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Search of human proteins with 83700233
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|83700233 eukaryotic translation initiation factor 3, subunit
C [Homo sapiens]
(913 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|83700233 eukaryotic translation initiation factor 3, subunit ... 1824 0.0
gi|4503525 eukaryotic translation initiation factor 3, subunit C... 1824 0.0
gi|153791492 eukaryotic translation initiation factor 3, subunit... 1819 0.0
gi|55956788 nucleolin [Homo sapiens] 73 1e-12
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 65 2e-10
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 65 2e-10
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 63 1e-09
gi|11225260 DNA topoisomerase I [Homo sapiens] 62 3e-09
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 61 5e-09
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 61 5e-09
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 61 5e-09
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] 61 5e-09
gi|217330641 IWS1 homolog [Homo sapiens] 58 4e-08
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 57 6e-08
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 57 8e-08
gi|221219020 NYD-SP11 protein [Homo sapiens] 57 1e-07
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] 56 1e-07
gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H... 56 2e-07
gi|115529449 upstream binding transcription factor, RNA polymera... 56 2e-07
gi|115529451 upstream binding transcription factor, RNA polymera... 56 2e-07
gi|7657671 upstream binding transcription factor, RNA polymerase... 56 2e-07
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 55 4e-07
gi|38569484 kinesin family member 21A [Homo sapiens] 55 4e-07
gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi... 54 5e-07
gi|31317305 M-phase phosphoprotein 10 [Homo sapiens] 54 7e-07
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 54 7e-07
gi|4557509 cylicin 2 [Homo sapiens] 54 9e-07
gi|157674363 protein phosphatase 1, regulatory subunit 15A [Homo... 54 9e-07
gi|197927454 DEK oncogene isoform 2 [Homo sapiens] 54 9e-07
gi|4503249 DEK oncogene isoform 1 [Homo sapiens] 54 9e-07
>gi|83700233 eukaryotic translation initiation factor 3, subunit C
[Homo sapiens]
Length = 913
Score = 1824 bits (4724), Expect = 0.0
Identities = 913/913 (100%), Positives = 913/913 (100%)
Query: 1 MSRFFTTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEEL 60
MSRFFTTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEEL
Sbjct: 1 MSRFFTTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEEL 60
Query: 61 TNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNEL 120
TNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNEL
Sbjct: 61 TNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNEL 120
Query: 121 WEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEG 180
WEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEG
Sbjct: 121 WEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEG 180
Query: 181 SSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDS 240
SSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDS
Sbjct: 181 SSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDS 240
Query: 241 DSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNEGGE 300
DSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNEGGE
Sbjct: 241 DSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNEGGE 300
Query: 301 WERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQI 360
WERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQI
Sbjct: 301 WERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQI 360
Query: 361 AAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIFV 420
AAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIFV
Sbjct: 361 AAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIFV 420
Query: 421 GENILEESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVC 480
GENILEESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVC
Sbjct: 421 GENILEESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVC 480
Query: 481 AIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDYKAHQRQLTPPEGSSKSEQDQAENE 540
AIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDYKAHQRQLTPPEGSSKSEQDQAENE
Sbjct: 481 AIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDYKAHQRQLTPPEGSSKSEQDQAENE 540
Query: 541 GEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQH 600
GEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQH
Sbjct: 541 GEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQH 600
Query: 601 ADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQ 660
ADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQ
Sbjct: 601 ADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQ 660
Query: 661 EQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLRV 720
EQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLRV
Sbjct: 661 EQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLRV 720
Query: 721 GERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLV 780
GERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLV
Sbjct: 721 GERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLV 780
Query: 781 RKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQ 840
RKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQ
Sbjct: 781 RKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQ 840
Query: 841 TVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQGTYGGYFRDQKDGYRKNEGYMR 900
TVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQGTYGGYFRDQKDGYRKNEGYMR
Sbjct: 841 TVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQGTYGGYFRDQKDGYRKNEGYMR 900
Query: 901 RGGYRQQQSQTAY 913
RGGYRQQQSQTAY
Sbjct: 901 RGGYRQQQSQTAY 913
>gi|4503525 eukaryotic translation initiation factor 3, subunit C
[Homo sapiens]
Length = 913
Score = 1824 bits (4724), Expect = 0.0
Identities = 913/913 (100%), Positives = 913/913 (100%)
Query: 1 MSRFFTTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEEL 60
MSRFFTTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEEL
Sbjct: 1 MSRFFTTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEEL 60
Query: 61 TNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNEL 120
TNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNEL
Sbjct: 61 TNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNEL 120
Query: 121 WEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEG 180
WEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEG
Sbjct: 121 WEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEG 180
Query: 181 SSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDS 240
SSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDS
Sbjct: 181 SSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDS 240
Query: 241 DSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNEGGE 300
DSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNEGGE
Sbjct: 241 DSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNEGGE 300
Query: 301 WERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQI 360
WERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQI
Sbjct: 301 WERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQI 360
Query: 361 AAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIFV 420
AAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIFV
Sbjct: 361 AAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIFV 420
Query: 421 GENILEESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVC 480
GENILEESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVC
Sbjct: 421 GENILEESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVC 480
Query: 481 AIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDYKAHQRQLTPPEGSSKSEQDQAENE 540
AIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDYKAHQRQLTPPEGSSKSEQDQAENE
Sbjct: 481 AIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDYKAHQRQLTPPEGSSKSEQDQAENE 540
Query: 541 GEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQH 600
GEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQH
Sbjct: 541 GEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQH 600
Query: 601 ADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQ 660
ADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQ
Sbjct: 601 ADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQ 660
Query: 661 EQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLRV 720
EQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLRV
Sbjct: 661 EQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLRV 720
Query: 721 GERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLV 780
GERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLV
Sbjct: 721 GERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLV 780
Query: 781 RKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQ 840
RKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQ
Sbjct: 781 RKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQ 840
Query: 841 TVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQGTYGGYFRDQKDGYRKNEGYMR 900
TVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQGTYGGYFRDQKDGYRKNEGYMR
Sbjct: 841 TVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQGTYGGYFRDQKDGYRKNEGYMR 900
Query: 901 RGGYRQQQSQTAY 913
RGGYRQQQSQTAY
Sbjct: 901 RGGYRQQQSQTAY 913
>gi|153791492 eukaryotic translation initiation factor 3, subunit
C-like [Homo sapiens]
Length = 914
Score = 1819 bits (4712), Expect = 0.0
Identities = 913/914 (99%), Positives = 913/914 (99%), Gaps = 1/914 (0%)
Query: 1 MSRFFTTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEEL 60
MSRFFTTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEEL
Sbjct: 1 MSRFFTTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEEL 60
Query: 61 TNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNEL 120
TNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNEL
Sbjct: 61 TNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNEL 120
Query: 121 WEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEG 180
WEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEG
Sbjct: 121 WEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEG 180
Query: 181 SSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDS 240
SSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDS
Sbjct: 181 SSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDS 240
Query: 241 DSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEE-DNEGG 299
DSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEE DNEGG
Sbjct: 241 DSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEEDNEGG 300
Query: 300 EWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQ 359
EWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQ
Sbjct: 301 EWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQ 360
Query: 360 IAAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIF 419
IAAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIF
Sbjct: 361 IAAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIF 420
Query: 420 VGENILEESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQV 479
VGENILEESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQV
Sbjct: 421 VGENILEESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQV 480
Query: 480 CAIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDYKAHQRQLTPPEGSSKSEQDQAEN 539
CAIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDYKAHQRQLTPPEGSSKSEQDQAEN
Sbjct: 481 CAIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDYKAHQRQLTPPEGSSKSEQDQAEN 540
Query: 540 EGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQ 599
EGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQ
Sbjct: 541 EGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQ 600
Query: 600 HADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERN 659
HADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERN
Sbjct: 601 HADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERN 660
Query: 660 QEQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLR 719
QEQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLR
Sbjct: 661 QEQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLR 720
Query: 720 VGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTML 779
VGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTML
Sbjct: 721 VGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTML 780
Query: 780 VRKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPT 839
VRKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPT
Sbjct: 781 VRKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPT 840
Query: 840 QTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQGTYGGYFRDQKDGYRKNEGYM 899
QTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQGTYGGYFRDQKDGYRKNEGYM
Sbjct: 841 QTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQGTYGGYFRDQKDGYRKNEGYM 900
Query: 900 RRGGYRQQQSQTAY 913
RRGGYRQQQSQTAY
Sbjct: 901 RRGGYRQQQSQTAY 914
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 73.2 bits (178), Expect = 1e-12
Identities = 49/176 (27%), Positives = 85/176 (48%), Gaps = 19/176 (10%)
Query: 160 KQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDED 219
K++ ++ D+D+E++EED E DEDEDED + A +K + AP+ E +D++
Sbjct: 142 KEDSDEEEDDDSEEDEEDDE---DEDEDEDEIEPAA-MKAAAAAPASED-------EDDE 190
Query: 220 EDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAK 279
+D +D +DD+D + S ++ +GK+ A K DED++ ++ +D
Sbjct: 191 DDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDD 250
Query: 280 KKHDRKSKRLDEEEEDNE--------GGEWERVRGGVPLVKEKPKMFAKGTEITHA 327
+ + DEEEE+ E G+ ++ E K +GTE T A
Sbjct: 251 EDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTA 306
Score = 42.0 bits (97), Expect = 0.003
Identities = 31/115 (26%), Positives = 49/115 (42%), Gaps = 15/115 (13%)
Query: 203 APSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPT 262
A ++ K KK D ++E+ +DSE+DE+ D + + E K A A +
Sbjct: 131 AKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDE 190
Query: 263 TDEDKKAAEKKRED---------------KAKKKHDRKSKRLDEEEEDNEGGEWE 302
DED + + ED KA K K+K + E+E++ E E E
Sbjct: 191 DDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDE 245
Score = 37.0 bits (84), Expect = 0.084
Identities = 28/100 (28%), Positives = 42/100 (42%), Gaps = 17/100 (17%)
Query: 199 KKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLK 258
KK A + K K ED D E+ +D E+ D D +E+E + A +
Sbjct: 124 KKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEE----DEEDDEDEDEDEDEIEPAAMKAAA 179
Query: 259 KAPTT-DEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNE 297
AP + DED + E +D D+EE+D+E
Sbjct: 180 AAPASEDEDDEDDEDDEDDD------------DDEEDDSE 207
Score = 35.4 bits (80), Expect = 0.24
Identities = 33/142 (23%), Positives = 57/142 (40%), Gaps = 8/142 (5%)
Query: 169 EDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFL----KKMDDEDEDSED 224
++ E++ ED E S DE++D G KK +A + ++K + KK+ +
Sbjct: 22 KEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAKKVVVSPTKKVAVATPAKKA 81
Query: 225 S----EDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKK 280
+ + T + + + GK+ A + L P A+ + K K
Sbjct: 82 AVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAAIPAKGAKNGKNAK 141
Query: 281 KHDRKSKRLDEEEEDNEGGEWE 302
K D + D+ EED E E E
Sbjct: 142 KEDSDEEEDDDSEEDEEDDEDE 163
Score = 32.3 bits (72), Expect = 2.1
Identities = 22/118 (18%), Positives = 53/118 (44%), Gaps = 1/118 (0%)
Query: 112 DLEDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDA 171
D +D +E ED + ++ + + +A+ T K +K + + ++ ++ D++
Sbjct: 186 DEDDEDDEDDEDDDDDEE-DDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDED 244
Query: 172 EKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDE 229
E +++D + D+DED++ + EAP ++ K+ + + E E
Sbjct: 245 EDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTE 302
Score = 31.6 bits (70), Expect = 3.5
Identities = 22/77 (28%), Positives = 34/77 (44%), Gaps = 6/77 (7%)
Query: 200 KSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRF--- 256
K+ G+ +K + +EDSED E ED + S+ + +++GK+ A S
Sbjct: 6 KAGKNQGDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAKKVV 65
Query: 257 ---LKKAPTTDEDKKAA 270
KK KKAA
Sbjct: 66 VSPTKKVAVATPAKKAA 82
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 65.5 bits (158), Expect = 2e-10
Identities = 49/153 (32%), Positives = 74/153 (48%), Gaps = 15/153 (9%)
Query: 160 KQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKK---SEAPSGESRKFLKKMD 216
KQN E DE+A KN+ +SE SD +E + L+ K S+ SGE +K K
Sbjct: 1267 KQNEENPGDEEA-KNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEH 1325
Query: 217 DEDE-------DSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKA 269
E + SEDSED + ++G + S+SE+E+ +T R KKA + +
Sbjct: 1326 KEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRT----RSAKKAELEENQRSY 1381
Query: 270 AEKKREDKAKKKHDRKSKRLDEEEEDNEGGEWE 302
+KK+ + K + D S+ EE+ E E E
Sbjct: 1382 KQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEE 1414
Score = 42.4 bits (98), Expect = 0.002
Identities = 47/188 (25%), Positives = 81/188 (43%), Gaps = 20/188 (10%)
Query: 131 NKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDG 190
++N+ S+ QKI+ + ++S+ + S DE K+ + D+D D +
Sbjct: 1174 DQNSIGEGSSDEQKIKPVTENLV--LSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPEN 1231
Query: 191 VSAATFLKKKSEAPSGESRKFLKKMDDEDED--------SEDSEDDEDWDTGSTSSDSDS 242
A L ++ +A DDE E+ +E++ DE+ +S+SDS
Sbjct: 1232 RIAKKMLLEEIKANLSSDED--GSSDDEPEEGKKRTGKQNEENPGDEE-AKNQVNSESDS 1288
Query: 243 EEEEGKQTALASRFLKKAPTTD-----EDKKAAEKKREDKAKKKHDRKSKRLDEEEED-N 296
+ EE K+ R L+ T E+KK K+ ++ K ++ RK D E+ D
Sbjct: 1289 DSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKE-VKGRNRRKVSSEDSEDSDFQ 1347
Query: 297 EGGEWERV 304
E G E V
Sbjct: 1348 ESGVSEEV 1355
Score = 42.0 bits (97), Expect = 0.003
Identities = 56/291 (19%), Positives = 114/291 (39%), Gaps = 31/291 (10%)
Query: 18 SGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNAMKIRDVT 77
SG+E ++K V P+ + +D++D R AK EE+ + + + +
Sbjct: 1207 SGDEALSKSV-------PVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPE 1259
Query: 78 KCLE-----------EFELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNELWEDKEG 126
+ + + E + ++ S ++ PR+ R+L + E E
Sbjct: 1260 EGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDG--ESGEE 1317
Query: 127 KKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDEDE 186
KK K + + R+K+ + + +S + E S ED ++ S ++ +E
Sbjct: 1318 KKTKPKEHKEVKGRNRRKVSSEDSE-DSDFQESGVSEEVSESEDEQRPRTRSAKKAELEE 1376
Query: 187 DEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEE 246
++ KK+ E K + E+E+ E E++E+ + + EE+E
Sbjct: 1377 NQRSYKQK---KKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEE-----EEEEEEEEEDE 1428
Query: 247 GKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNE 297
+ + KK +D K + A K+ + + KR+ E E + E
Sbjct: 1429 NDDSKSPGKGRKKIRKILKDDKL--RTETQNALKEEEERRKRIAERERERE 1477
Score = 41.6 bits (96), Expect = 0.003
Identities = 43/220 (19%), Positives = 95/220 (43%), Gaps = 15/220 (6%)
Query: 122 EDKEGKKKMNKNNAKALSTLRQ-KIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEG 180
ED++ + + A+ R K +K R + S +N S +E+ EK EE+ E
Sbjct: 1359 EDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEE 1418
Query: 181 SSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSED--DEDWDTGSTSS 238
+E+E+ED S++P G+ RK ++K+ +D+ ++++ E+ + +
Sbjct: 1419 EEEEEEEEDE-------NDDSKSP-GKGRKKIRKILKDDKLRTETQNALKEEEERRKRIA 1470
Query: 239 DSDSEEEEGKQT-ALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNE 297
+ + E E+ ++ + K P T + +++ ++ + H +L + D
Sbjct: 1471 EREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGV 1530
Query: 298 GGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEIL 337
W+ V K+ P G + H + + K +++
Sbjct: 1531 QFMWDCCCESVKKTKKSP---GSGCILAHCMGLGKTLQVV 1567
Score = 40.8 bits (94), Expect = 0.006
Identities = 51/183 (27%), Positives = 86/183 (46%), Gaps = 16/183 (8%)
Query: 128 KKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDE--- 184
KK N S+ +K K D + H + K + E S+D DAE+ +E SS E
Sbjct: 800 KKRIPNTKDFDSSEDEKHSKKGMDNQGH-KNLKTSQEGSSD-DAERKQERETFSSAEGTV 857
Query: 185 DEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEE 244
D+D + L KK +A + S + K+ +++ E + +T S ++
Sbjct: 858 DKDTTIMELRDRLPKKQQASA--STDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKT 915
Query: 245 EEGKQTAL---ASRFLKKAP---TTDEDKKAAEKKREDKAKKKHDRKSK--RLDEEEEDN 296
+ Q L A +FLKK T+++DKK ++K E+K KK D K K +++++ E +
Sbjct: 916 CKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEK-KKPSDFKKKVIKMEQQYESS 974
Query: 297 EGG 299
G
Sbjct: 975 SDG 977
Score = 37.0 bits (84), Expect = 0.084
Identities = 56/299 (18%), Positives = 106/299 (35%), Gaps = 74/299 (24%)
Query: 114 EDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSA------ 167
+D +E ED + + K K S ++K+ K + +ES ++ PE+
Sbjct: 933 KDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPK 992
Query: 168 --------------------DEDAEKNEEDSE---------GSSDEDEDEDGVSAATFLK 198
D+ ++K +E S+ S D ED+ + A +
Sbjct: 993 GIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGRE 1052
Query: 199 KK------------SEAPSGESRKFLKKMDD--------------EDEDSEDSEDDEDWD 232
KK + S ++ K+ K D E + + ++
Sbjct: 1053 KKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQ 1112
Query: 233 TGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEE 292
+GS+SSD++ E+ K+ + KKA E K+ R +K+ D S +
Sbjct: 1113 SGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKR--NSLRTSTKRKQADITSSSSSDI 1170
Query: 293 EEDNEGGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQI 351
E+D++ E G K KP +T +V+ Q+ G + ++ +
Sbjct: 1171 EDDDQNSIGE---GSSDEQKIKP--------VTENLVLSSHTGFCQSSGDEALSKSVPV 1218
Score = 33.5 bits (75), Expect = 0.93
Identities = 59/303 (19%), Positives = 115/303 (37%), Gaps = 37/303 (12%)
Query: 18 SGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNAMKIRDVT 77
S +E +K N G + L S+ E + R + + F + M++RD
Sbjct: 812 SEDEKHSKKGMDNQGHKNLKTSQ-EGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRL 870
Query: 78 KCLEEFEL----LGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNELWEDKEGKKKMNKN 133
++ + K GK +S E +R +A+ ++ + K K K K
Sbjct: 871 PKKQQASASTDGVDKLSGKEQSFTSLE------VRKVAETKE------KSKHLKTKTCKK 918
Query: 134 NAKALSTLRQKIRKYNRDFESHITSYKQNP----EQSADEDAEKN--------EEDSEGS 181
LS + +K K ++ E+ KQ+ E+ D +K E S+G+
Sbjct: 919 VQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGT 978
Query: 182 SDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSD 241
E E+ +K+ + +K K D + ++ D + TG S
Sbjct: 979 EKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDS 1038
Query: 242 SEEEEGKQTALA-----SRFLKKAPTTDEDKKAAEKKR---EDKAKKKHDRKSKRLDEEE 293
SE+++ K A + L K+ +D +++ ++ ++ D++ KR++ E
Sbjct: 1039 SEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRE 1098
Query: 294 EDN 296
N
Sbjct: 1099 RRN 1101
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 65.5 bits (158), Expect = 2e-10
Identities = 49/153 (32%), Positives = 74/153 (48%), Gaps = 15/153 (9%)
Query: 160 KQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKK---SEAPSGESRKFLKKMD 216
KQN E DE+A KN+ +SE SD +E + L+ K S+ SGE +K K
Sbjct: 1305 KQNEENPGDEEA-KNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEH 1363
Query: 217 DEDE-------DSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKA 269
E + SEDSED + ++G + S+SE+E+ +T R KKA + +
Sbjct: 1364 KEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRT----RSAKKAELEENQRSY 1419
Query: 270 AEKKREDKAKKKHDRKSKRLDEEEEDNEGGEWE 302
+KK+ + K + D S+ EE+ E E E
Sbjct: 1420 KQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEE 1452
Score = 42.4 bits (98), Expect = 0.002
Identities = 47/188 (25%), Positives = 81/188 (43%), Gaps = 20/188 (10%)
Query: 131 NKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDG 190
++N+ S+ QKI+ + ++S+ + S DE K+ + D+D D +
Sbjct: 1212 DQNSIGEGSSDEQKIKPVTENLV--LSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPEN 1269
Query: 191 VSAATFLKKKSEAPSGESRKFLKKMDDEDED--------SEDSEDDEDWDTGSTSSDSDS 242
A L ++ +A DDE E+ +E++ DE+ +S+SDS
Sbjct: 1270 RIAKKMLLEEIKANLSSDED--GSSDDEPEEGKKRTGKQNEENPGDEE-AKNQVNSESDS 1326
Query: 243 EEEEGKQTALASRFLKKAPTTD-----EDKKAAEKKREDKAKKKHDRKSKRLDEEEED-N 296
+ EE K+ R L+ T E+KK K+ ++ K ++ RK D E+ D
Sbjct: 1327 DSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKE-VKGRNRRKVSSEDSEDSDFQ 1385
Query: 297 EGGEWERV 304
E G E V
Sbjct: 1386 ESGVSEEV 1393
Score = 42.0 bits (97), Expect = 0.003
Identities = 56/291 (19%), Positives = 114/291 (39%), Gaps = 31/291 (10%)
Query: 18 SGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNAMKIRDVT 77
SG+E ++K V P+ + +D++D R AK EE+ + + + +
Sbjct: 1245 SGDEALSKSV-------PVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPE 1297
Query: 78 KCLE-----------EFELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNELWEDKEG 126
+ + + E + ++ S ++ PR+ R+L + E E
Sbjct: 1298 EGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDG--ESGEE 1355
Query: 127 KKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDEDE 186
KK K + + R+K+ + + +S + E S ED ++ S ++ +E
Sbjct: 1356 KKTKPKEHKEVKGRNRRKVSSEDSE-DSDFQESGVSEEVSESEDEQRPRTRSAKKAELEE 1414
Query: 187 DEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEE 246
++ KK+ E K + E+E+ E E++E+ + + EE+E
Sbjct: 1415 NQRSYKQK---KKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEE-----EEEEEEEEEDE 1466
Query: 247 GKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNE 297
+ + KK +D K + A K+ + + KR+ E E + E
Sbjct: 1467 NDDSKSPGKGRKKIRKILKDDKL--RTETQNALKEEEERRKRIAERERERE 1515
Score = 41.6 bits (96), Expect = 0.003
Identities = 43/220 (19%), Positives = 95/220 (43%), Gaps = 15/220 (6%)
Query: 122 EDKEGKKKMNKNNAKALSTLRQ-KIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEG 180
ED++ + + A+ R K +K R + S +N S +E+ EK EE+ E
Sbjct: 1397 EDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEE 1456
Query: 181 SSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSED--DEDWDTGSTSS 238
+E+E+ED S++P G+ RK ++K+ +D+ ++++ E+ + +
Sbjct: 1457 EEEEEEEEDE-------NDDSKSP-GKGRKKIRKILKDDKLRTETQNALKEEEERRKRIA 1508
Query: 239 DSDSEEEEGKQT-ALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNE 297
+ + E E+ ++ + K P T + +++ ++ + H +L + D
Sbjct: 1509 EREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGV 1568
Query: 298 GGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEIL 337
W+ V K+ P G + H + + K +++
Sbjct: 1569 QFMWDCCCESVKKTKKSP---GSGCILAHCMGLGKTLQVV 1605
Score = 40.8 bits (94), Expect = 0.006
Identities = 51/183 (27%), Positives = 86/183 (46%), Gaps = 16/183 (8%)
Query: 128 KKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDE--- 184
KK N S+ +K K D + H + K + E S+D DAE+ +E SS E
Sbjct: 838 KKRIPNTKDFDSSEDEKHSKKGMDNQGH-KNLKTSQEGSSD-DAERKQERETFSSAEGTV 895
Query: 185 DEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEE 244
D+D + L KK +A + S + K+ +++ E + +T S ++
Sbjct: 896 DKDTTIMELRDRLPKKQQASA--STDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKT 953
Query: 245 EEGKQTAL---ASRFLKKAP---TTDEDKKAAEKKREDKAKKKHDRKSK--RLDEEEEDN 296
+ Q L A +FLKK T+++DKK ++K E+K KK D K K +++++ E +
Sbjct: 954 CKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEK-KKPSDFKKKVIKMEQQYESS 1012
Query: 297 EGG 299
G
Sbjct: 1013 SDG 1015
Score = 37.0 bits (84), Expect = 0.084
Identities = 56/299 (18%), Positives = 106/299 (35%), Gaps = 74/299 (24%)
Query: 114 EDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSA------ 167
+D +E ED + + K K S ++K+ K + +ES ++ PE+
Sbjct: 971 KDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPK 1030
Query: 168 --------------------DEDAEKNEEDSE---------GSSDEDEDEDGVSAATFLK 198
D+ ++K +E S+ S D ED+ + A +
Sbjct: 1031 GIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGRE 1090
Query: 199 KK------------SEAPSGESRKFLKKMDD--------------EDEDSEDSEDDEDWD 232
KK + S ++ K+ K D E + + ++
Sbjct: 1091 KKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQ 1150
Query: 233 TGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEE 292
+GS+SSD++ E+ K+ + KKA E K+ R +K+ D S +
Sbjct: 1151 SGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKR--NSLRTSTKRKQADITSSSSSDI 1208
Query: 293 EEDNEGGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQI 351
E+D++ E G K KP +T +V+ Q+ G + ++ +
Sbjct: 1209 EDDDQNSIGE---GSSDEQKIKP--------VTENLVLSSHTGFCQSSGDEALSKSVPV 1256
Score = 33.5 bits (75), Expect = 0.93
Identities = 59/303 (19%), Positives = 115/303 (37%), Gaps = 37/303 (12%)
Query: 18 SGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNAMKIRDVT 77
S +E +K N G + L S+ E + R + + F + M++RD
Sbjct: 850 SEDEKHSKKGMDNQGHKNLKTSQ-EGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRL 908
Query: 78 KCLEEFEL----LGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNELWEDKEGKKKMNKN 133
++ + K GK +S E +R +A+ ++ + K K K K
Sbjct: 909 PKKQQASASTDGVDKLSGKEQSFTSLE------VRKVAETKE------KSKHLKTKTCKK 956
Query: 134 NAKALSTLRQKIRKYNRDFESHITSYKQNP----EQSADEDAEKN--------EEDSEGS 181
LS + +K K ++ E+ KQ+ E+ D +K E S+G+
Sbjct: 957 VQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGT 1016
Query: 182 SDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSD 241
E E+ +K+ + +K K D + ++ D + TG S
Sbjct: 1017 EKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDS 1076
Query: 242 SEEEEGKQTALA-----SRFLKKAPTTDEDKKAAEKKR---EDKAKKKHDRKSKRLDEEE 293
SE+++ K A + L K+ +D +++ ++ ++ D++ KR++ E
Sbjct: 1077 SEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRE 1136
Query: 294 EDN 296
N
Sbjct: 1137 RRN 1139
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 62.8 bits (151), Expect = 1e-09
Identities = 63/219 (28%), Positives = 90/219 (41%), Gaps = 52/219 (23%)
Query: 113 LEDYLNE---LWED--------KEGKK-------KMNKNNAKALSTLRQKIRKYNRDFES 154
++DYLN WE+ K G K KMN+N K L R+K+ N
Sbjct: 30 IQDYLNRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSK 89
Query: 155 HITSYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKK-------------S 201
K+ ++S + + DS SS + EDE+ KKK S
Sbjct: 90 KRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHES 149
Query: 202 EAPSGESRKFLKKMDDEDEDSED----------SEDDEDWDTGSTSSDSDSEEEEGKQTA 251
E+ S ES K KK DE E +D S D+ + +SS+SD EE+
Sbjct: 150 ESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQ---- 205
Query: 252 LASRFLKKAPTTDEDKKAAE--KKREDKAKKKHDRKSKR 288
KK +E ++A E KK++ K KKH +K K+
Sbjct: 206 -----AKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKK 239
Score = 31.2 bits (69), Expect = 4.6
Identities = 19/107 (17%), Positives = 48/107 (44%)
Query: 210 KFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKA 269
K L + +++ ++ E ++ + + ++S S++ E K+ + ++ D +
Sbjct: 56 KALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSS 115
Query: 270 AEKKREDKAKKKHDRKSKRLDEEEEDNEGGEWERVRGGVPLVKEKPK 316
+ ED+ KK+ R+ K+ + + ++ E VK+K K
Sbjct: 116 SSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKK 162
>gi|11225260 DNA topoisomerase I [Homo sapiens]
Length = 765
Score = 61.6 bits (148), Expect = 3e-09
Identities = 51/190 (26%), Positives = 85/190 (44%), Gaps = 22/190 (11%)
Query: 122 EDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGS 181
+D+E K N + + ++K + ++D S +++ ++ D D EK +E+ +
Sbjct: 42 KDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSS-----EKHKDKHKDRDKEKRKEEKVRA 96
Query: 182 SDE----DEDEDGVSAATFLKKKSE-----APSGESRKFLKKMDDEDEDSEDSEDDEDWD 232
S + E E+G S+ +K + E P E K LK+ DED+ + + D
Sbjct: 97 SGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTED 156
Query: 233 TGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEE 292
T EEE+GK LKK D+DKK E + K KK + + + EE
Sbjct: 157 TKKEKKRKLEEEEDGK--------LKKPKNKDKDKKVPEPDNKKKKPKKEEEQKWKWWEE 208
Query: 293 EEDNEGGEWE 302
E EG +W+
Sbjct: 209 ERYPEGIKWK 218
Score = 32.7 bits (73), Expect = 1.6
Identities = 28/113 (24%), Positives = 53/113 (46%), Gaps = 7/113 (6%)
Query: 219 DEDSEDSEDDEDWDTGSTSSDSDS--EEEEGKQTALASRFLKKAPTTDEDKKAAEKKRED 276
D DS+ + D+ + D + E + + +K+ ++ + K +EKK ++
Sbjct: 4 DHLHNDSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKE 63
Query: 277 KAKKKH-DRKSKRLDE--EEEDNEGGEWERVR--GGVPLVKEKPKMFAKGTEI 324
K K KH D S++ + ++ D E + E+VR G + KEK F+ +I
Sbjct: 64 KEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQI 116
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 60.8 bits (146), Expect = 5e-09
Identities = 48/197 (24%), Positives = 95/197 (48%), Gaps = 25/197 (12%)
Query: 124 KEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEK--NEEDSEGS 181
KE KKK KN+ + ++ N++ E + K++ E +++++++ +E+ SE
Sbjct: 501 KESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDG 560
Query: 182 SDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGS------ 235
S+ + +E+G+ +K G ++ + + D++ + DSE+ E D GS
Sbjct: 561 SEREFEENGL-------EKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDE 613
Query: 236 ----TSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKRE--DKAKKKHDRKSKRL 289
D DS+E+E ++ F ++ ++++ A EK E DK ++ D K
Sbjct: 614 EGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLF 673
Query: 290 ----DEEEEDNEGGEWE 302
D+E+ED +G E E
Sbjct: 674 EESDDKEDEDADGKEVE 690
Score = 49.7 bits (117), Expect = 1e-05
Identities = 56/224 (25%), Positives = 94/224 (41%), Gaps = 30/224 (13%)
Query: 114 EDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYN-----RDFESHITSYKQNPEQSAD 168
ED LN+ E++ G K ++ + + K + R+FE + + E S
Sbjct: 522 EDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEK 581
Query: 169 E------DAEKNEEDSEGSSDEDE------DEDGVSAATFLKKKSEAPSGESRKFLKKMD 216
E D E E DSE S ED+ DE+G + + S+ E + K D
Sbjct: 582 ELHENVLDKELEENDSENSEFEDDGSEKVLDEEG--SEREFDEDSDEKEEEEDTYEKVFD 639
Query: 217 DEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKRED 276
DE ++ ED E + + G ++D +EE + + F + DED E + D
Sbjct: 640 DESDEKEDEEYAD--EKGLEAADKKAEEGDADE----KLFEESDDKEDEDADGKEVEDAD 693
Query: 277 KAKKKHDRKSKRLDEEEEDN-----EGGEWERVRGGVPLVKEKP 315
+ + D +++L +EEED+ + + GG V+E P
Sbjct: 694 EKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLGGFGSVEEGP 737
Score = 44.7 bits (104), Expect = 4e-04
Identities = 36/144 (25%), Positives = 63/144 (43%), Gaps = 16/144 (11%)
Query: 158 SYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDD 217
S + +P++ + + KN+ + G + E ED+ L K+SE G ++ +
Sbjct: 494 SEEDSPKKESKKKTLKNDCEENGLAKESEDD--------LNKESEEEVGPTK-------E 538
Query: 218 EDEDSEDSEDDEDWDTGSTSSDSDSE-EEEGKQTALASRFLKKAPTTDEDKKAAEKKRED 276
+ED + E DED + S+ E EE G + L +K + K E+ +
Sbjct: 539 SEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSE 598
Query: 277 KAKKKHDRKSKRLDEEEEDNEGGE 300
++ + D K LDEE + E E
Sbjct: 599 NSEFEDDGSEKVLDEEGSEREFDE 622
>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 60.8 bits (146), Expect = 5e-09
Identities = 48/197 (24%), Positives = 95/197 (48%), Gaps = 25/197 (12%)
Query: 124 KEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEK--NEEDSEGS 181
KE KKK KN+ + ++ N++ E + K++ E +++++++ +E+ SE
Sbjct: 501 KESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDG 560
Query: 182 SDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGS------ 235
S+ + +E+G+ +K G ++ + + D++ + DSE+ E D GS
Sbjct: 561 SEREFEENGL-------EKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDE 613
Query: 236 ----TSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKRE--DKAKKKHDRKSKRL 289
D DS+E+E ++ F ++ ++++ A EK E DK ++ D K
Sbjct: 614 EGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLF 673
Query: 290 ----DEEEEDNEGGEWE 302
D+E+ED +G E E
Sbjct: 674 EESDDKEDEDADGKEVE 690
Score = 49.7 bits (117), Expect = 1e-05
Identities = 56/224 (25%), Positives = 94/224 (41%), Gaps = 30/224 (13%)
Query: 114 EDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYN-----RDFESHITSYKQNPEQSAD 168
ED LN+ E++ G K ++ + + K + R+FE + + E S
Sbjct: 522 EDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEK 581
Query: 169 E------DAEKNEEDSEGSSDEDE------DEDGVSAATFLKKKSEAPSGESRKFLKKMD 216
E D E E DSE S ED+ DE+G + + S+ E + K D
Sbjct: 582 ELHENVLDKELEENDSENSEFEDDGSEKVLDEEG--SEREFDEDSDEKEEEEDTYEKVFD 639
Query: 217 DEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKRED 276
DE ++ ED E + + G ++D +EE + + F + DED E + D
Sbjct: 640 DESDEKEDEEYAD--EKGLEAADKKAEEGDADE----KLFEESDDKEDEDADGKEVEDAD 693
Query: 277 KAKKKHDRKSKRLDEEEEDN-----EGGEWERVRGGVPLVKEKP 315
+ + D +++L +EEED+ + + GG V+E P
Sbjct: 694 EKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLGGFGSVEEGP 737
Score = 44.7 bits (104), Expect = 4e-04
Identities = 36/144 (25%), Positives = 63/144 (43%), Gaps = 16/144 (11%)
Query: 158 SYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDD 217
S + +P++ + + KN+ + G + E ED+ L K+SE G ++ +
Sbjct: 494 SEEDSPKKESKKKTLKNDCEENGLAKESEDD--------LNKESEEEVGPTK-------E 538
Query: 218 EDEDSEDSEDDEDWDTGSTSSDSDSE-EEEGKQTALASRFLKKAPTTDEDKKAAEKKRED 276
+ED + E DED + S+ E EE G + L +K + K E+ +
Sbjct: 539 SEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSE 598
Query: 277 KAKKKHDRKSKRLDEEEEDNEGGE 300
++ + D K LDEE + E E
Sbjct: 599 NSEFEDDGSEKVLDEEGSEREFDE 622
>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
Length = 237
Score = 60.8 bits (146), Expect = 5e-09
Identities = 53/199 (26%), Positives = 87/199 (43%), Gaps = 35/199 (17%)
Query: 108 RILADLEDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSA 167
+ LA+ E+ +NE W KK++ K+ K LS +K R K+ +
Sbjct: 46 KALAEFEEKMNENW-----KKELEKHREKLLSGSESSSKKRQR-------KKKEKKKSGR 93
Query: 168 DEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEA-PSGESRKFLKKMDDEDEDSEDSE 226
+ + DS SS + EDED KKK+ + S ES M + + DS+DS
Sbjct: 94 YSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSES-----SMSETESDSKDSL 148
Query: 227 DDEDWDTGSTSSDSD-----------SEEEEGKQTALA-SRFL-----KKAPTTDEDKKA 269
+ T + D SE++ +L+ S ++ KK +++E +KA
Sbjct: 149 KKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKA 208
Query: 270 AEKKREDKAKKKHDRKSKR 288
EK ++ K KKH +K K+
Sbjct: 209 TEKTKKKKKHKKHSKKKKK 227
Score = 40.8 bits (94), Expect = 0.006
Identities = 43/190 (22%), Positives = 71/190 (37%), Gaps = 47/190 (24%)
Query: 113 LEDYLNE---LWEDKEGKKKMNKNNAKALSTLRQKIRK-YNRDFESHITSYKQNPEQSAD 168
++DYLN WE+ + + + K +KAL+ +K+ + + ++ E H E S+
Sbjct: 20 IQDYLNRPRPTWEEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSK 79
Query: 169 EDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDD 228
+ K +E KKKS S S S DS
Sbjct: 80 KRQRKKKE---------------------KKKSGRYSSSS-----------SSSSDS--- 104
Query: 229 EDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKR 288
SS S E+E K+ + K + +E + + K K +KSK
Sbjct: 105 --------SSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKD 156
Query: 289 LDEEEEDNEG 298
E+E+D +G
Sbjct: 157 GTEKEKDIKG 166
>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
Length = 247
Score = 60.8 bits (146), Expect = 5e-09
Identities = 53/199 (26%), Positives = 87/199 (43%), Gaps = 35/199 (17%)
Query: 108 RILADLEDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSA 167
+ LA+ E+ +NE W KK++ K+ K LS +K R K+ +
Sbjct: 56 KALAEFEEKMNENW-----KKELEKHREKLLSGSESSSKKRQR-------KKKEKKKSGR 103
Query: 168 DEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEA-PSGESRKFLKKMDDEDEDSEDSE 226
+ + DS SS + EDED KKK+ + S ES M + + DS+DS
Sbjct: 104 YSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSES-----SMSETESDSKDSL 158
Query: 227 DDEDWDTGSTSSDSD-----------SEEEEGKQTALA-SRFL-----KKAPTTDEDKKA 269
+ T + D SE++ +L+ S ++ KK +++E +KA
Sbjct: 159 KKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKA 218
Query: 270 AEKKREDKAKKKHDRKSKR 288
EK ++ K KKH +K K+
Sbjct: 219 TEKTKKKKKHKKHSKKKKK 237
Score = 40.8 bits (94), Expect = 0.006
Identities = 43/190 (22%), Positives = 71/190 (37%), Gaps = 47/190 (24%)
Query: 113 LEDYLNE---LWEDKEGKKKMNKNNAKALSTLRQKIRK-YNRDFESHITSYKQNPEQSAD 168
++DYLN WE+ + + + K +KAL+ +K+ + + ++ E H E S+
Sbjct: 30 IQDYLNRPRPTWEEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSK 89
Query: 169 EDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDD 228
+ K +E KKKS S S S DS
Sbjct: 90 KRQRKKKE---------------------KKKSGRYSSSS-----------SSSSDS--- 114
Query: 229 EDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKR 288
SS S E+E K+ + K + +E + + K K +KSK
Sbjct: 115 --------SSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKD 166
Query: 289 LDEEEEDNEG 298
E+E+D +G
Sbjct: 167 GTEKEKDIKG 176
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 58.2 bits (139), Expect = 4e-08
Identities = 45/154 (29%), Positives = 68/154 (44%), Gaps = 17/154 (11%)
Query: 159 YKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDE 218
+KQ PE D D E ED+E +D + + +KK + E + K+ D
Sbjct: 323 HKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMD-----RKKFHSSDSEEEEHKKQKMDS 377
Query: 219 DEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDED----------KK 268
DED ++ E +E + SDSE+EE K +A SR + A +D D K
Sbjct: 378 DEDEKEGE-EEKVAKRKAAVLSDSEDEE-KASAKKSRVVSDADDSDSDAVSDKSGKREKT 435
Query: 269 AAEKKREDKAKKKHDRKSKRLDEEEEDNEGGEWE 302
A E+ K+ D+K++ D D+E G E
Sbjct: 436 IASDSEEEAGKELSDKKNEEKDLFGSDSESGNEE 469
Score = 44.7 bits (104), Expect = 4e-04
Identities = 38/146 (26%), Positives = 65/146 (44%), Gaps = 7/146 (4%)
Query: 153 ESHITSYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFL 212
+SH+ K + S +E+ +K + DS+ E E+E + SE S K
Sbjct: 352 DSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKS 411
Query: 213 KKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEK 272
+ + D D+ D+ D+ T + SDSEEE GK+ L+ + ++ D ++ +
Sbjct: 412 RVVSDADDSDSDAVSDKSGKREKTIA-SDSEEEAGKE--LSDKKNEEKDLFGSDSESGNE 468
Query: 273 KREDKAKKKHDRKSKRLDEEEEDNEG 298
+ A D + DEEEE+ G
Sbjct: 469 EENLIA----DIFGESGDEEEEEFTG 490
Score = 43.1 bits (100), Expect = 0.001
Identities = 44/165 (26%), Positives = 63/165 (38%), Gaps = 31/165 (18%)
Query: 149 NRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPS--- 205
+ D H S +N E ++ ED + D + + + +SE P
Sbjct: 252 SEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGP 311
Query: 206 -------GESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSD----------SDSEEEEGK 248
SR K D+D D E+ +D + S SD SDSEEEE K
Sbjct: 312 ASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEHK 371
Query: 249 QTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEE 293
K+ +DED+K E+ E AK+K S DEE+
Sbjct: 372 ---------KQKMDSDEDEKEGEE--EKVAKRKAAVLSDSEDEEK 405
Score = 40.0 bits (92), Expect = 0.010
Identities = 40/147 (27%), Positives = 70/147 (47%), Gaps = 27/147 (18%)
Query: 151 DFESHITSYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRK 210
D ES +++ + ++E AE DSE +ED ++ G S++ S E+RK
Sbjct: 81 DSESEELHRQKDSDSESEERAEPPASDSE---NEDVNQHG----------SDSESEETRK 127
Query: 211 FLKKMDDEDED--SEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKK 268
L D E+E+ + + D E+ D G + SDSE EE L+K+P +D + +
Sbjct: 128 -LPGSDSENEELLNGHASDSENEDVGKHPA-SDSEIEE----------LQKSPASDSETE 175
Query: 269 AAEKKREDKAKKKHDRKSKRLDEEEED 295
A K + ++ + + + D E E+
Sbjct: 176 DALKPQISDSESEEPPRHQASDSENEE 202
Score = 38.9 bits (89), Expect = 0.022
Identities = 51/239 (21%), Positives = 100/239 (41%), Gaps = 27/239 (11%)
Query: 142 RQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSA------AT 195
R+K + + E H + E + + EK + + EDE+ SA +
Sbjct: 357 RKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSD 416
Query: 196 FLKKKSEAPSGESRKFLKKM--DDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALA 253
S+A S +S K K + D E+E ++ D ++ + SDS+S EE + +A
Sbjct: 417 ADDSDSDAVSDKSGKREKTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNEE--ENLIA 474
Query: 254 SRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDN---EGGEWERVRGGVPL 310
F + +E+++ +ED ++K + + K ++ + D+ G + + +
Sbjct: 475 DIFGESG--DEEEEEFTGFNQEDLEEEKGETQVKEAEDSDSDDNIKRGKHMDFLSDFEMM 532
Query: 311 VKEKPKMFAK-------GTEITHA-----VVIKKLNEILQARGKKGTDRAAQIELLQLL 357
++ K M K GT I+ A +I K+NE + + + ++ L LL
Sbjct: 533 LQRKKSMSGKRRRNRDGGTFISDADDVVSAMIVKMNEAAEEDRQLNNQKKPALKKLTLL 591
Score = 35.4 bits (80), Expect = 0.24
Identities = 42/208 (20%), Positives = 87/208 (41%), Gaps = 21/208 (10%)
Query: 99 KEGVPRFYIRILADLEDYLNELWEDKEGKKKMNKNNAKALSTLRQK---IRKYNRDFESH 155
++G+P+ + ++ ++ LN D E ++ + ++ + S R + N D H
Sbjct: 57 EDGLPKGHHVTDSENDEPLNLNASDSESEELHRQKDSDSESEERAEPPASDSENEDVNQH 116
Query: 156 ITSYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESR-KFLKK 214
+ + + +NEE G + + E+ED + P+ +S + L+K
Sbjct: 117 GSDSESEETRKLPGSDSENEELLNGHASDSENED----------VGKHPASDSEIEELQK 166
Query: 215 MDDEDEDSEDSEDDEDWDTGSTS----SDSDSEEEEGKQTALA---SRFLKKAPTTDEDK 267
D ++ED+ + D+ S SDSE EE + ++ S L K +D +
Sbjct: 167 SPASDSETEDALKPQISDSESEEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSES 226
Query: 268 KAAEKKREDKAKKKHDRKSKRLDEEEED 295
+ + + ++ + K + D E ED
Sbjct: 227 EEPPRHQASDSENEELPKPRISDSESED 254
Score = 35.0 bits (79), Expect = 0.32
Identities = 41/191 (21%), Positives = 82/191 (42%), Gaps = 24/191 (12%)
Query: 98 DKEGVPRFYIRILADLEDYLNELWEDKEGKKK---MNKNNAKALSTLRQKIRKYNRDFES 154
D+E R+++D +D ++ DK GK++ + + +A L K + F S
Sbjct: 402 DEEKASAKKSRVVSDADDSDSDAVSDKSGKREKTIASDSEEEAGKELSDKKNEEKDLFGS 461
Query: 155 HITSYKQNPEQSAD---EDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKF 211
S + AD E ++ EE+ G + ED +E+ T +K+ ++ S ++ K
Sbjct: 462 DSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEE--KGETQVKEAEDSDSDDNIKR 519
Query: 212 LKKMDD--------EDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTT 263
K MD + + S + + D G+ SD+D +++ +K
Sbjct: 520 GKHMDFLSDFEMMLQRKKSMSGKRRRNRDGGTFISDADD--------VVSAMIVKMNEAA 571
Query: 264 DEDKKAAEKKR 274
+ED++ +K+
Sbjct: 572 EEDRQLNNQKK 582
Score = 34.3 bits (77), Expect = 0.54
Identities = 34/144 (23%), Positives = 62/144 (43%), Gaps = 9/144 (6%)
Query: 153 ESHITSYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFL 212
+S S Q+ + A ++ + S+G D +E G + +++ SE + + L
Sbjct: 2 DSEYYSGDQSDDGGATPVQDERDSGSDGEDDVNEQHSGSDTGS-VERHSENETSDREDGL 60
Query: 213 KKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEE-EEGKQTALASRFLKKAPTTDEDKKAAE 271
K DSE+DE + + SDS+SEE K + S + P +D + +
Sbjct: 61 PK----GHHVTDSENDEPLNLNA--SDSESEELHRQKDSDSESEERAEPPASDSENEDVN 114
Query: 272 KKREDKAKKKHDRKSKRLDEEEED 295
+ D ++ + RK D E E+
Sbjct: 115 QHGSD-SESEETRKLPGSDSENEE 137
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 57.4 bits (137), Expect = 6e-08
Identities = 59/252 (23%), Positives = 111/252 (44%), Gaps = 42/252 (16%)
Query: 128 KKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDEDED 187
+ ++NN+K S K KY + + E +DA+K+ + + + +D+
Sbjct: 266 RNYSQNNSKNYSL---KYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDK 322
Query: 188 EDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEG 247
+ V T + ++A SG+S+ ++ D + + + +DD+ DT +D+E +
Sbjct: 323 KKDVKKDT---ESTDAESGDSKD--ERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDA 377
Query: 248 KQTALASRFLKKAPTTDEDKKAAEK--------------------KREDKAKKKHDRKSK 287
K SR LKKA D+ KK A+K K++ K K ++KS
Sbjct: 378 KDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSV 437
Query: 288 RLDEE--------EEDNEGGEWERVRGGVPLVKEKPKMFAK----GTEITHAVVIKKLNE 335
+ DEE + D++ G+ + +G K+ K AK TE+ + +KK +
Sbjct: 438 KNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKK--D 495
Query: 336 ILQARGKKGTDR 347
++ KKG+ +
Sbjct: 496 KKHSKEKKGSKK 507
Score = 53.9 bits (128), Expect = 7e-07
Identities = 81/319 (25%), Positives = 128/319 (40%), Gaps = 49/319 (15%)
Query: 10 DSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRS-------AKDKRFEELTN 62
D+ES + SG+ + K+ L + ++DTK+ S AKD R + N
Sbjct: 329 DTESTDAESGDSKDERK-DTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDAR-NDSRN 386
Query: 63 LIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNELWE 122
L + +N K +D K + + K +K+ D +D
Sbjct: 387 LKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKK-----------DKKD------- 428
Query: 123 DKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSS 182
K KK KN+ ++ + + + K + + +DA+KN E +E S
Sbjct: 429 SKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMES 488
Query: 183 DEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSS---- 238
D + +D KK S+ G S+K +KK +D +S D+E DE TG +S
Sbjct: 489 DLELKKD--------KKHSKEKKG-SKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIK 539
Query: 239 DSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNEG 298
SD+E EE A K + D +A K E K+ R S + + NE
Sbjct: 540 GSDTESEESLYKPGA-----KKKIDESDGTSANSKMEGLESKRGFRMSSK---KTTFNEK 591
Query: 299 GEWERVRGGVPLVKEKPKM 317
GE + G VP +EKP +
Sbjct: 592 GE-KASTGRVPPSREKPPL 609
Score = 36.6 bits (83), Expect = 0.11
Identities = 36/179 (20%), Positives = 73/179 (40%), Gaps = 19/179 (10%)
Query: 123 DKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSS 182
+ + K ++KN ++ + +K N +F + K++ ++S + +E SE S
Sbjct: 184 ESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSL 243
Query: 183 DED-------EDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGS 235
+ D D++ ++ +L+ S+ S K +D +
Sbjct: 244 NVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKK------------N 291
Query: 236 TSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEE 294
SD+E E+ K S+ +KK D+ KK +K E + D K +R D +++
Sbjct: 292 AKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKD 350
>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member B [Homo sapiens]
Length = 251
Score = 57.0 bits (136), Expect = 8e-08
Identities = 43/147 (29%), Positives = 66/147 (44%), Gaps = 43/147 (29%)
Query: 154 SHITSYKQNPEQSADEDAE-----KNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGES 208
+++ Y + +++ D DAE + EED EG +EDED++ GE
Sbjct: 143 TYLDGYDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDE---------------DGEE 187
Query: 209 RKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKK 268
+F D+ED++ ED E DED D SEEEE + +ED+
Sbjct: 188 EEF----DEEDDEDEDVEGDED-------DDEVSEEEE------------EFGLDEEDED 224
Query: 269 AAEKKREDKAKKKHDRKSKRLDEEEED 295
E + E++ K RK + DE E+D
Sbjct: 225 EDEDEEEEEGGKGEKRKRETDDEGEDD 251
Score = 43.5 bits (101), Expect = 9e-04
Identities = 32/111 (28%), Positives = 55/111 (49%), Gaps = 26/111 (23%)
Query: 198 KKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFL 257
++ EAP ++ + +D+E+ED E+ ED+ED D D D EEEE +
Sbjct: 150 REDQEAPDSDAE--VDGVDEEEED-EEGEDEEDED------DEDGEEEEFDE-------- 192
Query: 258 KKAPTTDEDKKAAEKKREDKAKKKH-----DRKSKRLDEEEEDNEGGEWER 303
DED+ + +D+ ++ D + + DE+EE+ EGG+ E+
Sbjct: 193 ----EDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEK 239
Score = 32.0 bits (71), Expect = 2.7
Identities = 25/107 (23%), Positives = 50/107 (46%), Gaps = 19/107 (17%)
Query: 115 DYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKN 174
D ++E ED+EG+ + ++++ ++ D E ++ ++ ++E+ E
Sbjct: 163 DGVDEEEEDEEGEDEEDEDDEDG-----EEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFG 217
Query: 175 EEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDED 221
++ + DEDE+E+ E GE RK ++ DDE ED
Sbjct: 218 LDEEDEDEDEDEEEE------------EGGKGEKRK--RETDDEGED 250
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 56.6 bits (135), Expect = 1e-07
Identities = 49/191 (25%), Positives = 88/191 (46%), Gaps = 26/191 (13%)
Query: 121 WEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEG 180
W+ E + ++ K+ K R+ K R E+ +E+++ + SE
Sbjct: 2123 WDFSEKRSELTKDEKKLARKQRKLANKMRRMINKE--------EKMTEEESKLARKHSEV 2174
Query: 181 SSDEDEDEDGVS---AATFLK----KKSEAPSGES--RKFLKKMDDEDEDSEDSED---- 227
D DE+E G+ FLK K+ EA G+ KF ++D+ + + SE+
Sbjct: 2175 ILD-DEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESL 2233
Query: 228 -DEDWDTGSTSSDSDSE---EEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHD 283
DE S SS+ + E EEE ++ + ++ + ++K EK+ E+K KKK +
Sbjct: 2234 LDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKE 2293
Query: 284 RKSKRLDEEEE 294
+K + + E+EE
Sbjct: 2294 KKKEEVQEKEE 2304
Score = 38.1 bits (87), Expect = 0.038
Identities = 43/213 (20%), Positives = 89/213 (41%), Gaps = 16/213 (7%)
Query: 50 RSAKDKRFEELTNLIRTIRNAMK--IRDVTKCLEEFELLGKAYGKA-------KSIVDKE 100
RS K ++L R + N M+ I K EE L + + + I ++E
Sbjct: 2129 RSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEE 2188
Query: 101 GVP----RFYIRILADLEDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKY---NRDFE 153
+P R+ R A D E + + + + ++ ++ + +L ++ K + + E
Sbjct: 2189 VIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEE 2248
Query: 154 SHITSYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLK 213
++ E+ E+ E+ +E+ EG + E E+ +KK E + F +
Sbjct: 2249 EEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEE 2308
Query: 214 KMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEE 246
K + E+ +S DE+ + S S + + + E+
Sbjct: 2309 KEEIMSEEETESLSDEEEEEESCSLEEEVDREK 2341
Score = 30.8 bits (68), Expect = 6.0
Identities = 45/260 (17%), Positives = 105/260 (40%), Gaps = 34/260 (13%)
Query: 124 KEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAE-------KNEE 176
K+G+K + K + + +++++ K RD + E+ ++ + + +
Sbjct: 1401 KQGRKAVQKE--RKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQ 1458
Query: 177 DSEGSSDEDEDEDGVSAATFLKKKSE------------APSGESRKFLKKMDDEDEDSED 224
D + + DE + G + ++ K E +GE ++M ED+ +
Sbjct: 1459 DWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKW 1518
Query: 225 SEDDEDWDTGSTSSDSDSEEEEGKQTALASRFL-----KKAPTTDEDKKAAEK------- 272
E + W+ +S + + ++ ++ L K+ T+E + E+
Sbjct: 1519 EEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIH 1578
Query: 273 KREDKAKKKHDRKSKRLDEEEEDNEGGEWERVRGGVPLVKEKPKMFAKGTEITHAV-VIK 331
++ +A+KK ++ ++L +EEE E + + L + K+ E+ A
Sbjct: 1579 RKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFA 1638
Query: 332 KLNEILQARGKKGTDRAAQI 351
+ E L RG+K + A ++
Sbjct: 1639 QKEETLAQRGEKLSQEAEKL 1658
>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
Length = 1390
Score = 56.2 bits (134), Expect = 1e-07
Identities = 54/249 (21%), Positives = 106/249 (42%), Gaps = 40/249 (16%)
Query: 38 LSEDEEDTKRVVRSAKDKRFEE-LTNLIRTIRNAMKIRDVTKCLEEF-----ELLGKAYG 91
L+ T+++ R DK+ EE + + + +++ R++ + E ++ +
Sbjct: 99 LANGRHFTRQLARQQADKKKEEHREDKVIPVTRSLRARNIVQSTEHLHEDNGDVEVRRSC 158
Query: 92 KAKSIVDKEGVPRFYIRILADLEDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRD 151
+ +S + +++ + + + + +D KKM + + L L +N
Sbjct: 159 RIRSRYSGVNQSMLFDKLITNTAEAVLQKMDDM---KKMRRQRMRELEDLGV----FNET 211
Query: 152 FESHITSY---KQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGES 208
ES++ Y KQ Q DE+ N+E S SS+E ED++ GE
Sbjct: 212 EESNLNMYTRGKQKDIQRTDEETTDNQEGSVESSEEGEDQE------------HEDDGED 259
Query: 209 RKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKK 268
DDED+D +D +DD+D D + D +EE+G++ +L++ T +
Sbjct: 260 E------DDEDDDDDDDDDDDDDD------EDDEDEEDGEEENQKRYYLRQRKATVYYQA 307
Query: 269 AAEKKREDK 277
EK R +
Sbjct: 308 PLEKPRHQR 316
>gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo
sapiens]
Length = 1094
Score = 55.8 bits (133), Expect = 2e-07
Identities = 39/153 (25%), Positives = 66/153 (43%), Gaps = 10/153 (6%)
Query: 128 KKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDEDED 187
K +N+AK K + + E S + +S E E+ E EG S+ED
Sbjct: 665 KAKQENSAK-------KFYSESEEEEDSSDSSSDSESESGSESGEQGESGEEGDSNEDSS 717
Query: 188 EDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEG 247
ED S +S SG K K + + + DSED E + S +SDS ++E
Sbjct: 718 EDSSSEQD---SESGRESGLENKRTAKRNSKAKGKSDSEDGEKENEKSKTSDSSNDESSS 774
Query: 248 KQTALASRFLKKAPTTDEDKKAAEKKREDKAKK 280
+ + + + P ++ + + K++E K K+
Sbjct: 775 IEDSSSDSESESEPESESESRRVTKEKEKKTKQ 807
Score = 44.7 bits (104), Expect = 4e-04
Identities = 33/135 (24%), Positives = 62/135 (45%), Gaps = 8/135 (5%)
Query: 182 SDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSD 241
S+ +E+ED +++ + +S + SGE + ++ D ++ SEDS ++D ++G S
Sbjct: 677 SESEEEEDSSDSSSDSESESGSESGEQGESGEEGDSNEDSSEDSSSEQDSESGRESG--- 733
Query: 242 SEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNEGGEW 301
E K+TA + K +++ +K EK + + +D S D + E
Sbjct: 734 ---LENKRTAKRNSKAKGKSDSEDGEKENEKSK--TSDSSNDESSSIEDSSSDSESESEP 788
Query: 302 ERVRGGVPLVKEKPK 316
E + KEK K
Sbjct: 789 ESESESRRVTKEKEK 803
Score = 38.9 bits (89), Expect = 0.022
Identities = 29/104 (27%), Positives = 48/104 (46%), Gaps = 6/104 (5%)
Query: 200 KSEAPSGESRK--FLKKMDDEDEDSEDSED---DEDWDTGSTSSDSDSEEEEGKQTALAS 254
K P+G++++ KK E E+ EDS D D + ++GS S + EEG +S
Sbjct: 658 KEWTPAGKAKQENSAKKFYSESEEEEDSSDSSSDSESESGSESGEQGESGEEGDSNEDSS 717
Query: 255 RFLKKAPTTDEDKKAA-EKKREDKAKKKHDRKSKRLDEEEEDNE 297
++ +++ E KR K K KS D E+E+ +
Sbjct: 718 EDSSSEQDSESGRESGLENKRTAKRNSKAKGKSDSEDGEKENEK 761
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 55.8 bits (133), Expect = 2e-07
Identities = 33/126 (26%), Positives = 62/126 (49%), Gaps = 4/126 (3%)
Query: 122 EDKEGKKKMNKNNAKALSTLRQKIRKYNRD-FESHITSYKQNPEQSADEDAEKNEEDSEG 180
+D+ K+ N K+++ LR K +R +S S + + E DED ++ EED E
Sbjct: 603 QDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDEN 662
Query: 181 SSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDS 240
D EDG ++ + E+ + + DD+++D ED +++ + + S+SS
Sbjct: 663 G---DSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSG 719
Query: 241 DSEEEE 246
DS + +
Sbjct: 720 DSSDSD 725
Score = 44.3 bits (103), Expect = 5e-04
Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 12/90 (13%)
Query: 208 SRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDK 267
SR L+ + +ED E+ EDDED D ++ E+G ++ +S + DE +
Sbjct: 630 SRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESS-------SEDESE 682
Query: 268 KAAEKKREDKAKKKHDRKSKRLDEEEEDNE 297
E + +D+ D D+E+EDNE
Sbjct: 683 DGDENEEDDE-----DEDDDEDDDEDEDNE 707
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 55.8 bits (133), Expect = 2e-07
Identities = 33/126 (26%), Positives = 62/126 (49%), Gaps = 4/126 (3%)
Query: 122 EDKEGKKKMNKNNAKALSTLRQKIRKYNRD-FESHITSYKQNPEQSADEDAEKNEEDSEG 180
+D+ K+ N K+++ LR K +R +S S + + E DED ++ EED E
Sbjct: 603 QDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDEN 662
Query: 181 SSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDS 240
D EDG ++ + E+ + + DD+++D ED +++ + + S+SS
Sbjct: 663 G---DSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSG 719
Query: 241 DSEEEE 246
DS + +
Sbjct: 720 DSSDSD 725
Score = 44.3 bits (103), Expect = 5e-04
Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 12/90 (13%)
Query: 208 SRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDK 267
SR L+ + +ED E+ EDDED D ++ E+G ++ +S + DE +
Sbjct: 630 SRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESS-------SEDESE 682
Query: 268 KAAEKKREDKAKKKHDRKSKRLDEEEEDNE 297
E + +D+ D D+E+EDNE
Sbjct: 683 DGDENEEDDE-----DEDDDEDDDEDEDNE 707
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 55.8 bits (133), Expect = 2e-07
Identities = 33/126 (26%), Positives = 62/126 (49%), Gaps = 4/126 (3%)
Query: 122 EDKEGKKKMNKNNAKALSTLRQKIRKYNRD-FESHITSYKQNPEQSADEDAEKNEEDSEG 180
+D+ K+ N K+++ LR K +R +S S + + E DED ++ EED E
Sbjct: 640 QDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDEN 699
Query: 181 SSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDS 240
D EDG ++ + E+ + + DD+++D ED +++ + + S+SS
Sbjct: 700 G---DSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSG 756
Query: 241 DSEEEE 246
DS + +
Sbjct: 757 DSSDSD 762
Score = 44.3 bits (103), Expect = 5e-04
Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 12/90 (13%)
Query: 208 SRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDK 267
SR L+ + +ED E+ EDDED D ++ E+G ++ +S + DE +
Sbjct: 667 SRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESS-------SEDESE 719
Query: 268 KAAEKKREDKAKKKHDRKSKRLDEEEEDNE 297
E + +D+ D D+E+EDNE
Sbjct: 720 DGDENEEDDE-----DEDDDEDDDEDEDNE 744
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 54.7 bits (130), Expect = 4e-07
Identities = 40/149 (26%), Positives = 71/149 (47%), Gaps = 13/149 (8%)
Query: 160 KQNPEQSADEDAEKNEEDSEGSSDED--EDEDGVSAATFLKKKSEAPSGESRKFLKKMDD 217
K++ E +E E +ED + +ED ED++G K+K + GE K +D
Sbjct: 131 KEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGK--GNGED 188
Query: 218 EDEDSEDSEDDED-WDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKRED 276
E ED +++ED +TG + D +E+ K+ K ED+K E +ED
Sbjct: 189 GKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEG-------KDVKVKEDEKEREDGKED 241
Query: 277 KAKKKHDRKSKRLDEEEEDNEGGEWERVR 305
+ + + ++ D +EE+ EG E + ++
Sbjct: 242 EGGNEEEAGKEKEDLKEEE-EGKEEDEIK 269
Score = 49.7 bits (117), Expect = 1e-05
Identities = 36/134 (26%), Positives = 64/134 (47%), Gaps = 14/134 (10%)
Query: 173 KNEEDSEGSSDEDEDED-GVSAATFLKKKSEAPSGESRKFLKKMDD--EDEDSEDSEDDE 229
KNEE+ + +ED++E+ G + +K E E + +K +D E ED + ED +
Sbjct: 124 KNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGK 183
Query: 230 -DWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKR 288
+ + G + + EEE+ K+T ++ K+ +KK K K D K +
Sbjct: 184 GNGEDGKEKGEDEKEEEDRKETG-------DGKENEDGKEKGDKKEGKDVKVKEDEKER- 235
Query: 289 LDEEEEDNEGGEWE 302
E+ +++EGG E
Sbjct: 236 --EDGKEDEGGNEE 247
Score = 44.7 bits (104), Expect = 4e-04
Identities = 44/192 (22%), Positives = 82/192 (42%), Gaps = 26/192 (13%)
Query: 160 KQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDED 219
++N E + ++ EK E + +E+ED+ K+ E E + K D ++
Sbjct: 102 EENIEDATEKGGEKKEAVAAEVKNEEEDQ----------KEDEEDQNEEKGEAGKEDKDE 151
Query: 220 EDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAE-------- 271
+ ED ++D++ G+ + E+E+GK+ + ED+K E
Sbjct: 152 KGEEDGKEDKN---GNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDG 208
Query: 272 KKREDKAKKKHDRKSKRLDEEEEDNEGGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIK 331
K+ ED +K ++ K + +E++ E + + GG K K K E K
Sbjct: 209 KENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEG-----K 263
Query: 332 KLNEILQARGKK 343
+ +EI + GKK
Sbjct: 264 EEDEIKEDDGKK 275
Score = 38.9 bits (89), Expect = 0.022
Identities = 32/136 (23%), Positives = 56/136 (41%), Gaps = 6/136 (4%)
Query: 164 EQSADEDAEKNEEDSEGSSDE-DEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDS 222
E +ED +N ++ E E E + + G +K + ++E+
Sbjct: 69 EAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEE 128
Query: 223 EDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAE--KKREDKAKK 280
+ ED+ED + + + ++E+G++ K ED K E KK ED
Sbjct: 129 DQKEDEEDQNEEKGEAGKEDKDEKGEEDGKED---KNGNEKGEDAKEKEDGKKGEDGKGN 185
Query: 281 KHDRKSKRLDEEEEDN 296
D K K DE+EE++
Sbjct: 186 GEDGKEKGEDEKEEED 201
Score = 38.5 bits (88), Expect = 0.029
Identities = 39/182 (21%), Positives = 84/182 (46%), Gaps = 16/182 (8%)
Query: 134 NAKALSTLRQKI---RKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDED-EDED 189
+A+A++ +Q+ YN + ++ + P S E E EE+ E ++++ E ++
Sbjct: 59 SAQAVAETKQEAVVEEDYNENAKNGEAKITEAPA-SEKEIVEVKEENIEDATEKGGEKKE 117
Query: 190 GVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWD-TGSTSSDSDSEEEEGK 248
V+A +++ + E + K +++ E E+D D G+ + E+E+GK
Sbjct: 118 AVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGK 177
Query: 249 QTALASRFLKKAPTTDEDKKAAEKKRE-------DKAKKKHDR---KSKRLDEEEEDNEG 298
+ + ED+K E ++E + K+K D+ K ++ E+E++ E
Sbjct: 178 KGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKERED 237
Query: 299 GE 300
G+
Sbjct: 238 GK 239
Score = 35.8 bits (81), Expect = 0.19
Identities = 24/107 (22%), Positives = 49/107 (45%), Gaps = 13/107 (12%)
Query: 205 SGESRKFLKKMDDEDEDSEDSED-----------DEDWDTGSTSSDSDSEEEEGKQTALA 253
+ SRK K D +E+ + S +ED++ + + ++ E + +
Sbjct: 39 TSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIV 98
Query: 254 SRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNEGGE 300
+K+ D +K EKK A+ K++ + ++ DEE+++ E GE
Sbjct: 99 E--VKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGE 143
Score = 30.8 bits (68), Expect = 6.0
Identities = 35/180 (19%), Positives = 79/180 (43%), Gaps = 27/180 (15%)
Query: 122 EDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGS 181
E K +++ ++ K +R ++ ++N + SA AE +E
Sbjct: 15 EPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQE---AV 71
Query: 182 SDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSD 241
+ED +E+ + K +EAP+ E + ++ ++E+ ED+ + + +++
Sbjct: 72 VEEDYNENAKNGEA---KITEAPASEK----EIVEVKEENIEDATEKGGEKKEAVAAEVK 124
Query: 242 SEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEED-NEGGE 300
+EEE+ K ED++ +++ + K+ D K + +E+++ NE GE
Sbjct: 125 NEEEDQK----------------EDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGE 168
Score = 30.4 bits (67), Expect = 7.9
Identities = 17/69 (24%), Positives = 35/69 (50%), Gaps = 5/69 (7%)
Query: 122 EDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGS 181
E+++GK+K +K K + K+++ ++ E N E++ E + EE+
Sbjct: 210 ENEDGKEKGDKKEGKDV-----KVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKE 264
Query: 182 SDEDEDEDG 190
DE +++DG
Sbjct: 265 EDEIKEDDG 273
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 54.7 bits (130), Expect = 4e-07
Identities = 65/265 (24%), Positives = 120/265 (45%), Gaps = 31/265 (11%)
Query: 110 LADLEDYLNELWEDKEGKKKMNKNNAKAL---------STLRQKIRKYNRDFESHITSYK 160
+ ++ED +L E + + + KN +A ST I +++ I K
Sbjct: 483 IKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDLAK 542
Query: 161 QNPEQSADEDAEKNE-----EDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKM 215
++ E+ ++ K + ED+ + E ++E GVS ++ +E ES++ +
Sbjct: 543 KDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSE----RENNELEVEESQE-VSDH 597
Query: 216 DDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALAS---RFLKKAPTTDEDKKAAEK 272
+DE+E+ E+ EDD D S SDS+S+E+ Q LA+ K DE + + +
Sbjct: 598 EDEEEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENS--Q 655
Query: 273 KREDKAKKKHDRKSKRLDEEEEDNEGGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKK 332
KR KK+++ K L + D + E ++V + V+ + AK + ++
Sbjct: 656 KRLQTLKKQYEEKLMMLQHKIRDTQ-LERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQA 714
Query: 333 LNEILQARGKKGTDRAAQIELLQLL 357
+N+ LQ +AAQ E +LL
Sbjct: 715 MNKELQRL------QAAQKEHARLL 733
>gi|195976782 Paf1/RNA polymerase II complex component [Homo
sapiens]
Length = 710
Score = 54.3 bits (129), Expect = 5e-07
Identities = 62/241 (25%), Positives = 91/241 (37%), Gaps = 59/241 (24%)
Query: 6 TTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIR 65
++ S S+S+SS EE YG+ L DEED R+ + + +R +EL N I
Sbjct: 162 SSSSSSDSDSSSEDEEF-----HDGYGED---LMGDEEDRARLEQMTEKEREQELFNRIE 213
Query: 66 TIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNELWEDKE 125
R+V K FE+ K K E KE
Sbjct: 214 K-------REVLK--RRFEIKKKLKTAKKK--------------------------EKKE 238
Query: 126 GKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDED 185
KKK + K +K + ES +TS+ + DE +K + E E
Sbjct: 239 KKKKQEEEQEK---------KKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAER 289
Query: 186 EDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEE 245
E +A KK + K + D++E+ ED + E D S +S SD EEE
Sbjct: 290 EKRKNRTAELLAKK-------QPLKTSEVYSDDEEEEEDDKSSEKSDRSSRTSSSDEEEE 342
Query: 246 E 246
+
Sbjct: 343 K 343
Score = 43.5 bits (101), Expect = 9e-04
Identities = 46/236 (19%), Positives = 89/236 (37%), Gaps = 63/236 (26%)
Query: 125 EGKKKMNKNNAKALSTLRQKIRKY------NRDFESHITSYKQNPEQSADEDAEKNEEDS 178
+ KKK + T++++ K ++D + ++ ++ +D ++ + DS
Sbjct: 110 KNKKKGKARKIEKKGTMKKQANKTASSGSSDKDSSAESSAPEEGEVSDSDSNSSSSSSDS 169
Query: 179 EGSSDEDEDEDGVSAATF------------------------------------LKKKSE 202
+ SS+++E DG +KKK +
Sbjct: 170 DSSSEDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKRRFEIKKKLK 229
Query: 203 APSGESRKFLKKMDDEDEDSED-----------------SEDDEDWDTGSTSSDSDSEEE 245
+ +K KK +E+++ + S+ DE D S + + E
Sbjct: 230 TAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAER 289
Query: 246 EGKQTALASRFLKKAP--TTDEDKKAAEKKREDKAKKKHDRKSK--RLDEEEEDNE 297
E ++ A KK P T++ E++ +DK+ +K DR S+ DEEEE E
Sbjct: 290 EKRKNRTAELLAKKQPLKTSEVYSDDEEEEEDDKSSEKSDRSSRTSSSDEEEEKEE 345
Score = 41.6 bits (96), Expect = 0.003
Identities = 38/162 (23%), Positives = 65/162 (40%), Gaps = 28/162 (17%)
Query: 164 EQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKK-------KSEAPSGESRKFLKKMD 216
+ +A D+E ++ D E + ++++ A KK A SG S K
Sbjct: 88 QPAASSDSETSDSDDEWTFGSNKNKKKGKARKIEKKGTMKKQANKTASSGSSDKDSSAES 147
Query: 217 DEDEDSEDSEDDEDWDTGSTSSDSDSEEEE----------GKQTALA-----------SR 255
E+ E S+ D + + S+ SDS SE+EE G + A
Sbjct: 148 SAPEEGEVSDSDSNSSSSSSDSDSSSEDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQE 207
Query: 256 FLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNE 297
+ + K+ E K++ K KK ++K K+ +EEE +
Sbjct: 208 LFNRIEKREVLKRRFEIKKKLKTAKKKEKKEKKKKQEEEQEK 249
>gi|31317305 M-phase phosphoprotein 10 [Homo sapiens]
Length = 681
Score = 53.9 bits (128), Expect = 7e-07
Identities = 47/191 (24%), Positives = 88/191 (46%), Gaps = 18/191 (9%)
Query: 111 ADLEDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADED 170
+DL+ +++L + + + K + + S + K K + + E+++ + ++ E+ D D
Sbjct: 171 SDLDFDISKLEQQSKVQNK-GQGKPREKSIVDDKFFKLS-EMEAYLENIEKEEERKDDND 228
Query: 171 AEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMD--DEDEDSEDSEDD 228
E+ + D D DEDE G+ + LK SG+S + LK D D E ED +
Sbjct: 229 EEEEDIDFFEDIDSDEDEGGLFGSKKLK------SGKSSRNLKYKDFFDPVESDEDITNV 282
Query: 229 EDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKR 288
D + S D + EEE ++ +++ TDED E + + K+ R +
Sbjct: 283 HDDELDSNKEDDEIAEEEAEELSISE--------TDEDDDLQENEDNKQHKESLKRVTFA 334
Query: 289 LDEEEEDNEGG 299
L ++ E + G
Sbjct: 335 LPDDAETEDTG 345
Score = 36.2 bits (82), Expect = 0.14
Identities = 51/241 (21%), Positives = 100/241 (41%), Gaps = 35/241 (14%)
Query: 74 RDVTKCLEEFELLGKAYGKAKSIVD-KEGVPRFYIRILADLEDY---------------- 116
R + +CL E +GKA G+ + + +EG+ + + L D+
Sbjct: 9 RTLERCLTE---VGKATGRPECFLTIQEGLASKFTSLTKVLYDFNKILENGRIHGSPLQK 65
Query: 117 -LNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNE 175
+ E ++D++ +++ N L + + + D + I+ ++ EQ +ED + E
Sbjct: 66 LVIENFDDEQIWQQLELQNEPILQYFQNAVSETINDED--ISLLPESEEQEREEDGSEIE 123
Query: 176 EDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMD-DEDEDSEDSEDDEDWDTG 234
D + ++ E+E+ + E S+ L+K DEDS D D+D
Sbjct: 124 ADDKEDLEDLEEEEVSDMGNDDPEMGERAENSSKSDLRKSPVFSDEDS-----DLDFDI- 177
Query: 235 STSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEE 294
S E++ Q + +K+ D+ K +E + + +K + + DEEEE
Sbjct: 178 -----SKLEQQSKVQNKGQGKPREKSIVDDKFFKLSEMEAYLENIEKEEERKDDNDEEEE 232
Query: 295 D 295
D
Sbjct: 233 D 233
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 53.9 bits (128), Expect = 7e-07
Identities = 57/246 (23%), Positives = 104/246 (42%), Gaps = 42/246 (17%)
Query: 99 KEGVPRFYIRILADLEDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITS 158
K P+ + +D +D N+L K+ K K K+N K + + S I S
Sbjct: 125 KTAKPKVEMYSGSDDDDDFNKL--PKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINS 182
Query: 159 YKQNPEQSAD-----EDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLK 213
++ ++S + + +KN+++ G + E +ED A+ +K ++ + + + K
Sbjct: 183 SGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDD-DASFKIKTVAQKKAEKKERERK 241
Query: 214 KMDDEDEDSEDSEDDEDWDTGSTSSDSDSE-----EEEGKQTAL--------ASRFLKKA 260
K D+E ++ E+ +TG E EEE ++ + AS +
Sbjct: 242 KRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAET 301
Query: 261 PTTDEDKKAAEKKREDKAKKKHDRKSK---------------------RLDEEEEDNEGG 299
PT ED +KK++DK KKK +++ K +L EEEE +
Sbjct: 302 PTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKRE 361
Query: 300 EWERVR 305
E ER++
Sbjct: 362 EEERIK 367
Score = 48.5 bits (114), Expect = 3e-05
Identities = 61/280 (21%), Positives = 121/280 (43%), Gaps = 38/280 (13%)
Query: 40 EDEEDTKRVVRSAKDKRFEELTNLIRTIRNAMKIRDVTKCLE-EFELLGKAYGKAKS--- 95
E+EE KR+ ++ EE + R K ++ + L+ E +LL K+ +A++
Sbjct: 361 EEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAE 420
Query: 96 ----IVDKEGVPRFYIRILADLEDYLNE---LWEDKEGKKKMNKNNAKALSTLRQKIRKY 148
++ +GV +D L + ++EDK+ KK + +K +S +
Sbjct: 421 ATLKLLQAQGVE-------VPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAV 473
Query: 149 NRDFESHITSYKQNP---EQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPS 205
E + ++ P E +ED E D + DE+ + V + E P
Sbjct: 474 EV-MEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPE 532
Query: 206 GESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTD- 264
E + ++ +DE+ + E+ E+ E S S+ D E+E+ + + L K P+ +
Sbjct: 533 EEEEEEEEEEEDEESEEEEEEEGE-----SEGSEGDEEDEKVSDEKDSGKTLDKKPSKEM 587
Query: 265 --------EDKKAAEKKREDKAKKKHDRKSKRLDEEEEDN 296
+D + E++ DKAK++ ++ +RL+ + N
Sbjct: 588 SSDSEYDSDDDRTKEERAYDKAKRRIEK--RRLEHSKNVN 625
Score = 44.3 bits (103), Expect = 5e-04
Identities = 48/200 (24%), Positives = 96/200 (48%), Gaps = 24/200 (12%)
Query: 124 KEGK---KKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEG 180
KEGK K + A+A +TL+ ++ + S + K+ P ED ++ + +
Sbjct: 403 KEGKLLTKSQREARARAEATLKL-LQAQGVEVPSKDSLPKKRPIY---EDKKRKKIPQQL 458
Query: 181 SSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDS 240
S E + + AA + ++ E+ ++ +E+ED+ED+ D DW+ + +SD
Sbjct: 459 ESKEVSESMELCAAVEVMEQGVPEKEETPPPVEP--EEEEDTEDAGLD-DWE--AMASDE 513
Query: 241 DSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNEGGE 300
++E+ EG + + E K+ E++ E++ +++ D +S+ +EEE ++EG E
Sbjct: 514 ETEKVEGNKVHI------------EVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSE 561
Query: 301 WERVRGGVPLVKEKPKMFAK 320
+ V K+ K K
Sbjct: 562 GDEEDEKVSDEKDSGKTLDK 581
Score = 43.9 bits (102), Expect = 7e-04
Identities = 38/222 (17%), Positives = 101/222 (45%), Gaps = 10/222 (4%)
Query: 122 EDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGS 181
ED + K+ K A+ + +++ RK + ++ + K+ E + + +++S+
Sbjct: 217 EDDDASFKI-KTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRK 275
Query: 182 SDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSD 241
+E+ + V+ T + P+ E + ++D + + + D+ G + +
Sbjct: 276 FEEETVKSKVTVDTGV-----IPASEEKAETPTAAEDDNEGDKKKKDKKKKKGE-KEEKE 329
Query: 242 SEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEE--EEDNEGG 299
E+++G A + E+++ +++ E++ K+ + ++KR +EE E++
Sbjct: 330 KEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRER 389
Query: 300 EWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARG 341
+ ++ + +K++ K+ K A L ++LQA+G
Sbjct: 390 KKQKEKERKERLKKEGKLLTKSQREARARAEATL-KLLQAQG 430
Score = 38.5 bits (88), Expect = 0.029
Identities = 51/192 (26%), Positives = 76/192 (39%), Gaps = 26/192 (13%)
Query: 126 GKKKMNKNNAKA-----LSTLRQKIR-----KYNRDFESHITSYKQNPEQSADED--AEK 173
GKK+ NK+ L L +I K +S K+ +Q DED ++
Sbjct: 2 GKKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKE 61
Query: 174 NEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDT 233
EE S + D + V+ + E S + +K +K + D DSE+ ED D+
Sbjct: 62 LEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDS 121
Query: 234 GSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEE 293
S K+TA + D+D KK + KA+K + K EE+
Sbjct: 122 KS------------KKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSN--KKWDGSEED 167
Query: 294 EDNEGGEWERVR 305
EDN ER R
Sbjct: 168 EDNSKKIKERSR 179
>gi|4557509 cylicin 2 [Homo sapiens]
Length = 348
Score = 53.5 bits (127), Expect = 9e-07
Identities = 53/212 (25%), Positives = 99/212 (46%), Gaps = 40/212 (18%)
Query: 114 EDYLNELWEDKEGKKKMNKNNAKALSTLRQK--IRKYNRDFESHITSYKQNPEQSADE-- 169
E+ L+ + K+GKK K A + +K +K N+ + K + +S E
Sbjct: 152 EEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKG 211
Query: 170 ----DAEKNEEDSEGS-----------SDEDEDEDGVSAATFLKKKSEAPSGESRKFLKK 214
D++K ++DS+ +DE +DEDG K +A G+ K KK
Sbjct: 212 GTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDG---------KKDANKGDESKDAKK 262
Query: 215 MDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTAL-ASRFLKKAPTTDEDKKAAEKK 273
D E + +D + +S+DSDS+++ K++ A++ KK D +K++A+ K
Sbjct: 263 --DAKEIKKGKKDKKK----PSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSK 316
Query: 274 REDKAKKKHD-----RKSKRLDEEEEDNEGGE 300
++ K K D +K+ + DE+++ + G+
Sbjct: 317 KDAKKNAKKDAKKDAKKNAKKDEKKDAKKKGK 348
Score = 53.1 bits (126), Expect = 1e-06
Identities = 50/234 (21%), Positives = 102/234 (43%), Gaps = 21/234 (8%)
Query: 126 GKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDED 185
GKK +K K + ++++ +D + ++ E+ +E + ++ +G D +
Sbjct: 115 GKKGEDKTTQKDTTDSESELKQGKKDSKKG-----KDIEKGKEEKLDAKKDSKKGKKDAE 169
Query: 186 EDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDS--- 242
+ +D + +SE G ++K KK + +DS + + + G T DS
Sbjct: 170 KGKDSAT-------ESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKK 222
Query: 243 EEEEGKQTALASRFLKKAPTTDED-KKAAEKKREDKAKKKHDRKSKRLDEEEE-----DN 296
+ ++GK +A+ + +K DED KK A K E K KK ++ K+ ++++ D+
Sbjct: 223 DSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDS 282
Query: 297 EGGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQ 350
+ + + K+ K+ K TE A K + + KK + A+
Sbjct: 283 DSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAK 336
Score = 52.4 bits (124), Expect = 2e-06
Identities = 46/201 (22%), Positives = 85/201 (42%), Gaps = 6/201 (2%)
Query: 97 VDKEGVPRFYIRILADLEDYLNELWEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHI 156
+ K+G + + D E L + +D + K + K + L + +K +D E
Sbjct: 114 IGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDS-KKGKKDAEKGK 172
Query: 157 TSYKQNPEQS--ADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKK 214
S ++ ++ A +D +K+++DS D + +G T +K S+ +S+K
Sbjct: 173 DSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGT--EKDSKKGKKDSKKGKDS 230
Query: 215 MDDEDEDSEDSEDDEDWDTGSTSSD-SDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKK 273
+ D + DED + D S +++ K+ + KK +TD D K KK
Sbjct: 231 AIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKK 290
Query: 274 REDKAKKKHDRKSKRLDEEEE 294
K K +K + D E+E
Sbjct: 291 ESKKDATKDAKKVAKKDTEKE 311
Score = 39.7 bits (91), Expect = 0.013
Identities = 44/173 (25%), Positives = 72/173 (41%), Gaps = 22/173 (12%)
Query: 197 LKKKSEAPS---GESRKFLKKMDDEDEDSEDSE---DDEDWDTGSTSSDSDSEEEEGKQT 250
L + SE PS R+ LK + DS+ +E ED T ++DS+SE ++GK+
Sbjct: 81 LMRISERPSVYLAARRQPLKPTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKD 140
Query: 251 ALASRFLKKAPTTDEDKKAAEKKREDKAKK---------------KHDRKSKRLDEEEED 295
+ + ++K D K KK + A+K K D K + D +
Sbjct: 141 SKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGK 200
Query: 296 NEGGEWERVRGGVPLVKEKPKMFA-KGTEITHAVVIKKLNEILQARGKKGTDR 347
+ E E +GG +K K + KG + + K +E GKK ++
Sbjct: 201 DSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANK 253
>gi|157674363 protein phosphatase 1, regulatory subunit 15A [Homo
sapiens]
Length = 674
Score = 53.5 bits (127), Expect = 9e-07
Identities = 38/132 (28%), Positives = 62/132 (46%), Gaps = 12/132 (9%)
Query: 164 EQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSE 223
E + +E+ E+ +EDS+ SDE+E E S++T + FLK + E
Sbjct: 348 EDTEEEEDEEEDEDSDSGSDEEEGEAEASSST----------PATGVFLKSW--VYQPGE 395
Query: 224 DSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHD 283
D+E++ED D+ + S++ + E E T AS FLK + E+ + ++ K D
Sbjct: 396 DTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKED 455
Query: 284 RKSKRLDEEEED 295
L E E D
Sbjct: 456 DSEAALGEAESD 467
Score = 42.4 bits (98), Expect = 0.002
Identities = 36/134 (26%), Positives = 59/134 (44%), Gaps = 13/134 (9%)
Query: 163 PEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEA--------PSGESRKFLKK 214
P+ SA A++ + S DE+E V A +K EA PS + ++
Sbjct: 288 PQSSAP--AQRPQLKSWWCQPSDEEEGEVKALGAAEKDGEAECPPCIPPPSAFLKAWVYW 345
Query: 215 MDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKK-APTTDEDKKAAEKK 273
++ E+ ED E+DED D+G S + + E E T FLK ED + E +
Sbjct: 346 PGEDTEEEEDEEEDEDSDSG--SDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDE 403
Query: 274 REDKAKKKHDRKSK 287
D + +R+++
Sbjct: 404 DSDTGSAEDEREAE 417
>gi|197927454 DEK oncogene isoform 2 [Homo sapiens]
Length = 341
Score = 53.5 bits (127), Expect = 9e-07
Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 18/148 (12%)
Query: 125 EGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDE 184
+G KK ++ A R K + D E S+DED +KN+E+S D+
Sbjct: 168 KGSKKERNSSGMARKAKRTKCPEILSD------------ESSSDEDEKKNKEESSDDEDK 215
Query: 185 DEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEE 244
+ +E+ +K + + +S+K +K + + DS ++ +++ SS +SE
Sbjct: 216 ESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQN------SSKKESES 269
Query: 245 EEGKQTALASRFLKKAPTTDEDKKAAEK 272
E+ + LKK PT +E K+ +K
Sbjct: 270 EDSSDDEPLIKKLKKPPTDEELKETIKK 297
Score = 48.1 bits (113), Expect = 4e-05
Identities = 48/197 (24%), Positives = 79/197 (40%), Gaps = 32/197 (16%)
Query: 124 KEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSD 183
K+ + M K+ + L R + N + I ++ +P+ S + + S+GS
Sbjct: 116 KKFRNAMLKSICEVLDLERSGV---NSELVKRILNFLMHPKPSGKPLPKSKKTCSKGS-- 170
Query: 184 EDEDEDGVSAATFLKKKSEAPSGESRKFLK-KMDDEDEDSEDSEDDEDWDTGSTSSDSDS 242
KK SG +RK + K + D S++DE + +S D D
Sbjct: 171 ---------------KKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDK 215
Query: 243 EEEEGKQTALASRFLKKAPTTDEDK---KAAEKKREDKAKKKHDRKSKRLDEEEEDNEGG 299
E EE A R K T + K K+A K+ D + K ++ S + + E ED+
Sbjct: 216 ESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDD 275
Query: 300 EWERVRGGVPLVKEKPK 316
E PL+K+ K
Sbjct: 276 E--------PLIKKLKK 284
Score = 32.0 bits (71), Expect = 2.7
Identities = 21/89 (23%), Positives = 39/89 (43%), Gaps = 9/89 (10%)
Query: 122 EDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGS 181
EDKE +++ K AK ++ K + +S + ++++ K E +SE S
Sbjct: 213 EDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDS 272
Query: 182 SDEDEDEDGVSAATFLKKKSEAPSGESRK 210
SD++ +KK + P+ E K
Sbjct: 273 SDDE---------PLIKKLKKPPTDEELK 292
>gi|4503249 DEK oncogene isoform 1 [Homo sapiens]
Length = 375
Score = 53.5 bits (127), Expect = 9e-07
Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 18/148 (12%)
Query: 125 EGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDE 184
+G KK ++ A R K + D E S+DED +KN+E+S D+
Sbjct: 202 KGSKKERNSSGMARKAKRTKCPEILSD------------ESSSDEDEKKNKEESSDDEDK 249
Query: 185 DEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEE 244
+ +E+ +K + + +S+K +K + + DS ++ +++ SS +SE
Sbjct: 250 ESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQN------SSKKESES 303
Query: 245 EEGKQTALASRFLKKAPTTDEDKKAAEK 272
E+ + LKK PT +E K+ +K
Sbjct: 304 EDSSDDEPLIKKLKKPPTDEELKETIKK 331
Score = 48.9 bits (115), Expect = 2e-05
Identities = 71/343 (20%), Positives = 124/343 (36%), Gaps = 63/343 (18%)
Query: 11 SESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNA 70
S S + GE T+P + P E EE+ +++ +E + ++ R
Sbjct: 2 SASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEE-KEKSLIVEGKREK 60
Query: 71 MKIRDVTKCLEEF--ELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNELWEDKEGKK 128
K+ +T + E A GK + + + E + F + D L++L ++ G
Sbjct: 61 KKVERLTMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTV 120
Query: 129 KMNKNNAKALSTL------------RQKIRKY-------------------NRDFESHIT 157
K N S + ++K+ N + I
Sbjct: 121 SSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRIL 180
Query: 158 SYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLK-KMD 216
++ +P+ S + + S+GS KK SG +RK + K
Sbjct: 181 NFLMHPKPSGKPLPKSKKTCSKGS-----------------KKERNSSGMARKAKRTKCP 223
Query: 217 DEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDK---KAAEKK 273
+ D S++DE + +S D D E EE A R K T + K K+A K
Sbjct: 224 EILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVK 283
Query: 274 REDKAKKKHDRKSKRLDEEEEDNEGGEWERVRGGVPLVKEKPK 316
+ D + K ++ S + + E ED+ E PL+K+ K
Sbjct: 284 KADSSTTKKNQNSSKKESESEDSSDDE--------PLIKKLKK 318
Score = 32.0 bits (71), Expect = 2.7
Identities = 21/89 (23%), Positives = 39/89 (43%), Gaps = 9/89 (10%)
Query: 122 EDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGS 181
EDKE +++ K AK ++ K + +S + ++++ K E +SE S
Sbjct: 247 EDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDS 306
Query: 182 SDEDEDEDGVSAATFLKKKSEAPSGESRK 210
SD++ +KK + P+ E K
Sbjct: 307 SDDE---------PLIKKLKKPPTDEELK 326
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,755,505
Number of Sequences: 37866
Number of extensions: 1656444
Number of successful extensions: 24723
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 388
Number of HSP's successfully gapped in prelim test: 735
Number of HSP's that attempted gapping in prelim test: 10707
Number of HSP's gapped (non-prelim): 6657
length of query: 913
length of database: 18,247,518
effective HSP length: 111
effective length of query: 802
effective length of database: 14,044,392
effective search space: 11263602384
effective search space used: 11263602384
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.