Guide to the Human Genome
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Search of human proteins with 8922479

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|8922479 armadillo repeat-containing protein [Homo sapiens]
         (282 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|8922479 armadillo repeat-containing protein [Homo sapiens]         553   e-158
gi|219283155 apoptosis inhibitor 5 isoform c [Homo sapiens]            31   1.4  
gi|153945765 mitogen-activated protein kinase kinase kinase 1 [H...    31   1.4  
gi|239757861 PREDICTED: similar to armadillo repeat containing, ...    31   1.4  
gi|189011568 adenomatous polyposis coli [Homo sapiens]                 30   1.8  
gi|189011566 adenomatous polyposis coli [Homo sapiens]                 30   1.8  
gi|53759122 adenomatous polyposis coli [Homo sapiens]                  30   1.8  
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [...    30   2.4  
gi|122937492 SET domain containing 5 [Homo sapiens]                    30   2.4  
gi|170784859 serine/threonine kinase 31 isoform b [Homo sapiens]       30   3.1  
gi|14602443 serine/threonine kinase 31 isoform a [Homo sapiens]        30   3.1  
gi|170784856 serine/threonine kinase 31 isoform b [Homo sapiens]       30   3.1  
gi|219283152 apoptosis inhibitor 5 isoform a [Homo sapiens]            29   4.1  
gi|5729730 apoptosis inhibitor 5 isoform b [Homo sapiens]              29   4.1  
gi|6912678 sperm associated antigen 6 isoform 1 [Homo sapiens]         28   6.9  
gi|27262641 sperm associated antigen 6 isoform 2 [Homo sapiens]        28   6.9  
gi|50811889 centrosomal protein 192kDa [Homo sapiens]                  28   6.9  
gi|113722133 senataxin [Homo sapiens]                                  28   9.0  

>gi|8922479 armadillo repeat-containing protein [Homo sapiens]
          Length = 282

 Score =  553 bits (1425), Expect = e-158
 Identities = 282/282 (100%), Positives = 282/282 (100%)

Query: 1   MNSSTSTMSEEPDALSVVNQLRDLAADPLNRRAIVQDQGCLPGLILFMDHPNPPVVHSAL 60
           MNSSTSTMSEEPDALSVVNQLRDLAADPLNRRAIVQDQGCLPGLILFMDHPNPPVVHSAL
Sbjct: 1   MNSSTSTMSEEPDALSVVNQLRDLAADPLNRRAIVQDQGCLPGLILFMDHPNPPVVHSAL 60

Query: 61  LALRYLAECRANREKMKGELGMMLSLQNVIQKTTTPGETKLLASEIYDILQSSNMADGDS 120
           LALRYLAECRANREKMKGELGMMLSLQNVIQKTTTPGETKLLASEIYDILQSSNMADGDS
Sbjct: 61  LALRYLAECRANREKMKGELGMMLSLQNVIQKTTTPGETKLLASEIYDILQSSNMADGDS 120

Query: 121 FNEMNSRRRKAQFFLGTTNKRAKTVVLHIDGLDDTSRRNLCEEALLKIKGVISFTFQMAV 180
           FNEMNSRRRKAQFFLGTTNKRAKTVVLHIDGLDDTSRRNLCEEALLKIKGVISFTFQMAV
Sbjct: 121 FNEMNSRRRKAQFFLGTTNKRAKTVVLHIDGLDDTSRRNLCEEALLKIKGVISFTFQMAV 180

Query: 181 QRCVVRIRSDLKAEALASAIASTKVMKAQQVVKSESGEEMLVPFQDTPVEVEQNTELPDY 240
           QRCVVRIRSDLKAEALASAIASTKVMKAQQVVKSESGEEMLVPFQDTPVEVEQNTELPDY
Sbjct: 181 QRCVVRIRSDLKAEALASAIASTKVMKAQQVVKSESGEEMLVPFQDTPVEVEQNTELPDY 240

Query: 241 LPEDESPTKEQDKAVSRVGSHPEGGASWLSTAANFLSRSFYW 282
           LPEDESPTKEQDKAVSRVGSHPEGGASWLSTAANFLSRSFYW
Sbjct: 241 LPEDESPTKEQDKAVSRVGSHPEGGASWLSTAANFLSRSFYW 282


>gi|219283155 apoptosis inhibitor 5 isoform c [Homo sapiens]
          Length = 450

 Score = 30.8 bits (68), Expect = 1.4
 Identities = 29/124 (23%), Positives = 54/124 (43%), Gaps = 20/124 (16%)

Query: 119 DSFNEMNSRRRKA-----QFFLGTTNKRAKTVVLHIDGLDDTSRRNLCEEALLKI----- 168
           D+  ++   RR+A     QF  G    R   ++  +   DD++  NL   ALL I     
Sbjct: 16  DATEQVGQIRRQAIKELPQFATGENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDA 75

Query: 169 KGVISFTFQMAVQ-------RCVVRIRSDLKA---EALASAIASTKVMKAQQVVKSESGE 218
           KG +   F   +Q       R +  + + LK    E L   +    + ++++V++  +GE
Sbjct: 76  KGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGE 135

Query: 219 EMLV 222
           E ++
Sbjct: 136 EFVL 139


>gi|153945765 mitogen-activated protein kinase kinase kinase 1 [Homo
            sapiens]
          Length = 1512

 Score = 30.8 bits (68), Expect = 1.4
 Identities = 22/74 (29%), Positives = 39/74 (52%), Gaps = 4/74 (5%)

Query: 181  QRCVVRIRSDLKAEALASAIASTKVMKAQQVVKS---ESGEEMLVPFQDTPVEVEQNTEL 237
            Q+C  ++ ++ + EALA A+A +    A  +V     E+GE++++  QDTP  +  +T+ 
Sbjct: 1175 QKCKEKMEAE-EEEALAIAMAMSASQDALPIVPQLQVENGEDIIIIQQDTPETLPGHTKA 1233

Query: 238  PDYLPEDESPTKEQ 251
                 ED    K Q
Sbjct: 1234 KQPYREDTEWLKGQ 1247


>gi|239757861 PREDICTED: similar to armadillo repeat containing,
            X-linked 4 [Homo sapiens]
          Length = 2382

 Score = 30.8 bits (68), Expect = 1.4
 Identities = 19/76 (25%), Positives = 35/76 (46%)

Query: 8    MSEEPDALSVVNQLRDLAADPLNRRAIVQDQGCLPGLILFMDHPNPPVVHSALLALRYLA 67
            M+E+P    + N     +AD      +V++ G +  +   +++P P V   AL AL  ++
Sbjct: 2144 MTEDPSVHEIANNALYNSADYSYSHEVVRNVGGISVIESLLNNPYPSVRQKALNALNNIS 2203

Query: 68   ECRANREKMKGELGMM 83
                N  K+K  L  +
Sbjct: 2204 VAAENHRKVKTYLNQV 2219


>gi|189011568 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 30.4 bits (67), Expect = 1.8
 Identities = 28/136 (20%), Positives = 60/136 (44%), Gaps = 7/136 (5%)

Query: 3   SSTSTMSEEPDALSVVNQLRDLAADPLNRRAIVQDQGCLPGLILFMDHPNPPVVHSALLA 62
           S T+T++       ++  +  L A   + R I+++  CL  L+  +   +  +V +A   
Sbjct: 624 SQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGT 683

Query: 63  LRYLAECRANREKMKGELGMMLSLQNVI---QKTTTPGET----KLLASEIYDILQSSNM 115
           L  L+      ++   ++G +  L+N+I    K    G       L+A+       ++ M
Sbjct: 684 LWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYKDANIM 743

Query: 116 ADGDSFNEMNSRRRKA 131
           + G S   ++ R++KA
Sbjct: 744 SPGSSLPSLHVRKQKA 759


>gi|189011566 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 30.4 bits (67), Expect = 1.8
 Identities = 28/136 (20%), Positives = 60/136 (44%), Gaps = 7/136 (5%)

Query: 3   SSTSTMSEEPDALSVVNQLRDLAADPLNRRAIVQDQGCLPGLILFMDHPNPPVVHSALLA 62
           S T+T++       ++  +  L A   + R I+++  CL  L+  +   +  +V +A   
Sbjct: 624 SQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGT 683

Query: 63  LRYLAECRANREKMKGELGMMLSLQNVI---QKTTTPGET----KLLASEIYDILQSSNM 115
           L  L+      ++   ++G +  L+N+I    K    G       L+A+       ++ M
Sbjct: 684 LWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYKDANIM 743

Query: 116 ADGDSFNEMNSRRRKA 131
           + G S   ++ R++KA
Sbjct: 744 SPGSSLPSLHVRKQKA 759


>gi|53759122 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 30.4 bits (67), Expect = 1.8
 Identities = 28/136 (20%), Positives = 60/136 (44%), Gaps = 7/136 (5%)

Query: 3   SSTSTMSEEPDALSVVNQLRDLAADPLNRRAIVQDQGCLPGLILFMDHPNPPVVHSALLA 62
           S T+T++       ++  +  L A   + R I+++  CL  L+  +   +  +V +A   
Sbjct: 624 SQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGT 683

Query: 63  LRYLAECRANREKMKGELGMMLSLQNVI---QKTTTPGET----KLLASEIYDILQSSNM 115
           L  L+      ++   ++G +  L+N+I    K    G       L+A+       ++ M
Sbjct: 684 LWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYKDANIM 743

Query: 116 ADGDSFNEMNSRRRKA 131
           + G S   ++ R++KA
Sbjct: 744 SPGSSLPSLHVRKQKA 759


>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein
           [Homo sapiens]
          Length = 3969

 Score = 30.0 bits (66), Expect = 2.4
 Identities = 40/160 (25%), Positives = 69/160 (43%), Gaps = 13/160 (8%)

Query: 106 IYDILQSSNMADGDSFNEMNSRRRKAQFFLGTTNKRAKTVVLHIDGLDDTSRRNLCEEAL 165
           ++  L  S    GD   + +S+  + +     T    K  + H   + +  + N  E++L
Sbjct: 195 VFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNK-EDSL 253

Query: 166 LKIKGVISFTFQMAVQRCVVRIRSDLKAEALASAIASTKVM---KAQQVVKSESGEEMLV 222
            KIK   S TFQ A +  + ++R+  K   L S   + K+    K  Q+V+   G     
Sbjct: 254 KKIKRTPSATFQQATK--IKKLRAG-KLSPLKSKFKTGKLQIGRKGVQIVR-RRGRPPST 309

Query: 223 PFQDTPVEVEQNTEL--PDYLPEDES---PTKEQDKAVSR 257
               TP  +  N+EL  P  + +D+    P  ++DK V R
Sbjct: 310 ERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVR 349


>gi|122937492 SET domain containing 5 [Homo sapiens]
          Length = 1442

 Score = 30.0 bits (66), Expect = 2.4
 Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 3/57 (5%)

Query: 186 RIRSDLKAEALASA---IASTKVMKAQQVVKSESGEEMLVPFQDTPVEVEQNTELPD 239
           R R D K EA+  A   +   K  + Q + +S S  E+     +TPV  E  TE P+
Sbjct: 508 RTREDRKVEAIMHAFENLEKRKKRRDQPLEQSNSDVEITTTTSETPVGEETKTEAPE 564


>gi|170784859 serine/threonine kinase 31 isoform b [Homo sapiens]
          Length = 996

 Score = 29.6 bits (65), Expect = 3.1
 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 3/62 (4%)

Query: 196 LASAIASTKVMKAQQVVKSESGEEMLVPFQDTPVEVEQNTELPDYLPEDESPTKEQDKAV 255
           L S I     M A+QV+ +E     L+P + +    E++TE   Y  E+E  T+  DK +
Sbjct: 928 LCSLICYRSSMTAEQVLNAEC---FLMPKEQSVPNPEKDTEYTLYKKEEEIKTENLDKCM 984

Query: 256 SR 257
            +
Sbjct: 985 EK 986


>gi|14602443 serine/threonine kinase 31 isoform a [Homo sapiens]
          Length = 1019

 Score = 29.6 bits (65), Expect = 3.1
 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 3/62 (4%)

Query: 196  LASAIASTKVMKAQQVVKSESGEEMLVPFQDTPVEVEQNTELPDYLPEDESPTKEQDKAV 255
            L S I     M A+QV+ +E     L+P + +    E++TE   Y  E+E  T+  DK +
Sbjct: 951  LCSLICYRSSMTAEQVLNAEC---FLMPKEQSVPNPEKDTEYTLYKKEEEIKTENLDKCM 1007

Query: 256  SR 257
             +
Sbjct: 1008 EK 1009


>gi|170784856 serine/threonine kinase 31 isoform b [Homo sapiens]
          Length = 996

 Score = 29.6 bits (65), Expect = 3.1
 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 3/62 (4%)

Query: 196 LASAIASTKVMKAQQVVKSESGEEMLVPFQDTPVEVEQNTELPDYLPEDESPTKEQDKAV 255
           L S I     M A+QV+ +E     L+P + +    E++TE   Y  E+E  T+  DK +
Sbjct: 928 LCSLICYRSSMTAEQVLNAEC---FLMPKEQSVPNPEKDTEYTLYKKEEEIKTENLDKCM 984

Query: 256 SR 257
            +
Sbjct: 985 EK 986


>gi|219283152 apoptosis inhibitor 5 isoform a [Homo sapiens]
          Length = 524

 Score = 29.3 bits (64), Expect = 4.1
 Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 15/106 (14%)

Query: 132 QFFLGTTNKRAKTVVLHIDGLDDTSRRNLCEEALLKI-----KGVISFTFQMAVQ----- 181
           QF  G    R   ++  +   DD++  NL   ALL I     KG +   F   +Q     
Sbjct: 88  QFATGENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIV 147

Query: 182 --RCVVRIRSDLKA---EALASAIASTKVMKAQQVVKSESGEEMLV 222
             R +  + + LK    E L   +    + ++++V++  +GEE ++
Sbjct: 148 RERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGEEFVL 193


>gi|5729730 apoptosis inhibitor 5 isoform b [Homo sapiens]
          Length = 504

 Score = 29.3 bits (64), Expect = 4.1
 Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 15/106 (14%)

Query: 132 QFFLGTTNKRAKTVVLHIDGLDDTSRRNLCEEALLKI-----KGVISFTFQMAVQ----- 181
           QF  G    R   ++  +   DD++  NL   ALL I     KG +   F   +Q     
Sbjct: 88  QFATGENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIV 147

Query: 182 --RCVVRIRSDLKA---EALASAIASTKVMKAQQVVKSESGEEMLV 222
             R +  + + LK    E L   +    + ++++V++  +GEE ++
Sbjct: 148 RERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGEEFVL 193


>gi|6912678 sperm associated antigen 6 isoform 1 [Homo sapiens]
          Length = 509

 Score = 28.5 bits (62), Expect = 6.9
 Identities = 26/86 (30%), Positives = 42/86 (48%), Gaps = 2/86 (2%)

Query: 28  PLNRRAIVQDQGCLPGLILFMDHPNPPVVHSALLALRYLAECRANREKMKGELGMMLSLQ 87
           P   +AIV D G L  L++ ++  +P V  +A  ALRY+A   A   +   + G +  L 
Sbjct: 115 PQLAQAIV-DCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLV 173

Query: 88  NVIQKTTTPGETKLLASEIYDILQSS 113
             IQ+       ++ AS + DI + S
Sbjct: 174 LCIQEPEI-ALKRIAASALSDIAKHS 198


>gi|27262641 sperm associated antigen 6 isoform 2 [Homo sapiens]
          Length = 458

 Score = 28.5 bits (62), Expect = 6.9
 Identities = 26/86 (30%), Positives = 42/86 (48%), Gaps = 2/86 (2%)

Query: 28  PLNRRAIVQDQGCLPGLILFMDHPNPPVVHSALLALRYLAECRANREKMKGELGMMLSLQ 87
           P   +AIV D G L  L++ ++  +P V  +A  ALRY+A   A   +   + G +  L 
Sbjct: 115 PQLAQAIV-DCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLV 173

Query: 88  NVIQKTTTPGETKLLASEIYDILQSS 113
             IQ+       ++ AS + DI + S
Sbjct: 174 LCIQEPEI-ALKRIAASALSDIAKHS 198


>gi|50811889 centrosomal protein 192kDa [Homo sapiens]
          Length = 1941

 Score = 28.5 bits (62), Expect = 6.9
 Identities = 17/57 (29%), Positives = 32/57 (56%), Gaps = 1/57 (1%)

Query: 170 GVISFTFQMAVQRCVVRIRSDLKAEALASAIASTKVMKAQQVVKSESGEEMLVPFQD 226
           GV   TF +A   C     + ++AEALAS +  T + ++  V++ E+ ++ ++ F D
Sbjct: 858 GVFRCTFSVASWPCSTDAETIVQAEALASTVTLTAIAES-PVIEVETEKKDVLDFGD 913


>gi|113722133 senataxin [Homo sapiens]
          Length = 2677

 Score = 28.1 bits (61), Expect = 9.0
 Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 14/79 (17%)

Query: 42  PGLILFMDHPNPPVVHSALLALRYLAECRANREKMKG------------ELGMMLSLQNV 89
           PG+ LF+ HPN  V   A+L  R L   + +R+                ELG++ S    
Sbjct: 154 PGIYLFLVHPNEMVRRWAILTARNLG--KVDRDDYYDLQEVLLCLFKVIELGLLESPDIY 211

Query: 90  IQKTTTPGETKLLASEIYD 108
                  G+  LL S +YD
Sbjct: 212 TSSVLEKGKLILLPSHMYD 230


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.129    0.360 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,643,279
Number of Sequences: 37866
Number of extensions: 374040
Number of successful extensions: 1197
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 1189
Number of HSP's gapped (non-prelim): 24
length of query: 282
length of database: 18,247,518
effective HSP length: 101
effective length of query: 181
effective length of database: 14,423,052
effective search space: 2610572412
effective search space used: 2610572412
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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