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Search of human proteins with 8394291
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|8394291 solute carrier organic anion transporter family,
member 1C1 isoform 2 [Homo sapiens]
(712 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|8394291 solute carrier organic anion transporter family, memb... 1439 0.0
gi|225543116 solute carrier organic anion transporter family, me... 1316 0.0
gi|225543118 solute carrier organic anion transporter family, me... 1295 0.0
gi|225543114 solute carrier organic anion transporter family, me... 1061 0.0
gi|9790233 solute carrier organic anion transporter family, memb... 630 e-180
gi|225543525 solute carrier organic anion transporter family, me... 621 e-178
gi|10835099 organic anion transporting polypeptide A [Homo sapiens] 615 e-176
gi|19913403 organic anion transporting polypeptide A [Homo sapiens] 615 e-176
gi|116812593 liver-specific organic anion transporter 3TM12 [Hom... 563 e-160
gi|222831575 solute carrier organic anion transporter family, me... 415 e-116
gi|222831573 solute carrier organic anion transporter family, me... 414 e-115
gi|188528663 solute carrier organic anion transporter family, me... 384 e-106
gi|223634012 solute carrier organic anion transporter family, me... 352 5e-97
gi|6005820 solute carrier organic anion transporter family, memb... 352 5e-97
gi|38679890 solute carrier organic anion transporter family, mem... 325 1e-88
gi|225637473 solute carrier organic anion transporter family, me... 318 8e-87
gi|39777594 solute carrier organic anion transporter family memb... 311 1e-84
gi|225637475 solute carrier organic anion transporter family, me... 283 3e-76
gi|223634014 solute carrier organic anion transporter family, me... 270 3e-72
gi|225637477 solute carrier organic anion transporter family, me... 259 8e-69
gi|93277099 solute carrier organic anion transporter family, mem... 224 2e-58
gi|11863156 RECK protein precursor [Homo sapiens] 37 0.083
gi|42741679 ATPase, H+ transporting, lysosomal V0 subunit A2 [Ho... 32 1.6
gi|9945322 solute carrier family 17, member 7 [Homo sapiens] 32 2.0
gi|12383051 transmembrane protein with EGF-like and two follista... 31 4.5
gi|54873613 agrin [Homo sapiens] 30 5.9
gi|15451844 ADAM metallopeptidase domain 19 preproprotein [Homo ... 30 5.9
gi|156104876 fms-related tyrosine kinase 1 isoform 1 precursor [... 30 7.8
gi|229892220 fms-related tyrosine kinase 1 isoform 2 precursor [... 30 7.8
gi|229892302 fms-related tyrosine kinase 1 isoform 4 precursor [... 30 7.8
>gi|8394291 solute carrier organic anion transporter family, member
1C1 isoform 2 [Homo sapiens]
Length = 712
Score = 1439 bits (3724), Expect = 0.0
Identities = 712/712 (100%), Positives = 712/712 (100%)
Query: 1 MDTSSKENIQLFCKTSVQPVGRPSFKTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAE 60
MDTSSKENIQLFCKTSVQPVGRPSFKTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAE
Sbjct: 1 MDTSSKENIQLFCKTSVQPVGRPSFKTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAE 60
Query: 61 GYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMG 120
GYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMG
Sbjct: 61 GYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMG 120
Query: 121 VGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNECEV 180
VGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNECEV
Sbjct: 121 VGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNECEV 180
Query: 181 DTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGF 240
DTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGF
Sbjct: 181 DTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGF 240
Query: 241 LLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLP 300
LLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLP
Sbjct: 241 LLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLP 300
Query: 301 RSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLC 360
RSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLC
Sbjct: 301 RSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLC 360
Query: 361 TSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRIS 420
TSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRIS
Sbjct: 361 TSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRIS 420
Query: 421 VCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRC 480
VCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRC
Sbjct: 421 VCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRC 480
Query: 481 KCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGR 540
KCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGR
Sbjct: 481 KCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGR 540
Query: 541 CQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLA 600
CQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLA
Sbjct: 541 CQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLA 600
Query: 601 GIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAV 660
GIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAV
Sbjct: 601 GIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAV 660
Query: 661 LFILKKNYVSKHRSFITKRERTMVSTRFQKENYTTSDHLLQPNYWPGKETQL 712
LFILKKNYVSKHRSFITKRERTMVSTRFQKENYTTSDHLLQPNYWPGKETQL
Sbjct: 661 LFILKKNYVSKHRSFITKRERTMVSTRFQKENYTTSDHLLQPNYWPGKETQL 712
>gi|225543116 solute carrier organic anion transporter family,
member 1C1 isoform 3 [Homo sapiens]
Length = 663
Score = 1316 bits (3406), Expect = 0.0
Identities = 663/712 (93%), Positives = 663/712 (93%), Gaps = 49/712 (6%)
Query: 1 MDTSSKENIQLFCKTSVQPVGRPSFKTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAE 60
MDTSSKENIQLFCKTSVQPVGRPSFKTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAE
Sbjct: 1 MDTSSKENIQLFCKTSVQPVGRPSFKTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAE 60
Query: 61 GYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMG 120
GYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMG
Sbjct: 61 GYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMG 120
Query: 121 VGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNECEV 180
VGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISN
Sbjct: 121 VGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISN---- 176
Query: 181 DTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGF 240
GCVQTVAIIGPIFGF
Sbjct: 177 ---------------------------------------------GCVQTVAIIGPIFGF 191
Query: 241 LLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLP 300
LLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLP
Sbjct: 192 LLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLP 251
Query: 301 RSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLC 360
RSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLC
Sbjct: 252 RSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLC 311
Query: 361 TSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRIS 420
TSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRIS
Sbjct: 312 TSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRIS 371
Query: 421 VCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRC 480
VCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRC
Sbjct: 372 VCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRC 431
Query: 481 KCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGR 540
KCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGR
Sbjct: 432 KCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGR 491
Query: 541 CQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLA 600
CQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLA
Sbjct: 492 CQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLA 551
Query: 601 GIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAV 660
GIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAV
Sbjct: 552 GIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAV 611
Query: 661 LFILKKNYVSKHRSFITKRERTMVSTRFQKENYTTSDHLLQPNYWPGKETQL 712
LFILKKNYVSKHRSFITKRERTMVSTRFQKENYTTSDHLLQPNYWPGKETQL
Sbjct: 612 LFILKKNYVSKHRSFITKRERTMVSTRFQKENYTTSDHLLQPNYWPGKETQL 663
>gi|225543118 solute carrier organic anion transporter family,
member 1C1 isoform 1 [Homo sapiens]
Length = 730
Score = 1295 bits (3352), Expect = 0.0
Identities = 639/640 (99%), Positives = 640/640 (100%)
Query: 1 MDTSSKENIQLFCKTSVQPVGRPSFKTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAE 60
MDTSSKENIQLFCKTSVQPVGRPSFKTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAE
Sbjct: 1 MDTSSKENIQLFCKTSVQPVGRPSFKTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAE 60
Query: 61 GYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMG 120
GYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMG
Sbjct: 61 GYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMG 120
Query: 121 VGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNECEV 180
VGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNECEV
Sbjct: 121 VGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNECEV 180
Query: 181 DTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGF 240
DTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGF
Sbjct: 181 DTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGF 240
Query: 241 LLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLP 300
LLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLP
Sbjct: 241 LLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLP 300
Query: 301 RSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLC 360
RSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLC
Sbjct: 301 RSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLC 360
Query: 361 TSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRIS 420
TSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRIS
Sbjct: 361 TSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRIS 420
Query: 421 VCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRC 480
VCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRC
Sbjct: 421 VCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRC 480
Query: 481 KCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGR 540
KCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGR
Sbjct: 481 KCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGR 540
Query: 541 CQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLA 600
CQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLA
Sbjct: 541 CQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLA 600
Query: 601 GIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRH 640
GIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFR+
Sbjct: 601 GIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRY 640
>gi|225543114 solute carrier organic anion transporter family,
member 1C1 isoform 4 [Homo sapiens]
Length = 612
Score = 1061 bits (2743), Expect = 0.0
Identities = 521/522 (99%), Positives = 522/522 (100%)
Query: 119 MGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNEC 178
MGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNEC
Sbjct: 1 MGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNEC 60
Query: 179 EVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIF 238
EVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIF
Sbjct: 61 EVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIF 120
Query: 239 GFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKS 298
GFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKS
Sbjct: 121 GFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKS 180
Query: 299 LPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLY 358
LPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLY
Sbjct: 181 LPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLY 240
Query: 359 LCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFR 418
LCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFR
Sbjct: 241 LCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFR 300
Query: 419 ISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNS 478
ISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNS
Sbjct: 301 ISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNS 360
Query: 479 RCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIV 538
RCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIV
Sbjct: 361 RCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIV 420
Query: 539 GRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRV 598
GRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRV
Sbjct: 421 GRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRV 480
Query: 599 LAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRH 640
LAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFR+
Sbjct: 481 LAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRY 522
>gi|9790233 solute carrier organic anion transporter family, member
1B3 [Homo sapiens]
Length = 702
Score = 630 bits (1624), Expect = e-180
Identities = 308/652 (47%), Positives = 439/652 (67%), Gaps = 12/652 (1%)
Query: 26 KTEYPSSEEKQPC--CGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGV 83
KT +S EK+ C K+FL ALSF Y AKAL +K +ITQIERRFDI SSL G+
Sbjct: 9 KTAESASSEKKKTRRCNGFKMFLAALSFSYIAKALGGIIMKISITQIERRFDISSSLAGL 68
Query: 84 IDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYER--- 140
IDGSFEIGNLLVI FVSYFG+KLHRPK+IG GC++MG G++L ++P FFM Y+Y +
Sbjct: 69 IDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFMGYYRYSKETH 128
Query: 141 YSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNECEVDTSSSMWIYVFLGNLLRGIG 200
+PS NST S+S CL+ + +S S + +C ++ S MWIYVF+GN+LRGIG
Sbjct: 129 INPSENSTSSLSTCLINQT----LSFNGTSPEIVEKDCVKESGSHMWIYVFMGNMLRGIG 184
Query: 201 ETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDH 260
ETPI PLGI+Y+DDFA E +++ Y+G + + +IGP+ GF LGSL AK+YVDIG+V+L
Sbjct: 185 ETPIVPLGISYIDDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGYVDLST 244
Query: 261 ITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIID 320
I ITPKD +WVGAWWLG+L++G+ S+++++PF++LPK+ + Q + S K D
Sbjct: 245 IRITPKDSRWVGAWWLGFLVSGLFSIISSIPFFFLPKNPNKPQKERKISLSLHVLKTNDD 304
Query: 321 -DHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKY 379
+ T T QG+N + + F SLK++ NP+Y ++L + +Q +S G TY KY
Sbjct: 305 RNQTANLTNQGKN--VTKNVTGFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYVFKY 362
Query: 380 IEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLF 439
+EQQYGQS+S ANF++G+I IP VA G+F GG ++KKF++S+ G AK +S+ +L
Sbjct: 363 MEQQYGQSASHANFLLGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFLFQ 422
Query: 440 LSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYV 499
L F L CE+ VAGLT++Y G V+ H S CNS C C E++WEP+CG NGITY+
Sbjct: 423 LLYFPLICESKSVAGLTLTYDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGITYL 482
Query: 500 SACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISV 559
S CLAGC++S+ K+ +FYNC+CV + ++ N S +G C +DN C + F ++ I V
Sbjct: 483 SPCLAGCKSSSGIKKHTVFYNCSCVEVTGLQNRNYSAHLGECPRDNTCTRKFFIYVAIQV 542
Query: 560 ITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKW 619
I S + GG +L ++ ++P+LK+ A+G ++ IR L GI AP+YFG LID +C+KW
Sbjct: 543 INSLFSATGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKW 602
Query: 620 GFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKKNYVSK 671
CG++G+CR+Y+S F +YLGL++ L +++L I +F +KK + K
Sbjct: 603 STNSCGAQGACRIYNSVFFGRVYLGLSIALRFPALVLYIVFIFAMKKKFQGK 654
>gi|225543525 solute carrier organic anion transporter family,
member 1B1 [Homo sapiens]
Length = 691
Score = 621 bits (1602), Expect = e-178
Identities = 300/646 (46%), Positives = 433/646 (67%), Gaps = 10/646 (1%)
Query: 30 PSSEEKQPCCGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFE 89
PS +K C LK+FL ALS + AK L +KS+I IERRF+I SSLVG IDGSFE
Sbjct: 15 PSENKKTRYCNGLKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFEISSSLVGFIDGSFE 74
Query: 90 IGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYER---YSPSSN 146
IGNLLVI FVSYFG+KLHRPK+IG GC IMG+G +L A+P FFM Y+Y + + S N
Sbjct: 75 IGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGYYRYSKETNINSSEN 134
Query: 147 STLSISPCLLESSSQLPVSVMEKSKSKISNECEVDTSSSMWIYVFLGNLLRGIGETPIQP 206
ST ++S CL+ +S+ S + C ++ S MWIYVF+GN+LRGIGETPI P
Sbjct: 135 STSTLSTCLINQI----LSLNRASPEIVGKGCLKESGSYMWIYVFMGNMLRGIGETPIVP 190
Query: 207 LGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPK 266
LG++Y+DDFA E +++ Y+G + +A+IGPI GF LGSL +K+YVDIG+V+L I ITP
Sbjct: 191 LGLSYIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITPT 250
Query: 267 DPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIID-DHTDY 325
D +WVGAWWL +L++G+ S+++++PF++LP++ + Q ++ S + + D T
Sbjct: 251 DSRWVGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKASLSLHVLETNDEKDQTAN 310
Query: 326 QTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYG 385
T QG+N I + F S K++ NP+Y +++ + +Q +S G TY KY+EQQYG
Sbjct: 311 LTNQGKN--ITKNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYG 368
Query: 386 QSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFAL 445
Q SS+AN ++G+I IP A G+F GG ++KKF+++ G AK ++V +L F +
Sbjct: 369 QPSSKANILLGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFI 428
Query: 446 GCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAG 505
CEN VAGLT++Y G PV+ H S CNS C C E++WEP+CG NGITY+S CLAG
Sbjct: 429 LCENKSVAGLTMTYDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAG 488
Query: 506 CQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTL 565
C++S+ + K I+FYNC+C+ + ++ N S +G C +D+ C + F +F+ I V+ +
Sbjct: 489 CKSSSGNKKPIVFYNCSCLEVTGLQNRNYSAHLGECPRDDACTRKFYFFVAIQVLNLFFS 548
Query: 566 SLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCG 625
+LGG +L+++ ++P+LKS ALG +++ IR L GI AP+YFG LIDT+C+KW CG
Sbjct: 549 ALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWSTNNCG 608
Query: 626 SRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKKNYVSK 671
+RGSCR Y+S F +YLGL+ +L S++L I +++ +KK Y K
Sbjct: 609 TRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKKKYQEK 654
>gi|10835099 organic anion transporting polypeptide A [Homo sapiens]
Length = 670
Score = 615 bits (1586), Expect = e-176
Identities = 295/641 (46%), Positives = 426/641 (66%), Gaps = 18/641 (2%)
Query: 26 KTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVID 85
+TE + C +LK+FL A++ + +K L+ Y+ S +TQIER+F+IP+SLVG I+
Sbjct: 3 ETEKRIETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFIN 62
Query: 86 GSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSS 145
GSFEIGNLL+I FVSYFG KLHRP +IG GCV+MG+G L ++P F M QY+YE S
Sbjct: 63 GSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVS 122
Query: 146 NSTLSISPCLLESSSQLPVSVMEKSKSKISNECEVDTSSSMWIYVFLGNLLRGIGETPIQ 205
+ S S +E+ +Q+ + S EC + S MW+YV +GN++RG+GETPI
Sbjct: 123 GNLSSNSFLCMENGTQILRPTQDPS------ECTKEVKSLMWVYVLVGNIVRGMGETPIL 176
Query: 206 PLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITP 265
PLGI+Y++DFA +N+ YIG V+T AIIGP+ G LL S CA +YVD GFVN D + ITP
Sbjct: 177 PLGISYIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITP 236
Query: 266 KDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDY 325
D +WVGAWW G+LI +++L A+PF++LP +LP+ +++ I +++ D
Sbjct: 237 TDTRWVGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNAD-------IIKNENEDK 289
Query: 326 QTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYG 385
Q + + K + +DFLP +K+L NP+Y L++ S +QFN+ M+++ PKY+EQQYG
Sbjct: 290 QKEEVKKEKY-GITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYG 348
Query: 386 QSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFAL 445
SSS A F++G+ N+P + +G GG++MKKF+I+V AA + S+ YLL+ F +
Sbjct: 349 ISSSDAIFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLM 408
Query: 446 GCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAG 505
CENS V G+ SY+G Y E +F+DCN C C W+P+CG NG++Y+SACLAG
Sbjct: 409 TCENSSVVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAG 468
Query: 506 CQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTL 565
C+TS +G N++F NC+C+ SGNSS ++G C K C M YFL++S ++S+
Sbjct: 469 CETSIGTGINMVFQNCSCI----QTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIY 524
Query: 566 SLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCG 625
SL IPGY++LLRC+K + KS +G++T RV AGIPAP+YFG L+D++CL WG +CG
Sbjct: 525 SLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCG 584
Query: 626 SRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKK 666
G+CR+YDS FR+IYLGL L S + ++ +L +L+K
Sbjct: 585 ESGACRIYDSTTFRYIYLGLPAALRGSSFVPALIILILLRK 625
>gi|19913403 organic anion transporting polypeptide A [Homo sapiens]
Length = 670
Score = 615 bits (1586), Expect = e-176
Identities = 295/641 (46%), Positives = 426/641 (66%), Gaps = 18/641 (2%)
Query: 26 KTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVID 85
+TE + C +LK+FL A++ + +K L+ Y+ S +TQIER+F+IP+SLVG I+
Sbjct: 3 ETEKRIETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFIN 62
Query: 86 GSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSS 145
GSFEIGNLL+I FVSYFG KLHRP +IG GCV+MG+G L ++P F M QY+YE S
Sbjct: 63 GSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVS 122
Query: 146 NSTLSISPCLLESSSQLPVSVMEKSKSKISNECEVDTSSSMWIYVFLGNLLRGIGETPIQ 205
+ S S +E+ +Q+ + S EC + S MW+YV +GN++RG+GETPI
Sbjct: 123 GNLSSNSFLCMENGTQILRPTQDPS------ECTKEVKSLMWVYVLVGNIVRGMGETPIL 176
Query: 206 PLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITP 265
PLGI+Y++DFA +N+ YIG V+T AIIGP+ G LL S CA +YVD GFVN D + ITP
Sbjct: 177 PLGISYIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITP 236
Query: 266 KDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDY 325
D +WVGAWW G+LI +++L A+PF++LP +LP+ +++ I +++ D
Sbjct: 237 TDTRWVGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNAD-------IIKNENEDK 289
Query: 326 QTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYG 385
Q + + K + +DFLP +K+L NP+Y L++ S +QFN+ M+++ PKY+EQQYG
Sbjct: 290 QKEEVKKEKY-GITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYG 348
Query: 386 QSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFAL 445
SSS A F++G+ N+P + +G GG++MKKF+I+V AA + S+ YLL+ F +
Sbjct: 349 ISSSDAIFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLM 408
Query: 446 GCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAG 505
CENS V G+ SY+G Y E +F+DCN C C W+P+CG NG++Y+SACLAG
Sbjct: 409 TCENSSVVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAG 468
Query: 506 CQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTL 565
C+TS +G N++F NC+C+ SGNSS ++G C K C M YFL++S ++S+
Sbjct: 469 CETSIGTGINMVFQNCSCI----QTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIY 524
Query: 566 SLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCG 625
SL IPGY++LLRC+K + KS +G++T RV AGIPAP+YFG L+D++CL WG +CG
Sbjct: 525 SLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCG 584
Query: 626 SRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKK 666
G+CR+YDS FR+IYLGL L S + ++ +L +L+K
Sbjct: 585 ESGACRIYDSTTFRYIYLGLPAALRGSSFVPALIILILLRK 625
>gi|116812593 liver-specific organic anion transporter 3TM12 [Homo
sapiens]
Length = 640
Score = 563 bits (1451), Expect = e-160
Identities = 271/613 (44%), Positives = 408/613 (66%), Gaps = 15/613 (2%)
Query: 63 LKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVG 122
+K + TQIERRF+I SSLVG+IDGSFEIGNL VI FVSYFG+KLHRPK+IG GC +MG G
Sbjct: 1 MKISTTQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTG 60
Query: 123 TLLIAMPQFFMEQYKYERYS---PSSNSTLSISPCLLE---SSSQLPVSVMEKSKSKISN 176
++L+A+P FFM Y+Y + + PS NST ++ CL+ S ++ P ++E+
Sbjct: 61 SILMALPHFFMGYYRYSKETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERG------ 114
Query: 177 ECEVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGP 236
C ++ S MWIYVF+GN+LRGIGETPI PLGI+Y+DDFA E +++ Y+G V + + G
Sbjct: 115 -CVKESGSHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGL 173
Query: 237 IFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLP 296
+F F+LGSL AK+YVDIG+V+L I ITPKD +WVGAWWLG+L++GI+S+++++PF++LP
Sbjct: 174 VFAFMLGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLP 233
Query: 297 KSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYF 356
+ P +E S D I + F SLK++ NP+Y
Sbjct: 234 LN-PNKPQKERKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTNPLYV 292
Query: 357 LYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKK 416
+++ + + +S +TY K +EQQYG S+S+ NF++G++ +PAVA+G+FSGG ++KK
Sbjct: 293 IFVIFTLLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKK 352
Query: 417 FRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDC 476
F++S+ G AKL S+ L + F L CE+ VAGLT++Y G PV H S C
Sbjct: 353 FKLSLVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPLSYC 412
Query: 477 NSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSG 536
NS C C E++WEP+CG NGITY+S CLAGC++S+ + + I+FYNC+CV + ++ N S
Sbjct: 413 NSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFYNCSCVEVIGLQNKNYSA 472
Query: 537 IVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAI 596
+G C +D+ C + + VI V+ ++ ++G +L++R ++P+LK+ A+G +++ +
Sbjct: 473 HLGECPRDDACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIVQPELKALAIGFHSMIM 532
Query: 597 RVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTV-ILGTVSIL 655
R L GI P+YFG LIDT+C+KW CG+RG+CR+Y+S + GL V ++ V +L
Sbjct: 533 RSLGGILVPIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFGLKVALIFPVLVL 592
Query: 656 LSIAVLFILKKNY 668
L++ + + KK++
Sbjct: 593 LTVFIFVVRKKSH 605
>gi|222831575 solute carrier organic anion transporter family,
member 3A1 isoform 1 [Homo sapiens]
Length = 710
Score = 415 bits (1066), Expect = e-116
Identities = 228/674 (33%), Positives = 374/674 (55%), Gaps = 53/674 (7%)
Query: 33 EEKQPCCGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGN 92
++K C +K+FL + + A+ YL S +T +ERRF++ S+ VGVI SFEIGN
Sbjct: 30 KKKVSCFSNIKIFLVSECALMLAQGTVGAYLVSVLTTLERRFNLQSADVGVIASSFEIGN 89
Query: 93 LLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYE----RYSPSSNST 148
L +I FVSYFGA+ HRP++IG G ++M +G LL A+P+F QYKYE R+
Sbjct: 90 LALILFVSYFGARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEAGEIRWGAEGRDV 149
Query: 149 LSISPCLLESSSQLPVSVMEKSKSKISNECEVDTSSSMWIYVFLG-NLLRGIGETPIQPL 207
+ + + + C T+++M + +G +L GIG TP+QPL
Sbjct: 150 CAANGSGGDEGPDPDLI------------CRNRTATNMMYLLLIGAQVLLGIGATPVQPL 197
Query: 208 GIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKD 267
G++Y+DD +++ YIG + T+ + GP GF+LGS C K+YVD F++ ++ ITP D
Sbjct: 198 GVSYIDDHVRRKDSSLYIGILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDD 257
Query: 268 PQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQT 327
P+W+GAWW G+L+ G + +++ + P+SLP S + E + ++ + +Y+
Sbjct: 258 PRWIGAWWGGFLLCGALLFFSSLLMFGFPQSLP-----PHSEPAMESEQAMLSER-EYER 311
Query: 328 PQGEN------------AKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTY 375
P+ N A + R K+L NPV+ + + ++ + G +
Sbjct: 312 PKPSNGVLRHPLEPDSSASCFQQLRVIPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAF 371
Query: 376 KPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFG 435
KY+EQQ+ ++S AN ++G+ IP LGIF GG+++KK +S GA ++ + ++
Sbjct: 372 LGKYLEQQFNLTTSSANQLLGMTAIPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVS 431
Query: 436 YLLFLSLFALGCENSDVAGLTVSY-QGTKPVSYHERALFSDCNSRCKCSETKWEPMCGEN 494
++S LGC+ VAG+TV Y T P S + +S CN+ C+C + P+CG +
Sbjct: 432 TACYVSFLFLGCDTGPVAGVTVPYGNSTAPGSALDP--YSPCNNNCECQTDSFTPVCGAD 489
Query: 495 GITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYF 554
GITY+SAC AGC ++N +G C C+ ++ N++ + G+C GC + FL F
Sbjct: 490 GITYLSACFAGCNSTNLTG-------CACLTTVPAE--NATVVPGKCPSP-GCQEAFLTF 539
Query: 555 LVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDT 614
L + I S ++ P I+L+R + P+LKS+ALG+ L +R+L IP P+ FG ID+
Sbjct: 540 LCVMCICSLIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDS 599
Query: 615 SCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKKNYVSKHRS 674
+CL W CG +G+C LYD+ V+R++Y+ + + L + + +L L+KNY +
Sbjct: 600 TCLFWS-TFCGEQGACVLYDNVVYRYLYVSIAIALKSFAFILYTTTWQCLRKNY----KR 654
Query: 675 FITKRERTMVSTRF 688
+I E + ++ F
Sbjct: 655 YIKNHEGGLSTSEF 668
>gi|222831573 solute carrier organic anion transporter family,
member 3A1 isoform 2 [Homo sapiens]
Length = 692
Score = 414 bits (1065), Expect = e-115
Identities = 225/654 (34%), Positives = 366/654 (55%), Gaps = 49/654 (7%)
Query: 33 EEKQPCCGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGN 92
++K C +K+FL + + A+ YL S +T +ERRF++ S+ VGVI SFEIGN
Sbjct: 30 KKKVSCFSNIKIFLVSECALMLAQGTVGAYLVSVLTTLERRFNLQSADVGVIASSFEIGN 89
Query: 93 LLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYE----RYSPSSNST 148
L +I FVSYFGA+ HRP++IG G ++M +G LL A+P+F QYKYE R+
Sbjct: 90 LALILFVSYFGARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEAGEIRWGAEGRDV 149
Query: 149 LSISPCLLESSSQLPVSVMEKSKSKISNECEVDTSSSMWIYVFLG-NLLRGIGETPIQPL 207
+ + + + C T+++M + +G +L GIG TP+QPL
Sbjct: 150 CAANGSGGDEGPDPDLI------------CRNRTATNMMYLLLIGAQVLLGIGATPVQPL 197
Query: 208 GIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKD 267
G++Y+DD +++ YIG + T+ + GP GF+LGS C K+YVD F++ ++ ITP D
Sbjct: 198 GVSYIDDHVRRKDSSLYIGILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDD 257
Query: 268 PQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQT 327
P+W+GAWW G+L+ G + +++ + P+SLP S + E + ++ + +Y+
Sbjct: 258 PRWIGAWWGGFLLCGALLFFSSLLMFGFPQSLP-----PHSEPAMESEQAMLSER-EYER 311
Query: 328 PQGEN------------AKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTY 375
P+ N A + R K+L NPV+ + + ++ + G +
Sbjct: 312 PKPSNGVLRHPLEPDSSASCFQQLRVIPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAF 371
Query: 376 KPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFG 435
KY+EQQ+ ++S AN ++G+ IP LGIF GG+++KK +S GA ++ + ++
Sbjct: 372 LGKYLEQQFNLTTSSANQLLGMTAIPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVS 431
Query: 436 YLLFLSLFALGCENSDVAGLTVSY-QGTKPVSYHERALFSDCNSRCKCSETKWEPMCGEN 494
++S LGC+ VAG+TV Y T P S + +S CN+ C+C + P+CG +
Sbjct: 432 TACYVSFLFLGCDTGPVAGVTVPYGNSTAPGSALDP--YSPCNNNCECQTDSFTPVCGAD 489
Query: 495 GITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYF 554
GITY+SAC AGC ++N +G C C+ ++ N++ + G+C GC + FL F
Sbjct: 490 GITYLSACFAGCNSTNLTG-------CACLTTVPAE--NATVVPGKCPSP-GCQEAFLTF 539
Query: 555 LVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDT 614
L + I S ++ P I+L+R + P+LKS+ALG+ L +R+L IP P+ FG ID+
Sbjct: 540 LCVMCICSLIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDS 599
Query: 615 SCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKKNY 668
+CL W CG +G+C LYD+ V+R++Y+ + + L + + +L L+KNY
Sbjct: 600 TCLFWS-TFCGEQGACVLYDNVVYRYLYVSIAIALKSFAFILYTTTWQCLRKNY 652
>gi|188528663 solute carrier organic anion transporter family,
member 2A1 [Homo sapiens]
Length = 643
Score = 384 bits (986), Expect = e-106
Identities = 211/635 (33%), Positives = 339/635 (53%), Gaps = 39/635 (6%)
Query: 40 GELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFV 99
G +KVF+ + + L Y KS++T IE+RF + SS G+I EI N ++I FV
Sbjct: 29 GNIKVFVLCQGLLQLCQLLYSAYFKSSLTTIEKRFGLSSSSSGLISSLNEISNAILIIFV 88
Query: 100 SYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESS 159
SYFG+++HRP++IG G + + G ++ +P F E Y+Y S +NS L C +
Sbjct: 89 SYFGSRVHRPRLIGIGGLFLAAGAFILTLPHFLSEPYQYTLASTGNNSRLQAELCQ-KHW 147
Query: 160 SQLPVSVMEKSKSKISNECEVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASED 219
LP S + E +SSMW + + LL GIG PIQP GI+Y+DDF+
Sbjct: 148 QDLPPSKCHSTTQNPQKE-----TSSMWGLMVVAQLLAGIGTVPIQPFGISYVDDFSEPS 202
Query: 220 NAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYL 279
N+ YI + +++ GP FG+LLGS+ +++VD G VN + + P DP+W+GAWWLG L
Sbjct: 203 NSPLYISILFAISVFGPAFGYLLGSVMLQIFVDYGRVNTAAVNLVPGDPRWIGAWWLGLL 262
Query: 280 IAGIISLLAAVPFWYLPKSLP----RSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKI 335
I+ + +L + PF++ P+++P R+ + D E++K +
Sbjct: 263 ISSALLVLTSFPFFFFPRAMPIGAKRAPATADEARKLEEAK--------------SRGSL 308
Query: 336 MEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVI 395
++ + F L N ++ L + + + G+ T+ K++E+QYG S++ ANF+I
Sbjct: 309 VDFIKRFPCIFLRLLMNSLFVLVVLAQCTFSSVIAGLSTFLNKFLEKQYGTSAAYANFLI 368
Query: 396 GLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGL 455
G +N+PA ALG+ GGI+MK+F S+ ++ +L + LF +GC VA +
Sbjct: 369 GAVNLPAAALGMLFGGILMKRFVFSLQAIPRIATTIITISMILCVPLFFMGCSTPTVAEV 428
Query: 456 TVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRS--- 512
Y + S H ++ C C C ++ + P+CG+NGI Y+S C AGC N S
Sbjct: 429 ---YPPSTSSSIHPQS--PACRRDCSCPDSIFHPVCGDNGIEYLSPCHAGCSNINMSSAT 483
Query: 513 GKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPG 572
K +I+ NC+CV G++S G C C L + + S + P
Sbjct: 484 SKQLIYLNCSCV-----TGGSASAKTGSCPVP--CAHFLLPAIFLISFVSLIACISHNPL 536
Query: 573 YILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRL 632
Y+++LR + + KSFA+G+ L +R+LA +P+P +G+ ID SC++W G RG+C
Sbjct: 537 YMMVLRVVNQEEKSFAIGVQFLLMRLLAWLPSPALYGLTIDHSCIRWNSLCLGRRGACAY 596
Query: 633 YDSNVFRHIYLGLTVILGTVSILLSIAVLFILKKN 667
YD++ R YLGL + + +LL + + +KKN
Sbjct: 597 YDNDALRDRYLGLQMGYKALGMLLLCFISWRVKKN 631
>gi|223634012 solute carrier organic anion transporter family,
member 2B1 isoform 2 [Homo sapiens]
Length = 687
Score = 352 bits (904), Expect = 5e-97
Identities = 206/647 (31%), Positives = 342/647 (52%), Gaps = 41/647 (6%)
Query: 42 LKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSY 101
+K+F+ S + A+ + GYLKS+I+ +E+RF + S G++ E+GN +I FVSY
Sbjct: 26 IKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFVSY 85
Query: 102 FGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSSN-STLSISPCLLESSS 160
FG+++HRP++IG G +++ + LL+ +P F E Y+Y+ SP S CL +S+
Sbjct: 86 FGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSA 145
Query: 161 QLPVSVMEKSKSKISNECEVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDN 220
P S S S+ E S + I +F+ L G+G PIQP GI+Y+DDFA N
Sbjct: 146 --PASA--PSNGNCSSYTETQHLSVVGI-MFVAQTLLGVGGVPIQPFGISYIDDFAHNSN 200
Query: 221 AAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLI 280
+ Y+G + V ++GP F LGSL +LYVDI + I++T KDP+WVGAWWLG+LI
Sbjct: 201 SPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLI 260
Query: 281 AGIISLLAAVPFWYLPKSLPR----------------SQSREDSNSSSEKSKFIIDDHTD 324
A LAA+P+++ PK +P+ S +R+ +S S++S D
Sbjct: 261 AAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQD 320
Query: 325 YQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQY 384
N +++ + F L +P++ L + + + GM T+ PK++E+Q+
Sbjct: 321 GLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQF 380
Query: 385 GQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFA 444
++S AN +IG ++ P+V +GI GG+++K+ + G L L + L LF
Sbjct: 381 SITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFF 440
Query: 445 LGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCG-ENGITYVSACL 503
+GC + +AG+T + ++ L C C C + P+C + Y++ C
Sbjct: 441 IGCSSHQIAGIT-----HQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCH 495
Query: 504 AGCQT----SNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISV 559
AGC + + + NC+CV GN + G C D+ C + + FL++
Sbjct: 496 AGCSSWVVQDALDNSQVFYTNCSCV-----VEGNPV-LAGSC--DSTCSHLVVPFLLLVS 547
Query: 560 ITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKW 619
+ S L P ++L+LR +K + K+ A+GI + +R+LA +P+PV G IDT+C+ W
Sbjct: 548 LGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHW 607
Query: 620 GFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKK 666
CG R CR Y++++ R+ ++GL T S++ VL +L++
Sbjct: 608 ALS-CGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQ 653
>gi|6005820 solute carrier organic anion transporter family, member
2B1 isoform 1 [Homo sapiens]
Length = 709
Score = 352 bits (904), Expect = 5e-97
Identities = 206/647 (31%), Positives = 342/647 (52%), Gaps = 41/647 (6%)
Query: 42 LKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSY 101
+K+F+ S + A+ + GYLKS+I+ +E+RF + S G++ E+GN +I FVSY
Sbjct: 48 IKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFVSY 107
Query: 102 FGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSSN-STLSISPCLLESSS 160
FG+++HRP++IG G +++ + LL+ +P F E Y+Y+ SP S CL +S+
Sbjct: 108 FGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSA 167
Query: 161 QLPVSVMEKSKSKISNECEVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDN 220
P S S S+ E S + I +F+ L G+G PIQP GI+Y+DDFA N
Sbjct: 168 --PASA--PSNGNCSSYTETQHLSVVGI-MFVAQTLLGVGGVPIQPFGISYIDDFAHNSN 222
Query: 221 AAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLI 280
+ Y+G + V ++GP F LGSL +LYVDI + I++T KDP+WVGAWWLG+LI
Sbjct: 223 SPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLI 282
Query: 281 AGIISLLAAVPFWYLPKSLPR----------------SQSREDSNSSSEKSKFIIDDHTD 324
A LAA+P+++ PK +P+ S +R+ +S S++S D
Sbjct: 283 AAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQD 342
Query: 325 YQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQY 384
N +++ + F L +P++ L + + + GM T+ PK++E+Q+
Sbjct: 343 GLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQF 402
Query: 385 GQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFA 444
++S AN +IG ++ P+V +GI GG+++K+ + G L L + L LF
Sbjct: 403 SITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFF 462
Query: 445 LGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCG-ENGITYVSACL 503
+GC + +AG+T + ++ L C C C + P+C + Y++ C
Sbjct: 463 IGCSSHQIAGIT-----HQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCH 517
Query: 504 AGCQT----SNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISV 559
AGC + + + NC+CV GN + G C D+ C + + FL++
Sbjct: 518 AGCSSWVVQDALDNSQVFYTNCSCV-----VEGNPV-LAGSC--DSTCSHLVVPFLLLVS 569
Query: 560 ITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKW 619
+ S L P ++L+LR +K + K+ A+GI + +R+LA +P+PV G IDT+C+ W
Sbjct: 570 LGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHW 629
Query: 620 GFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKK 666
CG R CR Y++++ R+ ++GL T S++ VL +L++
Sbjct: 630 ALS-CGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQ 675
>gi|38679890 solute carrier organic anion transporter family, member
4C1 [Homo sapiens]
Length = 724
Score = 325 bits (832), Expect = 1e-88
Identities = 183/615 (29%), Positives = 317/615 (51%), Gaps = 51/615 (8%)
Query: 58 LAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCV 117
+ G + +I+ +E+R+++ SSL G+I S++I L+ FVS+FG + H+P+ +
Sbjct: 121 VVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFCLLSLFVSFFGERGHKPRWLAFAAF 180
Query: 118 IMGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNE 177
++G+G L+ ++PQFF +YK +L C+ ++ S
Sbjct: 181 MIGLGALVFSLPQFFSGEYKL--------GSLFEDTCVT---------------TRNSTS 217
Query: 178 CEVDTSS-SMWIYVF-LGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIG 235
C TSS S ++YVF LG LL G G TP+ LG A+LDD ++ YIG ++I+G
Sbjct: 218 CTSSTSSLSNYLYVFILGQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIGTGYAMSILG 277
Query: 236 PIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYL 295
P G++LG +Y+D+ + +T DP+W+GAWW+G+L++ I + +PF
Sbjct: 278 PAIGYVLGGQLLTIYIDVAMG--ESTDVTEDDPRWLGAWWIGFLLSWIFAWSLIIPFSCF 335
Query: 296 PKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVY 355
PK LP + + +S +Q+ + K + +DF +LKNL N V+
Sbjct: 336 PKHLPGTAEIQAGKTSQA-----------HQSNSNADVKFGKSIKDFPAALKNLMKNAVF 384
Query: 356 FLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMK 415
+ +++ + G T+ PK+IE Q+G +SS A + G + IP ALG GG ++
Sbjct: 385 MCLVLSTSSEALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPGAALGQILGGFLVS 444
Query: 416 KFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSD 475
KFR++ K L +S L CEN AG++ SY GT + L +
Sbjct: 445 KFRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGTGELGN----LIAP 500
Query: 476 CNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVG-----IAASK 530
CN+ C CS + + P+CG+ G+ Y S C AGC K ++YNC+C+ + ++
Sbjct: 501 CNANCNCSRSYYYPVCGD-GVQYFSPCFAGCSNPVAHRKPKVYYNCSCIERKTEITSTAE 559
Query: 531 SGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALG 590
+ G+C+ C ++ ++ + ++ +T + G P + +LRC+ + +S ALG
Sbjct: 560 TFGFEAKAGKCETH--CAKLPIFLCIFFIVIIFTF-MAGTPITVSILRCVNHRQRSLALG 616
Query: 591 IYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVILG 650
I + +R+L IP P+ FG ID++C+ W CG +G+C +YD+ H+ + ++V
Sbjct: 617 IQFMVLRLLGTIPGPIIFGFTIDSTCILWDINDCGIKGACWIYDNIKMAHMLVAISVTCK 676
Query: 651 TVSILLSIAVLFILK 665
+++ + +F+ K
Sbjct: 677 VITMFFNGFAIFLYK 691
>gi|225637473 solute carrier organic anion transporter family,
member 5A1 isoform 1 [Homo sapiens]
Length = 848
Score = 318 bits (816), Expect = 8e-87
Identities = 200/670 (29%), Positives = 320/670 (47%), Gaps = 83/670 (12%)
Query: 43 KVFLCALSFVYFAKAL-AEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSY 101
+ FL + F+ F +AL GYL S IT IERR+ + SS G++ F+IGNL+V+ FVSY
Sbjct: 128 RCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSY 187
Query: 102 FGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSS---------NSTLSIS 152
FG + RP + G +++ G L A+P F Y+ + + S+ NST ++
Sbjct: 188 FGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLE 247
Query: 153 PCLLESSSQLPVSVMEKSKSKISNECEVDTS-SSMWIYVFL---GNLLRGIGETPIQPLG 208
P C D+ ++ W+YV L +L G+G TPI LG
Sbjct: 248 P----------------------PACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLG 285
Query: 209 IAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDP 268
YLDD ++N++ Y+ + + +GP G+LLG L YVD + + + DP
Sbjct: 286 PTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDP 341
Query: 269 QWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTD---- 324
+++G WW G+L+ I L P + PK LP ++ +K KF +D +D
Sbjct: 342 RFIGNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKK------KKKKFSVDAVSDDDVL 395
Query: 325 ---YQTPQGENAKIMEMA-----RDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYK 376
+ + K+ M RD + + N + + T + + +T+
Sbjct: 396 KEKSNNSEQADKKVSSMGFGKDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFI 455
Query: 377 PKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGY 436
PK+IE Q+G +S A+ G+I +P+ +GI GG ++KK ++ +AKL + S
Sbjct: 456 PKFIESQFGIPASNASIYTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSL 515
Query: 437 LLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGI 496
L F +LF +GCE+ ++ G+ + Y ++ R L CN C C ++EP+CG +GI
Sbjct: 516 LCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGI 575
Query: 497 TYVSACLAGCQTSNRSGKNIIFY-NCTCVG--------------------IAASKSGNSS 535
TY + CLAGC S I Y CTCV + + N
Sbjct: 576 TYFNPCLAGCVNSGNLSTGIRNYTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGY 635
Query: 536 GIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLA 595
+ G+C++ C + FLV I ++ + I+ LR ++ + + FALG+ +
Sbjct: 636 AVSGKCKRT--C-NTLIPFLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVL 692
Query: 596 IRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSIL 655
+R LA IP P+YFG +IDT+C+ W + CG +GSC Y+ FR +Y GL L V +
Sbjct: 693 LRTLAYIPTPIYFGAVIDTTCMLWQ-QECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFI 751
Query: 656 LSIAVLFILK 665
+ +K
Sbjct: 752 FIFLAWYSIK 761
>gi|39777594 solute carrier organic anion transporter family member
4A1 [Homo sapiens]
Length = 722
Score = 311 bits (798), Expect = 1e-84
Identities = 190/623 (30%), Positives = 302/623 (48%), Gaps = 42/623 (6%)
Query: 45 FLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGA 104
FLCA +F+ G++ + IT +ERR+D+ S G+I S++I L +TFVSYFG
Sbjct: 108 FLCAAAFLQ--GMTVNGFINTVITSLERRYDLHSYQSGLIASSYDIAACLCLTFVSYFGG 165
Query: 105 KLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPV 164
H+P+ +G G ++MG G+L+ A+P F +Y+ E + + +S+S L
Sbjct: 166 SGHKPRWLGWGVLLMGTGSLVFALPHFTAGRYEVELDAGVRTCPANPGAVCADSTSGL-- 223
Query: 165 SVMEKSKSKISNECEVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFY 224
S + LG L G+G TP+ LG+ YLD+ + Y
Sbjct: 224 -------------------SRYQLVFMLGQFLHGVGATPLYTLGVTYLDENVKSSCSPVY 264
Query: 225 IGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGII 284
I T AI+GP G+L+G +Y ++G +T + P WVGAWW+G+L +G
Sbjct: 265 IAIFYTAAILGPAAGYLIGGALLNIYTEMG----RRTELTTESPLWVGAWWVGFLGSGAA 320
Query: 285 SLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLP 344
+ AVP P+ LP SQ ++ + D + N + RD
Sbjct: 321 AFFTAVPILGYPRQLPGSQRYAVMRAAE------MHQLKDSSRGEASNPDFGKTIRDLPL 374
Query: 345 SLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVA 404
S+ L NP + L + + GM T+ PK++E Q+ S+S A + G + +PA
Sbjct: 375 SIWLLLKNPTFILLCLAGATEATLITGMSTFSPKFLESQFSLSASEAATLFGYLVVPAGG 434
Query: 405 LGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKP 464
G F GG + K R+ K L +V LL + +F+L C + +AG+T SY G+
Sbjct: 435 GGTFLGGFFVNKLRLRGSAVIKFCLFCTVVS-LLGILVFSLHCPSVPMAGVTASYGGSLL 493
Query: 465 VSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKN--IIFYNCT 522
H L + CN+ C C + P+CG +G+ Y S C AGC + + + ++ +C+
Sbjct: 494 PEGHLN-LTAPCNAACSCQPEHYSPVCGSDGLMYFSLCHAGCPAATETNVDGQKVYRDCS 552
Query: 523 CVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKP 582
C+ S SG G+C + C + L + I V+ +T L IP LRC++
Sbjct: 553 CIPQNLS-SGFGHATAGKC--TSTCQRKPLLLVFIFVVIFFTF-LSSIPALTATLRCVRD 608
Query: 583 QLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIY 642
+SFALGI + +R+L GIP P+ FG +ID +CL W +CG +GSC +Y ++
Sbjct: 609 PQRSFALGIQWIVVRILGGIPGPIAFGWVIDKACLLWQ-DQCGQQGSCLVYQNSAMSRYI 667
Query: 643 LGLTVILGTVSILLSIAVLFILK 665
L + ++ + +L F+ K
Sbjct: 668 LIMGLLYKVLGVLFFAIACFLYK 690
>gi|225637475 solute carrier organic anion transporter family,
member 5A1 isoform 3 [Homo sapiens]
Length = 793
Score = 283 bits (725), Expect = 3e-76
Identities = 192/658 (29%), Positives = 301/658 (45%), Gaps = 114/658 (17%)
Query: 43 KVFLCALSFVYFAKAL-AEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSY 101
+ FL + F+ F +AL GYL S IT IERR+ + SS G++ F+IGNL+V+ FVSY
Sbjct: 128 RCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSY 187
Query: 102 FGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSS---------NSTLSIS 152
FG + RP + G +++ G L A+P F Y+ + + S+ NST ++
Sbjct: 188 FGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLE 247
Query: 153 PCLLESSSQLPVSVMEKSKSKISNECEVDTS-SSMWIYVFL---GNLLRGIGETPIQPLG 208
P C D+ ++ W+YV L +L G+G TPI LG
Sbjct: 248 P----------------------PACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLG 285
Query: 209 IAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDP 268
YLDD ++N++ Y+ + + +GP G+LLG L YVD + + + DP
Sbjct: 286 PTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDP 341
Query: 269 QWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTP 328
+++G WW G+L+ I L P + PK LP ++ +K KF +D +D
Sbjct: 342 RFIGNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKK------KKKKFSVDAVSDDDVL 395
Query: 329 QGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSS 388
+ E + E A + S+ FG V
Sbjct: 396 K-EKSNNSEQADKKVSSMG--FGKDVR--------------------------------- 419
Query: 389 SRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCE 448
G+I +P+ +GI GG ++KK ++ +AKL + S L F +LF +GCE
Sbjct: 420 -------GVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCE 472
Query: 449 NSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQT 508
+ ++ G+ + Y ++ R L CN C C ++EP+CG +GITY + CLAGC
Sbjct: 473 SINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVN 532
Query: 509 SNRSGKNIIFY-NCTCVG--------------------IAASKSGNSSGIVGRCQKDNGC 547
S I Y CTCV + + N + G+C++ C
Sbjct: 533 SGNLSTGIRNYTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRT--C 590
Query: 548 PQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVY 607
+ FLV I ++ + I+ LR ++ + + FALG+ + +R LA IP P+Y
Sbjct: 591 -NTLIPFLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIY 649
Query: 608 FGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILK 665
FG +IDT+C+ W + CG +GSC Y+ FR +Y GL L V + + +K
Sbjct: 650 FGAVIDTTCMLWQ-QECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIK 706
>gi|223634014 solute carrier organic anion transporter family,
member 2B1 isoform 3 [Homo sapiens]
Length = 565
Score = 270 bits (690), Expect = 3e-72
Identities = 155/498 (31%), Positives = 259/498 (52%), Gaps = 35/498 (7%)
Query: 190 VFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKL 249
+F+ L G+G PIQP GI+Y+DDFA N+ Y+G + V ++GP F LGSL +L
Sbjct: 48 MFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRL 107
Query: 250 YVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPR-------- 301
YVDI + I++T KDP+WVGAWWLG+LIA LAA+P+++ PK +P+
Sbjct: 108 YVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFR 167
Query: 302 --------SQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNP 353
S +R+ +S S++S D N +++ + F L +P
Sbjct: 168 RKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHP 227
Query: 354 VYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIV 413
++ L + + + GM T+ PK++E+Q+ ++S AN +IG ++ P+V +GI GG++
Sbjct: 228 IFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVL 287
Query: 414 MKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALF 473
+K+ + G L L + L LF +GC + +AG+T + ++ L
Sbjct: 288 VKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGIT-----HQTSAHPGLELS 342
Query: 474 SDCNSRCKCSETKWEPMCG-ENGITYVSACLAGCQT----SNRSGKNIIFYNCTCVGIAA 528
C C C + P+C + Y++ C AGC + + + NC+CV
Sbjct: 343 PSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCV---- 398
Query: 529 SKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFA 588
GN + G C D+ C + + FL++ + S L P ++L+LR +K + K+ A
Sbjct: 399 -VEGNPV-LAGSC--DSTCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLA 454
Query: 589 LGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVI 648
+GI + +R+LA +P+PV G IDT+C+ W CG R CR Y++++ R+ ++GL
Sbjct: 455 VGIQFMFLRILAWMPSPVIHGSAIDTTCVHWALS-CGRRAVCRYYNNDLLRNRFIGLQFF 513
Query: 649 LGTVSILLSIAVLFILKK 666
T S++ VL +L++
Sbjct: 514 FKTGSVICFALVLAVLRQ 531
>gi|225637477 solute carrier organic anion transporter family,
member 5A1 isoform 2 [Homo sapiens]
Length = 687
Score = 259 bits (661), Expect = 8e-69
Identities = 157/509 (30%), Positives = 248/509 (48%), Gaps = 59/509 (11%)
Query: 43 KVFLCALSFVYFAKAL-AEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSY 101
+ FL + F+ F +AL GYL S IT IERR+ + SS G++ F+IGNL+V+ FVSY
Sbjct: 128 RCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSY 187
Query: 102 FGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSS---------NSTLSIS 152
FG + RP + G +++ G L A+P F Y+ + + S+ NST ++
Sbjct: 188 FGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLE 247
Query: 153 PCLLESSSQLPVSVMEKSKSKISNECEVDTS-SSMWIYVFL---GNLLRGIGETPIQPLG 208
P C D+ ++ W+YV L +L G+G TPI LG
Sbjct: 248 P----------------------PACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLG 285
Query: 209 IAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDP 268
YLDD ++N++ Y+ + + +GP G+LLG L YVD + + + DP
Sbjct: 286 PTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDP 341
Query: 269 QWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTD---- 324
+++G WW G+L+ I L P + PK LP ++ +K KF +D +D
Sbjct: 342 RFIGNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKK------KKKKFSVDAVSDDDVL 395
Query: 325 ---YQTPQGENAKIMEMA-----RDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYK 376
+ + K+ M RD + + N + + T + + +T+
Sbjct: 396 KEKSNNSEQADKKVSSMGFGKDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFI 455
Query: 377 PKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGY 436
PK+IE Q+G +S A+ G+I +P+ +GI GG ++KK ++ +AKL + S
Sbjct: 456 PKFIESQFGIPASNASIYTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSL 515
Query: 437 LLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGI 496
L F +LF +GCE+ ++ G+ + Y ++ R L CN C C ++EP+CG +GI
Sbjct: 516 LCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGI 575
Query: 497 TYVSACLAGCQTSNRSGKNIIFY-NCTCV 524
TY + CLAGC S I Y CTCV
Sbjct: 576 TYFNPCLAGCVNSGNLSTGIRNYTECTCV 604
>gi|93277099 solute carrier organic anion transporter family, member
6A1 [Homo sapiens]
Length = 719
Score = 224 bits (571), Expect = 2e-58
Identities = 146/639 (22%), Positives = 285/639 (44%), Gaps = 56/639 (8%)
Query: 38 CCGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVIT 97
CC ++ F+ + + + G + +I ++ + + + ++ S++I + LV
Sbjct: 101 CCNNIRCFMIFYCILLICQGVVFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAI 160
Query: 98 FVSYFGAKLHRPKIIG--AGCVIMGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCL 155
F++++G R K+I A ++G+G+LL A P +
Sbjct: 161 FIAFYG---DRKKVIWFVASSFLIGLGSLLCAFPS------------------------I 193
Query: 156 LESSSQLPVSVMEKSKS-KISNECE---VDTSSSMWIYVFLGNLLRGIGETPIQPLGIAY 211
E + Q V + + + K+ + C+ + S + LG ++GI P+ LGI +
Sbjct: 194 NEENKQSKVGIEDICEEIKVVSGCQSSGISFQSKYLSFFILGQTVQGIAGMPLYILGITF 253
Query: 212 LDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWV 271
+D+ + +A Y+G + ++IG G++LG+ K V + + T+ P+W+
Sbjct: 254 IDENVATHSAGIYLGIAECTSMIGYALGYVLGAPLVK--VPENTTSATNTTVNNGSPEWL 311
Query: 272 GAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGE 331
WW+ +L A +++ +P P ++P S + + K D +
Sbjct: 312 WTWWINFLFAAVVAWCTLIPLSCFPNNMPGSTRIK---ARKRKQLHFFDSRL-------K 361
Query: 332 NAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRA 391
+ K+ +D +L L NPV + ++ + G + P Y+E Q+ + + A
Sbjct: 362 DLKLGTNIKDLCAALWILMKNPVLICLALSKATEYLVIIGASEFLPIYLENQFILTPTVA 421
Query: 392 NFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSD 451
+ GL+ IP ALG GG+++ +S + + +SV +L + + + C
Sbjct: 422 TTLAGLVLIPGGALGQLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQ 481
Query: 452 VAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNR 511
AG+ Y GT + L + CN +C+CS + + +CG + I Y S C AGC S
Sbjct: 482 FAGINEDYDGTGKLGN----LTAPCNEKCRCSSSIYSSICGRDDIEYFSPCFAGCTYSKA 537
Query: 512 SGKNIIFYNCTCVG---IAASKSGNS-SGIVGRCQKDNGCPQMFLYFLVISVITSYTLSL 567
+ ++YNC+C+ I A G+ G+C +F+ F+ ++I S
Sbjct: 538 QNQKKMYYNCSCIKEGLITADAEGDFIDARPGKCDAKCYKLPLFIAFIFSTLIFS---GF 594
Query: 568 GGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSR 627
G+P + + R + +L+S ALG+ + +R+ IP P F + +TSC+ +CG
Sbjct: 595 SGVPIVLAMTRVVPDKLRSLALGVSYVILRIFGTIPGPSIFKMSGETSCILRDVNKCGHT 654
Query: 628 GSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKK 666
G C +Y+ + +G+ + +I+ + FI K+
Sbjct: 655 GRCWIYNKTKMAFLLVGICFLCKLCTIIFTTIAFFIYKR 693
>gi|11863156 RECK protein precursor [Homo sapiens]
Length = 971
Score = 36.6 bits (83), Expect = 0.083
Identities = 14/27 (51%), Positives = 21/27 (77%), Gaps = 1/27 (3%)
Query: 480 CKCSETKWEPMCGENGITYVSACLAGC 506
C C++ ++ P+CG+NG TY SAC+A C
Sbjct: 633 CNCAD-QFVPVCGQNGRTYPSACIARC 658
Score = 33.5 bits (75), Expect = 0.70
Identities = 25/77 (32%), Positives = 35/77 (45%), Gaps = 13/77 (16%)
Query: 455 LTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGK 514
L YQ K +SY C C+ +E P+CG NG TY S C A S+R
Sbjct: 734 LCTLYQRGKSLSYK-----GPCQPFCRATE----PVCGHNGETYSSVCAA---YSDRVAV 781
Query: 515 NIIFYNCTCVGIAASKS 531
+ + +C VG+ + S
Sbjct: 782 D-YYGDCQAVGVLSEHS 797
>gi|42741679 ATPase, H+ transporting, lysosomal V0 subunit A2 [Homo
sapiens]
Length = 856
Score = 32.3 bits (72), Expect = 1.6
Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 4/68 (5%)
Query: 390 RANFVIGLINIP-AVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLF---AL 445
+ + ++G+I++ V LGIF+ KKF I + +L +FGYL+F+ +
Sbjct: 553 KMSVILGIIHMTFGVILGIFNHLHFRKKFNIYLVSIPELLFMLCIFGYLIFMIFYKWLVF 612
Query: 446 GCENSDVA 453
E S VA
Sbjct: 613 SAETSRVA 620
>gi|9945322 solute carrier family 17, member 7 [Homo sapiens]
Length = 560
Score = 32.0 bits (71), Expect = 2.0
Identities = 25/106 (23%), Positives = 45/106 (42%), Gaps = 6/106 (5%)
Query: 292 FWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFG 351
FWYL L +S S SE+ + I+D GE+AK+M F + F
Sbjct: 247 FWYLFWLLVSYESPALHPSISEEERKYIEDAI------GESAKLMNPLTKFSTPWRRFFT 300
Query: 352 NPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGL 397
+ + + + + + + ++ +P Y E+ +G S+ V L
Sbjct: 301 SMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGLVSAL 346
>gi|12383051 transmembrane protein with EGF-like and two
follistatin-like domains 2 [Homo sapiens]
Length = 374
Score = 30.8 bits (68), Expect = 4.5
Identities = 13/39 (33%), Positives = 20/39 (51%), Gaps = 3/39 (7%)
Query: 476 CNSRCKCSETKWEPMCGENGITYVSACL---AGCQTSNR 511
C CS+T + P+C +G +Y +AC A CQ +
Sbjct: 180 CVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEK 218
>gi|54873613 agrin [Homo sapiens]
Length = 2045
Score = 30.4 bits (67), Expect = 5.9
Identities = 11/26 (42%), Positives = 19/26 (73%), Gaps = 3/26 (11%)
Query: 480 CKCSE---TKWEPMCGENGITYVSAC 502
C+C + + ++P+CG +G+TY SAC
Sbjct: 488 CECLQACSSLYDPVCGSDGVTYGSAC 513
>gi|15451844 ADAM metallopeptidase domain 19 preproprotein [Homo
sapiens]
Length = 918
Score = 30.4 bits (67), Expect = 5.9
Identities = 36/144 (25%), Positives = 65/144 (45%), Gaps = 18/144 (12%)
Query: 289 AVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGE----NAKIMEMAR---D 341
A+ F K PR RED NS +++ D+ ++Q + + K++E+A
Sbjct: 187 ALQFTQQTKKRPRRMKREDLNSMKYVELYLVADYLEFQKNRRDQDATKHKLIEIANYVDK 246
Query: 342 FLPSLK---NLFGNPVY-FLYLC-TSTVQFNSLFGMVTYKPKYIEQQYGQSS------SR 390
F SL L G V+ +C S +++L+ ++++ K + Q+Y ++ S
Sbjct: 247 FYRSLNIRIALVGLEVWTHGNMCEVSENPYSTLWSFLSWRRKLLAQKYHDNAQLITGMSF 306
Query: 391 ANFVIGLINIPAVALGIFSGGIVM 414
IGL + A+ SGG+ M
Sbjct: 307 HGTTIGLAPLMAMCSVYQSGGVNM 330
>gi|156104876 fms-related tyrosine kinase 1 isoform 1 precursor
[Homo sapiens]
Length = 1338
Score = 30.0 bits (66), Expect = 7.8
Identities = 17/70 (24%), Positives = 29/70 (41%), Gaps = 4/70 (5%)
Query: 491 CGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQM 550
CG NG + S +N +G FY+C + + SK + + D G P +
Sbjct: 81 CGRNGKQFCSTLTLNTAQANHTG----FYSCKYLAVPTSKKKETESAIYIFISDTGRPFV 136
Query: 551 FLYFLVISVI 560
+Y + +I
Sbjct: 137 EMYSEIPEII 146
>gi|229892220 fms-related tyrosine kinase 1 isoform 2 precursor
[Homo sapiens]
Length = 687
Score = 30.0 bits (66), Expect = 7.8
Identities = 17/70 (24%), Positives = 29/70 (41%), Gaps = 4/70 (5%)
Query: 491 CGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQM 550
CG NG + S +N +G FY+C + + SK + + D G P +
Sbjct: 81 CGRNGKQFCSTLTLNTAQANHTG----FYSCKYLAVPTSKKKETESAIYIFISDTGRPFV 136
Query: 551 FLYFLVISVI 560
+Y + +I
Sbjct: 137 EMYSEIPEII 146
>gi|229892302 fms-related tyrosine kinase 1 isoform 4 precursor
[Homo sapiens]
Length = 541
Score = 30.0 bits (66), Expect = 7.8
Identities = 17/70 (24%), Positives = 29/70 (41%), Gaps = 4/70 (5%)
Query: 491 CGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQM 550
CG NG + S +N +G FY+C + + SK + + D G P +
Sbjct: 81 CGRNGKQFCSTLTLNTAQANHTG----FYSCKYLAVPTSKKKETESAIYIFISDTGRPFV 136
Query: 551 FLYFLVISVI 560
+Y + +I
Sbjct: 137 EMYSEIPEII 146
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.139 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,710,263
Number of Sequences: 37866
Number of extensions: 1119884
Number of successful extensions: 2698
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 2583
Number of HSP's gapped (non-prelim): 50
length of query: 712
length of database: 18,247,518
effective HSP length: 109
effective length of query: 603
effective length of database: 14,120,124
effective search space: 8514434772
effective search space used: 8514434772
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.