Search of human proteins with 8922256

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|8922256 estrogen-related receptor beta like 1 [Homo sapiens]
         (429 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|8922256 estrogen-related receptor beta like 1 [Homo sapiens]       854   0.0  
gi|71061468 centromere protein E [Homo sapiens]                        64   3e-10
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...    54   2e-07
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]     54   3e-07
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]                   52   8e-07
gi|118498362 kinectin 1 isoform b [Homo sapiens]                       52   1e-06
gi|118498368 kinectin 1 isoform c [Homo sapiens]                       52   1e-06
gi|156104908 myosin heavy chain 6 [Homo sapiens]                       51   2e-06
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...    51   2e-06
gi|118498356 kinectin 1 isoform a [Homo sapiens]                       50   5e-06
gi|33620775 kinectin 1 isoform a [Homo sapiens]                        50   5e-06
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    49   7e-06
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    49   7e-06
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    49   7e-06
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    49   7e-06
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]           49   9e-06
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]           49   9e-06
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]           49   9e-06
gi|55770834 centromere protein F [Homo sapiens]                        49   9e-06
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo...    49   1e-05
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo...    49   1e-05
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...    47   3e-05
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    47   4e-05
gi|16262452 cingulin [Homo sapiens]                                    46   7e-05
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo...    46   7e-05
gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 ...    46   7e-05
gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 ...    46   7e-05
gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]        45   1e-04
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    45   1e-04
gi|154354990 ankyrin repeat domain 26 [Homo sapiens]                   45   1e-04

>gi|8922256 estrogen-related receptor beta like 1 [Homo sapiens]
          Length = 429

 Score =  854 bits (2206), Expect = 0.0
 Identities = 429/429 (100%), Positives = 429/429 (100%)

Query: 1   MTAALAVVTTSGLEDGVPRSRGEGTGEVVLERGPGAAYHMFVVMEDLVEKLKLLRYEEEF 60
           MTAALAVVTTSGLEDGVPRSRGEGTGEVVLERGPGAAYHMFVVMEDLVEKLKLLRYEEEF
Sbjct: 1   MTAALAVVTTSGLEDGVPRSRGEGTGEVVLERGPGAAYHMFVVMEDLVEKLKLLRYEEEF 60

Query: 61  LRKSNLKAPSRHYFALPTNPGEQFYMFCTLAAWLINKAGRPFEQPQEYDDPNATISNILS 120
           LRKSNLKAPSRHYFALPTNPGEQFYMFCTLAAWLINKAGRPFEQPQEYDDPNATISNILS
Sbjct: 61  LRKSNLKAPSRHYFALPTNPGEQFYMFCTLAAWLINKAGRPFEQPQEYDDPNATISNILS 120

Query: 121 ELRSFGRTADFPPSKLKSGYGEHVCYVLDCFAEEALKYIGFTWKRPIYPVEELEEESVAE 180
           ELRSFGRTADFPPSKLKSGYGEHVCYVLDCFAEEALKYIGFTWKRPIYPVEELEEESVAE
Sbjct: 121 ELRSFGRTADFPPSKLKSGYGEHVCYVLDCFAEEALKYIGFTWKRPIYPVEELEEESVAE 180

Query: 181 DDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDILESTTDAAEWS 240
           DDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDILESTTDAAEWS
Sbjct: 181 DDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDILESTTDAAEWS 240

Query: 241 LEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLHNEITRTLEKI 300
           LEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLHNEITRTLEKI
Sbjct: 241 LEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLHNEITRTLEKI 300

Query: 301 SSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEM 360
           SSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEM
Sbjct: 301 SSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEM 360

Query: 361 EEKGSSMTDGAPLVKIKQSLTKLKQETVEMDIRIGIVEHTLLQSKLKEKSNMTRNMHATV 420
           EEKGSSMTDGAPLVKIKQSLTKLKQETVEMDIRIGIVEHTLLQSKLKEKSNMTRNMHATV
Sbjct: 361 EEKGSSMTDGAPLVKIKQSLTKLKQETVEMDIRIGIVEHTLLQSKLKEKSNMTRNMHATV 420

Query: 421 IPEPATGFY 429
           IPEPATGFY
Sbjct: 421 IPEPATGFY 429


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 58/235 (24%), Positives = 113/235 (48%), Gaps = 15/235 (6%)

Query: 192  EEFVEEETDNEENFIDLNVLKAQTYHLDMNE---TAKQEDILESTTDAAEWSLEVERVLP 248
            +E  E +  N EN    N+   Q  H ++ E     K+ D L S     E +L+VER   
Sbjct: 1650 KEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSV----EETLKVER--D 1703

Query: 249  QLKVTIR---TDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLHNEITRTLEKISSREK 305
            QLK  +R   T + + +  +  +H H    +  + + +G + +  NEI+   + +     
Sbjct: 1704 QLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSND 1763

Query: 306  YINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGS 365
             +  Q   + +E R A   L E +E   +  G V+E+T  LS + ++LE    +++EK  
Sbjct: 1764 ALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQ 1823

Query: 366  SM-TDGAPLVKIKQSLTKLKQETVEMD-IRIGIVEHTLLQSKLK-EKSNMTRNMH 417
             +  +   L+ +K+ + + +++  EM+ ++  I + +L  SKL+ E  N+ + +H
Sbjct: 1824 ELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLH 1878



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 55/247 (22%), Positives = 110/247 (44%), Gaps = 22/247 (8%)

Query: 182 DAELTLNKVDEEFVEEETDNEENFI--DLNVLKAQTYHLDMNETAKQEDILESTTDAAEW 239
           D +  LNK   E  E E   EE  +  +L  L ++   L      K E++   T++  + 
Sbjct: 724 DLQKELNK---EVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKL 780

Query: 240 SLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLHNEITRTLEK 299
             EV     +++  +    K      D +   +S  +S  +E + F   LH +  +  + 
Sbjct: 781 FSEVVHKESRVQGLLEEIGKT----KDDLATTQSNYKSTDQEFQNF-KTLHMDFEQKYKM 835

Query: 300 ISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQE 359
           +    + +N ++ NL +E +   + L   K         + E+TR + E + E+E++K++
Sbjct: 836 VLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQ 895

Query: 360 MEEKGSSMTD---GAPLV--KIKQSLTKLKQETVEMDIRIGIVEHTLLQSKLK-EKSNMT 413
           +E + S++        L+  K++Q+L ++K  T E D      +   LQ  L+ E+  + 
Sbjct: 896 LENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKD------DLKQLQESLQIERDQLK 949

Query: 414 RNMHATV 420
            ++H TV
Sbjct: 950 SDIHDTV 956



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 55/256 (21%), Positives = 116/256 (45%), Gaps = 29/256 (11%)

Query: 171  EELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDIL 230
            E+ ++ S  + D E +  K+ E+ ++E   NE   I L          D+NET K+   +
Sbjct: 1799 EKTDKLSNMQKDLENSNAKLQEK-IQELKANEHQLITLKK--------DVNETQKKVSEM 1849

Query: 231  ESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLH 290
            E      +     ++ L   K+ I   N        ++H++   ++S +KE     D L 
Sbjct: 1850 EQLKKQIK-----DQSLTLSKLEIENLNL-----AQKLHENLEEMKSVMKER----DNLR 1895

Query: 291  N-EITRTLEKISSREKYINNQLENLV--QEYRAAQAQLSEAKERYQQGNGGVTERTRLLS 347
              E T  LE+   +E     +  +L   QE + A+    E KE   +    ++E+T  +S
Sbjct: 1896 RVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQIS 1955

Query: 348  EVMEELEKVKQEMEEKGSSM-TDGAPLVKIKQSLTKLKQETVEMD--IRIGIVEHTLLQS 404
            ++ ++L+K K E+++K   +      L+++K+ +    ++  EM+   +    ++  +QS
Sbjct: 1956 DIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQS 2015

Query: 405  KLKEKSNMTRNMHATV 420
               +   +T+ +H ++
Sbjct: 2016 VRMDNFQLTKKLHESL 2031



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 48/238 (20%), Positives = 99/238 (41%), Gaps = 27/238 (11%)

Query: 192  EEFVEEETDNEENFIDLNVLKAQTYHLDMN-ETAKQEDILESTTDAAEWSLEVERVLPQL 250
            +E  E+  + +E   ++  LK Q  + D   +T ++E  L   T+  + +LE  + L Q 
Sbjct: 873  QELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTL--ITEKLQQTLEEVKTLTQE 930

Query: 251  KVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLHNEITRTLEKISSREKYINNQ 310
            K  ++   +  +I  DQ+       +S + +T         ++   LE +   ++ IN  
Sbjct: 931  KDDLKQLQESLQIERDQL-------KSDIHDTVNMNIDTQEQLRNALESLKQHQETINTL 983

Query: 311  LENLVQEYRA---AQAQLSEAKERYQQGNGGVTERTRLLS-------------EVMEELE 354
               + +E       +    E K+ +QQ   G+ ++  L +             E++E+  
Sbjct: 984  KSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQR 1043

Query: 355  KVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQETVEMDIRIGIVEHTLLQSKLKEKSNM 412
            K+   ++EK         ++  K+ L    +E +EM I     E  LL  +LK++  +
Sbjct: 1044 KIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIE-NQEELRLLGDELKKQQEI 1100



 Score = 37.0 bits (84), Expect = 0.034
 Identities = 58/302 (19%), Positives = 116/302 (38%), Gaps = 55/302 (18%)

Query: 170  VEELEEESVAEDDA-----ELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETA 224
            +E L E+S  +D       E+   +++E+F E + + +    + + LK     L++    
Sbjct: 1308 LELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQ 1367

Query: 225  KQEDILESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRS----------- 273
             +E I E+     E   + E+ L   +     DN+  +I V +M Q +            
Sbjct: 1368 LKEHIRETLAKIQESQSKQEQSLNMKE----KDNETTKI-VSEMEQFKPKDSALLRIEIE 1422

Query: 274  --GIESALKETKGFLDKLHNE---ITRTLEKISSREKYINNQLENLV-------QEYRAA 321
              G+   L+E+   +  +  E   + R  E + S    +   ++ +V       +E + A
Sbjct: 1423 MLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVA 1482

Query: 322  QAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQ--- 378
               L E +E   +    ++E+   +S + ++LE +  +++ K   + +      IKQ   
Sbjct: 1483 HCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISE 1542

Query: 379  ------SLTKLKQETVEMDIRIGIVEHTLL-------------QSKLKEKSNMTRNMHAT 419
                   L + K+     D  +  +E  +L             Q  +KEK  M R   A 
Sbjct: 1543 VQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEAL 1602

Query: 420  VI 421
             I
Sbjct: 1603 QI 1604



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 37/193 (19%), Positives = 87/193 (45%), Gaps = 9/193 (4%)

Query: 171  EELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTY--HLDMNETAKQED 228
            E++ E+++   D +  L+K  +E  ++  + ++  + L  +K      H  +NE  +   
Sbjct: 1945 EKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQ--- 2001

Query: 229  ILESTTDAAEWSLEVERVLP-QLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLD 287
             L+   +A   S++  R+   QL   +    ++ RI   +  + R   ES   E   F+ 
Sbjct: 2002 -LKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIA 2060

Query: 288  KLHNEITRTLE--KISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRL 345
             L   I R  +  ++   ++ +++  ++L +  R   +++ E  +RY + +       RL
Sbjct: 2061 TLREMIARDRQNHQVKPEKRLLSDGQQHLTESLREKCSRIKELLKRYSEMDDHYECLNRL 2120

Query: 346  LSEVMEELEKVKQ 358
              ++ +E+E  K+
Sbjct: 2121 SLDLEKEIEFQKE 2133



 Score = 30.0 bits (66), Expect = 4.2
 Identities = 34/195 (17%), Positives = 82/195 (42%), Gaps = 24/195 (12%)

Query: 180  EDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDILESTTDAAEW 239
            +++   ++NK + +F++E    +E  I +  L+      D+     ++  L    D    
Sbjct: 2184 KEEQHESINKFEMDFIDEVEKQKELLIKIQHLQQDC---DVPSRELRDLKLNQNMD---- 2236

Query: 240  SLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKE---TKGFLDKLHNEITRT 296
             L +E +L        ++    +    Q+  +R  +   L+E   T+  ++KL N I + 
Sbjct: 2237 -LHIEEILKDFS---ESEFPSIKTEFQQVLSNRKEMTQFLEEWLNTRFDIEKLKNGIQKE 2292

Query: 297  LEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKV 356
             ++I     + NN++  ++ E    + + +   + ++Q           L  + E+ EK+
Sbjct: 2293 NDRICQVNNFFNNRIIAIMNESTEFEERSATISKEWEQD----------LKSLKEKNEKL 2342

Query: 357  KQEMEEKGSSMTDGA 371
             +  +   +S+  GA
Sbjct: 2343 FKNYQTLKTSLASGA 2357


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 55/240 (22%), Positives = 108/240 (45%), Gaps = 21/240 (8%)

Query: 170  VEELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDI 229
            +EELEEE  AE        K   ++  E  +  E   +   + +    L+    A   + 
Sbjct: 1116 IEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREA---EF 1172

Query: 230  LESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKL 289
            L+   D  E +L+ E ++  L+          + H D + +    I++ L+  K  L+K 
Sbjct: 1173 LKLRRDLEEATLQHEAMVAALR----------KKHADSVAELGEQIDN-LQRVKQKLEKE 1221

Query: 290  HNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEV 349
             +E    ++ +SS  + ++    NL +  R  + QLSEA+ + ++    ++E T   S +
Sbjct: 1222 KSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRL 1281

Query: 350  MEELEKVKQEMEEKGSSMTDGAPLVKIKQSLT----KLKQETVEMDIRIGIVEHTLLQSK 405
              E  ++ +++EEK S ++    L + KQ+ T    +LK++  E +     + H L  S+
Sbjct: 1282 QTEAGELSRQLEEKESIVSQ---LSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSR 1338



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 59/263 (22%), Positives = 111/263 (42%), Gaps = 36/263 (13%)

Query: 171  EELEEESVAEDDAELTLNKVDEE----------FVEEETDNEENFIDLN-----VLKAQT 215
            +E  E     DD ELTL KV++E            EE +  +E    L      + +A  
Sbjct: 946  DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQ 1005

Query: 216  YHLD--------MNETAKQEDILESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQ 267
              LD        +N   K +  LE   +  E SLE E+   +L+V +  + +     +  
Sbjct: 1006 QALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEK---KLRVDLERNKRKLEGDLKL 1062

Query: 268  MHQHRSGIESALKETKGFLDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSE 327
              +    +E+  ++    L K   E  +   K+   E+ +  Q +  ++E +A   +L E
Sbjct: 1063 AQESILDLENDKQQLDERLKKKDFEYCQLQSKVED-EQTLGLQFQKKIKELQARIEELEE 1121

Query: 328  AKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQS-LTKLKQE 386
              E  ++     TE+ R  S+   ELE++ + +EE G   +    L K +++   KL++ 
Sbjct: 1122 EIEA-ERATRAKTEKQR--SDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRR- 1177

Query: 387  TVEMDIRIGIVEHTLLQSKLKEK 409
                D+    ++H  + + L++K
Sbjct: 1178 ----DLEEATLQHEAMVAALRKK 1196



 Score = 32.3 bits (72), Expect = 0.85
 Identities = 49/251 (19%), Positives = 109/251 (43%), Gaps = 52/251 (20%)

Query: 171  EELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDIL 230
            E+ EEE   + + +  L+K + E  +  T  E + I       +T  L   E AK++ + 
Sbjct: 1346 EQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQ------RTEEL---EEAKKK-LA 1395

Query: 231  ESTTDAAEWSLEVERV------LPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKG 284
            +   D+ E   +VE V      L + K  ++ + +D  + V++ +   +           
Sbjct: 1396 QRLQDSEE---QVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAA---------- 1442

Query: 285  FLDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTR 344
             LDK      + L +  ++ +    +LE  ++E R+   +L + K  Y+           
Sbjct: 1443 -LDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYE----------- 1490

Query: 345  LLSEVMEELEKVKQE---MEEKGSSMTD-----GAPLVKIKQSLTKLKQETVEMDIRIGI 396
               E +++LE VK+E   +E++ + +T+     G  + ++++S  +++ E  ++ + +  
Sbjct: 1491 ---EALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEE 1547

Query: 397  VEHTLLQSKLK 407
             E  L   + K
Sbjct: 1548 AEAALEHEEAK 1558



 Score = 30.0 bits (66), Expect = 4.2
 Identities = 53/279 (18%), Positives = 108/279 (38%), Gaps = 15/279 (5%)

Query: 115  ISNILSELRSFGRTADFPPSKLKSGYGEHVCYVLDCFAEE-ALKYIGFTWKRPIYPVEEL 173
            + N+  EL     T      + K+    H   + D  AEE  +  +  T  +    VE+L
Sbjct: 976  VKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDL 1035

Query: 174  EEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQED----- 228
            E     E    + L +   +   +    +E+ +DL   K Q     ++E  K++D     
Sbjct: 1036 ESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQ-----LDERLKKKDFEYCQ 1090

Query: 229  ILESTTDAAEWSLEVERVLPQLKVTIRTDNKDW---RIHVDQMHQHRSGIESALKETKGF 285
            +     D     L+ ++ + +L+  I    ++    R    +  + RS     L+E    
Sbjct: 1091 LQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSER 1150

Query: 286  LDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRL 345
            L++     +  +E    RE        +L +     +A ++  ++++      + E+   
Sbjct: 1151 LEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDN 1210

Query: 346  LSEVMEELEKVKQEMEEKGSSMTDGAPLV-KIKQSLTKL 383
            L  V ++LEK K E + +   ++     V K K +L K+
Sbjct: 1211 LQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKI 1249


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 48/250 (19%), Positives = 110/250 (44%), Gaps = 14/250 (5%)

Query: 170  VEELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDI 229
            + +LEE    E+     L K   +   + TD  +   +L   +AQ   L M    K+E++
Sbjct: 1029 ITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAEL---QAQIAELKMQLAKKEEEL 1085

Query: 230  LESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKL 289
              +     E + +    L +++  + +   + +  ++     R+  E   ++    L+ L
Sbjct: 1086 QAALARVEEEAAQKNMALKKIR-ELESQISELQEDLESERASRNKAEKQKRDLGEELEAL 1144

Query: 290  HNEITRTLEKI-------SSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTER 342
              E+  TL+         S RE+ +N   + L +E +  +AQ+ E ++++ Q    + E+
Sbjct: 1145 KTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQ 1204

Query: 343  TRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQETVE---MDIRIGIVEH 399
                  V   LEK KQ +E +   + +   ++   +  ++ K++ VE    ++++   E 
Sbjct: 1205 LEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEG 1264

Query: 400  TLLQSKLKEK 409
              ++++L +K
Sbjct: 1265 ERVRTELADK 1274



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 50/230 (21%), Positives = 100/230 (43%), Gaps = 18/230 (7%)

Query: 173  LEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQ-----E 227
            +EEE+  ++ A   + +++ +  E + D E      N  KA+    D+ E  +      E
Sbjct: 1092 VEEEAAQKNMALKKIRELESQISELQEDLESERASRN--KAEKQKRDLGEELEALKTELE 1149

Query: 228  DILESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLD 287
            D L+ST    E   + E+ +  LK T+  + K     + +M Q  S     L E      
Sbjct: 1150 DTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTK 1209

Query: 288  KLHNEITRTLEKISSREKYINNQLENLVQ-------EYRAAQAQLSEAKERYQQGNGGVT 340
            ++   + +  + + +    + N+++ L+Q       + +  +AQL E + ++ +G    T
Sbjct: 1210 RVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRT 1269

Query: 341  ERTRLLSEVMEELEKVK---QEMEEKGSSMT-DGAPLVKIKQSLTKLKQE 386
            E    ++++  EL+ V     + + K S +T D + L    Q   +L QE
Sbjct: 1270 ELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQE 1319



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 55/275 (20%), Positives = 122/275 (44%), Gaps = 44/275 (16%)

Query: 173  LEEESVAEDDAELTLNKVDEEFVEEETDNEENF--IDLNVLKA-QTYHLDMNETAKQEDI 229
            LEEE+   +     + +   + VEE  +  E    +  N+ KA QT   +  E A +  +
Sbjct: 1176 LEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKV 1235

Query: 230  L-ESTTDAAEWSLEVERVLPQLKVT------IRTDNKD----WRIHVD------------ 266
            L +   D+     +VE  L +L+V       +RT+  D     ++ +D            
Sbjct: 1236 LLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSK 1295

Query: 267  --QMHQHRSGIESALKETKGFLDKLHNE---ITRTLEKISSREKYINNQLE-------NL 314
              ++ +  S +ES L++T+  L + + +   ++  L+++   +     QLE       NL
Sbjct: 1296 SSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNL 1355

Query: 315  VQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLV 374
             ++     AQ+++ K++ +   G +     +  ++ ++LE + Q  EEK ++        
Sbjct: 1356 EKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYD------ 1409

Query: 375  KIKQSLTKLKQETVEMDIRIGIVEHTLLQSKLKEK 409
            K++++ T+L+QE  ++ + +     +    + K+K
Sbjct: 1410 KLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQK 1444



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 49/205 (23%), Positives = 86/205 (41%), Gaps = 32/205 (15%)

Query: 170  VEELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDM----NETAK 225
            +EELE+E  A +DA+L L                  ++L  +KAQ +  D+     ++ +
Sbjct: 1541 LEELEDELQATEDAKLRLE-----------------VNLQAMKAQ-FERDLQGRDEQSEE 1582

Query: 226  QEDILESTTDAAEWSLEVERVLPQLKVTIR----TDNKDWRIHVDQMHQHRSGIESALKE 281
            ++  L       E  LE ER    + V  R     D KD   H+D  +++R      L++
Sbjct: 1583 KKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRK 1642

Query: 282  TKGFLDKLHNEITRT---LEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGG 338
             +  +     E+  T    E+I ++ K    +L+++  E    Q +L+ A+   +Q    
Sbjct: 1643 LQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQ-- 1700

Query: 339  VTERTRLLSEVMEELEKVKQEMEEK 363
              ER  L  E+     K    +EEK
Sbjct: 1701 -QERDELADEIANSSGKGALALEEK 1724



 Score = 35.8 bits (81), Expect = 0.077
 Identities = 43/220 (19%), Positives = 96/220 (43%), Gaps = 24/220 (10%)

Query: 174  EEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDILEST 233
            EE+  A D  E T  ++ +E        ++  +DL+  +    +L+  +    + + E  
Sbjct: 1402 EEKVAAYDKLEKTKTRLQQEL-------DDLLVDLDHQRQSACNLEKKQKKFDQLLAEEK 1454

Query: 234  TDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLHNEI 293
            T +A+++ E +R   + +     + K   +           +E A+ E K  L++L+ + 
Sbjct: 1455 TISAKYAEERDRAEAEAR---EKETKALSL--------ARALEEAM-EQKAELERLNKQF 1502

Query: 294  TRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGV--TERTRLLSEVME 351
               +E + S +  +   +  L +  RA + Q+ E K + ++    +  TE  +L  EV  
Sbjct: 1503 RTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNL 1562

Query: 352  ELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQETVEMD 391
            +  K + E + +G    D     K KQ + ++++   E++
Sbjct: 1563 QAMKAQFERDLQG---RDEQSEEKKKQLVRQVREMEAELE 1599



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 55/255 (21%), Positives = 105/255 (41%), Gaps = 50/255 (19%)

Query: 142  EHVCYVLDCFAEEA---LKYIGFTWKRPIYPVEELEEESVAEDDA--ELTLNKVDEEFVE 196
            E +C+ L+   EE     +++    K+    ++ELEE+   E+ A  +L L KV  E   
Sbjct: 914  EEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKL 973

Query: 197  EETDNEENFIDLNVLKAQTYHLDMNETAKQEDILESTTDAAEWSLEVERVLPQLKVTIRT 256
            ++ + E+      +L+ Q   L   +   ++ I E TT+  E   E  + L +LK     
Sbjct: 974  KKLEEEQI-----ILEDQNCKLAKEKKLLEDRIAEFTTNLTEEE-EKSKSLAKLK----- 1022

Query: 257  DNKDWRIHVDQMHQHRSGIESALKETKGFLDKLHNEITRTLEKISSREKYINNQLENLVQ 316
                        ++H + I   L+E     +K   E+ +T  K+      +++Q+  L  
Sbjct: 1023 ------------NKHEAMITD-LEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAEL-- 1067

Query: 317  EYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKI 376
                 QAQ++E K +              L++  EEL+     +EE+ +        ++ 
Sbjct: 1068 -----QAQIAELKMQ--------------LAKKEEELQAALARVEEEAAQKNMALKKIRE 1108

Query: 377  KQSLTKLKQETVEMD 391
             +S     QE +E +
Sbjct: 1109 LESQISELQEDLESE 1123


>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
          Length = 1417

 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 52/266 (19%), Positives = 124/266 (46%), Gaps = 33/266 (12%)

Query: 173  LEEESVAEDDAELTLNKVDEEFVEEETD----NEENFIDLNVLKAQTYHLDMNETAKQED 228
            L++E++   + E T  K++++  + E +     E +   L  ++ +          K++ 
Sbjct: 918  LQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQK 977

Query: 229  ILESTTDAAEWSLEVERVLPQLK------VTIRTDNKDWRIHVDQMH----QHRSGIE-- 276
            ++E T  A +  +E+++   +L       + ++ D ++  +H+ Q+     Q ++ +E  
Sbjct: 978  VIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKK 1037

Query: 277  -SALKETKGFLDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQG 335
             +A+KE +        E+T  L+K     + +  +L+N   E ++   QL E ++  Q+ 
Sbjct: 1038 TNAVKELEKLQHSTETELTEALQK----REVLETELQNAHGELKSTLRQLQELRDVLQKA 1093

Query: 336  NGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVK-----IKQSLTK-------L 383
               + E+   + ++  EL + K E+E+K   + +    +K     +KQ   +       +
Sbjct: 1094 QLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTI 1153

Query: 384  KQETVEMDIRIGIVEHTLLQSKLKEK 409
            ++   EM+ +I  +E TL +S+L+ K
Sbjct: 1154 REHRGEMEQKIIKLEGTLEKSELELK 1179



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 49/217 (22%), Positives = 95/217 (43%), Gaps = 32/217 (14%)

Query: 172  ELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDILE 231
            ELE+++ A  + E   +  + E  E     E    +L     Q  H ++  T +Q   L 
Sbjct: 1033 ELEKKTNAVKELEKLQHSTETELTEALQKREVLETEL-----QNAHGELKSTLRQLQELR 1087

Query: 232  STTDAAEWSLEVERV--------LPQLKVTIRTDNKDWRIHVDQMHQHRSG--------- 274
                 A+ SLE +          L + K+ I  D K   + +DQ  + R+          
Sbjct: 1088 DVLQKAQLSLEEKYTTIKDLTAELRECKMEIE-DKKQELLEMDQALKERNWELKQRAAQV 1146

Query: 275  --IESALKETKGFLDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERY 332
              ++  ++E +G +++   ++  TLEK     K  N Q+E+L         +L  AKE+ 
Sbjct: 1147 THLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESL-------NDKLQNAKEQL 1199

Query: 333  QQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTD 369
            ++    + +  + +S++ +E+E+ +Q M+E  S M +
Sbjct: 1200 REKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKE 1236



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 49/249 (19%), Positives = 106/249 (42%), Gaps = 24/249 (9%)

Query: 182  DAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDILESTTDAAEWSL 241
            + ++ +    +E +E +   +E   +L    AQ  HLDM        I E   +  +  +
Sbjct: 1113 ECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMT-------IREHRGEMEQKII 1165

Query: 242  EVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGI---ESALKETKGFLDKLHNEITRTLE 298
            ++E  L + ++ ++  NK      D++   +  +   E  + + +  + +L  EI RT +
Sbjct: 1166 KLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQ 1225

Query: 299  KISS-------REKYINNQLENLV---QEYRAAQAQLSEAKERYQQGNGGVTERTRLLSE 348
            ++         +E+YI  Q +  +   QE R  + Q+  +     +      +  R +  
Sbjct: 1226 RMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIER 1285

Query: 349  VMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQETVEMDIRIGIVEHTLLQSKLKE 408
            +  ELE +KQ  +EK +    G  L + +   +K+++  +E  ++  I + +     LKE
Sbjct: 1286 LSSELEDMKQLSKEKDA---HGNHLAE-ELGASKVREAHLEARMQAEIKKLSAEVESLKE 1341

Query: 409  KSNMTRNMH 417
              +M    H
Sbjct: 1342 AYHMEMISH 1350



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 46/272 (16%), Positives = 118/272 (43%), Gaps = 41/272 (15%)

Query: 173 LEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDILES 232
           ++E  + +  A LT N++ +  +      E +   L+ L+ +   L  ++ A+       
Sbjct: 568 IKEAEIQKLHANLTANQLSQSLITCNDSQESS--KLSSLETEPVKLGGHQVAESVKDQNQ 625

Query: 233 TTDAAEWSLEVERVLPQLK------VTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFL 286
            T   ++  E +R++  ++      + I  +N D ++++         I+  L E     
Sbjct: 626 HTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNS 685

Query: 287 DKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGV------- 339
            KL +E+T+   ++ + EK    QLE  +  Y +  A+ +E ++   + N  +       
Sbjct: 686 SKLESEMTKKCSQLLTLEK----QLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNI 741

Query: 340 -TERTRLL--------------SEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLK 384
            TE  ++                E+ +++E+++ ++E+K     +       +++++ L+
Sbjct: 742 NTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQ------EKTMSMLQ 795

Query: 385 QETVEMDIRIGIVEHTLLQSKLK-EKSNMTRN 415
           Q+ +     +  ++  L +SK + +K NM ++
Sbjct: 796 QDIICKQHHLESLDRLLTESKGEMKKENMKKD 827



 Score = 30.0 bits (66), Expect = 4.2
 Identities = 34/192 (17%), Positives = 81/192 (42%), Gaps = 14/192 (7%)

Query: 191  DEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQED--ILESTTDAAEWSLEVERVLP 248
            ++EF+  + + E + +   + + Q    +M    K+++  I     +A +   E+     
Sbjct: 1201 EKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTRE 1260

Query: 249  QLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFL---DKLHNEITRTLEKISSREK 305
            Q++ +  T+  + R    Q  +    + S L++ K      D   N +   L     RE 
Sbjct: 1261 QVQNS-HTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREA 1319

Query: 306  YINNQLENLVQEYRAAQAQLSEA--------KERYQQGNGGVTERTRLLSEVMEELEKVK 357
            ++  +++  +++  A    L EA        +E + +       +   + ++ E+LEK K
Sbjct: 1320 HLEARMQAEIKKLSAEVESLKEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAK 1379

Query: 358  QEMEEKGSSMTD 369
             E+EE   ++++
Sbjct: 1380 LELEEAQDTVSN 1391


>gi|118498362 kinectin 1 isoform b [Homo sapiens]
          Length = 1306

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 41/181 (22%), Positives = 90/181 (49%), Gaps = 23/181 (12%)

Query: 242  EVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLHNEITRTLEKIS 301
            E E +L +L+ ++  +   W++ VD+ H+    ++S+   ++  L++L +E         
Sbjct: 1122 ETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSE--------- 1172

Query: 302  SREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEME 361
                  N  +ENL +E    + +L +A+    + +  VTE   L +++ E L K++ E  
Sbjct: 1173 ------NKDIENLRREREHLEMELEKAE---MERSTYVTEVRELKAQLNETLTKLRTEQN 1223

Query: 362  EKGSSMTDGAPLVKIKQSLTKLKQETVEMDIRIGIVEHTLL--QSKLKEKSNMTRNMHAT 419
            E+     D   L K +QSL  ++ + V+      ++E++ +  +++  EK  M+ +++ T
Sbjct: 1224 ERQKVAGD---LHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSLNQT 1280

Query: 420  V 420
            V
Sbjct: 1281 V 1281



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 48/220 (21%), Positives = 102/220 (46%), Gaps = 27/220 (12%)

Query: 170  VEELEEESVAEDDAELTLNKVDEEFVEEE---TDNEENFIDLNVL-KAQTYHLDMNETAK 225
            VEEL++  + E D ++   K  EE +E E     N+E  + L++  K Q     +    +
Sbjct: 796  VEELKKV-IHEKDGKI---KSVEELLEAELLKVANKEKTVQLSITSKVQELQNLLKGKEE 851

Query: 226  QEDILESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHR---SGIESALKET 282
            Q + +++  +  E  L       Q    ++ +N+  + HV ++ QH    +   S  +E 
Sbjct: 852  QMNTMKAVLEEKEKDLANTGKWLQ---DLQEENESLKAHVQEVAQHNLKEASSASQFEEL 908

Query: 283  KGFLDKLHNEITRTLEKISSREKYINNQ---LENLVQEYRAAQAQLSEAKER-YQQGNGG 338
            +  L +  NE+ R    +  RE  ++++   L+++  E +  ++Q+ + K++ YQQ +  
Sbjct: 909  EIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSF 968

Query: 339  ---------VTERTRLLSEVMEELEKVKQEMEEKGSSMTD 369
                     ++ER + +S +  EL+ +K  +E +     D
Sbjct: 969  PPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNND 1008



 Score = 34.3 bits (77), Expect = 0.22
 Identities = 20/78 (25%), Positives = 41/78 (52%), Gaps = 2/78 (2%)

Query: 286 LDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRL 345
           L+K+   +    +KI   E+ + +++ N ++E++    Q    K   Q+    V+E+   
Sbjct: 668 LEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPN- 726

Query: 346 LSEVMEELEKVKQEMEEK 363
             +V+E++EK  QE +EK
Sbjct: 727 -KDVVEQMEKCIQEKDEK 743



 Score = 33.9 bits (76), Expect = 0.29
 Identities = 47/277 (16%), Positives = 113/277 (40%), Gaps = 44/277 (15%)

Query: 168 YPVEELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLN----VLKAQTYHLD-MNE 222
           + +E++++    +DD    +  ++E+   E ++  E F  LN     LK++   L  +  
Sbjct: 666 HELEKMQQSVYVKDDK---IRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVS 722

Query: 223 TAKQEDILESTTDAAEWSLEVERVLPQLKVT--------------IRTDNKDWRIHVDQM 268
               +D++E      +   E  + + +L  T              IRT+N      V  +
Sbjct: 723 EQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDL 782

Query: 269 HQHRSG----------IESALKETKGFLDKLHNEITRTLEKISSREKYINNQLENLVQE- 317
              ++           ++  + E  G +  +   +   L K++++EK +   + + VQE 
Sbjct: 783 KAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQLSITSKVQEL 842

Query: 318 ---YRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLV 374
               +  + Q++  K   ++    +    + L ++ EE E +K  ++E            
Sbjct: 843 QNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQH-------- 894

Query: 375 KIKQSLTKLKQETVEMDIRIGIVEHTLLQSKLKEKSN 411
            +K++ +  + E +E+ ++    E   L++ LKE+ +
Sbjct: 895 NLKEASSASQFEELEIVLKEKENELKRLEAMLKERES 931



 Score = 33.1 bits (74), Expect = 0.50
 Identities = 46/238 (19%), Positives = 94/238 (39%), Gaps = 50/238 (21%)

Query: 174 EEESVAEDDAELTLNKVDEEFVEEETDNEENFIDL-NVLKAQTYHLDMNETAKQEDILES 232
           +E  +  D    T N+++ +   E     +++  L N L  +T  L   E  K+      
Sbjct: 424 QENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKN----- 478

Query: 233 TTDAAEWSLEVERVLPQLKVTIRTDNKDW-------RIHVDQMHQHRSGIESALKETKGF 285
                      E+   QLKV ++   + W       R    +    +  ++S     +  
Sbjct: 479 ----------AEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENE 528

Query: 286 LDKLHNEITRTL-----------------EKISSREKYINNQLENLVQEYRAAQAQLSEA 328
           +  LH+++T TL                 +K  ++E+ +  Q+++++++  A +AQ+   
Sbjct: 529 VQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQI--- 585

Query: 329 KERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQE 386
               QQ +  +  +T   S + EEL KV  E +++     D   L   +  LT  ++E
Sbjct: 586 ----QQFHSQIAAQTS-ASVLAEELHKVIAEKDKQIKQTEDS--LASERDRLTSKEEE 636



 Score = 28.9 bits (63), Expect = 9.4
 Identities = 41/216 (18%), Positives = 90/216 (41%), Gaps = 34/216 (15%)

Query: 170  VEELEEESVAEDDAELTLNKVDEEFVEE---------ETDNEENFIDLNVLKAQTYHLDM 220
            V+EL+     +++   T+  V EE  ++         +   E   +  +V +   ++L  
Sbjct: 839  VQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKE 898

Query: 221  NETAKQEDILESTTDAAEWSLE-VERVLP----------QLKVTIRTDNKDWRIHVDQMH 269
              +A Q + LE      E  L+ +E +L           QL   ++ +NK ++  ++Q+ 
Sbjct: 899  ASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLK 958

Query: 270  QHRSGIESALKETKGFLDKLHNEITRTLEKISSREKYIN---NQLENLVQEYRAAQAQLS 326
            Q      S+           H E+ +    IS REK I+   N+L++L       + + +
Sbjct: 959  QQNYQQASSFPP--------HEELLKV---ISEREKEISGLWNELDSLKDAVEHQRKKNN 1007

Query: 327  EAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEE 362
            + +E+  +    +    ++L + + +  K +Q+  E
Sbjct: 1008 DLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVE 1043


>gi|118498368 kinectin 1 isoform c [Homo sapiens]
          Length = 1300

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 41/181 (22%), Positives = 90/181 (49%), Gaps = 23/181 (12%)

Query: 242  EVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLHNEITRTLEKIS 301
            E E +L +L+ ++  +   W++ VD+ H+    ++S+   ++  L++L +E         
Sbjct: 1116 ETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSE--------- 1166

Query: 302  SREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEME 361
                  N  +ENL +E    + +L +A+    + +  VTE   L +++ E L K++ E  
Sbjct: 1167 ------NKDIENLRREREHLEMELEKAE---MERSTYVTEVRELKAQLNETLTKLRTEQN 1217

Query: 362  EKGSSMTDGAPLVKIKQSLTKLKQETVEMDIRIGIVEHTLL--QSKLKEKSNMTRNMHAT 419
            E+     D   L K +QSL  ++ + V+      ++E++ +  +++  EK  M+ +++ T
Sbjct: 1218 ERQKVAGD---LHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSLNQT 1274

Query: 420  V 420
            V
Sbjct: 1275 V 1275



 Score = 34.3 bits (77), Expect = 0.22
 Identities = 20/78 (25%), Positives = 41/78 (52%), Gaps = 2/78 (2%)

Query: 286 LDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRL 345
           L+K+   +    +KI   E+ + +++ N ++E++    Q    K   Q+    V+E+   
Sbjct: 668 LEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPN- 726

Query: 346 LSEVMEELEKVKQEMEEK 363
             +V+E++EK  QE +EK
Sbjct: 727 -KDVVEQMEKCIQEKDEK 743



 Score = 33.1 bits (74), Expect = 0.50
 Identities = 46/238 (19%), Positives = 94/238 (39%), Gaps = 50/238 (21%)

Query: 174 EEESVAEDDAELTLNKVDEEFVEEETDNEENFIDL-NVLKAQTYHLDMNETAKQEDILES 232
           +E  +  D    T N+++ +   E     +++  L N L  +T  L   E  K+      
Sbjct: 424 QENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKN----- 478

Query: 233 TTDAAEWSLEVERVLPQLKVTIRTDNKDW-------RIHVDQMHQHRSGIESALKETKGF 285
                      E+   QLKV ++   + W       R    +    +  ++S     +  
Sbjct: 479 ----------AEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENE 528

Query: 286 LDKLHNEITRTL-----------------EKISSREKYINNQLENLVQEYRAAQAQLSEA 328
           +  LH+++T TL                 +K  ++E+ +  Q+++++++  A +AQ+   
Sbjct: 529 VQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQI--- 585

Query: 329 KERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQE 386
               QQ +  +  +T   S + EEL KV  E +++     D   L   +  LT  ++E
Sbjct: 586 ----QQFHSQIAAQTS-ASVLAEELHKVIAEKDKQIKQTEDS--LASERDRLTSKEEE 636


>gi|156104908 myosin heavy chain 6 [Homo sapiens]
          Length = 1939

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 62/263 (23%), Positives = 115/263 (43%), Gaps = 36/263 (13%)

Query: 171  EELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLD--MNETAKQED 228
            +E  E     DD ELTL KV++E  +  T+N+     +  L  +   LD  + +  K++ 
Sbjct: 947  DECSELKKDIDDLELTLAKVEKE--KHATENK-----VKNLTEEMAGLDEIIAKLTKEKK 999

Query: 229  ILESTTDAAEWSLEVER----VLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKG 284
             L+     A   L+VE      L + KV +     D    ++Q  + R  +E A ++ +G
Sbjct: 1000 ALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEG 1059

Query: 285  FLD-------KLHNEITRTLEKISSREKYINNQLENLVQEYRAA----------QAQLSE 327
             L         L N+  +  EK+  +E  IN Q   +  E   A          QA++ E
Sbjct: 1060 DLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEE 1119

Query: 328  AKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQ-E 386
             +E  +       +  +L S++  ELE++ + +EE G     GA  V+I+ +  +  + +
Sbjct: 1120 LEEELEAERTARAKVEKLRSDLSRELEEISERLEEAG-----GATSVQIEMNKKREAEFQ 1174

Query: 387  TVEMDIRIGIVEHTLLQSKLKEK 409
             +  D+    ++H    + L++K
Sbjct: 1175 KMRRDLEEATLQHEATAAALRKK 1197



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 36/131 (27%), Positives = 70/131 (53%), Gaps = 14/131 (10%)

Query: 293 ITRTLEKISSREKYINNQLENLVQE-------YRAAQAQLSEAKERYQQGNGGVTERTRL 345
           I  TLEK  +R K +  ++ +L+QE        +A Q  L++A+ER  Q    +  + +L
Sbjct: 861 IKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQ---LIKNKIQL 917

Query: 346 LSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQETVEMDIRIGIVEHTLLQSK 405
            ++V E  E+++ E EE  + +T  A   K++   ++LK++  ++++ +  VE     ++
Sbjct: 918 EAKVKEMNERLEDE-EEMNAELT--AKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 974

Query: 406 LKEKSNMTRNM 416
            K K N+T  M
Sbjct: 975 NKVK-NLTEEM 984



 Score = 38.1 bits (87), Expect = 0.015
 Identities = 82/376 (21%), Positives = 156/376 (41%), Gaps = 69/376 (18%)

Query: 91   AAWLINKAGRPFEQ-----PQEYDDPNATISNILSELRSFGRTADFPPSKLKSGYGEHVC 145
            AA  ++K  R F++      Q+Y++  + + +   E RS          KLK+ Y E + 
Sbjct: 1440 AAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL----FKLKNAYEESLE 1495

Query: 146  YVLDCFAEE----------ALKYIGFTWKRPIYPVEELEEESVAEDDAELTLNKVDEEFV 195
            + L+ F  E            + +G   K     V ELE+     +  +L L    EE  
Sbjct: 1496 H-LETFKRENKNLQEEISDLTEQLGEGGKN----VHELEKVRKQLEVEKLELQSALEE-A 1549

Query: 196  EEETDNEENFI-----DLNVLKAQTYHLDMNETAKQEDILES------TTDAAEWSLEVE 244
            E   ++EE  I     + N +KA+   ++     K E++ ++        D+ + SL+ E
Sbjct: 1550 EASLEHEEGKILRAQLEFNQIKAE---IERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAE 1606

Query: 245  ----RVLPQLKVTIRTDNKDWRI---HVDQM----HQHRSGIESALKETKGFLDKLHNEI 293
                  + ++K  +  D  +  I   H ++M     +    ++S LK+T+  LD      
Sbjct: 1607 TRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRAN 1666

Query: 294  TRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEEL 353
                E I+  E+  NN L+  ++E RA   Q   +++  +Q     +ER +LL      L
Sbjct: 1667 DDLKENIAIVERR-NNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL 1725

Query: 354  EKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQE--TVEMDIRIGIVEHTLLQSKLKEKSN 411
               K++ME         + L +++  + +  QE    E   +  I +  ++  +LK++ +
Sbjct: 1726 INQKKKME---------SDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQD 1776

Query: 412  -------MTRNMHATV 420
                   M +NM  T+
Sbjct: 1777 TSAHLERMKKNMEQTI 1792



 Score = 37.4 bits (85), Expect = 0.026
 Identities = 45/216 (20%), Positives = 92/216 (42%), Gaps = 21/216 (9%)

Query: 171  EELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDIL 230
            E+ EEE+ A+ + +  L+K + E  +  T  E + I       +T  L+     K    L
Sbjct: 1347 EQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQ------RTEELE-EAKKKLAQRL 1399

Query: 231  ESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLH 290
            +   +A E        L + K  ++ + +D  + V+     RS   +A       LDK  
Sbjct: 1400 QDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVE-----RSNAAAAA------LDKKQ 1448

Query: 291  NEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVM 350
                + L +   + +   ++LE+  +E R+   +L + K  Y++    +    R    + 
Sbjct: 1449 RNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQ 1508

Query: 351  EELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQE 386
            EE+  + +++ E G ++ +   L K+++ L   K E
Sbjct: 1509 EEISDLTEQLGEGGKNVHE---LEKVRKQLEVEKLE 1541



 Score = 33.1 bits (74), Expect = 0.50
 Identities = 45/235 (19%), Positives = 101/235 (42%), Gaps = 34/235 (14%)

Query: 170  VEELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDI 229
            V++LE     E    + L +   +   +    +E+ +DL   K Q   L+     K+ DI
Sbjct: 1033 VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQ---LEEKLKKKEFDI 1089

Query: 230  LESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKL 289
             +  +      +E E+VL    + ++   K+ +  ++++ +      +A    +  ++KL
Sbjct: 1090 NQQNS-----KIEDEQVLA---LQLQKKLKENQARIEELEEELEAERTA----RAKVEKL 1137

Query: 290  HNEITRTLEKISSREKYINNQLENLVQ-------EYRAAQAQLSEA-----------KER 331
             ++++R LE+IS R +         ++       E++  +  L EA           +++
Sbjct: 1138 RSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKK 1197

Query: 332  YQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDG-APLVKIKQSLTKLKQ 385
            +      + E+   L  V ++LEK K E + +   +T     ++K K +L K+ +
Sbjct: 1198 HADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSR 1252


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
            sapiens]
          Length = 1937

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 58/262 (22%), Positives = 116/262 (44%), Gaps = 34/262 (12%)

Query: 171  EELEEESVAEDDAELTLNKVDEE----------FVEEETDNEENFIDLNVLKA---QTYH 217
            +E  E     DD ELTL KV++E            EE    +E    L+  K    +T+ 
Sbjct: 948  DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQ 1007

Query: 218  LDMNETAKQEDI----------LESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQ 267
              +++   +ED           LE   D  E SLE E+   +L++ +    +     +  
Sbjct: 1008 QTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEK---KLRMDLERAKRKLEGDLKL 1064

Query: 268  MHQHRSGIESALKETKGFLDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSE 327
              +    +E+  ++    L+K   EI+  + KI   E+ +  QL+  ++E +A   +L E
Sbjct: 1065 AQESTMDMENDKQQLDEKLEKKEFEISNLISKIED-EQAVEIQLQKKIKELQARIEELGE 1123

Query: 328  AKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQET 387
              E  ++ +    E+ R  S++  ELE++ + +EE G + +    L K +++    + + 
Sbjct: 1124 EIEA-ERASRAKAEKQR--SDLSRELEEISERLEEAGGATSAQVELNKKREA----EFQK 1176

Query: 388  VEMDIRIGIVEHTLLQSKLKEK 409
            +  D+    ++H  + + L++K
Sbjct: 1177 LRRDLEEATLQHEAMVAALRKK 1198



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 40/203 (19%), Positives = 87/203 (42%), Gaps = 25/203 (12%)

Query: 165  RPIYPVEELEEESVAEDDAELTLNKVDE-EFVEEETDNEENFIDLNVLKA--QTYHLD-M 220
            R +  + E  EE+     A++ LNK  E EF +   D EE  +    + A  +  H D M
Sbjct: 1144 RELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSM 1203

Query: 221  NETAKQEDILESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALK 280
             E  +Q D L+                 ++K  +  +  + ++  D +  +   I  A  
Sbjct: 1204 AELGEQIDNLQ-----------------RVKQKLEKEKSELKMETDDLSSNAEAISKA-- 1244

Query: 281  ETKGFLDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVT 340
              KG L+K+   +   + ++ ++E+     + +L  +    Q +  E   +  + +  V+
Sbjct: 1245 --KGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVS 1302

Query: 341  ERTRLLSEVMEELEKVKQEMEEK 363
            + +R      +++E++K ++EE+
Sbjct: 1303 QLSRSKQASTQQIEELKHQLEEE 1325



 Score = 33.9 bits (76), Expect = 0.29
 Identities = 62/335 (18%), Positives = 126/335 (37%), Gaps = 42/335 (12%)

Query: 103  EQPQEYDDPNAT---ISNILSELRSFGRTADFPPSKLKSGYGEHVCYVLDCFAEEA-LKY 158
            E   E DD ++    IS     L    R+ +   S+LK+   E    + D  A+ A L+ 
Sbjct: 1226 ELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQT 1285

Query: 159  IGFTWKRPIYPVEELEEESVAEDDAELTLNKVDEEFVEEETDNEENFI--------DLNV 210
                + R +   + L  +      A     +  +  +EEET  +            D ++
Sbjct: 1286 EAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDL 1345

Query: 211  LKAQTYHLDMNETAKQEDILESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQ 270
            L+ Q       +   Q  + ++ ++ A+W  + E    Q    +    K     + +  +
Sbjct: 1346 LREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 1405

Query: 271  HRSGIESALKETKGFLDKLHNEIT--------------------RTLEKISS--REKYIN 308
            H   + +     +    +L NE+                     R  +K+ S  ++KY  
Sbjct: 1406 HVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEE 1465

Query: 309  NQ--LENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSS 366
             Q  LE   +E R+   +L + K  Y++    +    R    + +E+  + +++ E G  
Sbjct: 1466 TQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQ 1525

Query: 367  MTDGAPLVKIKQSLTKLKQETVEMDIRIGIVEHTL 401
            + +   L KIK+   +++QE  E+   +   E +L
Sbjct: 1526 IHE---LEKIKK---QVEQEKCEIQAALEEAEASL 1554


>gi|118498356 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 41/192 (21%), Positives = 95/192 (49%), Gaps = 17/192 (8%)

Query: 242  EVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLHNEITRTLEKIS 301
            E E +L +L+ ++  +   W++ VD+ H+    ++S+   ++  L++L +E  + +E + 
Sbjct: 1145 ETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSE-NKDIENLR 1203

Query: 302  SREKYINNQLE-------NLVQEYRAAQAQLSEAKER----YQQGNGGVTERTRLLSEVM 350
               +++  +LE         V E R  +  L+E +++    Y +      E   L +++ 
Sbjct: 1204 REREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLN 1263

Query: 351  EELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQETVEMDIRIGIVEHTLL--QSKLKE 408
            E L K++ E  E+     D   L K +QSL  ++ + V+      ++E++ +  +++  E
Sbjct: 1264 ETLTKLRTEQNERQKVAGD---LHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSE 1320

Query: 409  KSNMTRNMHATV 420
            K  M+ +++ TV
Sbjct: 1321 KETMSVSLNQTV 1332



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 40/218 (18%), Positives = 98/218 (44%), Gaps = 35/218 (16%)

Query: 170  VEELEEE--SVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQE 227
            V++L++E  ++ E+   + L K  +  +  +    +N +     +  T    + E  K++
Sbjct: 831  VQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEE--KEK 888

Query: 228  DILESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHR---SGIESALKETKG 284
            D+     +  +W  +++            +N+  + HV ++ QH    +   S  +E + 
Sbjct: 889  DL----ANTGKWLQDLQE-----------ENESLKAHVQEVAQHNLKEASSASQFEELEI 933

Query: 285  FLDKLHNEITRTLEKISSREKYINNQ---LENLVQEYRAAQAQLSEAKER-YQQGNGG-- 338
             L +  NE+ R    +  RE  ++++   L+++  E +  ++Q+ + K++ YQQ +    
Sbjct: 934  VLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPP 993

Query: 339  -------VTERTRLLSEVMEELEKVKQEMEEKGSSMTD 369
                   ++ER + +S +  EL+ +K  +E +     D
Sbjct: 994  HEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNND 1031



 Score = 34.3 bits (77), Expect = 0.22
 Identities = 20/78 (25%), Positives = 41/78 (52%), Gaps = 2/78 (2%)

Query: 286 LDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRL 345
           L+K+   +    +KI   E+ + +++ N ++E++    Q    K   Q+    V+E+   
Sbjct: 668 LEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPN- 726

Query: 346 LSEVMEELEKVKQEMEEK 363
             +V+E++EK  QE +EK
Sbjct: 727 -KDVVEQMEKCIQEKDEK 743



 Score = 33.1 bits (74), Expect = 0.50
 Identities = 46/238 (19%), Positives = 94/238 (39%), Gaps = 50/238 (21%)

Query: 174 EEESVAEDDAELTLNKVDEEFVEEETDNEENFIDL-NVLKAQTYHLDMNETAKQEDILES 232
           +E  +  D    T N+++ +   E     +++  L N L  +T  L   E  K+      
Sbjct: 424 QENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKN----- 478

Query: 233 TTDAAEWSLEVERVLPQLKVTIRTDNKDW-------RIHVDQMHQHRSGIESALKETKGF 285
                      E+   QLKV ++   + W       R    +    +  ++S     +  
Sbjct: 479 ----------AEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENE 528

Query: 286 LDKLHNEITRTL-----------------EKISSREKYINNQLENLVQEYRAAQAQLSEA 328
           +  LH+++T TL                 +K  ++E+ +  Q+++++++  A +AQ+   
Sbjct: 529 VQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQI--- 585

Query: 329 KERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQE 386
               QQ +  +  +T   S + EEL KV  E +++     D   L   +  LT  ++E
Sbjct: 586 ----QQFHSQIAAQTS-ASVLAEELHKVIAEKDKQIKQTEDS--LASERDRLTSKEEE 636



 Score = 28.9 bits (63), Expect = 9.4
 Identities = 41/216 (18%), Positives = 90/216 (41%), Gaps = 34/216 (15%)

Query: 170  VEELEEESVAEDDAELTLNKVDEEFVEE---------ETDNEENFIDLNVLKAQTYHLDM 220
            V+EL+     +++   T+  V EE  ++         +   E   +  +V +   ++L  
Sbjct: 862  VQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKE 921

Query: 221  NETAKQEDILESTTDAAEWSLE-VERVLP----------QLKVTIRTDNKDWRIHVDQMH 269
              +A Q + LE      E  L+ +E +L           QL   ++ +NK ++  ++Q+ 
Sbjct: 922  ASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLK 981

Query: 270  QHRSGIESALKETKGFLDKLHNEITRTLEKISSREKYIN---NQLENLVQEYRAAQAQLS 326
            Q      S+           H E+ +    IS REK I+   N+L++L       + + +
Sbjct: 982  QQNYQQASSFPP--------HEELLKV---ISEREKEISGLWNELDSLKDAVEHQRKKNN 1030

Query: 327  EAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEE 362
            + +E+  +    +    ++L + + +  K +Q+  E
Sbjct: 1031 DLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVE 1066


>gi|33620775 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 41/192 (21%), Positives = 95/192 (49%), Gaps = 17/192 (8%)

Query: 242  EVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLHNEITRTLEKIS 301
            E E +L +L+ ++  +   W++ VD+ H+    ++S+   ++  L++L +E  + +E + 
Sbjct: 1145 ETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSE-NKDIENLR 1203

Query: 302  SREKYINNQLE-------NLVQEYRAAQAQLSEAKER----YQQGNGGVTERTRLLSEVM 350
               +++  +LE         V E R  +  L+E +++    Y +      E   L +++ 
Sbjct: 1204 REREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLN 1263

Query: 351  EELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQETVEMDIRIGIVEHTLL--QSKLKE 408
            E L K++ E  E+     D   L K +QSL  ++ + V+      ++E++ +  +++  E
Sbjct: 1264 ETLTKLRTEQNERQKVAGD---LHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSE 1320

Query: 409  KSNMTRNMHATV 420
            K  M+ +++ TV
Sbjct: 1321 KETMSVSLNQTV 1332



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 40/218 (18%), Positives = 98/218 (44%), Gaps = 35/218 (16%)

Query: 170  VEELEEE--SVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQE 227
            V++L++E  ++ E+   + L K  +  +  +    +N +     +  T    + E  K++
Sbjct: 831  VQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEE--KEK 888

Query: 228  DILESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHR---SGIESALKETKG 284
            D+     +  +W  +++            +N+  + HV ++ QH    +   S  +E + 
Sbjct: 889  DL----ANTGKWLQDLQE-----------ENESLKAHVQEVAQHNLKEASSASQFEELEI 933

Query: 285  FLDKLHNEITRTLEKISSREKYINNQ---LENLVQEYRAAQAQLSEAKER-YQQGNGG-- 338
             L +  NE+ R    +  RE  ++++   L+++  E +  ++Q+ + K++ YQQ +    
Sbjct: 934  VLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPP 993

Query: 339  -------VTERTRLLSEVMEELEKVKQEMEEKGSSMTD 369
                   ++ER + +S +  EL+ +K  +E +     D
Sbjct: 994  HEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNND 1031



 Score = 34.3 bits (77), Expect = 0.22
 Identities = 20/78 (25%), Positives = 41/78 (52%), Gaps = 2/78 (2%)

Query: 286 LDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRL 345
           L+K+   +    +KI   E+ + +++ N ++E++    Q    K   Q+    V+E+   
Sbjct: 668 LEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPN- 726

Query: 346 LSEVMEELEKVKQEMEEK 363
             +V+E++EK  QE +EK
Sbjct: 727 -KDVVEQMEKCIQEKDEK 743



 Score = 33.1 bits (74), Expect = 0.50
 Identities = 46/238 (19%), Positives = 94/238 (39%), Gaps = 50/238 (21%)

Query: 174 EEESVAEDDAELTLNKVDEEFVEEETDNEENFIDL-NVLKAQTYHLDMNETAKQEDILES 232
           +E  +  D    T N+++ +   E     +++  L N L  +T  L   E  K+      
Sbjct: 424 QENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKN----- 478

Query: 233 TTDAAEWSLEVERVLPQLKVTIRTDNKDW-------RIHVDQMHQHRSGIESALKETKGF 285
                      E+   QLKV ++   + W       R    +    +  ++S     +  
Sbjct: 479 ----------AEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENE 528

Query: 286 LDKLHNEITRTL-----------------EKISSREKYINNQLENLVQEYRAAQAQLSEA 328
           +  LH+++T TL                 +K  ++E+ +  Q+++++++  A +AQ+   
Sbjct: 529 VQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQI--- 585

Query: 329 KERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQE 386
               QQ +  +  +T   S + EEL KV  E +++     D   L   +  LT  ++E
Sbjct: 586 ----QQFHSQIAAQTS-ASVLAEELHKVIAEKDKQIKQTEDS--LASERDRLTSKEEE 636



 Score = 28.9 bits (63), Expect = 9.4
 Identities = 41/216 (18%), Positives = 90/216 (41%), Gaps = 34/216 (15%)

Query: 170  VEELEEESVAEDDAELTLNKVDEEFVEE---------ETDNEENFIDLNVLKAQTYHLDM 220
            V+EL+     +++   T+  V EE  ++         +   E   +  +V +   ++L  
Sbjct: 862  VQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKE 921

Query: 221  NETAKQEDILESTTDAAEWSLE-VERVLP----------QLKVTIRTDNKDWRIHVDQMH 269
              +A Q + LE      E  L+ +E +L           QL   ++ +NK ++  ++Q+ 
Sbjct: 922  ASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLK 981

Query: 270  QHRSGIESALKETKGFLDKLHNEITRTLEKISSREKYIN---NQLENLVQEYRAAQAQLS 326
            Q      S+           H E+ +    IS REK I+   N+L++L       + + +
Sbjct: 982  QQNYQQASSFPP--------HEELLKV---ISEREKEISGLWNELDSLKDAVEHQRKKNN 1030

Query: 327  EAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEE 362
            + +E+  +    +    ++L + + +  K +Q+  E
Sbjct: 1031 DLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVE 1066


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 50/258 (19%), Positives = 110/258 (42%), Gaps = 18/258 (6%)

Query: 170  VEELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDI 229
            + ELE     E+ +   L K+  +   + +D  E   DL   +AQ   L M    K+E++
Sbjct: 1036 ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL---QAQIAELKMQLAKKEEEL 1092

Query: 230  LESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKL 289
              +     +   +    L +++  +     D +  +D     R+  E   ++    L+ L
Sbjct: 1093 QAALARLDDEIAQKNNALKKIR-ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEAL 1151

Query: 290  HNEITRTLEKISS-------REKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTER 342
              E+  TL+  ++       RE+ +    + L +E R+ +AQ+ E ++++ Q    +TE+
Sbjct: 1152 KTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQ 1211

Query: 343  TRLLSEVMEELEKVKQEMEEKGSSMTD-----GAPLVKIKQSLTKLKQETVEMDIRIGIV 397
                      L+K KQ +E++ + +       G    +++    KL+ +  E+  +    
Sbjct: 1212 LEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDG 1271

Query: 398  EHTLLQSKLKEKSNMTRN 415
            E    +++L +K +  +N
Sbjct: 1272 ERA--RAELNDKVHKLQN 1287



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 57/259 (22%), Positives = 104/259 (40%), Gaps = 38/259 (14%)

Query: 161  FTWKRPIYPVEELEEESVAEDD----AELTLNKVDEEFVEEETDNEENFIDLNVLKAQTY 216
            FT  +P+  V   EEE  A++D     +    K + E  E E  + +   + N+L+ Q  
Sbjct: 838  FTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQL- 896

Query: 217  HLDMNETAKQEDILESTTDAAEWSLEVERVLPQLKVTIRTDN---KDWRIHVDQMHQHRS 273
                 ET    +  E     A    E+E +L +++  +  +    +  +    +M Q   
Sbjct: 897  ---QAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 953

Query: 274  GIESALKETKGFLDKLHNEITRTLEKISSREKYI------NNQLE--------------- 312
             +E  L+E +    KL  E      KI   E  I      NN+L                
Sbjct: 954  DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT 1013

Query: 313  NLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTD--- 369
            NL +E   A+  L++ K +++     +  R +   +  +ELEK+K+++E   S   +   
Sbjct: 1014 NLAEEEEKAK-NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIA 1072

Query: 370  --GAPLVKIKQSLTKLKQE 386
               A + ++K  L K ++E
Sbjct: 1073 DLQAQIAELKMQLAKKEEE 1091



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 52/266 (19%), Positives = 102/266 (38%), Gaps = 24/266 (9%)

Query: 173  LEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQ-----E 227
            L++E   +++A   + +++    + + D +      N  KA+    D+ E  +      E
Sbjct: 1099 LDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARN--KAEKQKRDLGEELEALKTELE 1156

Query: 228  DILESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQ-HRSGIESA------LK 280
            D L+ST    E   + E+ +  LK  +  + +     V +M Q H   +E         K
Sbjct: 1157 DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFK 1216

Query: 281  ETKGFLDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVT 340
              K  LDK    + +    ++   + +    + +  + +  +AQ+ E + +   G     
Sbjct: 1217 RAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 1276

Query: 341  ERTRLLSEVMEELEKVK---QEMEEKGSSMT-DGAPLVKIKQSLTKLKQETVEMDIRIGI 396
            E    + ++  E+E V     E E K   +  D A L    Q   +L QE     + +  
Sbjct: 1277 ELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVST 1336

Query: 397  ------VEHTLLQSKLKEKSNMTRNM 416
                   E   LQ +L E+    +N+
Sbjct: 1337 KLRQLEEERNSLQDQLDEEMEAKQNL 1362



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 57/307 (18%), Positives = 118/307 (38%), Gaps = 70/307 (22%)

Query: 170  VEELEEESVAEDDAELTL--------NKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMN 221
            +EELE+E  A +DA+L L         + + +    +  NEE    L   +   Y  ++ 
Sbjct: 1548 LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQ-RQLHEYETELE 1606

Query: 222  ETAKQEDILESTTDAAEWSLE------------VERVLPQLKVTIRTDNKDWRIHVDQMH 269
            +  KQ  +  +     E  L+             E  + QL+  ++   KD++  ++   
Sbjct: 1607 DERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR-KLQAQMKDFQRELEDAR 1665

Query: 270  QHRSGIESALKETKGFLDKLHNEITRTLEKISSRE---KYINNQLENLVQE--------- 317
              R  I +  KE +     L  ++ +  E +++ E   K  + + E L +E         
Sbjct: 1666 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 1725

Query: 318  --------YRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEEL--------------EK 355
                      A  AQL E  E  Q     +++R R  ++  E+L              E 
Sbjct: 1726 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 1785

Query: 356  VKQEMEEKGSSM------TDGAPLVKIKQSLTKLKQETVEMDIRIGIVEHTLLQSKLKEK 409
             +Q++E +   +       +GA   K K ++  L+ +  +++ ++        + + +EK
Sbjct: 1786 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQV--------EQEAREK 1837

Query: 410  SNMTRNM 416
               T+++
Sbjct: 1838 QAATKSL 1844



 Score = 37.7 bits (86), Expect = 0.020
 Identities = 49/253 (19%), Positives = 103/253 (40%), Gaps = 21/253 (8%)

Query: 170  VEELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDI 229
            VEEL E+      A+  L+K  +   +E  D       L   K +  H      A+ +++
Sbjct: 1205 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1264

Query: 230  LESTTDAAEWSLEVERVLPQLKVTIRTDN---KDWRIHVDQMHQHRSGIESALKETKGFL 286
                +D      E+   + +L+  + +      +      ++ +  + + S L++T+  L
Sbjct: 1265 QSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELL 1324

Query: 287  DKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQ----------AQLSEAKERYQQGN 336
             +   +      K+   E+  N+  + L +E  A Q           QLS++K++ Q   
Sbjct: 1325 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFA 1384

Query: 337  GGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQETVEMDIRIGI 396
              V           +E+E + Q+ EEK ++        K++++  +L+QE    D+ + +
Sbjct: 1385 STVEALEEGKKRFQKEIENLTQQYEEKAAAYD------KLEKTKNRLQQEL--DDLVVDL 1436

Query: 397  VEHTLLQSKLKEK 409
                 L S L++K
Sbjct: 1437 DNQRQLVSNLEKK 1449



 Score = 35.8 bits (81), Expect = 0.077
 Identities = 38/173 (21%), Positives = 71/173 (41%), Gaps = 26/173 (15%)

Query: 192  EEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDILESTTDAAEWSLEVERVLPQLK 251
            EE +EEE  N E   D      Q      NE A +    +    A +   ++ER      
Sbjct: 1742 EEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ---QLER------ 1792

Query: 252  VTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLHNEITRTLEKISSREKYI---- 307
                  NK+ R    ++H+    ++S  K T   L+    ++   +E+  +REK      
Sbjct: 1793 -----QNKELR---SKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQ-EAREKQAATKS 1843

Query: 308  ----NNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKV 356
                + +L+ ++ +    +    + KE+ ++GN  V +  R L E  EE +++
Sbjct: 1844 LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRI 1896



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 44/258 (17%), Positives = 104/258 (40%), Gaps = 37/258 (14%)

Query: 171  EELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDIL 230
            +  E E+  ++   L+L +  EE +E + + E       +LKA+            ED++
Sbjct: 1472 DRAEAEAREKETKALSLARALEEALEAKEELERTN---KMLKAE-----------MEDLV 1517

Query: 231  ESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLH 290
             S  D  +   E+E+     K  + T  ++ +  ++++       E A    +  +  L 
Sbjct: 1518 SSKDDVGKNVHELEKS----KRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALK 1573

Query: 291  NEITRTLEKISSREKYINNQLENLVQEYRA------AQAQLSEAKERYQQGN-------- 336
             +  R L+    + +    QL+  + EY         Q  L+ A ++  +G+        
Sbjct: 1574 GQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQA 1633

Query: 337  ----GGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTK-LKQETVEMD 391
                 G  E  + L ++  +++  ++E+E+  +S  +     K  +   K L+ + +++ 
Sbjct: 1634 DSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQ 1693

Query: 392  IRIGIVEHTLLQSKLKEK 409
              +   E    Q+ L+++
Sbjct: 1694 EDLAAAERARKQADLEKE 1711


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 50/258 (19%), Positives = 110/258 (42%), Gaps = 18/258 (6%)

Query: 170  VEELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDI 229
            + ELE     E+ +   L K+  +   + +D  E   DL   +AQ   L M    K+E++
Sbjct: 1043 ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL---QAQIAELKMQLAKKEEEL 1099

Query: 230  LESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKL 289
              +     +   +    L +++  +     D +  +D     R+  E   ++    L+ L
Sbjct: 1100 QAALARLDDEIAQKNNALKKIR-ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEAL 1158

Query: 290  HNEITRTLEKISS-------REKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTER 342
              E+  TL+  ++       RE+ +    + L +E R+ +AQ+ E ++++ Q    +TE+
Sbjct: 1159 KTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQ 1218

Query: 343  TRLLSEVMEELEKVKQEMEEKGSSMTD-----GAPLVKIKQSLTKLKQETVEMDIRIGIV 397
                      L+K KQ +E++ + +       G    +++    KL+ +  E+  +    
Sbjct: 1219 LEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDG 1278

Query: 398  EHTLLQSKLKEKSNMTRN 415
            E    +++L +K +  +N
Sbjct: 1279 ERA--RAELNDKVHKLQN 1294



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 57/259 (22%), Positives = 104/259 (40%), Gaps = 38/259 (14%)

Query: 161  FTWKRPIYPVEELEEESVAEDD----AELTLNKVDEEFVEEETDNEENFIDLNVLKAQTY 216
            FT  +P+  V   EEE  A++D     +    K + E  E E  + +   + N+L+ Q  
Sbjct: 845  FTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQL- 903

Query: 217  HLDMNETAKQEDILESTTDAAEWSLEVERVLPQLKVTIRTDN---KDWRIHVDQMHQHRS 273
                 ET    +  E     A    E+E +L +++  +  +    +  +    +M Q   
Sbjct: 904  ---QAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 960

Query: 274  GIESALKETKGFLDKLHNEITRTLEKISSREKYI------NNQLE--------------- 312
             +E  L+E +    KL  E      KI   E  I      NN+L                
Sbjct: 961  DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT 1020

Query: 313  NLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTD--- 369
            NL +E   A+  L++ K +++     +  R +   +  +ELEK+K+++E   S   +   
Sbjct: 1021 NLAEEEEKAK-NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIA 1079

Query: 370  --GAPLVKIKQSLTKLKQE 386
               A + ++K  L K ++E
Sbjct: 1080 DLQAQIAELKMQLAKKEEE 1098



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 52/266 (19%), Positives = 102/266 (38%), Gaps = 24/266 (9%)

Query: 173  LEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQ-----E 227
            L++E   +++A   + +++    + + D +      N  KA+    D+ E  +      E
Sbjct: 1106 LDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARN--KAEKQKRDLGEELEALKTELE 1163

Query: 228  DILESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQ-HRSGIESA------LK 280
            D L+ST    E   + E+ +  LK  +  + +     V +M Q H   +E         K
Sbjct: 1164 DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFK 1223

Query: 281  ETKGFLDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVT 340
              K  LDK    + +    ++   + +    + +  + +  +AQ+ E + +   G     
Sbjct: 1224 RAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 1283

Query: 341  ERTRLLSEVMEELEKVK---QEMEEKGSSMT-DGAPLVKIKQSLTKLKQETVEMDIRIGI 396
            E    + ++  E+E V     E E K   +  D A L    Q   +L QE     + +  
Sbjct: 1284 ELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVST 1343

Query: 397  ------VEHTLLQSKLKEKSNMTRNM 416
                   E   LQ +L E+    +N+
Sbjct: 1344 KLRQLEEERNSLQDQLDEEMEAKQNL 1369



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 57/307 (18%), Positives = 118/307 (38%), Gaps = 70/307 (22%)

Query: 170  VEELEEESVAEDDAELTL--------NKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMN 221
            +EELE+E  A +DA+L L         + + +    +  NEE    L   +   Y  ++ 
Sbjct: 1555 LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQ-RQLHEYETELE 1613

Query: 222  ETAKQEDILESTTDAAEWSLE------------VERVLPQLKVTIRTDNKDWRIHVDQMH 269
            +  KQ  +  +     E  L+             E  + QL+  ++   KD++  ++   
Sbjct: 1614 DERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR-KLQAQMKDFQRELEDAR 1672

Query: 270  QHRSGIESALKETKGFLDKLHNEITRTLEKISSRE---KYINNQLENLVQE--------- 317
              R  I +  KE +     L  ++ +  E +++ E   K  + + E L +E         
Sbjct: 1673 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 1732

Query: 318  --------YRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEEL--------------EK 355
                      A  AQL E  E  Q     +++R R  ++  E+L              E 
Sbjct: 1733 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 1792

Query: 356  VKQEMEEKGSSM------TDGAPLVKIKQSLTKLKQETVEMDIRIGIVEHTLLQSKLKEK 409
             +Q++E +   +       +GA   K K ++  L+ +  +++ ++        + + +EK
Sbjct: 1793 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQV--------EQEAREK 1844

Query: 410  SNMTRNM 416
               T+++
Sbjct: 1845 QAATKSL 1851



 Score = 37.7 bits (86), Expect = 0.020
 Identities = 49/253 (19%), Positives = 103/253 (40%), Gaps = 21/253 (8%)

Query: 170  VEELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDI 229
            VEEL E+      A+  L+K  +   +E  D       L   K +  H      A+ +++
Sbjct: 1212 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1271

Query: 230  LESTTDAAEWSLEVERVLPQLKVTIRTDN---KDWRIHVDQMHQHRSGIESALKETKGFL 286
                +D      E+   + +L+  + +      +      ++ +  + + S L++T+  L
Sbjct: 1272 QSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELL 1331

Query: 287  DKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQ----------AQLSEAKERYQQGN 336
             +   +      K+   E+  N+  + L +E  A Q           QLS++K++ Q   
Sbjct: 1332 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFA 1391

Query: 337  GGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQETVEMDIRIGI 396
              V           +E+E + Q+ EEK ++        K++++  +L+QE    D+ + +
Sbjct: 1392 STVEALEEGKKRFQKEIENLTQQYEEKAAAYD------KLEKTKNRLQQEL--DDLVVDL 1443

Query: 397  VEHTLLQSKLKEK 409
                 L S L++K
Sbjct: 1444 DNQRQLVSNLEKK 1456



 Score = 35.8 bits (81), Expect = 0.077
 Identities = 38/173 (21%), Positives = 71/173 (41%), Gaps = 26/173 (15%)

Query: 192  EEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDILESTTDAAEWSLEVERVLPQLK 251
            EE +EEE  N E   D      Q      NE A +    +    A +   ++ER      
Sbjct: 1749 EEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ---QLER------ 1799

Query: 252  VTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLHNEITRTLEKISSREKYI---- 307
                  NK+ R    ++H+    ++S  K T   L+    ++   +E+  +REK      
Sbjct: 1800 -----QNKELR---SKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQ-EAREKQAATKS 1850

Query: 308  ----NNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKV 356
                + +L+ ++ +    +    + KE+ ++GN  V +  R L E  EE +++
Sbjct: 1851 LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRI 1903



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 44/258 (17%), Positives = 104/258 (40%), Gaps = 37/258 (14%)

Query: 171  EELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDIL 230
            +  E E+  ++   L+L +  EE +E + + E       +LKA+            ED++
Sbjct: 1479 DRAEAEAREKETKALSLARALEEALEAKEELERTN---KMLKAE-----------MEDLV 1524

Query: 231  ESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLH 290
             S  D  +   E+E+     K  + T  ++ +  ++++       E A    +  +  L 
Sbjct: 1525 SSKDDVGKNVHELEKS----KRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALK 1580

Query: 291  NEITRTLEKISSREKYINNQLENLVQEYRA------AQAQLSEAKERYQQGN-------- 336
             +  R L+    + +    QL+  + EY         Q  L+ A ++  +G+        
Sbjct: 1581 GQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQA 1640

Query: 337  ----GGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTK-LKQETVEMD 391
                 G  E  + L ++  +++  ++E+E+  +S  +     K  +   K L+ + +++ 
Sbjct: 1641 DSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQ 1700

Query: 392  IRIGIVEHTLLQSKLKEK 409
              +   E    Q+ L+++
Sbjct: 1701 EDLAAAERARKQADLEKE 1718


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 50/258 (19%), Positives = 110/258 (42%), Gaps = 18/258 (6%)

Query: 170  VEELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDI 229
            + ELE     E+ +   L K+  +   + +D  E   DL   +AQ   L M    K+E++
Sbjct: 1043 ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL---QAQIAELKMQLAKKEEEL 1099

Query: 230  LESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKL 289
              +     +   +    L +++  +     D +  +D     R+  E   ++    L+ L
Sbjct: 1100 QAALARLDDEIAQKNNALKKIR-ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEAL 1158

Query: 290  HNEITRTLEKISS-------REKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTER 342
              E+  TL+  ++       RE+ +    + L +E R+ +AQ+ E ++++ Q    +TE+
Sbjct: 1159 KTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQ 1218

Query: 343  TRLLSEVMEELEKVKQEMEEKGSSMTD-----GAPLVKIKQSLTKLKQETVEMDIRIGIV 397
                      L+K KQ +E++ + +       G    +++    KL+ +  E+  +    
Sbjct: 1219 LEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDG 1278

Query: 398  EHTLLQSKLKEKSNMTRN 415
            E    +++L +K +  +N
Sbjct: 1279 ERA--RAELNDKVHKLQN 1294



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 57/259 (22%), Positives = 104/259 (40%), Gaps = 38/259 (14%)

Query: 161  FTWKRPIYPVEELEEESVAEDD----AELTLNKVDEEFVEEETDNEENFIDLNVLKAQTY 216
            FT  +P+  V   EEE  A++D     +    K + E  E E  + +   + N+L+ Q  
Sbjct: 845  FTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQL- 903

Query: 217  HLDMNETAKQEDILESTTDAAEWSLEVERVLPQLKVTIRTDN---KDWRIHVDQMHQHRS 273
                 ET    +  E     A    E+E +L +++  +  +    +  +    +M Q   
Sbjct: 904  ---QAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 960

Query: 274  GIESALKETKGFLDKLHNEITRTLEKISSREKYI------NNQLE--------------- 312
             +E  L+E +    KL  E      KI   E  I      NN+L                
Sbjct: 961  DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT 1020

Query: 313  NLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTD--- 369
            NL +E   A+  L++ K +++     +  R +   +  +ELEK+K+++E   S   +   
Sbjct: 1021 NLAEEEEKAK-NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIA 1079

Query: 370  --GAPLVKIKQSLTKLKQE 386
               A + ++K  L K ++E
Sbjct: 1080 DLQAQIAELKMQLAKKEEE 1098



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 52/266 (19%), Positives = 102/266 (38%), Gaps = 24/266 (9%)

Query: 173  LEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQ-----E 227
            L++E   +++A   + +++    + + D +      N  KA+    D+ E  +      E
Sbjct: 1106 LDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARN--KAEKQKRDLGEELEALKTELE 1163

Query: 228  DILESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQ-HRSGIESA------LK 280
            D L+ST    E   + E+ +  LK  +  + +     V +M Q H   +E         K
Sbjct: 1164 DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFK 1223

Query: 281  ETKGFLDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVT 340
              K  LDK    + +    ++   + +    + +  + +  +AQ+ E + +   G     
Sbjct: 1224 RAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 1283

Query: 341  ERTRLLSEVMEELEKVK---QEMEEKGSSMT-DGAPLVKIKQSLTKLKQETVEMDIRIGI 396
            E    + ++  E+E V     E E K   +  D A L    Q   +L QE     + +  
Sbjct: 1284 ELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVST 1343

Query: 397  ------VEHTLLQSKLKEKSNMTRNM 416
                   E   LQ +L E+    +N+
Sbjct: 1344 KLRQLEEERNSLQDQLDEEMEAKQNL 1369



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 57/307 (18%), Positives = 118/307 (38%), Gaps = 70/307 (22%)

Query: 170  VEELEEESVAEDDAELTL--------NKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMN 221
            +EELE+E  A +DA+L L         + + +    +  NEE    L   +   Y  ++ 
Sbjct: 1555 LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQ-RQLHEYETELE 1613

Query: 222  ETAKQEDILESTTDAAEWSLE------------VERVLPQLKVTIRTDNKDWRIHVDQMH 269
            +  KQ  +  +     E  L+             E  + QL+  ++   KD++  ++   
Sbjct: 1614 DERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR-KLQAQMKDFQRELEDAR 1672

Query: 270  QHRSGIESALKETKGFLDKLHNEITRTLEKISSRE---KYINNQLENLVQE--------- 317
              R  I +  KE +     L  ++ +  E +++ E   K  + + E L +E         
Sbjct: 1673 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 1732

Query: 318  --------YRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEEL--------------EK 355
                      A  AQL E  E  Q     +++R R  ++  E+L              E 
Sbjct: 1733 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 1792

Query: 356  VKQEMEEKGSSM------TDGAPLVKIKQSLTKLKQETVEMDIRIGIVEHTLLQSKLKEK 409
             +Q++E +   +       +GA   K K ++  L+ +  +++ ++        + + +EK
Sbjct: 1793 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQV--------EQEAREK 1844

Query: 410  SNMTRNM 416
               T+++
Sbjct: 1845 QAATKSL 1851



 Score = 37.7 bits (86), Expect = 0.020
 Identities = 49/253 (19%), Positives = 103/253 (40%), Gaps = 21/253 (8%)

Query: 170  VEELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDI 229
            VEEL E+      A+  L+K  +   +E  D       L   K +  H      A+ +++
Sbjct: 1212 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1271

Query: 230  LESTTDAAEWSLEVERVLPQLKVTIRTDN---KDWRIHVDQMHQHRSGIESALKETKGFL 286
                +D      E+   + +L+  + +      +      ++ +  + + S L++T+  L
Sbjct: 1272 QSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELL 1331

Query: 287  DKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQ----------AQLSEAKERYQQGN 336
             +   +      K+   E+  N+  + L +E  A Q           QLS++K++ Q   
Sbjct: 1332 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFA 1391

Query: 337  GGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQETVEMDIRIGI 396
              V           +E+E + Q+ EEK ++        K++++  +L+QE    D+ + +
Sbjct: 1392 STVEALEEGKKRFQKEIENLTQQYEEKAAAYD------KLEKTKNRLQQEL--DDLVVDL 1443

Query: 397  VEHTLLQSKLKEK 409
                 L S L++K
Sbjct: 1444 DNQRQLVSNLEKK 1456



 Score = 35.8 bits (81), Expect = 0.077
 Identities = 38/173 (21%), Positives = 71/173 (41%), Gaps = 26/173 (15%)

Query: 192  EEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDILESTTDAAEWSLEVERVLPQLK 251
            EE +EEE  N E   D      Q      NE A +    +    A +   ++ER      
Sbjct: 1749 EEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ---QLER------ 1799

Query: 252  VTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLHNEITRTLEKISSREKYI---- 307
                  NK+ R    ++H+    ++S  K T   L+    ++   +E+  +REK      
Sbjct: 1800 -----QNKELR---SKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQ-EAREKQAATKS 1850

Query: 308  ----NNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKV 356
                + +L+ ++ +    +    + KE+ ++GN  V +  R L E  EE +++
Sbjct: 1851 LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRI 1903



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 44/258 (17%), Positives = 104/258 (40%), Gaps = 37/258 (14%)

Query: 171  EELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDIL 230
            +  E E+  ++   L+L +  EE +E + + E       +LKA+            ED++
Sbjct: 1479 DRAEAEAREKETKALSLARALEEALEAKEELERTN---KMLKAE-----------MEDLV 1524

Query: 231  ESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLH 290
             S  D  +   E+E+     K  + T  ++ +  ++++       E A    +  +  L 
Sbjct: 1525 SSKDDVGKNVHELEKS----KRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALK 1580

Query: 291  NEITRTLEKISSREKYINNQLENLVQEYRA------AQAQLSEAKERYQQGN-------- 336
             +  R L+    + +    QL+  + EY         Q  L+ A ++  +G+        
Sbjct: 1581 GQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQA 1640

Query: 337  ----GGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTK-LKQETVEMD 391
                 G  E  + L ++  +++  ++E+E+  +S  +     K  +   K L+ + +++ 
Sbjct: 1641 DSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQ 1700

Query: 392  IRIGIVEHTLLQSKLKEK 409
              +   E    Q+ L+++
Sbjct: 1701 EDLAAAERARKQADLEKE 1718


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 50/258 (19%), Positives = 110/258 (42%), Gaps = 18/258 (6%)

Query: 170  VEELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDI 229
            + ELE     E+ +   L K+  +   + +D  E   DL   +AQ   L M    K+E++
Sbjct: 1036 ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL---QAQIAELKMQLAKKEEEL 1092

Query: 230  LESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKL 289
              +     +   +    L +++  +     D +  +D     R+  E   ++    L+ L
Sbjct: 1093 QAALARLDDEIAQKNNALKKIR-ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEAL 1151

Query: 290  HNEITRTLEKISS-------REKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTER 342
              E+  TL+  ++       RE+ +    + L +E R+ +AQ+ E ++++ Q    +TE+
Sbjct: 1152 KTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQ 1211

Query: 343  TRLLSEVMEELEKVKQEMEEKGSSMTD-----GAPLVKIKQSLTKLKQETVEMDIRIGIV 397
                      L+K KQ +E++ + +       G    +++    KL+ +  E+  +    
Sbjct: 1212 LEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDG 1271

Query: 398  EHTLLQSKLKEKSNMTRN 415
            E    +++L +K +  +N
Sbjct: 1272 ERA--RAELNDKVHKLQN 1287



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 57/259 (22%), Positives = 104/259 (40%), Gaps = 38/259 (14%)

Query: 161  FTWKRPIYPVEELEEESVAEDD----AELTLNKVDEEFVEEETDNEENFIDLNVLKAQTY 216
            FT  +P+  V   EEE  A++D     +    K + E  E E  + +   + N+L+ Q  
Sbjct: 838  FTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQL- 896

Query: 217  HLDMNETAKQEDILESTTDAAEWSLEVERVLPQLKVTIRTDN---KDWRIHVDQMHQHRS 273
                 ET    +  E     A    E+E +L +++  +  +    +  +    +M Q   
Sbjct: 897  ---QAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 953

Query: 274  GIESALKETKGFLDKLHNEITRTLEKISSREKYI------NNQLE--------------- 312
             +E  L+E +    KL  E      KI   E  I      NN+L                
Sbjct: 954  DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT 1013

Query: 313  NLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTD--- 369
            NL +E   A+  L++ K +++     +  R +   +  +ELEK+K+++E   S   +   
Sbjct: 1014 NLAEEEEKAK-NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIA 1072

Query: 370  --GAPLVKIKQSLTKLKQE 386
               A + ++K  L K ++E
Sbjct: 1073 DLQAQIAELKMQLAKKEEE 1091



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 52/266 (19%), Positives = 102/266 (38%), Gaps = 24/266 (9%)

Query: 173  LEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQ-----E 227
            L++E   +++A   + +++    + + D +      N  KA+    D+ E  +      E
Sbjct: 1099 LDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARN--KAEKQKRDLGEELEALKTELE 1156

Query: 228  DILESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQ-HRSGIESA------LK 280
            D L+ST    E   + E+ +  LK  +  + +     V +M Q H   +E         K
Sbjct: 1157 DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFK 1216

Query: 281  ETKGFLDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVT 340
              K  LDK    + +    ++   + +    + +  + +  +AQ+ E + +   G     
Sbjct: 1217 RAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 1276

Query: 341  ERTRLLSEVMEELEKVK---QEMEEKGSSMT-DGAPLVKIKQSLTKLKQETVEMDIRIGI 396
            E    + ++  E+E V     E E K   +  D A L    Q   +L QE     + +  
Sbjct: 1277 ELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVST 1336

Query: 397  ------VEHTLLQSKLKEKSNMTRNM 416
                   E   LQ +L E+    +N+
Sbjct: 1337 KLRQLEEERNSLQDQLDEEMEAKQNL 1362



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 57/307 (18%), Positives = 118/307 (38%), Gaps = 70/307 (22%)

Query: 170  VEELEEESVAEDDAELTL--------NKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMN 221
            +EELE+E  A +DA+L L         + + +    +  NEE    L   +   Y  ++ 
Sbjct: 1548 LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQ-RQLHEYETELE 1606

Query: 222  ETAKQEDILESTTDAAEWSLE------------VERVLPQLKVTIRTDNKDWRIHVDQMH 269
            +  KQ  +  +     E  L+             E  + QL+  ++   KD++  ++   
Sbjct: 1607 DERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR-KLQAQMKDFQRELEDAR 1665

Query: 270  QHRSGIESALKETKGFLDKLHNEITRTLEKISSRE---KYINNQLENLVQE--------- 317
              R  I +  KE +     L  ++ +  E +++ E   K  + + E L +E         
Sbjct: 1666 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 1725

Query: 318  --------YRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEEL--------------EK 355
                      A  AQL E  E  Q     +++R R  ++  E+L              E 
Sbjct: 1726 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 1785

Query: 356  VKQEMEEKGSSM------TDGAPLVKIKQSLTKLKQETVEMDIRIGIVEHTLLQSKLKEK 409
             +Q++E +   +       +GA   K K ++  L+ +  +++ ++        + + +EK
Sbjct: 1786 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQV--------EQEAREK 1837

Query: 410  SNMTRNM 416
               T+++
Sbjct: 1838 QAATKSL 1844



 Score = 37.7 bits (86), Expect = 0.020
 Identities = 49/253 (19%), Positives = 103/253 (40%), Gaps = 21/253 (8%)

Query: 170  VEELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDI 229
            VEEL E+      A+  L+K  +   +E  D       L   K +  H      A+ +++
Sbjct: 1205 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1264

Query: 230  LESTTDAAEWSLEVERVLPQLKVTIRTDN---KDWRIHVDQMHQHRSGIESALKETKGFL 286
                +D      E+   + +L+  + +      +      ++ +  + + S L++T+  L
Sbjct: 1265 QSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELL 1324

Query: 287  DKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQ----------AQLSEAKERYQQGN 336
             +   +      K+   E+  N+  + L +E  A Q           QLS++K++ Q   
Sbjct: 1325 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFA 1384

Query: 337  GGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQETVEMDIRIGI 396
              V           +E+E + Q+ EEK ++        K++++  +L+QE    D+ + +
Sbjct: 1385 STVEALEEGKKRFQKEIENLTQQYEEKAAAYD------KLEKTKNRLQQEL--DDLVVDL 1436

Query: 397  VEHTLLQSKLKEK 409
                 L S L++K
Sbjct: 1437 DNQRQLVSNLEKK 1449



 Score = 35.8 bits (81), Expect = 0.077
 Identities = 38/173 (21%), Positives = 71/173 (41%), Gaps = 26/173 (15%)

Query: 192  EEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDILESTTDAAEWSLEVERVLPQLK 251
            EE +EEE  N E   D      Q      NE A +    +    A +   ++ER      
Sbjct: 1742 EEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ---QLER------ 1792

Query: 252  VTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLHNEITRTLEKISSREKYI---- 307
                  NK+ R    ++H+    ++S  K T   L+    ++   +E+  +REK      
Sbjct: 1793 -----QNKELR---SKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQ-EAREKQAATKS 1843

Query: 308  ----NNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKV 356
                + +L+ ++ +    +    + KE+ ++GN  V +  R L E  EE +++
Sbjct: 1844 LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRI 1896



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 44/258 (17%), Positives = 104/258 (40%), Gaps = 37/258 (14%)

Query: 171  EELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDIL 230
            +  E E+  ++   L+L +  EE +E + + E       +LKA+            ED++
Sbjct: 1472 DRAEAEAREKETKALSLARALEEALEAKEELERTN---KMLKAE-----------MEDLV 1517

Query: 231  ESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLH 290
             S  D  +   E+E+     K  + T  ++ +  ++++       E A    +  +  L 
Sbjct: 1518 SSKDDVGKNVHELEKS----KRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALK 1573

Query: 291  NEITRTLEKISSREKYINNQLENLVQEYRA------AQAQLSEAKERYQQGN-------- 336
             +  R L+    + +    QL+  + EY         Q  L+ A ++  +G+        
Sbjct: 1574 GQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQA 1633

Query: 337  ----GGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTK-LKQETVEMD 391
                 G  E  + L ++  +++  ++E+E+  +S  +     K  +   K L+ + +++ 
Sbjct: 1634 DSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQ 1693

Query: 392  IRIGIVEHTLLQSKLKEK 409
              +   E    Q+ L+++
Sbjct: 1694 EDLAAAERARKQADLEKE 1711


>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
          Length = 2003

 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 63/260 (24%), Positives = 118/260 (45%), Gaps = 23/260 (8%)

Query: 153  EEALKYIGFTWKRPIYPVEELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLK 212
            EE  + +    KR    ++ELE    AE+ A     K+  E V  E   ++   DL +L+
Sbjct: 960  EECSRQMQTEKKRLQQHIQELEAHLEAEEGAR---QKLQLEKVTTEAKMKKFEEDLLLLE 1016

Query: 213  AQTYHLDMNETAKQEDILESTTDAAEWS----------LEVERVLPQLKVTIRTDNKDWR 262
             Q   L       ++ + E ++ AAE            L+ E  +  ++  +R + K  R
Sbjct: 1017 DQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKG-R 1075

Query: 263  IHVDQMHQHRSGIESALKET----KGFLDKLHNEITRTLEKISS---REKYINNQLENLV 315
              ++++ +   G  S L+E     +   ++L  ++ R  E++ +   R +        L+
Sbjct: 1076 QELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLL 1135

Query: 316  QEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPL-V 374
            +  R AQA L+EA+E  +      T+  +   ++ EELE ++ E+E+   S      L  
Sbjct: 1136 KSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRS 1195

Query: 375  KIKQSLTKLKQETVEMDIRI 394
            K +Q +T+LK +T+E + RI
Sbjct: 1196 KREQEVTELK-KTLEEETRI 1214



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 49/248 (19%), Positives = 96/248 (38%), Gaps = 22/248 (8%)

Query: 152  AEEALKYIGFTWKRPIYPVEELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVL 211
            AEE    +G   +     +   E+E  A      +L +      E + D E   +     
Sbjct: 1103 AEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVART-- 1160

Query: 212  KAQTYHLDMNETAKQ-----EDILESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVD 266
            KA+    D+ E  +      ED L+ST    E   + E+ + +LK T+  + +     V 
Sbjct: 1161 KAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQ 1220

Query: 267  QMHQHRSGIESALKET-------KGFLDKLHNEITRTLEKISSREKYINNQLENLVQEYR 319
            ++ Q        L E        KG  +K    +   + ++ +    +    +   Q  R
Sbjct: 1221 ELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRR 1280

Query: 320  AAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDG-APLVKIKQ 378
              + QL E      QG  G  ER R  +E  E+L++ + E+E    ++ +  +  +++ +
Sbjct: 1281 RLELQLQEV-----QGRAGDGERAR--AEAAEKLQRAQAELENVSGALNEAESKTIRLSK 1333

Query: 379  SLTKLKQE 386
             L+  + +
Sbjct: 1334 ELSSTEAQ 1341



 Score = 33.1 bits (74), Expect = 0.50
 Identities = 51/242 (21%), Positives = 93/242 (38%), Gaps = 38/242 (15%)

Query: 170  VEELEEESVAEDDAELTL--------NKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMN 221
            V ELE+E  A +DA+L L         + + +    +   EE    L   + +   ++ +
Sbjct: 1573 VTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQL-AKQLRDAEVERD 1631

Query: 222  ETAKQEDILESTTDAAEWSLE------------VERVLPQLKVTIRTDNKDWRIHVDQMH 269
            E  KQ  +  +     E  LE             E  + QL+       + WR  V++  
Sbjct: 1632 EERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWR-EVEETR 1690

Query: 270  QHRSGIESALKETKGFLDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAK 329
              R  I S  +E++  L  L  E+ R  E++++ ++             R AQ    E  
Sbjct: 1691 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDR-----------ARRQAQQDRDEMA 1739

Query: 330  ERYQQGN---GGVTERTRLLSEVMEELEKVKQEMEEKGSSMTD--GAPLVKIKQSLTKLK 384
            +    GN     + E  R L   + +LE+  +E +     + D     L++++   T+L 
Sbjct: 1740 DEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELS 1799

Query: 385  QE 386
             E
Sbjct: 1800 AE 1801



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 40/197 (20%), Positives = 78/197 (39%), Gaps = 37/197 (18%)

Query: 171  EELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDIL 230
            E+LEEE+ A + A   L     +  E     EE          +   L+  E A++    
Sbjct: 1375 EQLEEEAAARERAGRELQTAQAQLSEWRRRQEE----------EAGALEAGEEARRRA-- 1422

Query: 231  ESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLH 290
                     + E E +  +L     T        VD++ + R  ++  L +    L++  
Sbjct: 1423 ---------AREAEALTQRLAEKTET--------VDRLERGRRRLQQELDDATMDLEQ-Q 1464

Query: 291  NEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVM 350
             ++  TLEK   +        + L+ E +AA  +  E +ER +        R   L+  +
Sbjct: 1465 RQLVSTLEKKQRK-------FDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRAL 1517

Query: 351  EELEKVKQEMEEKGSSM 367
            EE ++ ++E+E +  ++
Sbjct: 1518 EEEQEAREELERQNRAL 1534



 Score = 30.0 bits (66), Expect = 4.2
 Identities = 24/98 (24%), Positives = 45/98 (45%), Gaps = 8/98 (8%)

Query: 312  ENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGA 371
            E   +E + AQAQLSE + R ++  G +            E E + Q + EK  ++    
Sbjct: 1385 ERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVD--- 1441

Query: 372  PLVKIKQSLTKLKQETVEMDIRIGIVEHTLLQSKLKEK 409
               ++++   +L+QE    D  + + +   L S L++K
Sbjct: 1442 ---RLERGRRRLQQEL--DDATMDLEQQRQLVSTLEKK 1474


>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
          Length = 1995

 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 63/260 (24%), Positives = 118/260 (45%), Gaps = 23/260 (8%)

Query: 153  EEALKYIGFTWKRPIYPVEELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLK 212
            EE  + +    KR    ++ELE    AE+ A     K+  E V  E   ++   DL +L+
Sbjct: 952  EECSRQMQTEKKRLQQHIQELEAHLEAEEGAR---QKLQLEKVTTEAKMKKFEEDLLLLE 1008

Query: 213  AQTYHLDMNETAKQEDILESTTDAAEWS----------LEVERVLPQLKVTIRTDNKDWR 262
             Q   L       ++ + E ++ AAE            L+ E  +  ++  +R + K  R
Sbjct: 1009 DQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKG-R 1067

Query: 263  IHVDQMHQHRSGIESALKET----KGFLDKLHNEITRTLEKISS---REKYINNQLENLV 315
              ++++ +   G  S L+E     +   ++L  ++ R  E++ +   R +        L+
Sbjct: 1068 QELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLL 1127

Query: 316  QEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPL-V 374
            +  R AQA L+EA+E  +      T+  +   ++ EELE ++ E+E+   S      L  
Sbjct: 1128 KSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRS 1187

Query: 375  KIKQSLTKLKQETVEMDIRI 394
            K +Q +T+LK +T+E + RI
Sbjct: 1188 KREQEVTELK-KTLEEETRI 1206



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 49/248 (19%), Positives = 96/248 (38%), Gaps = 22/248 (8%)

Query: 152  AEEALKYIGFTWKRPIYPVEELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVL 211
            AEE    +G   +     +   E+E  A      +L +      E + D E   +     
Sbjct: 1095 AEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVART-- 1152

Query: 212  KAQTYHLDMNETAKQ-----EDILESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVD 266
            KA+    D+ E  +      ED L+ST    E   + E+ + +LK T+  + +     V 
Sbjct: 1153 KAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQ 1212

Query: 267  QMHQHRSGIESALKET-------KGFLDKLHNEITRTLEKISSREKYINNQLENLVQEYR 319
            ++ Q        L E        KG  +K    +   + ++ +    +    +   Q  R
Sbjct: 1213 ELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRR 1272

Query: 320  AAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDG-APLVKIKQ 378
              + QL E      QG  G  ER R  +E  E+L++ + E+E    ++ +  +  +++ +
Sbjct: 1273 RLELQLQEV-----QGRAGDGERAR--AEAAEKLQRAQAELENVSGALNEAESKTIRLSK 1325

Query: 379  SLTKLKQE 386
             L+  + +
Sbjct: 1326 ELSSTEAQ 1333



 Score = 33.1 bits (74), Expect = 0.50
 Identities = 51/242 (21%), Positives = 93/242 (38%), Gaps = 38/242 (15%)

Query: 170  VEELEEESVAEDDAELTL--------NKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMN 221
            V ELE+E  A +DA+L L         + + +    +   EE    L   + +   ++ +
Sbjct: 1565 VTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQL-AKQLRDAEVERD 1623

Query: 222  ETAKQEDILESTTDAAEWSLE------------VERVLPQLKVTIRTDNKDWRIHVDQMH 269
            E  KQ  +  +     E  LE             E  + QL+       + WR  V++  
Sbjct: 1624 EERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWR-EVEETR 1682

Query: 270  QHRSGIESALKETKGFLDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAK 329
              R  I S  +E++  L  L  E+ R  E++++ ++             R AQ    E  
Sbjct: 1683 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDR-----------ARRQAQQDRDEMA 1731

Query: 330  ERYQQGN---GGVTERTRLLSEVMEELEKVKQEMEEKGSSMTD--GAPLVKIKQSLTKLK 384
            +    GN     + E  R L   + +LE+  +E +     + D     L++++   T+L 
Sbjct: 1732 DEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELS 1791

Query: 385  QE 386
             E
Sbjct: 1792 AE 1793



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 40/197 (20%), Positives = 78/197 (39%), Gaps = 37/197 (18%)

Query: 171  EELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDIL 230
            E+LEEE+ A + A   L     +  E     EE          +   L+  E A++    
Sbjct: 1367 EQLEEEAAARERAGRELQTAQAQLSEWRRRQEE----------EAGALEAGEEARRRA-- 1414

Query: 231  ESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLH 290
                     + E E +  +L     T        VD++ + R  ++  L +    L++  
Sbjct: 1415 ---------AREAEALTQRLAEKTET--------VDRLERGRRRLQQELDDATMDLEQ-Q 1456

Query: 291  NEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVM 350
             ++  TLEK   +        + L+ E +AA  +  E +ER +        R   L+  +
Sbjct: 1457 RQLVSTLEKKQRK-------FDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRAL 1509

Query: 351  EELEKVKQEMEEKGSSM 367
            EE ++ ++E+E +  ++
Sbjct: 1510 EEEQEAREELERQNRAL 1526



 Score = 30.0 bits (66), Expect = 4.2
 Identities = 24/98 (24%), Positives = 45/98 (45%), Gaps = 8/98 (8%)

Query: 312  ENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGA 371
            E   +E + AQAQLSE + R ++  G +            E E + Q + EK  ++    
Sbjct: 1377 ERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVD--- 1433

Query: 372  PLVKIKQSLTKLKQETVEMDIRIGIVEHTLLQSKLKEK 409
               ++++   +L+QE    D  + + +   L S L++K
Sbjct: 1434 ---RLERGRRRLQQEL--DDATMDLEQQRQLVSTLEKK 1466


>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
          Length = 2036

 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 63/260 (24%), Positives = 118/260 (45%), Gaps = 23/260 (8%)

Query: 153  EEALKYIGFTWKRPIYPVEELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLK 212
            EE  + +    KR    ++ELE    AE+ A     K+  E V  E   ++   DL +L+
Sbjct: 993  EECSRQMQTEKKRLQQHIQELEAHLEAEEGAR---QKLQLEKVTTEAKMKKFEEDLLLLE 1049

Query: 213  AQTYHLDMNETAKQEDILESTTDAAEWS----------LEVERVLPQLKVTIRTDNKDWR 262
             Q   L       ++ + E ++ AAE            L+ E  +  ++  +R + K  R
Sbjct: 1050 DQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKG-R 1108

Query: 263  IHVDQMHQHRSGIESALKET----KGFLDKLHNEITRTLEKISS---REKYINNQLENLV 315
              ++++ +   G  S L+E     +   ++L  ++ R  E++ +   R +        L+
Sbjct: 1109 QELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLL 1168

Query: 316  QEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPL-V 374
            +  R AQA L+EA+E  +      T+  +   ++ EELE ++ E+E+   S      L  
Sbjct: 1169 KSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRS 1228

Query: 375  KIKQSLTKLKQETVEMDIRI 394
            K +Q +T+LK +T+E + RI
Sbjct: 1229 KREQEVTELK-KTLEEETRI 1247



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 49/248 (19%), Positives = 96/248 (38%), Gaps = 22/248 (8%)

Query: 152  AEEALKYIGFTWKRPIYPVEELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVL 211
            AEE    +G   +     +   E+E  A      +L +      E + D E   +     
Sbjct: 1136 AEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVART-- 1193

Query: 212  KAQTYHLDMNETAKQ-----EDILESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVD 266
            KA+    D+ E  +      ED L+ST    E   + E+ + +LK T+  + +     V 
Sbjct: 1194 KAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQ 1253

Query: 267  QMHQHRSGIESALKET-------KGFLDKLHNEITRTLEKISSREKYINNQLENLVQEYR 319
            ++ Q        L E        KG  +K    +   + ++ +    +    +   Q  R
Sbjct: 1254 ELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRR 1313

Query: 320  AAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDG-APLVKIKQ 378
              + QL E      QG  G  ER R  +E  E+L++ + E+E    ++ +  +  +++ +
Sbjct: 1314 RLELQLQEV-----QGRAGDGERAR--AEAAEKLQRAQAELENVSGALNEAESKTIRLSK 1366

Query: 379  SLTKLKQE 386
             L+  + +
Sbjct: 1367 ELSSTEAQ 1374



 Score = 33.1 bits (74), Expect = 0.50
 Identities = 51/242 (21%), Positives = 93/242 (38%), Gaps = 38/242 (15%)

Query: 170  VEELEEESVAEDDAELTL--------NKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMN 221
            V ELE+E  A +DA+L L         + + +    +   EE    L   + +   ++ +
Sbjct: 1606 VTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQL-AKQLRDAEVERD 1664

Query: 222  ETAKQEDILESTTDAAEWSLE------------VERVLPQLKVTIRTDNKDWRIHVDQMH 269
            E  KQ  +  +     E  LE             E  + QL+       + WR  V++  
Sbjct: 1665 EERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWR-EVEETR 1723

Query: 270  QHRSGIESALKETKGFLDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAK 329
              R  I S  +E++  L  L  E+ R  E++++ ++             R AQ    E  
Sbjct: 1724 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDR-----------ARRQAQQDRDEMA 1772

Query: 330  ERYQQGN---GGVTERTRLLSEVMEELEKVKQEMEEKGSSMTD--GAPLVKIKQSLTKLK 384
            +    GN     + E  R L   + +LE+  +E +     + D     L++++   T+L 
Sbjct: 1773 DEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELS 1832

Query: 385  QE 386
             E
Sbjct: 1833 AE 1834



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 40/197 (20%), Positives = 78/197 (39%), Gaps = 37/197 (18%)

Query: 171  EELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDIL 230
            E+LEEE+ A + A   L     +  E     EE          +   L+  E A++    
Sbjct: 1408 EQLEEEAAARERAGRELQTAQAQLSEWRRRQEE----------EAGALEAGEEARRRA-- 1455

Query: 231  ESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLH 290
                     + E E +  +L     T        VD++ + R  ++  L +    L++  
Sbjct: 1456 ---------AREAEALTQRLAEKTET--------VDRLERGRRRLQQELDDATMDLEQ-Q 1497

Query: 291  NEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVM 350
             ++  TLEK   +        + L+ E +AA  +  E +ER +        R   L+  +
Sbjct: 1498 RQLVSTLEKKQRK-------FDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRAL 1550

Query: 351  EELEKVKQEMEEKGSSM 367
            EE ++ ++E+E +  ++
Sbjct: 1551 EEEQEAREELERQNRAL 1567



 Score = 30.0 bits (66), Expect = 4.2
 Identities = 24/98 (24%), Positives = 45/98 (45%), Gaps = 8/98 (8%)

Query: 312  ENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGA 371
            E   +E + AQAQLSE + R ++  G +            E E + Q + EK  ++    
Sbjct: 1418 ERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVD--- 1474

Query: 372  PLVKIKQSLTKLKQETVEMDIRIGIVEHTLLQSKLKEK 409
               ++++   +L+QE    D  + + +   L S L++K
Sbjct: 1475 ---RLERGRRRLQQEL--DDATMDLEQQRQLVSTLEKK 1507


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 54/242 (22%), Positives = 104/242 (42%), Gaps = 17/242 (7%)

Query: 182 DAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDILESTTDAAEWSL 241
           + +L L K   E +E+E    +   +L    AQ        TA ++ + + T D +    
Sbjct: 317 ELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQ 376

Query: 242 EVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDK-------LHNEIT 294
             E     L+  I+   K+++  + +  +    ++    + K  L +       +HN + 
Sbjct: 377 NAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQ 436

Query: 295 RTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELE 354
             L+K++S    +  QLEN ++E++    +L  A++ +Q       E  R + E+ +E  
Sbjct: 437 AELDKLTS----VKQQLENNLEEFK---QKLCRAEQAFQASQIKENELRRSMEEMKKENN 489

Query: 355 KVKQEMEEKGSSMTD-GAPLVKIKQSLTKLKQETVEMDIRIGIVEHTLLQSKLKEKSNMT 413
            +K   E+K   +    A L  IKQ L + +    EM  +    + T+L+  L+EK N  
Sbjct: 490 LLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAK-NTSQETMLRD-LQEKINQQ 547

Query: 414 RN 415
            N
Sbjct: 548 EN 549



 Score = 37.0 bits (84), Expect = 0.034
 Identities = 47/259 (18%), Positives = 110/259 (42%), Gaps = 31/259 (11%)

Query: 182  DAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDILESTTDAAEWSL 241
            + EL + + ++E    E +N +   ++  LKA+   +  +    + D++   ++    + 
Sbjct: 2342 ERELEIARTNQEHAALEAENSKG--EVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTN 2399

Query: 242  EVERVLPQLKVTIRTDNKDWRIHVDQMHQHR-----------SGIESALKETKGFLDKLH 290
            E+++   ++   +   N  +   + +  Q +             +++ LKE    +  LH
Sbjct: 2400 ELQKEQERIS-ELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALH 2458

Query: 291  NEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVM 350
            N+     E   ++E+ +++Q+E L  E       L EAK  Y      V    + + +  
Sbjct: 2459 ND----QEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGK 2514

Query: 351  EELEKVKQEMEEKGSSMTDGAPLVK-----------IKQSLTKLKQETVEMDIRIGIVE- 398
            ++LEK  +E+    + + D   LV             K+   +L+  TVE++ +I +++ 
Sbjct: 2515 QKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQS 2574

Query: 399  -HTLLQSKLKEKSNMTRNM 416
             +  LQ  L+   +  +N+
Sbjct: 2575 KNASLQDTLEVLQSSYKNL 2593



 Score = 33.5 bits (75), Expect = 0.38
 Identities = 36/108 (33%), Positives = 49/108 (45%), Gaps = 19/108 (17%)

Query: 294 TRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGV----TERTRL---- 345
           TR L+KI   E     QL+ L +E +  Q QL   +   Q+    V    TE T L    
Sbjct: 14  TRALQKIQELE----GQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKREN 69

Query: 346 --LSEVMEELEKVKQ----EMEEKGSSMT-DGAPLVKIKQSLTKLKQE 386
             L E+ E LEK KQ    E++ K S +      L   K+ + KL+QE
Sbjct: 70  QRLMEICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQE 117



 Score = 33.1 bits (74), Expect = 0.50
 Identities = 60/313 (19%), Positives = 121/313 (38%), Gaps = 77/313 (24%)

Query: 162  TWKRPIYPVEE------LEEESVAED----DAELTLNKVDEEFVEEETDNEENFIDLNVL 211
            +WK     VE        E+ S+  +    +A+L + + ++  +E++ +N++  I     
Sbjct: 1892 SWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEE 1951

Query: 212  KAQTYHLDMNETAKQEDILESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQH 271
            +      + N+   + D +   T A          L QL   ++   ++   H  +    
Sbjct: 1952 ELSVVTSERNQLRGELDTMSKKTTA----------LDQLSEKMKEKTQELESHQSECLHC 2001

Query: 272  RSGIESALKETKGFLDKLHNEITRTL-------EKISSREK-----------------YI 307
                E+ +KE    L  L ++++  L       EK+ S EK                  +
Sbjct: 2002 IQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQL 2061

Query: 308  NNQLENLVQEYRAAQAQLSEA-----------------------------KERYQQGNGG 338
            N + E LV+E  + QA+LSE+                             +E +Q   G 
Sbjct: 2062 NKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGI 2121

Query: 339  VTERTRLLSEVMEEL---EKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQETVEMDIRIG 395
               R R+ ++  ++L   EK+K E E +  S+ D    ++ +  +++  QE V +D    
Sbjct: 2122 EKLRVRIEADEKKQLHIAEKLK-ERERENDSLKDKVENLERELQMSEENQELVILDAENS 2180

Query: 396  IVEHTLLQSKLKE 408
              E   L+++++E
Sbjct: 2181 KAEVETLKTQIEE 2193



 Score = 33.1 bits (74), Expect = 0.50
 Identities = 51/259 (19%), Positives = 105/259 (40%), Gaps = 42/259 (16%)

Query: 187  LNKVDEEFVEEETD-----NEENFIDLNVLKAQTYHLDMNETAKQEDILESTTDAAEWSL 241
            LNK  E  V+E        +E ++  LNV KA    L+     K E  L  ++   E   
Sbjct: 2061 LNKEKELLVKESESLQARLSESDYEKLNVSKA----LEAALVEKGEFALRLSSTQEEVH- 2115

Query: 242  EVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKE-------------------- 281
            ++ R + +L+V I  D K  ++H+ +  + R     +LK+                    
Sbjct: 2116 QLRRGIEKLRVRIEADEKK-QLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVI 2174

Query: 282  -----TKGFLDKLHNEI---TRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQ 333
                 +K  ++ L  +I    R+L+        + ++ ENL ++ +  Q QLSE  +   
Sbjct: 2175 LDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLS 2234

Query: 334  QGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQETVEMDIR 393
                 + E+ +   ++ EE +   + ++ +   + +    +   Q + K  +++++  I 
Sbjct: 2235 SFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIE 2294

Query: 394  IGIVEHTLLQSKLKEKSNM 412
                EH L  S  K ++ +
Sbjct: 2295 ---EEHQLRNSIEKLRARL 2310



 Score = 32.3 bits (72), Expect = 0.85
 Identities = 45/223 (20%), Positives = 89/223 (39%), Gaps = 30/223 (13%)

Query: 180  EDDAELTLNKVDEEFVEEETDNEENFIDLNVLK-----AQTYHLDMNETAKQEDI----L 230
            E + +L  +KV+ E  E +   + N +  + LK     ++T  L+  E +    +    +
Sbjct: 910  EKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREI 969

Query: 231  ESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLH 290
            E  T       E+   L Q K+ +   ++ +  ++D+  +  S +    K+ K  L    
Sbjct: 970  EELTQENGTLKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLIL---- 1025

Query: 291  NEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVM 350
                        R +   N  E+L Q+Y+AAQ + S+ +         + E T L     
Sbjct: 1026 ----------LQRCEETGNAYEDLSQKYKAAQEKNSKLECL-------LNECTSLCENRK 1068

Query: 351  EELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQETVEMDIR 393
             ELE++K+   ++           + +     L+ ETV+  +R
Sbjct: 1069 NELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALR 1111



 Score = 30.8 bits (68), Expect = 2.5
 Identities = 35/132 (26%), Positives = 58/132 (43%), Gaps = 13/132 (9%)

Query: 249  QLKVTIRTDNKDWRI-HVDQMHQHRSGIESALKETKGFLDKLHNEITRTLEKISSREKYI 307
            QL+V   T N++ R+ HV +    +  +ES L E K    KLH +  + + KI +     
Sbjct: 1773 QLRVK-ETSNENLRLLHVIEDRDRK--VESLLNEMKELDSKLHLQEVQLMTKIEA----- 1824

Query: 308  NNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSM 367
              +LE +V E +   + LSE  E +   +  + +R     E  E L    +   +K S  
Sbjct: 1825 CIELEKIVGELKKENSDLSEKLEYFSCDHQELLQRV----ETSEGLNSDLEMHADKSSRE 1880

Query: 368  TDGAPLVKIKQS 379
              G  + K+  S
Sbjct: 1881 DIGDNVAKVNDS 1892


>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 52/258 (20%), Positives = 114/258 (44%), Gaps = 26/258 (10%)

Query: 171  EELEEESVAEDDAELTLNKVDEEFVEEETDNE-ENFIDLNVLKAQTYHLDMNETAKQEDI 229
            +E  E     DD ELTL KV++E  +  T+N+ +N  +      +T      E    ++ 
Sbjct: 951  DECSELKKDIDDLELTLAKVEKE--KHATENKVKNLTEEMAGLDETIAKLTKEKKALQEA 1008

Query: 230  LESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLD-- 287
             + T D  +   +    L + K+ +     D    ++Q  + R  +E A ++ +G L   
Sbjct: 1009 HQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLA 1068

Query: 288  -----KLHNEITRTLEKISSREKYINNQLENLVQEYRAA-----------QAQLSEAKER 331
                  + NE  +  EK+  +E  I+N L++ +++ +A            QA++ E +E 
Sbjct: 1069 QESIMDIENEKQQLDEKLKKKEFEISN-LQSKIEDEQALGIQLQKKIKELQARIEELEEE 1127

Query: 332  YQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQETVEMD 391
             +       +  +  S++  ELE++ + +EE G + +    + K +++    + + +  D
Sbjct: 1128 IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREA----EFQKMRRD 1183

Query: 392  IRIGIVEHTLLQSKLKEK 409
            +    ++H    + L++K
Sbjct: 1184 LEEATLQHEATAATLRKK 1201



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 44/214 (20%), Positives = 93/214 (43%), Gaps = 26/214 (12%)

Query: 170  VEELEEESVAE-----------DDAELTLNKVDEEFVEEETDNEENFIDLNVLKA---QT 215
            +EELEEE  AE            D    L ++ E  +EE        I++N  +    Q 
Sbjct: 1121 IEELEEEIEAERASRAKAEKQRSDLSRELEEISER-LEEAGGATSAQIEMNKKREAEFQK 1179

Query: 216  YHLDMNETAKQEDILESTT------DAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMH 269
               D+ E   Q +   +T         AE   +++  L ++K  +  +  + ++ +D + 
Sbjct: 1180 MRRDLEEATLQHEATAATLRKKHADSVAELGEQIDN-LQRVKQKLEKEKSEMKMEIDDL- 1237

Query: 270  QHRSGIESALKETKGFLDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAK 329
               S +E+  K  KG L+K+   +   L ++ S+E+     + +L  +    Q +  E  
Sbjct: 1238 --ASNVETVSK-AKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFS 1294

Query: 330  ERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEK 363
             +  +    V++ +R      +++E++K+++EE+
Sbjct: 1295 RQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEE 1328



 Score = 37.4 bits (85), Expect = 0.026
 Identities = 55/260 (21%), Positives = 114/260 (43%), Gaps = 46/260 (17%)

Query: 171  EELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDIL 230
            E+ EEE  ++ + +  L+K + E  +  T  E + I       +T  L   E AK++  L
Sbjct: 1351 EQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQ------RTEEL---EEAKKK--L 1399

Query: 231  ESTTDAAEWSLEVERV----LPQLKVTIRTDNKDWRIHVDQ-------MHQHRSGIESAL 279
                 AAE  +E        L + K  ++ + +D  + V++       + + +   +  L
Sbjct: 1400 AQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKIL 1459

Query: 280  KETKGFLDKLHNEITRT----------LEKISSREKYINNQLENLVQEYRAAQAQLSEAK 329
             E K   ++ H E+  +          L KI +  +   +QLE L +E +  Q ++S+  
Sbjct: 1460 AEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLT 1519

Query: 330  ERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQETVE 389
            E+  +G   +            ELEK+K+++E++   +   A L + + SL   + + + 
Sbjct: 1520 EQIAEGGKRI-----------HELEKIKKQVEQEKCELQ--AALEEAEASLEHEEGKILR 1566

Query: 390  MDIRIGIVEHTLLQSKLKEK 409
            + + +  V+ + +  K+ EK
Sbjct: 1567 IQLELNQVK-SEVDRKIAEK 1585


>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 52/258 (20%), Positives = 114/258 (44%), Gaps = 26/258 (10%)

Query: 171  EELEEESVAEDDAELTLNKVDEEFVEEETDNE-ENFIDLNVLKAQTYHLDMNETAKQEDI 229
            +E  E     DD ELTL KV++E  +  T+N+ +N  +      +T      E    ++ 
Sbjct: 951  DECSELKKDIDDLELTLAKVEKE--KHATENKVKNLTEEMAGLDETIAKLTKEKKALQEA 1008

Query: 230  LESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLD-- 287
             + T D  +   +    L + K+ +     D    ++Q  + R  +E A ++ +G L   
Sbjct: 1009 HQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLA 1068

Query: 288  -----KLHNEITRTLEKISSREKYINNQLENLVQEYRAA-----------QAQLSEAKER 331
                  + NE  +  EK+  +E  I+N L++ +++ +A            QA++ E +E 
Sbjct: 1069 QESIMDIENEKQQLDEKLKKKEFEISN-LQSKIEDEQALGIQLQKKIKELQARIEELEEE 1127

Query: 332  YQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQETVEMD 391
             +       +  +  S++  ELE++ + +EE G + +    + K +++    + + +  D
Sbjct: 1128 IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREA----EFQKMRRD 1183

Query: 392  IRIGIVEHTLLQSKLKEK 409
            +    ++H    + L++K
Sbjct: 1184 LEEATLQHEATAATLRKK 1201



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 44/214 (20%), Positives = 93/214 (43%), Gaps = 26/214 (12%)

Query: 170  VEELEEESVAE-----------DDAELTLNKVDEEFVEEETDNEENFIDLNVLKA---QT 215
            +EELEEE  AE            D    L ++ E  +EE        I++N  +    Q 
Sbjct: 1121 IEELEEEIEAERASRAKAEKQRSDLSRELEEISER-LEEAGGATSAQIEMNKKREAEFQK 1179

Query: 216  YHLDMNETAKQEDILESTT------DAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMH 269
               D+ E   Q +   +T         AE   +++  L ++K  +  +  + ++ +D + 
Sbjct: 1180 MRRDLEEATLQHEATAATLRKKHADSVAELGEQIDN-LQRVKQKLEKEKSEMKMEIDDL- 1237

Query: 270  QHRSGIESALKETKGFLDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAK 329
               S +E+  K  KG L+K+   +   L ++ S+E+     + +L  +    Q +  E  
Sbjct: 1238 --ASNVETVSK-AKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFS 1294

Query: 330  ERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEK 363
             +  +    V++ +R      +++E++K+++EE+
Sbjct: 1295 RQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEE 1328



 Score = 37.4 bits (85), Expect = 0.026
 Identities = 55/260 (21%), Positives = 114/260 (43%), Gaps = 46/260 (17%)

Query: 171  EELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDIL 230
            E+ EEE  ++ + +  L+K + E  +  T  E + I       +T  L   E AK++  L
Sbjct: 1351 EQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQ------RTEEL---EEAKKK--L 1399

Query: 231  ESTTDAAEWSLEVERV----LPQLKVTIRTDNKDWRIHVDQ-------MHQHRSGIESAL 279
                 AAE  +E        L + K  ++ + +D  + V++       + + +   +  L
Sbjct: 1400 AQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKIL 1459

Query: 280  KETKGFLDKLHNEITRT----------LEKISSREKYINNQLENLVQEYRAAQAQLSEAK 329
             E K   ++ H E+  +          L KI +  +   +QLE L +E +  Q ++S+  
Sbjct: 1460 AEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLT 1519

Query: 330  ERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQETVE 389
            E+  +G   +            ELEK+K+++E++   +   A L + + SL   + + + 
Sbjct: 1520 EQIAEGGKRI-----------HELEKIKKQVEQEKCELQ--AALEEAEASLEHEEGKILR 1566

Query: 390  MDIRIGIVEHTLLQSKLKEK 409
            + + +  V+ + +  K+ EK
Sbjct: 1567 IQLELNQVK-SEVDRKIAEK 1585


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 43/213 (20%), Positives = 92/213 (43%), Gaps = 24/213 (11%)

Query: 170  VEELEEESVAEDDAELTLNKVDEEFVEEETDNEENF----------IDLNVLKA---QTY 216
            +EELEEE  AE      + K   +   E  +  E            I++N  +    Q  
Sbjct: 1119 IEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKM 1178

Query: 217  HLDMNETAKQEDILESTT------DAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQ 270
              D+ E   Q +   +T         AE   +++  L ++K  +  +  + ++ +D M  
Sbjct: 1179 RRDLEEATLQHEATAATLRKKQADSVAELGEQIDN-LQRVKQKLEKEKSELKMEIDDM-- 1235

Query: 271  HRSGIESALKETKGFLDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKE 330
              S IE AL ++K  +++    +     +I ++++     + +L  +    Q Q  E   
Sbjct: 1236 -ASNIE-ALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSH 1293

Query: 331  RYQQGNGGVTERTRLLSEVMEELEKVKQEMEEK 363
            R ++    +++ T+    + ++LE++K++MEE+
Sbjct: 1294 RVEEKESLISQLTKSKQALTQQLEELKRQMEEE 1326



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 57/283 (20%), Positives = 123/283 (43%), Gaps = 47/283 (16%)

Query: 171  EELEEESVA----EDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQ 226
            +ELEE+ V+    ++D +L +    E  ++ E   E       +L+A+   L   E  ++
Sbjct: 875  KELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKEL--TERLEE 932

Query: 227  EDILESTTDAAEWSLE-----VERVLPQLKVTIRTDNKDWRI---HVDQMHQHRSGIE-- 276
            E+ + S   A + +LE     ++R +  L++T+    K+       V  + +  + +E  
Sbjct: 933  EEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEEN 992

Query: 277  -SALKETKGFLDKLHNEITRTLE----------KISSREKYINNQLENLVQEYRAAQAQL 325
             S L + K  L + H +    L+          KI+++ +   + LE  +++ +  +A L
Sbjct: 993  ISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADL 1052

Query: 326  SEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEK------------GSSMTDGAPL 373
              AK + +          ++  E + +LE  KQ++EEK                 +    
Sbjct: 1053 ERAKRKLEGD-------LKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHS 1105

Query: 374  VKIKQSLTKLKQETVEMDIRIGIVEHTLLQSKLKEKSNMTRNM 416
            ++ ++ + +L+    E++  I   EHTL     K++S++ R +
Sbjct: 1106 LQFQKKIKELQARIEELEEEIE-AEHTLRAKIEKQRSDLAREL 1147



 Score = 33.1 bits (74), Expect = 0.50
 Identities = 43/237 (18%), Positives = 102/237 (43%), Gaps = 24/237 (10%)

Query: 171  EELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDIL 230
            E+ EEE  A+ + +  L+K + E  +  T  E + I     + +       + A++    
Sbjct: 1349 EQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQ----RTEELEEAKKKLAQRLQEA 1404

Query: 231  ESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLH 290
            E  T+ A         L + K  ++ + +D    +++ H   + ++   K+ + F DK+ 
Sbjct: 1405 EENTETANSKCAS---LEKTKQRLQGEVEDLMRDLERSHTACATLD---KKQRNF-DKVL 1457

Query: 291  NEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVM 350
             E  + L++  +       +LE   +E R+   +L + +  Y++    +    R    + 
Sbjct: 1458 AEWKQKLDESQA-------ELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQ 1510

Query: 351  EELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQETVEMDIRIGIVEHTLLQSKLK 407
            EE+  + +++ E G ++ +     K+      ++QE  ++ + +  VE +L   + K
Sbjct: 1511 EEISDLTEQIAETGKNLQEAEKTKKL------VEQEKSDLQVALEEVEGSLEHEESK 1561



 Score = 32.3 bits (72), Expect = 0.85
 Identities = 40/222 (18%), Positives = 86/222 (38%), Gaps = 11/222 (4%)

Query: 173  LEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDILES 232
            LE+E     D E    K++ +       ++E+ +DL   K Q       +  +   +   
Sbjct: 1042 LEQEKKLRADLERAKRKLEGDLKM----SQESIMDLENDKQQIEEKLKKKEFELSQLQAK 1097

Query: 233  TTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVD-----QMHQHRSGIESALKETKGFLD 287
              D    SL+ ++ + +L+   R +  +  I  +     ++ + RS +   L+E    L+
Sbjct: 1098 IDDEQVHSLQFQKKIKELQA--RIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLE 1155

Query: 288  KLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLS 347
            +     +  +E    RE        +L +     +A  +  +++       + E+   L 
Sbjct: 1156 EASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQ 1215

Query: 348  EVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQETVE 389
             V ++LEK K E++ +   M      +   +S  +    TVE
Sbjct: 1216 RVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVE 1257



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 41/220 (18%), Positives = 95/220 (43%), Gaps = 44/220 (20%)

Query: 170  VEELEEESVAEDDAELTLNKVDEEFVEE----ETDNEENFIDLNVLKAQTYHLDMNETAK 225
            +EELEE  VA +  E T    ++E ++     +  + +N   +N  K     +   +   
Sbjct: 1686 LEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEV 1745

Query: 226  QEDILES----------TTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGI 275
            +  I ES           TDAA  + E+++             +D   H+++M   +  +
Sbjct: 1746 ENSIQESRNAEEKAKKAITDAAMMAEELKK------------EQDTSAHLERM---KKNL 1790

Query: 276  ESALKETKGFLDKLHNEI----TRTLEKISSREKYINNQLENLVQEYRAAQA-------- 323
            E  +K+ +  LD+          + ++K+ +R + + N+L+  V++ R A+A        
Sbjct: 1791 EQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELD--VEQKRGAEALKGAHKYE 1848

Query: 324  -QLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEE 362
             ++ E   + ++ +  +     L+ ++  +++  K++ EE
Sbjct: 1849 RKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEE 1888


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 52/253 (20%), Positives = 118/253 (46%), Gaps = 36/253 (14%)

Query: 181  DDAELTLNKVDEE----------FVEEETDNEENFIDLNVLKA---QTYHLDMNETAKQE 227
            DD ELTL KV++E            EE    +E    L   K    + +   +++   +E
Sbjct: 955  DDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEE 1014

Query: 228  DILESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLD 287
            D + + T A    +++E+ +  L+ ++  + K   + +D + + +  +E  LK T+  + 
Sbjct: 1015 DKVNTLTKA---KVKLEQQVDDLEGSLEQEKK---VRMD-LERAKRKLEGDLKLTQESIM 1067

Query: 288  KLHNEITRTLEKISSRE---KYINNQLEN-------LVQEYRAAQAQLSEAKERYQQGNG 337
             L N+  +  E++  ++     +N ++E+       L ++ +  QA++ E +E  +    
Sbjct: 1068 DLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERT 1127

Query: 338  GVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQ-ETVEMDIRIGI 396
               +  +L S++  ELE++ + +EE G     GA  V+I+ +  +  + + +  D+    
Sbjct: 1128 ARAKVEKLRSDLSRELEEISERLEEAG-----GATSVQIEMNKKREAEFQKMRRDLEEAT 1182

Query: 397  VEHTLLQSKLKEK 409
            ++H    + L++K
Sbjct: 1183 LQHEATAAALRKK 1195



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 44/212 (20%), Positives = 96/212 (45%), Gaps = 22/212 (10%)

Query: 170  VEELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDI 229
            +EELEEE  AE  A   + K+  +   E  +  E   +     A +  ++MN+  ++ + 
Sbjct: 1115 IEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAG--GATSVQIEMNKK-REAEF 1171

Query: 230  LESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKL 289
             +   D  E +L+ E     L+        +    +D + + +  +E    E K  LD +
Sbjct: 1172 QKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDV 1231

Query: 290  HNEITRTLEKISSREKYINNQLENLVQEYRAAQAQ-------LSEAKERYQQGNGGVT-- 340
             + + + ++  ++ EK     LE+ + E+R+   +       L+  + + Q  NG ++  
Sbjct: 1232 TSNMEQIIKAKANLEKMCRT-LEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQ 1290

Query: 341  --ERTRLLSEVM-------EELEKVKQEMEEK 363
              E+  L+S++        ++LE +K+++EE+
Sbjct: 1291 LDEKEALISQLTRGKLTYTQQLEDLKRQLEEE 1322



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 40/152 (26%), Positives = 80/152 (52%), Gaps = 19/152 (12%)

Query: 275 IESALKETKGFLDKLHNEITR---TLEKISSREKYINNQLENLVQE-------YRAAQAQ 324
           ++SA +E +  +  +  E TR    LEK  +R K +  ++ +L+QE        +A Q  
Sbjct: 840 LKSAEREKE--MASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDN 897

Query: 325 LSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLK 384
           L++A+ER  Q    +  + +L ++V E  E+++ E EE  + +T  A   K++   ++LK
Sbjct: 898 LADAEERCDQ---LIKNKIQLEAKVKEMNERLEDE-EEMNAELT--AKKRKLEDECSELK 951

Query: 385 QETVEMDIRIGIVEHTLLQSKLKEKSNMTRNM 416
           ++  ++++ +  VE     ++ K K N+T  M
Sbjct: 952 RDIDDLELTLAKVEKEKHATENKVK-NLTEEM 982



 Score = 37.4 bits (85), Expect = 0.026
 Identities = 44/216 (20%), Positives = 91/216 (42%), Gaps = 21/216 (9%)

Query: 171  EELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDIL 230
            E+ EEE+ A+ + +  L+K + E  +  T  E + I       +T  L+     K    L
Sbjct: 1345 EQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQ------RTEELE-EAKKKLAQRL 1397

Query: 231  ESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLH 290
            +   +A E        L + K  ++ + +D  + V+     RS   +A       LDK  
Sbjct: 1398 QEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVE-----RSNAAAAA------LDKKQ 1446

Query: 291  NEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVM 350
                + L +   + +   ++LE+  +E R+   +L + K  Y++    +    R    + 
Sbjct: 1447 RNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQ 1506

Query: 351  EELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQE 386
            EE+  + +++   G ++ +   L K+++ L   K E
Sbjct: 1507 EEISDLTEQLGSSGKTIHE---LEKVRKQLEAEKME 1539



 Score = 33.1 bits (74), Expect = 0.50
 Identities = 44/233 (18%), Positives = 100/233 (42%), Gaps = 34/233 (14%)

Query: 170  VEELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDI 229
            V++LE     E    + L +   +   +    +E+ +DL   K Q     ++E  K++D 
Sbjct: 1031 VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQ-----LDERLKKKDF 1085

Query: 230  LESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKL 289
              +  +A    +E E+ L      ++   K+ +  ++++ +      +A    +  ++KL
Sbjct: 1086 ELNALNAR---IEDEQALGS---QLQKKLKELQARIEELEEELEAERTA----RAKVEKL 1135

Query: 290  HNEITRTLEKISSREKYINNQLENLVQ-------EYRAAQAQLSEA-----------KER 331
             ++++R LE+IS R +         ++       E++  +  L EA           +++
Sbjct: 1136 RSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKK 1195

Query: 332  YQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDG-APLVKIKQSLTKL 383
            +      + E+   L  V ++LEK K E + +   +T     ++K K +L K+
Sbjct: 1196 HADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKM 1248


>gi|16262452 cingulin [Homo sapiens]
          Length = 1203

 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 47/185 (25%), Positives = 93/185 (50%), Gaps = 8/185 (4%)

Query: 208 LNVLKAQTYHLD--MNETAKQEDILESTTDAAEWSLE-VERVLPQLKVTIRTDNKDWRIH 264
           L  L+A+   L+  +N + ++E  L +   A E  LE  +R L +L    +T N+     
Sbjct: 767 LQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTLNRALEEE 826

Query: 265 VDQMHQHRSGIESALKETKGFLDKLHNEITRTLEKISSREKYINNQLENLVQEYR-AAQA 323
             Q    R G ++ L+E K  LD+  + + + LEKI    K    QL+  +++Y+  A+ 
Sbjct: 827 GKQREVLRRG-KAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQLEDYKEKARR 885

Query: 324 QLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVK--IKQSLT 381
           ++++A+ + +       + +  LS + +E+++++Q + +   +  D A L K  + Q L 
Sbjct: 886 EVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQAL-QASQAERDTARLDKELLAQRLQ 944

Query: 382 KLKQE 386
            L+QE
Sbjct: 945 GLEQE 949



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 52/219 (23%), Positives = 90/219 (41%), Gaps = 40/219 (18%)

Query: 171 EELEEESVAEDDAELTLNKVDEEF--------VEEETDNEENFIDLNVLKA-QTYHLDMN 221
           EEL+E        E+     D E         VE +   E    +L + K  Q    D  
Sbjct: 639 EELKELQAERQSQEVAGRHRDRELEKQLAVLRVEADRGRELEEQNLQLQKTLQQLRQDCE 698

Query: 222 ETAKQEDILESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKE 281
           E +K + + E+             VL Q +  + T  ++ +   D+  +   G+E  LKE
Sbjct: 699 EASKAKMVAEAEAT----------VLGQRRAAVETTLRETQEENDEFRRRILGLEQQLKE 748

Query: 282 TKGFLD-------KLHNEITRTLEKISSREKYINNQLE---NLVQEYRAAQAQLSEAKER 331
           T+G +D       +L +++ R   +    E+ +N   E   +L    RA +A+L EA   
Sbjct: 749 TRGLVDGGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEA--- 805

Query: 332 YQQGNGGVTERTRLLSEVMEE-------LEKVKQEMEEK 363
            Q+G   + +  + L+  +EE       L + K E+EE+
Sbjct: 806 -QRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQ 843



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 37/147 (25%), Positives = 63/147 (42%), Gaps = 20/147 (13%)

Query: 283 KGFLDKLHNEITRTL-EKISSREKY------INNQLENLVQEYRAAQAQLSEAKERYQQG 335
           +G L +   E+ R L E++  R+K       +  QLE   +E    Q  L   K   QQ 
Sbjct: 361 QGELTRKVEELQRKLDEEVKKRQKLEPSQVGLERQLEEKTEECSRLQELLERRKGEAQQS 420

Query: 336 NGGVTERTRLL-----------SEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLK 384
           N  +    RLL           ++VME   K+K     + +       L++ ++ L ++ 
Sbjct: 421 NKELQNMKRLLDQGEDLRHGLETQVMELQNKLKHVQGPEPAKEVLLKDLLETRELLEEVL 480

Query: 385 Q--ETVEMDIRIGIVEHTLLQSKLKEK 409
           +  + VE  +R+   E T L+  LKE+
Sbjct: 481 EGKQRVEEQLRLRERELTALKGALKEE 507


>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
            sapiens]
          Length = 1939

 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 52/258 (20%), Positives = 114/258 (44%), Gaps = 26/258 (10%)

Query: 171  EELEEESVAEDDAELTLNKVDEEFVEEETDNE-ENFIDLNVLKAQTYHLDMNETAKQEDI 229
            +E  E     DD ELTL KV++E  +  T+N+ +N  +      +T      E    ++ 
Sbjct: 949  DECSELKKDIDDLELTLAKVEKE--KHATENKVKNLTEEMAGLDETIAKLTKEKKALQEA 1006

Query: 230  LESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKL 289
             + T D  +   +    L + K+ +     D    ++Q  + R  +E A ++ +G L KL
Sbjct: 1007 HQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDL-KL 1065

Query: 290  HNEITRTLE--------KISSRE---KYINNQLEN-------LVQEYRAAQAQLSEAKER 331
              E T  +E        K+  +E     + +++E+       L ++ +  QA++ E +E 
Sbjct: 1066 AQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEE 1125

Query: 332  YQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQETVEMD 391
             +       +  +  S++  ELE++ + +EE G + +    + K +++    + + +  D
Sbjct: 1126 IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREA----EFQKMRRD 1181

Query: 392  IRIGIVEHTLLQSKLKEK 409
            +    ++H    + L++K
Sbjct: 1182 LEEATLQHEATAATLRKK 1199



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 46/217 (21%), Positives = 99/217 (45%), Gaps = 17/217 (7%)

Query: 170  VEELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDI 229
            +EELEEE  AE  +     K   +   E  +  E   +     A +  ++MN+  ++ + 
Sbjct: 1119 IEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAG--GATSAQIEMNKK-REAEF 1175

Query: 230  LESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKL 289
             +   D  E +L+ E     L+          + H D + +    I++ L+  K  L+K 
Sbjct: 1176 QKMRRDLEEATLQHEATAATLR----------KKHADSVAELGEQIDN-LQRVKQKLEKE 1224

Query: 290  HNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEV 349
             +E+   ++ ++S  + ++    NL +  RA + QLSE K + ++    + + T   + +
Sbjct: 1225 KSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARL 1284

Query: 350  MEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQE 386
              E  +  ++++EK + ++    L + KQ+ T+  +E
Sbjct: 1285 QTESGEYSRQLDEKDTLVSQ---LSRGKQAFTQQIEE 1318



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 60/271 (22%), Positives = 119/271 (43%), Gaps = 52/271 (19%)

Query: 171  EELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDIL 230
            E+ EEE  A+ + +  ++K + E  +  T  E + I       +T  L   E AK++ + 
Sbjct: 1349 EQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQ------RTEEL---EEAKKK-LA 1398

Query: 231  ESTTDAAEWSLEVERV------LPQLKVTIRTDNKDWRIHVDQ-------MHQHRSGIES 277
            +   DA E    VE V      L + K  ++ + +D  I V++       + + +   + 
Sbjct: 1399 QRLQDAEE---HVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDK 1455

Query: 278  ALKETKGFLDKLHNEITRT----------LEKISSREKYINNQLENLVQEYRAAQAQLSE 327
             L E K   ++ H E+  +          L KI +  +   +QLE L +E +  Q ++S+
Sbjct: 1456 ILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISD 1515

Query: 328  AKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQET 387
              E+  +G   +            ELEK+K+++E++ S +   A L + + SL   + + 
Sbjct: 1516 LTEQIAEGGKRI-----------HELEKIKKQVEQEKSELQ--AALEEAEASLEHEEGKI 1562

Query: 388  VEMDIRIGIVEHTL---LQSKLKEKSNMTRN 415
            + + + +  V+  +   +  K +E   M RN
Sbjct: 1563 LRIQLELNQVKSEVDRKIAEKDEEIDQMKRN 1593


>gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1
           [Homo sapiens]
          Length = 1288

 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 57/263 (21%), Positives = 109/263 (41%), Gaps = 49/263 (18%)

Query: 172 ELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDILE 231
           E++ ++    D E  LNK+ + F+EE   N+E F  L++   Q      + T+K +  LE
Sbjct: 361 EMKAKNKDVKDTEKKLNKITK-FIEE---NKEKFTQLDLEDVQVREKLKHATSKAKK-LE 415

Query: 232 STTDAAEWSLEVERVLPQLKVTI---------------RTDNKDWRIHVDQMHQHRSGI- 275
                 +  +E  + +P     I                 + K  +  +D + Q   G+ 
Sbjct: 416 KQLQKDKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQ 475

Query: 276 ---ESALKETKGFLDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERY 332
              ES  KE  GF        ++++ +  S+     ++L+  +  +  A +QL++AKE  
Sbjct: 476 KEKESREKELMGF--------SKSVNEARSKMDVAQSELDIYLSRHNTAVSQLTKAKEAL 527

Query: 333 QQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQETVEMDI 392
              +  + ER   + ++  +L + +QE++EK             ++ L KL QE      
Sbjct: 528 IAASETLKERKAAIRDIEGKLPQTEQELKEK-------------EKELQKLTQEETNFKS 574

Query: 393 RIGIVEHTLLQSKLKEKSNMTRN 415
            +    H L Q   + KS++  N
Sbjct: 575 LV----HDLFQKVEEAKSSLAMN 593



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 39/203 (19%), Positives = 89/203 (43%), Gaps = 16/203 (7%)

Query: 210 VLKAQTYHLDMNETAKQEDILESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMH 269
           +L+ +   + M +   Q +  E   +  E  +   R+   +KV  R         V+ ++
Sbjct: 227 ILQGEVEQIAMMKPKGQTEHDEGMLEYLEDIIGCGRLNEPIKVLCR--------RVEILN 278

Query: 270 QHRSGIESALKETKGFLDKLHNEITRTLEKISSREKYI---NNQLENLVQEYRAAQAQLS 326
           +HR    + +K  +   D L  E    +E ++   +     N+  +  + E +   A++ 
Sbjct: 279 EHRGEKLNRVKMVEKEKDALEGEKNIAIEFLTLENEIFRKKNHVCQYYIYELQKRIAEME 338

Query: 327 EAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQE 386
             KE+  +    + E++ +LS  M+   K  ++ E+K + +T    + + K+  T+L  E
Sbjct: 339 TQKEKIHEDTKEINEKSNILSNEMKAKNKDVKDTEKKLNKITKF--IEENKEKFTQLDLE 396

Query: 387 TVEMDIRIGIVEHTLLQSKLKEK 409
            V++  ++   +H   ++K  EK
Sbjct: 397 DVQVREKL---KHATSKAKKLEK 416


>gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1
           [Homo sapiens]
          Length = 1288

 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 57/263 (21%), Positives = 109/263 (41%), Gaps = 49/263 (18%)

Query: 172 ELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDILE 231
           E++ ++    D E  LNK+ + F+EE   N+E F  L++   Q      + T+K +  LE
Sbjct: 361 EMKAKNKDVKDTEKKLNKITK-FIEE---NKEKFTQLDLEDVQVREKLKHATSKAKK-LE 415

Query: 232 STTDAAEWSLEVERVLPQLKVTI---------------RTDNKDWRIHVDQMHQHRSGI- 275
                 +  +E  + +P     I                 + K  +  +D + Q   G+ 
Sbjct: 416 KQLQKDKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQ 475

Query: 276 ---ESALKETKGFLDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERY 332
              ES  KE  GF        ++++ +  S+     ++L+  +  +  A +QL++AKE  
Sbjct: 476 KEKESREKELMGF--------SKSVNEARSKMDVAQSELDIYLSRHNTAVSQLTKAKEAL 527

Query: 333 QQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQETVEMDI 392
              +  + ER   + ++  +L + +QE++EK             ++ L KL QE      
Sbjct: 528 IAASETLKERKAAIRDIEGKLPQTEQELKEK-------------EKELQKLTQEETNFKS 574

Query: 393 RIGIVEHTLLQSKLKEKSNMTRN 415
            +    H L Q   + KS++  N
Sbjct: 575 LV----HDLFQKVEEAKSSLAMN 593



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 39/203 (19%), Positives = 89/203 (43%), Gaps = 16/203 (7%)

Query: 210 VLKAQTYHLDMNETAKQEDILESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMH 269
           +L+ +   + M +   Q +  E   +  E  +   R+   +KV  R         V+ ++
Sbjct: 227 ILQGEVEQIAMMKPKGQTEHDEGMLEYLEDIIGCGRLNEPIKVLCR--------RVEILN 278

Query: 270 QHRSGIESALKETKGFLDKLHNEITRTLEKISSREKYI---NNQLENLVQEYRAAQAQLS 326
           +HR    + +K  +   D L  E    +E ++   +     N+  +  + E +   A++ 
Sbjct: 279 EHRGEKLNRVKMVEKEKDALEGEKNIAIEFLTLENEIFRKKNHVCQYYIYELQKRIAEME 338

Query: 327 EAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQE 386
             KE+  +    + E++ +LS  M+   K  ++ E+K + +T    + + K+  T+L  E
Sbjct: 339 TQKEKIHEDTKEINEKSNILSNEMKAKNKDVKDTEKKLNKITKF--IEENKEKFTQLDLE 396

Query: 387 TVEMDIRIGIVEHTLLQSKLKEK 409
            V++  ++   +H   ++K  EK
Sbjct: 397 DVQVREKL---KHATSKAKKLEK 416


>gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]
          Length = 495

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 56/241 (23%), Positives = 118/241 (48%), Gaps = 18/241 (7%)

Query: 182 DAELTLNKVDEE--FVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDILESTTDAAEW 239
           DAE+    ++E    ++EE   E+     N  KAQ Y+LD+ +  ++++  +   +A E 
Sbjct: 155 DAEIAKTMMEEHKRIIKEENAAEDK---RNKAKAQ-YYLDLEKQLEEQE--KKKQEAYEQ 208

Query: 240 SLEVERVLPQLKVTI-RTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLHNEITRTLE 298
            L+ + ++ ++   I   D  + +  +++M+  R  IE   KE   +  K   E+     
Sbjct: 209 LLKEKLMIDEIVRKIYEEDQLEKQQKLEKMNAMRRYIEEFQKEQALWRKKKREEMEEENR 268

Query: 299 KISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQ 358
           KI    ++ N Q +   +E R A+ Q  E +E+  Q    +T++   +    E+LE+V+Q
Sbjct: 269 KII---EFANMQQQR--EEDRMAKVQ--ENEEKRLQLQNALTQKLEEMLRQREDLEQVRQ 321

Query: 359 EM-EEKGSSMTDGAPLVKIKQSLTKLKQETVEMDIRIGIVEHTLLQSKLKEKSNMTRNMH 417
           E+ +E+ + +       + ++ L K K+   + + ++ + E  +LQ+  +E+ N  + M 
Sbjct: 322 ELYQEEQAEIYKSKLKEEAEKKLRKQKEMKQDFEEQMALKE-LVLQAAKEEEENFRKTML 380

Query: 418 A 418
           A
Sbjct: 381 A 381



 Score = 30.8 bits (68), Expect = 2.5
 Identities = 39/205 (19%), Positives = 88/205 (42%), Gaps = 14/205 (6%)

Query: 188 NKVDEEFVEEETDNE-ENFIDLNVLKAQTYHLDMNETAKQEDILESTTDAAEWSLEVERV 246
           +++  + V+ E DN  +    L +L+ + + LDM E  ++    E      E  L+ E  
Sbjct: 36  SQIRNQMVQNENDNRVQRKQFLRLLQNEQFELDMEEAIQKA---EENKRLKELQLKQEEK 92

Query: 247 LPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLHNEITRTLEKISSREKY 306
           L      ++ ++    +  ++M Q        L+E +  L   +    R  + I+ ++  
Sbjct: 93  LAMELAKLKHES----LKDEKMRQQVRENSIELRELEKKLKAAYMNKERAAQ-IAEKDAI 147

Query: 307 INNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSS 366
              + E + ++   A+  + E K   ++ N    +R +  ++   +LEK  +E E+K   
Sbjct: 148 ---KYEQMKRDAEIAKTMMEEHKRIIKEENAAEDKRNKAKAQYYLDLEKQLEEQEKKKQE 204

Query: 367 MTDGAPLVKIKQSLTKLKQETVEMD 391
             +   L+K K  + ++ ++  E D
Sbjct: 205 AYE--QLLKEKLMIDEIVRKIYEED 227


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 53/276 (19%), Positives = 113/276 (40%), Gaps = 20/276 (7%)

Query: 153  EEALKYIGFTWKRPIYPVEELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLK 212
            EE  K +     +    + +LEE    E+     L K   +   E TD ++   +L   +
Sbjct: 1019 EEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAEL---Q 1075

Query: 213  AQTYHLDMNETAKQEDILESTTDAAEWSLEVE---RVLPQLKVTIRTDNKDWRIHVDQMH 269
            AQ   L +    K+E++  +     + +L      +V+ +L+  I    +D+    +   
Sbjct: 1076 AQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDF----ESEK 1131

Query: 270  QHRSGIESALKETKGFLDKLHNEITRTLEKISS-------REKYINNQLENLVQEYRAAQ 322
              R+  E   ++    L+ L  E+  TL+  ++       RE+ +    + L +E +  +
Sbjct: 1132 ASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHE 1191

Query: 323  AQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPL---VKIKQS 379
            AQ+ + ++R+      ++E+          LEK KQ +E     +     +   VK +  
Sbjct: 1192 AQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESE 1251

Query: 380  LTKLKQETVEMDIRIGIVEHTLLQSKLKEKSNMTRN 415
              + K +    ++   + E   L+ +L EK++  +N
Sbjct: 1252 HKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQN 1287



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 51/241 (21%), Positives = 105/241 (43%), Gaps = 30/241 (12%)

Query: 173  LEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVL---KAQTYHLDMNETAKQEDI 229
            LEE S   + A+     +++     ETDN+E   ++ VL   KA++ H      A+ +++
Sbjct: 1205 LEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQEL 1264

Query: 230  LESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMH-----QHRSGIESALKETKG 284
                ++     L VE      K+    DN    +   +       +  + +ES L++T+ 
Sbjct: 1265 HAKVSEGDR--LRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQE 1322

Query: 285  FLDKLHNEITRTLEKISSREKYINNQLE----------NLVQEYRAAQAQLSEAKERYQQ 334
             L +   +      +I   E+  N+  E          NL ++  A Q+QL++ K++   
Sbjct: 1323 LLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDD 1382

Query: 335  GNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQE----TVEM 390
              G +        +++++ E + Q +EEK  +        K++++  +L+QE    TV++
Sbjct: 1383 DLGTIESLEEAKKKLLKDAEALSQRLEEKALAYD------KLEKTKNRLQQELDDLTVDL 1436

Query: 391  D 391
            D
Sbjct: 1437 D 1437



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 58/268 (21%), Positives = 109/268 (40%), Gaps = 32/268 (11%)

Query: 171  EELEEESVAEDD-------AELTLNKVDEEFVEEETDN-----EENFIDLNVLKAQTYHL 218
            E+L+EE  A          AE  + K++EE +  E  N     E+  ++  + +  +   
Sbjct: 957  EQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLA 1016

Query: 219  DMNETAKQEDILESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRI--HVDQMHQHRSGIE 276
            +  E AK    + +  +     LE ER+  + K     +    ++      +    + ++
Sbjct: 1017 EEEEKAKNLAKIRNKQEVMISDLE-ERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQ 1075

Query: 277  SALKETKGFLDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGN 336
            + + E K  L K   E+   L +      + NN L+ +    R  QAQ++E +E ++   
Sbjct: 1076 AQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVV----RELQAQIAELQEDFESEK 1131

Query: 337  GGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSL-TKLKQETVEMDIRIG 395
                +  +   ++ EELE +K E+E       D       +Q L TK +QE  E  ++  
Sbjct: 1132 ASRNKAEKQKRDLSEELEALKTELE-------DTLDTTAAQQELRTKREQEVAE--LKKA 1182

Query: 396  IVEHTLLQSKLKEKSNMTRNMHATVIPE 423
            + E T      + +    R  HAT + E
Sbjct: 1183 LEEET---KNHEAQIQDMRQRHATALEE 1207



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 48/217 (22%), Positives = 98/217 (45%), Gaps = 31/217 (14%)

Query: 170  VEELEEESVAEDDAELTLN----KVDEEFVEE-ETDNEENFIDLNVLKAQTYHLD--MNE 222
            +EELE+E  A +DA+L L      +  +F  + +T +E+N     +L  Q   L+  + +
Sbjct: 1548 LEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELED 1607

Query: 223  TAKQEDILESTTDAAEWSLEV------------ERVLPQLKVTIRTDNKDWRIHVDQMHQ 270
              KQ  +  ++    E  L+             + V+ QL+  ++   KD++  +++   
Sbjct: 1608 ERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLR-KLQAQMKDYQRELEEARA 1666

Query: 271  HRSGIESALKETKGFLDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKE 330
             R  I +  KE++  L  L  EI +  E+++S E+   +  +         + +L++   
Sbjct: 1667 SRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQE--------RDELADEIT 1718

Query: 331  RYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSM 367
                G   + +  R L   + +LE   +E+EE+ S+M
Sbjct: 1719 NSASGKSALLDEKRRLEARIAQLE---EELEEEQSNM 1752



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 56/266 (21%), Positives = 117/266 (43%), Gaps = 34/266 (12%)

Query: 171  EELEEESVAEDDAELTLNKVDEE--FVEEETDNEENF---IDLNVLKAQTYHLDMNETAK 225
            E L+EE+  + +    + +++EE   ++E+ + EE     ++  VL  Q+   D  +   
Sbjct: 1322 ELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVD 1381

Query: 226  QE-DILESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKG 284
             +   +ES  +A +  L+    L Q     R + K   +  D++ + ++ ++  L +   
Sbjct: 1382 DDLGTIESLEEAKKKLLKDAEALSQ-----RLEEK--ALAYDKLEKTKNRLQQELDDLTV 1434

Query: 285  FLDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTR 344
             LD    ++   LEK   +        + L+ E ++  A+ +E ++R +        +  
Sbjct: 1435 DLDH-QRQVASNLEKKQKK-------FDQLLAEEKSISARYAEERDRAEAEAREKETKAL 1486

Query: 345  LLSEVMEELEKVKQE-----------MEEKGSSMTD-GAPLVKIKQSLTKLKQETVEMDI 392
             L+  +EE  + K+E           ME+  SS  D G  + ++++S   L+Q+  EM  
Sbjct: 1487 SLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRT 1546

Query: 393  RIGIVEHTLLQSKLKEKSNMTRNMHA 418
            ++  +E   LQ+    K  +  NM A
Sbjct: 1547 QLEELEDE-LQATEDAKLRLEVNMQA 1571



 Score = 30.0 bits (66), Expect = 4.2
 Identities = 39/216 (18%), Positives = 85/216 (39%), Gaps = 44/216 (20%)

Query: 171  EELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDIL 230
            + LEE+++A D  E T N++ +E        ++  +DL+  +    +L+  +    + + 
Sbjct: 1406 QRLEEKALAYDKLEKTKNRLQQEL-------DDLTVDLDHQRQVASNLEKKQKKFDQLLA 1458

Query: 231  ESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLH 290
            E  + +A ++ E                           + R+  E+  KETK       
Sbjct: 1459 EEKSISARYAEE---------------------------RDRAEAEAREKETKAL----- 1486

Query: 291  NEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVM 350
              + R LE+    ++    Q + L    RA    L  +K+   +    + +  R L + +
Sbjct: 1487 -SLARALEEALEAKEEFERQNKQL----RADMEDLMSSKDDVGKNVHELEKSKRALEQQV 1541

Query: 351  EELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQE 386
            EE+    +E+E++  +  D    +++     K + E
Sbjct: 1542 EEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFE 1577


>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
          Length = 1710

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 53/252 (21%), Positives = 111/252 (44%), Gaps = 20/252 (7%)

Query: 184  ELTLNKVDEEFVEEETDNEEN--FIDLNVLKAQTYHLDMNETAKQ-EDILESTTDAAEWS 240
            E+ + +++ + ++ +   +E   F DL ++K +    D+ +T KQ E+ L  T       
Sbjct: 920  EIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNE--DLQKTIKQNEETLTQTISQYNGR 977

Query: 241  LEV---ERVLPQLKVTIRTDNKD-WRIHVDQMHQH-------RSGIESALKETKGFLDKL 289
            L V   E  +   K+     +K+     V+  H         R   E++ +E +    + 
Sbjct: 978  LSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRA 1037

Query: 290  HNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEV 349
             +E +R  +K++     + +  E L Q+    +++L+  +  +      + E+T  L  V
Sbjct: 1038 RDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERV 1097

Query: 350  MEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQETVEMDIRIGIVEHTLLQSKLKEK 409
             ++L + + +M+E      +    VK+ + +   KQE+VE  +     E+ LL+ +L + 
Sbjct: 1098 QKDLSQTQCQMKEMEQKYQN--EQVKVNKYIG--KQESVEERLSQLQSENMLLRQQLDDA 1153

Query: 410  SNMTRNMHATVI 421
             N   N   TVI
Sbjct: 1154 HNKADNKEKTVI 1165



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 45/203 (22%), Positives = 91/203 (44%), Gaps = 26/203 (12%)

Query: 212 KAQTYHLDMNETAKQEDILESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMH-- 269
           K      +++ET + +  LE      EW    ER L  L+ ++  + +  R + D ++  
Sbjct: 759 KVNVLQRELSETKEIKSQLEH--QKVEW----ERELCSLRFSLNQEEEKRR-NADTLYEK 811

Query: 270 ---QHRSGIESALKETKGFLDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLS 326
              Q R   E   KE +     +  ++  +L+ +    + + + L  +VQE   AQ QLS
Sbjct: 812 IREQLRRKEEQYRKEVE-----VKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLS 866

Query: 327 EAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQE 386
             +      +G +T     LS+  +E+E  +++M  + S   +    +  K S+  L++E
Sbjct: 867 REQNARMLQDGILTNH---LSK-QKEIEMAQKKMNSENSHSHEEEKDLSHKNSM--LQEE 920

Query: 387 TVEMDIRIGIVEHTLLQSKLKEK 409
              + + I  +++   Q++ KEK
Sbjct: 921 IAMLRLEIDTIKN---QNQEKEK 940


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.130    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,011,202
Number of Sequences: 37866
Number of extensions: 733986
Number of successful extensions: 4656
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 118
Number of HSP's successfully gapped in prelim test: 449
Number of HSP's that attempted gapping in prelim test: 3336
Number of HSP's gapped (non-prelim): 1485
length of query: 429
length of database: 18,247,518
effective HSP length: 105
effective length of query: 324
effective length of database: 14,271,588
effective search space: 4623994512
effective search space used: 4623994512
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.