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Search of human proteins with 88952907
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|88952907 PREDICTED: Beclin-1-like protein 1 [Homo sapiens]
(431 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|88952907 PREDICTED: Beclin-1-like protein 1 [Homo sapiens] 862 0.0
gi|88943925 PREDICTED: Beclin-1-like protein 1 [Homo sapiens] 862 0.0
gi|239753084 PREDICTED: Beclin-1-like protein 1 [Homo sapiens] 860 0.0
gi|4502395 beclin 1 [Homo sapiens] 464 e-131
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 41 0.002
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 41 0.002
gi|222418793 EF-hand calcium binding domain 4B isoform b [Homo s... 40 0.004
gi|222418791 EF-hand calcium binding domain 4B isoform a [Homo s... 40 0.004
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 40 0.005
gi|110611218 ribosome binding protein 1 [Homo sapiens] 39 0.007
gi|110611220 ribosome binding protein 1 [Homo sapiens] 39 0.007
gi|205277396 dynactin 1 isoform 4 [Homo sapiens] 39 0.009
gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 39 0.009
gi|13259508 dynactin 1 isoform 2 [Homo sapiens] 39 0.009
gi|13259510 dynactin 1 isoform 1 [Homo sapiens] 39 0.009
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 39 0.009
gi|29171755 PTPRF interacting protein alpha 2 [Homo sapiens] 39 0.009
gi|58530840 desmoplakin isoform I [Homo sapiens] 39 0.012
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 39 0.012
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 39 0.012
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 39 0.012
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 39 0.012
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 39 0.012
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 39 0.012
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 39 0.012
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 39 0.012
gi|190194355 p90 autoantigen [Homo sapiens] 38 0.016
gi|194353964 coiled-coil domain containing 157 [Homo sapiens] 38 0.016
gi|56550043 sarcolemma associated protein [Homo sapiens] 38 0.016
gi|122937382 Fas (TNFRSF6) binding factor 1 [Homo sapiens] 38 0.020
>gi|88952907 PREDICTED: Beclin-1-like protein 1 [Homo sapiens]
Length = 431
Score = 862 bits (2227), Expect = 0.0
Identities = 431/431 (100%), Positives = 431/431 (100%)
Query: 1 MSSIRFLCQRCHQALKLSGSSESRSLPAAPAPTSGQAEPGDTREPGVTTREVTDAEEQQD 60
MSSIRFLCQRCHQALKLSGSSESRSLPAAPAPTSGQAEPGDTREPGVTTREVTDAEEQQD
Sbjct: 1 MSSIRFLCQRCHQALKLSGSSESRSLPAAPAPTSGQAEPGDTREPGVTTREVTDAEEQQD 60
Query: 61 GASSRSPPGDGSVSKGHANIFTLLGELGAMHMLSSIQKAAGDIFDIVSGQAVVDHPLCEE 120
GASSRSPPGDGSVSKGHANIFTLLGELGAMHMLSSIQKAAGDIFDIVSGQAVVDHPLCEE
Sbjct: 61 GASSRSPPGDGSVSKGHANIFTLLGELGAMHMLSSIQKAAGDIFDIVSGQAVVDHPLCEE 120
Query: 121 CTDSLLEQLDIQLALTEADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQEL 180
CTDSLLEQLDIQLALTEADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQEL
Sbjct: 121 CTDSLLEQLDIQLALTEADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQEL 180
Query: 181 EDVDRNNARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYAR 240
EDVDRNNARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYAR
Sbjct: 181 EDVDRNNARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYAR 240
Query: 241 VQRDRLKEINCFTATFEIWVEGPLGVINNFRLGRLPTVRVGWNEINTAWGQAALLLLTLA 300
VQRDRLKEINCFTATFEIWVEGPLGVINNFRLGRLPTVRVGWNEINTAWGQAALLLLTLA
Sbjct: 241 VQRDRLKEINCFTATFEIWVEGPLGVINNFRLGRLPTVRVGWNEINTAWGQAALLLLTLA 300
Query: 301 NTIGLQFQRYRLIPCGNHSYLKSLTDDRTELPLFCYGGQDVFLNNKYDRAMVAFLDCMQQ 360
NTIGLQFQRYRLIPCGNHSYLKSLTDDRTELPLFCYGGQDVFLNNKYDRAMVAFLDCMQQ
Sbjct: 301 NTIGLQFQRYRLIPCGNHSYLKSLTDDRTELPLFCYGGQDVFLNNKYDRAMVAFLDCMQQ 360
Query: 361 FKEEAEKGELGLSLPYGIQVETGLMEDVGGRGECYSIRTHLNTQELWTKALKFMLINFKW 420
FKEEAEKGELGLSLPYGIQVETGLMEDVGGRGECYSIRTHLNTQELWTKALKFMLINFKW
Sbjct: 361 FKEEAEKGELGLSLPYGIQVETGLMEDVGGRGECYSIRTHLNTQELWTKALKFMLINFKW 420
Query: 421 SLIWVASRYQK 431
SLIWVASRYQK
Sbjct: 421 SLIWVASRYQK 431
>gi|88943925 PREDICTED: Beclin-1-like protein 1 [Homo sapiens]
Length = 431
Score = 862 bits (2227), Expect = 0.0
Identities = 431/431 (100%), Positives = 431/431 (100%)
Query: 1 MSSIRFLCQRCHQALKLSGSSESRSLPAAPAPTSGQAEPGDTREPGVTTREVTDAEEQQD 60
MSSIRFLCQRCHQALKLSGSSESRSLPAAPAPTSGQAEPGDTREPGVTTREVTDAEEQQD
Sbjct: 1 MSSIRFLCQRCHQALKLSGSSESRSLPAAPAPTSGQAEPGDTREPGVTTREVTDAEEQQD 60
Query: 61 GASSRSPPGDGSVSKGHANIFTLLGELGAMHMLSSIQKAAGDIFDIVSGQAVVDHPLCEE 120
GASSRSPPGDGSVSKGHANIFTLLGELGAMHMLSSIQKAAGDIFDIVSGQAVVDHPLCEE
Sbjct: 61 GASSRSPPGDGSVSKGHANIFTLLGELGAMHMLSSIQKAAGDIFDIVSGQAVVDHPLCEE 120
Query: 121 CTDSLLEQLDIQLALTEADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQEL 180
CTDSLLEQLDIQLALTEADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQEL
Sbjct: 121 CTDSLLEQLDIQLALTEADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQEL 180
Query: 181 EDVDRNNARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYAR 240
EDVDRNNARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYAR
Sbjct: 181 EDVDRNNARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYAR 240
Query: 241 VQRDRLKEINCFTATFEIWVEGPLGVINNFRLGRLPTVRVGWNEINTAWGQAALLLLTLA 300
VQRDRLKEINCFTATFEIWVEGPLGVINNFRLGRLPTVRVGWNEINTAWGQAALLLLTLA
Sbjct: 241 VQRDRLKEINCFTATFEIWVEGPLGVINNFRLGRLPTVRVGWNEINTAWGQAALLLLTLA 300
Query: 301 NTIGLQFQRYRLIPCGNHSYLKSLTDDRTELPLFCYGGQDVFLNNKYDRAMVAFLDCMQQ 360
NTIGLQFQRYRLIPCGNHSYLKSLTDDRTELPLFCYGGQDVFLNNKYDRAMVAFLDCMQQ
Sbjct: 301 NTIGLQFQRYRLIPCGNHSYLKSLTDDRTELPLFCYGGQDVFLNNKYDRAMVAFLDCMQQ 360
Query: 361 FKEEAEKGELGLSLPYGIQVETGLMEDVGGRGECYSIRTHLNTQELWTKALKFMLINFKW 420
FKEEAEKGELGLSLPYGIQVETGLMEDVGGRGECYSIRTHLNTQELWTKALKFMLINFKW
Sbjct: 361 FKEEAEKGELGLSLPYGIQVETGLMEDVGGRGECYSIRTHLNTQELWTKALKFMLINFKW 420
Query: 421 SLIWVASRYQK 431
SLIWVASRYQK
Sbjct: 421 SLIWVASRYQK 431
>gi|239753084 PREDICTED: Beclin-1-like protein 1 [Homo sapiens]
Length = 431
Score = 860 bits (2222), Expect = 0.0
Identities = 430/431 (99%), Positives = 430/431 (99%)
Query: 1 MSSIRFLCQRCHQALKLSGSSESRSLPAAPAPTSGQAEPGDTREPGVTTREVTDAEEQQD 60
MSSIRFLCQRCHQALKLSGSSESRSLPAAPAPTSGQAEPGDTREPGVTTREVTDAEEQQD
Sbjct: 1 MSSIRFLCQRCHQALKLSGSSESRSLPAAPAPTSGQAEPGDTREPGVTTREVTDAEEQQD 60
Query: 61 GASSRSPPGDGSVSKGHANIFTLLGELGAMHMLSSIQKAAGDIFDIVSGQAVVDHPLCEE 120
GASSRSPPGDGSVSKGHANIFTLLGELGAMHMLSSIQK AGDIFDIVSGQAVVDHPLCEE
Sbjct: 61 GASSRSPPGDGSVSKGHANIFTLLGELGAMHMLSSIQKXAGDIFDIVSGQAVVDHPLCEE 120
Query: 121 CTDSLLEQLDIQLALTEADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQEL 180
CTDSLLEQLDIQLALTEADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQEL
Sbjct: 121 CTDSLLEQLDIQLALTEADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQEL 180
Query: 181 EDVDRNNARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYAR 240
EDVDRNNARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYAR
Sbjct: 181 EDVDRNNARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYAR 240
Query: 241 VQRDRLKEINCFTATFEIWVEGPLGVINNFRLGRLPTVRVGWNEINTAWGQAALLLLTLA 300
VQRDRLKEINCFTATFEIWVEGPLGVINNFRLGRLPTVRVGWNEINTAWGQAALLLLTLA
Sbjct: 241 VQRDRLKEINCFTATFEIWVEGPLGVINNFRLGRLPTVRVGWNEINTAWGQAALLLLTLA 300
Query: 301 NTIGLQFQRYRLIPCGNHSYLKSLTDDRTELPLFCYGGQDVFLNNKYDRAMVAFLDCMQQ 360
NTIGLQFQRYRLIPCGNHSYLKSLTDDRTELPLFCYGGQDVFLNNKYDRAMVAFLDCMQQ
Sbjct: 301 NTIGLQFQRYRLIPCGNHSYLKSLTDDRTELPLFCYGGQDVFLNNKYDRAMVAFLDCMQQ 360
Query: 361 FKEEAEKGELGLSLPYGIQVETGLMEDVGGRGECYSIRTHLNTQELWTKALKFMLINFKW 420
FKEEAEKGELGLSLPYGIQVETGLMEDVGGRGECYSIRTHLNTQELWTKALKFMLINFKW
Sbjct: 361 FKEEAEKGELGLSLPYGIQVETGLMEDVGGRGECYSIRTHLNTQELWTKALKFMLINFKW 420
Query: 421 SLIWVASRYQK 431
SLIWVASRYQK
Sbjct: 421 SLIWVASRYQK 431
>gi|4502395 beclin 1 [Homo sapiens]
Length = 450
Score = 464 bits (1193), Expect = e-131
Identities = 244/435 (56%), Positives = 300/435 (68%), Gaps = 10/435 (2%)
Query: 4 IRFLCQRCHQALKLSGSSESRSLPA-----APAPTSGQAEPGDTREPGVTTREVTDAEE- 57
+ F+CQRC Q LKL S + AP T+ QA+PG+T+E + E E
Sbjct: 14 VSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEETNSGEEPFIETP 73
Query: 58 QQDGASSRSPPGDGSVSKGHANIFTLLGEL---GAMHMLSSIQKAAGDIFDIVSGQAVVD 114
+QDG S R P +S AN FTL+GE G M LS K GD+FDI+SGQ VD
Sbjct: 74 RQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDVD 133
Query: 115 HPLCEECTDSLLEQLDIQLALTEADSQNYQRCLETGELATSEDEAAALRAELRDLELEEA 174
HPLCEECTD+LL+QLD QL +TE + QNY+RCLE E +ED++ L+ EL++L LEE
Sbjct: 134 HPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILE-QMNEDDSEQLQMELKELALEEE 192
Query: 175 RLVQELEDVDRNNARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVEN 234
RL+QELEDV++N A +L+ QAEA LDQ+E Q+ R+YS KRQQLEL D+L +VEN
Sbjct: 193 RLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVEN 252
Query: 235 QLQYARVQRDRLKEINCFTATFEIWVEGPLGVINNFRLGRLPTVRVGWNEINTAWGQAAL 294
Q++YA+ Q D+LK+ N F ATF IW G G INNFRLGRLP+V V WNEIN AWGQ L
Sbjct: 253 QMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVL 312
Query: 295 LLLTLANTIGLQFQRYRLIPCGNHSYLKSLTDDRTELPLFCYGGQDVFLNNKYDRAMVAF 354
LL LAN +GL+FQRYRL+P GNHSYL+SLTD ELPL+C GG F +NK+D AMVAF
Sbjct: 313 LLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWDNKFDHAMVAF 372
Query: 355 LDCMQQFKEEAEKGELGLSLPYGIQVETGLMEDVGGRGECYSIRTHLNTQELWTKALKFM 414
LDC+QQFKEE EKGE LPY + VE G +ED GG G YSI+T N++E WTKALKFM
Sbjct: 373 LDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQWTKALKFM 432
Query: 415 LINFKWSLIWVASRY 429
L N KW L WV+S++
Sbjct: 433 LTNLKWGLAWVSSQF 447
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/124 (25%), Positives = 60/124 (48%), Gaps = 9/124 (7%)
Query: 127 EQLDIQLALTEADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDVDRN 186
E+L++ + ++Q Q+ LE S + L +EL+DLE+E L + LE++ +
Sbjct: 752 ERLEVSYQGLDIENQRLQKTLEN-----SNKKIQQLESELQDLEMENQTLQKNLEELKIS 806
Query: 187 NARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDRL 246
+ R L+ + E L+Q+ Q +D L+++ L Q + L+ V+ L
Sbjct: 807 SKR----LEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNL 862
Query: 247 KEIN 250
++ N
Sbjct: 863 EKEN 866
Score = 38.5 bits (88), Expect = 0.012
Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 4/102 (3%)
Query: 141 QNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQAAQAE 200
Q+ +R +++ + ED E ++ E ++ L +V+RNNA A+ QA + +
Sbjct: 1011 QDEERMVQSSPPISGEDNK--WERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQ 1068
Query: 201 AAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQ 242
+L+ Q AL+RQ + L +Q N Q Q A++Q
Sbjct: 1069 LKQLETQNNNLQAQILALQRQTVSLQEQ--NTTLQTQNAKLQ 1108
Score = 35.4 bits (80), Expect = 0.10
Identities = 37/139 (26%), Positives = 66/139 (47%), Gaps = 21/139 (15%)
Query: 127 EQLDIQLALTEADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDV--D 184
+ L ++LA +A + ++ EL ++ + EL +E+E RL QE ++ D
Sbjct: 247 QHLSVELADAKAKIRRLRQ-----ELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSD 301
Query: 185 RNNARAAAD-LQAAQAEAAELDQQERQ--HYRD-------YSA----LKRQQLELLDQLG 230
+AR D L A + +A +D+ E + Y++ Y A LK LL+
Sbjct: 302 ARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKT 361
Query: 231 NVENQLQYARVQRDRLKEI 249
+E+QL+ R + D+L E+
Sbjct: 362 MLEDQLEGTRARSDKLHEL 380
Score = 29.6 bits (65), Expect = 5.5
Identities = 23/98 (23%), Positives = 44/98 (44%), Gaps = 2/98 (2%)
Query: 152 LATSEDEAAALRAELRDLELEEARLVQELEDVDRN--NARAAADLQAAQAEAAELDQQER 209
L E++ AAL A L + +L QEL+ V +N + D + + + ++
Sbjct: 969 LEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDN 1028
Query: 210 QHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDRLK 247
+ R+ R+ L++ D+L VE + ++ LK
Sbjct: 1029 KWERESQETTRELLKVKDRLIEVERNNATLQAEKQALK 1066
Score = 29.3 bits (64), Expect = 7.2
Identities = 22/111 (19%), Positives = 56/111 (50%), Gaps = 3/111 (2%)
Query: 136 TEADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQ 195
T +QN Q ++ L E+E ++ E DL+ L+++ E ++ + R A++ +
Sbjct: 1119 TSLMNQNAQLLIQQSSL---ENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYE 1175
Query: 196 AAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDRL 246
+ ++ L + ++ L+ + +LL Q G +E+ + +V+++++
Sbjct: 1176 SLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKM 1226
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/124 (25%), Positives = 60/124 (48%), Gaps = 9/124 (7%)
Query: 127 EQLDIQLALTEADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDVDRN 186
E+L++ + ++Q Q+ LE S + L +EL+DLE+E L + LE++ +
Sbjct: 752 ERLEVSYQGLDIENQRLQKTLEN-----SNKKIQQLESELQDLEMENQTLQKNLEELKIS 806
Query: 187 NARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDRL 246
+ R L+ + E L+Q+ Q +D L+++ L Q + L+ V+ L
Sbjct: 807 SKR----LEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNL 862
Query: 247 KEIN 250
++ N
Sbjct: 863 EKEN 866
Score = 38.5 bits (88), Expect = 0.012
Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 4/102 (3%)
Query: 141 QNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQAAQAE 200
Q+ +R +++ + ED E ++ E ++ L +V+RNNA A+ QA + +
Sbjct: 1010 QDEERMVQSSPPISGEDNK--WERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQ 1067
Query: 201 AAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQ 242
+L+ Q AL+RQ + L +Q N Q Q A++Q
Sbjct: 1068 LKQLETQNNNLQAQILALQRQTVSLQEQ--NTTLQTQNAKLQ 1107
Score = 35.4 bits (80), Expect = 0.10
Identities = 37/139 (26%), Positives = 66/139 (47%), Gaps = 21/139 (15%)
Query: 127 EQLDIQLALTEADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDV--D 184
+ L ++LA +A + ++ EL ++ + EL +E+E RL QE ++ D
Sbjct: 247 QHLSVELADAKAKIRRLRQ-----ELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSD 301
Query: 185 RNNARAAAD-LQAAQAEAAELDQQERQ--HYRD-------YSA----LKRQQLELLDQLG 230
+AR D L A + +A +D+ E + Y++ Y A LK LL+
Sbjct: 302 ARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKT 361
Query: 231 NVENQLQYARVQRDRLKEI 249
+E+QL+ R + D+L E+
Sbjct: 362 MLEDQLEGTRARSDKLHEL 380
Score = 30.0 bits (66), Expect = 4.2
Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 13/131 (9%)
Query: 119 EECTDSLLEQLDIQLALTEADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQ 178
E+ TD + L+ +L T S L E++ AAL A L + +L Q
Sbjct: 946 EQSTDDRYKLLESKLESTLKKS-----------LEIKEEKIAALEARLEESTNYNQQLRQ 994
Query: 179 ELEDVDRN--NARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQL 236
EL+ V +N + D + + + ++ + R+ R+ L++ D+L VE
Sbjct: 995 ELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNN 1054
Query: 237 QYARVQRDRLK 247
+ ++ LK
Sbjct: 1055 ATLQAEKQALK 1065
Score = 29.3 bits (64), Expect = 7.2
Identities = 22/111 (19%), Positives = 56/111 (50%), Gaps = 3/111 (2%)
Query: 136 TEADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQ 195
T +QN Q ++ L E+E ++ E DL+ L+++ E ++ + R A++ +
Sbjct: 1118 TSLMNQNAQLLIQQSSL---ENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYE 1174
Query: 196 AAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDRL 246
+ ++ L + ++ L+ + +LL Q G +E+ + +V+++++
Sbjct: 1175 SLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKM 1225
>gi|222418793 EF-hand calcium binding domain 4B isoform b [Homo
sapiens]
Length = 462
Score = 40.0 bits (92), Expect = 0.004
Identities = 31/102 (30%), Positives = 51/102 (50%), Gaps = 2/102 (1%)
Query: 144 QRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQAAQAEAAE 203
Q+ LE G+ + +AE L+L L +ELE A L++ Q EA +
Sbjct: 284 QKRLE-GQCTALHHDKHETKAENTKLKLTNQELARELERTSWELQDAQQQLESLQQEACK 342
Query: 204 LDQQ-ERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRD 244
L Q+ E + YR +L+R++ LL QL + + ++ R +RD
Sbjct: 343 LHQEKEMEVYRVTESLQREKAGLLKQLDFLRERNKHLRDERD 384
>gi|222418791 EF-hand calcium binding domain 4B isoform a [Homo
sapiens]
Length = 731
Score = 40.0 bits (92), Expect = 0.004
Identities = 31/102 (30%), Positives = 51/102 (50%), Gaps = 2/102 (1%)
Query: 144 QRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQAAQAEAAE 203
Q+ LE G+ + +AE L+L L +ELE A L++ Q EA +
Sbjct: 284 QKRLE-GQCTALHHDKHETKAENTKLKLTNQELARELERTSWELQDAQQQLESLQQEACK 342
Query: 204 LDQQ-ERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRD 244
L Q+ E + YR +L+R++ LL QL + + ++ R +RD
Sbjct: 343 LHQEKEMEVYRVTESLQREKAGLLKQLDFLRERNKHLRDERD 384
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 39.7 bits (91), Expect = 0.005
Identities = 28/117 (23%), Positives = 60/117 (51%), Gaps = 2/117 (1%)
Query: 133 LALTEADSQNYQR-CLETG-ELATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARA 190
L TE+D++ +R ET L ++ + +L+A+ +DLE + + + L+++++ A
Sbjct: 1470 LLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAK 1529
Query: 191 AADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDRLK 247
+D Q + +L ++ ++ +D +R + L L E LQ R + ++LK
Sbjct: 1530 DSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLK 1586
Score = 38.1 bits (87), Expect = 0.016
Identities = 23/64 (35%), Positives = 32/64 (50%)
Query: 147 LETGELATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQAAQAEAAELDQ 206
L T EL ++D+ +L + + E A +QE E R A+AA DL A+AE L
Sbjct: 989 LATAELTIAKDQLKSLHGTVMKINQERAEELQEAERFSRKAAQAARDLTRAEAEIELLQN 1048
Query: 207 QERQ 210
RQ
Sbjct: 1049 LLRQ 1052
Score = 36.6 bits (83), Expect = 0.045
Identities = 29/133 (21%), Positives = 60/133 (45%), Gaps = 15/133 (11%)
Query: 130 DIQLALTEADSQNYQRCLETGELATSEDEAAALRAEL---------------RDLELEEA 174
D+Q AL +++ ++C E+ + +E + + EL +++E EE
Sbjct: 1623 DLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEE 1682
Query: 175 RLVQELEDVDRNNARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVEN 234
L L + ++ L Q E EL + QH + S L++ Q+ +L++ +EN
Sbjct: 1683 NLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELEN 1742
Query: 235 QLQYARVQRDRLK 247
Q ++ Q+ ++
Sbjct: 1743 LQQISQQQKGEIE 1755
Score = 36.6 bits (83), Expect = 0.045
Identities = 30/112 (26%), Positives = 49/112 (43%), Gaps = 11/112 (9%)
Query: 118 CEECTDSLLEQLDIQLALTEADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLV 177
C EC E L + + E +R L A +E+ + ++ L LEL +L
Sbjct: 1781 CVECLSKEKEDLQEKCDIWEKKLAQTKRVL-----AAAEENSKMEQSNLEKLELNVRKLQ 1835
Query: 178 QELEDVDRNNARAAADLQAAQ------AEAAELDQQERQHYRDYSALKRQQL 223
QEL+ ++R+ D+ A Q EA Q+E + +D+ L +Q L
Sbjct: 1836 QELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDL 1887
Score = 36.2 bits (82), Expect = 0.059
Identities = 32/135 (23%), Positives = 65/135 (48%), Gaps = 5/135 (3%)
Query: 119 EECTDSLLEQLDIQLALTEADSQNYQRCLETGE--LATSEDEAAALRAELRDLELEEARL 176
EE D + + Q+A EA ++ + + + L T + +A + E R L E+ L
Sbjct: 590 EEIKDLEEQLTEGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKETL 649
Query: 177 VQELEDVDRNNAR---AAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVE 233
+Q L +V++ + A D + + E AEL+ ++ + ++L++ Q +L +E
Sbjct: 650 LQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVNASLQQTQGDLSAYEAELE 709
Query: 234 NQLQYARVQRDRLKE 248
+L + ++LKE
Sbjct: 710 ARLNLRDAEANQLKE 724
Score = 35.4 bits (80), Expect = 0.10
Identities = 49/198 (24%), Positives = 84/198 (42%), Gaps = 39/198 (19%)
Query: 49 TREVTDAEEQQDGASSRSPPGDGSVSKGHANIFTLLGELGAMHMLSSIQKAAGDIFDIVS 108
T E+ D EEQ +G ++ A L G ++S +Q+ G I
Sbjct: 589 TEEIKDLEEQLT---------EGQIAANEALKKDLEG------VISGLQEYLGTI----K 629
Query: 109 GQAVVDHPLCEECTDSLLEQLDIQLALTEADSQNYQRCLETGELATSEDEAAALRAELRD 168
GQA C + D E+ + LTE + E +L +A +R EL +
Sbjct: 630 GQATQAQNECRKLRD---EKETLLQRLTEVEQ-------ERDQLEIVAMDAENMRKELAE 679
Query: 169 LELEEARLVQELEDVDRNNARAAADLQAAQAEAAELDQQERQHYRDYSALK-RQQLELLD 227
LE +QE +V+ + + DL A +AE + R + RD A + +++LE +
Sbjct: 680 LE----SALQEQHEVNASLQQTQGDLSAYEAEL-----EARLNLRDAEANQLKEELEKVT 730
Query: 228 QLGNVENQLQYARVQRDR 245
+L +E A ++++R
Sbjct: 731 RLTQLEQSALQAELEKER 748
>gi|110611218 ribosome binding protein 1 [Homo sapiens]
Length = 977
Score = 39.3 bits (90), Expect = 0.007
Identities = 39/164 (23%), Positives = 72/164 (43%), Gaps = 30/164 (18%)
Query: 110 QAVVDHPLCEECTDSLLEQLDIQLALTE------------ADSQNYQRCLETGELATSE- 156
Q H EE L+++ +L T+ A Q Q +L +SE
Sbjct: 435 QLQASHRESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQEQQQQMAELHSKLQSSEA 494
Query: 157 ------DEAAALRAELRDLELEEARLVQELEDVDR----NNARAAADLQAAQAEAAELDQ 206
+E + L +L++ E ++L + + ++ AR A D+QA+QAEA +
Sbjct: 495 EVRSKCEELSGLHGQLQEARAENSQLTERIRSIEALLEAGQARDAQDVQASQAEADQQQT 554
Query: 207 QERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDRLKEIN 250
+ ++ S L+++ +EL + VE Q +V+ + L+E N
Sbjct: 555 RLKELESQVSGLEKEAIELREA---VEQQ----KVKNNDLREKN 591
Score = 34.7 bits (78), Expect = 0.17
Identities = 31/107 (28%), Positives = 52/107 (48%), Gaps = 10/107 (9%)
Query: 144 QRCLETGE--LATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQAAQAE- 200
+R LE E LAT +++AA +++LR+L E + E A+ L A + E
Sbjct: 266 KRQLEEKEKLLATEQEDAAVAKSKLRELNKE---MAAEKAKAAAGEAKVKKQLVAREQEI 322
Query: 201 ---AAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRD 244
A + R+H ++ L+ + L +QL N N Q AR+Q++
Sbjct: 323 TAVQARMQASYREHVKEVQQLQGKIRTLQEQLENGPN-TQLARLQQE 368
>gi|110611220 ribosome binding protein 1 [Homo sapiens]
Length = 977
Score = 39.3 bits (90), Expect = 0.007
Identities = 39/164 (23%), Positives = 72/164 (43%), Gaps = 30/164 (18%)
Query: 110 QAVVDHPLCEECTDSLLEQLDIQLALTE------------ADSQNYQRCLETGELATSE- 156
Q H EE L+++ +L T+ A Q Q +L +SE
Sbjct: 435 QLQASHRESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQEQQQQMAELHSKLQSSEA 494
Query: 157 ------DEAAALRAELRDLELEEARLVQELEDVDR----NNARAAADLQAAQAEAAELDQ 206
+E + L +L++ E ++L + + ++ AR A D+QA+QAEA +
Sbjct: 495 EVRSKCEELSGLHGQLQEARAENSQLTERIRSIEALLEAGQARDAQDVQASQAEADQQQT 554
Query: 207 QERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDRLKEIN 250
+ ++ S L+++ +EL + VE Q +V+ + L+E N
Sbjct: 555 RLKELESQVSGLEKEAIELREA---VEQQ----KVKNNDLREKN 591
Score = 34.7 bits (78), Expect = 0.17
Identities = 31/107 (28%), Positives = 52/107 (48%), Gaps = 10/107 (9%)
Query: 144 QRCLETGE--LATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQAAQAE- 200
+R LE E LAT +++AA +++LR+L E + E A+ L A + E
Sbjct: 266 KRQLEEKEKLLATEQEDAAVAKSKLRELNKE---MAAEKAKAAAGEAKVKKQLVAREQEI 322
Query: 201 ---AAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRD 244
A + R+H ++ L+ + L +QL N N Q AR+Q++
Sbjct: 323 TAVQARMQASYREHVKEVQQLQGKIRTLQEQLENGPN-TQLARLQQE 368
>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
Length = 1139
Score = 38.9 bits (89), Expect = 0.009
Identities = 45/148 (30%), Positives = 65/148 (43%), Gaps = 27/148 (18%)
Query: 127 EQLDIQLALTEADSQNYQRCLETGELATSE--DEAAALRAELRDLELEEAR---LVQELE 181
+Q D+Q L EA + + LE E E D A A+ D E+ E R L QE+E
Sbjct: 134 QQADLQRRLKEARKEA-KEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVE 192
Query: 182 DVDRNNARAAADLQAAQAEAAE-----------LDQQERQH---------YRDYSALKRQ 221
+ DL+ +AE E L Q E Q+ RD S+ ++Q
Sbjct: 193 ALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQ 252
Query: 222 QLELLDQLGNVENQ-LQYARVQRDRLKE 248
+ L +L +NQ L+ R QR+RL+E
Sbjct: 253 EHVKLQKLMEKKNQELEVVRQQRERLQE 280
Score = 29.3 bits (64), Expect = 7.2
Identities = 26/103 (25%), Positives = 45/103 (43%), Gaps = 11/103 (10%)
Query: 152 LATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQAAQAEAAELDQQERQH 211
L + E LRA++RDLE ++LE + A A L+ + +L+Q +
Sbjct: 76 LPSPSKEEEGLRAQVRDLE-------EKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWK 128
Query: 212 YRDYSALKRQQLELLDQLGNVENQLQYARVQRDRLKEINCFTA 254
S ++ QQ +L +L + + A ++R E TA
Sbjct: 129 ----SKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTA 167
>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
Length = 1253
Score = 38.9 bits (89), Expect = 0.009
Identities = 45/148 (30%), Positives = 65/148 (43%), Gaps = 27/148 (18%)
Query: 127 EQLDIQLALTEADSQNYQRCLETGELATSE--DEAAALRAELRDLELEEAR---LVQELE 181
+Q D+Q L EA + + LE E E D A A+ D E+ E R L QE+E
Sbjct: 248 QQADLQRRLKEARKEA-KEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVE 306
Query: 182 DVDRNNARAAADLQAAQAEAAE-----------LDQQERQH---------YRDYSALKRQ 221
+ DL+ +AE E L Q E Q+ RD S+ ++Q
Sbjct: 307 ALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQ 366
Query: 222 QLELLDQLGNVENQ-LQYARVQRDRLKE 248
+ L +L +NQ L+ R QR+RL+E
Sbjct: 367 EHVKLQKLMEKKNQELEVVRQQRERLQE 394
Score = 29.3 bits (64), Expect = 7.2
Identities = 26/103 (25%), Positives = 45/103 (43%), Gaps = 11/103 (10%)
Query: 152 LATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQAAQAEAAELDQQERQH 211
L + E LRA++RDLE ++LE + A A L+ + +L+Q +
Sbjct: 190 LPSPSKEEEGLRAQVRDLE-------EKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWK 242
Query: 212 YRDYSALKRQQLELLDQLGNVENQLQYARVQRDRLKEINCFTA 254
S ++ QQ +L +L + + A ++R E TA
Sbjct: 243 ----SKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTA 281
>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
Length = 1144
Score = 38.9 bits (89), Expect = 0.009
Identities = 45/148 (30%), Positives = 65/148 (43%), Gaps = 27/148 (18%)
Query: 127 EQLDIQLALTEADSQNYQRCLETGELATSE--DEAAALRAELRDLELEEAR---LVQELE 181
+Q D+Q L EA + + LE E E D A A+ D E+ E R L QE+E
Sbjct: 134 QQADLQRRLKEARKEA-KEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVE 192
Query: 182 DVDRNNARAAADLQAAQAEAAE-----------LDQQERQH---------YRDYSALKRQ 221
+ DL+ +AE E L Q E Q+ RD S+ ++Q
Sbjct: 193 ALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQ 252
Query: 222 QLELLDQLGNVENQ-LQYARVQRDRLKE 248
+ L +L +NQ L+ R QR+RL+E
Sbjct: 253 EHVKLQKLMEKKNQELEVVRQQRERLQE 280
Score = 29.3 bits (64), Expect = 7.2
Identities = 26/103 (25%), Positives = 45/103 (43%), Gaps = 11/103 (10%)
Query: 152 LATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQAAQAEAAELDQQERQH 211
L + E LRA++RDLE ++LE + A A L+ + +L+Q +
Sbjct: 76 LPSPSKEEEGLRAQVRDLE-------EKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWK 128
Query: 212 YRDYSALKRQQLELLDQLGNVENQLQYARVQRDRLKEINCFTA 254
S ++ QQ +L +L + + A ++R E TA
Sbjct: 129 ----SKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTA 167
>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
Length = 1278
Score = 38.9 bits (89), Expect = 0.009
Identities = 45/148 (30%), Positives = 65/148 (43%), Gaps = 27/148 (18%)
Query: 127 EQLDIQLALTEADSQNYQRCLETGELATSE--DEAAALRAELRDLELEEAR---LVQELE 181
+Q D+Q L EA + + LE E E D A A+ D E+ E R L QE+E
Sbjct: 268 QQADLQRRLKEARKEA-KEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVE 326
Query: 182 DVDRNNARAAADLQAAQAEAAE-----------LDQQERQH---------YRDYSALKRQ 221
+ DL+ +AE E L Q E Q+ RD S+ ++Q
Sbjct: 327 ALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQ 386
Query: 222 QLELLDQLGNVENQ-LQYARVQRDRLKE 248
+ L +L +NQ L+ R QR+RL+E
Sbjct: 387 EHVKLQKLMEKKNQELEVVRQQRERLQE 414
Score = 29.3 bits (64), Expect = 7.2
Identities = 26/103 (25%), Positives = 45/103 (43%), Gaps = 11/103 (10%)
Query: 152 LATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQAAQAEAAELDQQERQH 211
L + E LRA++RDLE ++LE + A A L+ + +L+Q +
Sbjct: 210 LPSPSKEEEGLRAQVRDLE-------EKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWK 262
Query: 212 YRDYSALKRQQLELLDQLGNVENQLQYARVQRDRLKEINCFTA 254
S ++ QQ +L +L + + A ++R E TA
Sbjct: 263 ----SKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTA 301
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 38.9 bits (89), Expect = 0.009
Identities = 41/167 (24%), Positives = 71/167 (42%), Gaps = 29/167 (17%)
Query: 95 SIQKAAGDIFDIVSGQAVVDHPLCEECTDSLLEQLDIQLALTEADSQNYQRCLETGELAT 154
++++ D+ + ++ H L + LE+ DIQLAL EA E A
Sbjct: 1505 NLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEA------------EAAL 1552
Query: 155 SEDEAAALRAELR------DLELEEARLVQELEDVDRNNARAAADLQAA-------QAEA 201
+EA LR +L +++ + A +E+E + RN R +Q+A + EA
Sbjct: 1553 EHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEA 1612
Query: 202 AELDQQERQHYRD----YSALKRQQLELLDQLGNVENQLQYARVQRD 244
L ++ + S RQ E L L +V+ QL+ ++ D
Sbjct: 1613 IRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLD 1659
Score = 32.0 bits (71), Expect = 1.1
Identities = 30/132 (22%), Positives = 56/132 (42%), Gaps = 12/132 (9%)
Query: 137 EADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELE-------DVDRNNAR 189
+A + +Q+ L+ +L ED+ +L LE + L LE D++RN +
Sbjct: 998 KALQEAHQQALD--DLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRK 1055
Query: 190 AAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDRLKEI 249
DL+ AQ +L+ ++Q LK++ E VE++ + ++KE+
Sbjct: 1056 LEGDLKLAQESILDLENDKQQL---DERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKEL 1112
Query: 250 NCFTATFEIWVE 261
E +E
Sbjct: 1113 QARIEELEEEIE 1124
Score = 31.6 bits (70), Expect = 1.5
Identities = 30/105 (28%), Positives = 45/105 (42%), Gaps = 21/105 (20%)
Query: 152 LATSEDEAAALRAELRDLELEEARLVQELE----DVDRNNARAAA--------------- 192
L SE++ A+ A+ LE + RL E+E DV+R N+ AAA
Sbjct: 1398 LQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEW 1457
Query: 193 --DLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQ 235
+ +QAE ++ R + LK E LDQL V+ +
Sbjct: 1458 KTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRE 1502
Score = 30.8 bits (68), Expect = 2.5
Identities = 25/134 (18%), Positives = 56/134 (41%), Gaps = 11/134 (8%)
Query: 119 EECTDSLLEQLDIQLALTE----ADSQNYQRCLETGELATSEDEAAALRAELRDLELEEA 174
E C + + ++ + E A+ + T + EDE + L+ ++ DLEL A
Sbjct: 904 ERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLA 963
Query: 175 RLVQELEDVDRNNARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVEN 234
++ +E + +L A+L ++++ AL+ + LD L E+
Sbjct: 964 KVEKEKHATENKVKNLTEELSGLDETIAKLTREKK-------ALQEAHQQALDDLQAEED 1016
Query: 235 QLQYARVQRDRLKE 248
++ + +L++
Sbjct: 1017 KVNSLNKTKSKLEQ 1030
Score = 30.4 bits (67), Expect = 3.2
Identities = 55/257 (21%), Positives = 102/257 (39%), Gaps = 31/257 (12%)
Query: 9 QRCHQALKLSGSSESRSLPAAPAPTSGQAEPGDTREPGVTT--REVTDAEEQQDGASSRS 66
QR A +L SE L A TS Q E RE R++ +A Q + +
Sbjct: 1136 QRSDYARELEELSER--LEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVA-- 1191
Query: 67 PPGDGSVSKGHANIFTLLGEL--GAMHMLSSIQKAAGD----IFDIVSGQAVVD------ 114
++ K HA+ LGE + ++K + I D+ S V
Sbjct: 1192 -----ALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANL 1246
Query: 115 HPLCEECTDSLLEQL----DIQLALTEADSQNYQRCLETGELATSEDEAAALRAEL---- 166
+C D L E +IQ +L+E +Q + E GEL+ +E ++ ++L
Sbjct: 1247 EKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSK 1306
Query: 167 RDLELEEARLVQELEDVDRNNARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELL 226
+ + L ++LE+ ++ A LQ+++ + L +Q + + L+R +
Sbjct: 1307 QAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKAN 1366
Query: 227 DQLGNVENQLQYARVQR 243
++ + + +QR
Sbjct: 1367 SEVAQWRTKYETDAIQR 1383
>gi|29171755 PTPRF interacting protein alpha 2 [Homo sapiens]
Length = 1257
Score = 38.9 bits (89), Expect = 0.009
Identities = 31/142 (21%), Positives = 62/142 (43%), Gaps = 7/142 (4%)
Query: 109 GQAVVDHPLCEECTDSLLEQLDIQLALTEADSQNYQRCLETGELATSEDEAAALRAELRD 168
GQ V + L DS E I + QNY E+A ++ AAL + + +
Sbjct: 248 GQKVHEKRLSNGSIDSTDETSQIVELQELLEKQNY-------EMAQMKERLAALSSRVGE 300
Query: 169 LELEEARLVQELEDVDRNNARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQ 228
+E E ++L + N + D++ A A+ +++++ + Y + +R+ + D
Sbjct: 301 VEQEAETARKDLIKTEEMNTKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDM 360
Query: 229 LGNVENQLQYARVQRDRLKEIN 250
+EN+L +++E N
Sbjct: 361 NDKLENELANKEAILRQMEEKN 382
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 38.5 bits (88), Expect = 0.012
Identities = 31/133 (23%), Positives = 59/133 (44%), Gaps = 4/133 (3%)
Query: 119 EECTDSLLEQLDIQLALTEADSQNYQRCLET-GELATSEDEAAALRAELRDLELEEARLV 177
EE + LE D++ +EADS LE +L S + L+ + DL+ E L
Sbjct: 1722 EELRNLRLEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQRERENLR 1781
Query: 178 QELEDVDRNNARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELL---DQLGNVEN 234
QE+E + A+ +Q ++ + ++ Q+ L++ + L D+L ++
Sbjct: 1782 QEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKS 1841
Query: 235 QLQYARVQRDRLK 247
L+ + RL+
Sbjct: 1842 TLEAETRVKQRLE 1854
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 38.5 bits (88), Expect = 0.012
Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 10/93 (10%)
Query: 139 DSQNYQRCLETGELATSEDEAAALRAELRDLEL---------EEARLVQ-ELEDVDRNNA 188
D+Q +R ++ + A ++A+ R E EE R+V+ +LE +R
Sbjct: 1410 DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRG 1469
Query: 189 RAAADLQAAQAEAAELDQQERQHYRDYSALKRQ 221
A +LQA +A A E + Q+RQ + L+RQ
Sbjct: 1470 GAEGELQALRARAEEAEAQKRQAQEEAERLRRQ 1502
Score = 36.2 bits (82), Expect = 0.059
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 3/81 (3%)
Query: 151 ELATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQAAQAEAAELDQQERQ 210
E+A ++ + + + +E E RLV +E+ R A ++ Q E +L+QQ RQ
Sbjct: 2523 EVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQ 2582
Query: 211 H---YRDYSALKRQQLELLDQ 228
+ + R+QL+LL++
Sbjct: 2583 QEELLAEENQRLREQLQLLEE 2603
Score = 35.4 bits (80), Expect = 0.10
Identities = 29/117 (24%), Positives = 52/117 (44%), Gaps = 3/117 (2%)
Query: 134 ALTEADSQNYQRCLETGELATSEDEAAALRA-ELRDLELEEARLVQELEDVDRNNARAAA 192
A +A ++ ++ E ++ E AALR + D E+E+ + + E R A+
Sbjct: 2129 AQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK--KFAEQTLRQKAQVEQ 2186
Query: 193 DLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDRLKEI 249
+L + + E D Q+ + LK + E Q VE +L RVQ + L ++
Sbjct: 2187 ELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKL 2243
Score = 35.0 bits (79), Expect = 0.13
Identities = 29/109 (26%), Positives = 52/109 (47%), Gaps = 1/109 (0%)
Query: 137 EADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQA 196
E + QR L ELA + EAAA + ++LE E A++ E+E + + ARA + ++
Sbjct: 1721 ETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRS 1780
Query: 197 AQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDR 245
++ + + E +R+ A + +L L + + QL R R
Sbjct: 1781 TSEKSKQRLEAEAGRFREL-AEEAARLRALAEEAKRQRQLAEEDAARQR 1828
Score = 34.7 bits (78), Expect = 0.17
Identities = 36/118 (30%), Positives = 51/118 (43%), Gaps = 5/118 (4%)
Query: 129 LDIQLALTEADSQ-NYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDVDRNN 187
L+ Q L EA +Q Q E EL E R E ++ R +QE R +
Sbjct: 1369 LEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQS 1428
Query: 188 ARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLD-QLGNVENQLQYARVQRD 244
+ A +A QAEAAE + R + + R QLE + Q G E +LQ R + +
Sbjct: 1429 SEAEIQAKARQAEAAE---RSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAE 1483
Score = 33.5 bits (75), Expect = 0.38
Identities = 36/132 (27%), Positives = 67/132 (50%), Gaps = 17/132 (12%)
Query: 128 QLDIQLALTEADSQNYQRCLETGELA--TSEDEAAALRAELRDLELEEARLVQELEDVDR 185
+L+ Q L E D+ +R +E LA S ++AAA +AEL ELE R+ ED R
Sbjct: 1905 ELERQKGLVE-DTLRQRRQVEEEILALKASFEKAAAGKAEL---ELELGRIRSNAEDTLR 1960
Query: 186 NNARAAADLQAAQAEAAELDQQERQHYRDYSALK---------RQQLELLDQLGNVENQL 236
++ A+L+AA+ +++ R+ + K RQ+ L+++ ++ ++
Sbjct: 1961 --SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKV 2018
Query: 237 QYARVQRDRLKE 248
+ AR R+R ++
Sbjct: 2019 EEARRLRERAEQ 2030
Score = 29.6 bits (65), Expect = 5.5
Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 11/119 (9%)
Query: 135 LTEADSQNYQRCLETGELAT-----SEDEAAALRAELRDLELEEARLVQELEDVDRNNAR 189
L E Q R L+ + A +E++A A + ++ EL++ L QE +D+
Sbjct: 2024 LRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT-LQQEQSVLDQLRGE 2082
Query: 190 AAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDRLKE 248
A A +AA+ Q ER+ +A R+Q+E ++L + AR Q E
Sbjct: 2083 AEAARRAAEEAEEARVQAERE-----AAQSRRQVEEAERLKQSAEEQAQARAQAQAAAE 2136
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 38.5 bits (88), Expect = 0.012
Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 10/93 (10%)
Query: 139 DSQNYQRCLETGELATSEDEAAALRAELRDLEL---------EEARLVQ-ELEDVDRNNA 188
D+Q +R ++ + A ++A+ R E EE R+V+ +LE +R
Sbjct: 1414 DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRG 1473
Query: 189 RAAADLQAAQAEAAELDQQERQHYRDYSALKRQ 221
A +LQA +A A E + Q+RQ + L+RQ
Sbjct: 1474 GAEGELQALRARAEEAEAQKRQAQEEAERLRRQ 1506
Score = 36.2 bits (82), Expect = 0.059
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 3/81 (3%)
Query: 151 ELATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQAAQAEAAELDQQERQ 210
E+A ++ + + + +E E RLV +E+ R A ++ Q E +L+QQ RQ
Sbjct: 2527 EVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQ 2586
Query: 211 H---YRDYSALKRQQLELLDQ 228
+ + R+QL+LL++
Sbjct: 2587 QEELLAEENQRLREQLQLLEE 2607
Score = 35.4 bits (80), Expect = 0.10
Identities = 29/117 (24%), Positives = 52/117 (44%), Gaps = 3/117 (2%)
Query: 134 ALTEADSQNYQRCLETGELATSEDEAAALRA-ELRDLELEEARLVQELEDVDRNNARAAA 192
A +A ++ ++ E ++ E AALR + D E+E+ + + E R A+
Sbjct: 2133 AQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK--KFAEQTLRQKAQVEQ 2190
Query: 193 DLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDRLKEI 249
+L + + E D Q+ + LK + E Q VE +L RVQ + L ++
Sbjct: 2191 ELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKL 2247
Score = 35.0 bits (79), Expect = 0.13
Identities = 29/109 (26%), Positives = 52/109 (47%), Gaps = 1/109 (0%)
Query: 137 EADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQA 196
E + QR L ELA + EAAA + ++LE E A++ E+E + + ARA + ++
Sbjct: 1725 ETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRS 1784
Query: 197 AQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDR 245
++ + + E +R+ A + +L L + + QL R R
Sbjct: 1785 TSEKSKQRLEAEAGRFREL-AEEAARLRALAEEAKRQRQLAEEDAARQR 1832
Score = 34.7 bits (78), Expect = 0.17
Identities = 36/118 (30%), Positives = 51/118 (43%), Gaps = 5/118 (4%)
Query: 129 LDIQLALTEADSQ-NYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDVDRNN 187
L+ Q L EA +Q Q E EL E R E ++ R +QE R +
Sbjct: 1373 LEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQS 1432
Query: 188 ARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLD-QLGNVENQLQYARVQRD 244
+ A +A QAEAAE + R + + R QLE + Q G E +LQ R + +
Sbjct: 1433 SEAEIQAKARQAEAAE---RSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAE 1487
Score = 33.5 bits (75), Expect = 0.38
Identities = 36/132 (27%), Positives = 67/132 (50%), Gaps = 17/132 (12%)
Query: 128 QLDIQLALTEADSQNYQRCLETGELA--TSEDEAAALRAELRDLELEEARLVQELEDVDR 185
+L+ Q L E D+ +R +E LA S ++AAA +AEL ELE R+ ED R
Sbjct: 1909 ELERQKGLVE-DTLRQRRQVEEEILALKASFEKAAAGKAEL---ELELGRIRSNAEDTLR 1964
Query: 186 NNARAAADLQAAQAEAAELDQQERQHYRDYSALK---------RQQLELLDQLGNVENQL 236
++ A+L+AA+ +++ R+ + K RQ+ L+++ ++ ++
Sbjct: 1965 --SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKV 2022
Query: 237 QYARVQRDRLKE 248
+ AR R+R ++
Sbjct: 2023 EEARRLRERAEQ 2034
Score = 29.6 bits (65), Expect = 5.5
Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 11/119 (9%)
Query: 135 LTEADSQNYQRCLETGELAT-----SEDEAAALRAELRDLELEEARLVQELEDVDRNNAR 189
L E Q R L+ + A +E++A A + ++ EL++ L QE +D+
Sbjct: 2028 LRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT-LQQEQSVLDQLRGE 2086
Query: 190 AAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDRLKE 248
A A +AA+ Q ER+ +A R+Q+E ++L + AR Q E
Sbjct: 2087 AEAARRAAEEAEEARVQAERE-----AAQSRRQVEEAERLKQSAEEQAQARAQAQAAAE 2140
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 38.5 bits (88), Expect = 0.012
Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 10/93 (10%)
Query: 139 DSQNYQRCLETGELATSEDEAAALRAELRDLEL---------EEARLVQ-ELEDVDRNNA 188
D+Q +R ++ + A ++A+ R E EE R+V+ +LE +R
Sbjct: 1410 DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRG 1469
Query: 189 RAAADLQAAQAEAAELDQQERQHYRDYSALKRQ 221
A +LQA +A A E + Q+RQ + L+RQ
Sbjct: 1470 GAEGELQALRARAEEAEAQKRQAQEEAERLRRQ 1502
Score = 36.2 bits (82), Expect = 0.059
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 3/81 (3%)
Query: 151 ELATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQAAQAEAAELDQQERQ 210
E+A ++ + + + +E E RLV +E+ R A ++ Q E +L+QQ RQ
Sbjct: 2523 EVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQ 2582
Query: 211 H---YRDYSALKRQQLELLDQ 228
+ + R+QL+LL++
Sbjct: 2583 QEELLAEENQRLREQLQLLEE 2603
Score = 35.4 bits (80), Expect = 0.10
Identities = 29/117 (24%), Positives = 52/117 (44%), Gaps = 3/117 (2%)
Query: 134 ALTEADSQNYQRCLETGELATSEDEAAALRA-ELRDLELEEARLVQELEDVDRNNARAAA 192
A +A ++ ++ E ++ E AALR + D E+E+ + + E R A+
Sbjct: 2129 AQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK--KFAEQTLRQKAQVEQ 2186
Query: 193 DLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDRLKEI 249
+L + + E D Q+ + LK + E Q VE +L RVQ + L ++
Sbjct: 2187 ELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKL 2243
Score = 35.0 bits (79), Expect = 0.13
Identities = 29/109 (26%), Positives = 52/109 (47%), Gaps = 1/109 (0%)
Query: 137 EADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQA 196
E + QR L ELA + EAAA + ++LE E A++ E+E + + ARA + ++
Sbjct: 1721 ETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRS 1780
Query: 197 AQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDR 245
++ + + E +R+ A + +L L + + QL R R
Sbjct: 1781 TSEKSKQRLEAEAGRFREL-AEEAARLRALAEEAKRQRQLAEEDAARQR 1828
Score = 34.7 bits (78), Expect = 0.17
Identities = 36/118 (30%), Positives = 51/118 (43%), Gaps = 5/118 (4%)
Query: 129 LDIQLALTEADSQ-NYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDVDRNN 187
L+ Q L EA +Q Q E EL E R E ++ R +QE R +
Sbjct: 1369 LEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQS 1428
Query: 188 ARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLD-QLGNVENQLQYARVQRD 244
+ A +A QAEAAE + R + + R QLE + Q G E +LQ R + +
Sbjct: 1429 SEAEIQAKARQAEAAE---RSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAE 1483
Score = 33.5 bits (75), Expect = 0.38
Identities = 36/132 (27%), Positives = 67/132 (50%), Gaps = 17/132 (12%)
Query: 128 QLDIQLALTEADSQNYQRCLETGELA--TSEDEAAALRAELRDLELEEARLVQELEDVDR 185
+L+ Q L E D+ +R +E LA S ++AAA +AEL ELE R+ ED R
Sbjct: 1905 ELERQKGLVE-DTLRQRRQVEEEILALKASFEKAAAGKAEL---ELELGRIRSNAEDTLR 1960
Query: 186 NNARAAADLQAAQAEAAELDQQERQHYRDYSALK---------RQQLELLDQLGNVENQL 236
++ A+L+AA+ +++ R+ + K RQ+ L+++ ++ ++
Sbjct: 1961 --SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKV 2018
Query: 237 QYARVQRDRLKE 248
+ AR R+R ++
Sbjct: 2019 EEARRLRERAEQ 2030
Score = 29.6 bits (65), Expect = 5.5
Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 11/119 (9%)
Query: 135 LTEADSQNYQRCLETGELAT-----SEDEAAALRAELRDLELEEARLVQELEDVDRNNAR 189
L E Q R L+ + A +E++A A + ++ EL++ L QE +D+
Sbjct: 2024 LRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT-LQQEQSVLDQLRGE 2082
Query: 190 AAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDRLKE 248
A A +AA+ Q ER+ +A R+Q+E ++L + AR Q E
Sbjct: 2083 AEAARRAAEEAEEARVQAERE-----AAQSRRQVEEAERLKQSAEEQAQARAQAQAAAE 2136
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 38.5 bits (88), Expect = 0.012
Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 10/93 (10%)
Query: 139 DSQNYQRCLETGELATSEDEAAALRAELRDLEL---------EEARLVQ-ELEDVDRNNA 188
D+Q +R ++ + A ++A+ R E EE R+V+ +LE +R
Sbjct: 1378 DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRG 1437
Query: 189 RAAADLQAAQAEAAELDQQERQHYRDYSALKRQ 221
A +LQA +A A E + Q+RQ + L+RQ
Sbjct: 1438 GAEGELQALRARAEEAEAQKRQAQEEAERLRRQ 1470
Score = 36.2 bits (82), Expect = 0.059
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 3/81 (3%)
Query: 151 ELATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQAAQAEAAELDQQERQ 210
E+A ++ + + + +E E RLV +E+ R A ++ Q E +L+QQ RQ
Sbjct: 2491 EVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQ 2550
Query: 211 H---YRDYSALKRQQLELLDQ 228
+ + R+QL+LL++
Sbjct: 2551 QEELLAEENQRLREQLQLLEE 2571
Score = 35.4 bits (80), Expect = 0.10
Identities = 29/117 (24%), Positives = 52/117 (44%), Gaps = 3/117 (2%)
Query: 134 ALTEADSQNYQRCLETGELATSEDEAAALRA-ELRDLELEEARLVQELEDVDRNNARAAA 192
A +A ++ ++ E ++ E AALR + D E+E+ + + E R A+
Sbjct: 2097 AQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK--KFAEQTLRQKAQVEQ 2154
Query: 193 DLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDRLKEI 249
+L + + E D Q+ + LK + E Q VE +L RVQ + L ++
Sbjct: 2155 ELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKL 2211
Score = 35.0 bits (79), Expect = 0.13
Identities = 29/109 (26%), Positives = 52/109 (47%), Gaps = 1/109 (0%)
Query: 137 EADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQA 196
E + QR L ELA + EAAA + ++LE E A++ E+E + + ARA + ++
Sbjct: 1689 ETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRS 1748
Query: 197 AQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDR 245
++ + + E +R+ A + +L L + + QL R R
Sbjct: 1749 TSEKSKQRLEAEAGRFREL-AEEAARLRALAEEAKRQRQLAEEDAARQR 1796
Score = 34.7 bits (78), Expect = 0.17
Identities = 36/118 (30%), Positives = 51/118 (43%), Gaps = 5/118 (4%)
Query: 129 LDIQLALTEADSQ-NYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDVDRNN 187
L+ Q L EA +Q Q E EL E R E ++ R +QE R +
Sbjct: 1337 LEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQS 1396
Query: 188 ARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLD-QLGNVENQLQYARVQRD 244
+ A +A QAEAAE + R + + R QLE + Q G E +LQ R + +
Sbjct: 1397 SEAEIQAKARQAEAAE---RSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAE 1451
Score = 33.5 bits (75), Expect = 0.38
Identities = 36/132 (27%), Positives = 67/132 (50%), Gaps = 17/132 (12%)
Query: 128 QLDIQLALTEADSQNYQRCLETGELA--TSEDEAAALRAELRDLELEEARLVQELEDVDR 185
+L+ Q L E D+ +R +E LA S ++AAA +AEL ELE R+ ED R
Sbjct: 1873 ELERQKGLVE-DTLRQRRQVEEEILALKASFEKAAAGKAEL---ELELGRIRSNAEDTLR 1928
Query: 186 NNARAAADLQAAQAEAAELDQQERQHYRDYSALK---------RQQLELLDQLGNVENQL 236
++ A+L+AA+ +++ R+ + K RQ+ L+++ ++ ++
Sbjct: 1929 --SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKV 1986
Query: 237 QYARVQRDRLKE 248
+ AR R+R ++
Sbjct: 1987 EEARRLRERAEQ 1998
Score = 29.6 bits (65), Expect = 5.5
Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 11/119 (9%)
Query: 135 LTEADSQNYQRCLETGELAT-----SEDEAAALRAELRDLELEEARLVQELEDVDRNNAR 189
L E Q R L+ + A +E++A A + ++ EL++ L QE +D+
Sbjct: 1992 LRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT-LQQEQSVLDQLRGE 2050
Query: 190 AAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDRLKE 248
A A +AA+ Q ER+ +A R+Q+E ++L + AR Q E
Sbjct: 2051 AEAARRAAEEAEEARVQAERE-----AAQSRRQVEEAERLKQSAEEQAQARAQAQAAAE 2104
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 38.5 bits (88), Expect = 0.012
Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 10/93 (10%)
Query: 139 DSQNYQRCLETGELATSEDEAAALRAELRDLEL---------EEARLVQ-ELEDVDRNNA 188
D+Q +R ++ + A ++A+ R E EE R+V+ +LE +R
Sbjct: 1547 DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRG 1606
Query: 189 RAAADLQAAQAEAAELDQQERQHYRDYSALKRQ 221
A +LQA +A A E + Q+RQ + L+RQ
Sbjct: 1607 GAEGELQALRARAEEAEAQKRQAQEEAERLRRQ 1639
Score = 36.2 bits (82), Expect = 0.059
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 3/81 (3%)
Query: 151 ELATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQAAQAEAAELDQQERQ 210
E+A ++ + + + +E E RLV +E+ R A ++ Q E +L+QQ RQ
Sbjct: 2660 EVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQ 2719
Query: 211 H---YRDYSALKRQQLELLDQ 228
+ + R+QL+LL++
Sbjct: 2720 QEELLAEENQRLREQLQLLEE 2740
Score = 35.4 bits (80), Expect = 0.10
Identities = 29/117 (24%), Positives = 52/117 (44%), Gaps = 3/117 (2%)
Query: 134 ALTEADSQNYQRCLETGELATSEDEAAALRA-ELRDLELEEARLVQELEDVDRNNARAAA 192
A +A ++ ++ E ++ E AALR + D E+E+ + + E R A+
Sbjct: 2266 AQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK--KFAEQTLRQKAQVEQ 2323
Query: 193 DLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDRLKEI 249
+L + + E D Q+ + LK + E Q VE +L RVQ + L ++
Sbjct: 2324 ELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKL 2380
Score = 35.0 bits (79), Expect = 0.13
Identities = 29/109 (26%), Positives = 52/109 (47%), Gaps = 1/109 (0%)
Query: 137 EADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQA 196
E + QR L ELA + EAAA + ++LE E A++ E+E + + ARA + ++
Sbjct: 1858 ETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRS 1917
Query: 197 AQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDR 245
++ + + E +R+ A + +L L + + QL R R
Sbjct: 1918 TSEKSKQRLEAEAGRFREL-AEEAARLRALAEEAKRQRQLAEEDAARQR 1965
Score = 34.7 bits (78), Expect = 0.17
Identities = 36/118 (30%), Positives = 51/118 (43%), Gaps = 5/118 (4%)
Query: 129 LDIQLALTEADSQ-NYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDVDRNN 187
L+ Q L EA +Q Q E EL E R E ++ R +QE R +
Sbjct: 1506 LEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQS 1565
Query: 188 ARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLD-QLGNVENQLQYARVQRD 244
+ A +A QAEAAE + R + + R QLE + Q G E +LQ R + +
Sbjct: 1566 SEAEIQAKARQAEAAE---RSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAE 1620
Score = 33.5 bits (75), Expect = 0.38
Identities = 36/132 (27%), Positives = 67/132 (50%), Gaps = 17/132 (12%)
Query: 128 QLDIQLALTEADSQNYQRCLETGELA--TSEDEAAALRAELRDLELEEARLVQELEDVDR 185
+L+ Q L E D+ +R +E LA S ++AAA +AEL ELE R+ ED R
Sbjct: 2042 ELERQKGLVE-DTLRQRRQVEEEILALKASFEKAAAGKAEL---ELELGRIRSNAEDTLR 2097
Query: 186 NNARAAADLQAAQAEAAELDQQERQHYRDYSALK---------RQQLELLDQLGNVENQL 236
++ A+L+AA+ +++ R+ + K RQ+ L+++ ++ ++
Sbjct: 2098 --SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKV 2155
Query: 237 QYARVQRDRLKE 248
+ AR R+R ++
Sbjct: 2156 EEARRLRERAEQ 2167
Score = 29.6 bits (65), Expect = 5.5
Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 11/119 (9%)
Query: 135 LTEADSQNYQRCLETGELAT-----SEDEAAALRAELRDLELEEARLVQELEDVDRNNAR 189
L E Q R L+ + A +E++A A + ++ EL++ L QE +D+
Sbjct: 2161 LRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT-LQQEQSVLDQLRGE 2219
Query: 190 AAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDRLKE 248
A A +AA+ Q ER+ +A R+Q+E ++L + AR Q E
Sbjct: 2220 AEAARRAAEEAEEARVQAERE-----AAQSRRQVEEAERLKQSAEEQAQARAQAQAAAE 2273
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 38.5 bits (88), Expect = 0.012
Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 10/93 (10%)
Query: 139 DSQNYQRCLETGELATSEDEAAALRAELRDLEL---------EEARLVQ-ELEDVDRNNA 188
D+Q +R ++ + A ++A+ R E EE R+V+ +LE +R
Sbjct: 1388 DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRG 1447
Query: 189 RAAADLQAAQAEAAELDQQERQHYRDYSALKRQ 221
A +LQA +A A E + Q+RQ + L+RQ
Sbjct: 1448 GAEGELQALRARAEEAEAQKRQAQEEAERLRRQ 1480
Score = 36.2 bits (82), Expect = 0.059
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 3/81 (3%)
Query: 151 ELATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQAAQAEAAELDQQERQ 210
E+A ++ + + + +E E RLV +E+ R A ++ Q E +L+QQ RQ
Sbjct: 2501 EVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQ 2560
Query: 211 H---YRDYSALKRQQLELLDQ 228
+ + R+QL+LL++
Sbjct: 2561 QEELLAEENQRLREQLQLLEE 2581
Score = 35.4 bits (80), Expect = 0.10
Identities = 29/117 (24%), Positives = 52/117 (44%), Gaps = 3/117 (2%)
Query: 134 ALTEADSQNYQRCLETGELATSEDEAAALRA-ELRDLELEEARLVQELEDVDRNNARAAA 192
A +A ++ ++ E ++ E AALR + D E+E+ + + E R A+
Sbjct: 2107 AQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK--KFAEQTLRQKAQVEQ 2164
Query: 193 DLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDRLKEI 249
+L + + E D Q+ + LK + E Q VE +L RVQ + L ++
Sbjct: 2165 ELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKL 2221
Score = 35.0 bits (79), Expect = 0.13
Identities = 29/109 (26%), Positives = 52/109 (47%), Gaps = 1/109 (0%)
Query: 137 EADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQA 196
E + QR L ELA + EAAA + ++LE E A++ E+E + + ARA + ++
Sbjct: 1699 ETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRS 1758
Query: 197 AQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDR 245
++ + + E +R+ A + +L L + + QL R R
Sbjct: 1759 TSEKSKQRLEAEAGRFREL-AEEAARLRALAEEAKRQRQLAEEDAARQR 1806
Score = 34.7 bits (78), Expect = 0.17
Identities = 36/118 (30%), Positives = 51/118 (43%), Gaps = 5/118 (4%)
Query: 129 LDIQLALTEADSQ-NYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDVDRNN 187
L+ Q L EA +Q Q E EL E R E ++ R +QE R +
Sbjct: 1347 LEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQS 1406
Query: 188 ARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLD-QLGNVENQLQYARVQRD 244
+ A +A QAEAAE + R + + R QLE + Q G E +LQ R + +
Sbjct: 1407 SEAEIQAKARQAEAAE---RSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAE 1461
Score = 33.5 bits (75), Expect = 0.38
Identities = 36/132 (27%), Positives = 67/132 (50%), Gaps = 17/132 (12%)
Query: 128 QLDIQLALTEADSQNYQRCLETGELA--TSEDEAAALRAELRDLELEEARLVQELEDVDR 185
+L+ Q L E D+ +R +E LA S ++AAA +AEL ELE R+ ED R
Sbjct: 1883 ELERQKGLVE-DTLRQRRQVEEEILALKASFEKAAAGKAEL---ELELGRIRSNAEDTLR 1938
Query: 186 NNARAAADLQAAQAEAAELDQQERQHYRDYSALK---------RQQLELLDQLGNVENQL 236
++ A+L+AA+ +++ R+ + K RQ+ L+++ ++ ++
Sbjct: 1939 --SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKV 1996
Query: 237 QYARVQRDRLKE 248
+ AR R+R ++
Sbjct: 1997 EEARRLRERAEQ 2008
Score = 29.6 bits (65), Expect = 5.5
Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 11/119 (9%)
Query: 135 LTEADSQNYQRCLETGELAT-----SEDEAAALRAELRDLELEEARLVQELEDVDRNNAR 189
L E Q R L+ + A +E++A A + ++ EL++ L QE +D+
Sbjct: 2002 LRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT-LQQEQSVLDQLRGE 2060
Query: 190 AAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDRLKE 248
A A +AA+ Q ER+ +A R+Q+E ++L + AR Q E
Sbjct: 2061 AEAARRAAEEAEEARVQAERE-----AAQSRRQVEEAERLKQSAEEQAQARAQAQAAAE 2114
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 38.5 bits (88), Expect = 0.012
Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 10/93 (10%)
Query: 139 DSQNYQRCLETGELATSEDEAAALRAELRDLEL---------EEARLVQ-ELEDVDRNNA 188
D+Q +R ++ + A ++A+ R E EE R+V+ +LE +R
Sbjct: 1396 DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRG 1455
Query: 189 RAAADLQAAQAEAAELDQQERQHYRDYSALKRQ 221
A +LQA +A A E + Q+RQ + L+RQ
Sbjct: 1456 GAEGELQALRARAEEAEAQKRQAQEEAERLRRQ 1488
Score = 36.2 bits (82), Expect = 0.059
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 3/81 (3%)
Query: 151 ELATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQAAQAEAAELDQQERQ 210
E+A ++ + + + +E E RLV +E+ R A ++ Q E +L+QQ RQ
Sbjct: 2509 EVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQ 2568
Query: 211 H---YRDYSALKRQQLELLDQ 228
+ + R+QL+LL++
Sbjct: 2569 QEELLAEENQRLREQLQLLEE 2589
Score = 35.4 bits (80), Expect = 0.10
Identities = 29/117 (24%), Positives = 52/117 (44%), Gaps = 3/117 (2%)
Query: 134 ALTEADSQNYQRCLETGELATSEDEAAALRA-ELRDLELEEARLVQELEDVDRNNARAAA 192
A +A ++ ++ E ++ E AALR + D E+E+ + + E R A+
Sbjct: 2115 AQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK--KFAEQTLRQKAQVEQ 2172
Query: 193 DLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDRLKEI 249
+L + + E D Q+ + LK + E Q VE +L RVQ + L ++
Sbjct: 2173 ELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKL 2229
Score = 35.0 bits (79), Expect = 0.13
Identities = 29/109 (26%), Positives = 52/109 (47%), Gaps = 1/109 (0%)
Query: 137 EADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQA 196
E + QR L ELA + EAAA + ++LE E A++ E+E + + ARA + ++
Sbjct: 1707 ETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRS 1766
Query: 197 AQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDR 245
++ + + E +R+ A + +L L + + QL R R
Sbjct: 1767 TSEKSKQRLEAEAGRFREL-AEEAARLRALAEEAKRQRQLAEEDAARQR 1814
Score = 34.7 bits (78), Expect = 0.17
Identities = 36/118 (30%), Positives = 51/118 (43%), Gaps = 5/118 (4%)
Query: 129 LDIQLALTEADSQ-NYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDVDRNN 187
L+ Q L EA +Q Q E EL E R E ++ R +QE R +
Sbjct: 1355 LEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQS 1414
Query: 188 ARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLD-QLGNVENQLQYARVQRD 244
+ A +A QAEAAE + R + + R QLE + Q G E +LQ R + +
Sbjct: 1415 SEAEIQAKARQAEAAE---RSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAE 1469
Score = 33.5 bits (75), Expect = 0.38
Identities = 36/132 (27%), Positives = 67/132 (50%), Gaps = 17/132 (12%)
Query: 128 QLDIQLALTEADSQNYQRCLETGELA--TSEDEAAALRAELRDLELEEARLVQELEDVDR 185
+L+ Q L E D+ +R +E LA S ++AAA +AEL ELE R+ ED R
Sbjct: 1891 ELERQKGLVE-DTLRQRRQVEEEILALKASFEKAAAGKAEL---ELELGRIRSNAEDTLR 1946
Query: 186 NNARAAADLQAAQAEAAELDQQERQHYRDYSALK---------RQQLELLDQLGNVENQL 236
++ A+L+AA+ +++ R+ + K RQ+ L+++ ++ ++
Sbjct: 1947 --SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKV 2004
Query: 237 QYARVQRDRLKE 248
+ AR R+R ++
Sbjct: 2005 EEARRLRERAEQ 2016
Score = 29.6 bits (65), Expect = 5.5
Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 11/119 (9%)
Query: 135 LTEADSQNYQRCLETGELAT-----SEDEAAALRAELRDLELEEARLVQELEDVDRNNAR 189
L E Q R L+ + A +E++A A + ++ EL++ L QE +D+
Sbjct: 2010 LRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT-LQQEQSVLDQLRGE 2068
Query: 190 AAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDRLKE 248
A A +AA+ Q ER+ +A R+Q+E ++L + AR Q E
Sbjct: 2069 AEAARRAAEEAEEARVQAERE-----AAQSRRQVEEAERLKQSAEEQAQARAQAQAAAE 2122
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 38.5 bits (88), Expect = 0.012
Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 10/93 (10%)
Query: 139 DSQNYQRCLETGELATSEDEAAALRAELRDLEL---------EEARLVQ-ELEDVDRNNA 188
D+Q +R ++ + A ++A+ R E EE R+V+ +LE +R
Sbjct: 1437 DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRG 1496
Query: 189 RAAADLQAAQAEAAELDQQERQHYRDYSALKRQ 221
A +LQA +A A E + Q+RQ + L+RQ
Sbjct: 1497 GAEGELQALRARAEEAEAQKRQAQEEAERLRRQ 1529
Score = 36.2 bits (82), Expect = 0.059
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 3/81 (3%)
Query: 151 ELATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQAAQAEAAELDQQERQ 210
E+A ++ + + + +E E RLV +E+ R A ++ Q E +L+QQ RQ
Sbjct: 2550 EVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQ 2609
Query: 211 H---YRDYSALKRQQLELLDQ 228
+ + R+QL+LL++
Sbjct: 2610 QEELLAEENQRLREQLQLLEE 2630
Score = 35.4 bits (80), Expect = 0.10
Identities = 29/117 (24%), Positives = 52/117 (44%), Gaps = 3/117 (2%)
Query: 134 ALTEADSQNYQRCLETGELATSEDEAAALRA-ELRDLELEEARLVQELEDVDRNNARAAA 192
A +A ++ ++ E ++ E AALR + D E+E+ + + E R A+
Sbjct: 2156 AQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHK--KFAEQTLRQKAQVEQ 2213
Query: 193 DLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDRLKEI 249
+L + + E D Q+ + LK + E Q VE +L RVQ + L ++
Sbjct: 2214 ELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKL 2270
Score = 35.0 bits (79), Expect = 0.13
Identities = 29/109 (26%), Positives = 52/109 (47%), Gaps = 1/109 (0%)
Query: 137 EADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQA 196
E + QR L ELA + EAAA + ++LE E A++ E+E + + ARA + ++
Sbjct: 1748 ETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRS 1807
Query: 197 AQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDR 245
++ + + E +R+ A + +L L + + QL R R
Sbjct: 1808 TSEKSKQRLEAEAGRFREL-AEEAARLRALAEEAKRQRQLAEEDAARQR 1855
Score = 34.7 bits (78), Expect = 0.17
Identities = 36/118 (30%), Positives = 51/118 (43%), Gaps = 5/118 (4%)
Query: 129 LDIQLALTEADSQ-NYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDVDRNN 187
L+ Q L EA +Q Q E EL E R E ++ R +QE R +
Sbjct: 1396 LEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQS 1455
Query: 188 ARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLD-QLGNVENQLQYARVQRD 244
+ A +A QAEAAE + R + + R QLE + Q G E +LQ R + +
Sbjct: 1456 SEAEIQAKARQAEAAE---RSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAE 1510
Score = 33.5 bits (75), Expect = 0.38
Identities = 36/132 (27%), Positives = 67/132 (50%), Gaps = 17/132 (12%)
Query: 128 QLDIQLALTEADSQNYQRCLETGELA--TSEDEAAALRAELRDLELEEARLVQELEDVDR 185
+L+ Q L E D+ +R +E LA S ++AAA +AEL ELE R+ ED R
Sbjct: 1932 ELERQKGLVE-DTLRQRRQVEEEILALKASFEKAAAGKAEL---ELELGRIRSNAEDTLR 1987
Query: 186 NNARAAADLQAAQAEAAELDQQERQHYRDYSALK---------RQQLELLDQLGNVENQL 236
++ A+L+AA+ +++ R+ + K RQ+ L+++ ++ ++
Sbjct: 1988 --SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKV 2045
Query: 237 QYARVQRDRLKE 248
+ AR R+R ++
Sbjct: 2046 EEARRLRERAEQ 2057
Score = 29.6 bits (65), Expect = 5.5
Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 11/119 (9%)
Query: 135 LTEADSQNYQRCLETGELAT-----SEDEAAALRAELRDLELEEARLVQELEDVDRNNAR 189
L E Q R L+ + A +E++A A + ++ EL++ L QE +D+
Sbjct: 2051 LRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT-LQQEQSVLDQLRGE 2109
Query: 190 AAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDRLKE 248
A A +AA+ Q ER+ +A R+Q+E ++L + AR Q E
Sbjct: 2110 AEAARRAAEEAEEARVQAERE-----AAQSRRQVEEAERLKQSAEEQAQARAQAQAAAE 2163
>gi|190194355 p90 autoantigen [Homo sapiens]
Length = 905
Score = 38.1 bits (87), Expect = 0.016
Identities = 35/154 (22%), Positives = 67/154 (43%), Gaps = 15/154 (9%)
Query: 108 SGQAVVDHPLCEECTDSLLEQLDIQLALTEADSQNYQRCLETGELATSEDE--AAALRAE 165
SG V D +C+ +++ +++L+ + Q LET LA ++ + A R +
Sbjct: 606 SGMVVKDQ-ICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQ 664
Query: 166 LRDLELEEARLVQELEDVDRNNARAAADLQAAQAEAAELDQQERQHY-----------RD 214
E E L L +V+R N + L+A Q E +E Q + +H +
Sbjct: 665 RTQAETEARTLASMLREVERKNEELSVLLKAQQVE-SERAQSDIEHLFQHNRKLESVAEE 723
Query: 215 YSALKRQQLELLDQLGNVENQLQYARVQRDRLKE 248
+ L + +ELL + + E + + ++ D L +
Sbjct: 724 HEILTKSYMELLQRNESTEKKNKDLQITCDSLNK 757
>gi|194353964 coiled-coil domain containing 157 [Homo sapiens]
Length = 752
Score = 38.1 bits (87), Expect = 0.016
Identities = 23/112 (20%), Positives = 48/112 (42%)
Query: 128 QLDIQLALTEADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDVDRNN 187
+ +QL + + Q C + EL + ++ L+ ++ L+++L+ +D+
Sbjct: 406 EAQVQLLVGRLEGAGQQVCWASTELDKEKARVDSMVRHQESLQAKQRALLKQLDSLDQER 465
Query: 188 ARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYA 239
L A+A+ A +++Q + R Q ELL L + L+ A
Sbjct: 466 EELRGSLDEAEAQRARVEEQLQSEREQGQCQLRAQQELLQSLQREKQGLEQA 517
>gi|56550043 sarcolemma associated protein [Homo sapiens]
Length = 811
Score = 38.1 bits (87), Expect = 0.016
Identities = 23/79 (29%), Positives = 39/79 (49%)
Query: 157 DEAAALRAELRDLELEEARLVQELEDVDRNNARAAADLQAAQAEAAELDQQERQHYRDYS 216
+EA L+ EL L E L E + R N +++LQ + E +Q + D S
Sbjct: 633 EEATRLQGELEKLRKEWNALETECHSLKRENVLLSSELQRQEKELHNSQKQSLELTSDLS 692
Query: 217 ALKRQQLELLDQLGNVENQ 235
L+ + EL +Q+G+++ Q
Sbjct: 693 ILQMSRKELENQVGSLKEQ 711
Score = 33.5 bits (75), Expect = 0.38
Identities = 30/120 (25%), Positives = 47/120 (39%), Gaps = 11/120 (9%)
Query: 139 DSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELE-------DVDRNNARAA 191
D Q + GEL E AL E L+ E L EL+ + + +
Sbjct: 629 DQQREEATRLQGELEKLRKEWNALETECHSLKRENVLLSSELQRQEKELHNSQKQSLELT 688
Query: 192 ADLQAAQAEAAELDQQ----ERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQRDRLK 247
+DL Q EL+ Q + QH RD + LK + +Q +V+ + + + LK
Sbjct: 689 SDLSILQMSRKELENQVGSLKEQHLRDSADLKTLLSKAENQAKDVQKEYEKTQTVLSELK 748
>gi|122937382 Fas (TNFRSF6) binding factor 1 [Homo sapiens]
Length = 1133
Score = 37.7 bits (86), Expect = 0.020
Identities = 30/117 (25%), Positives = 53/117 (45%), Gaps = 18/117 (15%)
Query: 127 EQLDIQLALTEADSQNYQRCLETGELATSEDE---------AAALRAELRDLELEEARLV 177
EQ ++++ +E ++ Q E L E A ALR +LR E+E V
Sbjct: 924 EQAELKIRASELRAEEKQLAAERAALEQERQELRLEKERINATALRVKLRAEEVESMSKV 983
Query: 178 ---------QELEDVDRNNARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLEL 225
+ L + + A A LQA Q + L +QE+ ++++ +L +Q+L+L
Sbjct: 984 ASEKYEEGERALREAQQVQAEQQARLQAVQQQQERLRKQEQHMHQEHLSLAQQRLQL 1040
Score = 35.4 bits (80), Expect = 0.10
Identities = 33/122 (27%), Positives = 54/122 (44%), Gaps = 12/122 (9%)
Query: 124 SLLEQLDIQLALTEADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQELEDV 183
SL +Q L L E+ ++ + LET E LR E +L AR + + ++
Sbjct: 612 SLQQQHQADLELIESAHRSRIKVLETSYQQREE----RLRRENEELS---ARYLSQCQEA 664
Query: 184 DRNNARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYARVQR 243
++ A A Q A A+ QE + R+ Q+ +LD + E QLQ ++ +
Sbjct: 665 EQARAELTAQHQRRLAAIAQEKDQEMERLREL-----QRASILDMRRDHEEQLQRLKLLK 719
Query: 244 DR 245
DR
Sbjct: 720 DR 721
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,646,101
Number of Sequences: 37866
Number of extensions: 698048
Number of successful extensions: 5406
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 83
Number of HSP's successfully gapped in prelim test: 282
Number of HSP's that attempted gapping in prelim test: 4510
Number of HSP's gapped (non-prelim): 1129
length of query: 431
length of database: 18,247,518
effective HSP length: 105
effective length of query: 326
effective length of database: 14,271,588
effective search space: 4652537688
effective search space used: 4652537688
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.