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Search of human proteins with 89111122
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|89111122 Toll-interleukin 1 receptor domain-containing
adaptor protein isoform a [Homo sapiens]
(221 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|89111122 Toll-interleukin 1 receptor domain-containing adapto... 452 e-127
gi|22547219 Toll-interleukin 1 receptor domain-containing adapto... 441 e-124
gi|197276654 myeloid differentiation primary response gene 88 [H... 52 3e-07
gi|19718734 toll-like receptor 2 [Homo sapiens] 49 4e-06
gi|20143971 toll-like receptor 6 [Homo sapiens] 43 2e-04
gi|41281981 toll-like receptor adaptor molecule 1 [Homo sapiens] 39 0.005
gi|41350337 toll-like receptor 1 [Homo sapiens] 37 0.013
gi|62865621 toll-like receptor 10 precursor [Homo sapiens] 37 0.013
gi|62865618 toll-like receptor 10 precursor [Homo sapiens] 37 0.013
gi|41282048 pyrin and HIN domain family, member 1 alpha 2 isofor... 37 0.013
gi|39540514 pyrin and HIN domain family, member 1 alpha 1 isofor... 37 0.013
gi|16751843 toll-like receptor 5 [Homo sapiens] 37 0.017
gi|67906195 ankyrin repeat and sterile alpha motif domain contai... 36 0.023
gi|34996489 pleckstrin homology domain interacting protein [Homo... 36 0.030
gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sap... 34 0.11
gi|157739864 ubiquitination factor E4B isoform 1 [Homo sapiens] 34 0.11
gi|116284392 mucin 2 precursor [Homo sapiens] 33 0.15
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 33 0.15
gi|226817313 SH3 and multiple ankyrin repeat domains 2 isoform 1... 33 0.15
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 33 0.15
gi|4504655 interleukin 18 receptor 1 precursor [Homo sapiens] 33 0.19
gi|169163027 PREDICTED: similar to Putative acrosin-like proteas... 33 0.19
gi|148613878 acrosin precursor [Homo sapiens] 33 0.19
gi|223633988 hypothetical protein LOC85379 [Homo sapiens] 33 0.25
gi|33386674 toll-like receptor adaptor molecule 2 [Homo sapiens] 33 0.25
gi|21735550 mitogen-activated protein kinase kinase kinase 10 [H... 33 0.25
gi|150417978 platelet glycoprotein Ib alpha polypeptide precurso... 32 0.33
gi|169164209 PREDICTED: hypothetical protein [Homo sapiens] 32 0.43
gi|239741571 PREDICTED: hypothetical protein XP_002342241 [Homo ... 32 0.43
gi|31543452 PX domain containing serine/threonine kinase [Homo s... 32 0.43
>gi|89111122 Toll-interleukin 1 receptor domain-containing adaptor
protein isoform a [Homo sapiens]
Length = 221
Score = 452 bits (1162), Expect = e-127
Identities = 221/221 (100%), Positives = 221/221 (100%)
Query: 1 MASSTSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPS 60
MASSTSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPS
Sbjct: 1 MASSTSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPS 60
Query: 61 LSSVTSPSLPPTHASDSGSSRWSKDYDVCVCHSEEDLVAAQDLVSYLEGSTASLRCFLQL 120
LSSVTSPSLPPTHASDSGSSRWSKDYDVCVCHSEEDLVAAQDLVSYLEGSTASLRCFLQL
Sbjct: 61 LSSVTSPSLPPTHASDSGSSRWSKDYDVCVCHSEEDLVAAQDLVSYLEGSTASLRCFLQL 120
Query: 121 RDATPGGAIVSELCQALSSSHCRVLLITPGFLQDPWCKYQMLQALTEAPGAEGCTIPLLS 180
RDATPGGAIVSELCQALSSSHCRVLLITPGFLQDPWCKYQMLQALTEAPGAEGCTIPLLS
Sbjct: 121 RDATPGGAIVSELCQALSSSHCRVLLITPGFLQDPWCKYQMLQALTEAPGAEGCTIPLLS 180
Query: 181 GLSRAAYPPELRFMYYVDGRGPDGGFRQVKEAVMRYLQTLS 221
GLSRAAYPPELRFMYYVDGRGPDGGFRQVKEAVMRYLQTLS
Sbjct: 181 GLSRAAYPPELRFMYYVDGRGPDGGFRQVKEAVMRYLQTLS 221
>gi|22547219 Toll-interleukin 1 receptor domain-containing adaptor
protein isoform b [Homo sapiens]
Length = 235
Score = 441 bits (1133), Expect = e-124
Identities = 215/215 (100%), Positives = 215/215 (100%)
Query: 1 MASSTSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPS 60
MASSTSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPS
Sbjct: 1 MASSTSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPS 60
Query: 61 LSSVTSPSLPPTHASDSGSSRWSKDYDVCVCHSEEDLVAAQDLVSYLEGSTASLRCFLQL 120
LSSVTSPSLPPTHASDSGSSRWSKDYDVCVCHSEEDLVAAQDLVSYLEGSTASLRCFLQL
Sbjct: 61 LSSVTSPSLPPTHASDSGSSRWSKDYDVCVCHSEEDLVAAQDLVSYLEGSTASLRCFLQL 120
Query: 121 RDATPGGAIVSELCQALSSSHCRVLLITPGFLQDPWCKYQMLQALTEAPGAEGCTIPLLS 180
RDATPGGAIVSELCQALSSSHCRVLLITPGFLQDPWCKYQMLQALTEAPGAEGCTIPLLS
Sbjct: 121 RDATPGGAIVSELCQALSSSHCRVLLITPGFLQDPWCKYQMLQALTEAPGAEGCTIPLLS 180
Query: 181 GLSRAAYPPELRFMYYVDGRGPDGGFRQVKEAVMR 215
GLSRAAYPPELRFMYYVDGRGPDGGFRQVKEAVMR
Sbjct: 181 GLSRAAYPPELRFMYYVDGRGPDGGFRQVKEAVMR 215
>gi|197276654 myeloid differentiation primary response gene 88 [Homo
sapiens]
Length = 309
Score = 52.4 bits (124), Expect = 3e-07
Identities = 43/178 (24%), Positives = 81/178 (45%), Gaps = 19/178 (10%)
Query: 29 LLKKPKKRPNSPESTSS-DASQPTSQDSPLPPSLSSVTSPSLPPTHASDSGSSRWSKDYD 87
+LK+ ++ P ++ D+S P + + L+ +T+ P H + +D
Sbjct: 130 ILKQQQEEAEKPLQVAAVDSSVPRTAE------LAGITTLDDPLGHMPER--------FD 175
Query: 88 VCVCHSEEDLVAAQDLVSYLEGSTASLRCFLQLRDATPGGAIVSELCQALSSSHCR--VL 145
+C+ D+ Q+++ LE + L+ + RD PG + S + L CR V+
Sbjct: 176 AFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWS-IASELIEKRCRRMVV 234
Query: 146 LITPGFLQDPWCKYQMLQALTEAPGA-EGCTIPLLSGLSRAAYPPELRFMYYVDGRGP 202
+++ +LQ C +Q AL+ +PGA + IP+ + +P LRF+ D P
Sbjct: 235 VVSDDYLQSKECDFQTKFALSLSPGAHQKRLIPIKYKAMKKEFPSILRFITVCDYTNP 292
>gi|19718734 toll-like receptor 2 [Homo sapiens]
Length = 784
Score = 48.5 bits (114), Expect = 4e-06
Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 1/77 (1%)
Query: 86 YDVCVCHSEEDLVAAQDL-VSYLEGSTASLRCFLQLRDATPGGAIVSELCQALSSSHCRV 144
YD V +SE D ++L V LE + L RD PG I+ + ++ SH V
Sbjct: 641 YDAFVSYSERDAYWVENLMVQELENFNPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKTV 700
Query: 145 LLITPGFLQDPWCKYQM 161
+++ F++ WCKY++
Sbjct: 701 FVLSENFVKSEWCKYEL 717
>gi|20143971 toll-like receptor 6 [Homo sapiens]
Length = 796
Score = 42.7 bits (99), Expect = 2e-04
Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
Query: 90 VCHSEEDLV-AAQDLVSYLEGSTASLRCFLQLRDATPGGAIVSELCQALSSSHCRVLLIT 148
+ +SE D +LV YLE ++ L R+ PG +IV + + S+ + +++
Sbjct: 646 ISYSEHDSAWVKSELVPYLEKE--DIQICLHERNFVPGKSIVENIINCIEKSYKSIFVLS 703
Query: 149 PGFLQDPWCKYQM 161
P F+Q WC Y++
Sbjct: 704 PNFVQSEWCHYEL 716
>gi|41281981 toll-like receptor adaptor molecule 1 [Homo sapiens]
Length = 712
Score = 38.5 bits (88), Expect = 0.005
Identities = 49/183 (26%), Positives = 66/183 (36%), Gaps = 6/183 (3%)
Query: 2 ASSTSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPSL 61
A SLP P P K + D L + PN+ + + TS P PP
Sbjct: 309 AGPQSLPLPILEPVKNPCSVKDQTPLQLSVEDTTSPNTKPCPPTPTTPETSPPPPPPPPS 368
Query: 62 SSVTSPSLPPTHASDSG--SSRWSKDYDVCVCHSEEDLVAAQDLVSYLEGSTASLRCFLQ 119
S+ S L P+ S SS K Y+ + H+ D A + LE
Sbjct: 369 STPCSAHLTPSSLFPSSLESSSEQKFYNFVILHARADEHIALRVREKLEALGVPDGATFC 428
Query: 120 LRDATPGGAIVSELCQALSSSHCRVLLITPGF---LQDPWCKYQMLQALTEAPGAEGCTI 176
PG +S L A+ S +LL+T F L M+ LT G+ C I
Sbjct: 429 EDFQVPGRGELSCLQDAIDHSAFIILLLTSNFDCRLSLHQVNQAMMSNLTR-QGSPDCVI 487
Query: 177 PLL 179
P L
Sbjct: 488 PFL 490
>gi|41350337 toll-like receptor 1 [Homo sapiens]
Length = 786
Score = 37.0 bits (84), Expect = 0.013
Identities = 13/44 (29%), Positives = 25/44 (56%)
Query: 118 LQLRDATPGGAIVSELCQALSSSHCRVLLITPGFLQDPWCKYQM 161
L R+ PG +IV + + S+ + +++P F+Q WC Y++
Sbjct: 668 LHERNFVPGKSIVENIITCIEKSYKSIFVLSPNFVQSEWCHYEL 711
>gi|62865621 toll-like receptor 10 precursor [Homo sapiens]
Length = 811
Score = 37.0 bits (84), Expect = 0.013
Identities = 19/72 (26%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
Query: 90 VCHSEED-LVAAQDLVSYLEGSTASLRCFLQLRDATPGGAIVSELCQALSSSHCRVLLIT 148
+ +SE D L +L+ LE S+ L PG +I + + S+ + +++
Sbjct: 638 ISYSEHDSLWVKNELIPNLEKEDGSILICLYESYFDPGKSISENIVSFIEKSYKSIFVLS 697
Query: 149 PGFLQDPWCKYQ 160
P F+Q+ WC Y+
Sbjct: 698 PNFVQNEWCHYE 709
>gi|62865618 toll-like receptor 10 precursor [Homo sapiens]
Length = 811
Score = 37.0 bits (84), Expect = 0.013
Identities = 19/72 (26%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
Query: 90 VCHSEED-LVAAQDLVSYLEGSTASLRCFLQLRDATPGGAIVSELCQALSSSHCRVLLIT 148
+ +SE D L +L+ LE S+ L PG +I + + S+ + +++
Sbjct: 638 ISYSEHDSLWVKNELIPNLEKEDGSILICLYESYFDPGKSISENIVSFIEKSYKSIFVLS 697
Query: 149 PGFLQDPWCKYQ 160
P F+Q+ WC Y+
Sbjct: 698 PNFVQNEWCHYE 709
>gi|41282048 pyrin and HIN domain family, member 1 alpha 2 isoform
[Homo sapiens]
Length = 483
Score = 37.0 bits (84), Expect = 0.013
Identities = 22/78 (28%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
Query: 4 STSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPSLSS 63
S +LP S+ KP + + ++ LK P+ P +P S+S T + P+
Sbjct: 402 SMALPQEQSQHPKP-SEASTTLPESHLKTPQMPPTTPSSSSFTKKDETHPGAQSSPANFR 460
Query: 64 VTSPSLPPTHASDSGSSR 81
+TSP++ P +SD+ ++R
Sbjct: 461 ITSPTVAPPLSSDTSTNR 478
>gi|39540514 pyrin and HIN domain family, member 1 alpha 1 isoform
[Homo sapiens]
Length = 492
Score = 37.0 bits (84), Expect = 0.013
Identities = 22/78 (28%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
Query: 4 STSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPSLSS 63
S +LP S+ KP + + ++ LK P+ P +P S+S T + P+
Sbjct: 411 SMALPQEQSQHPKP-SEASTTLPESHLKTPQMPPTTPSSSSFTKKDETHPGAQSSPANFR 469
Query: 64 VTSPSLPPTHASDSGSSR 81
+TSP++ P +SD+ ++R
Sbjct: 470 ITSPTVAPPLSSDTSTNR 487
>gi|16751843 toll-like receptor 5 [Homo sapiens]
Length = 858
Score = 36.6 bits (83), Expect = 0.017
Identities = 26/89 (29%), Positives = 44/89 (49%), Gaps = 8/89 (8%)
Query: 86 YDVCVCHSEEDLVAAQD-LVSYLEGSTASLRCF---LQLRDATPGGAIVSELCQALSSSH 141
YD +C S +D Q+ L+ +L+ + F + RD PG ++ + A+ +S
Sbjct: 693 YDAYLCFSSKDFTWVQNALLKHLDTQYSDQNRFNLCFEERDFVPGENRIANIQDAIWNSR 752
Query: 142 CRVLLITPGFLQDPWCKYQMLQALTEAPG 170
V L++ FL+D WC L+A + A G
Sbjct: 753 KIVCLVSRHFLRDGWC----LEAFSYAQG 777
>gi|67906195 ankyrin repeat and sterile alpha motif domain
containing 6 [Homo sapiens]
Length = 871
Score = 36.2 bits (82), Expect = 0.023
Identities = 32/85 (37%), Positives = 41/85 (48%), Gaps = 10/85 (11%)
Query: 3 SSTSLPAPGSRPKK----PLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLP 58
SS PAPGS P + P G A ++ + KRP S ST+S ++ PT SP P
Sbjct: 687 SSPVGPAPGSSPSELPASPAGGSAPVGKKL---ETSKRPPSGTSTTSKSTSPTLTPSPSP 743
Query: 59 ---PSLSSVTSPSLPPTHASDSGSS 80
+ SSV+S S S GSS
Sbjct: 744 KGHTAESSVSSSSSHRQSKSSGGSS 768
>gi|34996489 pleckstrin homology domain interacting protein [Homo
sapiens]
Length = 1821
Score = 35.8 bits (81), Expect = 0.030
Identities = 38/139 (27%), Positives = 61/139 (43%), Gaps = 24/139 (17%)
Query: 26 RQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPSLSSVTSP--------SLPPTH--AS 75
R T+ K+ KKR S +SS AS P + L P L S +S S+PP H A
Sbjct: 1434 RNTITKRRKKRNRSSSVSSSAASSPERKKRILKPQLKSESSTSAFSTPTRSIPPRHNAAQ 1493
Query: 76 DSGSSRWSKDYDVCVCHSEEDLVAAQDLVSYLEGSTASLRCFLQLRDAT--PGGAIVSEL 133
+G + S V + + V +V+ ++++ + F+ +A+ PG I+
Sbjct: 1494 INGKTESSS-----VVRTRSNRVVVDPVVTEQPSTSSAAKTFITKANASAIPGKTILEN- 1547
Query: 134 CQALSSSHCRVL--LITPG 150
S H + L L +PG
Sbjct: 1548 ----SVKHSKALNTLSSPG 1562
>gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo
sapiens]
Length = 1258
Score = 33.9 bits (76), Expect = 0.11
Identities = 25/80 (31%), Positives = 34/80 (42%), Gaps = 9/80 (11%)
Query: 7 LPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPSLSSVTS 66
LP G R P R + +K P P S S+ S PT SPLP + +
Sbjct: 115 LPVEGEREPDPPDD-----RDASDGEDEKPPLPPRSGSTSISAPTGPSSPLP----APET 165
Query: 67 PSLPPTHASDSGSSRWSKDY 86
P+ P ++ +G S S DY
Sbjct: 166 PTAPAAESAPNGLSTVSHDY 185
>gi|157739864 ubiquitination factor E4B isoform 1 [Homo sapiens]
Length = 1302
Score = 33.9 bits (76), Expect = 0.11
Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 11/82 (13%)
Query: 33 PKKRPNSPEST--SSDASQPTSQDSPLPPSLSSVTS--PS---LPPTHASDSGSSRWSKD 85
P +SP++ SS +P+S PLPP+ S TS PS + P+ + G+S W
Sbjct: 353 PPALASSPQAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISPSLGASGGASNWDSY 412
Query: 86 YDVCVCHSEEDLVAAQDLVSYL 107
D H + D+++YL
Sbjct: 413 SD----HFTIETCKETDMLNYL 430
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 33.5 bits (75), Expect = 0.15
Identities = 21/78 (26%), Positives = 34/78 (43%), Gaps = 8/78 (10%)
Query: 3 SSTSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSS----DASQPTSQDSPLP 58
++T+ P P + P P+ T P P+ P +T S + P +P P
Sbjct: 1443 TTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSP 1502
Query: 59 PSLSSVTSP----SLPPT 72
P+ + +T P +LPPT
Sbjct: 1503 PTTTPITPPASTTTLPPT 1520
Score = 33.1 bits (74), Expect = 0.19
Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 11/84 (13%)
Query: 3 SSTSLPAPGSRPKKPLGKMADWFRQTLLK-KPKKRPNSP-------ESTSSDASQPTSQD 54
++T+ P P + P P+ T+ P P+SP ST++ + PT+
Sbjct: 1670 TTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMT 1729
Query: 55 SPLP---PSLSSVTSPSLPPTHAS 75
+P P PS + T +LPPT S
Sbjct: 1730 TPSPTTTPSPPTTTMTTLPPTTTS 1753
Score = 32.7 bits (73), Expect = 0.25
Identities = 21/74 (28%), Positives = 34/74 (45%), Gaps = 6/74 (8%)
Query: 3 SSTSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPSLS 62
++T+ P P + P P T P SP +T++ PT+ +P PP+ +
Sbjct: 1567 TTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTT--TPSPPTTT 1624
Query: 63 SVTSP----SLPPT 72
+T P +LPPT
Sbjct: 1625 PITPPTSTTTLPPT 1638
Score = 32.0 bits (71), Expect = 0.43
Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 7/74 (9%)
Query: 3 SSTSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPSLS 62
++T+ P P + P P T P P SP +T++ PT+ +P PP+ +
Sbjct: 1489 TTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTP-SPPTTTTTTPPPTT--TPSPPTTT 1545
Query: 63 SVTSP----SLPPT 72
+T P +LPPT
Sbjct: 1546 PITPPTSTTTLPPT 1559
Score = 28.9 bits (63), Expect = 3.6
Identities = 16/44 (36%), Positives = 24/44 (54%), Gaps = 2/44 (4%)
Query: 37 PNSPESTSSDASQPTSQDSPLPPS--LSSVTSPSLPPTHASDSG 78
P + STSS ++ T+ S LPP+ ++S PS P + SG
Sbjct: 4221 PQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSG 4264
>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
Length = 1970
Score = 33.5 bits (75), Expect = 0.15
Identities = 30/82 (36%), Positives = 38/82 (46%), Gaps = 11/82 (13%)
Query: 1 MASSTSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPE-STSSDASQPTSQD-SPLP 58
M+ S S +P P+ P G + P P SP S +S + PTS + SP
Sbjct: 1589 MSPSYSPTSPAYEPRSPGGYTP--------QSPSYSPTSPSYSPTSPSYSPTSPNYSPTS 1640
Query: 59 PSLSSVTSPSLPPTHASDSGSS 80
PS S TSPS PT S S +S
Sbjct: 1641 PSYSP-TSPSYSPTSPSYSPTS 1661
Score = 29.6 bits (65), Expect = 2.1
Identities = 23/50 (46%), Positives = 26/50 (52%), Gaps = 3/50 (6%)
Query: 33 PKKRPNSPE-STSSDASQPTSQD-SPLPPSLSSVTSPSLPPTHASDSGSS 80
P P SP S +S + PTS SP PS S TSPS PT S S +S
Sbjct: 1634 PNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPTS 1682
Score = 29.6 bits (65), Expect = 2.1
Identities = 23/50 (46%), Positives = 26/50 (52%), Gaps = 3/50 (6%)
Query: 33 PKKRPNSPE-STSSDASQPTSQD-SPLPPSLSSVTSPSLPPTHASDSGSS 80
P P SP S +S + PTS SP PS S TSPS PT S S +S
Sbjct: 1641 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPTS 1689
Score = 29.6 bits (65), Expect = 2.1
Identities = 23/50 (46%), Positives = 26/50 (52%), Gaps = 3/50 (6%)
Query: 33 PKKRPNSPE-STSSDASQPTSQD-SPLPPSLSSVTSPSLPPTHASDSGSS 80
P P SP S +S + PTS SP PS S TSPS PT S S +S
Sbjct: 1648 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPTS 1696
Score = 29.6 bits (65), Expect = 2.1
Identities = 23/50 (46%), Positives = 26/50 (52%), Gaps = 3/50 (6%)
Query: 33 PKKRPNSPE-STSSDASQPTSQD-SPLPPSLSSVTSPSLPPTHASDSGSS 80
P P SP S +S + PTS SP PS S TSPS PT S S +S
Sbjct: 1655 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPTS 1703
Score = 29.6 bits (65), Expect = 2.1
Identities = 23/50 (46%), Positives = 26/50 (52%), Gaps = 3/50 (6%)
Query: 33 PKKRPNSPE-STSSDASQPTSQD-SPLPPSLSSVTSPSLPPTHASDSGSS 80
P P SP S +S + PTS SP PS S TSPS PT S S +S
Sbjct: 1662 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPTS 1710
Score = 29.6 bits (65), Expect = 2.1
Identities = 23/50 (46%), Positives = 26/50 (52%), Gaps = 3/50 (6%)
Query: 33 PKKRPNSPE-STSSDASQPTSQD-SPLPPSLSSVTSPSLPPTHASDSGSS 80
P P SP S +S + PTS SP PS S TSPS PT S S +S
Sbjct: 1669 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPTS 1717
Score = 29.6 bits (65), Expect = 2.1
Identities = 23/50 (46%), Positives = 26/50 (52%), Gaps = 3/50 (6%)
Query: 33 PKKRPNSPE-STSSDASQPTSQD-SPLPPSLSSVTSPSLPPTHASDSGSS 80
P P SP S +S + PTS SP PS S TSPS PT S S +S
Sbjct: 1676 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPTS 1724
Score = 29.6 bits (65), Expect = 2.1
Identities = 23/50 (46%), Positives = 26/50 (52%), Gaps = 3/50 (6%)
Query: 33 PKKRPNSPE-STSSDASQPTSQD-SPLPPSLSSVTSPSLPPTHASDSGSS 80
P P SP S +S + PTS SP PS S TSPS PT S S +S
Sbjct: 1683 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPTS 1731
Score = 29.6 bits (65), Expect = 2.1
Identities = 23/50 (46%), Positives = 26/50 (52%), Gaps = 3/50 (6%)
Query: 33 PKKRPNSPE-STSSDASQPTSQD-SPLPPSLSSVTSPSLPPTHASDSGSS 80
P P SP S +S + PTS SP PS S TSPS PT S S +S
Sbjct: 1690 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPTS 1738
Score = 29.6 bits (65), Expect = 2.1
Identities = 23/50 (46%), Positives = 26/50 (52%), Gaps = 3/50 (6%)
Query: 33 PKKRPNSPE-STSSDASQPTSQD-SPLPPSLSSVTSPSLPPTHASDSGSS 80
P P SP S +S + PTS SP PS S TSPS PT S S +S
Sbjct: 1697 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPTS 1745
Score = 29.6 bits (65), Expect = 2.1
Identities = 24/50 (48%), Positives = 26/50 (52%), Gaps = 3/50 (6%)
Query: 33 PKKRPNSPE-STSSDASQPTSQD-SPLPPSLSSVTSPSLPPTHASDSGSS 80
P P SP S +S PTS + SP PS S TSPS PT S S SS
Sbjct: 1760 PSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSP-TSPSYSPTSPSYSPSS 1808
Score = 28.5 bits (62), Expect = 4.7
Identities = 22/50 (44%), Positives = 26/50 (52%), Gaps = 3/50 (6%)
Query: 33 PKKRPNSPE-STSSDASQPTSQD-SPLPPSLSSVTSPSLPPTHASDSGSS 80
P P SP S +S + PTS SP PS S TSPS PT + S +S
Sbjct: 1704 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPNYSPTS 1752
Score = 27.7 bits (60), Expect = 8.1
Identities = 21/50 (42%), Positives = 27/50 (54%), Gaps = 3/50 (6%)
Query: 33 PKKRPNSPE-STSSDASQPTSQD-SPLPPSLSSVTSPSLPPTHASDSGSS 80
P P SP S +S + PTS + SP P+ + TSPS PT S S +S
Sbjct: 1725 PSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTP-TSPSYSPTSPSYSPTS 1773
Score = 27.7 bits (60), Expect = 8.1
Identities = 21/50 (42%), Positives = 27/50 (54%), Gaps = 3/50 (6%)
Query: 33 PKKRPNSPE-STSSDASQPTSQD-SPLPPSLSSVTSPSLPPTHASDSGSS 80
P P SP S +S + PTS + +P P+ S TSPS PT S S +S
Sbjct: 1753 PNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSP-TSPSYSPTSPSYSPTS 1801
>gi|226817313 SH3 and multiple ankyrin repeat domains 2 isoform 1
[Homo sapiens]
Length = 1849
Score = 33.5 bits (75), Expect = 0.15
Identities = 21/56 (37%), Positives = 34/56 (60%), Gaps = 2/56 (3%)
Query: 34 KKRPNSPESTSSDASQPT-SQDSPLPPSLSSVTSPS-LPPTHASDSGSSRWSKDYD 87
+K+ ++P+S S ++SQPT S DS P SLS+ S LPP + D+ + ++ D
Sbjct: 1440 QKKSDTPQSPSLNSSQPTNSADSKKPASLSNCLPASFLPPPESFDAVADSGIEEVD 1495
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 33.5 bits (75), Expect = 0.15
Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Query: 3 SSTSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLP--PS 60
S S P+ G++P PL + Q +P+ +P P+ P++ +P+P P
Sbjct: 2371 SDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSPL 2430
Query: 61 LSSVTS--PSLPP 71
S+TS SLPP
Sbjct: 2431 QISMTSLQNSLPP 2443
Score = 27.7 bits (60), Expect = 8.1
Identities = 16/41 (39%), Positives = 18/41 (43%), Gaps = 2/41 (4%)
Query: 33 PKKRPNSPESTSSDASQPTSQDSPLPPS--LSSVTSPSLPP 71
P P P S P S D PL PS + V P+LPP
Sbjct: 2008 PPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPP 2048
>gi|4504655 interleukin 18 receptor 1 precursor [Homo sapiens]
Length = 541
Score = 33.1 bits (74), Expect = 0.19
Identities = 20/77 (25%), Positives = 37/77 (48%), Gaps = 2/77 (2%)
Query: 92 HSEEDLVAAQDLVSYLEGSTASLRCFLQLRDATPGGAIVSELCQALSSSHCRVLLITPGF 151
+ EE A + L LE C + RD PGGA+V E+ + S +++++ +
Sbjct: 389 NGEEHTFAVEILPRVLEKHFGYKLCIFE-RDVVPGGAVVDEIHSLIEKSRRLIIVLSKSY 447
Query: 152 LQDPWCKYQMLQALTEA 168
+ + +Y++ L EA
Sbjct: 448 MSNE-VRYELESGLHEA 463
>gi|169163027 PREDICTED: similar to Putative acrosin-like protease
[Homo sapiens]
Length = 355
Score = 33.1 bits (74), Expect = 0.19
Identities = 23/78 (29%), Positives = 29/78 (37%), Gaps = 12/78 (15%)
Query: 1 MASSTSLPAPGSRP-------KKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQ 53
M S + P P +RP PL W+ Q P RP P ++ P S
Sbjct: 230 MIQSATPPPPTTRPPPIRPPFSHPLSAHLPWYFQ-----PPPRPLPPRPPAAQPRPPPSP 284
Query: 54 DSPLPPSLSSVTSPSLPP 71
P PP S + P PP
Sbjct: 285 PPPPPPPPSPLPPPPPPP 302
>gi|148613878 acrosin precursor [Homo sapiens]
Length = 421
Score = 33.1 bits (74), Expect = 0.19
Identities = 22/78 (28%), Positives = 29/78 (37%), Gaps = 12/78 (15%)
Query: 1 MASSTSLPAPGSRP-------KKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQ 53
M S + P P +RP P+ W+ Q P RP P ++ P S
Sbjct: 296 MIQSATPPPPTTRPPPIRPPFSHPISAHLPWYFQ-----PPPRPLPPRPPAAQPRPPPSP 350
Query: 54 DSPLPPSLSSVTSPSLPP 71
P PP S + P PP
Sbjct: 351 PPPPPPPASPLPPPPPPP 368
>gi|223633988 hypothetical protein LOC85379 [Homo sapiens]
Length = 1806
Score = 32.7 bits (73), Expect = 0.25
Identities = 22/55 (40%), Positives = 27/55 (49%), Gaps = 4/55 (7%)
Query: 35 KRP--NSPESTSSDASQPTSQDSPLPPSL--SSVTSPSLPPTHASDSGSSRWSKD 85
KRP +SP T S A QP S SP P + S V S+ SD S +W K+
Sbjct: 1738 KRPEVDSPGETPSWAPQPKSPKSPFQPGVLGSRVLPSSMDKDERSDEPSPQWLKE 1792
>gi|33386674 toll-like receptor adaptor molecule 2 [Homo sapiens]
Length = 235
Score = 32.7 bits (73), Expect = 0.25
Identities = 19/76 (25%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Query: 90 VCHSEEDLVAAQDLVSYLEGSTASLRCFLQLRDATPGGAIVSELCQALSSSHCRVLLITP 149
+ H+E+D A + + L+ ++ + + G + L A++ S +LL+T
Sbjct: 83 ILHAEDDTDEALRVQNLLQDDFG-IKPGIIFAEMPCGRQHLQNLDDAVNGSAWTILLLTE 141
Query: 150 GFLQDPWCKYQMLQAL 165
FL+D WC +Q +L
Sbjct: 142 NFLRDTWCNFQFYTSL 157
>gi|21735550 mitogen-activated protein kinase kinase kinase 10 [Homo
sapiens]
Length = 954
Score = 32.7 bits (73), Expect = 0.25
Identities = 20/63 (31%), Positives = 27/63 (42%), Gaps = 4/63 (6%)
Query: 9 APGSRPKKPLGKMADW----FRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPSLSSV 64
AP RP ++ W F +TL P RP++PES + QPT D +
Sbjct: 884 APRPRPAASRPRLDPWKLVSFGRTLTISPPSRPDTPESPGPPSVQPTLLDMDMEGQNQDS 943
Query: 65 TSP 67
T P
Sbjct: 944 TVP 946
>gi|150417978 platelet glycoprotein Ib alpha polypeptide precursor
[Homo sapiens]
Length = 639
Score = 32.3 bits (72), Expect = 0.33
Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 4/73 (5%)
Query: 4 STSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPSLSS 63
ST+ P P +P+ + A T L+ P P +PE TS A PT+ + P+ S
Sbjct: 378 STTEPTPSPTTSEPVPEPAP--NMTTLE-PTPSPTTPEPTSEPAPSPTTPEPTSEPAPSP 434
Query: 64 VTSPSLP-PTHAS 75
T P PT A+
Sbjct: 435 TTPEPTPIPTIAT 447
>gi|169164209 PREDICTED: hypothetical protein [Homo sapiens]
Length = 179
Score = 32.0 bits (71), Expect = 0.43
Identities = 20/55 (36%), Positives = 24/55 (43%), Gaps = 3/55 (5%)
Query: 29 LLKKPKKRPNSPESTSSDASQPTSQDSPLP---PSLSSVTSPSLPPTHASDSGSS 80
+L P P +P + P S P P PS S P LPP+HAS S S
Sbjct: 14 ILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRS 68
>gi|239741571 PREDICTED: hypothetical protein XP_002342241 [Homo
sapiens]
Length = 179
Score = 32.0 bits (71), Expect = 0.43
Identities = 20/55 (36%), Positives = 24/55 (43%), Gaps = 3/55 (5%)
Query: 29 LLKKPKKRPNSPESTSSDASQPTSQDSPLP---PSLSSVTSPSLPPTHASDSGSS 80
+L P P +P + P S P P PS S P LPP+HAS S S
Sbjct: 14 ILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRS 68
>gi|31543452 PX domain containing serine/threonine kinase [Homo
sapiens]
Length = 578
Score = 32.0 bits (71), Expect = 0.43
Identities = 18/38 (47%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
Query: 35 KRPNSPESTSSDASQP-TSQDSPLPPSLSSVTSPSLPP 71
K NS S S AS P TS SP PPS S +++ PP
Sbjct: 481 KYSNSNNSAGSGASSPLTSPSSPTPPSTSGISALPPPP 518
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,422,607
Number of Sequences: 37866
Number of extensions: 519779
Number of successful extensions: 4028
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 72
Number of HSP's successfully gapped in prelim test: 180
Number of HSP's that attempted gapping in prelim test: 3513
Number of HSP's gapped (non-prelim): 684
length of query: 221
length of database: 18,247,518
effective HSP length: 98
effective length of query: 123
effective length of database: 14,536,650
effective search space: 1788007950
effective search space used: 1788007950
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.