Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 88014609
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|88014609 coiled-coil domain containing 125 [Homo sapiens]
(511 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|88014609 coiled-coil domain containing 125 [Homo sapiens] 1022 0.0
gi|55770834 centromere protein F [Homo sapiens] 51 2e-06
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 50 5e-06
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 50 6e-06
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 48 2e-05
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 48 2e-05
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 48 2e-05
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 47 5e-05
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 47 5e-05
gi|210032790 hypothetical protein LOC27146 [Homo sapiens] 45 1e-04
gi|4885583 Rho-associated, coiled-coil containing protein kinase... 45 2e-04
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 45 2e-04
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 45 2e-04
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 45 2e-04
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 45 2e-04
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 45 2e-04
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 45 2e-04
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 45 2e-04
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 45 2e-04
gi|4502443 dystonin isoform 1e precursor [Homo sapiens] 45 2e-04
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 44 3e-04
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 44 3e-04
gi|115495445 ankyrin repeat domain 30A [Homo sapiens] 44 3e-04
gi|118498362 kinectin 1 isoform b [Homo sapiens] 44 5e-04
gi|118498356 kinectin 1 isoform a [Homo sapiens] 44 5e-04
gi|118498368 kinectin 1 isoform c [Homo sapiens] 44 5e-04
gi|33620775 kinectin 1 isoform a [Homo sapiens] 44 5e-04
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 44 5e-04
gi|16262452 cingulin [Homo sapiens] 43 6e-04
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 43 8e-04
>gi|88014609 coiled-coil domain containing 125 [Homo sapiens]
Length = 511
Score = 1022 bits (2642), Expect = 0.0
Identities = 511/511 (100%), Positives = 511/511 (100%)
Query: 1 MSKVARSSSESDVQLWETEEDDMTEGDLGYGLGRKPGGIYEIEFSHRSRKRSDGKNFSPP 60
MSKVARSSSESDVQLWETEEDDMTEGDLGYGLGRKPGGIYEIEFSHRSRKRSDGKNFSPP
Sbjct: 1 MSKVARSSSESDVQLWETEEDDMTEGDLGYGLGRKPGGIYEIEFSHRSRKRSDGKNFSPP 60
Query: 61 PFPRKGEERNEASFQYSKHKSQQDTFPQVSRISNYRRQSSTVDSNSELSNEELRQCLNET 120
PFPRKGEERNEASFQYSKHKSQQDTFPQVSRISNYRRQSSTVDSNSELSNEELRQCLNET
Sbjct: 61 PFPRKGEERNEASFQYSKHKSQQDTFPQVSRISNYRRQSSTVDSNSELSNEELRQCLNET 120
Query: 121 LEEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQAVLQKTMEQNRSLEKEIN 180
LEEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQAVLQKTMEQNRSLEKEIN
Sbjct: 121 LEEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQAVLQKTMEQNRSLEKEIN 180
Query: 181 ALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLKENLKVKTEEIKMLKSDNAVLNQRYL 240
ALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLKENLKVKTEEIKMLKSDNAVLNQRYL
Sbjct: 181 ALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLKENLKVKTEEIKMLKSDNAVLNQRYL 240
Query: 241 EALAMLDIKQQKMAQENMCCDKSGFAEASGLELAVLGACLCHGPGGNPCSCARMAASTRK 300
EALAMLDIKQQKMAQENMCCDKSGFAEASGLELAVLGACLCHGPGGNPCSCARMAASTRK
Sbjct: 241 EALAMLDIKQQKMAQENMCCDKSGFAEASGLELAVLGACLCHGPGGNPCSCARMAASTRK 300
Query: 301 LLLQLKQELEILQKSKEEAYVMADAFRIAFEQQLMRKNDQALQLTQMDKMHKKATKWMNW 360
LLLQLKQELEILQKSKEEAYVMADAFRIAFEQQLMRKNDQALQLTQMDKMHKKATKWMNW
Sbjct: 301 LLLQLKQELEILQKSKEEAYVMADAFRIAFEQQLMRKNDQALQLTQMDKMHKKATKWMNW 360
Query: 361 KHLKEDGFPSPRSKKTFGQRLLGMLPSENSSKRMEDQDSPQEVLKMLIDLLNDKEEALAH 420
KHLKEDGFPSPRSKKTFGQRLLGMLPSENSSKRMEDQDSPQEVLKMLIDLLNDKEEALAH
Sbjct: 361 KHLKEDGFPSPRSKKTFGQRLLGMLPSENSSKRMEDQDSPQEVLKMLIDLLNDKEEALAH 420
Query: 421 QRKVSYMLARALEDKDTASNENKEKNPIKENFPFNNPWRKTSEFSVLGDPIHSSVCILNS 480
QRKVSYMLARALEDKDTASNENKEKNPIKENFPFNNPWRKTSEFSVLGDPIHSSVCILNS
Sbjct: 421 QRKVSYMLARALEDKDTASNENKEKNPIKENFPFNNPWRKTSEFSVLGDPIHSSVCILNS 480
Query: 481 VGCICSIQHSQIDPNYRTLKRSHSLPSSIIF 511
VGCICSIQHSQIDPNYRTLKRSHSLPSSIIF
Sbjct: 481 VGCICSIQHSQIDPNYRTLKRSHSLPSSIIF 511
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 51.2 bits (121), Expect = 2e-06
Identities = 87/418 (20%), Positives = 171/418 (40%), Gaps = 56/418 (13%)
Query: 69 RNEASFQYSKHK------SQQDTFPQVSRISNYRRQSSTVDSNSELSNEELRQCLNETLE 122
R E +FQ S+ K S ++ + + + ++ Q + + E + ++QCLN++
Sbjct: 462 RAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQN 521
Query: 123 EVEMLKTELEASQRQLRGKEEAL----------KILQSMAILGKATSHTQAVLQKTMEQN 172
E +K + + + LR +E + K+ ++A L K +Q +L+K
Sbjct: 522 FAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHI 581
Query: 173 RSL-------EKEINALQWEIEFDHNRFKNIEES------WIQKYDRLNCENAVLKENLK 219
L EKE AL +E ++ ++E W + ++L + KENL+
Sbjct: 582 EQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQ 641
Query: 220 VKTEEIKMLKSDNAVLNQRYLEALAMLDIKQQKMAQE-----NMCCDKSGFAEASGLELA 274
K ++ + + Y E + L++ ++ ++ E N+ KS E L
Sbjct: 642 SKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLAYM 701
Query: 275 VLGACLCHGPGGNPCSCARMAASTRKLLLQ---LKQELEILQK---SKEEAYVMADAFRI 328
L + M T +L Q L+ +L++L K+ Y A
Sbjct: 702 ELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLLSNEIMDKDRCYQDLHA-EY 760
Query: 329 AFEQQLMRKNDQALQLTQMDKMHKKATKWMNWKHLKEDGFPSPRSKKTFGQRLLGMLPSE 388
+ L++ D +L +T D H+++ + + F + G++ G +PSE
Sbjct: 761 ESLRDLLKSKDASL-VTNED--HQRSLLAFDQQPAMHHSFAN-----IIGEQ--GSMPSE 810
Query: 389 NSSKRMEDQDSPQE--VLKMLIDLLNDKEEALAHQRKVSYMLARALEDKDTASNENKE 444
S R+E SP+ +L+ +D L E +L Q++++ L + E+ E +E
Sbjct: 811 RSECRLEADQSPKNSAILQNRVDSL---EFSLESQKQMNSDLQKQCEELVQIKGEIEE 865
Score = 39.7 bits (91), Expect = 0.007
Identities = 96/440 (21%), Positives = 185/440 (42%), Gaps = 72/440 (16%)
Query: 65 KGEERNEASFQYSKHKSQQDTFPQVSRISNYRRQSSTVDSNSELSNEELRQCLNETLEEV 124
+G E + + + K + + RIS +S+ ++ + +E Q ++ +
Sbjct: 2381 RGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAM 2440
Query: 125 EMLKTEL-EASQR--QLRGKEEALKIL-QSMAILGKATSHTQAVLQKTMEQNRS----LE 176
EML+T+L E ++R L +EA K Q+++ + +A L + +++ ++ L+
Sbjct: 2441 EMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQ 2500
Query: 177 KEINALQWEIE----------FDHNRFKN---IEESWIQKYDRLNCENAVLKE------N 217
+N L E+E + +R KN +E + K ++ E+ + KE N
Sbjct: 2501 SSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRN 2560
Query: 218 LKVKTEE-IKMLKSDNAVLNQRYLEALAMLDIKQQKMAQENMCCDKSGFAEASGLELAVL 276
L V+ E+ I++L+S NA L Q LE L K + E DK F E
Sbjct: 2561 LTVELEQKIQVLQSKNASL-QDTLEVL-QSSYKNLENELELTKMDKMSFVE--------- 2609
Query: 277 GACLCHGPGGNPCSCARMAASTRKLLLQLKQELEILQKSKE-EAYVMADAFRIAFEQQLM 335
+M A +L ++ E+ QK+ E + + + R+A E QL+
Sbjct: 2610 -------------KVNKMTAKETELQREMH---EMAQKTAELQEELSGEKNRLAGELQLL 2653
Query: 336 -----RKNDQALQLTQMDKMHKKATKWMNWKHLKEDGFPSPRSKKTFGQRLLGMLPSENS 390
DQ +LT + KK+ M+ ++++G + ++ + L + +E
Sbjct: 2654 LEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEG----KVREEIAEYQLRLHEAEKK 2709
Query: 391 SKR-MEDQDSPQEV-LKMLIDLLNDKEEALAHQRKVSYMLARALED-----KDTASNENK 443
+ + D + EV ++ + L KEE L+ Q+ +L + E+ K T +
Sbjct: 2710 HQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEE 2769
Query: 444 EKNPIKENFPFNNPWRKTSE 463
K +N + N +K +E
Sbjct: 2770 LKKTKMDNLKYVNQLKKENE 2789
Score = 35.4 bits (80), Expect = 0.12
Identities = 52/199 (26%), Positives = 79/199 (39%), Gaps = 45/199 (22%)
Query: 68 ERNEASFQYSKHKSQQDTFPQVSRISNYRRQSSTVDSNSELSNEELRQCLNETLEEVEML 127
ERN+ +F K Q D +V IS + V + L N+EL+ L E+ +E E L
Sbjct: 1184 ERNQCNF-----KPQMDL--EVKEISLDSYNAQLVQLEAMLRNKELK--LQESEKEKECL 1234
Query: 128 KTELEASQRQLRGKEEALKILQSMAILG-----------------------KATSHTQAV 164
+ EL+ + L L+ +QS I G +H Q
Sbjct: 1235 QHELQTIRGDLETSN--LQDMQSQEISGLKDCEIDAEEKYISGPHELSTSQNDNAHLQCS 1292
Query: 165 LQKTMEQNRSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLK--ENLKVKT 222
LQ TM + LEK LQ E +++ + E R C A K E +
Sbjct: 1293 LQTTMNKLNELEKICEILQAE------KYELVTE---LNDSRSECITATRKMAEEVGKLL 1343
Query: 223 EEIKMLKSDNAVLNQRYLE 241
E+K+L D+ +L+ +E
Sbjct: 1344 NEVKILNDDSGLLHGELVE 1362
Score = 35.4 bits (80), Expect = 0.12
Identities = 39/173 (22%), Positives = 78/173 (45%), Gaps = 16/173 (9%)
Query: 64 RKGEERNE-ASFQYSKHKSQQDTFPQVSRISNYRRQSSTVDSNSE-LSNEELRQCLNETL 121
++G+ R E A +Q H++++ Q + ++ + + E L+++E +CL+
Sbjct: 2688 KEGKVREEIAEYQLRLHEAEKKH--QALLLDTNKQYEVEIQTYREKLTSKE--ECLSSQK 2743
Query: 122 EEVEMLKTELEASQRQLRGKEEALKILQSMAI--------LGKATSHTQAVLQKTMEQNR 173
E+++LK+ E L+ + L+ L+ + L K Q ++ ++ +
Sbjct: 2744 LEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCK 2803
Query: 174 SLEKEINALQWEIEFDHNRFKNIEESWIQ--KYDRLNCENAVLKENLKVKTEE 224
LE+E LQ E+ + + + K D L E LKE L+ KT+E
Sbjct: 2804 QLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTKE 2856
Score = 34.7 bits (78), Expect = 0.21
Identities = 61/291 (20%), Positives = 110/291 (37%), Gaps = 53/291 (18%)
Query: 91 RISNYRRQSSTVDSNSELSNEELRQCLNETLEEVEMLKTELEASQRQLRGKE-------- 142
R+ N R+ +N E + E E VE LK ++E + LRG E
Sbjct: 2337 RVENLERELEIARTNQEHAALEAENSKGE----VETLKAKIEGMTQSLRGLELDVVTIRS 2392
Query: 143 -------EALKILQSMAILGKATSHTQAVLQK--------------TMEQNRSLEKEINA 181
E K + ++ L S + +LQ+ ME ++ KE+N
Sbjct: 2393 EKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNE 2452
Query: 182 LQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLKENLKVKTEEIKMLKSDNAVLNQRYLE 241
+ D K E++ + + L E A L + L +L+S L Q +
Sbjct: 2453 RVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVED 2512
Query: 242 ALAMLDIKQQKMAQ-ENMCCDKSGF-AEASGLELAVLGACLCHGPGGNPCSCARMAASTR 299
L+ K +++++ +N D+ ++ S +E G R
Sbjct: 2513 GKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVE-------------GEHQLWKEQNLELR 2559
Query: 300 KLLLQLKQELEILQKSKEEAYVMADAFRIAFEQQLMRKNDQALQLTQMDKM 350
L ++L+Q++++LQ + D + Q + + L+LT+MDKM
Sbjct: 2560 NLTVELEQKIQVLQSKNAS---LQDTLEVL--QSSYKNLENELELTKMDKM 2605
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding domain
1 [Homo sapiens]
Length = 1412
Score = 50.1 bits (118), Expect = 5e-06
Identities = 78/363 (21%), Positives = 163/363 (44%), Gaps = 54/363 (14%)
Query: 122 EEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQAVLQKTMEQNRSLEKEINA 181
+E +K LE Q +++ EE ++ + +L + +H + + +LE E
Sbjct: 732 QEKNRVKEALEEEQTRVQELEE--RLARQKEVLESSIAHEKR------KAKEALESEKRK 783
Query: 182 LQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLKENLKVKT---------EEIKMLKSDN 232
+Q ++E + K I ES I Y++ + A+ KE KV+ EE+++ +
Sbjct: 784 VQ-DLENHLTQQKEISESNIA-YEKRKAKEAMEKEKKKVQDLENRLTKQKEELELKEQKE 841
Query: 233 AVLNQRYLEALAMLDIKQQKMAQENMCCDKSGFAEASGLELAVLGACLCHGPGGNPCSCA 292
VLN + +ALAM++ Q+ A E++ AE+ L+L A L
Sbjct: 842 DVLNNKLSDALAMVEETQKTKATESL------KAESLALKLNETLAEL------------ 883
Query: 293 RMAASTRKLLLQLKQELEILQKSKEEAYVMADAFRIAFEQQLMRKNDQALQLTQMDKMHK 352
+T+ ++ +++ L + QK + ++ R FE+++M +Q Q Q +
Sbjct: 884 ---ETTKTKMIMVEERLILQQKMVKALQDEQESQRHGFEEEIMEYKEQIKQHAQTIVSLE 940
Query: 353 KATKWMNWKHLK--------EDGFPSPRSKKTFGQRLLGMLPSENSSKRMEDQDSPQEVL 404
+ + + H K +D P+P+ ++ + M +E+S+K M + ++L
Sbjct: 941 EKLQKVTQHHKKIEGEIATLKDNDPAPKEERPQDPLVAPM--TESSAKDMAYEHLIDDLL 998
Query: 405 KMLIDLLNDKEEALAHQRKVSYMLARALEDKDTASNENKEKNPIKENFPFNNPWRKTSEF 464
++L+ +E + ++ ++ +R + D NE K+K +++N +++ E
Sbjct: 999 AAQKEILSQQEVIMKLRKDLTEAHSR-MSDLRGELNE-KQKMELEQNVVLVQ--QQSKEL 1054
Query: 465 SVL 467
SVL
Sbjct: 1055 SVL 1057
Score = 35.0 bits (79), Expect = 0.16
Identities = 59/284 (20%), Positives = 112/284 (39%), Gaps = 46/284 (16%)
Query: 98 QSSTVDSNSELSNEELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKILQS------- 150
++ + L E L LNETL E+E KT++ + +L +++ +K LQ
Sbjct: 857 ETQKTKATESLKAESLALKLNETLAELETTKTKMIMVEERLILQQKMVKALQDEQESQRH 916
Query: 151 ------MAILGKATSHTQAV------LQKTMEQNRSLEKEINALQ------WEIEFDHNR 192
M + H Q + LQK + ++ +E EI L+ E
Sbjct: 917 GFEEEIMEYKEQIKQHAQTIVSLEEKLQKVTQHHKKIEGEIATLKDNDPAPKEERPQDPL 976
Query: 193 FKNIEESWIQ--KYDRLNCENAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAMLDIKQ 250
+ ES + Y+ L + ++ + + E I L+ D + R + L+ KQ
Sbjct: 977 VAPMTESSAKDMAYEHLIDDLLAAQKEILSQQEVIMKLRKDLTEAHSRMSDLRGELNEKQ 1036
Query: 251 QKMAQENMCCDKSGFAEASGLELAVLGACLCHGPGGNPCSCARMAASTRKLLLQLKQELE 310
+ ++N+ + EL+VL A+M++ K +LK E
Sbjct: 1037 KMELEQNVV-----LVQQQSKELSVLKE-----------KMAQMSSLVEKKDRELKALEE 1080
Query: 311 ILQKSKEEAYVMADAFRIAFEQQLMRKNDQALQLTQMDKMHKKA 354
L+ S+E+ + + + EQ+ +K Q++ +H +A
Sbjct: 1081 ALRASQEKHRLQLNTEK---EQKPRKKTQTCDTSVQIEPVHTEA 1121
Score = 34.3 bits (77), Expect = 0.28
Identities = 38/191 (19%), Positives = 87/191 (45%), Gaps = 27/191 (14%)
Query: 88 QVSRISNYRRQSSTVD---SNSELSNEELRQCLNETL----------EEVEMLKTELEAS 134
+VSR+S+Y +S D +N + EL Q ++ET ++ ++L +++A
Sbjct: 236 EVSRLSDYEIESKYKDVIIANLQNEVAELSQKVSETTTSRQNEKEISQKCQVLDEDIDAK 295
Query: 135 QRQLRGKEEALKILQSMAILGKATSHTQAVLQKTMEQN---RSLEKEINALQWEIEFDHN 191
Q++++ + + LQ +++ + Q E+N SL+ E L+ +
Sbjct: 296 QKEIQSLKSQISALQK--------GYSKVLCQTLSERNSEITSLKNEGENLKRDNAITSG 347
Query: 192 RFKNIEESWIQK---YDRLNCENAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAMLDI 248
++++ + K +L E + LK K K +++ L S +VL + + A ++
Sbjct: 348 MVSSLQKDILAKDEQVQQLKEEVSHLKSQNKDKDHQLEALGSRCSVLKEELKQEDAHREL 407
Query: 249 KQQKMAQENMC 259
++ + + +C
Sbjct: 408 REAQEKELKLC 418
Score = 32.7 bits (73), Expect = 0.81
Identities = 72/372 (19%), Positives = 148/372 (39%), Gaps = 43/372 (11%)
Query: 80 KSQQDTFPQVSRISNYR-----RQSSTVDSNSELSNEELRQCLNETLEEVEMLKTELEAS 134
K ++D SR+S+ R +Q ++ N L ++ ++ L+ E++ + + +E
Sbjct: 1013 KLRKDLTEAHSRMSDLRGELNEKQKMELEQNVVLVQQQSKE-LSVLKEKMAQMSSLVEKK 1071
Query: 135 QRQLRGKEEALKILQSMAILGKATSHTQAVLQKTMEQNRSLEKE-INALQWEIEFDHNRF 193
R+L+ EEAL+ Q L T Q +KT + S++ E ++ + + F
Sbjct: 1072 DRELKALEEALRASQEKHRLQLNTEKEQKPRKKTQTCDTSVQIEPVHTEAFSSSQEQQSF 1131
Query: 194 KNI--------EESWIQKYDRLNCENAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAM 245
++ E IQ+ + E L+ + +E++ +S + +Q +
Sbjct: 1132 SDLGVRCKGSRHEEVIQRQKKALSE-------LRARIKELEKARSPDHKDHQNE----SF 1180
Query: 246 LDIKQQKM---AQENMCCDKSGFAEASGLELAVLGACLCHGPGGN------PCSCARMAA 296
LD+K +M Q+ + K S +E+ LC+ G+ A
Sbjct: 1181 LDLKNLRMENNVQKILLDAKPDLPTLSRIEILAPQNGLCNARFGSAMEKSGKMDVAEALE 1240
Query: 297 STRKLLLQLKQELEILQKSKEEAYVMADAFRIAFEQQLMRKNDQALQLTQMDKMHKKATK 356
+ KL L + + L L K M+ + + + R+ L+ +D + K T+
Sbjct: 1241 LSEKLYLDMSKTLGSLMNIKN----MSGHVSMKYLSRQEREKVNQLRQRDLDLVFDKITQ 1296
Query: 357 WMNWKHLKED---GFPSPRSKKTFGQRLLGMLPSENSSKRMEDQDSPQEVLKMLIDLLND 413
N KE+ G+ + + + M S+ +K +D E +L + L
Sbjct: 1297 LKNQLGRKEELLRGYEKDVEQLRRSKVSIEMYQSQ-VAKLEDDIYKEAEEKALLKEALER 1355
Query: 414 KEEALAHQRKVS 425
E L +++++
Sbjct: 1356 MEHQLCQEKRIN 1367
Score = 29.3 bits (64), Expect = 8.9
Identities = 34/192 (17%), Positives = 76/192 (39%), Gaps = 9/192 (4%)
Query: 71 EASFQYSKHKSQQDTFPQVSRISNYR----RQSSTVDSNSELSNEELRQCLNETLEEVEM 126
E+S + K K+++ + ++ + +Q +SN + ++ + + ++V+
Sbjct: 763 ESSIAHEKRKAKEALESEKRKVQDLENHLTQQKEISESNIAYEKRKAKEAMEKEKKKVQD 822
Query: 127 LKTELEASQRQLRGKEEALKILQSMAILGKA-TSHTQAVLQKTMEQNRSLEKEINALQWE 185
L+ L + +L KE+ +L + A TQ + SL ++N E
Sbjct: 823 LENRLTKQKEELELKEQKEDVLNNKLSDALAMVEETQKTKATESLKAESLALKLNETLAE 882
Query: 186 IEFDHNRFKNIEESWIQKYDRLNCENAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAM 245
+E + +EE I + + + EEI K +++ + +
Sbjct: 883 LETTKTKMIMVEERLILQQKMVKALQDEQESQRHGFEEEIMEYKEQ----IKQHAQTIVS 938
Query: 246 LDIKQQKMAQEN 257
L+ K QK+ Q +
Sbjct: 939 LEEKLQKVTQHH 950
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 49.7 bits (117), Expect = 6e-06
Identities = 86/388 (22%), Positives = 157/388 (40%), Gaps = 84/388 (21%)
Query: 117 LNETLEEVEMLKTELEASQRQLRGKEEALK----ILQSMAILGKATS------------- 159
L +TLEE+E+ +E ++ L ++E++K +LQS + KAT
Sbjct: 284 LRKTLEEMEL---RIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAE 340
Query: 160 ----HTQAVLQKTMEQNRSLEKEINALQWEIEFDHNRFKNIEESWIQK-----YDRLNCE 210
H +++L++ ++N L +E+ H RF+N +S K + + +
Sbjct: 341 MHVHHLESLLEQKEKENSMLREEM----------HRRFENAPDSAKTKALQTVIEMKDSK 390
Query: 211 NAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAMLDI-----KQQKMAQENMCCDKSGF 265
+ ++ L+ EEI+MLKS+ A+ + E + +++ K K E + + S
Sbjct: 391 ISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSS- 449
Query: 266 AEASGLELAVLGACLCHGPGGNPCSCARMAASTRKLLLQL----------KQELEILQKS 315
EA EL A L G +R L +L KQ +E+L++S
Sbjct: 450 KEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKES 509
Query: 316 ---KEEAYVM----ADAFRIAFEQQLMRKNDQALQLTQMDKMHKKATKWMNWKHLKEDGF 368
KE+ + DA R+ E++ N + Q+ D +K T+ LK+
Sbjct: 510 LTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQI--QDMAEEKGTQAGEIHDLKDMLD 567
Query: 369 PSPRSKKTFGQRLLGMLPSENSSKRMEDQDSPQEVLKMLI-----------DLLNDKEEA 417
R +++ EN +++ D++ LK + L EEA
Sbjct: 568 VKERKVNVLQKKI------ENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEA 621
Query: 418 LAHQRKVSYMLARALEDKDTASNENKEK 445
LA + + + R E +D E +E+
Sbjct: 622 LAEKERT---IERLKEQRDRDEREKQEE 646
Score = 40.8 bits (94), Expect = 0.003
Identities = 70/341 (20%), Positives = 138/341 (40%), Gaps = 36/341 (10%)
Query: 112 ELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKIL-QSMAILGKATSHTQAVLQKTME 170
+L+ L+ +V +L+ ++E Q QLR KE+ + L + + L T++T L E
Sbjct: 561 DLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEE 620
Query: 171 QNRSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLKENLKVKTEEIKMLKS 230
E+ I L+ + + D + +++ + L + ++L+ +L K + LK
Sbjct: 621 ALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKE 680
Query: 231 DNAVLNQRYLEALAMLDIKQQKMAQENMCCDKSGFAEASGLELAVLGACLCHGPGGNPCS 290
+ L L+ + L + + Q+ C K E A+
Sbjct: 681 HASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALE-------------- 726
Query: 291 CARMAASTRKLLLQLKQELEILQKSKEEAYVMADAFRIAFEQQLMRKNDQALQLTQMDKM 350
AR + + L++E+ + +A D ++ KND+ ++ ++++
Sbjct: 727 -ARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQ 785
Query: 351 HKKATKWM-NWKHLKEDGFPSPRSKKTFGQRLLGMLPSENSSKRMED--QDSPQEV---L 404
K K + N KH ++ KK Q L ++R ED DS Q++ L
Sbjct: 786 VKDQNKKVANLKHKEQ------VEKKKSAQML-------EEARRREDNLNDSSQQLQDSL 832
Query: 405 KMLIDLLNDKEEALAHQRKVSYMLARALEDKDTASNENKEK 445
+ D + + EEAL +++ L +++A N EK
Sbjct: 833 RKKDDRIEELEEALRESVQITAEREMVLAQEESA-RTNAEK 872
Score = 40.0 bits (92), Expect = 0.005
Identities = 47/188 (25%), Positives = 83/188 (44%), Gaps = 18/188 (9%)
Query: 48 SRKRSDGKNFSPPPFP---RKGEERNEASFQYSKHKSQQDTFPQVSRISNYRRQSSTVDS 104
+R+R D N S RK ++R E + + +S Q T + ++ Q + +
Sbjct: 814 ARRREDNLNDSSQQLQDSLRKKDDRIE-ELEEALRESVQITAEREMVLA----QEESART 868
Query: 105 NSELSNEELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQAV 164
N+E EEL + + +E+E +K +L ++Q+ L KE L L++ + H + V
Sbjct: 869 NAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRA-----ERRKHLEEV 923
Query: 165 LQKTMEQNRSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLKENLKVKTEE 224
L+ E + E +A +E ++ K EE L E L + LK +T+
Sbjct: 924 LEMKQEALLAAISEKDANIALLELSSSKKKTQEE-----VAALKREKDRLVQQLKQQTQN 978
Query: 225 IKMLKSDN 232
L +DN
Sbjct: 979 RMKLMADN 986
Score = 31.6 bits (70), Expect = 1.8
Identities = 39/181 (21%), Positives = 71/181 (39%), Gaps = 26/181 (14%)
Query: 78 KHKSQQDTFPQVSRISNYRRQSSTVDSNSELSNEELRQCLN--ETLEEVEMLKTELEASQ 135
KHK Q + + RR+ ++ +S+ + LR+ + E LEE ++ A +
Sbjct: 797 KHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAER 856
Query: 136 RQLRGKEEALK---------ILQSMAILGKATSHTQAVLQKTMEQNRSLEKEINALQWEI 186
+ +EE+ + +L +M + + +A L T + E + L+ E
Sbjct: 857 EMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAE- 915
Query: 187 EFDHNRFKNIEESWIQKYDRL---------NCENAVLKENLKVKTEEIKMLKSDNAVLNQ 237
R K++EE K + L N L + K EE+ LK + L Q
Sbjct: 916 -----RRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQ 970
Query: 238 R 238
+
Sbjct: 971 Q 971
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 48.1 bits (113), Expect = 2e-05
Identities = 73/367 (19%), Positives = 145/367 (39%), Gaps = 70/367 (19%)
Query: 117 LNETLEEVEMLKTELEASQRQLRGKEEALK----ILQSMAILGKATS------------- 159
L +TLEE+E+ +E ++ L ++E++K +LQS + KAT
Sbjct: 284 LRKTLEEMEL---RIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAE 340
Query: 160 ----HTQAVLQKTMEQNRSLEKEINALQWEIEFDHNRFKNIEESWIQK-----YDRLNCE 210
H +++L++ ++N L +E+ H RF+N +S K + + +
Sbjct: 341 MHVHHLESLLEQKEKENSMLREEM----------HRRFENAPDSAKTKALQTVIEMKDSK 390
Query: 211 NAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAMLDI-KQQKMAQENMCCDKSGFAEAS 269
+ ++ L+ EEI+MLKS+ A+ + E + +++ + +N
Sbjct: 391 ISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRK 450
Query: 270 GLELAVLGACLCHGPGGNPCSCARMAASTRKLLLQLKQELEILQKSKEEAYVMADAFRIA 329
EL L L + + +++ + LK+ L ++ DA R+
Sbjct: 451 DTELLALQTKL--------ETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLR 502
Query: 330 FEQQLMRKNDQALQLTQMDKMHKKATKWMNWKHLKEDGFPSPRSKKTFGQRLLGMLPSEN 389
E++ N + Q+ D +K T+ LK+ R +++ EN
Sbjct: 503 LEEKETMLNKKTKQI--QDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKI------EN 554
Query: 390 SSKRMEDQDSPQEVLKMLI-----------DLLNDKEEALAHQRKVSYMLARALEDKDTA 438
+++ D++ LK + L EEALA + + + R E +D
Sbjct: 555 LQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERT---IERLKEQRDRD 611
Query: 439 SNENKEK 445
E +E+
Sbjct: 612 EREKQEE 618
Score = 40.8 bits (94), Expect = 0.003
Identities = 70/341 (20%), Positives = 138/341 (40%), Gaps = 36/341 (10%)
Query: 112 ELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKIL-QSMAILGKATSHTQAVLQKTME 170
+L+ L+ +V +L+ ++E Q QLR KE+ + L + + L T++T L E
Sbjct: 533 DLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEE 592
Query: 171 QNRSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLKENLKVKTEEIKMLKS 230
E+ I L+ + + D + +++ + L + ++L+ +L K + LK
Sbjct: 593 ALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKE 652
Query: 231 DNAVLNQRYLEALAMLDIKQQKMAQENMCCDKSGFAEASGLELAVLGACLCHGPGGNPCS 290
+ L L+ + L + + Q+ C K E A+
Sbjct: 653 HASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALE-------------- 698
Query: 291 CARMAASTRKLLLQLKQELEILQKSKEEAYVMADAFRIAFEQQLMRKNDQALQLTQMDKM 350
AR + + L++E+ + +A D ++ KND+ ++ ++++
Sbjct: 699 -ARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQ 757
Query: 351 HKKATKWM-NWKHLKEDGFPSPRSKKTFGQRLLGMLPSENSSKRMED--QDSPQEV---L 404
K K + N KH ++ KK Q L ++R ED DS Q++ L
Sbjct: 758 VKDQNKKVANLKHKEQ------VEKKKSAQML-------EEARRREDNLNDSSQQLQDSL 804
Query: 405 KMLIDLLNDKEEALAHQRKVSYMLARALEDKDTASNENKEK 445
+ D + + EEAL +++ L +++A N EK
Sbjct: 805 RKKDDRIEELEEALRESVQITAEREMVLAQEESA-RTNAEK 844
Score = 40.0 bits (92), Expect = 0.005
Identities = 47/188 (25%), Positives = 83/188 (44%), Gaps = 18/188 (9%)
Query: 48 SRKRSDGKNFSPPPFP---RKGEERNEASFQYSKHKSQQDTFPQVSRISNYRRQSSTVDS 104
+R+R D N S RK ++R E + + +S Q T + ++ Q + +
Sbjct: 786 ARRREDNLNDSSQQLQDSLRKKDDRIE-ELEEALRESVQITAEREMVLA----QEESART 840
Query: 105 NSELSNEELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQAV 164
N+E EEL + + +E+E +K +L ++Q+ L KE L L++ + H + V
Sbjct: 841 NAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRA-----ERRKHLEEV 895
Query: 165 LQKTMEQNRSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLKENLKVKTEE 224
L+ E + E +A +E ++ K EE L E L + LK +T+
Sbjct: 896 LEMKQEALLAAISEKDANIALLELSSSKKKTQEE-----VAALKREKDRLVQQLKQQTQN 950
Query: 225 IKMLKSDN 232
L +DN
Sbjct: 951 RMKLMADN 958
Score = 31.6 bits (70), Expect = 1.8
Identities = 39/181 (21%), Positives = 71/181 (39%), Gaps = 26/181 (14%)
Query: 78 KHKSQQDTFPQVSRISNYRRQSSTVDSNSELSNEELRQCLN--ETLEEVEMLKTELEASQ 135
KHK Q + + RR+ ++ +S+ + LR+ + E LEE ++ A +
Sbjct: 769 KHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAER 828
Query: 136 RQLRGKEEALK---------ILQSMAILGKATSHTQAVLQKTMEQNRSLEKEINALQWEI 186
+ +EE+ + +L +M + + +A L T + E + L+ E
Sbjct: 829 EMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAE- 887
Query: 187 EFDHNRFKNIEESWIQKYDRL---------NCENAVLKENLKVKTEEIKMLKSDNAVLNQ 237
R K++EE K + L N L + K EE+ LK + L Q
Sbjct: 888 -----RRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQ 942
Query: 238 R 238
+
Sbjct: 943 Q 943
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 47.8 bits (112), Expect = 2e-05
Identities = 42/182 (23%), Positives = 91/182 (50%), Gaps = 10/182 (5%)
Query: 67 EERNEASFQYSKHKSQQDTFPQVS-RISNYRRQSSTVDS-NSELS-NEELRQCLNETLEE 123
+E +E + K K D+F ++ ++ + +++S +D N EL N E +C + + +
Sbjct: 663 QENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQ 722
Query: 124 VEMLKTELEASQRQLRGKEEALKI----LQSMAILGKATSHTQAVLQKTMEQNRSLEKEI 179
+++ ELE+ + QL+ E LK + + + + LQKT+E + +++
Sbjct: 723 LQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQL 782
Query: 180 NALQWEIEFDHNRF-KNIEESWI--QKYDRLNCENAVLKENLKVKTEEIKMLKSDNAVLN 236
+ ++E ++ KN+EE I ++ ++L EN L++ ++ K L+ +N L
Sbjct: 783 ESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLR 842
Query: 237 QR 238
Q+
Sbjct: 843 QQ 844
Score = 35.8 bits (81), Expect = 0.095
Identities = 84/414 (20%), Positives = 171/414 (41%), Gaps = 44/414 (10%)
Query: 67 EERNEASFQYSKHKSQQDTFPQVSRISNYRRQSSTVD-SNSELSNEELRQCLNETLEEVE 125
EER+ F S Q RQ +V+ ++++ LRQ L E E++
Sbjct: 216 EERDGLHFLPHASSSAQSPCGSPGMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLL 275
Query: 126 MLKTELEASQRQL-RGKEEALKILQSMAILGKATSHTQAVLQKTMEQNRSLEKEINALQ- 183
K ELE + +L R ++E + +L A+ +K + ++ LE E++ +
Sbjct: 276 DCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDK-LESEVSRYKE 334
Query: 184 --WEIEFDHNRFKNI-EESWIQKYDRLNCENAVLKENLKVKTEEIKMLKSDNAVLNQRYL 240
+IEF R + + E++ + + E+ + E + +++++ L+ +N L +
Sbjct: 335 RLHDIEFYKARVEELKEDNQVLLETKTMLEDQL--EGTRARSDKLHELEKENLQLKAKLH 392
Query: 241 EALAMLDIKQQK---MAQENMCCD---KSGFAEA--SGLELAVLGACLCHGPGGNPCSCA 292
+ D+ ++K + +ENM + K E+ G EL +
Sbjct: 393 DMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGH 452
Query: 293 RMAASTRKLLLQLKQELEILQKSKEEAYVMADA--------FRIAFEQQLMRKNDQALQL 344
+ T LL+L+ E + L K+ EE D+ ++ E Q + K + L+
Sbjct: 453 EVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILE- 511
Query: 345 TQMDKMHKKATKWMNWKHLKEDGFPSPRSKKTFGQRLLGMLPSENSSKRMEDQDSPQEVL 404
+++ ++ N ++L +D + + L ENS ++++ + E L
Sbjct: 512 ---NEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETL-----RENSERQIKILEQENEHL 563
Query: 405 KMLIDLLNDKEEALAHQR-----KVSYMLARALEDKDTASNENK---EKNPIKE 450
+ L + + A R K + +L ++ K+T+S +K EK IK+
Sbjct: 564 NQTVSSLRQRSQISAEARVKDIEKENKILHESI--KETSSKLSKIEFEKRQIKK 615
Score = 31.2 bits (69), Expect = 2.3
Identities = 30/161 (18%), Positives = 67/161 (41%), Gaps = 11/161 (6%)
Query: 105 NSELSNEELRQCLNETLEEV-------EMLKTELEASQRQLRGKEEALKILQSMAILGKA 157
N E+ + +L N+ L++ +MLK E E + + E + +
Sbjct: 1190 NLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDR 1249
Query: 158 TSHTQAVLQKTMEQNRSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLKEN 217
+HT + L K E ++ K + +L + + R + ++Y +L+ +
Sbjct: 1250 LNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLD----ITSTK 1305
Query: 218 LKVKTEEIKMLKSDNAVLNQRYLEALAMLDIKQQKMAQENM 258
L + E + LK + N+ L+ + L ++ + + ++NM
Sbjct: 1306 LNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNM 1346
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 47.8 bits (112), Expect = 2e-05
Identities = 42/182 (23%), Positives = 91/182 (50%), Gaps = 10/182 (5%)
Query: 67 EERNEASFQYSKHKSQQDTFPQVS-RISNYRRQSSTVDS-NSELS-NEELRQCLNETLEE 123
+E +E + K K D+F ++ ++ + +++S +D N EL N E +C + + +
Sbjct: 663 QENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQ 722
Query: 124 VEMLKTELEASQRQLRGKEEALKI----LQSMAILGKATSHTQAVLQKTMEQNRSLEKEI 179
+++ ELE+ + QL+ E LK + + + + LQKT+E + +++
Sbjct: 723 LQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQL 782
Query: 180 NALQWEIEFDHNRF-KNIEESWI--QKYDRLNCENAVLKENLKVKTEEIKMLKSDNAVLN 236
+ ++E ++ KN+EE I ++ ++L EN L++ ++ K L+ +N L
Sbjct: 783 ESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLR 842
Query: 237 QR 238
Q+
Sbjct: 843 QQ 844
Score = 35.8 bits (81), Expect = 0.095
Identities = 84/414 (20%), Positives = 171/414 (41%), Gaps = 44/414 (10%)
Query: 67 EERNEASFQYSKHKSQQDTFPQVSRISNYRRQSSTVD-SNSELSNEELRQCLNETLEEVE 125
EER+ F S Q RQ +V+ ++++ LRQ L E E++
Sbjct: 216 EERDGLHFLPHASSSAQSPCGSPGMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLL 275
Query: 126 MLKTELEASQRQL-RGKEEALKILQSMAILGKATSHTQAVLQKTMEQNRSLEKEINALQ- 183
K ELE + +L R ++E + +L A+ +K + ++ LE E++ +
Sbjct: 276 DCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDK-LESEVSRYKE 334
Query: 184 --WEIEFDHNRFKNI-EESWIQKYDRLNCENAVLKENLKVKTEEIKMLKSDNAVLNQRYL 240
+IEF R + + E++ + + E+ + E + +++++ L+ +N L +
Sbjct: 335 RLHDIEFYKARVEELKEDNQVLLETKTMLEDQL--EGTRARSDKLHELEKENLQLKAKLH 392
Query: 241 EALAMLDIKQQK---MAQENMCCD---KSGFAEA--SGLELAVLGACLCHGPGGNPCSCA 292
+ D+ ++K + +ENM + K E+ G EL +
Sbjct: 393 DMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGH 452
Query: 293 RMAASTRKLLLQLKQELEILQKSKEEAYVMADA--------FRIAFEQQLMRKNDQALQL 344
+ T LL+L+ E + L K+ EE D+ ++ E Q + K + L+
Sbjct: 453 EVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILE- 511
Query: 345 TQMDKMHKKATKWMNWKHLKEDGFPSPRSKKTFGQRLLGMLPSENSSKRMEDQDSPQEVL 404
+++ ++ N ++L +D + + L ENS ++++ + E L
Sbjct: 512 ---NEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETL-----RENSERQIKILEQENEHL 563
Query: 405 KMLIDLLNDKEEALAHQR-----KVSYMLARALEDKDTASNENK---EKNPIKE 450
+ L + + A R K + +L ++ K+T+S +K EK IK+
Sbjct: 564 NQTVSSLRQRSQISAEARVKDIEKENKILHESI--KETSSKLSKIEFEKRQIKK 615
Score = 31.2 bits (69), Expect = 2.3
Identities = 30/161 (18%), Positives = 67/161 (41%), Gaps = 11/161 (6%)
Query: 105 NSELSNEELRQCLNETLEEV-------EMLKTELEASQRQLRGKEEALKILQSMAILGKA 157
N E+ + +L N+ L++ +MLK E E + + E + +
Sbjct: 1189 NLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDR 1248
Query: 158 TSHTQAVLQKTMEQNRSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLKEN 217
+HT + L K E ++ K + +L + + R + ++Y +L+ +
Sbjct: 1249 LNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLD----ITSTK 1304
Query: 218 LKVKTEEIKMLKSDNAVLNQRYLEALAMLDIKQQKMAQENM 258
L + E + LK + N+ L+ + L ++ + + ++NM
Sbjct: 1305 LNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNM 1345
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 46.6 bits (109), Expect = 5e-05
Identities = 37/168 (22%), Positives = 75/168 (44%), Gaps = 9/168 (5%)
Query: 69 RNEASFQYSKHKSQQDTFPQVSRISNYRRQSSTVDSNSELSNEELRQCLNETLEEVEMLK 128
R + F + + S+ ++ N + + + + + L+ +++ +E ++ K
Sbjct: 626 RTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEK 685
Query: 129 TELEASQRQLRGKEEALKILQSMAILGKATSHTQAV--LQKTME-------QNRSLEKEI 179
L Q QL + LK LQ + K+ T + LQK +E + +LE+E+
Sbjct: 686 DNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEV 745
Query: 180 NALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLKENLKVKTEEIKM 227
LQ + E + K E +K+ +L EN++LK+ K + +K+
Sbjct: 746 QELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKI 793
Score = 43.5 bits (101), Expect = 5e-04
Identities = 35/162 (21%), Positives = 72/162 (44%), Gaps = 4/162 (2%)
Query: 88 QVSRISNYRRQSSTVDSNSELSNEELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKI 147
+V +++N+ ++ + S LS E+L++ + E EE+E L+ + ++ L + +
Sbjct: 2110 EVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQK 2169
Query: 148 LQSMAILGKATSHTQAVLQKTMEQNRSL----EKEINALQWEIEFDHNRFKNIEESWIQK 203
++ G + + L+ ++ R EKEI L+ ++E +N E Q
Sbjct: 2170 VEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQL 2229
Query: 204 YDRLNCENAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAM 245
+ +L + L+ +E K+ K D L E+ AM
Sbjct: 2230 HMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAM 2271
Score = 37.7 bits (86), Expect = 0.025
Identities = 80/416 (19%), Positives = 158/416 (37%), Gaps = 73/416 (17%)
Query: 69 RNEASFQYSKHKSQQDTFPQVSRISNYRRQSSTVDSNSELSNEELRQCLNETLEEVEMLK 128
R + + + SK + D + + + Q T D L E L C + L+E+E +
Sbjct: 1910 REQLAVELSKAEGVIDGYADEKTLFERQIQEKT-DIIDRLEQELL--CASNRLQELEAEQ 1966
Query: 129 TELEASQRQLRGKEEALK---------ILQSMAILGKATSHTQAVLQKTMEQNRSLEKEI 179
+++ + L ++EA+K +LQ L K Q +K + L+K++
Sbjct: 1967 QQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDD---LQKQV 2023
Query: 180 NALQWEIEFDHNRFKNIE-----------------ESWIQKYDRLNCENAV--------- 213
AL+ ++E +RF +E E ++K + E A+
Sbjct: 2024 KALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVF 2083
Query: 214 ------LKENLKV----------KTEEIKMLKSDNAVLNQRYLEALAMLDIKQQKMAQEN 257
L++ LKV +T E++ L + + E L + Q+ + + N
Sbjct: 2084 QQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERN 2143
Query: 258 MCCDKSGFAEASGLELAVLGACLCHGPGGNPCSCARMAASTRKLLLQLKQELEILQKSKE 317
+K F + ++ A A A L +QL+ E + + + ++
Sbjct: 2144 EEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEK 2203
Query: 318 EAYVMADAFRIAFEQQLMRKNDQALQL-TQMDKMHKKATKWMNWKHLKEDGFPSPRSKKT 376
E + + F ++L KN++ QL Q++ K++T + + F K
Sbjct: 2204 EITNLEEQLE-QFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEK-- 2260
Query: 377 FGQRLLGMLPSENSSKRMEDQD-------SPQEVLKMLIDLLNDKEEALAHQRKVS 425
LG+ E+ + +DQ + ++ ID LN++ L Q K++
Sbjct: 2261 -----LGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKIT 2311
Score = 34.3 bits (77), Expect = 0.28
Identities = 41/193 (21%), Positives = 88/193 (45%), Gaps = 14/193 (7%)
Query: 68 ERNEASFQYSKHKSQQDTFPQVSRISNYRRQSSTVDSNSELSNEELRQCLNETLE-EVEM 126
++N+ + SK K Q + S+ Q + + E+ +E ++ TLE EV+
Sbjct: 691 KQNQLILEISKLKDLQQSLVN-SKSEEMTLQINELQKEIEILRQEEKE--KGTLEQEVQE 747
Query: 127 LKTELEASQRQLRGKEEALKILQSMAILGKATSHTQAVLQKTMEQNRSLEKEINALQWEI 186
L+ + E ++Q++ KE L+ + A L +A + +KT+E + ++ + I
Sbjct: 748 LQLKTELLEKQMKEKENDLQ--EKFAQL-EAENSILKDEKKTLEDMLKIHTPVSQEERLI 804
Query: 187 EFDHNRFKNIEESWIQKYDRLNCENAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAML 246
D + K+ + W ++ + L EN LK+ EEI+ ++ + + +
Sbjct: 805 FLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNF------- 857
Query: 247 DIKQQKMAQENMC 259
++ Q++ +E C
Sbjct: 858 EVNYQELQEEYAC 870
Score = 32.7 bits (73), Expect = 0.81
Identities = 38/119 (31%), Positives = 55/119 (46%), Gaps = 18/119 (15%)
Query: 105 NSELSNEELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQAV 164
NS L +E+ +TLE+ MLK SQ EE L L S+ K S +
Sbjct: 777 NSILKDEK------KTLED--MLKIHTPVSQ------EERLIFLDSIKSKSK-DSVWEKE 821
Query: 165 LQKTMEQNRSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLKENLKVKTE 223
++ +E+N L+++ L EIE N F E+++ Y L E A L LKVK +
Sbjct: 822 IEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACL---LKVKDD 877
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 46.6 bits (109), Expect = 5e-05
Identities = 37/168 (22%), Positives = 75/168 (44%), Gaps = 9/168 (5%)
Query: 69 RNEASFQYSKHKSQQDTFPQVSRISNYRRQSSTVDSNSELSNEELRQCLNETLEEVEMLK 128
R + F + + S+ ++ N + + + + + L+ +++ +E ++ K
Sbjct: 626 RTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEK 685
Query: 129 TELEASQRQLRGKEEALKILQSMAILGKATSHTQAV--LQKTME-------QNRSLEKEI 179
L Q QL + LK LQ + K+ T + LQK +E + +LE+E+
Sbjct: 686 DNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEV 745
Query: 180 NALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLKENLKVKTEEIKM 227
LQ + E + K E +K+ +L EN++LK+ K + +K+
Sbjct: 746 QELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKI 793
Score = 40.4 bits (93), Expect = 0.004
Identities = 38/162 (23%), Positives = 74/162 (45%), Gaps = 12/162 (7%)
Query: 88 QVSRISNYRRQSSTVDSNSELSNEELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKI 147
+V +++N+ ++ + S LS E+L++ + E EE+E L + ++R E+AL +
Sbjct: 2110 EVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKL-------EFRVRELEQAL-L 2161
Query: 148 LQSMAILGKATSHTQAVLQKTMEQNRSL----EKEINALQWEIEFDHNRFKNIEESWIQK 203
++ G + + L+ ++ R EKEI L+ ++E +N E Q
Sbjct: 2162 VEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQL 2221
Query: 204 YDRLNCENAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAM 245
+ +L + L+ +E K+ K D L E+ AM
Sbjct: 2222 HMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAM 2263
Score = 38.1 bits (87), Expect = 0.019
Identities = 84/416 (20%), Positives = 160/416 (38%), Gaps = 81/416 (19%)
Query: 69 RNEASFQYSKHKSQQDTFPQVSRISNYRRQSSTVDSNSELSNEELRQCLNETLEEVEMLK 128
R + + + SK + D + + + Q T D L E L C + L+E+E +
Sbjct: 1910 REQLAVELSKAEGVIDGYADEKTLFERQIQEKT-DIIDRLEQELL--CASNRLQELEAEQ 1966
Query: 129 TELEASQRQLRGKEEALK---------ILQSMAILGKATSHTQAVLQKTMEQNRSLEKEI 179
+++ + L ++EA+K +LQ L K Q +K + L+K++
Sbjct: 1967 QQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDD---LQKQV 2023
Query: 180 NALQWEIEFDHNRFKNIE-----------------ESWIQKYDRLNCENAV--------- 213
AL+ ++E +RF +E E ++K + E A+
Sbjct: 2024 KALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVF 2083
Query: 214 ------LKENLKV----------KTEEIKMLKSDNAVLNQRYLEALAMLDIKQQKMAQEN 257
L++ LKV +T E++ L + + E L + Q+ + + N
Sbjct: 2084 QQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERN 2143
Query: 258 MCCDKSGFAEASGLELAVLGACLCHGPGGNPCSCARMAASTRKLLLQLKQELEILQKSKE 317
+K F LE A+L H A A L +QL+ E + + + ++
Sbjct: 2144 EEIEKLEF-RVRELEQALLVEDRKH-------FGAVEAKPELSLEVQLQAERDAIDRKEK 2195
Query: 318 EAYVMADAFRIAFEQQLMRKNDQALQL-TQMDKMHKKATKWMNWKHLKEDGFPSPRSKKT 376
E + + F ++L KN++ QL Q++ K++T + + F K
Sbjct: 2196 EITNLEEQLE-QFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEK-- 2252
Query: 377 FGQRLLGMLPSENSSKRMEDQD-------SPQEVLKMLIDLLNDKEEALAHQRKVS 425
LG+ E+ + +DQ + ++ ID LN++ L Q K++
Sbjct: 2253 -----LGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKIT 2303
Score = 34.3 bits (77), Expect = 0.28
Identities = 41/193 (21%), Positives = 88/193 (45%), Gaps = 14/193 (7%)
Query: 68 ERNEASFQYSKHKSQQDTFPQVSRISNYRRQSSTVDSNSELSNEELRQCLNETLE-EVEM 126
++N+ + SK K Q + S+ Q + + E+ +E ++ TLE EV+
Sbjct: 691 KQNQLILEISKLKDLQQSLVN-SKSEEMTLQINELQKEIEILRQEEKE--KGTLEQEVQE 747
Query: 127 LKTELEASQRQLRGKEEALKILQSMAILGKATSHTQAVLQKTMEQNRSLEKEINALQWEI 186
L+ + E ++Q++ KE L+ + A L +A + +KT+E + ++ + I
Sbjct: 748 LQLKTELLEKQMKEKENDLQ--EKFAQL-EAENSILKDEKKTLEDMLKIHTPVSQEERLI 804
Query: 187 EFDHNRFKNIEESWIQKYDRLNCENAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAML 246
D + K+ + W ++ + L EN LK+ EEI+ ++ + + +
Sbjct: 805 FLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNF------- 857
Query: 247 DIKQQKMAQENMC 259
++ Q++ +E C
Sbjct: 858 EVNYQELQEEYAC 870
Score = 32.7 bits (73), Expect = 0.81
Identities = 38/119 (31%), Positives = 55/119 (46%), Gaps = 18/119 (15%)
Query: 105 NSELSNEELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQAV 164
NS L +E+ +TLE+ MLK SQ EE L L S+ K S +
Sbjct: 777 NSILKDEK------KTLED--MLKIHTPVSQ------EERLIFLDSIKSKSK-DSVWEKE 821
Query: 165 LQKTMEQNRSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLKENLKVKTE 223
++ +E+N L+++ L EIE N F E+++ Y L E A L LKVK +
Sbjct: 822 IEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACL---LKVKDD 877
>gi|210032790 hypothetical protein LOC27146 [Homo sapiens]
Length = 1060
Score = 45.4 bits (106), Expect = 1e-04
Identities = 68/306 (22%), Positives = 129/306 (42%), Gaps = 49/306 (16%)
Query: 68 ERNEASFQYSKHKSQQDTFPQVSRI----SNYRRQSSTVDSNSELSNEELRQCLNETLEE 123
+R E +Q K K Q + SNYR + S+L E+L++ L ET ++
Sbjct: 592 QRLEEDWQSQKAKLQAQVSQMQQALEQCTSNYREDLQALKQLSDLEREKLQRELQETTQQ 651
Query: 124 VEMLKTELEAS-QRQLRGKEEA--LKILQSMAILGKATSHTQAVLQKTMEQNRSLEKEIN 180
+K +LEAS QR LR E+A ++ + L K +SH+ + Q+++ E+
Sbjct: 652 NHAMKAQLEASHQRALRMLEKARHQELKATEERLKKESSHSLQI------QHQTHRLELQ 705
Query: 181 ALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLKENLKVKTEE-----------IKMLK 229
AL+ + + ++ +R+ + A+L E+L+ + E ++ L+
Sbjct: 706 ALE----------EKARQELQEERERMQAQQALLLESLRQELSEQQAACSGHQKDLEALQ 755
Query: 230 SDNAVLNQRYLEALAMLDIKQQKMAQENMCCDKSGFAEASGLELAVLGACLCHGPG-GNP 288
++ L ++ + D K +A E ++ G +A A G G G
Sbjct: 756 AELRALGRQQASSQCPGDSKDHIIATE----ERGGPGQAGSPPGAA-------GQGSGEG 804
Query: 289 CSCARMAASTRKLLLQLKQELEILQKSKEEAYVMADAFRIAFEQQLMRKNDQALQLTQMD 348
C A + + +L+ E+E + ++EA + D R E Q ++ + L Q
Sbjct: 805 CGLWEENAQLQDAVRRLRAEVE---QHQQEAQKLRDQRRFLEETQQAQRAREVETLRQEH 861
Query: 349 KMHKKA 354
+ +A
Sbjct: 862 RKEMQA 867
Score = 37.4 bits (85), Expect = 0.033
Identities = 77/419 (18%), Positives = 157/419 (37%), Gaps = 64/419 (15%)
Query: 63 PRKGEERNEASFQYSKHKSQQDTFPQVSRISNYRRQSSTVDSNSELSNEELRQCLNETLE 122
P +G E E + + + + Q+S+ +Y R++ + + E NE +RQ + +++
Sbjct: 187 PGQGPEMQEVLLEVQRLRVENQ---QLSK--DYARKAEELQATYERENEAIRQAMQQSVS 241
Query: 123 EVEMLKTELEASQRQ-LRGKEEAL-----KILQSMAILGKATSHTQAVLQKTMEQNRSLE 176
+ E E+ R+ + +E AL K+ + G+ S + QK E+ + L+
Sbjct: 242 QALWQWQEKESDLRKNFQVQESALQAQVRKLEGDLEHRGRKISDLKKYAQKLKERIQDLD 301
Query: 177 KEINALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLKENLKVKTEEIKMLKSDNAVLN 236
++ + EN+ LK K E++ + K D +L
Sbjct: 302 VQLKEARQ-------------------------ENSELKGTAKKLGEKLAVAK-DRMMLQ 335
Query: 237 QRYLEALAMLDIKQQKMAQENMCCDKSGFAEASGL----ELAVLGACLCHGPGGNPCSCA 292
+ D + ++ EN + EA L + + L C C G + +
Sbjct: 336 E--CRGTQQTDAMKTELVSENKVLREENDLEAGNLHPQQDQSCLKECPCMKGGTDMQTKK 393
Query: 293 RMAASTRKLLLQLKQEL-EILQKSKEEAYVMADAFRIAFEQ----------------QLM 335
+A T + Q +++L +I +++EE + D E +
Sbjct: 394 EASAETEYMKQQYEEDLRKIKHQTEEEKKHLKDQLVKRLEDLVKKHTVEIKSVRSSVEAE 453
Query: 336 RKNDQALQLTQMDKMHKKATKWMNWKHLKEDGFPSPRSKKTFGQRLLGMLPSENSSKRME 395
RK Q Q++++ KK+ K + ++ L +N ++
Sbjct: 454 RKKLQREVEAQLEEVRKKSEKEIKQLEEEKAALNVKLQNSLLEVLRLEEFIQQNKTRPTG 513
Query: 396 DQDSPQEVLKMLIDLLNDKEEAL----AHQRKVSYMLARALEDKDTASNENKEKNPIKE 450
++SPQE+ + +L ++ L R Y A E+ ++ E + K +KE
Sbjct: 514 AEESPQELGRQHCSILETQDPCLKLDETSPRGEEYQDKLAAEEGTSSDEEERTKVLLKE 572
Score = 30.0 bits (66), Expect = 5.2
Identities = 32/165 (19%), Positives = 69/165 (41%), Gaps = 12/165 (7%)
Query: 100 STVDSNSELSNEELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATS 159
+T +E S E LR+ E L+ + +T+ Q Q +EEAL LQ + L A
Sbjct: 53 NTRQDEAEASMEALREAHQEELQNA-VAETKARLLQEQGCAEEEAL--LQRIQALESALE 109
Query: 160 HTQAVLQKTMEQNRSLEKEINALQWEIEFDH--------NRFKNIEESWIQKYDRLNCEN 211
+ + ++ + ++ S E + +E +H ++ + ++ L
Sbjct: 110 LQKRLTEEALAESASCRLETKERELRVEAEHAERVLTLSREMLELKADYERRLQHLTSHE 169
Query: 212 AVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAMLDIKQQKMAQE 256
A + L ++ E K + + LE + L ++ Q+++++
Sbjct: 170 ATPQGRLPQESPETKSEPGQGPEMQEVLLE-VQRLRVENQQLSKD 213
>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
[Homo sapiens]
Length = 1354
Score = 45.1 bits (105), Expect = 2e-04
Identities = 89/449 (19%), Positives = 169/449 (37%), Gaps = 82/449 (18%)
Query: 62 FPRKGEERNEASFQYSKHKSQQDTFPQVSRISNYRRQSSTVDSNSELSNEELRQCLNETL 121
+ RK E+ NE +++ +VS + + V NS+L+NE+L Q +
Sbjct: 498 YQRKAEQENE---------KRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLE 548
Query: 122 EEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQAVLQKTMEQN--------- 172
E ++L+TE + + R + E K + + L + +L+ + Q
Sbjct: 549 EANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDYYQLQA 608
Query: 173 ----------------RSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLN-----CEN 211
L+ I +LQ E++ + + +E + D LN N
Sbjct: 609 ILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNN 668
Query: 212 AVLKENLKVKT------EEIKMLKSDNAVLNQRY-----LEALAMLD----IKQQKMAQ- 255
+ N K+K+ +E+ K A L ++ +++AM + +K+++ A+
Sbjct: 669 LEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREARE 728
Query: 256 --ENMCCDKSGFAEASGLELAVLGACLCHGPGGNPCSCARMAASTRKLLLQLKQELE--- 310
EN ++L L H G RM + L LQL+QE
Sbjct: 729 KAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNK----ERMEDEVKNLTLQLEQESNKRL 784
Query: 311 ILQKSKEEAYVMADAFRIAFEQQLMRKNDQALQLTQMDKMHKKATKWMNWKHLKEDGFPS 370
+LQ + AD + E+Q+ ++ + L+ ++ + + + E
Sbjct: 785 LLQNELKTQAFEADNLK-GLEKQMKQEINTLLEAKRL--LEFELAQLTKQYRGNEGQMRE 841
Query: 371 PRSKKTFGQRLLGMLPSENSSKRMEDQDSPQEVLKMLIDLLNDKEEA-----LAHQRKVS 425
+ + Q + ++ + E ++ +E LK + +L N+KE LA + S
Sbjct: 842 LQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKAES 901
Query: 426 YMLARAL----------EDKDTASNENKE 444
LAR L E K AS +E
Sbjct: 902 EQLARGLLEEQYFELTQESKKAASRNRQE 930
Score = 35.8 bits (81), Expect = 0.095
Identities = 33/154 (21%), Positives = 68/154 (44%), Gaps = 17/154 (11%)
Query: 94 NYRRQSSTVDSNSELSNEELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKILQSMAI 153
N R SS D + + S ++ L E L LK E+E R K + KI++ +
Sbjct: 412 NDNRTSSNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLD--KIMKELDE 469
Query: 154 LGKATSHTQAVLQKTMEQNRSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNCENAV 213
G + ++ + + ++ L+ IN Q + E ++ + +N+E E +
Sbjct: 470 EGNQRRNLESTVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVEN-----------EVST 518
Query: 214 LKENLKVKTEEIKMLKSDNAVLNQRYLEALAMLD 247
LK+ L E++K + ++ + N++ + L+
Sbjct: 519 LKDQL----EDLKKVSQNSQLANEKLSQLQKQLE 548
Score = 32.7 bits (73), Expect = 0.81
Identities = 33/151 (21%), Positives = 64/151 (42%), Gaps = 17/151 (11%)
Query: 95 YRRQSSTVDSNSELSNEELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKILQSMAI- 153
Y+ Q + E N E + + E E E L T+L+ ++ + ++ A +L+
Sbjct: 856 YKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFE 915
Query: 154 ----LGKATSHTQA-------VLQKTMEQNRSLEKEINALQWEIEFDHNRFKNIEESW-I 201
KA S + + + E N L K+I L+ E E + K EE + +
Sbjct: 916 LTQESKKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMKKAEEEYKL 975
Query: 202 QKYDRLNCENAVLKENLK----VKTEEIKML 228
+K + ++ A ++N+ +KT+ + L
Sbjct: 976 EKEEEISNLKAAFEKNINTERTLKTQAVNKL 1006
Score = 29.6 bits (65), Expect = 6.8
Identities = 17/65 (26%), Positives = 32/65 (49%)
Query: 387 SENSSKRMEDQDSPQEVLKMLIDLLNDKEEALAHQRKVSYMLARALEDKDTASNENKEKN 446
S+NS E Q+ L+ DLL + + RK +++++ ++ + E +E+N
Sbjct: 530 SQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERN 589
Query: 447 PIKEN 451
I EN
Sbjct: 590 RILEN 594
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 45.1 bits (105), Expect = 2e-04
Identities = 79/367 (21%), Positives = 146/367 (39%), Gaps = 47/367 (12%)
Query: 96 RRQSSTVDSNSELSNEELRQCLNETLEEVEMLKTELEASQR-QLRGKEEALKILQ----- 149
RR++ S + EE + LEEVE LK ++E ++R + R ++E+ + LQ
Sbjct: 1983 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2042
Query: 150 -SMAILGKATSHTQAVLQKTMEQNRSLEKE---INALQWEIEFDHNRFKNIEESWIQKYD 205
+ + +H AV QK E ++L++E ++ L+ E E + EE+
Sbjct: 2043 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEA------ 2096
Query: 206 RLNCENAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAMLDIKQQKMAQENMCCDKSGF 265
R+ E + +V EE + LK Q +A A + +++ QE +
Sbjct: 2097 RVQAEREAAQSRRQV--EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQE---AARRAQ 2151
Query: 266 AEASGLELAVLGACLCHGPGGNPCSCARMAASTRKLLLQLKQELEILQKSKEEAYVMADA 325
AE + L + A T + Q++QEL L
Sbjct: 2152 AEQAALRQK-------QAADAEMEKHKKFAEQTLRQKAQVEQELTTL------------- 2191
Query: 326 FRIAFEQQLMRKNDQALQLTQMDKMHKKATKWMNWKHLKEDGFPSPRSKKTFGQRLLGML 385
R+ E+ +KN L ++ ++ +AT+ + E+ S R + +L +
Sbjct: 2192 -RLQLEETDHQKN---LLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARI 2247
Query: 386 PSENSSKRMEDQDSPQEVLKMLIDLLNDKEEALAHQRKVSYMLA--RALEDKDTASNENK 443
+EN + + D+D+ Q L+ + + E A + A R L ++D A
Sbjct: 2248 EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2307
Query: 444 EKNPIKE 450
+ +KE
Sbjct: 2308 AEKMLKE 2314
Score = 34.3 bits (77), Expect = 0.28
Identities = 49/228 (21%), Positives = 94/228 (41%), Gaps = 29/228 (12%)
Query: 64 RKGEERNEASFQYSKHKSQ-QDTFPQVSRISNYRRQSSTVDSNSELSNEELR-----QCL 117
R EE EA Q + +Q + + R+ + + + ++ + E+LR +
Sbjct: 2088 RAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAA 2147
Query: 118 NETLEEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQAVLQKTMEQNRSLEK 177
E L+ + A + K+ A + L+ A + + + + L++T Q L++
Sbjct: 2148 RRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDE 2207
Query: 178 EINALQWEIEFDHNRFKNIEESW----IQKYD------RLNCENAVL----KEN----LK 219
E+ L+ E + +EE +Q + R+ EN L K+N L+
Sbjct: 2208 ELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQ 2267
Query: 220 VKTEEIKMLKSDNAVLNQRYLEA-----LAMLDIKQQKMAQENMCCDK 262
+ E++K + + A L+ EA LA D+ QQ+ E M +K
Sbjct: 2268 EEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEK 2315
Score = 33.9 bits (76), Expect = 0.36
Identities = 37/176 (21%), Positives = 77/176 (43%), Gaps = 19/176 (10%)
Query: 97 RQSSTVDSNSELSNEELRQCLNETLEE-VEMLKTELEASQRQLRGKEEALKILQSMAILG 155
RQSS + ++ E + +EE + +++ +LEA++RQ G E L+ L++ A
Sbjct: 1426 RQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARA--- 1482
Query: 156 KATSHTQAVLQKTMEQNRSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLK 215
++ Q R ++E L+ +++ D ++ K E + + E A K
Sbjct: 1483 ----------EEAEAQKRQAQEEAERLRRQVQ-DESQRKRQAEVELASRVKAEAEAAREK 1531
Query: 216 ENLKVKTEEIKMLKSD-NAVLNQRYLEALAMLDI---KQQKMAQENMCCDKSGFAE 267
+ EE+++ + L Q +E + + Q+ A+ + ++ FAE
Sbjct: 1532 QRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE 1587
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 45.1 bits (105), Expect = 2e-04
Identities = 79/367 (21%), Positives = 146/367 (39%), Gaps = 47/367 (12%)
Query: 96 RRQSSTVDSNSELSNEELRQCLNETLEEVEMLKTELEASQR-QLRGKEEALKILQ----- 149
RR++ S + EE + LEEVE LK ++E ++R + R ++E+ + LQ
Sbjct: 1987 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2046
Query: 150 -SMAILGKATSHTQAVLQKTMEQNRSLEKE---INALQWEIEFDHNRFKNIEESWIQKYD 205
+ + +H AV QK E ++L++E ++ L+ E E + EE+
Sbjct: 2047 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEA------ 2100
Query: 206 RLNCENAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAMLDIKQQKMAQENMCCDKSGF 265
R+ E + +V EE + LK Q +A A + +++ QE +
Sbjct: 2101 RVQAEREAAQSRRQV--EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQE---AARRAQ 2155
Query: 266 AEASGLELAVLGACLCHGPGGNPCSCARMAASTRKLLLQLKQELEILQKSKEEAYVMADA 325
AE + L + A T + Q++QEL L
Sbjct: 2156 AEQAALRQK-------QAADAEMEKHKKFAEQTLRQKAQVEQELTTL------------- 2195
Query: 326 FRIAFEQQLMRKNDQALQLTQMDKMHKKATKWMNWKHLKEDGFPSPRSKKTFGQRLLGML 385
R+ E+ +KN L ++ ++ +AT+ + E+ S R + +L +
Sbjct: 2196 -RLQLEETDHQKN---LLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARI 2251
Query: 386 PSENSSKRMEDQDSPQEVLKMLIDLLNDKEEALAHQRKVSYMLA--RALEDKDTASNENK 443
+EN + + D+D+ Q L+ + + E A + A R L ++D A
Sbjct: 2252 EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2311
Query: 444 EKNPIKE 450
+ +KE
Sbjct: 2312 AEKMLKE 2318
Score = 34.3 bits (77), Expect = 0.28
Identities = 49/228 (21%), Positives = 94/228 (41%), Gaps = 29/228 (12%)
Query: 64 RKGEERNEASFQYSKHKSQ-QDTFPQVSRISNYRRQSSTVDSNSELSNEELR-----QCL 117
R EE EA Q + +Q + + R+ + + + ++ + E+LR +
Sbjct: 2092 RAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAA 2151
Query: 118 NETLEEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQAVLQKTMEQNRSLEK 177
E L+ + A + K+ A + L+ A + + + + L++T Q L++
Sbjct: 2152 RRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDE 2211
Query: 178 EINALQWEIEFDHNRFKNIEESW----IQKYD------RLNCENAVL----KEN----LK 219
E+ L+ E + +EE +Q + R+ EN L K+N L+
Sbjct: 2212 ELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQ 2271
Query: 220 VKTEEIKMLKSDNAVLNQRYLEA-----LAMLDIKQQKMAQENMCCDK 262
+ E++K + + A L+ EA LA D+ QQ+ E M +K
Sbjct: 2272 EEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEK 2319
Score = 33.9 bits (76), Expect = 0.36
Identities = 37/176 (21%), Positives = 77/176 (43%), Gaps = 19/176 (10%)
Query: 97 RQSSTVDSNSELSNEELRQCLNETLEE-VEMLKTELEASQRQLRGKEEALKILQSMAILG 155
RQSS + ++ E + +EE + +++ +LEA++RQ G E L+ L++ A
Sbjct: 1430 RQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARA--- 1486
Query: 156 KATSHTQAVLQKTMEQNRSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLK 215
++ Q R ++E L+ +++ D ++ K E + + E A K
Sbjct: 1487 ----------EEAEAQKRQAQEEAERLRRQVQ-DESQRKRQAEVELASRVKAEAEAAREK 1535
Query: 216 ENLKVKTEEIKMLKSD-NAVLNQRYLEALAMLDI---KQQKMAQENMCCDKSGFAE 267
+ EE+++ + L Q +E + + Q+ A+ + ++ FAE
Sbjct: 1536 QRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE 1591
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 45.1 bits (105), Expect = 2e-04
Identities = 79/367 (21%), Positives = 146/367 (39%), Gaps = 47/367 (12%)
Query: 96 RRQSSTVDSNSELSNEELRQCLNETLEEVEMLKTELEASQR-QLRGKEEALKILQ----- 149
RR++ S + EE + LEEVE LK ++E ++R + R ++E+ + LQ
Sbjct: 1983 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2042
Query: 150 -SMAILGKATSHTQAVLQKTMEQNRSLEKE---INALQWEIEFDHNRFKNIEESWIQKYD 205
+ + +H AV QK E ++L++E ++ L+ E E + EE+
Sbjct: 2043 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEA------ 2096
Query: 206 RLNCENAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAMLDIKQQKMAQENMCCDKSGF 265
R+ E + +V EE + LK Q +A A + +++ QE +
Sbjct: 2097 RVQAEREAAQSRRQV--EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQE---AARRAQ 2151
Query: 266 AEASGLELAVLGACLCHGPGGNPCSCARMAASTRKLLLQLKQELEILQKSKEEAYVMADA 325
AE + L + A T + Q++QEL L
Sbjct: 2152 AEQAALRQK-------QAADAEMEKHKKFAEQTLRQKAQVEQELTTL------------- 2191
Query: 326 FRIAFEQQLMRKNDQALQLTQMDKMHKKATKWMNWKHLKEDGFPSPRSKKTFGQRLLGML 385
R+ E+ +KN L ++ ++ +AT+ + E+ S R + +L +
Sbjct: 2192 -RLQLEETDHQKN---LLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARI 2247
Query: 386 PSENSSKRMEDQDSPQEVLKMLIDLLNDKEEALAHQRKVSYMLA--RALEDKDTASNENK 443
+EN + + D+D+ Q L+ + + E A + A R L ++D A
Sbjct: 2248 EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2307
Query: 444 EKNPIKE 450
+ +KE
Sbjct: 2308 AEKMLKE 2314
Score = 34.3 bits (77), Expect = 0.28
Identities = 49/228 (21%), Positives = 94/228 (41%), Gaps = 29/228 (12%)
Query: 64 RKGEERNEASFQYSKHKSQ-QDTFPQVSRISNYRRQSSTVDSNSELSNEELR-----QCL 117
R EE EA Q + +Q + + R+ + + + ++ + E+LR +
Sbjct: 2088 RAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAA 2147
Query: 118 NETLEEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQAVLQKTMEQNRSLEK 177
E L+ + A + K+ A + L+ A + + + + L++T Q L++
Sbjct: 2148 RRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDE 2207
Query: 178 EINALQWEIEFDHNRFKNIEESW----IQKYD------RLNCENAVL----KEN----LK 219
E+ L+ E + +EE +Q + R+ EN L K+N L+
Sbjct: 2208 ELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQ 2267
Query: 220 VKTEEIKMLKSDNAVLNQRYLEA-----LAMLDIKQQKMAQENMCCDK 262
+ E++K + + A L+ EA LA D+ QQ+ E M +K
Sbjct: 2268 EEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEK 2315
Score = 33.9 bits (76), Expect = 0.36
Identities = 37/176 (21%), Positives = 77/176 (43%), Gaps = 19/176 (10%)
Query: 97 RQSSTVDSNSELSNEELRQCLNETLEE-VEMLKTELEASQRQLRGKEEALKILQSMAILG 155
RQSS + ++ E + +EE + +++ +LEA++RQ G E L+ L++ A
Sbjct: 1426 RQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARA--- 1482
Query: 156 KATSHTQAVLQKTMEQNRSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLK 215
++ Q R ++E L+ +++ D ++ K E + + E A K
Sbjct: 1483 ----------EEAEAQKRQAQEEAERLRRQVQ-DESQRKRQAEVELASRVKAEAEAAREK 1531
Query: 216 ENLKVKTEEIKMLKSD-NAVLNQRYLEALAMLDI---KQQKMAQENMCCDKSGFAE 267
+ EE+++ + L Q +E + + Q+ A+ + ++ FAE
Sbjct: 1532 QRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE 1587
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 45.1 bits (105), Expect = 2e-04
Identities = 79/367 (21%), Positives = 146/367 (39%), Gaps = 47/367 (12%)
Query: 96 RRQSSTVDSNSELSNEELRQCLNETLEEVEMLKTELEASQR-QLRGKEEALKILQ----- 149
RR++ S + EE + LEEVE LK ++E ++R + R ++E+ + LQ
Sbjct: 1951 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2010
Query: 150 -SMAILGKATSHTQAVLQKTMEQNRSLEKE---INALQWEIEFDHNRFKNIEESWIQKYD 205
+ + +H AV QK E ++L++E ++ L+ E E + EE+
Sbjct: 2011 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEA------ 2064
Query: 206 RLNCENAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAMLDIKQQKMAQENMCCDKSGF 265
R+ E + +V EE + LK Q +A A + +++ QE +
Sbjct: 2065 RVQAEREAAQSRRQV--EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQE---AARRAQ 2119
Query: 266 AEASGLELAVLGACLCHGPGGNPCSCARMAASTRKLLLQLKQELEILQKSKEEAYVMADA 325
AE + L + A T + Q++QEL L
Sbjct: 2120 AEQAALRQK-------QAADAEMEKHKKFAEQTLRQKAQVEQELTTL------------- 2159
Query: 326 FRIAFEQQLMRKNDQALQLTQMDKMHKKATKWMNWKHLKEDGFPSPRSKKTFGQRLLGML 385
R+ E+ +KN L ++ ++ +AT+ + E+ S R + +L +
Sbjct: 2160 -RLQLEETDHQKN---LLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARI 2215
Query: 386 PSENSSKRMEDQDSPQEVLKMLIDLLNDKEEALAHQRKVSYMLA--RALEDKDTASNENK 443
+EN + + D+D+ Q L+ + + E A + A R L ++D A
Sbjct: 2216 EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2275
Query: 444 EKNPIKE 450
+ +KE
Sbjct: 2276 AEKMLKE 2282
Score = 34.3 bits (77), Expect = 0.28
Identities = 49/228 (21%), Positives = 94/228 (41%), Gaps = 29/228 (12%)
Query: 64 RKGEERNEASFQYSKHKSQ-QDTFPQVSRISNYRRQSSTVDSNSELSNEELR-----QCL 117
R EE EA Q + +Q + + R+ + + + ++ + E+LR +
Sbjct: 2056 RAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAA 2115
Query: 118 NETLEEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQAVLQKTMEQNRSLEK 177
E L+ + A + K+ A + L+ A + + + + L++T Q L++
Sbjct: 2116 RRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDE 2175
Query: 178 EINALQWEIEFDHNRFKNIEESW----IQKYD------RLNCENAVL----KEN----LK 219
E+ L+ E + +EE +Q + R+ EN L K+N L+
Sbjct: 2176 ELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQ 2235
Query: 220 VKTEEIKMLKSDNAVLNQRYLEA-----LAMLDIKQQKMAQENMCCDK 262
+ E++K + + A L+ EA LA D+ QQ+ E M +K
Sbjct: 2236 EEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEK 2283
Score = 33.9 bits (76), Expect = 0.36
Identities = 37/176 (21%), Positives = 77/176 (43%), Gaps = 19/176 (10%)
Query: 97 RQSSTVDSNSELSNEELRQCLNETLEE-VEMLKTELEASQRQLRGKEEALKILQSMAILG 155
RQSS + ++ E + +EE + +++ +LEA++RQ G E L+ L++ A
Sbjct: 1394 RQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARA--- 1450
Query: 156 KATSHTQAVLQKTMEQNRSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLK 215
++ Q R ++E L+ +++ D ++ K E + + E A K
Sbjct: 1451 ----------EEAEAQKRQAQEEAERLRRQVQ-DESQRKRQAEVELASRVKAEAEAAREK 1499
Query: 216 ENLKVKTEEIKMLKSD-NAVLNQRYLEALAMLDI---KQQKMAQENMCCDKSGFAE 267
+ EE+++ + L Q +E + + Q+ A+ + ++ FAE
Sbjct: 1500 QRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE 1555
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 45.1 bits (105), Expect = 2e-04
Identities = 79/367 (21%), Positives = 146/367 (39%), Gaps = 47/367 (12%)
Query: 96 RRQSSTVDSNSELSNEELRQCLNETLEEVEMLKTELEASQR-QLRGKEEALKILQ----- 149
RR++ S + EE + LEEVE LK ++E ++R + R ++E+ + LQ
Sbjct: 2120 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2179
Query: 150 -SMAILGKATSHTQAVLQKTMEQNRSLEKE---INALQWEIEFDHNRFKNIEESWIQKYD 205
+ + +H AV QK E ++L++E ++ L+ E E + EE+
Sbjct: 2180 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEA------ 2233
Query: 206 RLNCENAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAMLDIKQQKMAQENMCCDKSGF 265
R+ E + +V EE + LK Q +A A + +++ QE +
Sbjct: 2234 RVQAEREAAQSRRQV--EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQE---AARRAQ 2288
Query: 266 AEASGLELAVLGACLCHGPGGNPCSCARMAASTRKLLLQLKQELEILQKSKEEAYVMADA 325
AE + L + A T + Q++QEL L
Sbjct: 2289 AEQAALRQK-------QAADAEMEKHKKFAEQTLRQKAQVEQELTTL------------- 2328
Query: 326 FRIAFEQQLMRKNDQALQLTQMDKMHKKATKWMNWKHLKEDGFPSPRSKKTFGQRLLGML 385
R+ E+ +KN L ++ ++ +AT+ + E+ S R + +L +
Sbjct: 2329 -RLQLEETDHQKN---LLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARI 2384
Query: 386 PSENSSKRMEDQDSPQEVLKMLIDLLNDKEEALAHQRKVSYMLA--RALEDKDTASNENK 443
+EN + + D+D+ Q L+ + + E A + A R L ++D A
Sbjct: 2385 EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2444
Query: 444 EKNPIKE 450
+ +KE
Sbjct: 2445 AEKMLKE 2451
Score = 34.3 bits (77), Expect = 0.28
Identities = 49/228 (21%), Positives = 94/228 (41%), Gaps = 29/228 (12%)
Query: 64 RKGEERNEASFQYSKHKSQ-QDTFPQVSRISNYRRQSSTVDSNSELSNEELR-----QCL 117
R EE EA Q + +Q + + R+ + + + ++ + E+LR +
Sbjct: 2225 RAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAA 2284
Query: 118 NETLEEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQAVLQKTMEQNRSLEK 177
E L+ + A + K+ A + L+ A + + + + L++T Q L++
Sbjct: 2285 RRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDE 2344
Query: 178 EINALQWEIEFDHNRFKNIEESW----IQKYD------RLNCENAVL----KEN----LK 219
E+ L+ E + +EE +Q + R+ EN L K+N L+
Sbjct: 2345 ELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQ 2404
Query: 220 VKTEEIKMLKSDNAVLNQRYLEA-----LAMLDIKQQKMAQENMCCDK 262
+ E++K + + A L+ EA LA D+ QQ+ E M +K
Sbjct: 2405 EEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEK 2452
Score = 33.9 bits (76), Expect = 0.36
Identities = 37/176 (21%), Positives = 77/176 (43%), Gaps = 19/176 (10%)
Query: 97 RQSSTVDSNSELSNEELRQCLNETLEE-VEMLKTELEASQRQLRGKEEALKILQSMAILG 155
RQSS + ++ E + +EE + +++ +LEA++RQ G E L+ L++ A
Sbjct: 1563 RQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARA--- 1619
Query: 156 KATSHTQAVLQKTMEQNRSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLK 215
++ Q R ++E L+ +++ D ++ K E + + E A K
Sbjct: 1620 ----------EEAEAQKRQAQEEAERLRRQVQ-DESQRKRQAEVELASRVKAEAEAAREK 1668
Query: 216 ENLKVKTEEIKMLKSD-NAVLNQRYLEALAMLDI---KQQKMAQENMCCDKSGFAE 267
+ EE+++ + L Q +E + + Q+ A+ + ++ FAE
Sbjct: 1669 QRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE 1724
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 45.1 bits (105), Expect = 2e-04
Identities = 79/367 (21%), Positives = 146/367 (39%), Gaps = 47/367 (12%)
Query: 96 RRQSSTVDSNSELSNEELRQCLNETLEEVEMLKTELEASQR-QLRGKEEALKILQ----- 149
RR++ S + EE + LEEVE LK ++E ++R + R ++E+ + LQ
Sbjct: 1961 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2020
Query: 150 -SMAILGKATSHTQAVLQKTMEQNRSLEKE---INALQWEIEFDHNRFKNIEESWIQKYD 205
+ + +H AV QK E ++L++E ++ L+ E E + EE+
Sbjct: 2021 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEA------ 2074
Query: 206 RLNCENAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAMLDIKQQKMAQENMCCDKSGF 265
R+ E + +V EE + LK Q +A A + +++ QE +
Sbjct: 2075 RVQAEREAAQSRRQV--EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQE---AARRAQ 2129
Query: 266 AEASGLELAVLGACLCHGPGGNPCSCARMAASTRKLLLQLKQELEILQKSKEEAYVMADA 325
AE + L + A T + Q++QEL L
Sbjct: 2130 AEQAALRQK-------QAADAEMEKHKKFAEQTLRQKAQVEQELTTL------------- 2169
Query: 326 FRIAFEQQLMRKNDQALQLTQMDKMHKKATKWMNWKHLKEDGFPSPRSKKTFGQRLLGML 385
R+ E+ +KN L ++ ++ +AT+ + E+ S R + +L +
Sbjct: 2170 -RLQLEETDHQKN---LLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARI 2225
Query: 386 PSENSSKRMEDQDSPQEVLKMLIDLLNDKEEALAHQRKVSYMLA--RALEDKDTASNENK 443
+EN + + D+D+ Q L+ + + E A + A R L ++D A
Sbjct: 2226 EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2285
Query: 444 EKNPIKE 450
+ +KE
Sbjct: 2286 AEKMLKE 2292
Score = 34.3 bits (77), Expect = 0.28
Identities = 49/228 (21%), Positives = 94/228 (41%), Gaps = 29/228 (12%)
Query: 64 RKGEERNEASFQYSKHKSQ-QDTFPQVSRISNYRRQSSTVDSNSELSNEELR-----QCL 117
R EE EA Q + +Q + + R+ + + + ++ + E+LR +
Sbjct: 2066 RAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAA 2125
Query: 118 NETLEEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQAVLQKTMEQNRSLEK 177
E L+ + A + K+ A + L+ A + + + + L++T Q L++
Sbjct: 2126 RRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDE 2185
Query: 178 EINALQWEIEFDHNRFKNIEESW----IQKYD------RLNCENAVL----KEN----LK 219
E+ L+ E + +EE +Q + R+ EN L K+N L+
Sbjct: 2186 ELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQ 2245
Query: 220 VKTEEIKMLKSDNAVLNQRYLEA-----LAMLDIKQQKMAQENMCCDK 262
+ E++K + + A L+ EA LA D+ QQ+ E M +K
Sbjct: 2246 EEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEK 2293
Score = 33.9 bits (76), Expect = 0.36
Identities = 37/176 (21%), Positives = 77/176 (43%), Gaps = 19/176 (10%)
Query: 97 RQSSTVDSNSELSNEELRQCLNETLEE-VEMLKTELEASQRQLRGKEEALKILQSMAILG 155
RQSS + ++ E + +EE + +++ +LEA++RQ G E L+ L++ A
Sbjct: 1404 RQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARA--- 1460
Query: 156 KATSHTQAVLQKTMEQNRSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLK 215
++ Q R ++E L+ +++ D ++ K E + + E A K
Sbjct: 1461 ----------EEAEAQKRQAQEEAERLRRQVQ-DESQRKRQAEVELASRVKAEAEAAREK 1509
Query: 216 ENLKVKTEEIKMLKSD-NAVLNQRYLEALAMLDI---KQQKMAQENMCCDKSGFAE 267
+ EE+++ + L Q +E + + Q+ A+ + ++ FAE
Sbjct: 1510 QRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE 1565
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 45.1 bits (105), Expect = 2e-04
Identities = 79/367 (21%), Positives = 146/367 (39%), Gaps = 47/367 (12%)
Query: 96 RRQSSTVDSNSELSNEELRQCLNETLEEVEMLKTELEASQR-QLRGKEEALKILQ----- 149
RR++ S + EE + LEEVE LK ++E ++R + R ++E+ + LQ
Sbjct: 1969 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2028
Query: 150 -SMAILGKATSHTQAVLQKTMEQNRSLEKE---INALQWEIEFDHNRFKNIEESWIQKYD 205
+ + +H AV QK E ++L++E ++ L+ E E + EE+
Sbjct: 2029 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEA------ 2082
Query: 206 RLNCENAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAMLDIKQQKMAQENMCCDKSGF 265
R+ E + +V EE + LK Q +A A + +++ QE +
Sbjct: 2083 RVQAEREAAQSRRQV--EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQE---AARRAQ 2137
Query: 266 AEASGLELAVLGACLCHGPGGNPCSCARMAASTRKLLLQLKQELEILQKSKEEAYVMADA 325
AE + L + A T + Q++QEL L
Sbjct: 2138 AEQAALRQK-------QAADAEMEKHKKFAEQTLRQKAQVEQELTTL------------- 2177
Query: 326 FRIAFEQQLMRKNDQALQLTQMDKMHKKATKWMNWKHLKEDGFPSPRSKKTFGQRLLGML 385
R+ E+ +KN L ++ ++ +AT+ + E+ S R + +L +
Sbjct: 2178 -RLQLEETDHQKN---LLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARI 2233
Query: 386 PSENSSKRMEDQDSPQEVLKMLIDLLNDKEEALAHQRKVSYMLA--RALEDKDTASNENK 443
+EN + + D+D+ Q L+ + + E A + A R L ++D A
Sbjct: 2234 EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2293
Query: 444 EKNPIKE 450
+ +KE
Sbjct: 2294 AEKMLKE 2300
Score = 34.3 bits (77), Expect = 0.28
Identities = 49/228 (21%), Positives = 94/228 (41%), Gaps = 29/228 (12%)
Query: 64 RKGEERNEASFQYSKHKSQ-QDTFPQVSRISNYRRQSSTVDSNSELSNEELR-----QCL 117
R EE EA Q + +Q + + R+ + + + ++ + E+LR +
Sbjct: 2074 RAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAA 2133
Query: 118 NETLEEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQAVLQKTMEQNRSLEK 177
E L+ + A + K+ A + L+ A + + + + L++T Q L++
Sbjct: 2134 RRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDE 2193
Query: 178 EINALQWEIEFDHNRFKNIEESW----IQKYD------RLNCENAVL----KEN----LK 219
E+ L+ E + +EE +Q + R+ EN L K+N L+
Sbjct: 2194 ELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQ 2253
Query: 220 VKTEEIKMLKSDNAVLNQRYLEA-----LAMLDIKQQKMAQENMCCDK 262
+ E++K + + A L+ EA LA D+ QQ+ E M +K
Sbjct: 2254 EEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEK 2301
Score = 33.9 bits (76), Expect = 0.36
Identities = 37/176 (21%), Positives = 77/176 (43%), Gaps = 19/176 (10%)
Query: 97 RQSSTVDSNSELSNEELRQCLNETLEE-VEMLKTELEASQRQLRGKEEALKILQSMAILG 155
RQSS + ++ E + +EE + +++ +LEA++RQ G E L+ L++ A
Sbjct: 1412 RQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARA--- 1468
Query: 156 KATSHTQAVLQKTMEQNRSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLK 215
++ Q R ++E L+ +++ D ++ K E + + E A K
Sbjct: 1469 ----------EEAEAQKRQAQEEAERLRRQVQ-DESQRKRQAEVELASRVKAEAEAAREK 1517
Query: 216 ENLKVKTEEIKMLKSD-NAVLNQRYLEALAMLDI---KQQKMAQENMCCDKSGFAE 267
+ EE+++ + L Q +E + + Q+ A+ + ++ FAE
Sbjct: 1518 QRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE 1573
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 45.1 bits (105), Expect = 2e-04
Identities = 79/367 (21%), Positives = 146/367 (39%), Gaps = 47/367 (12%)
Query: 96 RRQSSTVDSNSELSNEELRQCLNETLEEVEMLKTELEASQR-QLRGKEEALKILQ----- 149
RR++ S + EE + LEEVE LK ++E ++R + R ++E+ + LQ
Sbjct: 2010 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2069
Query: 150 -SMAILGKATSHTQAVLQKTMEQNRSLEKE---INALQWEIEFDHNRFKNIEESWIQKYD 205
+ + +H AV QK E ++L++E ++ L+ E E + EE+
Sbjct: 2070 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEA------ 2123
Query: 206 RLNCENAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAMLDIKQQKMAQENMCCDKSGF 265
R+ E + +V EE + LK Q +A A + +++ QE +
Sbjct: 2124 RVQAEREAAQSRRQV--EEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQE---AARRAQ 2178
Query: 266 AEASGLELAVLGACLCHGPGGNPCSCARMAASTRKLLLQLKQELEILQKSKEEAYVMADA 325
AE + L + A T + Q++QEL L
Sbjct: 2179 AEQAALRQK-------QAADAEMEKHKKFAEQTLRQKAQVEQELTTL------------- 2218
Query: 326 FRIAFEQQLMRKNDQALQLTQMDKMHKKATKWMNWKHLKEDGFPSPRSKKTFGQRLLGML 385
R+ E+ +KN L ++ ++ +AT+ + E+ S R + +L +
Sbjct: 2219 -RLQLEETDHQKN---LLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARI 2274
Query: 386 PSENSSKRMEDQDSPQEVLKMLIDLLNDKEEALAHQRKVSYMLA--RALEDKDTASNENK 443
+EN + + D+D+ Q L+ + + E A + A R L ++D A
Sbjct: 2275 EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2334
Query: 444 EKNPIKE 450
+ +KE
Sbjct: 2335 AEKMLKE 2341
Score = 34.3 bits (77), Expect = 0.28
Identities = 49/228 (21%), Positives = 94/228 (41%), Gaps = 29/228 (12%)
Query: 64 RKGEERNEASFQYSKHKSQ-QDTFPQVSRISNYRRQSSTVDSNSELSNEELR-----QCL 117
R EE EA Q + +Q + + R+ + + + ++ + E+LR +
Sbjct: 2115 RAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAA 2174
Query: 118 NETLEEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQAVLQKTMEQNRSLEK 177
E L+ + A + K+ A + L+ A + + + + L++T Q L++
Sbjct: 2175 RRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDE 2234
Query: 178 EINALQWEIEFDHNRFKNIEESW----IQKYD------RLNCENAVL----KEN----LK 219
E+ L+ E + +EE +Q + R+ EN L K+N L+
Sbjct: 2235 ELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQ 2294
Query: 220 VKTEEIKMLKSDNAVLNQRYLEA-----LAMLDIKQQKMAQENMCCDK 262
+ E++K + + A L+ EA LA D+ QQ+ E M +K
Sbjct: 2295 EEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEK 2342
Score = 33.9 bits (76), Expect = 0.36
Identities = 37/176 (21%), Positives = 77/176 (43%), Gaps = 19/176 (10%)
Query: 97 RQSSTVDSNSELSNEELRQCLNETLEE-VEMLKTELEASQRQLRGKEEALKILQSMAILG 155
RQSS + ++ E + +EE + +++ +LEA++RQ G E L+ L++ A
Sbjct: 1453 RQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARA--- 1509
Query: 156 KATSHTQAVLQKTMEQNRSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLK 215
++ Q R ++E L+ +++ D ++ K E + + E A K
Sbjct: 1510 ----------EEAEAQKRQAQEEAERLRRQVQ-DESQRKRQAEVELASRVKAEAEAAREK 1558
Query: 216 ENLKVKTEEIKMLKSD-NAVLNQRYLEALAMLDI---KQQKMAQENMCCDKSGFAE 267
+ EE+++ + L Q +E + + Q+ A+ + ++ FAE
Sbjct: 1559 QRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE 1614
>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
Length = 2649
Score = 44.7 bits (104), Expect = 2e-04
Identities = 81/386 (20%), Positives = 155/386 (40%), Gaps = 71/386 (18%)
Query: 80 KSQQDTFPQVSRISNYRRQSSTVDSNS----ELSNEE----LRQCLNETLEEVEMLKTEL 131
K Q D +R + + T + N+ + S+EE L+ L+ET + LK EL
Sbjct: 1365 KQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLEL 1424
Query: 132 EASQRQLRGKEEALKILQSMAILGKATSHTQAVLQKTMEQNRSLEKEINALQWEIE-FDH 190
E + +G + L+ LG+ + T ++ M++ L+K Q E+E +H
Sbjct: 1425 ERKDQAEKGYSQQLR------ELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNH 1478
Query: 191 NRFKNIEESWIQKYDRLNCENAVLKENLKVKTEEIKMLKSDNAV----LNQRYLEALAML 246
+ K E DR+ +AV ++N++ +I + + + + QR + L
Sbjct: 1479 EKGKLQRE-----VDRITRAHAVAEKNIQHLNSQIHSFRDEKELERLQICQRKSDHLKEQ 1533
Query: 247 DIKQQKMAQENMCCDKSGFAEASGLELAVLGACLCHGPGGNPCSCARMAASTRKLLLQLK 306
K + +N+ +K + L + CA M LK
Sbjct: 1534 FEKSHEQLLQNIKAEKENNDKIQRLNEEL----------EKSNECAEM----------LK 1573
Query: 307 QELEILQKSKEEAYVM-----ADAFRIAFEQQLMRKNDQALQL----------TQMDKMH 351
Q++E L + E +M A++ I E+Q +++ +AL++ + + +H
Sbjct: 1574 QKVEELTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLH 1633
Query: 352 KKATKWMNW----KHLKEDGFPSPRSKKTFGQRLLGMLPSENSSKRMEDQDSPQEVLKML 407
K+ ++ K L+ED S Q L+ + + + Q++ +EV +
Sbjct: 1634 KQTKTEQDFQRKIKCLEEDLAKS--------QNLVSEFKQKCDQQNIIIQNTKKEVRNLN 1685
Query: 408 IDLLNDKEEALAHQRKVSYMLARALE 433
+L KEE ++KV A+ E
Sbjct: 1686 AELNASKEEKRRGEQKVQLQQAQVQE 1711
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 44.3 bits (103), Expect = 3e-04
Identities = 85/375 (22%), Positives = 155/375 (41%), Gaps = 51/375 (13%)
Query: 91 RISNYRRQSSTVDSNSE---LSNEELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKI 147
R S R + ++ +E +++E LRQ L E E L EL+A Q + KE+AL
Sbjct: 1286 RSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALST 1345
Query: 148 LQSMAILGKATSHTQAVLQKTMEQNRSLEKEINALQWEIEFDHNRFKNIEES-------- 199
LQ + TQA++ + + + L +++ A Q E H + +E+S
Sbjct: 1346 LQ------LEHTSTQALVSELLPA-KHLCQQLQAEQAAAEKRHR--EELEQSKQAAGGLR 1396
Query: 200 -WIQKYDRLNCENAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAMLDIKQQKMAQENM 258
+ + R E L++ + + + L+++ A Y E L+ML +A+EN
Sbjct: 1397 AELLRAQRELGELIPLRQKVAEQERTAQQLRAEKA----SYAEQLSMLKKAHGLLAEEN- 1451
Query: 259 CCDKSGFAEASGLELAVLGACLCHGPGGNPCSCARMAASTRKLLLQLK-------QELEI 311
G E + L L L A + A L +++ +ELE+
Sbjct: 1452 ----RGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEV 1507
Query: 312 LQKSKEEAYVMADAFRIAFEQQLMRKNDQAL--QLTQMDKMHKKATKWMNWKHLKEDGFP 369
+ E A V ++ E+Q ++ Q L Q+ Q++ ++ TK + + L +
Sbjct: 1508 MTAKYEGAKV-----KVLEERQRFQEERQKLTAQVEQLEVFQREQTKQV--EELSKKLAD 1560
Query: 370 SPRSKKTFGQRLLGMLPSENSSKRMEDQDSPQEVLKMLIDLLNDKEEALAHQRKVSYMLA 429
S ++ K Q+L + S+ ++ Q L L L+ KE+A H + +
Sbjct: 1561 SDQASKVQQQKLKAVQAQGGESQ--QEAQRLQAQLNELQAQLSQKEQAAEHYK---LQME 1615
Query: 430 RALEDKDTASNENKE 444
+A D +N+E
Sbjct: 1616 KAKTHYDAKKQQNQE 1630
Score = 38.9 bits (89), Expect = 0.011
Identities = 75/353 (21%), Positives = 140/353 (39%), Gaps = 47/353 (13%)
Query: 110 NEELRQCLNETLEEVEMLKTELEASQRQL------------RGKEEALKILQSMAILGKA 157
NE L L+ETL++ + LKTE R++ + +E A + Q L +
Sbjct: 285 NESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNEL 344
Query: 158 TSHTQAVLQKTMEQNRSLEKEINA-------LQWEIEFDHNRFKNIEESWIQKYDRLNCE 210
T Q+ +E+ LEKE++A L+ + E + +EE Q D E
Sbjct: 345 TEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQE 404
Query: 211 NA-VLKENLKVKT--EEIKMLKSDNAVLNQR---------YLEALAMLD---IKQQKMAQ 255
VL + L+++T +E L ++N L R EA + + +++K
Sbjct: 405 KGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQL 464
Query: 256 ENMCCD-KSGFAEASGLELAVLGACLCHGPGGNPCSCARMAASTRKLLLQLKQELEILQK 314
++ D +S + S + + A HG AR+ A L +L +Q+
Sbjct: 465 SSLITDLQSSISNLSQAKEELEQASQAHG--------ARLTAQVASLTSELTTLNATIQQ 516
Query: 315 SKEEAYVMADAFRIAFEQ--QLMRKNDQALQLTQMDKMHKKATKWMNWKHLKEDGFPSPR 372
+E + + Q Q +++ +QA Q + ++ + LKE
Sbjct: 517 QDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEA 576
Query: 373 SKKTFGQRLLGMLPSENSSKRMEDQDSPQEVLKMLIDLLNDKEEALAHQRKVS 425
+++ Q+L +E + ++D+ + L+ L K E L Q +V+
Sbjct: 577 TRQDHAQQL--ATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVA 627
Score = 34.3 bits (77), Expect = 0.28
Identities = 66/326 (20%), Positives = 126/326 (38%), Gaps = 51/326 (15%)
Query: 68 ERNEASFQYSKHKSQQDTFPQVSRISNYRRQSSTVDSNSELSNEELRQCLNETLEEVEML 127
E+ +S + + + ++ Q + ++ +Q +T E S E L + LE +E
Sbjct: 554 EQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQ-LEALEKE 612
Query: 128 KT-ELEASQRQLRGKEEALKILQSM--------AILGKATSHTQAVLQKTMEQNRSLEKE 178
K +LE Q+QL+ EA Q+ A L + QA ++ ++ + +
Sbjct: 613 KAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQ 672
Query: 179 INALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLKENLKV---KTEEIKMLKSDNAVL 235
+ L+ ++ + + +E Q+ D+L + LKE+LKV EE K +D
Sbjct: 673 VAELELQLRSEQQKATE-KERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEE 731
Query: 236 NQRYLEALAMLD---IKQQKMAQENMCCDKSG----------FAEASGLELAVLGACLCH 282
QR + L ++Q K ++ + +++G EA E VL L
Sbjct: 732 QQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAE 791
Query: 283 GPGGNPCS---C---------------------ARMAASTRKLLLQLKQELEILQKSKEE 318
+ C A+ A ++ L+ LK+E E ++ +E
Sbjct: 792 AMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQE 851
Query: 319 AYVMADAFRIAFEQQLMRKNDQALQL 344
A E Q+ R+ ++ +L
Sbjct: 852 AKEKVAGIESHSELQISRQQNELAEL 877
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 44.3 bits (103), Expect = 3e-04
Identities = 74/369 (20%), Positives = 152/369 (41%), Gaps = 52/369 (14%)
Query: 113 LRQCLNETLEEVEMLKTELEASQRQLR-----------GKEEALKILQSM---------- 151
L + L E + E ++ ELEA+QR+ R G EEAL+ L+++
Sbjct: 1498 LERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEE 1557
Query: 152 -AILGKATSHTQAVLQKTMEQNRSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNCE 210
+ L S + +Q+ + ++LE E + +Q +E + E ++ L+
Sbjct: 1558 ISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQV 1617
Query: 211 NAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAMLDIKQQKMAQENMCCDKSGFAEASG 270
A + L K EE L+ + +QR +E+L + + E + K + +
Sbjct: 1618 KAEVDRKLAEKDEECANLRRN----HQRAVESLQASLDAETRARNEALRLKKKMEGDLND 1673
Query: 271 LELAVLGACLCHGPGGNPCSCARMAASTRKLLLQLKQE---LEILQKSKEEAYVMADAFR 327
LEL + G A+TR + QLK+E + Q+ E + A A
Sbjct: 1674 LELQL---------GHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALE 1724
Query: 328 -----IAFEQQLMR----KNDQALQLTQMDKMHKKATKWMNWKHLKEDGFPSPRSKKTFG 378
+A E + +R + +++ +L + + + +AT+ +N H + G + + K
Sbjct: 1725 RRASLLAAELEELRAALEQGERSRRLAEQELL--EATERLNLLHSQNTGLLNQKKKLEAD 1782
Query: 379 QRLLGMLPSENSSKRMEDQDSPQEVL---KMLIDLLNDKEEALAHQRKVSYMLARALEDK 435
L E + +R E ++ ++ + M+ + L +++ AH ++ L + + +
Sbjct: 1783 LAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVREL 1842
Query: 436 DTASNENKE 444
E ++
Sbjct: 1843 QARLEEAEQ 1851
>gi|115495445 ankyrin repeat domain 30A [Homo sapiens]
Length = 1341
Score = 43.9 bits (102), Expect = 3e-04
Identities = 41/152 (26%), Positives = 74/152 (48%), Gaps = 22/152 (14%)
Query: 105 NSELSNEELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKI----LQSMAILGKATSH 160
N+++ NE++R+ L E+ + ELE Q+ E+AL+I L+S+ SH
Sbjct: 984 NADILNEKIREELGRIEEQH---RKELEVKQQL----EQALRIQDIELKSVESNLNQVSH 1036
Query: 161 TQAVLQKTMEQNRSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLKENLKV 220
T + +N L+KEI L+ EI ++++ E + + L +NA L+ LK+
Sbjct: 1037 THENENYLLHENCMLKKEIAMLKLEIATLKHQYQEKENKYFEDIKILKEKNAELQMTLKL 1096
Query: 221 KTE-----------EIKMLKSDNAVLNQRYLE 241
K E ++K+L ++N +L + E
Sbjct: 1097 KEESLTKRASQYSGQLKVLIAENTMLTSKLKE 1128
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 43.5 bits (101), Expect = 5e-04
Identities = 40/169 (23%), Positives = 75/169 (44%), Gaps = 18/169 (10%)
Query: 90 SRISNYRRQSSTVDSNSELSNEELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKILQ 149
++I + Q + S S L+ EEL + + E ++++ + L + + +L KEE LK +Q
Sbjct: 583 AQIQQFHSQIAAQTSASVLA-EELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQ 641
Query: 150 SMAILGKATSHTQAVLQKTMEQNRSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNC 209
+M L KA +++ ++L E A E+E +++S K D++
Sbjct: 642 NMNFLLKA----------EVQKLQALANEQAAAAHELE-------KMQQSVYVKDDKIRL 684
Query: 210 ENAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAMLDIKQQKMAQENM 258
L+ + K EE K+L N L + ++ + K E M
Sbjct: 685 LEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQM 733
Score = 35.4 bits (80), Expect = 0.12
Identities = 36/156 (23%), Positives = 76/156 (48%), Gaps = 8/156 (5%)
Query: 102 VDSNSELSNEELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKILQS-MAILGKATSH 160
+ S EL EL + N+ + ++++ Q L+GKEE + +++ + K ++
Sbjct: 810 IKSVEELLEAELLKVANKEKTVQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLAN 869
Query: 161 TQAVLQKTMEQNRSLE---KEINALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLKE- 216
T LQ E+N SL+ +E+ + ++F+ +E +K + L A+LKE
Sbjct: 870 TGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKER 929
Query: 217 --NLKVKTEEIKMLKSDNAVLNQRYLEALAMLDIKQ 250
+L KT+ ++ ++ +N + + +E L + +Q
Sbjct: 930 ESDLSSKTQLLQDVQDENKLFKSQ-IEQLKQQNYQQ 964
Score = 35.0 bits (79), Expect = 0.16
Identities = 64/327 (19%), Positives = 122/327 (37%), Gaps = 67/327 (20%)
Query: 103 DSNSELSNEELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQ 162
D+ + S EL +++ E+ ++L E + K+ ++ Q M +
Sbjct: 317 DALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAAT---KDRCKQLTQEMMT---EKERSN 370
Query: 163 AVLQKTMEQNRSLEKEINALQWEIEFDHN-------RFKNIEESWIQKYDRLNCENAVLK 215
V+ + ++ +LEKE N Q +I + +F+ + E + L EN +L+
Sbjct: 371 VVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILR 430
Query: 216 ENLKVKTEEIKMLKS-DNAVLNQRYLEALAMLDIKQQKMAQENMCCDKSGFAEASGLELA 274
+ + T +++ +S + L Q Y + L K K+ QE +
Sbjct: 431 DAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEV---------------- 474
Query: 275 VLGACLCHGPGGNPCSCARMAASTRKLLLQLKQELEILQKSKEEAYVMADAFRIAFEQQL 334
+ + QLK +L+ ++ EE Q
Sbjct: 475 -------------------QKKNAEQAATQLKVQLQEAERRWEEV------------QSY 503
Query: 335 MRKNDQALQLTQMDKMHKKATKWMNWKHLKEDGFPSPRSKKTFGQRLLGMLPSENSSKRM 394
+RK + Q D K K + L + SK+ QRL+ ++ SE KR+
Sbjct: 504 IRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESE--QKRV 561
Query: 395 EDQDSPQEVLKMLIDLLNDKEEALAHQ 421
++S L+M + + ++ EAL Q
Sbjct: 562 NKEES----LQMQVQDILEQNEALKAQ 584
Score = 31.2 bits (69), Expect = 2.3
Identities = 66/316 (20%), Positives = 124/316 (39%), Gaps = 45/316 (14%)
Query: 111 EELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQAVLQKTME 170
E++ +C+ E E+++ ++ LE Q+ KEE L AI + +S T+ V +
Sbjct: 731 EQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELN-----AIRTENSSLTKEVQDLKAK 785
Query: 171 QNR--SLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLKENLKVKTEEIK-M 227
QN S + L+ I + K++EE + ++ + ++ ++ K +E++ +
Sbjct: 786 QNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQLSITSKVQELQNL 845
Query: 228 LKSDNAVLNQRYLEALAMLDIKQQKMAQENMCCDKSGFAEASGLELAVLGACLCHGPGGN 287
LK +N A+L+ K++ +A E + A + H
Sbjct: 846 LKGKEEQMN----TMKAVLEEKEKDLANTGKWL--QDLQEENESLKAHVQEVAQHN---- 895
Query: 288 PCSCARMAASTRKLLLQLKQELEILQKSKEEAYVMADAFRIAFEQQLMRKNDQALQLTQM 347
+ A+S + +ELEI+ K KE +A E L K +
Sbjct: 896 ----LKEASSASQF-----EELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDE 946
Query: 348 DKMHKKATKWMNWKHLKEDGFPSPRSKKTFGQRLLGMLPSENSSKRMEDQDSPQEVLKML 407
+K+ K + LK+ + Q+ P E K + +++ L
Sbjct: 947 NKLFKSQI-----EQLKQQNY----------QQASSFPPHEELLKVISEREKEISGLWNE 991
Query: 408 IDLLNDKEEALAHQRK 423
+D L D A+ HQRK
Sbjct: 992 LDSLKD---AVEHQRK 1004
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 43.5 bits (101), Expect = 5e-04
Identities = 40/169 (23%), Positives = 75/169 (44%), Gaps = 18/169 (10%)
Query: 90 SRISNYRRQSSTVDSNSELSNEELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKILQ 149
++I + Q + S S L+ EEL + + E ++++ + L + + +L KEE LK +Q
Sbjct: 583 AQIQQFHSQIAAQTSASVLA-EELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQ 641
Query: 150 SMAILGKATSHTQAVLQKTMEQNRSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNC 209
+M L KA +++ ++L E A E+E +++S K D++
Sbjct: 642 NMNFLLKA----------EVQKLQALANEQAAAAHELE-------KMQQSVYVKDDKIRL 684
Query: 210 ENAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAMLDIKQQKMAQENM 258
L+ + K EE K+L N L + ++ + K E M
Sbjct: 685 LEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQM 733
Score = 38.1 bits (87), Expect = 0.019
Identities = 74/326 (22%), Positives = 127/326 (38%), Gaps = 42/326 (12%)
Query: 111 EELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQAVLQKTME 170
E++ +C+ E E+++ ++ LE Q+ KEE L AI + +S T+ V +
Sbjct: 731 EQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELN-----AIRTENSSLTKEVQDLKAK 785
Query: 171 QNR--SLEKEINALQWEIEFDHNRFKNIEESWIQKYDRL-NCENAV--LKENLKVKTEEI 225
QN S + L+ I + K++EE + ++ N E V LK+ +K EEI
Sbjct: 786 QNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEI 845
Query: 226 ---KMLKSDNAVLNQRYLEALAMLDIKQQKMAQENMCCDKSGFAEASGLELAVLGACLCH 282
++ K+ + + E +L K+++M E +LA G L
Sbjct: 846 GNVQLEKAQQLSITSKVQELQNLLKGKEEQMN------TMKAVLEEKEKDLANTGKWLQD 899
Query: 283 GPGGNPCSCARMAASTRKLLLQLK-----QELEILQKSKEEAYVMADAFRIAFEQQLMRK 337
N A + + L + +ELEI+ K KE +A E L K
Sbjct: 900 LQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSK 959
Query: 338 NDQALQLTQMDKMHKKATKWMNWKHLKEDGFPSPRSKKTFGQRLLGMLPSENSSKRMEDQ 397
+ +K+ K + LK+ + Q+ P E K + ++
Sbjct: 960 TQLLQDVQDENKLFKSQI-----EQLKQQNY----------QQASSFPPHEELLKVISER 1004
Query: 398 DSPQEVLKMLIDLLNDKEEALAHQRK 423
+ L +D L D A+ HQRK
Sbjct: 1005 EKEISGLWNELDSLKD---AVEHQRK 1027
Score = 35.0 bits (79), Expect = 0.16
Identities = 64/327 (19%), Positives = 122/327 (37%), Gaps = 67/327 (20%)
Query: 103 DSNSELSNEELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQ 162
D+ + S EL +++ E+ ++L E + K+ ++ Q M +
Sbjct: 317 DALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAAT---KDRCKQLTQEMMT---EKERSN 370
Query: 163 AVLQKTMEQNRSLEKEINALQWEIEFDHN-------RFKNIEESWIQKYDRLNCENAVLK 215
V+ + ++ +LEKE N Q +I + +F+ + E + L EN +L+
Sbjct: 371 VVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILR 430
Query: 216 ENLKVKTEEIKMLKS-DNAVLNQRYLEALAMLDIKQQKMAQENMCCDKSGFAEASGLELA 274
+ + T +++ +S + L Q Y + L K K+ QE +
Sbjct: 431 DAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEV---------------- 474
Query: 275 VLGACLCHGPGGNPCSCARMAASTRKLLLQLKQELEILQKSKEEAYVMADAFRIAFEQQL 334
+ + QLK +L+ ++ EE Q
Sbjct: 475 -------------------QKKNAEQAATQLKVQLQEAERRWEEV------------QSY 503
Query: 335 MRKNDQALQLTQMDKMHKKATKWMNWKHLKEDGFPSPRSKKTFGQRLLGMLPSENSSKRM 394
+RK + Q D K K + L + SK+ QRL+ ++ SE KR+
Sbjct: 504 IRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESE--QKRV 561
Query: 395 EDQDSPQEVLKMLIDLLNDKEEALAHQ 421
++S L+M + + ++ EAL Q
Sbjct: 562 NKEES----LQMQVQDILEQNEALKAQ 584
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 43.5 bits (101), Expect = 5e-04
Identities = 40/169 (23%), Positives = 75/169 (44%), Gaps = 18/169 (10%)
Query: 90 SRISNYRRQSSTVDSNSELSNEELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKILQ 149
++I + Q + S S L+ EEL + + E ++++ + L + + +L KEE LK +Q
Sbjct: 583 AQIQQFHSQIAAQTSASVLA-EELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQ 641
Query: 150 SMAILGKATSHTQAVLQKTMEQNRSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNC 209
+M L KA +++ ++L E A E+E +++S K D++
Sbjct: 642 NMNFLLKA----------EVQKLQALANEQAAAAHELE-------KMQQSVYVKDDKIRL 684
Query: 210 ENAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAMLDIKQQKMAQENM 258
L+ + K EE K+L N L + ++ + K E M
Sbjct: 685 LEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQM 733
Score = 40.0 bits (92), Expect = 0.005
Identities = 80/358 (22%), Positives = 140/358 (39%), Gaps = 42/358 (11%)
Query: 111 EELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQAVLQKTME 170
E++ +C+ E E+++ ++ LE Q+ KEE L AI + +S T+ V +
Sbjct: 731 EQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELN-----AIRTENSSLTKEVQDLKAK 785
Query: 171 QNR--SLEKEINALQWEIEFDHNRFKNIEESWIQKYDRL-NCENAV--LKENLKVKTEEI 225
QN S + L+ I + K++EE + ++ N E V LK+ +K EEI
Sbjct: 786 QNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEI 845
Query: 226 ---KMLKSDNAVLNQRYLEALAMLDIKQQKMAQENMCCDKSGFAEASGLELAVLGACLCH 282
++ K+ + + E +L K+++M E +LA G L
Sbjct: 846 GNVQLEKAQQLSITSKVQELQNLLKGKEEQMN------TMKAVLEEKEKDLANTGKWLQD 899
Query: 283 GPGGNPCSCARMAASTRKLLLQLK-----QELEILQKSKEEAYVMADAFRIAFEQQLMRK 337
N A + + L + +ELEI+ K KE +A E L K
Sbjct: 900 LQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSK 959
Query: 338 NDQALQLTQMDKMHKKATKWMNWKHLKEDGFPSPRSKKTFGQRLLGMLPSENSSKRMEDQ 397
+ +K+ K + LK+ + Q+ P E K + ++
Sbjct: 960 TQLLQDVQDENKLFKSQI-----EQLKQQNY----------QQASSFPPHEELLKVISER 1004
Query: 398 DSPQEVLKMLIDLLNDKEEALAHQRKVSYMLARALEDKDTASNENKEKNPIKENFPFN 455
+ L +D L D A+ HQRK + + +E + + E +K K + P N
Sbjct: 1005 EKEISGLWNELDSLKD---AVEHQRKKNNERQQQVEAVELEAKEVLKKLFPKVSVPSN 1059
Score = 35.0 bits (79), Expect = 0.16
Identities = 64/327 (19%), Positives = 122/327 (37%), Gaps = 67/327 (20%)
Query: 103 DSNSELSNEELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQ 162
D+ + S EL +++ E+ ++L E + K+ ++ Q M +
Sbjct: 317 DALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAAT---KDRCKQLTQEMMT---EKERSN 370
Query: 163 AVLQKTMEQNRSLEKEINALQWEIEFDHN-------RFKNIEESWIQKYDRLNCENAVLK 215
V+ + ++ +LEKE N Q +I + +F+ + E + L EN +L+
Sbjct: 371 VVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILR 430
Query: 216 ENLKVKTEEIKMLKS-DNAVLNQRYLEALAMLDIKQQKMAQENMCCDKSGFAEASGLELA 274
+ + T +++ +S + L Q Y + L K K+ QE +
Sbjct: 431 DAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEV---------------- 474
Query: 275 VLGACLCHGPGGNPCSCARMAASTRKLLLQLKQELEILQKSKEEAYVMADAFRIAFEQQL 334
+ + QLK +L+ ++ EE Q
Sbjct: 475 -------------------QKKNAEQAATQLKVQLQEAERRWEEV------------QSY 503
Query: 335 MRKNDQALQLTQMDKMHKKATKWMNWKHLKEDGFPSPRSKKTFGQRLLGMLPSENSSKRM 394
+RK + Q D K K + L + SK+ QRL+ ++ SE KR+
Sbjct: 504 IRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESE--QKRV 561
Query: 395 EDQDSPQEVLKMLIDLLNDKEEALAHQ 421
++S L+M + + ++ EAL Q
Sbjct: 562 NKEES----LQMQVQDILEQNEALKAQ 584
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 43.5 bits (101), Expect = 5e-04
Identities = 40/169 (23%), Positives = 75/169 (44%), Gaps = 18/169 (10%)
Query: 90 SRISNYRRQSSTVDSNSELSNEELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKILQ 149
++I + Q + S S L+ EEL + + E ++++ + L + + +L KEE LK +Q
Sbjct: 583 AQIQQFHSQIAAQTSASVLA-EELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQ 641
Query: 150 SMAILGKATSHTQAVLQKTMEQNRSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNC 209
+M L KA +++ ++L E A E+E +++S K D++
Sbjct: 642 NMNFLLKA----------EVQKLQALANEQAAAAHELE-------KMQQSVYVKDDKIRL 684
Query: 210 ENAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAMLDIKQQKMAQENM 258
L+ + K EE K+L N L + ++ + K E M
Sbjct: 685 LEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQM 733
Score = 38.1 bits (87), Expect = 0.019
Identities = 74/326 (22%), Positives = 127/326 (38%), Gaps = 42/326 (12%)
Query: 111 EELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQAVLQKTME 170
E++ +C+ E E+++ ++ LE Q+ KEE L AI + +S T+ V +
Sbjct: 731 EQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELN-----AIRTENSSLTKEVQDLKAK 785
Query: 171 QNR--SLEKEINALQWEIEFDHNRFKNIEESWIQKYDRL-NCENAV--LKENLKVKTEEI 225
QN S + L+ I + K++EE + ++ N E V LK+ +K EEI
Sbjct: 786 QNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEI 845
Query: 226 ---KMLKSDNAVLNQRYLEALAMLDIKQQKMAQENMCCDKSGFAEASGLELAVLGACLCH 282
++ K+ + + E +L K+++M E +LA G L
Sbjct: 846 GNVQLEKAQQLSITSKVQELQNLLKGKEEQMN------TMKAVLEEKEKDLANTGKWLQD 899
Query: 283 GPGGNPCSCARMAASTRKLLLQLK-----QELEILQKSKEEAYVMADAFRIAFEQQLMRK 337
N A + + L + +ELEI+ K KE +A E L K
Sbjct: 900 LQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSK 959
Query: 338 NDQALQLTQMDKMHKKATKWMNWKHLKEDGFPSPRSKKTFGQRLLGMLPSENSSKRMEDQ 397
+ +K+ K + LK+ + Q+ P E K + ++
Sbjct: 960 TQLLQDVQDENKLFKSQI-----EQLKQQNY----------QQASSFPPHEELLKVISER 1004
Query: 398 DSPQEVLKMLIDLLNDKEEALAHQRK 423
+ L +D L D A+ HQRK
Sbjct: 1005 EKEISGLWNELDSLKD---AVEHQRK 1027
Score = 35.0 bits (79), Expect = 0.16
Identities = 64/327 (19%), Positives = 122/327 (37%), Gaps = 67/327 (20%)
Query: 103 DSNSELSNEELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQ 162
D+ + S EL +++ E+ ++L E + K+ ++ Q M +
Sbjct: 317 DALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAAT---KDRCKQLTQEMMT---EKERSN 370
Query: 163 AVLQKTMEQNRSLEKEINALQWEIEFDHN-------RFKNIEESWIQKYDRLNCENAVLK 215
V+ + ++ +LEKE N Q +I + +F+ + E + L EN +L+
Sbjct: 371 VVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILR 430
Query: 216 ENLKVKTEEIKMLKS-DNAVLNQRYLEALAMLDIKQQKMAQENMCCDKSGFAEASGLELA 274
+ + T +++ +S + L Q Y + L K K+ QE +
Sbjct: 431 DAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEV---------------- 474
Query: 275 VLGACLCHGPGGNPCSCARMAASTRKLLLQLKQELEILQKSKEEAYVMADAFRIAFEQQL 334
+ + QLK +L+ ++ EE Q
Sbjct: 475 -------------------QKKNAEQAATQLKVQLQEAERRWEEV------------QSY 503
Query: 335 MRKNDQALQLTQMDKMHKKATKWMNWKHLKEDGFPSPRSKKTFGQRLLGMLPSENSSKRM 394
+RK + Q D K K + L + SK+ QRL+ ++ SE KR+
Sbjct: 504 IRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESE--QKRV 561
Query: 395 EDQDSPQEVLKMLIDLLNDKEEALAHQ 421
++S L+M + + ++ EAL Q
Sbjct: 562 NKEES----LQMQVQDILEQNEALKAQ 584
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 43.5 bits (101), Expect = 5e-04
Identities = 39/190 (20%), Positives = 90/190 (47%), Gaps = 11/190 (5%)
Query: 68 ERNEASFQYSKHKSQQDTFPQVSRISNYRRQSSTVDSNSELSNEELRQCLNETLEEVEML 127
E+ + S + ++ Q+TF Q+ Y R+S + + +L + E E++ +
Sbjct: 1010 EKEKISVLQNNYEKSQETFKQLQS-DFYGRESELLATRQDLKSVE---------EKLSLA 1059
Query: 128 KTELEASQRQLRGKEEALKILQSM-AILGKATSHTQAVLQKTMEQNRSLEKEINALQWEI 186
+ +L +++ Q+ + + ++ L++ A L + ++ + LQ+ + + ++KE + + E+
Sbjct: 1060 QEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKEL 1119
Query: 187 EFDHNRFKNIEESWIQKYDRLNCENAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAML 246
+ ++ IEE ++ + N LK + +EI LK +L Q+ LE
Sbjct: 1120 VNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKA 1179
Query: 247 DIKQQKMAQE 256
D + + QE
Sbjct: 1180 DSLKAAVEQE 1189
Score = 42.0 bits (97), Expect = 0.001
Identities = 83/391 (21%), Positives = 160/391 (40%), Gaps = 65/391 (16%)
Query: 65 KGEERNEASFQYSKHKSQQDTFPQVSRISNYRRQSSTVDSNSELSNEELRQCLNETLEEV 124
K ++ + S + K S Q S + +T+ N E ++L+ +NE +
Sbjct: 910 KEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQN-EKEEQQLQGNINELKQSS 968
Query: 125 EMLKTELEASQRQL------------RGKEEALKILQSMAILGKATSHTQAVLQKTMEQN 172
E K ++EA Q +L + +++ + Q +A + S Q +K+ E
Sbjct: 969 EQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETF 1028
Query: 173 RSLEKEINALQWEIEFDHNRFKNIEESW-IQKYDRLNCENAVLKENLKVKTEEIK----M 227
+ L+ + + E+ K++EE + + D ++ N + +N + +E+K
Sbjct: 1029 KQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLI--QELKTAKAT 1086
Query: 228 LKSDNAVLNQRYLE-ALAMLDIKQQK-MAQENMCCDKSGFAEASGL------ELAVLGAC 279
L+ D+A Q+ E A+ DI+++K + ++ + +KS AE + E+ L
Sbjct: 1087 LEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEE 1146
Query: 280 LCHGPGGNPCSCARMAASTRKLLLQLKQELEILQKSKEEAYVMADAFRIAFEQQLMRKND 339
L + K + LK ++L + K E AD+ + A EQ+ ++N
Sbjct: 1147 L-----------KSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQE--KRNQ 1193
Query: 340 QALQLTQMDKMHKKATKWMNWKHLKEDGFPSPRSKKTFGQRLLGMLPSENSSKRMEDQDS 399
Q L+ D++ K+ + KE S +K G M+ +
Sbjct: 1194 QILK----DQVKKEEEELKKEFIEKEAKLHSEIKEKEVG---------------MKKHEE 1234
Query: 400 PQEVLKMLIDLLND-----KEEALAHQRKVS 425
+ L M I LN+ K+E + QR+VS
Sbjct: 1235 NEAKLTMQITALNENLGTVKKEWQSSQRRVS 1265
Score = 37.4 bits (85), Expect = 0.033
Identities = 82/393 (20%), Positives = 151/393 (38%), Gaps = 55/393 (13%)
Query: 67 EERNEASFQYSKHKSQQDTFPQVSRISNYRRQSSTVDSNSELSNE-ELRQCLNETLEEVE 125
E ++ + Q + H+ D SR+S ++S + ELS + E Q L E L EVE
Sbjct: 328 ESVSKKNIQATLHQKDLDCQQLQSRLS--ASETSLHRIHVELSEKGEATQKLKEELSEVE 385
Query: 126 MLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQAVLQKTMEQNRSLEKEINALQWE 185
L+A +QL+ + E + + L+ EIN L
Sbjct: 386 TKYQHLKAEFKQLQQQRE-----------------------EKEQHGLQLQSEINQL--- 419
Query: 186 IEFDHNRFKNIEESWIQKYDRLNCENAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALA- 244
H++ E + + RL + + E L K +++ L+ + L ++ E +
Sbjct: 420 ----HSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTN 475
Query: 245 ------MLDIKQQKMAQENMCCDKSGFAEASGLELAVLGACLCHGPGGNPCSCARMAAST 298
LD K ++ QE +S A+ + + G + +
Sbjct: 476 STELQHQLD-KTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKD------QKIQNL 528
Query: 299 RKLLLQLKQELEILQKSKEEAY--VMADAFRIAFEQQLMRKN----DQALQLTQMDKMHK 352
LL + K+ + +L+K +E+ Y + A A QL KN +Q QLT+ K
Sbjct: 529 EALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQS 588
Query: 353 KATKWMNWKHLKEDGFPSPRSKKTFGQRLLGMLPSENSSKRMEDQDSPQEVLKMLIDLLN 412
++ K ++L + + R+L + S N + +S ++V ++ I +
Sbjct: 589 ESHKQAQ-ENLHDQVQEQKAHLRAAQDRVLSLETSVN-ELNSQLNESKEKVSQLDIQIKA 646
Query: 413 DKEEALAHQRKVSYMLARALEDKDTASNENKEK 445
E L+ + + A DTA N ++K
Sbjct: 647 KTELLLSAEAAKTAQRADLQNHLDTAQNALQDK 679
Score = 35.4 bits (80), Expect = 0.12
Identities = 77/399 (19%), Positives = 159/399 (39%), Gaps = 60/399 (15%)
Query: 82 QQDTFPQVSRISNYRRQSSTVDSNSELSNEELRQC--LNETLE--------EVEMLKTEL 131
+Q T +I S V ++ E + ++L+Q LN LE ++EM K +
Sbjct: 722 EQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIV 781
Query: 132 EASQRQLRGKEEALKILQSMAILGKATSHTQAVLQKTMEQNRSLEKEINALQWEIEFDHN 191
+++ L+ K EAL+ ++ L K E+ + L+++ L E + H
Sbjct: 782 SSTRLDLQKKSEALESIKQK-------------LTKQEEEKQILKQDFETLSQETKIQHE 828
Query: 192 RFKNIEESWIQKYDRLNCENAVL-------KENLKVKTEEIKMLKSDNAVLNQRYLEALA 244
N ++ + + ++ E L K+ L ++ +K KS+ NQ+ A+
Sbjct: 829 ELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAIL 888
Query: 245 MLD-----------------IKQQKMAQENMCCDKSGFAEASGLELAVLGACLCHGPGGN 287
L+ +K+QK ++++ +K + LEL + L
Sbjct: 889 DLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLK-LELNSMQEQLIQAQN-- 945
Query: 288 PCSCARMAASTRKLLLQLKQELEILQKSKEEAYVMADAFRIAFEQQLMRKNDQALQLTQM 347
+ + ++L + + + ++ K++ + +IA Q+ +N QLTQ
Sbjct: 946 --TLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQ- 1002
Query: 348 DKMHKKATKWMNWKHLKEDGFPSPRSKKTFGQRLLGMLPSENS-SKRMEDQDSPQEVLKM 406
+ A + L+ + +S++TF Q E+ +D S +E L +
Sbjct: 1003 -AAQELAAEKEKISVLQNN---YEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSL 1058
Query: 407 LIDLLNDKEEALAHQRKVSYML--ARALEDKDTASNENK 443
+ L + +Q K+ L A+A ++D+A E +
Sbjct: 1059 AQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQ 1097
Score = 35.0 bits (79), Expect = 0.16
Identities = 42/213 (19%), Positives = 95/213 (44%), Gaps = 21/213 (9%)
Query: 65 KGEERNEASFQYSKHKSQQDTFPQVSRISNYRRQSSTVDSNSELSN--EELRQCLNETLE 122
K + N Q+ K++Q Q + Q ST E N E++ + + + +
Sbjct: 470 KEKVTNSTELQHQLDKTKQQHQEQQAL------QQSTTAKLREAQNDLEQVLRQIGDKDQ 523
Query: 123 EVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQAVLQKTMEQNRSLEKEINAL 182
+++ L+ L+ S+ + E+ + L + G+ + AVL + E+N +L++++ L
Sbjct: 524 KIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGET---AVLNQLQEKNHTLQEQVTQL 580
Query: 183 QWEIEFDHNRFKNIEESWIQKYDRLNCENAVLKENLKVKTEEIKMLKSDNAVLNQRYLEA 242
+ KN ES Q + L+ + K +L+ + + L++ LN + E+
Sbjct: 581 T-------EKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNES 633
Query: 243 ---LAMLDIKQQKMAQENMCCDKSGFAEASGLE 272
++ LDI+ + + + + + A+ + L+
Sbjct: 634 KEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQ 666
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 43.1 bits (100), Expect = 6e-04
Identities = 85/380 (22%), Positives = 155/380 (40%), Gaps = 47/380 (12%)
Query: 123 EVEMLKTELEASQRQLRGK-EEALKILQ----SMAILGKATSHTQAVLQKTMEQNRSLEK 177
E+E +L+ + +QLR EEA K +LG+ + + L++T E+N +
Sbjct: 678 ELEEQNLQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRR 737
Query: 178 EINALQWEIEFDHNRF---KNIEESWIQKYDRLNCENAVLKENLKVKTEEIKMLKSDNAV 234
I L+ +++ + +E K RL E L+E L EE L +
Sbjct: 738 RILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRA 797
Query: 235 LNQRYLEA---LAMLDIKQQKMAQENMCCDKSG----FAEASGLELAVLGACLCHGPGGN 287
L R EA LA L +QQ + N ++ G EL L
Sbjct: 798 LEARLEEAQRGLARLGQEQQTL---NRALEEEGKQREVLRRGKAELEEQKRLLDRTVDRL 854
Query: 288 PCSCARMAASTRKLLLQLKQELE-ILQKSKEEAYVMADAFRIAFE--------------- 331
++ +++ L QL+ +LE +K++ E +ADA R A +
Sbjct: 855 NKELEKIGEDSKQALQQLQAQLEDYKEKARRE---VADAQRQAKDWASEAEKTSGGLSRL 911
Query: 332 QQLMRKNDQALQLTQMDKMHKKATKWM---NWKHLKEDGFPSPRSKKTFGQRLLGMLPSE 388
Q +++ QALQ +Q ++ + K + + L+++ RS+ ++L G+ E
Sbjct: 912 QDEIQRLRQALQASQAERDTARLDKELLAQRLQGLEQEAENKKRSQDDRARQLKGL--EE 969
Query: 389 NSSKRMEDQDSPQEVLKMLIDLLN---DKEEALAHQRKVSYMLARALE-DKDTASNENKE 444
S+ + D + +++L D +N D+ + L + + LE DK + +NK+
Sbjct: 970 KVSRLETELDEEKNTVELLTDRVNRGRDQVDQLRTELMQERSARQDLECDKISLERQNKD 1029
Query: 445 -KNPIKENFPFNNPWRKTSE 463
K + + F P S+
Sbjct: 1030 LKTRLASSEGFQKPSASLSQ 1049
Score = 31.6 bits (70), Expect = 1.8
Identities = 54/307 (17%), Positives = 120/307 (39%), Gaps = 31/307 (10%)
Query: 112 ELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQAVLQKTMEQ 171
E R+ L E LE + ++ +L +R+L + ALK + +A + H + Q+ EQ
Sbjct: 471 ETRELLEEVLEGKQRVEEQLRLRERELTALKGALK--EEVASRDQEVEHVRQQYQRDTEQ 528
Query: 172 NRSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLKENLKVKTEEIKMLKSD 231
R ++ +E + + + ++ + + E + + E+++ K +
Sbjct: 529 LRRSMQDATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQE 588
Query: 232 NAVLNQRYLEALAMLDIKQQKMAQENMCCDKSGFAEASGLELAVLGACLCHGPGGNPCSC 291
+L ++ +K E +K + LE A A
Sbjct: 589 -------------LLQLRMEKEEMEEELGEKIEVLQRE-LEQARASA-----------GD 623
Query: 292 ARMAASTRKLLLQLKQELEILQKSKEEAYVMADAFRIAFEQQLMRKNDQALQLTQMDKMH 351
R +K LL+ ++EL+ LQ ++ V E+QL +A + ++++ +
Sbjct: 624 TRQVEVLKKELLRTQEELKELQAERQSQEVAGRHRDRELEKQLAVLRVEADRGRELEEQN 683
Query: 352 KKATKWMNWKHLKEDGFPSPRSKKTFGQR--LLGMLPSENSSKRMEDQDSPQEVLKMLID 409
+ K + + L++D + ++K +LG + + E Q+ E + ++
Sbjct: 684 LQLQKTL--QQLRQDCEEASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRRRILG 741
Query: 410 LLNDKEE 416
L +E
Sbjct: 742 LEQQLKE 748
Score = 30.0 bits (66), Expect = 5.2
Identities = 75/349 (21%), Positives = 137/349 (39%), Gaps = 44/349 (12%)
Query: 109 SNEELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQAVLQKT 168
+ +EL Q E E E L ++E QR+L + + + +L K TQ L++
Sbjct: 585 TKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEVLKKELLRTQEELKEL 644
Query: 169 M-----------EQNRSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLKEN 217
++R LEK++ L+ E + R + +EE +Q L L+++
Sbjct: 645 QAERQSQEVAGRHRDRELEKQLAVLRVEAD----RGRELEEQNLQLQKTLQ----QLRQD 696
Query: 218 LKVKTEEIKMLKSDNAVLNQRYLEALAMLDIKQQKMAQ--ENMCCDKSGFAEASGLELAV 275
+ ++ + +++ VL QR L Q++ + + + E GL
Sbjct: 697 CEEASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRRRILGLEQQLKETRGL---- 752
Query: 276 LGACLCHGPGGNPCSCARMAASTRKLLLQLKQELEILQKSKEEAYVMADAFRIAFEQQLM 335
G AR+ ++L + +Q E L S+EE +A A R A E +L
Sbjct: 753 --------VDGGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKR-ALEARLE 803
Query: 336 RKNDQALQLTQ-MDKMHKKATKWMNWKHLKEDGFPSPRSKKTFGQRLLGMLPSENSSKRM 394
+L Q +++ + + + G +K R + L N
Sbjct: 804 EAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVDRL---NKELEK 860
Query: 395 EDQDSPQEVLKMLIDLLNDKEEALAHQRKVSYMLARALEDKDTASNENK 443
+DS Q + ++ L + KE+A +R+V+ +A KD AS K
Sbjct: 861 IGEDSKQALQQLQAQLEDYKEKA---RREVADAQRQA---KDWASEAEK 903
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 42.7 bits (99), Expect = 8e-04
Identities = 49/213 (23%), Positives = 96/213 (45%), Gaps = 25/213 (11%)
Query: 69 RNEASFQYSKHKSQQDTFPQVSRISNYRRQSSTVDSNSELSNEELRQCLNETLEEVEMLK 128
R E + Q K + ++D + RRQ + ++E+ +E R+ + + L+
Sbjct: 1589 RLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLE 1648
Query: 129 TELEASQRQL----RGKEEALKILQSMAI----LGKATSHTQAVLQKTMEQNRSLEK--- 177
ELE + Q+ +GKEEA+K L+ M L + T+ ++ QNR EK
Sbjct: 1649 GELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLK 1708
Query: 178 ----EINALQWEIEFDHNRFKNIEESWIQKYDRLNCEN----AVLKENLKVK------TE 223
E+ LQ E+ + ++ + D + N A+L+E +++ E
Sbjct: 1709 GLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEE 1768
Query: 224 EIKMLKSDNAVLNQRYLEALAMLDIKQQKMAQE 256
E++ +S++ +LN RY + L ++ +++ E
Sbjct: 1769 ELEEEQSNSELLNDRYRKLLLQVESLTTELSAE 1801
Score = 34.3 bits (77), Expect = 0.28
Identities = 75/367 (20%), Positives = 133/367 (36%), Gaps = 30/367 (8%)
Query: 64 RKGEERNEASFQYSKHKSQQDTFPQVSRISNYRRQSSTVDSNSELSNEELR-QCLNETLE 122
R G+ + K + Q VS N +S T+ + ELS+ E + E L+
Sbjct: 1292 RAGDGERARAEAAEKLQRAQAELENVSGALN-EAESKTIRLSKELSSTEAQLHDAQELLQ 1350
Query: 123 EVEMLKTELEASQRQLRGKEEALK--ILQSMAILGKATSHTQAVLQKTMEQNRSLEKEIN 180
E K L + R + + L+ + + A +A Q + E R E+E
Sbjct: 1351 EETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAG 1410
Query: 181 ALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLKENLKVKTEEIKMLKSDNAVLNQRYL 240
AL E+ + R E L + L KTE + L+ L Q
Sbjct: 1411 AL---------------EAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELD 1455
Query: 241 EALAMLDIKQQKMAQENMCCDKSGFAEASGLELAVLGACLCHGPGGNPCSCARMAASTRK 300
+A +D++QQ+ + + F + E A + + R A +
Sbjct: 1456 DAT--MDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA--- 1510
Query: 301 LLLQLKQELEILQKSKEEAYVMADAFRIAFEQQLMRKNDQALQLTQMDKMHKKATKWMNW 360
L L + LE Q+++EE A R E L K+D + ++++ + A + N
Sbjct: 1511 --LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAAND 1568
Query: 361 KHLK----EDGFPSPRSKKTFGQRLLGMLPSENSSKRMEDQDSPQEVLKMLIDLLNDKEE 416
+ ED + K + + L +++ ++ +E + L L D E
Sbjct: 1569 LRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEV 1628
Query: 417 ALAHQRK 423
+RK
Sbjct: 1629 ERDEERK 1635
Score = 29.6 bits (65), Expect = 6.8
Identities = 38/152 (25%), Positives = 72/152 (47%), Gaps = 22/152 (14%)
Query: 110 NEELRQCLNETLEEVEMLKTELEASQRQL-----RGKEEA---LKILQSMAILGKATSHT 161
+ EL++ + E + E L+ +L + +L R ++E ++L+S+ A +
Sbjct: 1089 SSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEA 1148
Query: 162 QAVLQ-------KTMEQNRSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVL 214
Q L+ K +Q R L +E+ AL+ E+E D N ++ K ++ E L
Sbjct: 1149 QEDLESERVARTKAEKQRRDLGEELEALRGELE-DTLDSTNAQQELRSKREQ---EVTEL 1204
Query: 215 KENLKVKTEEIKMLKSDNAVLNQRYLEALAML 246
K+ L+ EE ++ ++ L QR+ +AL L
Sbjct: 1205 KKTLE---EETRIHEAAVQELRQRHGQALGEL 1233
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.128 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,210,469
Number of Sequences: 37866
Number of extensions: 869303
Number of successful extensions: 4378
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 408
Number of HSP's that attempted gapping in prelim test: 3561
Number of HSP's gapped (non-prelim): 1146
length of query: 511
length of database: 18,247,518
effective HSP length: 107
effective length of query: 404
effective length of database: 14,195,856
effective search space: 5735125824
effective search space used: 5735125824
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.