNKDVNGKVVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLA 93
           +E+ QE T     +   ++  ++V  +G +       IVN+ N       PV++SI   A
Sbjct: 264 SELGQETTPSFNAMVVNNLTLQIV--QGHIEWQTADVIVNSVNPHDITVGPVAKSILQQA 321

Query: 94  GPDLKEDLQKLKGCRTGEAKL---TKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYR 150
           G ++K +    K  +   ++L   TKGFNL  ++I H +   + S +       L    +
Sbjct: 322 GVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL---WHSEF--PKPQILKHAMK 376

Query: 151 NVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLEIHGE---TIEKVVFAV 207
             L+   EQ+++S+ F  + +       E A  I    V  F + H +   T++ V+F  
Sbjct: 377 ECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQLTVKFVIFPT 436

Query: 208 S-------DLEEGTYQKLLPL---YFPRSLKEENR 232
                     E     K+L L     P+S +EE R
Sbjct: 437 DLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKR 471


>gi|226371710 poly (ADP-ribose) polymerase family, member 9 isoform
           a [Homo sapiens]
          Length = 854

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 39/179 (21%), Positives = 76/179 (42%), Gaps = 8/179 (4%)

Query: 24  QDELNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVL--WKGDVALLNCTAIVNTSNESLTD 81
           Q++     T     QE   +S  ++ K +  ++ L  WK D+      A+VN +NE L  
Sbjct: 86  QNKFGCISTLVSPVQEGNSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLH 145

Query: 82  KNPVSESIFMLAGPDLKEDLQKLKG----CRTGEAKLTKGFNLAARFIIHTVGPKYKSRY 137
              ++ ++    G +++E+ ++          GE  +T    L  + IIH VGP++    
Sbjct: 146 GGGLALALVKAGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWD 205

Query: 138 RTAAESSLYSCYRNVLQ--LAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLE 194
           +      L     ++L   + K   + +V    ++S    +PL   T   + T+R  L+
Sbjct: 206 KQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQ 264



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 52/215 (24%), Positives = 91/215 (42%), Gaps = 23/215 (10%)

Query: 34  AEIFQEDTVRSPFLYNKDVNGKVVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLA 93
           +E+ QE T     +   ++  ++V  +G +       IVN+ N       PV++SI   A
Sbjct: 299 SELGQETTPSFNAMVVNNLTLQIV--QGHIEWQTADVIVNSVNPHDITVGPVAKSILQQA 356

Query: 94  GPDLKEDLQKLKGCRTGEAKL---TKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYR 150
           G ++K +    K  +   ++L   TKGFNL  ++I H +   + S +       L    +
Sbjct: 357 GVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL---WHSEF--PKPQILKHAMK 411

Query: 151 NVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLEIHGE---TIEKVVFAV 207
             L+   EQ+++S+ F  + +       E A  I    V  F + H +   T++ V+F  
Sbjct: 412 ECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQLTVKFVIFPT 471

Query: 208 S-------DLEEGTYQKLLPL---YFPRSLKEENR 232
                     E     K+L L     P+S +EE R
Sbjct: 472 DLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKR 506


>gi|226371706 poly (ADP-ribose) polymerase family, member 9 isoform
           a [Homo sapiens]
          Length = 854

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 39/179 (21%), Positives = 76/179 (42%), Gaps = 8/179 (4%)

Query: 24  QDELNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVL--WKGDVALLNCTAIVNTSNESLTD 81
           Q++     T     QE   +S  ++ K +  ++ L  WK D+      A+VN +NE L  
Sbjct: 86  QNKFGCISTLVSPVQEGNSKSLQVFRKMLTPRIELSVWKDDLTTHAVDAVVNAANEDLLH 145

Query: 82  KNPVSESIFMLAGPDLKEDLQKLKG----CRTGEAKLTKGFNLAARFIIHTVGPKYKSRY 137
              ++ ++    G +++E+ ++          GE  +T    L  + IIH VGP++    
Sbjct: 146 GGGLALALVKAGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWD 205

Query: 138 RTAAESSLYSCYRNVLQ--LAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLE 194
           +      L     ++L   + K   + +V    ++S    +PL   T   + T+R  L+
Sbjct: 206 KQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQ 264



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 52/215 (24%), Positives = 91/215 (42%), Gaps = 23/215 (10%)

Query: 34  AEIFQEDTVRSPFLYNKDVNGKVVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLA 93
           +E+ QE T     +   ++  ++V  +G +       IVN+ N       PV++SI   A
Sbjct: 299 SELGQETTPSFNAMVVNNLTLQIV--QGHIEWQTADVIVNSVNPHDITVGPVAKSILQQA 356

Query: 94  GPDLKEDLQKLKGCRTGEAKL---TKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYR 150
           G ++K +    K  +   ++L   TKGFNL  ++I H +   + S +       L    +
Sbjct: 357 GVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL---WHSEF--PKPQILKHAMK 411

Query: 151 NVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLEIHGE---TIEKVVFAV 207
             L+   EQ+++S+ F  + +       E A  I    V  F + H +   T++ V+F  
Sbjct: 412 ECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQLTVKFVIFPT 471

Query: 208 S-------DLEEGTYQKLLPL---YFPRSLKEENR 232
                     E     K+L L     P+S +EE R
Sbjct: 472 DLEIYKAFSSEMAKRSKMLSLNNYSVPQSTREEKR 506


>gi|109826564 neurofibromin isoform 1 [Homo sapiens]
          Length = 2839

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 36/151 (23%), Positives = 58/151 (38%), Gaps = 3/151 (1%)

Query: 329  EDLSDIASLKALYQTGVDNCGRTVMVVVGRNIPVTLIDMDKALLYFIHVMDHIAVKEYVL 388
            E+   + +L   YQ G    G  +   V R      I+ D  + + +  +     K Y +
Sbjct: 1582 EEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQINGDLLIYHVLLTLKPYYAKPYEI 1641

Query: 389  VYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRNLKAVYFVHPTFRSKVSTWFFTTFSVSGL 448
            V   T T   N   +DFL K + V       N+ AVY  +     +  T +     ++GL
Sbjct: 1642 VVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIYNCNSWVREYTKYHERL-LTGL 1700

Query: 449  K--DKIHHVDSLHQLFSAISPEQIDFPPFVL 477
            K   ++  +D   +L   I  EQ   P   L
Sbjct: 1701 KGSKRLVFIDCPGKLAEHIEHEQQKLPAATL 1731


>gi|4557793 neurofibromin isoform 2 [Homo sapiens]
          Length = 2818

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 36/151 (23%), Positives = 58/151 (38%), Gaps = 3/151 (1%)

Query: 329  EDLSDIASLKALYQTGVDNCGRTVMVVVGRNIPVTLIDMDKALLYFIHVMDHIAVKEYVL 388
            E+   + +L   YQ G    G  +   V R      I+ D  + + +  +     K Y +
Sbjct: 1561 EEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQINGDLLIYHVLLTLKPYYAKPYEI 1620

Query: 389  VYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRNLKAVYFVHPTFRSKVSTWFFTTFSVSGL 448
            V   T T   N   +DFL K + V       N+ AVY  +     +  T +     ++GL
Sbjct: 1621 VVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIYNCNSWVREYTKYHERL-LTGL 1679

Query: 449  K--DKIHHVDSLHQLFSAISPEQIDFPPFVL 477
            K   ++  +D   +L   I  EQ   P   L
Sbjct: 1680 KGSKRLVFIDCPGKLAEHIEHEQQKLPAATL 1710


>gi|165377137 poly (ADP-ribose) polymerase family, member 15 isoform
           1 [Homo sapiens]
          Length = 678

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 5/124 (4%)

Query: 58  LWKGDVALLNCTAIVNTSNESLT-DKNPVSESIFMLAGPDLKEDLQKLKGC---RTGEAK 113
           L  GDV  +    IVN+   +L     P+S +    AGP L+++L   +     + G   
Sbjct: 93  LISGDVLYIWADVIVNSVPMNLQLGGGPLSRAFLQKAGPMLQKELDDRRRETEEKVGNIF 152

Query: 114 LTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAK 173
           +T G NL  + ++H V P + +   T+ +  + +  +  L   +  S SS+ F +I +  
Sbjct: 153 MTSGCNLDCKAVLHAVAPYWNNGAETSWQ-IMANIIKKCLTTVEVLSFSSITFPMIGTGS 211

Query: 174 RGYP 177
             +P
Sbjct: 212 LQFP 215



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 27/115 (23%), Positives = 47/115 (40%), Gaps = 11/115 (9%)

Query: 61  GDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNL 120
           GD+A      IVN++  +   K+ VS +I   AG  ++ +   L      +  +T G  L
Sbjct: 311 GDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFIITPGGCL 370

Query: 121 AARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRG 175
             + IIH  G K            +     +VL+  +++  +SV    I +   G
Sbjct: 371 KCKIIIHVPGGK-----------DVRKTVTSVLEECEQRKYTSVSLPAIGTGNAG 414


>gi|4506541 retinaldehyde binding protein 1 [Homo sapiens]
          Length = 317

 Score = 33.1 bits (74), Expect = 0.60
 Identities = 33/155 (21%), Positives = 61/155 (39%), Gaps = 25/155 (16%)

Query: 346 DNCGRTVMVVVGRNIPVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYN------ 399
           D  GR VM+    N     I  D+ L  +  +++ +   E   +    +   +       
Sbjct: 152 DKYGRVVMLFNIENWQSQEITFDEILQAYCFILEKLLENEETQINGFCIIENFKGFTMQQ 211

Query: 400 --HLDSDFLKKLYDVVDVKYKRNLKAVYFVHPTFRSKVSTWFFTT-------FSVSGLKD 450
              L +  L+K+ D++   +    KA++F+H         W+FTT       F  S L +
Sbjct: 212 AASLRTSDLRKMVDMLQDSFPARFKAIHFIH-------QPWYFTTTYNVVKPFLKSKLLE 264

Query: 451 KIH-HVDSLHQLFSAISPEQI--DFPPFVLEYDAR 482
           ++  H D L   +  I    +  DF   + +YD +
Sbjct: 265 RVFVHGDDLSGFYQEIDENILPSDFGGTLPKYDGK 299


>gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]
          Length = 888

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 34/130 (26%), Positives = 60/130 (46%), Gaps = 12/130 (9%)

Query: 207 VSDLEEGTYQKLLPLYFPRSLKEENRSLPYLPADIGNAEGEPVVPERQIR-ISEKPGAPE 265
           VS+ ++   ++  PL    S++E N    Y   D  + +  P V +R+ R  S+K G+  
Sbjct: 177 VSEPKKWNLRRNRPLLDFVSMEELNDMDDYDSED--DNDWRPTVVKRKGRSASQKEGSDG 234

Query: 266 DNQEEEDEGLGVDLSFIG-----SHAFARMEGDIDKQRKLILQGQLSEAALQKQHQRNYN 320
           DN+++EDEG G D           H+    EG   K++  +    LS  +   +   N +
Sbjct: 235 DNEDDEDEGSGSDEDENDEGNDEDHSSPASEGGCKKKKSKV----LSRNSADDEELTNDS 290

Query: 321 RWLCQARSED 330
             L Q++S +
Sbjct: 291 LTLSQSKSNE 300


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,765,708
Number of Sequences: 37866
Number of extensions: 828491
Number of successful extensions: 2641
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 2582
Number of HSP's gapped (non-prelim): 65
length of query: 497
length of database: 18,247,518
effective HSP length: 106
effective length of query: 391
effective length of database: 14,233,722
effective search space: 5565385302
effective search space used: 5565385302
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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