Search of human proteins with 89060961

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|89060961 PREDICTED: FERM and PDZ domain containing 3 [Homo
sapiens]
         (1810 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|89060961 PREDICTED: FERM and PDZ domain containing 3 [Homo sa...  3566   0.0  
gi|89059963 PREDICTED: FERM and PDZ domain containing 3 [Homo sa...  3566   0.0  
gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo s...  3099   0.0  
gi|211971072 FERM and PDZ domain containing 4 [Homo sapiens]          511   e-144
gi|239582741 FERM and PDZ domain containing 1 [Homo sapiens]          347   6e-95
gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens]    72   6e-12
gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens]    72   6e-12
gi|27886590 PTK2B protein tyrosine kinase 2 beta isoform a [Homo...    69   5e-11
gi|27886588 PTK2B protein tyrosine kinase 2 beta isoform b [Homo...    69   5e-11
gi|27886586 PTK2B protein tyrosine kinase 2 beta isoform a [Homo...    69   5e-11
gi|27886584 PTK2B protein tyrosine kinase 2 beta isoform a [Homo...    69   5e-11
gi|4507379 TATA box binding protein [Homo sapiens]                     64   1e-09
gi|40354197 THAP domain containing 11 [Homo sapiens]                   64   2e-09
gi|17017963 forkhead box P2 isoform I [Homo sapiens]                   63   3e-09
gi|22538413 forkhead box P2 isoform III [Homo sapiens]                 63   3e-09
gi|149999352 forkhead box P2 isoform II [Homo sapiens]                 63   3e-09
gi|110347429 mediator complex subunit 12 [Homo sapiens]                62   7e-09
gi|33286444 mastermind-like 2 [Homo sapiens]                           61   1e-08
gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens]    60   1e-08
gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens]    60   2e-08
gi|55956910 meningioma  1 [Homo sapiens]                               60   3e-08
gi|189491748 ataxin 1 [Homo sapiens]                                   59   3e-08
gi|51479158 ataxin 1 [Homo sapiens]                                    59   3e-08
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        59   3e-08
gi|226442791 runt-related transcription factor 2 isoform b [Homo...    59   4e-08
gi|226442783 runt-related transcription factor 2 isoform a [Homo...    59   4e-08
gi|66934969 runt-related transcription factor 2 isoform c [Homo ...    59   4e-08
gi|51702521 POU domain, class 3, transcription factor 2 [Homo sa...    59   6e-08
gi|56549696 E1A binding protein p400 [Homo sapiens]                    59   6e-08
gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens]            58   7e-08

>gi|89060961 PREDICTED: FERM and PDZ domain containing 3 [Homo
            sapiens]
          Length = 1810

 Score = 3566 bits (9248), Expect = 0.0
 Identities = 1810/1810 (100%), Positives = 1810/1810 (100%)

Query: 1    METLDSQRVQDRLLAAPGCSSPSGQQELFSSHVMQEESANDMECEQLPAEILRQVTVHRD 60
            METLDSQRVQDRLLAAPGCSSPSGQQELFSSHVMQEESANDMECEQLPAEILRQVTVHRD
Sbjct: 1    METLDSQRVQDRLLAAPGCSSPSGQQELFSSHVMQEESANDMECEQLPAEILRQVTVHRD 60

Query: 61   PIYGFGFVAGSERPVVVRSVRPGGPSENKLLAGDQIVAINEEDVSEAPRERLIELIRSAK 120
            PIYGFGFVAGSERPVVVRSVRPGGPSENKLLAGDQIVAINEEDVSEAPRERLIELIRSAK
Sbjct: 61   PIYGFGFVAGSERPVVVRSVRPGGPSENKLLAGDQIVAINEEDVSEAPRERLIELIRSAK 120

Query: 121  EFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVKVRFSEQVAVGETDAKMMKKEALLLIPN 180
            EFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVKVRFSEQVAVGETDAKMMKKEALLLIPN
Sbjct: 121  EFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVKVRFSEQVAVGETDAKMMKKEALLLIPN 180

Query: 181  VLKVFLENGQIKSFTFDGRTTVKDVMLTLQDRLSLRFIEHFALVLEYAGPEQNHKFLLLQ 240
            VLKVFLENGQIKSFTFDGRTTVKDVMLTLQDRLSLRFIEHFALVLEYAGPEQNHKFLLLQ
Sbjct: 181  VLKVFLENGQIKSFTFDGRTTVKDVMLTLQDRLSLRFIEHFALVLEYAGPEQNHKFLLLQ 240

Query: 241  DKQPLAYVVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRNDVIRERFGMD 300
            DKQPLAYVVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRNDVIRERFGMD
Sbjct: 241  DKQPLAYVVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRNDVIRERFGMD 300

Query: 301  PKPEMLLGLAALHIYITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQVIKEKNLRKSLS 360
            PKPEMLLGLAALHIYITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQVIKEKNLRKSLS
Sbjct: 301  PKPEMLLGLAALHIYITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQVIKEKNLRKSLS 360

Query: 361  QQLKAHQTHPSCGTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKQSATTLLVGPRH 420
            QQLKAHQTHPSCGTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKQSATTLLVGPRH
Sbjct: 361  QQLKAHQTHPSCGTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKQSATTLLVGPRH 420

Query: 421  GISHVIDLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDAKPLVLLMEWPEATNFA 480
            GISHVIDLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDAKPLVLLMEWPEATNFA
Sbjct: 421  GISHVIDLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDAKPLVLLMEWPEATNFA 480

Query: 481  CLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKADYMHSAHRPVTGGHLGKKESSYVGSVG 540
            CLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKADYMHSAHRPVTGGHLGKKESSYVGSVG
Sbjct: 481  CLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKADYMHSAHRPVTGGHLGKKESSYVGSVG 540

Query: 541  TSPRKSSRCTPPPADSELVSFCYLHMREQRKEQESRTDVNENLIFFEETRPRTKSDPTSK 600
            TSPRKSSRCTPPPADSELVSFCYLHMREQRKEQESRTDVNENLIFFEETRPRTKSDPTSK
Sbjct: 541  TSPRKSSRCTPPPADSELVSFCYLHMREQRKEQESRTDVNENLIFFEETRPRTKSDPTSK 600

Query: 601  SSGQGYEVVPDDFDAASLDHEPCASRARSYTLDNSLGAEALNFYCDSCKAKLQEQLGPRK 660
            SSGQGYEVVPDDFDAASLDHEPCASRARSYTLDNSLGAEALNFYCDSCKAKLQEQLGPRK
Sbjct: 601  SSGQGYEVVPDDFDAASLDHEPCASRARSYTLDNSLGAEALNFYCDSCKAKLQEQLGPRK 660

Query: 661  GGKPGSSRDNIVDLMSLPPPGSEEEEEEEDETTSLLPAIAAPPPGFRDNSSDEDDPKRRA 720
            GGKPGSSRDNIVDLMSLPPPGSEEEEEEEDETTSLLPAIAAPPPGFRDNSSDEDDPKRRA
Sbjct: 661  GGKPGSSRDNIVDLMSLPPPGSEEEEEEEDETTSLLPAIAAPPPGFRDNSSDEDDPKRRA 720

Query: 721  VQSQEQGRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPH 780
            VQSQEQGRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPH
Sbjct: 721  VQSQEQGRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPH 780

Query: 781  PPPPQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKDS 840
            PPPPQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKDS
Sbjct: 781  PPPPQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKDS 840

Query: 841  LLARKDLPFRIQSCAAQAVLTAPYSLGRPDPNPSLQPIATGQSPGPPGARRKLPQSEGQV 900
            LLARKDLPFRIQSCAAQAVLTAPYSLGRPDPNPSLQPIATGQSPGPPGARRKLPQSEGQV
Sbjct: 841  LLARKDLPFRIQSCAAQAVLTAPYSLGRPDPNPSLQPIATGQSPGPPGARRKLPQSEGQV 900

Query: 901  QGERTYSLAVHPALSPQLSEQKNLSLLSPVPEDKGPGHTRAGLEMSLRAATSSLSEEQVS 960
            QGERTYSLAVHPALSPQLSEQKNLSLLSPVPEDKGPGHTRAGLEMSLRAATSSLSEEQVS
Sbjct: 901  QGERTYSLAVHPALSPQLSEQKNLSLLSPVPEDKGPGHTRAGLEMSLRAATSSLSEEQVS 960

Query: 961  ELRDNLPKEVRLSPKLILDPKSSVTPAIISAALQQVVHNKSLVTAGGALGNPPSRGERRL 1020
            ELRDNLPKEVRLSPKLILDPKSSVTPAIISAALQQVVHNKSLVTAGGALGNPPSRGERRL
Sbjct: 961  ELRDNLPKEVRLSPKLILDPKSSVTPAIISAALQQVVHNKSLVTAGGALGNPPSRGERRL 1020

Query: 1021 EASMGRPEVSMMSSSASKNLKFKISPSAPETSWNSQHQLGAEVSSSPRAPTGSRADSLHL 1080
            EASMGRPEVSMMSSSASKNLKFKISPSAPETSWNSQHQLGAEVSSSPRAPTGSRADSLHL
Sbjct: 1021 EASMGRPEVSMMSSSASKNLKFKISPSAPETSWNSQHQLGAEVSSSPRAPTGSRADSLHL 1080

Query: 1081 SQQEDSLPVQNFPPKSYLLRTSRESVGKQATGEVAGKGGPVGGKPTLQKQGTISSQGEKA 1140
            SQQEDSLPVQNFPPKSYLLRTSRESVGKQATGEVAGKGGPVGGKPTLQKQGTISSQGEKA
Sbjct: 1081 SQQEDSLPVQNFPPKSYLLRTSRESVGKQATGEVAGKGGPVGGKPTLQKQGTISSQGEKA 1140

Query: 1141 QLESTPKRSKLEETSLVPRATYPMALQSPSCQSRSHSPSCQPHGHSPSSQSRGQSPSCQP 1200
            QLESTPKRSKLEETSLVPRATYPMALQSPSCQSRSHSPSCQPHGHSPSSQSRGQSPSCQP
Sbjct: 1141 QLESTPKRSKLEETSLVPRATYPMALQSPSCQSRSHSPSCQPHGHSPSSQSRGQSPSCQP 1200

Query: 1201 RGQSPLRSQAASRQVSTMPSRKLETTLNGAHSTSEGPAKPKSSRGPFRLRNLFSATFPTR 1260
            RGQSPLRSQAASRQVSTMPSRKLETTLNGAHSTSEGPAKPKSSRGPFRLRNLFSATFPTR
Sbjct: 1201 RGQSPLRSQAASRQVSTMPSRKLETTLNGAHSTSEGPAKPKSSRGPFRLRNLFSATFPTR 1260

Query: 1261 QKKETDERQAQLQKVKQYELEFLEELLKPPSQGELPGTEYLQPPAPGRCSCQLRSSPVQQ 1320
            QKKETDERQAQLQKVKQYELEFLEELLKPPSQGELPGTEYLQPPAPGRCSCQLRSSPVQQ
Sbjct: 1261 QKKETDERQAQLQKVKQYELEFLEELLKPPSQGELPGTEYLQPPAPGRCSCQLRSSPVQQ 1320

Query: 1321 GPGMSREQRRSCDCKRICRGGRPQATQTPVPSLRGRERDRVLPSQRQPEAGPGVSLSSPI 1380
            GPGMSREQRRSCDCKRICRGGRPQATQTPVPSLRGRERDRVLPSQRQPEAGPGVSLSSPI
Sbjct: 1321 GPGMSREQRRSCDCKRICRGGRPQATQTPVPSLRGRERDRVLPSQRQPEAGPGVSLSSPI 1380

Query: 1381 NVQRIRSTSLESRECRSDPESGVSCLTTCASGGECLGAPNYRKLMRRYSISELDQGDRAS 1440
            NVQRIRSTSLESRECRSDPESGVSCLTTCASGGECLGAPNYRKLMRRYSISELDQGDRAS
Sbjct: 1381 NVQRIRSTSLESRECRSDPESGVSCLTTCASGGECLGAPNYRKLMRRYSISELDQGDRAS 1440

Query: 1441 LTSDVYPHPPLGMLPREAKEVEASLPIALGPKSRSLESPTLGDPSYVQVAPETKGPRQMA 1500
            LTSDVYPHPPLGMLPREAKEVEASLPIALGPKSRSLESPTLGDPSYVQVAPETKGPRQMA
Sbjct: 1441 LTSDVYPHPPLGMLPREAKEVEASLPIALGPKSRSLESPTLGDPSYVQVAPETKGPRQMA 1500

Query: 1501 VFSLPEEVYRKPAELDEDSESSKCCSIRYCFYYRKCDMADDASDGKDELSYSIPMKILPG 1560
            VFSLPEEVYRKPAELDEDSESSKCCSIRYCFYYRKCDMADDASDGKDELSYSIPMKILPG
Sbjct: 1501 VFSLPEEVYRKPAELDEDSESSKCCSIRYCFYYRKCDMADDASDGKDELSYSIPMKILPG 1560

Query: 1561 MKLDEQVVPVVSRTLQVLDAATCSSSSPEASRTQEIDLRVSTFEGSLAKINALRAHAYGL 1620
            MKLDEQVVPVVSRTLQVLDAATCSSSSPEASRTQEIDLRVSTFEGSLAKINALRAHAYGL
Sbjct: 1561 MKLDEQVVPVVSRTLQVLDAATCSSSSPEASRTQEIDLRVSTFEGSLAKINALRAHAYGL 1620

Query: 1621 PDGFLAARLDTNELLTVLRQCVASPEARAPKPYVSQISEYKLELALKFKELRASCRRVAN 1680
            PDGFLAARLDTNELLTVLRQCVASPEARAPKPYVSQISEYKLELALKFKELRASCRRVAN
Sbjct: 1621 PDGFLAARLDTNELLTVLRQCVASPEARAPKPYVSQISEYKLELALKFKELRASCRRVAN 1680

Query: 1681 VDKSPTHMLAAITGSFQVLSSLIETFVRLVFIVRSEAQRQELLAKVEEVVRNYTFLLRAA 1740
            VDKSPTHMLAAITGSFQVLSSLIETFVRLVFIVRSEAQRQELLAKVEEVVRNYTFLLRAA
Sbjct: 1681 VDKSPTHMLAAITGSFQVLSSLIETFVRLVFIVRSEAQRQELLAKVEEVVRNYTFLLRAA 1740

Query: 1741 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVMST 1800
            EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVMST
Sbjct: 1741 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVMST 1800

Query: 1801 FTHSLKTLIK 1810
            FTHSLKTLIK
Sbjct: 1801 FTHSLKTLIK 1810


>gi|89059963 PREDICTED: FERM and PDZ domain containing 3 [Homo
            sapiens]
          Length = 1810

 Score = 3566 bits (9248), Expect = 0.0
 Identities = 1810/1810 (100%), Positives = 1810/1810 (100%)

Query: 1    METLDSQRVQDRLLAAPGCSSPSGQQELFSSHVMQEESANDMECEQLPAEILRQVTVHRD 60
            METLDSQRVQDRLLAAPGCSSPSGQQELFSSHVMQEESANDMECEQLPAEILRQVTVHRD
Sbjct: 1    METLDSQRVQDRLLAAPGCSSPSGQQELFSSHVMQEESANDMECEQLPAEILRQVTVHRD 60

Query: 61   PIYGFGFVAGSERPVVVRSVRPGGPSENKLLAGDQIVAINEEDVSEAPRERLIELIRSAK 120
            PIYGFGFVAGSERPVVVRSVRPGGPSENKLLAGDQIVAINEEDVSEAPRERLIELIRSAK
Sbjct: 61   PIYGFGFVAGSERPVVVRSVRPGGPSENKLLAGDQIVAINEEDVSEAPRERLIELIRSAK 120

Query: 121  EFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVKVRFSEQVAVGETDAKMMKKEALLLIPN 180
            EFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVKVRFSEQVAVGETDAKMMKKEALLLIPN
Sbjct: 121  EFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVKVRFSEQVAVGETDAKMMKKEALLLIPN 180

Query: 181  VLKVFLENGQIKSFTFDGRTTVKDVMLTLQDRLSLRFIEHFALVLEYAGPEQNHKFLLLQ 240
            VLKVFLENGQIKSFTFDGRTTVKDVMLTLQDRLSLRFIEHFALVLEYAGPEQNHKFLLLQ
Sbjct: 181  VLKVFLENGQIKSFTFDGRTTVKDVMLTLQDRLSLRFIEHFALVLEYAGPEQNHKFLLLQ 240

Query: 241  DKQPLAYVVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRNDVIRERFGMD 300
            DKQPLAYVVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRNDVIRERFGMD
Sbjct: 241  DKQPLAYVVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRNDVIRERFGMD 300

Query: 301  PKPEMLLGLAALHIYITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQVIKEKNLRKSLS 360
            PKPEMLLGLAALHIYITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQVIKEKNLRKSLS
Sbjct: 301  PKPEMLLGLAALHIYITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQVIKEKNLRKSLS 360

Query: 361  QQLKAHQTHPSCGTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKQSATTLLVGPRH 420
            QQLKAHQTHPSCGTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKQSATTLLVGPRH
Sbjct: 361  QQLKAHQTHPSCGTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKQSATTLLVGPRH 420

Query: 421  GISHVIDLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDAKPLVLLMEWPEATNFA 480
            GISHVIDLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDAKPLVLLMEWPEATNFA
Sbjct: 421  GISHVIDLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDAKPLVLLMEWPEATNFA 480

Query: 481  CLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKADYMHSAHRPVTGGHLGKKESSYVGSVG 540
            CLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKADYMHSAHRPVTGGHLGKKESSYVGSVG
Sbjct: 481  CLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKADYMHSAHRPVTGGHLGKKESSYVGSVG 540

Query: 541  TSPRKSSRCTPPPADSELVSFCYLHMREQRKEQESRTDVNENLIFFEETRPRTKSDPTSK 600
            TSPRKSSRCTPPPADSELVSFCYLHMREQRKEQESRTDVNENLIFFEETRPRTKSDPTSK
Sbjct: 541  TSPRKSSRCTPPPADSELVSFCYLHMREQRKEQESRTDVNENLIFFEETRPRTKSDPTSK 600

Query: 601  SSGQGYEVVPDDFDAASLDHEPCASRARSYTLDNSLGAEALNFYCDSCKAKLQEQLGPRK 660
            SSGQGYEVVPDDFDAASLDHEPCASRARSYTLDNSLGAEALNFYCDSCKAKLQEQLGPRK
Sbjct: 601  SSGQGYEVVPDDFDAASLDHEPCASRARSYTLDNSLGAEALNFYCDSCKAKLQEQLGPRK 660

Query: 661  GGKPGSSRDNIVDLMSLPPPGSEEEEEEEDETTSLLPAIAAPPPGFRDNSSDEDDPKRRA 720
            GGKPGSSRDNIVDLMSLPPPGSEEEEEEEDETTSLLPAIAAPPPGFRDNSSDEDDPKRRA
Sbjct: 661  GGKPGSSRDNIVDLMSLPPPGSEEEEEEEDETTSLLPAIAAPPPGFRDNSSDEDDPKRRA 720

Query: 721  VQSQEQGRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPH 780
            VQSQEQGRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPH
Sbjct: 721  VQSQEQGRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPH 780

Query: 781  PPPPQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKDS 840
            PPPPQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKDS
Sbjct: 781  PPPPQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKDS 840

Query: 841  LLARKDLPFRIQSCAAQAVLTAPYSLGRPDPNPSLQPIATGQSPGPPGARRKLPQSEGQV 900
            LLARKDLPFRIQSCAAQAVLTAPYSLGRPDPNPSLQPIATGQSPGPPGARRKLPQSEGQV
Sbjct: 841  LLARKDLPFRIQSCAAQAVLTAPYSLGRPDPNPSLQPIATGQSPGPPGARRKLPQSEGQV 900

Query: 901  QGERTYSLAVHPALSPQLSEQKNLSLLSPVPEDKGPGHTRAGLEMSLRAATSSLSEEQVS 960
            QGERTYSLAVHPALSPQLSEQKNLSLLSPVPEDKGPGHTRAGLEMSLRAATSSLSEEQVS
Sbjct: 901  QGERTYSLAVHPALSPQLSEQKNLSLLSPVPEDKGPGHTRAGLEMSLRAATSSLSEEQVS 960

Query: 961  ELRDNLPKEVRLSPKLILDPKSSVTPAIISAALQQVVHNKSLVTAGGALGNPPSRGERRL 1020
            ELRDNLPKEVRLSPKLILDPKSSVTPAIISAALQQVVHNKSLVTAGGALGNPPSRGERRL
Sbjct: 961  ELRDNLPKEVRLSPKLILDPKSSVTPAIISAALQQVVHNKSLVTAGGALGNPPSRGERRL 1020

Query: 1021 EASMGRPEVSMMSSSASKNLKFKISPSAPETSWNSQHQLGAEVSSSPRAPTGSRADSLHL 1080
            EASMGRPEVSMMSSSASKNLKFKISPSAPETSWNSQHQLGAEVSSSPRAPTGSRADSLHL
Sbjct: 1021 EASMGRPEVSMMSSSASKNLKFKISPSAPETSWNSQHQLGAEVSSSPRAPTGSRADSLHL 1080

Query: 1081 SQQEDSLPVQNFPPKSYLLRTSRESVGKQATGEVAGKGGPVGGKPTLQKQGTISSQGEKA 1140
            SQQEDSLPVQNFPPKSYLLRTSRESVGKQATGEVAGKGGPVGGKPTLQKQGTISSQGEKA
Sbjct: 1081 SQQEDSLPVQNFPPKSYLLRTSRESVGKQATGEVAGKGGPVGGKPTLQKQGTISSQGEKA 1140

Query: 1141 QLESTPKRSKLEETSLVPRATYPMALQSPSCQSRSHSPSCQPHGHSPSSQSRGQSPSCQP 1200
            QLESTPKRSKLEETSLVPRATYPMALQSPSCQSRSHSPSCQPHGHSPSSQSRGQSPSCQP
Sbjct: 1141 QLESTPKRSKLEETSLVPRATYPMALQSPSCQSRSHSPSCQPHGHSPSSQSRGQSPSCQP 1200

Query: 1201 RGQSPLRSQAASRQVSTMPSRKLETTLNGAHSTSEGPAKPKSSRGPFRLRNLFSATFPTR 1260
            RGQSPLRSQAASRQVSTMPSRKLETTLNGAHSTSEGPAKPKSSRGPFRLRNLFSATFPTR
Sbjct: 1201 RGQSPLRSQAASRQVSTMPSRKLETTLNGAHSTSEGPAKPKSSRGPFRLRNLFSATFPTR 1260

Query: 1261 QKKETDERQAQLQKVKQYELEFLEELLKPPSQGELPGTEYLQPPAPGRCSCQLRSSPVQQ 1320
            QKKETDERQAQLQKVKQYELEFLEELLKPPSQGELPGTEYLQPPAPGRCSCQLRSSPVQQ
Sbjct: 1261 QKKETDERQAQLQKVKQYELEFLEELLKPPSQGELPGTEYLQPPAPGRCSCQLRSSPVQQ 1320

Query: 1321 GPGMSREQRRSCDCKRICRGGRPQATQTPVPSLRGRERDRVLPSQRQPEAGPGVSLSSPI 1380
            GPGMSREQRRSCDCKRICRGGRPQATQTPVPSLRGRERDRVLPSQRQPEAGPGVSLSSPI
Sbjct: 1321 GPGMSREQRRSCDCKRICRGGRPQATQTPVPSLRGRERDRVLPSQRQPEAGPGVSLSSPI 1380

Query: 1381 NVQRIRSTSLESRECRSDPESGVSCLTTCASGGECLGAPNYRKLMRRYSISELDQGDRAS 1440
            NVQRIRSTSLESRECRSDPESGVSCLTTCASGGECLGAPNYRKLMRRYSISELDQGDRAS
Sbjct: 1381 NVQRIRSTSLESRECRSDPESGVSCLTTCASGGECLGAPNYRKLMRRYSISELDQGDRAS 1440

Query: 1441 LTSDVYPHPPLGMLPREAKEVEASLPIALGPKSRSLESPTLGDPSYVQVAPETKGPRQMA 1500
            LTSDVYPHPPLGMLPREAKEVEASLPIALGPKSRSLESPTLGDPSYVQVAPETKGPRQMA
Sbjct: 1441 LTSDVYPHPPLGMLPREAKEVEASLPIALGPKSRSLESPTLGDPSYVQVAPETKGPRQMA 1500

Query: 1501 VFSLPEEVYRKPAELDEDSESSKCCSIRYCFYYRKCDMADDASDGKDELSYSIPMKILPG 1560
            VFSLPEEVYRKPAELDEDSESSKCCSIRYCFYYRKCDMADDASDGKDELSYSIPMKILPG
Sbjct: 1501 VFSLPEEVYRKPAELDEDSESSKCCSIRYCFYYRKCDMADDASDGKDELSYSIPMKILPG 1560

Query: 1561 MKLDEQVVPVVSRTLQVLDAATCSSSSPEASRTQEIDLRVSTFEGSLAKINALRAHAYGL 1620
            MKLDEQVVPVVSRTLQVLDAATCSSSSPEASRTQEIDLRVSTFEGSLAKINALRAHAYGL
Sbjct: 1561 MKLDEQVVPVVSRTLQVLDAATCSSSSPEASRTQEIDLRVSTFEGSLAKINALRAHAYGL 1620

Query: 1621 PDGFLAARLDTNELLTVLRQCVASPEARAPKPYVSQISEYKLELALKFKELRASCRRVAN 1680
            PDGFLAARLDTNELLTVLRQCVASPEARAPKPYVSQISEYKLELALKFKELRASCRRVAN
Sbjct: 1621 PDGFLAARLDTNELLTVLRQCVASPEARAPKPYVSQISEYKLELALKFKELRASCRRVAN 1680

Query: 1681 VDKSPTHMLAAITGSFQVLSSLIETFVRLVFIVRSEAQRQELLAKVEEVVRNYTFLLRAA 1740
            VDKSPTHMLAAITGSFQVLSSLIETFVRLVFIVRSEAQRQELLAKVEEVVRNYTFLLRAA
Sbjct: 1681 VDKSPTHMLAAITGSFQVLSSLIETFVRLVFIVRSEAQRQELLAKVEEVVRNYTFLLRAA 1740

Query: 1741 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVMST 1800
            EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVMST
Sbjct: 1741 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVMST 1800

Query: 1801 FTHSLKTLIK 1810
            FTHSLKTLIK
Sbjct: 1801 FTHSLKTLIK 1810


>gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo
            sapiens]
          Length = 1662

 Score = 3099 bits (8035), Expect = 0.0
 Identities = 1612/1777 (90%), Positives = 1628/1777 (91%), Gaps = 115/1777 (6%)

Query: 34   MQEESANDMECEQLPAEILRQVTVHRDPIYGFGFVAGSERPVVVRSVRPGGPSENKLLAG 93
            MQEESANDMECEQLPAEILRQVTVHRDPIYGFGFVAGSERPVVVRSVRPGGPSENKLLAG
Sbjct: 1    MQEESANDMECEQLPAEILRQVTVHRDPIYGFGFVAGSERPVVVRSVRPGGPSENKLLAG 60

Query: 94   DQIVAINEEDVSEAPRERLIELIRSAKEFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVK 153
            DQIVAINEEDVSEAPRERLIELIRSAKEFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVK
Sbjct: 61   DQIVAINEEDVSEAPRERLIELIRSAKEFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVK 120

Query: 154  VRFSEQVAVGETDAKMMKKEALLLIPNVLKVFLENGQIKSFTFDGRTTVKDVMLTLQDRL 213
            VRFSEQVAVGETDAKMMKKEALLLIPNVLKVFLENGQIKSFTFDGRTTVKDVMLTLQDRL
Sbjct: 121  VRFSEQVAVGETDAKMMKKEALLLIPNVLKVFLENGQIKSFTFDGRTTVKDVMLTLQDRL 180

Query: 214  SLRFIEHFALVLEYAGPEQNHKFLLLQDKQPLAYVVQRTHYHGMKCLFRISFFPKDPVEL 273
            SLRFIEHFALVLEYAGPEQNHKFLLLQDKQPLAYVVQRTHYHGMKCLFRISFFPKDPVEL
Sbjct: 181  SLRFIEHFALVLEYAGPEQNHKFLLLQDKQPLAYVVQRTHYHGMKCLFRISFFPKDPVEL 240

Query: 274  LRRDPAAFEYLYIQSRNDVIRERFGMDPKPEMLLGLAALHIYITVSATRPSQKISLKNVE 333
            LRRDPAAFEYLYIQ                                       I  KN+ 
Sbjct: 241  LRRDPAAFEYLYIQ-------------------------------XXXXXXXXIKEKNLR 269

Query: 334  KEWGLEPFLPPSLLQVIKEKNLRKSLSQQLKAHQTHPSCGTKGSAIQAKLQYLRILNELP 393
            K          SL Q +K             AHQTHPSCGTKGSAIQAKLQYLRILNELP
Sbjct: 270  K----------SLSQQLK-------------AHQTHPSCGTKGSAIQAKLQYLRILNELP 306

Query: 394  TFTGVLFNTVGLDEKQSATTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQG 453
            TFTGVLFNTVGLDEKQSATTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQG
Sbjct: 307  TFTGVLFNTVGLDEKQSATTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQG 366

Query: 454  VARVETSIMDAKPLVLLMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKA 513
            VARVETSIMDAKPLVLLMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKA
Sbjct: 367  VARVETSIMDAKPLVLLMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKA 426

Query: 514  DYMHSAHRPVTGGHLGKKESSYVGSVGTSPRKSSRCTPPPADSELVSFCYLHMREQRKEQ 573
            DYMHSAHRPVTGGHLGKKESSYVGSVGTSPRKSSRCTPPPADSELVSFCYLHMREQRKEQ
Sbjct: 427  DYMHSAHRPVTGGHLGKKESSYVGSVGTSPRKSSRCTPPPADSELVSFCYLHMREQRKEQ 486

Query: 574  ESRTDVNENLIFFEETRPRTKSDPTSKSSGQGYEVVPDDFDAASLDHEPCASRARSYTLD 633
            ESRTDVNENLIFFEETRPRTKSDPTSKSSGQGYEVVPDDFDAASLDHEPCASRARSYTLD
Sbjct: 487  ESRTDVNENLIFFEETRPRTKSDPTSKSSGQGYEVVPDDFDAASLDHEPCASRARSYTLD 546

Query: 634  NSLGAEALNFYCDSCKAKLQEQLGPRKGGKPGSSRDNIVDLMSLPPPGSEEEEEEEDETT 693
            NSLGAEALNFYCDSCKAKLQ   GP + GKPGSSRDNI+    +P               
Sbjct: 547  NSLGAEALNFYCDSCKAKLQSSXGPSQSGKPGSSRDNILLYDEIP--------------V 592

Query: 694  SLLPAIAAPPPGFRDNSSDEDDPKRRAVQSQEQGRHLRGLLYDEIPVTLIDSVQTRTVRD 753
            +L+ ++       RD++ + DD                          L+ ++Q      
Sbjct: 593  TLIDSVQTRT--VRDHAQELDD-------------------------ALVSTLQ------ 619

Query: 754  HAQELDDALVSTLQALEALAASEDGPHPPPPQTAGLIVLATITPESSLDSGHETNSSELT 813
                        L+AL   AASEDGPHPPPPQTAGLIVLATITPESSLDSGHETNSSELT
Sbjct: 620  -----------ALEAL---AASEDGPHPPPPQTAGLIVLATITPESSLDSGHETNSSELT 665

Query: 814  DMSEMMSAMKQHQNTTYFLAQHLNKDSLLARKDLPFRIQSCAAQAVLTAPYSLGRPDPNP 873
            DMSEMMSAMKQHQNTTYFLAQHLNKDSLLARKDLPFRIQSCAAQAVLTAPYSLGRPDPNP
Sbjct: 666  DMSEMMSAMKQHQNTTYFLAQHLNKDSLLARKDLPFRIQSCAAQAVLTAPYSLGRPDPNP 725

Query: 874  SLQPIATGQSPGPPGARRKLPQSEGQVQGERTYSLAVHPALSPQLSEQKNLSLLSPVPED 933
            SLQPIATGQSPGPPGARRKLPQSEGQVQGERTYSLAVHPALSPQLSEQKNLSLLSPVPED
Sbjct: 726  SLQPIATGQSPGPPGARRKLPQSEGQVQGERTYSLAVHPALSPQLSEQKNLSLLSPVPED 785

Query: 934  KGPGHTRAGLEMSLRAATSSLSEEQVSELRDNLPKEVRLSPKLILDPKSSVTPAIISAAL 993
            KGPGHTRAGLEMSLRAATSSLSEEQVSELRDNLPKEVRLSPKLILDPKSSVTPAIISAAL
Sbjct: 786  KGPGHTRAGLEMSLRAATSSLSEEQVSELRDNLPKEVRLSPKLILDPKSSVTPAIISAAL 845

Query: 994  QQVVHNKSLVTAGGALGNPPSRGERRLEASMGRPEVSMMSSSASKNLKFKISPSAPETSW 1053
            QQVVHNKSLVTAGGALGNPPSRGERRLEASMGRPEVSMMSSSASKNLKFKISPSAPETSW
Sbjct: 846  QQVVHNKSLVTAGGALGNPPSRGERRLEASMGRPEVSMMSSSASKNLKFKISPSAPETSW 905

Query: 1054 NSQHQLGAEVSSSPRAPTGSRADSLHLSQQEDSLPVQNFPPKSYLLRTSRESVGKQATGE 1113
            NSQHQLGAEVSSSPRAPTGSRADSLHLSQQEDSLPVQNFPPKSYLLRTSRESVGKQATGE
Sbjct: 906  NSQHQLGAEVSSSPRAPTGSRADSLHLSQQEDSLPVQNFPPKSYLLRTSRESVGKQATGE 965

Query: 1114 VAGKGGPVGGKPTLQKQGTISSQGEKAQLESTPKRSKLEETSLVPRATYPMALQSPSCQS 1173
            VAGKGGPVGGKPTLQKQGTISSQGEKAQLESTPKRSKLEETSLVPRATYPMALQSPSCQS
Sbjct: 966  VAGKGGPVGGKPTLQKQGTISSQGEKAQLESTPKRSKLEETSLVPRATYPMALQSPSCQS 1025

Query: 1174 RSHSPSCQPHGHSPSSQSRGQSPSCQPRGQSPLRSQAASRQVSTMPSRKLETTLNGAHST 1233
            RSHSPSCQPHGHSPSSQSRGQSPSCQPRGQSPLRSQAASRQVSTMPSRKLETTLNGAHST
Sbjct: 1026 RSHSPSCQPHGHSPSSQSRGQSPSCQPRGQSPLRSQAASRQVSTMPSRKLETTLNGAHST 1085

Query: 1234 SEGPAKPKSSRGPFRLRNLFSATFPTRQKKETDERQAQLQKVKQYELEFLEELLKPPSQG 1293
            SEGPAKPKSSRGPFRLRNLFSATFPTRQKKETDERQAQLQKVKQYELEFLEELLKPPSQG
Sbjct: 1086 SEGPAKPKSSRGPFRLRNLFSATFPTRQKKETDERQAQLQKVKQYELEFLEELLKPPSQG 1145

Query: 1294 ELPGTEYLQPPAPGRCSCQLRSSPVQQGPGMSREQRRSCDCKRICRGGRPQATQTPVPSL 1353
            ELPGTEYLQPPAPGRCSCQLRSSPVQQGPGMSREQRRSCDCKRICRGGRPQATQTPVPSL
Sbjct: 1146 ELPGTEYLQPPAPGRCSCQLRSSPVQQGPGMSREQRRSCDCKRICRGGRPQATQTPVPSL 1205

Query: 1354 RGRERDRVLPSQRQPEAGPGVSLSSPINVQRIRSTSLESRECRSDPESGVSCLTTCASGG 1413
            RGRERDRVLPSQRQPEAGPGVSLSSPINVQRIRSTSLESRECRSDPESGVSCLTTCASGG
Sbjct: 1206 RGRERDRVLPSQRQPEAGPGVSLSSPINVQRIRSTSLESRECRSDPESGVSCLTTCASGG 1265

Query: 1414 ECLGAPNYRKLMRRYSISELDQGDRASLTSDVYPHPPLGMLPREAKEVEASLPIALGPKS 1473
            ECLGAPNYRKLMRRYSISELDQGDRASLTSDVYPHPPLGMLPREAKEVEASLPIALGPKS
Sbjct: 1266 ECLGAPNYRKLMRRYSISELDQGDRASLTSDVYPHPPLGMLPREAKEVEASLPIALGPKS 1325

Query: 1474 RSLESPTLGDPSYVQVAPETKGPRQMAVFSLPEEVYRKPAELDEDSESSKCCSIRYCFYY 1533
            RSLESPTLGDPSYVQVAPETKGPRQMAVFSLPEEVYRKPAELDEDSESSKCCSIRYCFYY
Sbjct: 1326 RSLESPTLGDPSYVQVAPETKGPRQMAVFSLPEEVYRKPAELDEDSESSKCCSIRYCFYY 1385

Query: 1534 RKCDMADDASDGKDELSYSIPMKILPGMKLDEQVVPVVSRTLQVLDAATCSSSSPEASRT 1593
            RKCDMADDASDGKDELSYSIPMKILPGMKLDEQVVPVVSRTLQVLDAATCSSSSPEASRT
Sbjct: 1386 RKCDMADDASDGKDELSYSIPMKILPGMKLDEQVVPVVSRTLQVLDAATCSSSSPEASRT 1445

Query: 1594 QEIDLRVSTFEGSLAKINALRAHAYGLPDGFLAARLDTNELLTVLRQCVASPEARAPKPY 1653
            QEIDLRVSTFEGSLAKINALRAHAYGLPDGFLAARLDTNELLTVLRQCVASPEARAPKPY
Sbjct: 1446 QEIDLRVSTFEGSLAKINALRAHAYGLPDGFLAARLDTNELLTVLRQCVASPEARAPKPY 1505

Query: 1654 VSQISEYKLELALKFKELRASCRRVANVDKSPTHMLAAITGSFQVLSSLIETFVRLVFIV 1713
            VSQISEYKLELALKFKELRASCRRVANVDKSPTHMLAAITGSFQVLSSLIETFVRLVFIV
Sbjct: 1506 VSQISEYKLELALKFKELRASCRRVANVDKSPTHMLAAITGSFQVLSSLIETFVRLVFIV 1565

Query: 1714 RSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQ 1773
            RSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 1566 RSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQ 1625

Query: 1774 QQQVAAAAGAATEHPPGSPTSATVMSTFTHSLKTLIK 1810
            QQQVAAAAGAATEHPPGSPTSATVMSTFTHSLKTLIK
Sbjct: 1626 QQQVAAAAGAATEHPPGSPTSATVMSTFTHSLKTLIK 1662


>gi|211971072 FERM and PDZ domain containing 4 [Homo sapiens]
          Length = 1322

 Score =  511 bits (1317), Expect = e-144
 Identities = 265/477 (55%), Positives = 355/477 (74%), Gaps = 3/477 (0%)

Query: 26  QELFSSHVMQEESANDMECE--QLPAEILRQVTVHRDPIYGFGFVAGSERPVVVRSVRPG 83
           ++ F +H+ Q    +D   E  Q+     R+V + RDP+ GFGFVAGSE+PVVVRSV PG
Sbjct: 48  RDYFINHMTQAIPFDDPRLESCQIIPPAPRKVEMRRDPVLGFGFVAGSEKPVVVRSVTPG 107

Query: 84  GPSENKLLAGDQIVAINEEDVSEAPRERLIELIRSAKEFIVLTVLHTHQSPKSAFISAAK 143
           GPSE KL+ GDQIV IN+E VS APRER+I+L+RS KE I+LTV+  + SPKSAFISAAK
Sbjct: 108 GPSEGKLIPGDQIVMINDEPVSAAPRERVIDLVRSCKESILLTVIQPYPSPKSAFISAAK 167

Query: 144 KAKLRSNPVKVRFSEQVAVGETDAKMMKKEALLLIPNVLKVFLENGQIKSFTFDGRTTVK 203
           KA+L+SNPVKVRFSE+V +    ++ +K  +LL +PNVLKV+LENGQ KSF FD  T++K
Sbjct: 168 KARLKSNPVKVRFSEEVIINGQVSETVKDNSLLFMPNVLKVYLENGQTKSFRFDCSTSIK 227

Query: 204 DVMLTLQDRLSLRFIEHFALVLEYAGPEQNHKFLLLQDKQPLAYVVQRTHYHGMKCLFRI 263
           DV+LTLQ++LS++ IEHF+L+LE        K LLL +++ L  V QR   H M+CLFRI
Sbjct: 228 DVILTLQEKLSIKGIEHFSLMLEQRTEGAGTKLLLLHEQETLTQVTQRPSSHKMRCLFRI 287

Query: 264 SFFPKDPVELLRRDPAAFEYLYIQSRNDVIRERFGMDPKPEMLLGLAALHIYITVSATRP 323
           SF PKDP++LLRRDP AFEYLY+QS NDV++ERFG + K ++ L LAAL +YI    T+ 
Sbjct: 288 SFVPKDPIDLLRRDPVAFEYLYVQSCNDVVQERFGPELKYDIALRLAALQMYIATVTTKQ 347

Query: 324 SQKISLKNVEKEWGLEPFLPPSLLQVIKEKNLRKSLSQQLKAHQTHPSCGTKGSAIQAKL 383
           +QKISLK +EKEWGLE FLP ++LQ +KEKN++K+LS  +KA+Q     G K SA+QAK+
Sbjct: 348 TQKISLKYIEKEWGLETFLPSAVLQSMKEKNIKKALSHLVKANQNLVPPGKKLSALQAKV 407

Query: 384 QYLRILNELPTFTGVLFN-TVGLDEKQSATTLLVGPRHGISHVIDLKTNLTTVLSEFSKI 442
            YL+ L++L  + G +F  T+   EK+S  TLLVGPR+GISHVI+ KTNL  +L++FS +
Sbjct: 408 HYLKFLSDLRLYGGRVFKATLVQAEKRSEVTLLVGPRYGISHVINTKTNLVALLADFSHV 467

Query: 443 SKIQLFRENQGVARVETSIMDAKPLVLLMEWPEATNFACLIAGYCRLLLDSRKMVFS 499
           ++I++F E + + RVE  ++D KP+ LLME  +A N ACL AGY RLL+DSR+ +F+
Sbjct: 468 NRIEMFSEEESLVRVELHVLDVKPITLLMESSDAMNLACLTAGYYRLLVDSRRSIFN 524



 Score =  132 bits (332), Expect = 3e-30
 Identities = 82/170 (48%), Positives = 109/170 (64%), Gaps = 6/170 (3%)

Query: 667 SRDNIVDLMSLPPPGSEEEEEEEDETTSLLPAIAAPPPGFRDNSSDEDDPKRRAVQSQEQ 726
           S D+I+DL SLPPP  ++ E++     SL  AIAAPPPGFRD SSDE+D + +A    E 
Sbjct: 776 SSDDIIDLTSLPPPEGDDNEDDF-LLRSLNMAIAAPPPGFRD-SSDEEDSQSQAASFPED 833

Query: 727 GRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPHPPPPQT 786
                 L  DEIPV+LID+V T       + LD+A+VSTL ALEAL+ SE+         
Sbjct: 834 KEKGSSLQNDEIPVSLIDAVPTSAEGKCEKGLDNAVVSTLGALEALSVSEE---QQTSDN 890

Query: 787 AGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQN-TTYFLAQH 835
           +G+ +L   +PESS DSG+ETNSSE+T+ SE+ +A KQ +N +  FLA H
Sbjct: 891 SGVAILRAYSPESSSDSGNETNSSEMTESSELATAQKQSENLSRMFLATH 940


>gi|239582741 FERM and PDZ domain containing 1 [Homo sapiens]
          Length = 1578

 Score =  347 bits (890), Expect = 6e-95
 Identities = 191/446 (42%), Positives = 293/446 (65%), Gaps = 14/446 (3%)

Query: 65  FGFVAGSERPVVVRSVRPGGPSENKLLAGDQIVAINEEDVSEAPRERLIELIRSAKEFIV 124
           +GF      P+ V +V  GG +  KL  GDQI+ +N E   +   ER ++++R A++ + 
Sbjct: 69  YGFHISESLPLTVVAVTAGGSAHGKLFPGDQILQMNNEPAEDLSWERAVDILREAEDSLS 128

Query: 125 LTVLH-THQSPKSAFISAAKKAKLRSNPVKVRFSEQVAVGETDAKMMKKEALLLIPNVLK 183
           +TV+  T   PKS+F++  K+A+L++NPVKV F+E+V +        +  +LL +PNVLK
Sbjct: 129 ITVVRCTSGVPKSSFLTEEKRARLKTNPVKVHFAEEVLISGHS----QGNSLLCMPNVLK 184

Query: 184 VFLENGQIKSFTFDGRTTVKDVMLTLQDRLSLRFIEHFALVLEYAGPEQNH--KFLLLQD 241
           ++LENGQ K+F F+  TTVKD++LT++++LS+R IE+FAL LE    EQ    +  LL +
Sbjct: 185 LYLENGQTKAFKFEANTTVKDIILTVKEKLSIRSIEYFALALE----EQYSISRLHLLHE 240

Query: 242 KQPLAYVVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRNDVIRERFGMDP 301
           ++ +  VV+R   H  +CLFR+ F PKDP++LL+ DP AFEYLY+QS +DV++ERF ++ 
Sbjct: 241 EELIQQVVEREESHDYRCLFRVCFVPKDPLDLLKEDPVAFEYLYLQSCSDVLQERFAVEM 300

Query: 302 KPEMLLGLAALHIYITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQVIKEKNLRKSLSQ 361
           K    L LAALHI   + A    QKISLK +EK+WG+E F+ P+LL+ +K K+++K++S 
Sbjct: 301 KCSSALRLAALHIQERIYACAQPQKISLKYIEKDWGIENFISPTLLRNMKGKDIKKAISF 360

Query: 362 QLKAHQT--HPSCGTKGSAIQAKLQYLRILNELPTFTGVLFN-TVGLDEKQSATTLLVGP 418
            +K +Q    P      SA Q +L YL+IL EL T+ G +FN T+ L +++S   LLVG 
Sbjct: 361 HMKRNQNLLEPRQKQLISAAQLRLNYLQILGELKTYGGRIFNATLMLQDRESYIALLVGA 420

Query: 419 RHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDAKPLVLLMEWPEATN 478
           ++GIS VI+ K N+ + L+EF+ IS+++L  E++ V+ V+  + D K L LL+E   A +
Sbjct: 421 KYGISQVINSKLNIMSTLAEFANISRVELTEESEKVSVVKVYLQDVKVLTLLLESNSAKD 480

Query: 479 FACLIAGYCRLLLDSRKMVFSRPASQ 504
            ACLIAGY RLL+D    +F  P ++
Sbjct: 481 LACLIAGYYRLLVDPVTSIFLWPGNK 506



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 34/137 (24%), Positives = 58/137 (42%)

Query: 1610 INALRAHAYGLPDGFLAARLDTNELLTVLRQCVASPEARAPKPYVSQISEYKLELALKFK 1669
            +  L+A     P+GF+       EL  +L           P+      +E +  L +  +
Sbjct: 1408 LRQLKATPASTPEGFIQLMESLLELQDILETSWGVGNKHPPEKCTWHFTESRSRLCMGSQ 1467

Query: 1670 ELRASCRRVANVDKSPTHMLAAITGSFQVLSSLIETFVRLVFIVRSEAQRQELLAKVEEV 1729
            +L +SCR V  +D+SP  M  A+  +FQ L  L     +     R  A+ +E    + +V
Sbjct: 1468 KLLSSCRHVIRMDQSPEEMQGAVRDTFQHLVQLAGLCFQFTDCSRCSARHREAAGNLRDV 1527

Query: 1730 VRNYTFLLRAAEESTAR 1746
            V  Y   + AA+ +  R
Sbjct: 1528 VYTYHQFIEAAKSTCER 1544


>gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens]
          Length = 1074

 Score = 71.6 bits (174), Expect = 6e-12
 Identities = 73/318 (22%), Positives = 134/318 (42%), Gaps = 27/318 (8%)

Query: 200 TTVKDVMLTLQDRLSLRFIEHFALVLEYAGPEQNHKFLL------LQDKQPLAYVVQRTH 253
           T V+ ++  + D   ++ +  +   L +   E+ H   +      +++K  LA+  +   
Sbjct: 84  TDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEWK 143

Query: 254 YHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRNDVIRERFGMDPKPEMLLGLAALH 313
           Y       RI + PK  +     D     + Y Q ++D + E        E+ L L  L 
Sbjct: 144 YE-----LRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLE-IADQVDQEIALKLGCLE 197

Query: 314 I---YITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQVIKEKNLRKSLSQQLKAHQTHP 370
           I   Y  +      +K + + +EK+ GL+ F P SLL  +K K LRK + Q  +      
Sbjct: 198 IRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQF---- 253

Query: 371 SCGTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKQSATTLLVGPRHGISHVIDLKT 430
                 +  ++ L++  IL+ +  F    F          +  L +GP  GIS++ D   
Sbjct: 254 ---ANLNREESILKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGC 310

Query: 431 NLTTVLSEFSKISKIQLF----RENQGVARVETSIMDAKPLVLLMEWPEATNFACLIAGY 486
           N  T L++F+++  IQ      ++ +G+ +++ +       V       A N A LI GY
Sbjct: 311 N-PTHLADFTQVQTIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGY 369

Query: 487 CRLLLDSRKMVFSRPASQ 504
           CRL+  + +    RP  +
Sbjct: 370 CRLVNGTSQSFIIRPQKE 387


>gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens]
          Length = 1052

 Score = 71.6 bits (174), Expect = 6e-12
 Identities = 73/318 (22%), Positives = 134/318 (42%), Gaps = 27/318 (8%)

Query: 200 TTVKDVMLTLQDRLSLRFIEHFALVLEYAGPEQNHKFLL------LQDKQPLAYVVQRTH 253
           T V+ ++  + D   ++ +  +   L +   E+ H   +      +++K  LA+  +   
Sbjct: 62  TDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEWK 121

Query: 254 YHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRNDVIRERFGMDPKPEMLLGLAALH 313
           Y       RI + PK  +     D     + Y Q ++D + E        E+ L L  L 
Sbjct: 122 YE-----LRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLE-IADQVDQEIALKLGCLE 175

Query: 314 I---YITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQVIKEKNLRKSLSQQLKAHQTHP 370
           I   Y  +      +K + + +EK+ GL+ F P SLL  +K K LRK + Q  +      
Sbjct: 176 IRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQF---- 231

Query: 371 SCGTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKQSATTLLVGPRHGISHVIDLKT 430
                 +  ++ L++  IL+ +  F    F          +  L +GP  GIS++ D   
Sbjct: 232 ---ANLNREESILKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGC 288

Query: 431 NLTTVLSEFSKISKIQLF----RENQGVARVETSIMDAKPLVLLMEWPEATNFACLIAGY 486
           N  T L++F+++  IQ      ++ +G+ +++ +       V       A N A LI GY
Sbjct: 289 N-PTHLADFTQVQTIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGY 347

Query: 487 CRLLLDSRKMVFSRPASQ 504
           CRL+  + +    RP  +
Sbjct: 348 CRLVNGTSQSFIIRPQKE 365


>gi|27886590 PTK2B protein tyrosine kinase 2 beta isoform a [Homo
           sapiens]
          Length = 1009

 Score = 68.6 bits (166), Expect = 5e-11
 Identities = 73/305 (23%), Positives = 130/305 (42%), Gaps = 32/305 (10%)

Query: 199 RTTVKDVMLTLQDRLSLRFIEHFALVLEYAGPEQNHKFLL------LQDKQPLAYVVQRT 252
           R  +  ++L+ +   ++R  E + L L++   ++ H          +QDK    +V    
Sbjct: 68  REIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYECLHVEAEW 127

Query: 253 HYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRNDVIRERFGMDPKPEMLLGLAAL 312
            Y       +I + P+D +E L+ D     Y Y Q RND + +R+       M L L  L
Sbjct: 128 RYD-----LQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYM-QRYASKVSEGMALQLGCL 181

Query: 313 HI---YITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQVIKEKNLRKSLSQQLKAHQTH 369
            +   +  +      +K + + +EKE GL+ F P  + + +K K  RK + Q  + +   
Sbjct: 182 ELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQY--- 238

Query: 370 PSCGTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKQS---ATTLLVGPRHGISHVI 426
                  ++++ +   ++  N L  F  +   T   +  Q       L++GP+ GI  + 
Sbjct: 239 -------ASLREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPK-GIRQLT 290

Query: 427 DLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDAKPLVLL--MEWPEATNFACLIA 484
                  T L+EF +I  I+     +G A ++  I  A   + +      EA N A LI 
Sbjct: 291 SQDAK-PTCLAEFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLID 349

Query: 485 GYCRL 489
           GYCRL
Sbjct: 350 GYCRL 354


>gi|27886588 PTK2B protein tyrosine kinase 2 beta isoform b [Homo
           sapiens]
          Length = 967

 Score = 68.6 bits (166), Expect = 5e-11
 Identities = 73/305 (23%), Positives = 130/305 (42%), Gaps = 32/305 (10%)

Query: 199 RTTVKDVMLTLQDRLSLRFIEHFALVLEYAGPEQNHKFLL------LQDKQPLAYVVQRT 252
           R  +  ++L+ +   ++R  E + L L++   ++ H          +QDK    +V    
Sbjct: 68  REIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYECLHVEAEW 127

Query: 253 HYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRNDVIRERFGMDPKPEMLLGLAAL 312
            Y       +I + P+D +E L+ D     Y Y Q RND + +R+       M L L  L
Sbjct: 128 RYD-----LQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYM-QRYASKVSEGMALQLGCL 181

Query: 313 HI---YITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQVIKEKNLRKSLSQQLKAHQTH 369
            +   +  +      +K + + +EKE GL+ F P  + + +K K  RK + Q  + +   
Sbjct: 182 ELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQY--- 238

Query: 370 PSCGTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKQS---ATTLLVGPRHGISHVI 426
                  ++++ +   ++  N L  F  +   T   +  Q       L++GP+ GI  + 
Sbjct: 239 -------ASLREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPK-GIRQLT 290

Query: 427 DLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDAKPLVLL--MEWPEATNFACLIA 484
                  T L+EF +I  I+     +G A ++  I  A   + +      EA N A LI 
Sbjct: 291 SQDAK-PTCLAEFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLID 349

Query: 485 GYCRL 489
           GYCRL
Sbjct: 350 GYCRL 354


>gi|27886586 PTK2B protein tyrosine kinase 2 beta isoform a [Homo
           sapiens]
          Length = 1009

 Score = 68.6 bits (166), Expect = 5e-11
 Identities = 73/305 (23%), Positives = 130/305 (42%), Gaps = 32/305 (10%)

Query: 199 RTTVKDVMLTLQDRLSLRFIEHFALVLEYAGPEQNHKFLL------LQDKQPLAYVVQRT 252
           R  +  ++L+ +   ++R  E + L L++   ++ H          +QDK    +V    
Sbjct: 68  REIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYECLHVEAEW 127

Query: 253 HYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRNDVIRERFGMDPKPEMLLGLAAL 312
            Y       +I + P+D +E L+ D     Y Y Q RND + +R+       M L L  L
Sbjct: 128 RYD-----LQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYM-QRYASKVSEGMALQLGCL 181

Query: 313 HI---YITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQVIKEKNLRKSLSQQLKAHQTH 369
            +   +  +      +K + + +EKE GL+ F P  + + +K K  RK + Q  + +   
Sbjct: 182 ELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQY--- 238

Query: 370 PSCGTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKQS---ATTLLVGPRHGISHVI 426
                  ++++ +   ++  N L  F  +   T   +  Q       L++GP+ GI  + 
Sbjct: 239 -------ASLREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPK-GIRQLT 290

Query: 427 DLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDAKPLVLL--MEWPEATNFACLIA 484
                  T L+EF +I  I+     +G A ++  I  A   + +      EA N A LI 
Sbjct: 291 SQDAK-PTCLAEFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLID 349

Query: 485 GYCRL 489
           GYCRL
Sbjct: 350 GYCRL 354


>gi|27886584 PTK2B protein tyrosine kinase 2 beta isoform a [Homo
           sapiens]
          Length = 1009

 Score = 68.6 bits (166), Expect = 5e-11
 Identities = 73/305 (23%), Positives = 130/305 (42%), Gaps = 32/305 (10%)

Query: 199 RTTVKDVMLTLQDRLSLRFIEHFALVLEYAGPEQNHKFLL------LQDKQPLAYVVQRT 252
           R  +  ++L+ +   ++R  E + L L++   ++ H          +QDK    +V    
Sbjct: 68  REIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYECLHVEAEW 127

Query: 253 HYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRNDVIRERFGMDPKPEMLLGLAAL 312
            Y       +I + P+D +E L+ D     Y Y Q RND + +R+       M L L  L
Sbjct: 128 RYD-----LQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYM-QRYASKVSEGMALQLGCL 181

Query: 313 HI---YITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQVIKEKNLRKSLSQQLKAHQTH 369
            +   +  +      +K + + +EKE GL+ F P  + + +K K  RK + Q  + +   
Sbjct: 182 ELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQY--- 238

Query: 370 PSCGTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKQS---ATTLLVGPRHGISHVI 426
                  ++++ +   ++  N L  F  +   T   +  Q       L++GP+ GI  + 
Sbjct: 239 -------ASLREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPK-GIRQLT 290

Query: 427 DLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDAKPLVLL--MEWPEATNFACLIA 484
                  T L+EF +I  I+     +G A ++  I  A   + +      EA N A LI 
Sbjct: 291 SQDAK-PTCLAEFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLID 349

Query: 485 GYCRL 489
           GYCRL
Sbjct: 350 GYCRL 354


>gi|4507379 TATA box binding protein [Homo sapiens]
          Length = 339

 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 33/56 (58%), Positives = 37/56 (66%)

Query: 1741 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSAT 1796
            ++   +   QQQQQQQQQQQQQQQQQQQQQQQQQQQ A AA A  +      T  T
Sbjct: 59   QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGT 114



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 31/44 (70%), Positives = 34/44 (77%)

Query: 1738 RAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAA 1781
            R  ++   +   QQQQQQQQQQQQQQQQQQQQQQQQQQQ  AAA
Sbjct: 57   RQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAA 100



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 31/46 (67%), Positives = 35/46 (76%)

Query: 1741 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATE 1786
            ++   +   QQQQQQQQQQQQQQQQQQQQQQQQQQQ  A A AA +
Sbjct: 58   QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQ 103



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 34/65 (52%), Positives = 38/65 (58%)

Query: 1732 NYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGS 1791
            N   +L   +    +   QQQQQQQQQQQQQQQQQQQQQQQQQQQ    A AA      +
Sbjct: 47   NSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQST 106

Query: 1792 PTSAT 1796
               AT
Sbjct: 107  SQQAT 111



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 32/61 (52%), Positives = 36/61 (59%)

Query: 1741 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVMST 1800
            ++   +   QQQQQQQQQQQQQQQQQQQQQQQQQ   AAA   +T       TS      
Sbjct: 62   QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQL 121

Query: 1801 F 1801
            F
Sbjct: 122  F 122



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 30/77 (38%), Positives = 38/77 (49%), Gaps = 8/77 (10%)

Query: 1718 QRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQ--------Q 1769
            Q    L+ +EE  R      +  ++   +   QQQQQQQQQQQQQQQQQQQ        Q
Sbjct: 44   QNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQ 103

Query: 1770 QQQQQQQVAAAAGAATE 1786
            Q   QQ     +G A +
Sbjct: 104  QSTSQQATQGTSGQAPQ 120


>gi|40354197 THAP domain containing 11 [Homo sapiens]
          Length = 314

 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 39/67 (58%), Positives = 42/67 (62%), Gaps = 4/67 (5%)

Query: 1738 RAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQ----VAAAAGAATEHPPGSPT 1793
            R A  + AR   QQQQQQQQQQQQQQQQQQQQQQQQQQQ     A+ A  A   P     
Sbjct: 93   RPAGAAAARRRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSPSASTAQTAQLQPNLVSA 152

Query: 1794 SATVMST 1800
            SA V+ T
Sbjct: 153  SAAVLLT 159



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 25/56 (44%), Positives = 31/56 (55%)

Query: 1741 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSAT 1796
            E   AR        +++QQQQQQQQQQQQQQQQQQQ         +  P + T+ T
Sbjct: 87   ERKVARRPAGAAAARRRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSPSASTAQT 142



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 22/42 (52%), Positives = 25/42 (59%)

Query: 1735 FLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1776
            F LR   E             +++QQQQQQQQQQQQQQQQQQ
Sbjct: 80   FPLRGVNERKVARRPAGAAAARRRQQQQQQQQQQQQQQQQQQ 121


>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
          Length = 715

 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 34/65 (52%), Positives = 44/65 (67%), Gaps = 2/65 (3%)

Query: 1712 IVRSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQ 1771
            ++  + Q QE   K +E +  +  LL+  ++   +   QQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 128  VMLQQQQLQEFYKKQQEQL--HLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 185

Query: 1772 QQQQQ 1776
            QQQQQ
Sbjct: 186  QQQQQ 190



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 29/39 (74%), Positives = 30/39 (76%)

Query: 1750 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHP 1788
            QQQQQQQQQQQQQQQQQQQQQQQQQQQ         +HP
Sbjct: 155  QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHP 193



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 29/41 (70%), Positives = 30/41 (73%)

Query: 1750 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPG 1790
            QQQQQQQQQQQQQQQQQQQQQQQQQQQ         +  PG
Sbjct: 154  QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPG 194



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 33/64 (51%), Positives = 39/64 (60%), Gaps = 1/64 (1%)

Query: 1713 VRSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQ 1772
            V S  Q Q LL + + V+      L+   +     L+ Q  QQQQQQQQQQQQQQQQQQQ
Sbjct: 112  VLSPQQLQALLQQQQAVMLQQQ-QLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQ 170

Query: 1773 QQQQ 1776
            QQQQ
Sbjct: 171  QQQQ 174



 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 29/52 (55%), Positives = 33/52 (63%), Gaps = 13/52 (25%)

Query: 1741 EESTARNLNQQQQQQQQQQQQQQQQQ-------------QQQQQQQQQQVAA 1779
            ++   +   QQQQQQQQQQQQQQQQQ             QQQQQQQQQQ+AA
Sbjct: 161  QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 212



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 22/40 (55%), Positives = 28/40 (70%)

Query: 1741 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAA 1780
            ++   +   QQQQQQQQQQ   +Q ++QQQQQQQQQ  AA
Sbjct: 173  QQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 212



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 24/45 (53%), Positives = 28/45 (62%), Gaps = 8/45 (17%)

Query: 1741 EESTARNLNQQQQQQQQQQQQ--------QQQQQQQQQQQQQQQV 1777
            ++   +   QQQQQQQQQQQQ        QQQQQQQQQQ   QQ+
Sbjct: 171  QQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 215



 Score = 35.0 bits (79), Expect = 0.66
 Identities = 23/60 (38%), Positives = 35/60 (58%), Gaps = 3/60 (5%)

Query: 1720 QELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQ---QQQQQQQQQQQQQ 1776
            Q++   +++ V +   L    ++  A  L QQQ Q+  ++QQ+Q   Q  QQQQQQQQQQ
Sbjct: 102  QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 161



 Score = 33.5 bits (75), Expect = 1.9
 Identities = 20/32 (62%), Positives = 20/32 (62%), Gaps = 8/32 (25%)

Query: 1750 QQQQQQQQQQ--------QQQQQQQQQQQQQQ 1773
            QQQQQQQQQQ        QQQ  Q QQ QQQQ
Sbjct: 200  QQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQ 231


>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
          Length = 623

 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 34/65 (52%), Positives = 44/65 (67%), Gaps = 2/65 (3%)

Query: 1712 IVRSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQ 1771
            ++  + Q QE   K +E +  +  LL+  ++   +   QQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 36   VMLQQQQLQEFYKKQQEQL--HLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 93

Query: 1772 QQQQQ 1776
            QQQQQ
Sbjct: 94   QQQQQ 98



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 29/39 (74%), Positives = 30/39 (76%)

Query: 1750 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHP 1788
            QQQQQQQQQQQQQQQQQQQQQQQQQQQ         +HP
Sbjct: 63   QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHP 101



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 29/41 (70%), Positives = 30/41 (73%)

Query: 1750 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPG 1790
            QQQQQQQQQQQQQQQQQQQQQQQQQQQ         +  PG
Sbjct: 62   QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPG 102



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 33/64 (51%), Positives = 39/64 (60%), Gaps = 1/64 (1%)

Query: 1713 VRSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQ 1772
            V S  Q Q LL + + V+      L+   +     L+ Q  QQQQQQQQQQQQQQQQQQQ
Sbjct: 20   VLSPQQLQALLQQQQAVMLQQQ-QLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQ 78

Query: 1773 QQQQ 1776
            QQQQ
Sbjct: 79   QQQQ 82



 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 29/52 (55%), Positives = 33/52 (63%), Gaps = 13/52 (25%)

Query: 1741 EESTARNLNQQQQQQQQQQQQQQQQQ-------------QQQQQQQQQQVAA 1779
            ++   +   QQQQQQQQQQQQQQQQQ             QQQQQQQQQQ+AA
Sbjct: 69   QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 120



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 22/40 (55%), Positives = 28/40 (70%)

Query: 1741 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAA 1780
            ++   +   QQQQQQQQQQ   +Q ++QQQQQQQQQ  AA
Sbjct: 81   QQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 120



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 24/45 (53%), Positives = 28/45 (62%), Gaps = 8/45 (17%)

Query: 1741 EESTARNLNQQQQQQQQQQQQ--------QQQQQQQQQQQQQQQV 1777
            ++   +   QQQQQQQQQQQQ        QQQQQQQQQQ   QQ+
Sbjct: 79   QQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 123



 Score = 35.0 bits (79), Expect = 0.66
 Identities = 23/60 (38%), Positives = 35/60 (58%), Gaps = 3/60 (5%)

Query: 1720 QELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQ---QQQQQQQQQQQQQ 1776
            Q++   +++ V +   L    ++  A  L QQQ Q+  ++QQ+Q   Q  QQQQQQQQQQ
Sbjct: 10   QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 69



 Score = 33.5 bits (75), Expect = 1.9
 Identities = 20/32 (62%), Positives = 20/32 (62%), Gaps = 8/32 (25%)

Query: 1750 QQQQQQQQQQ--------QQQQQQQQQQQQQQ 1773
            QQQQQQQQQQ        QQQ  Q QQ QQQQ
Sbjct: 108  QQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQ 139


>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
          Length = 740

 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 34/65 (52%), Positives = 44/65 (67%), Gaps = 2/65 (3%)

Query: 1712 IVRSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQ 1771
            ++  + Q QE   K +E +  +  LL+  ++   +   QQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 153  VMLQQQQLQEFYKKQQEQL--HLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 210

Query: 1772 QQQQQ 1776
            QQQQQ
Sbjct: 211  QQQQQ 215



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 29/39 (74%), Positives = 30/39 (76%)

Query: 1750 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHP 1788
            QQQQQQQQQQQQQQQQQQQQQQQQQQQ         +HP
Sbjct: 180  QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHP 218



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 29/41 (70%), Positives = 30/41 (73%)

Query: 1750 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPG 1790
            QQQQQQQQQQQQQQQQQQQQQQQQQQQ         +  PG
Sbjct: 179  QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPG 219



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 33/64 (51%), Positives = 39/64 (60%), Gaps = 1/64 (1%)

Query: 1713 VRSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQ 1772
            V S  Q Q LL + + V+      L+   +     L+ Q  QQQQQQQQQQQQQQQQQQQ
Sbjct: 137  VLSPQQLQALLQQQQAVMLQQQ-QLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQ 195

Query: 1773 QQQQ 1776
            QQQQ
Sbjct: 196  QQQQ 199



 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 29/52 (55%), Positives = 33/52 (63%), Gaps = 13/52 (25%)

Query: 1741 EESTARNLNQQQQQQQQQQQQQQQQQ-------------QQQQQQQQQQVAA 1779
            ++   +   QQQQQQQQQQQQQQQQQ             QQQQQQQQQQ+AA
Sbjct: 186  QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 237



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 22/40 (55%), Positives = 28/40 (70%)

Query: 1741 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAA 1780
            ++   +   QQQQQQQQQQ   +Q ++QQQQQQQQQ  AA
Sbjct: 198  QQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 237



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 24/45 (53%), Positives = 28/45 (62%), Gaps = 8/45 (17%)

Query: 1741 EESTARNLNQQQQQQQQQQQQ--------QQQQQQQQQQQQQQQV 1777
            ++   +   QQQQQQQQQQQQ        QQQQQQQQQQ   QQ+
Sbjct: 196  QQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 240



 Score = 35.0 bits (79), Expect = 0.66
 Identities = 23/60 (38%), Positives = 35/60 (58%), Gaps = 3/60 (5%)

Query: 1720 QELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQ---QQQQQQQQQQQQQ 1776
            Q++   +++ V +   L    ++  A  L QQQ Q+  ++QQ+Q   Q  QQQQQQQQQQ
Sbjct: 127  QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186



 Score = 33.5 bits (75), Expect = 1.9
 Identities = 20/32 (62%), Positives = 20/32 (62%), Gaps = 8/32 (25%)

Query: 1750 QQQQQQQQQQ--------QQQQQQQQQQQQQQ 1773
            QQQQQQQQQQ        QQQ  Q QQ QQQQ
Sbjct: 225  QQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQ 256


>gi|110347429 mediator complex subunit 12 [Homo sapiens]
          Length = 2177

 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 32/79 (40%), Positives = 44/79 (55%)

Query: 1714 RSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQ 1773
            + + Q+Q+   + ++  +    + +  ++   R   QQQQQQQQQQQQQQQQQQQQQQQ 
Sbjct: 2057 QQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQH 2116

Query: 1774 QQQVAAAAGAATEHPPGSP 1792
            QQQ    A      P   P
Sbjct: 2117 QQQQQQQAAPPQPQPQSQP 2135



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 32/78 (41%), Positives = 45/78 (57%)

Query: 1714 RSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQ 1773
            + + Q+Q+   + ++  +   + +R  ++       QQQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 2056 QQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQ 2115

Query: 1774 QQQVAAAAGAATEHPPGS 1791
             QQ      A  +  P S
Sbjct: 2116 HQQQQQQQAAPPQPQPQS 2133



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 30/39 (76%), Positives = 32/39 (82%)

Query: 1737 LRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQ 1775
            ++A   STA    QQQQQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 2038 VQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQ 2076



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 25/28 (89%), Positives = 26/28 (92%)

Query: 1750 QQQQQQQQQQQQQQQQQQQQQQQQQQQV 1777
            QQQQQQQQQQQQQQQQQQQQQQQQQ  +
Sbjct: 2052 QQQQQQQQQQQQQQQQQQQQQQQQQYHI 2079



 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 31/64 (48%), Positives = 36/64 (56%), Gaps = 13/64 (20%)

Query: 1726 VEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQ-------------QQQQQQQQ 1772
            V+  VR+   L    ++   +   QQQQQQQQQQQQQQQ             QQQQQQQQ
Sbjct: 2038 VQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQ 2097

Query: 1773 QQQQ 1776
            QQQQ
Sbjct: 2098 QQQQ 2101



 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 23/37 (62%), Positives = 28/37 (75%)

Query: 1741 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQV 1777
            ++   +   QQQQQQQQQQQQQQQQQ   +QQQQQQ+
Sbjct: 2051 QQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQI 2087



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 30/67 (44%), Positives = 34/67 (50%), Gaps = 22/67 (32%)

Query: 1736 LLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQ----------------------Q 1773
            +LR  ++   +   QQQQQQQQQQQQQQQ QQQQQQQ                      Q
Sbjct: 2087 ILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQ 2146

Query: 1774 QQQVAAA 1780
            QQQ  AA
Sbjct: 2147 QQQQTAA 2153



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 19/78 (24%)

Query: 1716 EAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQ------------ 1763
            + Q+Q++L + ++  +      +  ++   +   QQQQQQ QQQQQQQ            
Sbjct: 2081 QQQQQQILRQQQQQQQQ-----QQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQP 2135

Query: 1764 --QQQQQQQQQQQQQVAA 1779
              Q+Q  QQ QQQQQ AA
Sbjct: 2136 QFQRQGLQQTQQQQQTAA 2153


>gi|33286444 mastermind-like 2 [Homo sapiens]
          Length = 1156

 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 32/52 (61%), Positives = 36/52 (69%)

Query: 1744 TARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSA 1795
            T +   QQQQQQQQQQQQQQQQQQQQQQQQQQQ  ++  A  +    S  SA
Sbjct: 587  TQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISA 638



 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 29/49 (59%), Positives = 35/49 (71%)

Query: 1731 RNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAA 1779
            +N   LL   ++   +   QQQQQQQQQQQQQQQQQQQQQQQQQ  ++A
Sbjct: 578  QNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISA 626



 Score = 58.2 bits (139), Expect = 7e-08
 Identities = 28/63 (44%), Positives = 43/63 (68%)

Query: 1714 RSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQ 1773
            + + Q+Q+   + ++  +  + +    ++    +++ QQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 602  QQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQ 661

Query: 1774 QQQ 1776
            QQQ
Sbjct: 662  QQQ 664



 Score = 58.2 bits (139), Expect = 7e-08
 Identities = 30/75 (40%), Positives = 47/75 (62%)

Query: 1714 RSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQ 1773
            + + Q+Q+   + ++  ++     +  ++ ++ +  QQQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 604  QQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQ 663

Query: 1774 QQQVAAAAGAATEHP 1788
            QQ  +  A +    P
Sbjct: 664  QQPSSQPAQSLPSQP 678



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 30/76 (39%), Positives = 46/76 (60%)

Query: 1714 RSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQ 1773
            + + Q+Q+   + ++  +  +   +  ++  +    QQQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 603  QQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQ 662

Query: 1774 QQQVAAAAGAATEHPP 1789
            QQQ ++    +    P
Sbjct: 663  QQQPSSQPAQSLPSQP 678



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 28/41 (68%), Positives = 33/41 (80%)

Query: 1736 LLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1776
            +L +  + +  +  QQQQQQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 574  VLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQ 614



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 30/75 (40%), Positives = 45/75 (60%)

Query: 1714 RSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQ 1773
            + + Q+Q+   + ++  +     + A ++   ++    QQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 601  QQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQ 660

Query: 1774 QQQVAAAAGAATEHP 1788
            QQQ   ++  A   P
Sbjct: 661  QQQQQPSSQPAQSLP 675



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 30/54 (55%), Positives = 34/54 (62%), Gaps = 5/54 (9%)

Query: 1744 TARNLNQQQ-----QQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSP 1792
            +A+   QQQ     QQQQQQQQQQQQQQQQQQQQQQQQ    +    +  P  P
Sbjct: 625  SAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQP 678



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 31/75 (41%), Positives = 43/75 (57%), Gaps = 5/75 (6%)

Query: 1741 EESTARNLNQQQQQQ-----QQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSA 1795
            ++ ++ +  QQQQQQ     QQQQQQQQQQQQQQQQQQQQQ       +++     P+  
Sbjct: 619  QQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQP 678

Query: 1796 TVMSTFTHSLKTLIK 1810
             + S      K L++
Sbjct: 679  LLRSPLPLQQKLLLQ 693



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 29/54 (53%), Positives = 36/54 (66%), Gaps = 4/54 (7%)

Query: 1732 NYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQ----QQQQQQQVAAAA 1781
            +YT   +  ++   +   QQQQQQQQQQQQQQQQQQQ     QQQQQQQ + +A
Sbjct: 585  HYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISA 638



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 30/76 (39%), Positives = 37/76 (48%), Gaps = 17/76 (22%)

Query: 1741 EESTARNLNQQQQQQQQQQQQ-----------------QQQQQQQQQQQQQQQVAAAAGA 1783
            ++   +   QQQQQQQQQQQQ                 QQQQQQQQQQQQQQQ       
Sbjct: 601  QQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQ 660

Query: 1784 ATEHPPGSPTSATVMS 1799
              +  P S  + ++ S
Sbjct: 661  QQQQQPSSQPAQSLPS 676



 Score = 36.2 bits (82), Expect = 0.30
 Identities = 75/388 (19%), Positives = 147/388 (37%), Gaps = 34/388 (8%)

Query: 956  EEQVSELRDNLPKEV-----RLSPKLILDPKSSVTPAIISAALQQVVHNKSLVTAGGALG 1010
            + Q S  R +LP E        SP L   P  S      SA     + N +L T+     
Sbjct: 347  QSQRSTPRPSLPMEKIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPS 406

Query: 1011 NPPSRGERRLEASMGRPEVSMMSSSASKNLKFKISPSAPETSWNSQHQLGAEVSSSPRAP 1070
             P S+ + +  +   R   S    S ++ LK +I+ +  + +   QHQ   + ++    P
Sbjct: 407  VPQSQAQPQTGSGASRALPSWQEVSHAQQLK-QIAANRQQHARMQQHQQQHQPTNWSALP 465

Query: 1071 TGSRADSLHLSQQEDSLPVQNFPPKSYLLRTSRESVGKQATGEVAGKGGPVGGKPTLQKQ 1130
            + +        Q++  +P  +F  +++  ++S         G   G G        + K 
Sbjct: 466  SSAGPSPGPFGQEK--IPSPSFGQQTFSPQSS------PMPGVAGGSGQSKVMANYMYKA 517

Query: 1131 GTISSQGEKAQLESTPKRSKLEETSLVPRATYPMALQSPSCQSRSHSPSCQPHGHSPSSQ 1190
            G  S+QG    +    K   L  + +           +P         + +P  H  S Q
Sbjct: 518  GP-SAQGGHLDVLMQQKPQDLSRSFI----------NNPHPAMEPRQGNTKPLFHFNSDQ 566

Query: 1191 SRGQSPSCQPRGQSP----LRSQAASRQVSTMPSRKLETTLNGAHSTSEGPAKPKSSRGP 1246
            +  Q PS  P    P       Q   +Q      ++ +          +   + +SS   
Sbjct: 567  ANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISA 626

Query: 1247 FRLRNLFSATFPTRQKKETDERQAQLQKVKQYELEFLEELLKPPSQGELPGTEYLQPPAP 1306
             + +   S+    +Q+++  ++Q Q Q+ +Q + +  ++    P+Q  LP    L+ P P
Sbjct: 627  QQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQS-LPSQPLLRSPLP 685

Query: 1307 GRCSC---QLRSSPVQ-QGPGMSREQRR 1330
             +      Q+++ P+   G  +S++QR+
Sbjct: 686  LQQKLLLQQMQNQPIAGMGYQVSQQQRQ 713


>gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens]
          Length = 1420

 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 39/89 (43%), Positives = 50/89 (56%), Gaps = 7/89 (7%)

Query: 1712 IVRSEAQRQELLAKVEEVVRNYTFLL--RAAEESTARNLNQQQQQQQQQQQQQQQQQQQQ 1769
            ++R   Q Q+     + V +    LL     ++  A  + QQQQQQQQQQQQQQQQQQQQ
Sbjct: 1205 VMRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQ 1264

Query: 1770 QQQQQQQVAAAAGAATEHPPGSPTSATVM 1798
            QQQQQQQ   A       PP + T++  M
Sbjct: 1265 QQQQQQQQTQAFS-----PPPNVTASPSM 1288


>gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens]
          Length = 1424

 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 33/58 (56%), Positives = 39/58 (67%), Gaps = 5/58 (8%)

Query: 1741 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVM 1798
            ++  A  + QQQQQQQQQQQQQQQQQQQQQQQQQQQ   A       PP + T++  M
Sbjct: 1240 QQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFS-----PPPNVTASPSM 1292



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 28/55 (50%), Positives = 35/55 (63%)

Query: 1720 QELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQ 1774
            Q +  +  E++ ++    R A     +   QQQQQQQQQQQQQQQQQQQQQQQ Q
Sbjct: 1224 QMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQ 1278



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 23/45 (51%), Positives = 29/45 (64%)

Query: 1732 NYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1776
            N   + + + E  + +  QQ+     QQQQQQQQQQQQQQQQQQQ
Sbjct: 1222 NAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQ 1266



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 21/45 (46%), Positives = 27/45 (60%)

Query: 1736 LLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAA 1780
            ++   ++   +   QQQQQQQQQQQQQQQQQQ Q       V A+
Sbjct: 1245 MMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTAS 1289



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 22/52 (42%), Positives = 29/52 (55%)

Query: 1717 AQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQ 1768
            AQR   L       +    +++  ++   +   QQQQQQQQQQQQQQQQQ Q
Sbjct: 1227 AQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQ 1278


>gi|55956910 meningioma  1 [Homo sapiens]
          Length = 1320

 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 30/36 (83%), Positives = 32/36 (88%)

Query: 1746 RNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAA 1781
            ++L QQQQQQQQQQQQQQQQQQQQQQQQQQQ   AA
Sbjct: 520  QSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAA 555



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 30/44 (68%), Positives = 33/44 (75%)

Query: 1736 LLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAA 1779
            L   A +  +    QQQQQQQQQQQQQQQQQQQQQQQQQ+Q AA
Sbjct: 512  LQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAA 555



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 27/33 (81%), Positives = 27/33 (81%)

Query: 1752 QQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1784
            QQQQQQQQQQQQQQQQQQQQQQQQQ      AA
Sbjct: 523  QQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAA 555



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 20/39 (51%), Positives = 27/39 (69%)

Query: 1741 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAA 1779
            ++   +   QQQQQQQQQQQQQQQQQ+Q      +Q+A+
Sbjct: 525  QQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMAS 563



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 18/32 (56%), Positives = 20/32 (62%)

Query: 1738 RAAEESTARNLNQQQQQQQQQQQQQQQQQQQQ 1769
            RAA       ++ Q  QQQ QQQQQ QQQQQQ
Sbjct: 278  RAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQ 309



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 16/25 (64%), Positives = 18/25 (72%)

Query: 1748 LNQQQQQQQQQQQQQQQQQQQQQQQ 1772
            L++   Q  QQQ QQQQQ QQQQQQ
Sbjct: 285  LSKMHAQPPQQQPQQQQQPQQQQQQ 309



 Score = 33.5 bits (75), Expect = 1.9
 Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 3/51 (5%)

Query: 1741 EESTARNLNQQQQQQQQQQQQQQQQ---QQQQQQQQQQQVAAAAGAATEHP 1788
            ++   +   QQQQQQQQQQQ+Q      +Q   + QQQ++     A   HP
Sbjct: 531  QQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHP 581



 Score = 32.7 bits (73), Expect = 3.3
 Identities = 18/36 (50%), Positives = 19/36 (52%)

Query: 1755 QQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPG 1790
            Q  QQQ QQQQQ QQQQQQ          A + P G
Sbjct: 291  QPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVG 326


>gi|189491748 ataxin 1 [Homo sapiens]
          Length = 815

 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 34/57 (59%), Positives = 38/57 (66%), Gaps = 6/57 (10%)

Query: 1742 ESTARNLNQQQQQQQQQQQQ---QQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSA 1795
            ++      QQQQQQQQQQQQ   QQQQQQQQQQQQQQ ++ A G  T   PGSP  A
Sbjct: 189  QTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLIT---PGSPPPA 242


>gi|51479158 ataxin 1 [Homo sapiens]
          Length = 815

 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 34/57 (59%), Positives = 38/57 (66%), Gaps = 6/57 (10%)

Query: 1742 ESTARNLNQQQQQQQQQQQQ---QQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSA 1795
            ++      QQQQQQQQQQQQ   QQQQQQQQQQQQQQ ++ A G  T   PGSP  A
Sbjct: 189  QTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLIT---PGSPPPA 242


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 173/749 (23%), Positives = 261/749 (34%), Gaps = 137/749 (18%)

Query: 798  ESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKDSLLARKDLPFRIQSCAAQ 857
            +S+  SGH  +SSEL+  +   + M  +Q+        ++   L A    P R +S +A 
Sbjct: 1374 QSTRSSGH--SSSELSPDAVEKAGMSSNQS--------ISSPVLDAVPRTPSRERSSSAS 1423

Query: 858  A------VLTAPYSLGRPDPNPSLQPIA--------TGQSPGPPGARRKLPQSEGQVQGE 903
            +      +   P    R   +P L+  +        +G SPG     + +P++  + + E
Sbjct: 1424 SPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPG----MKDIPRTPSRGRSE 1479

Query: 904  RTYSLAVHPALSPQLSEQKNLSLLSPVPEDK--GPGHTRAGLEMSLRAATSSLSEEQVSE 961
               S    P   PQ    ++ S  SP   +K   P   R+G E S+         +Q + 
Sbjct: 1480 CDSS--PEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSV---------DQKTV 1528

Query: 962  LRDNLPKEVRLSPKLILDPKSSVTPAIISAALQQVVHNKSLVTAGGALGNPPSRGERRLE 1021
             R  L +  R      LD K S +P       Q+   + S   +      P  +  R   
Sbjct: 1529 ARTPLGQRSRSGSSQELDVKPSASP-------QERSESDSSPDSKAKTRTPLRQRSR--- 1578

Query: 1022 ASMGRPEVSMMSSSASKNLKFKISPSAPETSWNSQH-QLGAEVSSSPRAP---------- 1070
             S   PEV   S  + +  +   SP   +    +   Q G++ S  P+AP          
Sbjct: 1579 -SGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSR 1637

Query: 1071 TGS----RADSLHLSQQEDSLPVQNFPPKSYLLRT-SRESVGKQATGEVAGKGGPVGGKP 1125
            +GS    R  S   S   +S P    PPKS   R  SR S   +       +       P
Sbjct: 1638 SGSSSKGRGPSPEGSSSTESSP--EHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSP 1695

Query: 1126 TLQKQGTISSQGEKAQLESTPKRSKLEETSLVPRATYPMALQSPSCQSRSHSPSCQPHGH 1185
             L ++  +S +   A   S   RS+       PR     ++ SP    +S S   +    
Sbjct: 1696 ELTRKARLSRRSRSAS-SSPETRSRTP-----PRHRRSPSVSSPEPAEKSRSSRRRRSAS 1749

Query: 1186 SPSSQS---RGQSPSCQPRGQSPLRSQAAS---------------------RQVSTMPSR 1221
            SP +++   RG+SPS +PRG    RS++                       RQ S   SR
Sbjct: 1750 SPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSR 1809

Query: 1222 KLETTLNGAHSTSEGPAKPKSSRGPFRLRNLFSATFPTRQKKETDERQAQLQKVKQYELE 1281
                   G+   S  PA+ +SSR   R R   S T PT +K+          K  +    
Sbjct: 1810 VTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRAS 1869

Query: 1282 FLEELLKPPSQGELPGT---EYLQPPAPGRCSCQLRSSPVQQGPGMSR--------EQRR 1330
                          P T      + P   R   + R+SPV +    SR          R 
Sbjct: 1870 --------------PATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRA 1915

Query: 1331 SCDCKRICRGGRPQAT----QTPVPSLRGRERDRVLPSQRQPEAGPGVSLSSPINVQRIR 1386
            S   +R  R   P  T    ++  P+ R R R R  P  R+       S S    V R R
Sbjct: 1916 SPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRR------SRSRTPPVTRRR 1969

Query: 1387 STSLESRECRSDPESGVSCLTTCASGGECLGAPNYRKLMRRYSISELDQGDRASLTSDVY 1446
            S S  S   R    S  S +T   S          R   R   ++      R        
Sbjct: 1970 SRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRR 2029

Query: 1447 PHPPLGMLPREAKEVEASLPIALGPKSRS 1475
                  +LPR  K   +  P+A+  +SRS
Sbjct: 2030 SRSRTPLLPR--KRSRSRSPLAIRRRSRS 2056



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 93/405 (22%), Positives = 158/405 (39%), Gaps = 43/405 (10%)

Query: 1011 NPPSRGERRLEASMGRPEVSMMSSSASKNLKFKISPSAPETSWNSQHQLGAEVSSSPRAP 1070
            NPPS      + S  +    +  SS+S++     SP +P+ +  S+H   +  S  P   
Sbjct: 392  NPPSEASPTRDRSPPKSPEKLPQSSSSES-----SPPSPQPTKVSRHASSSPESPKPAPA 446

Query: 1071 TGSRADSLHLSQQEDSLPVQNFPPKSYLLRTSRESVGKQATGEVAGKGGPVGGKPTLQKQ 1130
             GS  +       ++    +    KS+    SR  +G+  +   A +G      PT +  
Sbjct: 447  PGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRR-MGRSRSPATAKRGRSRSRTPTKRGH 505

Query: 1131 GTISS----QGEKAQLESTPKRSKLEETSLVPRATYPMALQSPSCQSRSHSPSCQ---PH 1183
                S    +   AQ     +  +    S  P+   P   +S + Q R  S S +    H
Sbjct: 506  SRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQR--PGWSRSRNTQRRGRSRSARRGRSH 563

Query: 1184 GHSPSSQSRGQSPSCQPRGQSPLRSQAASRQVSTMPSRKLETTLNGAHSTSEGPAK--PK 1241
              SP+++ R +S +   RG+S  R+ A  R  S  P+R+         S S  PA+    
Sbjct: 564  SRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRR--------RSRSRTPARRGRS 615

Query: 1242 SSRGPFRLRNLFSATFPTRQKKETDERQAQLQKVKQYELEFLEELLKPPSQGELPGTEYL 1301
             SR P R R+   +    R +  +  R++   + +            P  +G        
Sbjct: 616  RSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGR------S 669

Query: 1302 QPPAPGRCSCQLRS-SPVQQGPGMSREQRRSCDCKR-ICRGGRPQATQTPVPSLRGR--- 1356
            +   P R S + RS +P ++G   SR  RR     R + R GR   + +  P  RGR   
Sbjct: 670  RSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGR---SHSRTPQRRGRSGS 726

Query: 1357 ---ERDRVLPSQRQPEAGPGVSL-SSPINVQRIRSTSLESRECRS 1397
                +++   SQR+  +     +  S I+ +R RS S    + +S
Sbjct: 727  SSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKS 771



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 98/407 (24%), Positives = 151/407 (37%), Gaps = 57/407 (14%)

Query: 1014 SRGERRLEASMGRPEV--SMMSSSASKNLKFKISPSAPETSWNSQHQLGAEVSSSPRAPT 1071
            SR  +R   S   PE+  S +SS  S++L      S+P +   S+  L   +S S   P 
Sbjct: 734  SRTSQRRSRSNSSPEMKKSRISSRRSRSL------SSPRSKAKSRLSLRRSLSGSSPCPK 787

Query: 1072 GSRADSLHLSQQEDSLPVQNF-------------PPKSYLLRTSRESVGKQATGEVAGKG 1118
                     S+   S P                 PPK      SR+S    +       G
Sbjct: 788  QKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSG 847

Query: 1119 GPVGGKPTLQKQGTISSQGEKAQLESTPKRSKLEETSLVPRATYPMALQSPSCQSRSHSP 1178
             P        +QG+I+S     Q   TP+R    E+S  P     +  ++PS  S S S 
Sbjct: 848  TP-------PRQGSITSPQANEQ-SVTPQRRSCFESSPDPE----LKSRTPSRHSCSGSS 895

Query: 1179 SCQPHGHSPSSQSRGQSPSCQPRGQSPLRSQAASRQVSTMPS-RKLETTLNGAHSTSEGP 1237
              +    +P  QS  +S S QP+ ++ +  +  S   S+ PS  ++ +      S S  P
Sbjct: 896  PPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSP 955

Query: 1238 AKPKSSRGPFRLRNLFSATFPTRQKKETDERQAQLQKVKQYELEFLEELLKPPSQGELPG 1297
                 SR   R  +  S++  T+ K ET  RQ+    +  Y      +   PP     P 
Sbjct: 956  CSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYP---KVKAQTPPG----PS 1008

Query: 1298 TEYLQPPAPGRCSCQLRSSPVQQGPGMSREQRRSCDCKRICRGGRPQATQTPVPSLRGRE 1357
                + P P   S   + S VQ  PG          C  +     P  +   V SL+ + 
Sbjct: 1009 LSGSKSPCPQEKS---KDSLVQSCPGSLSL------CAGVKSSTPPGESYFGVSSLQLKG 1059

Query: 1358 RDRVLPSQRQPEAGPGVSLSSPINVQRIRSTSLESRECRSDPESGVS 1404
            + +  P  R   + P V  S         S SL+S+  ++ P+ G S
Sbjct: 1060 QSQTSPDHRSDTSSPEVRQS------HSESPSLQSKS-QTSPKGGRS 1099



 Score = 39.3 bits (90), Expect = 0.035
 Identities = 79/326 (24%), Positives = 114/326 (34%), Gaps = 77/326 (23%)

Query: 1172 QSRSHSPSCQPHGHSPSSQSRGQSPSCQPRGQSPLRSQAASR----------QVSTMPSR 1221
            +SRS S   +   HS + Q RG+S S   R      SQ  SR          ++S+  SR
Sbjct: 701  RSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSR 760

Query: 1222 KLETTLNGAHS-------------------------TSEGPAKPKS-SRGPFRLRNLFSA 1255
             L +  + A S                         +  G ++PK+ SR P R R+  S+
Sbjct: 761  SLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPR-RSRSSS 819

Query: 1256 TFPTRQKKETDERQAQLQKVKQYELEFLEELLKPPSQGELPGTE-YLQPPAPGRCSCQLR 1314
            + P +QK +T  RQ+        ++    +   PP QG +   +   Q   P R SC   
Sbjct: 820  SPPPKQKSKTPSRQSHSSSSPHPKV----KSGTPPRQGSITSPQANEQSVTPQRRSC-FE 874

Query: 1315 SSPVQQGPGMSREQRRSCDCKRICRGGRPQATQTPVPSLRGRERDRVLPSQRQPEAGPGV 1374
            SSP         E +     +  C G  P   ++  P                P   P  
Sbjct: 875  SSP-------DPELKSRTPSRHSCSGSSPPRVKSSTP----------------PRQSPSR 911

Query: 1375 SLSSPINVQRIRSTSLESRECRSDPE-SGVSCLTTCASGGECLGAPNYR-KLMRRYSISE 1432
            S S    V+ I S    S    S P  S V+  TT           N   +L+ RYS S 
Sbjct: 912  SSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSG 971

Query: 1433 LDQGD---------RASLTSDVYPHP 1449
                D         R S +  + P+P
Sbjct: 972  SSSPDTKVKPETPPRQSHSGSISPYP 997



 Score = 38.9 bits (89), Expect = 0.046
 Identities = 95/420 (22%), Positives = 153/420 (36%), Gaps = 51/420 (12%)

Query: 861  TAPYSLGRPDPNPSLQPIATGQSPGPPGARRKLPQSEGQVQGERTYSLAVHPA------L 914
            T P +   P  + + Q  A+    GP  A    P +   + G RT + A+ PA      +
Sbjct: 2316 TPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVN---IAGSRT-AAALAPASLTSARM 2371

Query: 915  SPQLSEQKNLSLLSPVPE-DKGPGHTRAGLEMSLRAAT--SSLSEEQVSELRDNLPKE-- 969
            +P LS     S   P+   ++  G T   L    R+ T  S+ S+ +++  R   P    
Sbjct: 2372 APALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRM 2431

Query: 970  -----VRLSPKLILDPKSSVTPAI------ISAALQQVVHNKSLVTAGGALGNPPSRGER 1018
                   L P     P+S V  A       + A    V  ++SL ++G       S G+ 
Sbjct: 2432 GQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSL-SSGAVATTTSSAGDH 2490

Query: 1019 RLEASMGRP--------EVSMMSSSASKNLKFKISPSAPETSWNSQHQLGAEVSSSPRAP 1070
                S+  P        E    + +   +    + P+    S +S     +  SSS  + 
Sbjct: 2491 NGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSS 2550

Query: 1071 TGSRADSLHLSQQE-DSLPVQNFPPKSYLLRTSRESVGKQATGEVAGKGGPVGGKPTLQK 1129
            + S +     S  E  SLPVQ   P+  L R    +    A  E   +G P   +PT  K
Sbjct: 2551 SSSSSSGSSSSDSEGSSLPVQ---PEVALKRVPSPT---PAPKEAVREGRPP--EPTPAK 2602

Query: 1130 QGTISSQGEKAQLESTPKRSKLEETSLVPRATYPMALQSPSCQSRSHSPS-----CQPHG 1184
            +   SS    +   S+   S    +S    ++   +  S S  S S SP+       P  
Sbjct: 2603 RKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKP 2662

Query: 1185 HSPSSQSRGQSPSCQPRGQSPLRSQAASRQVSTMPSRKLETTLNGAHSTSEGPAKPKSSR 1244
             SP     G+  S  PR   P+ S   SR +S  P  +   +   +    +  +  + SR
Sbjct: 2663 ASPKKPPPGERRSRSPR--KPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSR 2720



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 116/529 (21%), Positives = 191/529 (36%), Gaps = 87/529 (16%)

Query: 780  HPPPPQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKD 839
            H   PQ  G    ++     S  S   + S+   +M +  S +   ++ +    +   K 
Sbjct: 714  HSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKK--SRISSRRSRSLSSPRSKAKS 771

Query: 840  SLLARKDLPFRIQSCAAQAVLTAPYSLGRPDPNPSLQPIATGQSPG---------PPGAR 890
             L  R+ L      C  Q   T P    R   + S QP A  ++P          PP  +
Sbjct: 772  RLSLRRSLSGS-SPCPKQKSQTPP----RRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQK 826

Query: 891  RKLPQSEGQVQGERTYSLAVHPAL------------SPQLSEQ------KNLSLLSPVPE 932
             K P  +         S + HP +            SPQ +EQ      ++    SP PE
Sbjct: 827  SKTPSRQSHS------SSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPE 880

Query: 933  DKGPGHTRAGLEMSLRAATSSLSEEQVSELRDNLPKEVRLSPKLILDPKSSVTPAIISAA 992
             K    +R     S      S +  + S  R + P+      K I+ P+        S +
Sbjct: 881  LKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQP---KVKAIISPRQRSHSGSSSPS 937

Query: 993  LQQVVHNKSLVTAGGALGNPPSRGERRLEASMGRPEVSMMSSSASKNLKFKISPSAPETS 1052
              +V    +   +     +P S  E RL        +   S S S +   K+ P  P   
Sbjct: 938  PSRVTSRTTPRRSRSV--SPCSNVESRL--------LPRYSHSGSSSPDTKVKPETPPRQ 987

Query: 1053 WNSQHQLGAEVSSSPRAPTGSRADSLHLSQQEDSLPVQNFPPKSYLLRTSRESVGKQATG 1112
             +S       +S  P+    +      LS  +   P +           S++S+ +   G
Sbjct: 988  SHS-----GSISPYPKVKAQTPPGP-SLSGSKSPCPQEK----------SKDSLVQSCPG 1031

Query: 1113 EVAGKGGPVGGKPTLQKQGTISSQGEKAQLESTPK-RSKLEETSLVPRATYPMALQSPSC 1171
             ++   G     P  +    +SS   K Q +++P  RS      +    +   +LQS S 
Sbjct: 1032 SLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQ 1091

Query: 1172 ------QSRSHSPSCQPHGHSPSSQSRGQ---SPSCQPRGQSPLRS--QAASRQVSTMPS 1220
                  +SRS SP  +    SP  Q RG+   SP  +  G SP +S  Q+ S    T+ S
Sbjct: 1092 TSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLK-SGMSPEQSRFQSDSSSYPTVDS 1150

Query: 1221 RKL--ETTLNGAHSTSEG--PAKPKSSRGPFRLRNLFSATFPTRQKKET 1265
              L  ++ L  A S  +   P +  ++  P R ++ FS  FP + + E+
Sbjct: 1151 NSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFS-PFPVQDRPES 1198


>gi|226442791 runt-related transcription factor 2 isoform b [Homo
            sapiens]
          Length = 499

 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 29/32 (90%), Positives = 30/32 (93%)

Query: 1753 QQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1784
            QQQQQQQQQQQQQQQQQQQQQQQ+ AAAA AA
Sbjct: 49   QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAA 80



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 29/33 (87%), Positives = 30/33 (90%)

Query: 1752 QQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1784
            QQQQQQQQQQQQQQQQQQQQQQQ+  AAAA AA
Sbjct: 49   QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAA 81



 Score = 58.2 bits (139), Expect = 7e-08
 Identities = 29/34 (85%), Positives = 30/34 (88%)

Query: 1751 QQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1784
            QQQQQQQQQQQQQQQQQQQQQQQ+   AAAA AA
Sbjct: 49   QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAA 82



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 29/35 (82%), Positives = 30/35 (85%)

Query: 1750 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1784
            QQQQQQQQQQQQQQQQQQQQQQQ+    AAAA AA
Sbjct: 49   QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAA 83



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 30/56 (53%), Positives = 36/56 (64%)

Query: 1755 QQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVMSTFTHSLKTLIK 1810
            QQQQQQQQQQQQQQQQQQQQQQ  AAA AA      +  +A       H  +T+++
Sbjct: 49   QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVE 104



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 28/35 (80%), Positives = 29/35 (82%)

Query: 1750 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1784
            QQQQQQQQQQQQQQQQQQQQQQ+     AAAA AA
Sbjct: 50   QQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAA 84



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 27/35 (77%), Positives = 28/35 (80%)

Query: 1750 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1784
            QQQQQQQQQQQQQQQQQQQQQ+      AAAA AA
Sbjct: 51   QQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAA 85



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 28/45 (62%), Positives = 29/45 (64%)

Query: 1745 ARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPP 1789
            A    QQQQQQQQQQQQQQQQQQQQ+       AAAA AA    P
Sbjct: 47   AAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVP 91



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 22/50 (44%), Positives = 25/50 (50%)

Query: 1740 AEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPP 1789
            A +   +   QQQQQQQQQQQQQQQ+            AAAA      PP
Sbjct: 47   AAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPP 96



 Score = 38.5 bits (88), Expect = 0.060
 Identities = 22/61 (36%), Positives = 30/61 (49%)

Query: 1739 AAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVM 1798
            AA++   +   QQQQQQQQQQQQQQ+             AAAA      P  + T   ++
Sbjct: 47   AAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEII 106

Query: 1799 S 1799
            +
Sbjct: 107  A 107



 Score = 33.5 bits (75), Expect = 1.9
 Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 6/53 (11%)

Query: 1736 LLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHP 1788
            ++ A ++   +   QQQQQQ      QQQQQQQ+        AAAA AA   P
Sbjct: 45   VVAAQQQQQQQQQQQQQQQQ------QQQQQQQEAAAAAAAAAAAAAAAAAVP 91


>gi|226442783 runt-related transcription factor 2 isoform a [Homo
            sapiens]
          Length = 521

 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 29/32 (90%), Positives = 30/32 (93%)

Query: 1753 QQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1784
            QQQQQQQQQQQQQQQQQQQQQQQ+ AAAA AA
Sbjct: 49   QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAA 80



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 29/33 (87%), Positives = 30/33 (90%)

Query: 1752 QQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1784
            QQQQQQQQQQQQQQQQQQQQQQQ+  AAAA AA
Sbjct: 49   QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAA 81



 Score = 58.2 bits (139), Expect = 7e-08
 Identities = 29/34 (85%), Positives = 30/34 (88%)

Query: 1751 QQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1784
            QQQQQQQQQQQQQQQQQQQQQQQ+   AAAA AA
Sbjct: 49   QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAA 82



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 29/35 (82%), Positives = 30/35 (85%)

Query: 1750 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1784
            QQQQQQQQQQQQQQQQQQQQQQQ+    AAAA AA
Sbjct: 49   QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAA 83



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 30/56 (53%), Positives = 36/56 (64%)

Query: 1755 QQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVMSTFTHSLKTLIK 1810
            QQQQQQQQQQQQQQQQQQQQQQ  AAA AA      +  +A       H  +T+++
Sbjct: 49   QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVE 104



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 28/35 (80%), Positives = 29/35 (82%)

Query: 1750 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1784
            QQQQQQQQQQQQQQQQQQQQQQ+     AAAA AA
Sbjct: 50   QQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAA 84



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 27/35 (77%), Positives = 28/35 (80%)

Query: 1750 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1784
            QQQQQQQQQQQQQQQQQQQQQ+      AAAA AA
Sbjct: 51   QQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAA 85



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 28/45 (62%), Positives = 29/45 (64%)

Query: 1745 ARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPP 1789
            A    QQQQQQQQQQQQQQQQQQQQ+       AAAA AA    P
Sbjct: 47   AAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVP 91



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 22/50 (44%), Positives = 25/50 (50%)

Query: 1740 AEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPP 1789
            A +   +   QQQQQQQQQQQQQQQ+            AAAA      PP
Sbjct: 47   AAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPP 96



 Score = 38.5 bits (88), Expect = 0.060
 Identities = 22/61 (36%), Positives = 30/61 (49%)

Query: 1739 AAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVM 1798
            AA++   +   QQQQQQQQQQQQQQ+             AAAA      P  + T   ++
Sbjct: 47   AAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEII 106

Query: 1799 S 1799
            +
Sbjct: 107  A 107



 Score = 33.5 bits (75), Expect = 1.9
 Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 6/53 (11%)

Query: 1736 LLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHP 1788
            ++ A ++   +   QQQQQQ      QQQQQQQ+        AAAA AA   P
Sbjct: 45   VVAAQQQQQQQQQQQQQQQQ------QQQQQQQEAAAAAAAAAAAAAAAAAVP 91


>gi|66934969 runt-related transcription factor 2 isoform c [Homo
            sapiens]
          Length = 507

 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 29/32 (90%), Positives = 30/32 (93%)

Query: 1753 QQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1784
            QQQQQQQQQQQQQQQQQQQQQQQ+ AAAA AA
Sbjct: 35   QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAA 66



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 29/33 (87%), Positives = 30/33 (90%)

Query: 1752 QQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1784
            QQQQQQQQQQQQQQQQQQQQQQQ+  AAAA AA
Sbjct: 35   QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAA 67



 Score = 58.2 bits (139), Expect = 7e-08
 Identities = 29/34 (85%), Positives = 30/34 (88%)

Query: 1751 QQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1784
            QQQQQQQQQQQQQQQQQQQQQQQ+   AAAA AA
Sbjct: 35   QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAA 68



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 29/35 (82%), Positives = 30/35 (85%)

Query: 1750 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1784
            QQQQQQQQQQQQQQQQQQQQQQQ+    AAAA AA
Sbjct: 35   QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAA 69



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 30/56 (53%), Positives = 36/56 (64%)

Query: 1755 QQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVMSTFTHSLKTLIK 1810
            QQQQQQQQQQQQQQQQQQQQQQ  AAA AA      +  +A       H  +T+++
Sbjct: 35   QQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVE 90



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 28/35 (80%), Positives = 29/35 (82%)

Query: 1750 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1784
            QQQQQQQQQQQQQQQQQQQQQQ+     AAAA AA
Sbjct: 36   QQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAA 70



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 27/35 (77%), Positives = 28/35 (80%)

Query: 1750 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1784
            QQQQQQQQQQQQQQQQQQQQQ+      AAAA AA
Sbjct: 37   QQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAA 71



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 28/45 (62%), Positives = 29/45 (64%)

Query: 1745 ARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPP 1789
            A    QQQQQQQQQQQQQQQQQQQQ+       AAAA AA    P
Sbjct: 33   AAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVP 77



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 22/50 (44%), Positives = 25/50 (50%)

Query: 1740 AEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPP 1789
            A +   +   QQQQQQQQQQQQQQQ+            AAAA      PP
Sbjct: 33   AAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPP 82



 Score = 38.5 bits (88), Expect = 0.060
 Identities = 22/61 (36%), Positives = 30/61 (49%)

Query: 1739 AAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVM 1798
            AA++   +   QQQQQQQQQQQQQQ+             AAAA      P  + T   ++
Sbjct: 33   AAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEII 92

Query: 1799 S 1799
            +
Sbjct: 93   A 93



 Score = 33.5 bits (75), Expect = 1.9
 Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 6/53 (11%)

Query: 1736 LLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHP 1788
            ++ A ++   +   QQQQQQ      QQQQQQQ+        AAAA AA   P
Sbjct: 31   VVAAQQQQQQQQQQQQQQQQ------QQQQQQQEAAAAAAAAAAAAAAAAAVP 77


>gi|51702521 POU domain, class 3, transcription factor 2 [Homo
            sapiens]
          Length = 443

 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 33/57 (57%), Positives = 37/57 (64%), Gaps = 1/57 (1%)

Query: 1750 QQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHP-PGSPTSATVMSTFTHSL 1805
            QQQ QQQQQQQQQQQQQQQQQQQQQ+       AA  HP PG+  SA   +    S+
Sbjct: 125  QQQHQQQQQQQQQQQQQQQQQQQQQRPPHLVHHAANHHPGPGAWRSAAAAAHLPPSM 181



 Score = 31.2 bits (69), Expect = 9.6
 Identities = 21/61 (34%), Positives = 25/61 (40%), Gaps = 3/61 (4%)

Query: 1737 LRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAA---AGAATEHPPGSPT 1793
            L+   +   +   QQQQQQQQQQQQQ+                A   A AA   PP    
Sbjct: 124  LQQQHQQQQQQQQQQQQQQQQQQQQQRPPHLVHHAANHHPGPGAWRSAAAAAHLPPSMGA 183

Query: 1794 S 1794
            S
Sbjct: 184  S 184


>gi|56549696 E1A binding protein p400 [Homo sapiens]
          Length = 3122

 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 29/41 (70%), Positives = 31/41 (75%)

Query: 1748 LNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHP 1788
            L QQQQQQQQQQQQQQQQQQQQQQQQQQQ      +  + P
Sbjct: 2717 LRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVP 2757



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 27/30 (90%), Positives = 27/30 (90%)

Query: 1746 RNLNQQQQQQQQQQQQQQQQQQQQQQQQQQ 1775
            R   QQQQQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 2718 RQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 2747



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 27/29 (93%), Positives = 28/29 (96%)

Query: 1748 LNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1776
            L +QQQQQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 2716 LLRQQQQQQQQQQQQQQQQQQQQQQQQQQ 2744



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 24/27 (88%), Positives = 25/27 (92%)

Query: 1750 QQQQQQQQQQQQQQQQQQQQQQQQQQQ 1776
            Q  +QQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 2715 QLLRQQQQQQQQQQQQQQQQQQQQQQQ 2741



 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 36/98 (36%), Positives = 50/98 (51%), Gaps = 5/98 (5%)

Query: 1689 LAAITGSFQVLSSL--IETFVRLVFIVRSEAQRQELLAKVEEVVRNYTFLLRAAEESTAR 1746
            + ++T S  V ++L  ++T  R +    S+A   +L  K    +    F L   ++   +
Sbjct: 2669 VTSVTASAVVTTNLTPVQTPARSLVPQVSQATGVQLPGKT---ITPAHFQLLRQQQQQQQ 2725

Query: 1747 NLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1784
               QQQQQQQQQQQQQQQQQQQ     Q QV    G A
Sbjct: 2726 QQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQA 2763



 Score = 36.2 bits (82), Expect = 0.30
 Identities = 22/55 (40%), Positives = 26/55 (47%), Gaps = 8/55 (14%)

Query: 1741 EESTARNLNQQQQQQQQQQQQQQQ--------QQQQQQQQQQQQVAAAAGAATEH 1787
            ++   +   QQQQQQQQQQQQQQ          Q Q Q Q   Q+ A      EH
Sbjct: 2725 QQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEH 2779



 Score = 32.0 bits (71), Expect = 5.6
 Identities = 71/354 (20%), Positives = 134/354 (37%), Gaps = 30/354 (8%)

Query: 876  QPIATGQSPGPPGARRKLPQSEGQVQGERTYSLAVHPALSPQLSEQKNLSLLSPVPEDKG 935
            Q +     P PP A+   PQ   QVQ        V  +  PQ    +  ++ +P P    
Sbjct: 2786 QKLQMPPQPPPPQAQSAPPQPTAQVQ--------VQTSQPPQQQSPQLTTVTAPRPGALL 2837

Query: 936  PGHTRAGLEMS--LRAATSSLSEEQVSELRDNLPKEVRLSPKLILDPKSSVTPAIISA-A 992
             G T A L+++   R  TS L  +   + +   P +V L+      P  SV  A++S+  
Sbjct: 2838 TGTTVANLQVARLTRVPTSQLQAQGQMQTQAPQPAQVALAK----PPVVSVPAAVVSSPG 2893

Query: 993  LQQVVHNKSLVTAGGALGNPPSRGERRLEASMGRPEVSMMSSSASKNLKFKISPSAPETS 1052
            +  +  N + ++   A+G P     + + A     +  +     +   +  I P A +  
Sbjct: 2894 VTTLPMNVAGISV--AIGQPQKAAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQGP 2951

Query: 1053 WNSQHQLGAEVSSSPRAPTG-SRADSLHLSQQEDSLPVQNFPPKSYLLRTSRESVGKQAT 1111
               Q ++ A+  ++P A    + A    L  Q  + P+     K    +  +  +     
Sbjct: 2952 AAVQQKITAQQITTPGAQQKVAYAAQPALKTQFLTTPISQ-AQKLAGAQQVQTQIQVAKL 3010

Query: 1112 GEVAGKGGPVGGKPTLQKQGTISSQGEKAQLESTPKRSKLEETSLVPRAT-----YPMAL 1166
             +V  +  PV    ++Q+  + S Q     +  T   +  ++  ++P  T         L
Sbjct: 3011 PQVVQQQTPVA---SIQQVASASQQASPQTVALTQATAAGQQVQMIPAVTATAQVVQQKL 3067

Query: 1167 QSPSCQSRSHSPSCQPHGHSPSS-QSRGQSPSCQPRGQSPLRSQAASRQVSTMP 1219
                  + + +P   P   +P+   +   SPS QP+ Q  +R  A   +  T P
Sbjct: 3068 IQQQVVTTASAPLQTPGAPNPAQVPASSDSPSQQPKLQ--MRVPAVRLKTPTKP 3119


>gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens]
          Length = 1161

 Score = 58.2 bits (139), Expect = 7e-08
 Identities = 28/31 (90%), Positives = 30/31 (96%)

Query: 1746 RNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1776
            R+ +QQQQQQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 456  RHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQ 486



 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 23/28 (82%), Positives = 25/28 (89%)

Query: 1749 NQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1776
            ++   QQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 455  HRHPHQQQQQQQQQQQQQQQQQQQQQQQ 482



 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 23/30 (76%), Positives = 25/30 (83%)

Query: 1747 NLNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1776
            +L  +   QQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 452  HLQHRHPHQQQQQQQQQQQQQQQQQQQQQQ 481



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 22/31 (70%), Positives = 25/31 (80%)

Query: 1746 RNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1776
            + L+ Q +   QQQQQQQQQQQQQQQQQQQQ
Sbjct: 449  QQLHLQHRHPHQQQQQQQQQQQQQQQQQQQQ 479



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 20/40 (50%), Positives = 23/40 (57%)

Query: 1738 RAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQV 1777
            R   +   +   QQQQQQQQQQQQQQQQQQQ        +
Sbjct: 456  RHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHHHHHL 495



 Score = 41.2 bits (95), Expect = 0.009
 Identities = 20/29 (68%), Positives = 21/29 (72%)

Query: 1748 LNQQQQQQQQQQQQQQQQQQQQQQQQQQQ 1776
            L Q   Q +   QQQQQQQQQQQQQQQQQ
Sbjct: 448  LQQLHLQHRHPHQQQQQQQQQQQQQQQQQ 476



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 20/47 (42%), Positives = 25/47 (53%)

Query: 1741 EESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEH 1787
            ++   +   QQQQQQQQQQQQQQQQQQ         +  A     +H
Sbjct: 460  QQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQH 506



 Score = 32.3 bits (72), Expect = 4.3
 Identities = 23/73 (31%), Positives = 30/73 (41%), Gaps = 21/73 (28%)

Query: 1741 EESTARNLNQQQQQQQQQQQQ---------------------QQQQQQQQQQQQQQQVAA 1779
            ++   +   QQQQQQQQQQQQ                      QQQQ  QQQ     V  
Sbjct: 466  QQQQQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQMLQQQFLMHSVYQ 525

Query: 1780 AAGAATEHPPGSP 1792
               +A+++P   P
Sbjct: 526  PQPSASQYPTMMP 538


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.129    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,158,181
Number of Sequences: 37866
Number of extensions: 4018091
Number of successful extensions: 37206
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 335
Number of HSP's successfully gapped in prelim test: 468
Number of HSP's that attempted gapping in prelim test: 21760
Number of HSP's gapped (non-prelim): 8096
length of query: 1810
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1693
effective length of database: 13,817,196
effective search space: 23392512828
effective search space used: 23392512828
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.