Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 82880654
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|82880654 coiled-coil domain containing 46 isoform b [Homo
sapiens]
(211 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|82880654 coiled-coil domain containing 46 isoform b [Homo sap... 404 e-113
gi|82880656 coiled-coil domain containing 46 isoform a [Homo sap... 301 3e-82
gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens] 54 7e-08
gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens] 53 2e-07
gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens] 53 2e-07
gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens] 53 2e-07
gi|113425121 PREDICTED: similar to Golgin subfamily A member 8-l... 52 3e-07
gi|113425145 PREDICTED: similar to Golgin subfamily A member 8-l... 52 4e-07
gi|113425137 PREDICTED: similar to Golgin subfamily A member 8-l... 52 4e-07
gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens] 52 5e-07
gi|239745114 PREDICTED: Golgin subfamily A member 8-like protein... 51 8e-07
gi|4503593 epidermal growth factor receptor pathway substrate 15... 50 1e-06
gi|113425119 PREDICTED: similar to golgi autoantigen, golgin sub... 50 1e-06
gi|239745147 PREDICTED: similar to Golgin subfamily A member 8-l... 50 1e-06
gi|239745111 PREDICTED: Golgin subfamily A member 8-like protein... 50 1e-06
gi|239745099 PREDICTED: similar to Golgin subfamily A member 8-l... 49 4e-06
gi|4502443 dystonin isoform 1e precursor [Homo sapiens] 48 5e-06
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 48 7e-06
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 48 7e-06
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 48 7e-06
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 48 7e-06
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 48 7e-06
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 48 7e-06
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 48 7e-06
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 48 7e-06
gi|10864047 epidermal growth factor receptor pathway substrate 1... 48 7e-06
gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens] 48 7e-06
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 47 1e-05
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 47 1e-05
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 47 1e-05
>gi|82880654 coiled-coil domain containing 46 isoform b [Homo
sapiens]
Length = 211
Score = 404 bits (1039), Expect = e-113
Identities = 211/211 (100%), Positives = 211/211 (100%)
Query: 1 MWASLSLDHPSAKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLK 60
MWASLSLDHPSAKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLK
Sbjct: 1 MWASLSLDHPSAKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLK 60
Query: 61 QIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDN 120
QIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDN
Sbjct: 61 QIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDN 120
Query: 121 DQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELE 180
DQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELE
Sbjct: 121 DQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELE 180
Query: 181 DTISSLKSQVNFLQKRASILQEELTTYQGRR 211
DTISSLKSQVNFLQKRASILQEELTTYQGRR
Sbjct: 181 DTISSLKSQVNFLQKRASILQEELTTYQGRR 211
>gi|82880656 coiled-coil domain containing 46 isoform a [Homo
sapiens]
Length = 955
Score = 301 bits (771), Expect = 3e-82
Identities = 170/214 (79%), Positives = 177/214 (82%), Gaps = 13/214 (6%)
Query: 11 SAKENQALRLIEMREENGNVPKTEQ---AGSLKPLRDTGKSNLKE----------KKANS 57
S ++ Q + L +REE E LK + K LK+ +KANS
Sbjct: 742 SQRKQQLVELGLLREEEKQRATREHEIVVNKLKAESEKMKIELKKTHAAETEMTLEKANS 801
Query: 58 KLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLI 117
KLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLI
Sbjct: 802 KLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLI 861
Query: 118 RDNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQ 177
RDNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQ
Sbjct: 862 RDNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQ 921
Query: 178 ELEDTISSLKSQVNFLQKRASILQEELTTYQGRR 211
ELEDTISSLKSQVNFLQKRASILQEELTTYQGRR
Sbjct: 922 ELEDTISSLKSQVNFLQKRASILQEELTTYQGRR 955
Score = 51.2 bits (121), Expect = 6e-07
Identities = 27/112 (24%), Positives = 58/112 (51%)
Query: 50 LKEKKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKF 109
L + K ++ + +++E+ +K+S +I EL+ + LK++ + +L +++L+D KF
Sbjct: 479 LLQTKYDADINLLKQEHALSASKASSMIEELEQNVCQLKQQLQESELQRKQQLRDQENKF 538
Query: 110 EDEKKQLIRDNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQ 161
+ EK L ++ LQ EL+ + K + E +EQ+T + +
Sbjct: 539 QMEKSHLKHIYEKKAHDLQSELDKGKEDTQKKIHKFEEALKEKEEQLTRVTE 590
Score = 45.8 bits (107), Expect = 3e-05
Identities = 42/180 (23%), Positives = 87/180 (48%), Gaps = 7/180 (3%)
Query: 14 ENQALRL-IEMREENGNVPKTEQAGSLKPLRDTGKS--NLKEKKANSKLKQIEKEYTQKL 70
E Q + L +E +E ++ + A +RD + NL EK+ + + E + +
Sbjct: 658 EQQIVELKLEHEQEKTHLLQQHNAEKDSLVRDHEREIENL-EKQLRAANMEHENQIQEFK 716
Query: 71 AKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDE 130
+ +Q+IA+++ + L+EE +++L ++ E+EK++ R+++ + L+ E
Sbjct: 717 KRDAQVIADMEAQVHKLREELINVNSQRKQQLVELGLLREEEKQRATREHEIVVNKLKAE 776
Query: 131 LENRSNQVRCAEKKLQHKELE-SQEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQ 189
E +++ LE + ++ I +EY KL + + EL+ TISSLK +
Sbjct: 777 SEKMKIELKKTHAAETEMTLEKANSKLKQIEKEYTQKL--AKSSQIIAELQTTISSLKEE 834
Score = 43.9 bits (102), Expect = 1e-04
Identities = 42/186 (22%), Positives = 85/186 (45%), Gaps = 19/186 (10%)
Query: 22 EMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAELQ 81
EM +E ++ K + L DT N +L ++E EY + ++ +I EL+
Sbjct: 365 EMEQEKFDLQKQHTENIQELLEDT----------NVRLNKMESEYMAQTQSTNHMIKELE 414
Query: 82 TTISSLKEENSQQQLAAERRLQDVRQKFEDEK-KQLIRDNDQAIKVLQDEL-ENRSNQVR 139
+ L E L ++ +Q +K E E+ Q+ Q +K ++ L + + + V
Sbjct: 415 ARVQQLTGEAENSNLQRQKLIQ---EKAELERCYQITCSELQEVKARRNTLHKEKDHLVN 471
Query: 140 CAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQV--NFLQKRA 197
E+ ++ + + I ++QE+ L +S+ +ELE + LK Q+ + LQ++
Sbjct: 472 DYEQNMKLLQTKYDADINLLKQEH--ALSASKASSMIEELEQNVCQLKQQLQESELQRKQ 529
Query: 198 SILQEE 203
+ +E
Sbjct: 530 QLRDQE 535
Score = 39.7 bits (91), Expect = 0.002
Identities = 39/156 (25%), Positives = 77/156 (49%), Gaps = 25/156 (16%)
Query: 50 LKEKKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKF 109
L+E K +L EK Y + + ++ A+L T SL+E+ S++ L +L+D+RQ++
Sbjct: 603 LEEFKRQVELNS-EKVYAEMKEQMEKVEADL-TRSKSLREKQSKEFLW---QLEDIRQRY 657
Query: 110 -----------EDEKKQLIR----DNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQE 154
E EK L++ + D ++ + E+EN Q+R A + +++ E ++
Sbjct: 658 EQQIVELKLEHEQEKTHLLQQHNAEKDSLVRDHEREIENLEKQLRAANMEHENQIQEFKK 717
Query: 155 QITYIRQEYETKLKGLMPASLRQELEDTISSLKSQV 190
+ + + E ++ LR+EL + S K Q+
Sbjct: 718 RDAQVIADMEAQVH-----KLREELINVNSQRKQQL 748
Score = 34.3 bits (77), Expect = 0.079
Identities = 37/142 (26%), Positives = 70/142 (49%), Gaps = 16/142 (11%)
Query: 47 KSNLK---EKKANSKLKQIEK--EYTQK-LAKSSQIIAELQTTISSLKEENSQQQLAAER 100
KS+LK EKKA+ +++K E TQK + K + + E + ++ + E Q A+
Sbjct: 542 KSHLKHIYEKKAHDLQSELDKGKEDTQKKIHKFEEALKEKEEQLTRVTEVQRLQAQQADA 601
Query: 101 RLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIR 160
L++ +++ E +++ + + ++ ++ +L RS +R + K E Q+ IR
Sbjct: 602 ALEEFKRQVELNSEKVYAEMKEQMEKVEADL-TRSKSLREKQSK------EFLWQLEDIR 654
Query: 161 QEYETKLKGLMPASLRQELEDT 182
Q YE ++ L L E E T
Sbjct: 655 QRYEQQIVEL---KLEHEQEKT 673
Score = 33.9 bits (76), Expect = 0.10
Identities = 41/176 (23%), Positives = 82/176 (46%), Gaps = 23/176 (13%)
Query: 24 REENGNV-PKTEQAGSLKPLRDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAELQT 82
RE+ N+ PK + S K S++ E + NS IE + + I L T
Sbjct: 177 REDGQNITPKICEVYSKKSPVSLDDSDI-EARLNSWNLGIENP---RYLRQKPIPVSLMT 232
Query: 83 TISSLKEENS-----------QQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDEL 131
SL++ +S +++L + ++ + KF +EK +L + +D + Q L
Sbjct: 233 PKFSLRKSSSFHDDHFLSRIREKELDMKTKMMEA--KFHEEKLKLQQKHDADV---QKIL 287
Query: 132 ENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLK 187
E ++N++ + + K+ E++E I + ++ +T ++ +R+ ED I+ LK
Sbjct: 288 ERKNNEIEELKTLYRSKQHETEETIRKLEKKVQTLIRDCQ--VIRETKEDQIAELK 341
>gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens]
Length = 438
Score = 54.3 bits (129), Expect = 7e-08
Identities = 45/211 (21%), Positives = 99/211 (46%), Gaps = 28/211 (13%)
Query: 20 LIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAE 79
L+++ EN N+ +Q +L+ + L+EK+ ++ Q+E + + +SSQ
Sbjct: 178 LVDVTLENSNIK--DQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQ---- 231
Query: 80 LQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQD---------- 129
+ ++E + E +LQ+ ++K EK+ L+ + + +K +++
Sbjct: 232 -EANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEI 290
Query: 130 ELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLR---QELEDTISSL 186
LE + ++ ++ ++ E E + Q+ E+ET++ G + S + Q+LE+ +SL
Sbjct: 291 SLEEKDQRIGELDRLIERMEKE-RHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASL 349
Query: 187 KSQVNFL-------QKRASILQEELTTYQGR 210
+ ++ L QK+ + EE Q R
Sbjct: 350 RERIRHLDDMVHCQQKKVKQMVEENNELQSR 380
Score = 42.0 bits (97), Expect = 4e-04
Identities = 41/172 (23%), Positives = 76/172 (44%), Gaps = 17/172 (9%)
Query: 14 ENQALRL-IEMREENGNVPKTEQAGSL-----KPLRDTGKSNLKEKKA-----NSKLKQI 62
ENQ L++ +E +E E L + L++ + + EK+A NS LK I
Sbjct: 219 ENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAI 278
Query: 63 EKEYTQ------KLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQL 116
E+ + L + Q I EL I +++E Q QL ++ + D K+
Sbjct: 279 EEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKER 338
Query: 117 IRDNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLK 168
+ ++A L++ + + + V C +KK++ E+ E + + ET+ K
Sbjct: 339 YQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTETQAK 390
>gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens]
Length = 445
Score = 53.1 bits (126), Expect = 2e-07
Identities = 43/205 (20%), Positives = 98/205 (47%), Gaps = 28/205 (13%)
Query: 20 LIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAE 79
L+++ EN N+ +Q +L+ + L+EK+ ++ Q+E + + +SSQ
Sbjct: 178 LVDVTLENSNIK--DQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQ---- 231
Query: 80 LQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQD---------- 129
+ ++E + E +LQ+ ++K EK+ L+ + + +K +++
Sbjct: 232 -EANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEI 290
Query: 130 ELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLR---QELEDTISSL 186
LE + ++ ++ ++ E E + Q+ E+ET++ G + S + Q+LE+ +SL
Sbjct: 291 SLEEKDQRIGELDRLIERMEKE-RHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASL 349
Query: 187 KSQVNFL-------QKRASILQEEL 204
+ ++ L QK+ + EE+
Sbjct: 350 RERIRHLDDMVHCQQKKVKQMVEEI 374
Score = 46.2 bits (108), Expect = 2e-05
Identities = 50/206 (24%), Positives = 92/206 (44%), Gaps = 27/206 (13%)
Query: 14 ENQALRL-IEMREENGNVPKTEQAGSL-----KPLRDTGKSNLKEKKA-----NSKLKQI 62
ENQ L++ +E +E E L + L++ + + EK+A NS LK I
Sbjct: 219 ENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAI 278
Query: 63 EKEYTQ------KLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQL 116
E+ + L + Q I EL I +++E Q QL ++ + D K+
Sbjct: 279 EEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKER 338
Query: 117 IRDNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLR 176
+ ++A L++ + + + V C +KK++ + E+I ++++ + K L
Sbjct: 339 YQQLEEASASLRERIRHLDDMVHCQQKKVK----QMVEEIESLKKKLQQK------QLLI 388
Query: 177 QELEDTISSLKSQVNFLQKRASILQE 202
+L + IS L+ + N LQ R L E
Sbjct: 389 LQLLEKISFLEGENNELQSRLDYLTE 414
>gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens]
Length = 550
Score = 53.1 bits (126), Expect = 2e-07
Identities = 43/205 (20%), Positives = 98/205 (47%), Gaps = 28/205 (13%)
Query: 20 LIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAE 79
L+++ EN N+ +Q +L+ + L+EK+ ++ Q+E + + +SSQ
Sbjct: 178 LVDVTLENSNIK--DQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQ---- 231
Query: 80 LQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQD---------- 129
+ ++E + E +LQ+ ++K EK+ L+ + + +K +++
Sbjct: 232 -EANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEI 290
Query: 130 ELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLR---QELEDTISSL 186
LE + ++ ++ ++ E E + Q+ E+ET++ G + S + Q+LE+ +SL
Sbjct: 291 SLEEKDQRIGELDRLIERMEKE-RHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASL 349
Query: 187 KSQVNFL-------QKRASILQEEL 204
+ ++ L QK+ + EE+
Sbjct: 350 RERIRHLDDMVHCQQKKVKQMVEEI 374
Score = 46.2 bits (108), Expect = 2e-05
Identities = 50/206 (24%), Positives = 92/206 (44%), Gaps = 27/206 (13%)
Query: 14 ENQALRL-IEMREENGNVPKTEQAGSL-----KPLRDTGKSNLKEKKA-----NSKLKQI 62
ENQ L++ +E +E E L + L++ + + EK+A NS LK I
Sbjct: 219 ENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAI 278
Query: 63 EKEYTQ------KLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQL 116
E+ + L + Q I EL I +++E Q QL ++ + D K+
Sbjct: 279 EEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKER 338
Query: 117 IRDNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLR 176
+ ++A L++ + + + V C +KK++ + E+I ++++ + K L
Sbjct: 339 YQQLEEASASLRERIRHLDDMVHCQQKKVK----QMVEEIESLKKKLQQK------QLLI 388
Query: 177 QELEDTISSLKSQVNFLQKRASILQE 202
+L + IS L+ + N LQ R L E
Sbjct: 389 LQLLEKISFLEGENNELQSRLDYLTE 414
>gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens]
Length = 466
Score = 53.1 bits (126), Expect = 2e-07
Identities = 43/205 (20%), Positives = 98/205 (47%), Gaps = 28/205 (13%)
Query: 20 LIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAE 79
L+++ EN N+ +Q +L+ + L+EK+ ++ Q+E + + +SSQ
Sbjct: 178 LVDVTLENSNIK--DQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQ---- 231
Query: 80 LQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQD---------- 129
+ ++E + E +LQ+ ++K EK+ L+ + + +K +++
Sbjct: 232 -EANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEI 290
Query: 130 ELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLR---QELEDTISSL 186
LE + ++ ++ ++ E E + Q+ E+ET++ G + S + Q+LE+ +SL
Sbjct: 291 SLEEKDQRIGELDRLIERMEKE-RHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASL 349
Query: 187 KSQVNFL-------QKRASILQEEL 204
+ ++ L QK+ + EE+
Sbjct: 350 RERIRHLDDMVHCQQKKVKQMVEEI 374
Score = 46.2 bits (108), Expect = 2e-05
Identities = 50/206 (24%), Positives = 92/206 (44%), Gaps = 27/206 (13%)
Query: 14 ENQALRL-IEMREENGNVPKTEQAGSL-----KPLRDTGKSNLKEKKA-----NSKLKQI 62
ENQ L++ +E +E E L + L++ + + EK+A NS LK I
Sbjct: 219 ENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAI 278
Query: 63 EKEYTQ------KLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQL 116
E+ + L + Q I EL I +++E Q QL ++ + D K+
Sbjct: 279 EEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKER 338
Query: 117 IRDNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLR 176
+ ++A L++ + + + V C +KK++ + E+I ++++ + K L
Sbjct: 339 YQQLEEASASLRERIRHLDDMVHCQQKKVK----QMVEEIESLKKKLQQK------QLLI 388
Query: 177 QELEDTISSLKSQVNFLQKRASILQE 202
+L + IS L+ + N LQ R L E
Sbjct: 389 LQLLEKISFLEGENNELQSRLDYLTE 414
>gi|113425121 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 4 [Homo sapiens]
Length = 632
Score = 52.4 bits (124), Expect = 3e-07
Identities = 49/176 (27%), Positives = 87/176 (49%), Gaps = 19/176 (10%)
Query: 24 REENGNVPKTEQAGSLKPLRDTGKSNLKEKKANS-KLKQIE---KEYTQKLAKSSQIIAE 79
R+ NG++P+T +G +P D+ +E +S LK +E +E L +S I+
Sbjct: 36 RKTNGSIPETATSGGCQPPGDSATGFHREGPTSSATLKDLESPCQERAVVLDSTSVKISR 95
Query: 80 LQTTISSLKEENSQ--QQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQ 137
L+ TI SLK++ Q QL E++ + RQK E R+ + I+ L + E +
Sbjct: 96 LKNTIKSLKQQKKQVEHQLEEEKKANNERQKAE-------RELEVQIQTLIIQKEELNTD 148
Query: 138 VRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFL 193
+ E+ L++ E ES++ +R ++ + KG L + L I++ K + N L
Sbjct: 149 LYHMERSLRYFEEESKD--LAVRLQHSLQCKG----ELERALSAVIATEKKKANQL 198
Score = 33.1 bits (74), Expect = 0.18
Identities = 44/196 (22%), Positives = 86/196 (43%), Gaps = 35/196 (17%)
Query: 47 KSNLKEKKANSKLKQIEKEYTQK-----LAKSSQIIAELQTTISSLKEENSQQQLAAERR 101
K+ L + K + + Q+E++ + A+ Q ++++ I +LK+E Q RR
Sbjct: 221 KAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMLQEICTLKKEKQQDM----RR 276
Query: 102 LQDVRQKFEDEKKQLIRD---------NDQAIKVLQDELENRSNQVRCAEKKLQHKELES 152
++++ + K Q+ ++ ++ L+ ELE + +++ K QH L +
Sbjct: 277 VEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQSQVKNNQHISLLN 336
Query: 153 QEQITYIR-------------QEYETKLKGL-MPASLRQELEDTISS---LKSQVNFLQK 195
+ Q IR QE KL+ L P S+ +EL + S L+ QV LQ+
Sbjct: 337 RRQEERIREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQLEQQVKELQE 396
Query: 196 RASILQEELTTYQGRR 211
+ E + Q ++
Sbjct: 397 KLGEEHLEAASQQNQQ 412
Score = 32.7 bits (73), Expect = 0.23
Identities = 37/147 (25%), Positives = 65/147 (44%), Gaps = 19/147 (12%)
Query: 52 EKKANSKLKQIEKEYTQ-KLAKSSQIIAELQTTISSLKEENSQQQLAAE---RRLQDVRQ 107
EKK ++L K +T+ +L +S Q A L+ ++ LKE Q QL + ++ R
Sbjct: 191 EKKKANQLSSCSKAHTEWELEQSLQDQALLKAQLTQLKESFQQLQLERDECAEHIEGERA 250
Query: 108 KFEDEKKQLIRDNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQI----TYIRQEY 163
++ +++ Q I L+ E + +V E+ L + + E + + E
Sbjct: 251 RWHQRMSKML----QEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEV 306
Query: 164 ETKLKGLMPASLRQELEDTISSLKSQV 190
E + LR+ELE L+SQV
Sbjct: 307 ELQ-------HLRKELERVAGELQSQV 326
>gi|113425145 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 3 [Homo sapiens]
Length = 632
Score = 52.0 bits (123), Expect = 4e-07
Identities = 49/176 (27%), Positives = 86/176 (48%), Gaps = 19/176 (10%)
Query: 24 REENGNVPKTEQAGSLKPLRDTGKSNLKEKKANS-KLKQIE---KEYTQKLAKSSQIIAE 79
R+ NG++P+T +G +P D+ +E +S LK +E +E L +S I+
Sbjct: 36 RKTNGSIPETATSGGCQPPGDSATGFHREGPTSSATLKDLESPCQERAVVLDSTSVKISR 95
Query: 80 LQTTISSLKEENSQ--QQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQ 137
L+ TI SLK++ Q QL E++ + RQK E R+ + I+ L + E +
Sbjct: 96 LKNTIKSLKQQKKQVEHQLEEEKKANNERQKAE-------RELEVQIQTLIIQKEELNTD 148
Query: 138 VRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFL 193
+ E+ L++ E ES++ +R ++ + KG L L I++ K + N L
Sbjct: 149 LYHMERSLRYFEEESKD--LAVRLQHSLQCKG----ELESALSAVIATEKKKANQL 198
Score = 33.9 bits (76), Expect = 0.10
Identities = 44/196 (22%), Positives = 86/196 (43%), Gaps = 35/196 (17%)
Query: 47 KSNLKEKKANSKLKQIEKEYTQK-----LAKSSQIIAELQTTISSLKEENSQQQLAAERR 101
K+ L + K + + Q+E++ + A+ Q ++++ I +LK+E Q RR
Sbjct: 221 KAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMSQEICTLKKEKQQDM----RR 276
Query: 102 LQDVRQKFEDEKKQLIRD---------NDQAIKVLQDELENRSNQVRCAEKKLQHKELES 152
++++ + K Q+ ++ ++ L+ ELE + +++ K QH L +
Sbjct: 277 VEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQSQVKNNQHISLLN 336
Query: 153 QEQITYIR-------------QEYETKLKGL-MPASLRQELEDTISS---LKSQVNFLQK 195
+ Q IR QE KL+ L P S+ +EL + S L+ QV LQ+
Sbjct: 337 RRQEERIREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQLEQQVKELQE 396
Query: 196 RASILQEELTTYQGRR 211
+ E + Q ++
Sbjct: 397 KLGEEHLEAASQQNQQ 412
Score = 32.3 bits (72), Expect = 0.30
Identities = 39/147 (26%), Positives = 64/147 (43%), Gaps = 19/147 (12%)
Query: 52 EKKANSKLKQIEKEYTQ-KLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFE 110
EKK ++L K +T+ +L +S Q A L+ ++ LKE Q QL + + + E
Sbjct: 191 EKKKANQLSSCSKAHTEWELEQSLQDQALLKAQLTQLKESFQQLQLERD----ECAEHIE 246
Query: 111 DEK---KQLIRDNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQI----TYIRQEY 163
E+ Q + Q I L+ E + +V E+ L + + E + + E
Sbjct: 247 GERARWHQRMSKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEV 306
Query: 164 ETKLKGLMPASLRQELEDTISSLKSQV 190
E + LR+ELE L+SQV
Sbjct: 307 ELQ-------HLRKELERVAGELQSQV 326
>gi|113425137 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 3 [Homo sapiens]
Length = 632
Score = 52.0 bits (123), Expect = 4e-07
Identities = 49/176 (27%), Positives = 86/176 (48%), Gaps = 19/176 (10%)
Query: 24 REENGNVPKTEQAGSLKPLRDTGKSNLKEKKANS-KLKQIE---KEYTQKLAKSSQIIAE 79
R+ NG++P+T +G +P D+ +E +S LK +E +E L +S I+
Sbjct: 36 RKTNGSIPETATSGGCQPPGDSATGFHREGPTSSATLKDLESPCQERAVVLDSTSVKISR 95
Query: 80 LQTTISSLKEENSQ--QQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQ 137
L+ TI SLK++ Q QL E++ + RQK E R+ + I+ L + E +
Sbjct: 96 LKNTIKSLKQQKKQVEHQLEEEKKANNERQKAE-------RELEVQIQTLIIQKEELNTD 148
Query: 138 VRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFL 193
+ E+ L++ E ES++ +R ++ + KG L L I++ K + N L
Sbjct: 149 LYHMERSLRYFEEESKD--LAVRLQHSLQCKG----ELESALSAVIATEKKKANQL 198
Score = 33.9 bits (76), Expect = 0.10
Identities = 44/196 (22%), Positives = 86/196 (43%), Gaps = 35/196 (17%)
Query: 47 KSNLKEKKANSKLKQIEKEYTQK-----LAKSSQIIAELQTTISSLKEENSQQQLAAERR 101
K+ L + K + + Q+E++ + A+ Q ++++ I +LK+E Q RR
Sbjct: 221 KAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMSQEICTLKKEKQQDM----RR 276
Query: 102 LQDVRQKFEDEKKQLIRD---------NDQAIKVLQDELENRSNQVRCAEKKLQHKELES 152
++++ + K Q+ ++ ++ L+ ELE + +++ K QH L +
Sbjct: 277 VEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQSQVKNNQHISLLN 336
Query: 153 QEQITYIR-------------QEYETKLKGL-MPASLRQELEDTISS---LKSQVNFLQK 195
+ Q IR QE KL+ L P S+ +EL + S L+ QV LQ+
Sbjct: 337 RRQEERIREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQLEQQVKELQE 396
Query: 196 RASILQEELTTYQGRR 211
+ E + Q ++
Sbjct: 397 KLGEEHLEAASQQNQQ 412
Score = 32.3 bits (72), Expect = 0.30
Identities = 39/147 (26%), Positives = 64/147 (43%), Gaps = 19/147 (12%)
Query: 52 EKKANSKLKQIEKEYTQ-KLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFE 110
EKK ++L K +T+ +L +S Q A L+ ++ LKE Q QL + + + E
Sbjct: 191 EKKKANQLSSCSKAHTEWELEQSLQDQALLKAQLTQLKESFQQLQLERD----ECAEHIE 246
Query: 111 DEK---KQLIRDNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQI----TYIRQEY 163
E+ Q + Q I L+ E + +V E+ L + + E + + E
Sbjct: 247 GERARWHQRMSKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEV 306
Query: 164 ETKLKGLMPASLRQELEDTISSLKSQV 190
E + LR+ELE L+SQV
Sbjct: 307 ELQ-------HLRKELERVAGELQSQV 326
>gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens]
Length = 636
Score = 51.6 bits (122), Expect = 5e-07
Identities = 50/184 (27%), Positives = 87/184 (47%), Gaps = 16/184 (8%)
Query: 28 GNVPKTEQAGSLKP---LRDTGKSNLKE--KKANSKLKQIEKEYTQKLAKSSQIIAELQT 82
G VP+ G+ + + + +S L E K+ + + ++++Y QK+ + Q +A+LQ
Sbjct: 288 GKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQK 347
Query: 83 TISSLKEENSQQQLAAERRLQDVRQKFEDE---KKQL---IRDNDQAIKVLQDELENRSN 136
++ L+ E Q+Q +R+L + K E E K+QL ++ Q +K LQD+L +
Sbjct: 348 QVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTR 407
Query: 137 QVRCAEKKLQ--HKELESQEQITYIRQEYETKL---KGLMPASLRQELEDTISSLKSQVN 191
Q EK++Q +K LE I T +G +QEL LK QV
Sbjct: 408 QREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVK 467
Query: 192 FLQK 195
++
Sbjct: 468 IFEE 471
>gi|239745114 PREDICTED: Golgin subfamily A member 8-like protein 3
[Homo sapiens]
Length = 580
Score = 50.8 bits (120), Expect = 8e-07
Identities = 54/221 (24%), Positives = 97/221 (43%), Gaps = 39/221 (17%)
Query: 24 REENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSK-LKQIEKEYTQK---LAKSSQIIAE 79
R+ NG++P+ +G +P RD+ +E +S LK +E ++ L S I++
Sbjct: 36 RKTNGSIPEKATSGGCQPPRDSATGFHREGPTSSATLKDLESPCQERAVVLDSRSVEISQ 95
Query: 80 LQTTISSLKEENSQ--QQLAAERRLQDVRQKFED-----------EKKQLIRD------- 119
L+ TI SLK++ Q QL E++ + +QK + +K++L D
Sbjct: 96 LKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYHMKRS 155
Query: 120 --------NDQAIKVLQD-----ELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETK 166
D A+++ ELE+ + V +KK ++ ES +Q+ R EY
Sbjct: 156 LRYFEEKSKDLAVRLQHSLQRKGELESVLSNVMATQKKKANQFKESFQQVQLERDEYSEH 215
Query: 167 LKGLMP--ASLRQELEDTISSLKSQVNFLQKRASILQEELT 205
LKG +++ I +LK + +R L+ L+
Sbjct: 216 LKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEKLERSLS 256
Score = 33.1 bits (74), Expect = 0.18
Identities = 42/185 (22%), Positives = 79/185 (42%), Gaps = 28/185 (15%)
Query: 32 KTEQAGSLKPLRDTGKSNLKEKKANSKLKQIEK-EYTQKL----AKSSQIIAELQTTISS 86
K E L + T K + K + + Q+E+ EY++ L A+ Q + ++ I +
Sbjct: 177 KGELESVLSNVMATQKKKANQFKESFQQVQLERDEYSEHLKGERARWQQRMRKMSQEICT 236
Query: 87 LKEENSQQQLAAERRLQDVRQKFEDEKKQLIRD---------NDQAIKVLQDELENRSNQ 137
LK+E Q RR++ + + K Q+ ++ ++ L+ ELE + +
Sbjct: 237 LKKEKQQDM----RRVEKLERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGE 292
Query: 138 VRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRA 197
++ K Q L +Q Q IR++ E LR++ E+ I + L K
Sbjct: 293 LQAQVKNNQRISLLNQRQEERIREQEE---------RLRKQ-EERIQEQHKSLQQLAKPQ 342
Query: 198 SILQE 202
S+ +E
Sbjct: 343 SVFKE 347
>gi|4503593 epidermal growth factor receptor pathway substrate 15
isoform A [Homo sapiens]
Length = 896
Score = 50.4 bits (119), Expect = 1e-06
Identities = 51/203 (25%), Positives = 93/203 (45%), Gaps = 39/203 (19%)
Query: 8 DHPSAKENQALR--LIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQIEKE 65
D + KE L +++++ E NV + LK DT K E + Q E
Sbjct: 328 DFSAIKELDTLNNEIVDLQREKNNVEQ-----DLKEKEDTIKQRTSEVQDLQDEVQRENT 382
Query: 66 YTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIK 125
QKL Q + E L +E +Q+ E +L++VR+K +E Q I
Sbjct: 383 NLQKLQAQKQQVQE-------LLDELDEQKAQLEEQLKEVRKKCAEEA--------QLIS 427
Query: 126 VLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDTISS 185
L+ EL ++ +Q+ E++L +++E+++ ++QE ELE+++ S
Sbjct: 428 SLKAELTSQESQISTYEEEL----AKAREELSRLQQE-------------TAELEESVES 470
Query: 186 LKSQVNFLQKRASILQEELTTYQ 208
K+Q+ LQ+ Q+E+++ Q
Sbjct: 471 GKAQLEPLQQHLQDSQQEISSMQ 493
>gi|113425119 PREDICTED: similar to golgi autoantigen, golgin
subfamily a, 8E isoform 2 [Homo sapiens]
Length = 631
Score = 50.4 bits (119), Expect = 1e-06
Identities = 49/176 (27%), Positives = 86/176 (48%), Gaps = 19/176 (10%)
Query: 24 REENGNVPKTEQAGSLKPLRDTGKSNLKEKKANS-KLKQIE---KEYTQKLAKSSQIIAE 79
R+ NG++P+T +G +P D+ +E +S LK +E +E L +S I+
Sbjct: 36 RKTNGSIPETATSGGCQPPGDSATGFHREGPTSSATLKDLESPCQERAVVLDSTSVKISR 95
Query: 80 LQTTISSLKEENSQ--QQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQ 137
L+ TI SLK++ Q QL E++ + RQK E R + I+ L + E +
Sbjct: 96 LKNTIKSLKQQKKQVEHQLEEEKKANNERQKAE-------RVLEVQIQTLIIQKEELNTD 148
Query: 138 VRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFL 193
+ E+ L++ E ES++ +R ++ + KG L + L I++ K + N L
Sbjct: 149 LYHMERSLRYFEEESKD--LAVRLQHSLQCKG----ELERALSAVIATEKKKANQL 198
Score = 29.6 bits (65), Expect = 2.0
Identities = 33/142 (23%), Positives = 67/142 (47%), Gaps = 10/142 (7%)
Query: 52 EKKANSKLKQIEKEYTQ-KLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFE 110
EKK ++L K +T+ +L +S Q A L+ ++ LKE Q QL + + + +
Sbjct: 191 EKKKANQLSSCSKAHTEWELEQSLQDQALLKAQLTQLKESFQQLQLERDECAEHIEGERA 250
Query: 111 DEKKQLIRDNDQAIKVLQDELENR-SNQVRCAEKKLQHKELES-QEQITYIRQEYETKLK 168
+++ + + + + +++ + R Q+ + KL+++ E + + E E +
Sbjct: 251 RWHQRMSKMSQEICTLKKEKQDMRWVEQLEWSLSKLKNQTAEPLPPEPPAVPSEVELQ-- 308
Query: 169 GLMPASLRQELEDTISSLKSQV 190
LR+ELE L+SQV
Sbjct: 309 -----HLRKELERVAGELQSQV 325
Score = 29.3 bits (64), Expect = 2.6
Identities = 43/193 (22%), Positives = 87/193 (45%), Gaps = 30/193 (15%)
Query: 47 KSNLKEKKANSKLKQIEKEYTQK-----LAKSSQIIAELQTTISSLKEENSQQQLAAERR 101
K+ L + K + + Q+E++ + A+ Q ++++ I +LK+E +Q + +
Sbjct: 221 KAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMSQEICTLKKE--KQDMRWVEQ 278
Query: 102 LQDVRQKFEDEKKQLIRDNDQAI------KVLQDELENRSNQVRCAEKKLQHKELESQEQ 155
L+ K +++ + + A+ + L+ ELE + +++ K QH L ++ Q
Sbjct: 279 LEWSLSKLKNQTAEPLPPEPPAVPSEVELQHLRKELERVAGELQSQVKNNQHISLLNRRQ 338
Query: 156 ITYIR-------------QEYETKLKGL-MPASLRQELEDTISS---LKSQVNFLQKRAS 198
IR QE KL+ L P S+ +EL + S L+ QV LQ++
Sbjct: 339 EERIREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQLEQQVKELQEKLG 398
Query: 199 ILQEELTTYQGRR 211
E+ + Q ++
Sbjct: 399 EEHLEVASQQNQQ 411
>gi|239745147 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 isoform 1 [Homo sapiens]
Length = 630
Score = 50.1 bits (118), Expect = 1e-06
Identities = 46/185 (24%), Positives = 92/185 (49%), Gaps = 19/185 (10%)
Query: 24 REENGNVPKTEQAGSLKPLRDTGKSNLKEKKANS-KLKQIE---KEYTQKLAKSSQIIAE 79
R+ NG++P+ +G +P RD+ +E +S LK +E +E L S I++
Sbjct: 36 RKTNGSIPEKATSGGCQPPRDSATGFHREGPTSSATLKDLESPCQERAVVLDSRSVEISQ 95
Query: 80 LQTTISSLKEENSQ--QQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQ 137
L+ TI SLK++ Q QL E++ + +QK K+++ Q + + ++EL +
Sbjct: 96 LKNTIKSLKQQKKQVEHQLEEEKKANNKKQK----AKRVLEVQIQTLNIQKEEL---NTD 148
Query: 138 VRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRA 197
+ ++ L++ E +S++ +R ++ + KG L L + +++ K + N L R+
Sbjct: 149 LYHMKRSLRYFEEKSKD--LAVRLQHSLQRKG----ELESVLSNVMATQKKKANQLSSRS 202
Query: 198 SILQE 202
E
Sbjct: 203 KARTE 207
Score = 32.3 bits (72), Expect = 0.30
Identities = 38/178 (21%), Positives = 77/178 (43%), Gaps = 15/178 (8%)
Query: 39 LKPLRDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAA 98
+ L++T KS ++KK + EK+ K K+ +++ T++ KEE +
Sbjct: 93 ISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYHM 152
Query: 99 ERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITY 158
+R L + FE++ K L +++ + ELE+ + V +KK ++ + T
Sbjct: 153 KRSL----RYFEEKSKDLAVRLQHSLQ-RKGELESVLSNVMATQKKKANQLSSRSKARTE 207
Query: 159 IRQEYETKLKGLMPASLRQ----------ELEDTISSLKSQVNFLQKRASILQEELTT 206
+ E + + L+ L Q E ++ LK + Q+R + +E+ T
Sbjct: 208 WKLEQSMREEALLKVQLTQLKESFQQVQLERDEYSEHLKGERARWQQRMRKMSQEICT 265
>gi|239745111 PREDICTED: Golgin subfamily A member 8-like protein 3
isoform 1 [Homo sapiens]
Length = 632
Score = 50.1 bits (118), Expect = 1e-06
Identities = 46/185 (24%), Positives = 92/185 (49%), Gaps = 19/185 (10%)
Query: 24 REENGNVPKTEQAGSLKPLRDTGKSNLKEKKANS-KLKQIE---KEYTQKLAKSSQIIAE 79
R+ NG++P+ +G +P RD+ +E +S LK +E +E L S I++
Sbjct: 36 RKTNGSIPEKATSGGCQPPRDSATGFHREGPTSSATLKDLESPCQERAVVLDSRSVEISQ 95
Query: 80 LQTTISSLKEENSQ--QQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQ 137
L+ TI SLK++ Q QL E++ + +QK K+++ Q + + ++EL +
Sbjct: 96 LKNTIKSLKQQKKQVEHQLEEEKKANNKKQK----AKRVLEVQIQTLNIQKEEL---NTD 148
Query: 138 VRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRA 197
+ ++ L++ E +S++ +R ++ + KG L L + +++ K + N L R+
Sbjct: 149 LYHMKRSLRYFEEKSKD--LAVRLQHSLQRKG----ELESVLSNVMATQKKKANQLSSRS 202
Query: 198 SILQE 202
E
Sbjct: 203 KARTE 207
Score = 32.3 bits (72), Expect = 0.30
Identities = 38/178 (21%), Positives = 77/178 (43%), Gaps = 15/178 (8%)
Query: 39 LKPLRDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAA 98
+ L++T KS ++KK + EK+ K K+ +++ T++ KEE +
Sbjct: 93 ISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYHM 152
Query: 99 ERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITY 158
+R L + FE++ K L +++ + ELE+ + V +KK ++ + T
Sbjct: 153 KRSL----RYFEEKSKDLAVRLQHSLQ-RKGELESVLSNVMATQKKKANQLSSRSKARTE 207
Query: 159 IRQEYETKLKGLMPASLRQ----------ELEDTISSLKSQVNFLQKRASILQEELTT 206
+ E + + L+ L Q E ++ LK + Q+R + +E+ T
Sbjct: 208 WKLEQSMREEALLKVQLTQFKESFQQVQLERDEYSEHLKGERARWQQRMRKMSQEICT 265
Score = 31.6 bits (70), Expect = 0.51
Identities = 39/170 (22%), Positives = 75/170 (44%), Gaps = 28/170 (16%)
Query: 47 KSNLKEKKANSKLKQIEK-EYTQKL----AKSSQIIAELQTTISSLKEENSQQQLAAERR 101
K L + K + + Q+E+ EY++ L A+ Q + ++ I +LK+E Q RR
Sbjct: 221 KVQLTQFKESFQQVQLERDEYSEHLKGERARWQQRMRKMSQEICTLKKEKQQDM----RR 276
Query: 102 LQDVRQKFEDEKKQLIRD---------NDQAIKVLQDELENRSNQVRCAEKKLQHKELES 152
++ + + K Q+ ++ ++ L+ ELE + +++ K Q L +
Sbjct: 277 VEKLERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQVKNNQRISLLN 336
Query: 153 QEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASILQE 202
Q Q IR++ E LR++ E+ I + L K S+ +E
Sbjct: 337 QRQEERIREQEE---------RLRKQ-EERIQEQHKSLQQLAKPQSVFKE 376
>gi|239745099 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 isoform 1 [Homo sapiens]
Length = 632
Score = 48.5 bits (114), Expect = 4e-06
Identities = 45/176 (25%), Positives = 89/176 (50%), Gaps = 19/176 (10%)
Query: 24 REENGNVPKTEQAGSLKPLRDTGKSNLKEKKANS-KLKQIE---KEYTQKLAKSSQIIAE 79
R+ NG++P+T +G +P D+ +E +S LK +E +E L S I++
Sbjct: 36 RKTNGSIPQTATSGGCQPPGDSATGFHREGPTSSATLKDLESPCQERAVVLDSRSVEISQ 95
Query: 80 LQTTISSLKEENSQ--QQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQ 137
L+ TI SLK++ Q QL E++ + +QK K+++ Q + + ++EL +
Sbjct: 96 LKNTIKSLKQQKKQVEHQLEEEKKANNKKQK----AKRVLEVQLQTLNIQKEEL---NTD 148
Query: 138 VRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFL 193
+ ++ L++ E +S++ +R ++ + KG L L D +++ K + N L
Sbjct: 149 LYHMKRSLRYFEEKSKD--LAVRLQHSLQRKG----ELESVLSDVMATQKKKANQL 198
Score = 33.9 bits (76), Expect = 0.10
Identities = 43/193 (22%), Positives = 82/193 (42%), Gaps = 26/193 (13%)
Query: 39 LKPLRDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAA 98
+ L++T KS ++KK + EK+ K K+ +++ T++ KEE +
Sbjct: 93 ISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQLQTLNIQKEELNTDLYHM 152
Query: 99 ERRLQDVRQKFEDEKKQL---IRDNDQAIKVLQDEL---ENRSNQVRCAEK--------- 143
+R L+ +K +D +L ++ + VL D + + ++NQ+ K
Sbjct: 153 KRSLRYFEEKSKDLAVRLQHSLQRKGELESVLSDVMATQKKKANQLSSPSKAGTEWKLEQ 212
Query: 144 --------KLQHKEL-ESQEQITYIRQEYETKLKGLMP--ASLRQELEDTISSLKSQVNF 192
K+Q +L ES +Q+ R EY LKG +++ I +LK +
Sbjct: 213 SMREEALLKVQLTQLKESFQQVQLERDEYSEHLKGERARWQQRMRKMSQEICTLKKEKQQ 272
Query: 193 LQKRASILQEELT 205
+R L+ L+
Sbjct: 273 DMRRVEKLERSLS 285
Score = 32.3 bits (72), Expect = 0.30
Identities = 39/170 (22%), Positives = 75/170 (44%), Gaps = 28/170 (16%)
Query: 47 KSNLKEKKANSKLKQIEK-EYTQKL----AKSSQIIAELQTTISSLKEENSQQQLAAERR 101
K L + K + + Q+E+ EY++ L A+ Q + ++ I +LK+E Q RR
Sbjct: 221 KVQLTQLKESFQQVQLERDEYSEHLKGERARWQQRMRKMSQEICTLKKEKQQDM----RR 276
Query: 102 LQDVRQKFEDEKKQLIRD---------NDQAIKVLQDELENRSNQVRCAEKKLQHKELES 152
++ + + K Q+ ++ ++ L+ ELE + +++ K Q L +
Sbjct: 277 VEKLERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQVKNNQRISLLN 336
Query: 153 QEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASILQE 202
Q Q IR++ E LR++ E+ I + L K S+ +E
Sbjct: 337 QRQEERIREQEE---------RLRKQ-EERIQEQHKSLQQLAKPQSVFEE 376
>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
Length = 2649
Score = 48.1 bits (113), Expect = 5e-06
Identities = 50/190 (26%), Positives = 85/190 (44%), Gaps = 27/190 (14%)
Query: 25 EENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAELQTTI 84
EE +T + G+ L K+ + E NSKL T K+++ +++AEL+
Sbjct: 1105 EEIKRCKETSEHGAYSDLLQRQKATVLE---NSKL-------TGKISELERMVAELKKQK 1154
Query: 85 SSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQVRCAEKK 144
S ++EE + + AAE L+ ++ ED Q IR +A K + ELE + AE++
Sbjct: 1155 SRVEEELPKVREAAENELRKQQRNVEDISLQKIRAESEA-KQYRRELETIVREKEAAERE 1213
Query: 145 LQH----------KELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQ 194
L+ K +E + R + E R+ LED + +N L+
Sbjct: 1214 LERVRQLTIEAEAKRAAVEENLLNFRNQLEEN------TFTRRTLEDHLKRKDLSLNDLE 1267
Query: 195 KRASILQEEL 204
++ + L EEL
Sbjct: 1268 QQKNKLMEEL 1277
Score = 37.0 bits (84), Expect = 0.012
Identities = 49/210 (23%), Positives = 94/210 (44%), Gaps = 31/210 (14%)
Query: 15 NQALRLIEMREENGNVPKTEQAGSLKPL-----RDTGKSNLKEKKANSKLKQIEKEYTQK 69
N LR +++ E + + + L+ L + TGK+ ++A S LK+I++ Y +
Sbjct: 1414 NNTLRCLKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEA-SDLKKIKRNYQLE 1472
Query: 70 LAKSSQIIAELQ------TTISSLKEENSQQ---QLAAER------RLQDVRQKFEDEKK 114
L + +LQ T ++ E+N Q Q+ + R RLQ ++K + K+
Sbjct: 1473 LESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRDEKELERLQICQRKSDHLKE 1532
Query: 115 QLIRDNDQAIKVLQDELENRSNQVRC---AEKKLQHKELESQEQITYIRQEYETKLKGLM 171
Q + ++Q ++ ++ E EN R EK + E+ Q+ RQ ETKL
Sbjct: 1533 QFEKSHEQLLQNIKAEKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNETKL---- 1588
Query: 172 PASLRQELEDTISSLKSQVNFLQKRASILQ 201
+ Q ++ ++ + +Q+R L+
Sbjct: 1589 ---MMQRIQAESENIVLEKQTIQQRCEALK 1615
Score = 35.8 bits (81), Expect = 0.027
Identities = 36/148 (24%), Positives = 75/148 (50%), Gaps = 15/148 (10%)
Query: 14 ENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQIEKEYTQKL--- 70
E + L+LI+ E++ K K L++ K L+ ++ ++++ +E +
Sbjct: 1284 EEELLKLIKQMEKDLAFQKQVAE---KQLKEKQKIELEARRKITEIQYTCRENALPVCPI 1340
Query: 71 --AKSSQIIAELQTTISSLKEENSQQQL----AAERRL-QDVRQ-KFEDEKKQLIR-DND 121
A S + + LQ K E +QQ+ AA R+ QD+R+ +E QL + ++
Sbjct: 1341 TQATSCRAVTGLQQEHDKQKAEELKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSE 1400
Query: 122 QAIKVLQDELENRSNQVRCAEKKLQHKE 149
+ ++L+D+L+ +N +RC + +L+ K+
Sbjct: 1401 EKARLLKDKLDETNNTLRCLKLELERKD 1428
Score = 32.0 bits (71), Expect = 0.39
Identities = 33/148 (22%), Positives = 63/148 (42%), Gaps = 26/148 (17%)
Query: 49 NLK-EKKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQ 107
N+K EK+ N K++++ +E L KS++ L+ + L +N++ +L + Q
Sbjct: 1544 NIKAEKENNDKIQRLNEE----LEKSNECAEMLKQKVEELTRQNNETKL--------MMQ 1591
Query: 108 KFEDEKKQLIRDNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKL 167
+ + E + ++ LE ++ Q RC K+Q + Q + T +TK
Sbjct: 1592 RIQAESENIV-------------LEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQTKT 1638
Query: 168 KGLMPASLRQELEDTISSLKSQVNFLQK 195
+ ++ ED S F QK
Sbjct: 1639 EQDFQRKIKCLEEDLAKSQNLVSEFKQK 1666
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 47.8 bits (112), Expect = 7e-06
Identities = 38/165 (23%), Positives = 76/165 (46%), Gaps = 6/165 (3%)
Query: 3 ASLSLDHPSAKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQI 62
A L+ K Q +L++++ E + EQ L+ + +S L EK + L Q
Sbjct: 2451 AIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQL--LQETQALQQSFLSEKDS---LLQR 2505
Query: 63 EKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQ 122
E+ Q+ AK Q+ + L+EE +QQ E+ Q + E+ +++ + ++
Sbjct: 2506 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQ-HEAEE 2564
Query: 123 AIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKL 167
++ Q+EL+ Q R E+ L + +EQ+ + +++ L
Sbjct: 2565 GVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL 2609
Score = 45.1 bits (105), Expect = 4e-05
Identities = 50/211 (23%), Positives = 90/211 (42%), Gaps = 27/211 (12%)
Query: 11 SAKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEK----------KANSKLK 60
S +A RL ++ EE+ L R + LKEK KA ++L
Sbjct: 2284 SVAAQEAARLRQLAEED-----------LAQQRALAEKMLKEKMQAVQEATRLKAEAELL 2332
Query: 61 QIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDN 120
Q +KE Q+ A+ Q E + + + Q+ L AER+ Q + K + +
Sbjct: 2333 QQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEM 2392
Query: 121 DQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELE 180
+A +++ + Q +KL EL +QE++T ++ +++ + L
Sbjct: 2393 SRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQ---TLEIQRQQSDHDAERLR 2449
Query: 181 DTISSLKSQVNFLQKRASILQ---EELTTYQ 208
+ I+ L+ + LQ+ A +LQ EE+ T Q
Sbjct: 2450 EAIAELEREKEKLQQEAKLLQLKSEEMQTVQ 2480
Score = 44.7 bits (104), Expect = 6e-05
Identities = 50/187 (26%), Positives = 79/187 (42%), Gaps = 27/187 (14%)
Query: 3 ASLSLDHPSAKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQI 62
A L+ K N+ALRL EE QA + K + + + KA + +
Sbjct: 1627 AERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ 1686
Query: 63 EKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQ 122
+ Q+L K Q L E +QQ+LAAE+ L +R + E E+ +Q
Sbjct: 1687 RELAEQELEKQRQ-----------LAEGTAQQRLAAEQEL--IRLRAETEQ------GEQ 1727
Query: 123 AIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDT 182
++L++EL + A +K Q E E + +R E E L+ + R E E
Sbjct: 1728 QRQLLEEELARLQREAAAATQKRQELEAE----LAKVRAEMEV----LLASKARAEEESR 1779
Query: 183 ISSLKSQ 189
+S KS+
Sbjct: 1780 STSEKSK 1786
Score = 40.4 bits (93), Expect = 0.001
Identities = 43/170 (25%), Positives = 83/170 (48%), Gaps = 15/170 (8%)
Query: 43 RDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRL 102
R+ +S + ++A +LKQ +E Q A++ +L+ +Q + AA R+
Sbjct: 2102 REAAQSRRQVEEAE-RLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2160
Query: 103 QDVRQKFEDEKK---QLIRDN---DQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQI 156
Q + E KK Q +R +Q + L+ +LE +Q +++LQ + E+ E
Sbjct: 2161 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2220
Query: 157 TYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASILQEELTT 206
R + E +L S+R ++E+ +S LK+++ + RA IL+++ T
Sbjct: 2221 RQ-RSQVEEEL-----FSVRVQMEE-LSKLKARIE-AENRALILRDKDNT 2262
Score = 37.0 bits (84), Expect = 0.012
Identities = 41/190 (21%), Positives = 85/190 (44%), Gaps = 19/190 (10%)
Query: 39 LKPLRDTGKSNLKEKKANSKLKQ---IEKEYTQKLAKSSQIIAELQTTISSLKEEN--SQ 93
L+P+ K + + S +++ + Y++ +SQ I + T+ ++EE ++
Sbjct: 1293 LEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAE 1352
Query: 94 QQLAAER-RLQDVRQKFEDEKKQLIRDNDQA-------IKVLQDELENRSNQVRCAEKKL 145
QQ A ER RL +V E +++QL + QA K LQ ++ + A
Sbjct: 1353 QQRAEERERLAEVEAALE-KQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDA 1411
Query: 146 QHKELESQEQITYIRQEYETKLKGLMPAS-----LRQELEDTISSLKSQVNFLQKRASIL 200
Q ++ QE++ +RQ E +++ + R +E+ I ++ Q+ +++
Sbjct: 1412 QQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGA 1471
Query: 201 QEELTTYQGR 210
+ EL + R
Sbjct: 1472 EGELQALRAR 1481
Score = 33.5 bits (75), Expect = 0.14
Identities = 42/191 (21%), Positives = 80/191 (41%), Gaps = 42/191 (21%)
Query: 52 EKKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEE---NSQQQLAAERRLQDVRQK 108
++ A ++L+ + +K A+ + + E ++ L+EE +QQQ AER ++ ++
Sbjct: 1571 QRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERE 1630
Query: 109 FED---EKKQLIRDNDQAIKVLQ-------------DELENRSNQVRCAE------KKLQ 146
E + + +R QA +V Q +E E + + AE ++L
Sbjct: 1631 LERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELA 1690
Query: 147 HKELESQEQIT-------------YIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFL 193
+ELE Q Q+ IR ET+ RQ LE+ ++ L+ +
Sbjct: 1691 EQELEKQRQLAEGTAQQRLAAEQELIRLRAETE----QGEQQRQLLEEELARLQREAAAA 1746
Query: 194 QKRASILQEEL 204
++ L+ EL
Sbjct: 1747 TQKRQELEAEL 1757
Score = 33.5 bits (75), Expect = 0.14
Identities = 39/174 (22%), Positives = 81/174 (46%), Gaps = 18/174 (10%)
Query: 48 SNLKEKKANSKLKQIEKEYTQKLAKSS----QIIAELQTTISSLKEENSQQQLAAERRLQ 103
+ L+E+ +Q E E ++ A+ Q+ A + EE +QQ+ A+ +
Sbjct: 1604 AQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAE 1663
Query: 104 DVRQKFEDEKKQLIRDNDQAIK---VLQDELENR-------SNQVRCAEKKL--QHKELE 151
+++ E E ++ + +QA++ + + ELE + + Q AE++L E E
Sbjct: 1664 KQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETE 1723
Query: 152 SQEQITYIRQEYETKLKGLMPASL--RQELEDTISSLKSQVNFLQKRASILQEE 203
EQ + +E +L+ A+ RQELE ++ +++++ L + +EE
Sbjct: 1724 QGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEE 1777
Score = 32.7 bits (73), Expect = 0.23
Identities = 36/153 (23%), Positives = 71/153 (46%), Gaps = 13/153 (8%)
Query: 60 KQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQ-DVRQ----KFEDEKK 114
KQ+ E+ ++L +I+ +LQ +E+ +Q A+ LQ DVR K
Sbjct: 382 KQLRSEF-ERLECLQRIVTKLQMEAGLCEEQLNQ----ADALLQSDVRLLAAGKVPQRAG 436
Query: 115 QLIRDNDQA---IKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLM 171
++ RD D+A I++L ++++ + +++ + E++ IR EY +LK +
Sbjct: 437 EVERDLDKADSMIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGV 496
Query: 172 PASLRQELEDTISSLKSQVNFLQKRASILQEEL 204
A Q + T+ S++ + LQ+ L
Sbjct: 497 AAPATQVAQVTLQSVQRRPELEDSTLRYLQDLL 529
Score = 31.2 bits (69), Expect = 0.67
Identities = 37/174 (21%), Positives = 73/174 (41%), Gaps = 28/174 (16%)
Query: 19 RLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEK-KANSKLKQIEKEYTQKLAKSSQII 77
RL E + E +L+ R +++ + K +A + K++++ +++ + +
Sbjct: 1349 RLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAA 1408
Query: 78 AELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQA----------IKVL 127
+ Q S++EE LQ +RQ E E + R + A I+V+
Sbjct: 1409 VDAQQQKRSIQEE-----------LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVV 1457
Query: 128 QDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELED 181
+ +LE Q AE +LQ ++E RQ E + LR++++D
Sbjct: 1458 RLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAER------LRRQVQD 1505
Score = 29.6 bits (65), Expect = 2.0
Identities = 37/188 (19%), Positives = 82/188 (43%), Gaps = 15/188 (7%)
Query: 21 IEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAEL 80
++M E + + E LRD + ++ K+KQ+ +E +L+ ++Q A L
Sbjct: 2235 VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE-AARLSVAAQEAARL 2293
Query: 81 QTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQVRC 140
+ +E+ +QQ+ AE+ L++ Q ++ + ++LQ + E Q R
Sbjct: 2294 RQLA---EEDLAQQRALAEKMLKEKMQAVQEATRL-----KAEAELLQQQKELAQEQAR- 2344
Query: 141 AEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASIL 200
+LQ + + +Q+ Q ++ L+ L E+ LK +V + + +
Sbjct: 2345 ---RLQEDKEQMAQQLAEETQGFQRTLEAERQRQL--EMSAEAERLKLRVAEMSRAQARA 2399
Query: 201 QEELTTYQ 208
+E+ ++
Sbjct: 2400 EEDAQRFR 2407
Score = 28.5 bits (62), Expect = 4.4
Identities = 28/155 (18%), Positives = 67/155 (43%), Gaps = 19/155 (12%)
Query: 11 SAKENQALRLIEMREENGNVPKTEQAGSLKP-LRDTGKSNLKEKKANSKLKQIEKEYTQK 69
+A+E + R E R + + E A K L + + K ++A ++ E+E ++
Sbjct: 1976 AAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQ 2035
Query: 70 LAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQD 129
L L +E +Q++L AE + + ++++ Q +Q++ D
Sbjct: 2036 L---------------QLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVL---D 2077
Query: 130 ELENRSNQVRCAEKKLQHKELESQEQITYIRQEYE 164
+L + R A ++ + ++++ + R++ E
Sbjct: 2078 QLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVE 2112
Score = 28.1 bits (61), Expect = 5.7
Identities = 16/51 (31%), Positives = 27/51 (52%)
Query: 66 YTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQL 116
Y Q + + +LQ +L+ + S + A RL+D+ Q +DEK+QL
Sbjct: 724 YFQFFSDVREAEGQLQKLQEALRRKYSCDRSATVTRLEDLLQDAQDEKEQL 774
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 47.8 bits (112), Expect = 7e-06
Identities = 38/165 (23%), Positives = 76/165 (46%), Gaps = 6/165 (3%)
Query: 3 ASLSLDHPSAKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQI 62
A L+ K Q +L++++ E + EQ L+ + +S L EK + L Q
Sbjct: 2455 AIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQL--LQETQALQQSFLSEKDS---LLQR 2509
Query: 63 EKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQ 122
E+ Q+ AK Q+ + L+EE +QQ E+ Q + E+ +++ + ++
Sbjct: 2510 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQ-HEAEE 2568
Query: 123 AIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKL 167
++ Q+EL+ Q R E+ L + +EQ+ + +++ L
Sbjct: 2569 GVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL 2613
Score = 45.1 bits (105), Expect = 4e-05
Identities = 50/211 (23%), Positives = 90/211 (42%), Gaps = 27/211 (12%)
Query: 11 SAKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEK----------KANSKLK 60
S +A RL ++ EE+ L R + LKEK KA ++L
Sbjct: 2288 SVAAQEAARLRQLAEED-----------LAQQRALAEKMLKEKMQAVQEATRLKAEAELL 2336
Query: 61 QIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDN 120
Q +KE Q+ A+ Q E + + + Q+ L AER+ Q + K + +
Sbjct: 2337 QQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEM 2396
Query: 121 DQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELE 180
+A +++ + Q +KL EL +QE++T ++ +++ + L
Sbjct: 2397 SRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQ---TLEIQRQQSDHDAERLR 2453
Query: 181 DTISSLKSQVNFLQKRASILQ---EELTTYQ 208
+ I+ L+ + LQ+ A +LQ EE+ T Q
Sbjct: 2454 EAIAELEREKEKLQQEAKLLQLKSEEMQTVQ 2484
Score = 44.7 bits (104), Expect = 6e-05
Identities = 50/187 (26%), Positives = 79/187 (42%), Gaps = 27/187 (14%)
Query: 3 ASLSLDHPSAKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQI 62
A L+ K N+ALRL EE QA + K + + + KA + +
Sbjct: 1631 AERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ 1690
Query: 63 EKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQ 122
+ Q+L K Q L E +QQ+LAAE+ L +R + E E+ +Q
Sbjct: 1691 RELAEQELEKQRQ-----------LAEGTAQQRLAAEQEL--IRLRAETEQ------GEQ 1731
Query: 123 AIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDT 182
++L++EL + A +K Q E E + +R E E L+ + R E E
Sbjct: 1732 QRQLLEEELARLQREAAAATQKRQELEAE----LAKVRAEMEV----LLASKARAEEESR 1783
Query: 183 ISSLKSQ 189
+S KS+
Sbjct: 1784 STSEKSK 1790
Score = 40.4 bits (93), Expect = 0.001
Identities = 43/170 (25%), Positives = 83/170 (48%), Gaps = 15/170 (8%)
Query: 43 RDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRL 102
R+ +S + ++A +LKQ +E Q A++ +L+ +Q + AA R+
Sbjct: 2106 REAAQSRRQVEEAE-RLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2164
Query: 103 QDVRQKFEDEKK---QLIRDN---DQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQI 156
Q + E KK Q +R +Q + L+ +LE +Q +++LQ + E+ E
Sbjct: 2165 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2224
Query: 157 TYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASILQEELTT 206
R + E +L S+R ++E+ +S LK+++ + RA IL+++ T
Sbjct: 2225 RQ-RSQVEEEL-----FSVRVQMEE-LSKLKARIE-AENRALILRDKDNT 2266
Score = 37.0 bits (84), Expect = 0.012
Identities = 41/190 (21%), Positives = 85/190 (44%), Gaps = 19/190 (10%)
Query: 39 LKPLRDTGKSNLKEKKANSKLKQ---IEKEYTQKLAKSSQIIAELQTTISSLKEEN--SQ 93
L+P+ K + + S +++ + Y++ +SQ I + T+ ++EE ++
Sbjct: 1297 LEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAE 1356
Query: 94 QQLAAER-RLQDVRQKFEDEKKQLIRDNDQA-------IKVLQDELENRSNQVRCAEKKL 145
QQ A ER RL +V E +++QL + QA K LQ ++ + A
Sbjct: 1357 QQRAEERERLAEVEAALE-KQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDA 1415
Query: 146 QHKELESQEQITYIRQEYETKLKGLMPAS-----LRQELEDTISSLKSQVNFLQKRASIL 200
Q ++ QE++ +RQ E +++ + R +E+ I ++ Q+ +++
Sbjct: 1416 QQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGA 1475
Query: 201 QEELTTYQGR 210
+ EL + R
Sbjct: 1476 EGELQALRAR 1485
Score = 33.5 bits (75), Expect = 0.14
Identities = 42/191 (21%), Positives = 80/191 (41%), Gaps = 42/191 (21%)
Query: 52 EKKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEE---NSQQQLAAERRLQDVRQK 108
++ A ++L+ + +K A+ + + E ++ L+EE +QQQ AER ++ ++
Sbjct: 1575 QRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERE 1634
Query: 109 FED---EKKQLIRDNDQAIKVLQ-------------DELENRSNQVRCAE------KKLQ 146
E + + +R QA +V Q +E E + + AE ++L
Sbjct: 1635 LERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELA 1694
Query: 147 HKELESQEQIT-------------YIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFL 193
+ELE Q Q+ IR ET+ RQ LE+ ++ L+ +
Sbjct: 1695 EQELEKQRQLAEGTAQQRLAAEQELIRLRAETE----QGEQQRQLLEEELARLQREAAAA 1750
Query: 194 QKRASILQEEL 204
++ L+ EL
Sbjct: 1751 TQKRQELEAEL 1761
Score = 33.5 bits (75), Expect = 0.14
Identities = 39/174 (22%), Positives = 81/174 (46%), Gaps = 18/174 (10%)
Query: 48 SNLKEKKANSKLKQIEKEYTQKLAKSS----QIIAELQTTISSLKEENSQQQLAAERRLQ 103
+ L+E+ +Q E E ++ A+ Q+ A + EE +QQ+ A+ +
Sbjct: 1608 AQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAE 1667
Query: 104 DVRQKFEDEKKQLIRDNDQAIK---VLQDELENR-------SNQVRCAEKKL--QHKELE 151
+++ E E ++ + +QA++ + + ELE + + Q AE++L E E
Sbjct: 1668 KQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETE 1727
Query: 152 SQEQITYIRQEYETKLKGLMPASL--RQELEDTISSLKSQVNFLQKRASILQEE 203
EQ + +E +L+ A+ RQELE ++ +++++ L + +EE
Sbjct: 1728 QGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEE 1781
Score = 32.7 bits (73), Expect = 0.23
Identities = 36/153 (23%), Positives = 71/153 (46%), Gaps = 13/153 (8%)
Query: 60 KQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQ-DVRQ----KFEDEKK 114
KQ+ E+ ++L +I+ +LQ +E+ +Q A+ LQ DVR K
Sbjct: 386 KQLRSEF-ERLECLQRIVTKLQMEAGLCEEQLNQ----ADALLQSDVRLLAAGKVPQRAG 440
Query: 115 QLIRDNDQA---IKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLM 171
++ RD D+A I++L ++++ + +++ + E++ IR EY +LK +
Sbjct: 441 EVERDLDKADSMIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGV 500
Query: 172 PASLRQELEDTISSLKSQVNFLQKRASILQEEL 204
A Q + T+ S++ + LQ+ L
Sbjct: 501 AAPATQVAQVTLQSVQRRPELEDSTLRYLQDLL 533
Score = 31.2 bits (69), Expect = 0.67
Identities = 37/174 (21%), Positives = 73/174 (41%), Gaps = 28/174 (16%)
Query: 19 RLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEK-KANSKLKQIEKEYTQKLAKSSQII 77
RL E + E +L+ R +++ + K +A + K++++ +++ + +
Sbjct: 1353 RLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAA 1412
Query: 78 AELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQA----------IKVL 127
+ Q S++EE LQ +RQ E E + R + A I+V+
Sbjct: 1413 VDAQQQKRSIQEE-----------LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVV 1461
Query: 128 QDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELED 181
+ +LE Q AE +LQ ++E RQ E + LR++++D
Sbjct: 1462 RLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAER------LRRQVQD 1509
Score = 29.6 bits (65), Expect = 2.0
Identities = 37/188 (19%), Positives = 82/188 (43%), Gaps = 15/188 (7%)
Query: 21 IEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAEL 80
++M E + + E LRD + ++ K+KQ+ +E +L+ ++Q A L
Sbjct: 2239 VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE-AARLSVAAQEAARL 2297
Query: 81 QTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQVRC 140
+ +E+ +QQ+ AE+ L++ Q ++ + ++LQ + E Q R
Sbjct: 2298 RQLA---EEDLAQQRALAEKMLKEKMQAVQEATRL-----KAEAELLQQQKELAQEQAR- 2348
Query: 141 AEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASIL 200
+LQ + + +Q+ Q ++ L+ L E+ LK +V + + +
Sbjct: 2349 ---RLQEDKEQMAQQLAEETQGFQRTLEAERQRQL--EMSAEAERLKLRVAEMSRAQARA 2403
Query: 201 QEELTTYQ 208
+E+ ++
Sbjct: 2404 EEDAQRFR 2411
Score = 28.5 bits (62), Expect = 4.4
Identities = 28/155 (18%), Positives = 67/155 (43%), Gaps = 19/155 (12%)
Query: 11 SAKENQALRLIEMREENGNVPKTEQAGSLKP-LRDTGKSNLKEKKANSKLKQIEKEYTQK 69
+A+E + R E R + + E A K L + + K ++A ++ E+E ++
Sbjct: 1980 AAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQ 2039
Query: 70 LAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQD 129
L L +E +Q++L AE + + ++++ Q +Q++ D
Sbjct: 2040 L---------------QLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVL---D 2081
Query: 130 ELENRSNQVRCAEKKLQHKELESQEQITYIRQEYE 164
+L + R A ++ + ++++ + R++ E
Sbjct: 2082 QLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVE 2116
Score = 28.1 bits (61), Expect = 5.7
Identities = 16/51 (31%), Positives = 27/51 (52%)
Query: 66 YTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQL 116
Y Q + + +LQ +L+ + S + A RL+D+ Q +DEK+QL
Sbjct: 728 YFQFFSDVREAEGQLQKLQEALRRKYSCDRSATVTRLEDLLQDAQDEKEQL 778
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 47.8 bits (112), Expect = 7e-06
Identities = 38/165 (23%), Positives = 76/165 (46%), Gaps = 6/165 (3%)
Query: 3 ASLSLDHPSAKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQI 62
A L+ K Q +L++++ E + EQ L+ + +S L EK + L Q
Sbjct: 2451 AIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQL--LQETQALQQSFLSEKDS---LLQR 2505
Query: 63 EKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQ 122
E+ Q+ AK Q+ + L+EE +QQ E+ Q + E+ +++ + ++
Sbjct: 2506 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQ-HEAEE 2564
Query: 123 AIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKL 167
++ Q+EL+ Q R E+ L + +EQ+ + +++ L
Sbjct: 2565 GVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL 2609
Score = 45.1 bits (105), Expect = 4e-05
Identities = 50/211 (23%), Positives = 90/211 (42%), Gaps = 27/211 (12%)
Query: 11 SAKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEK----------KANSKLK 60
S +A RL ++ EE+ L R + LKEK KA ++L
Sbjct: 2284 SVAAQEAARLRQLAEED-----------LAQQRALAEKMLKEKMQAVQEATRLKAEAELL 2332
Query: 61 QIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDN 120
Q +KE Q+ A+ Q E + + + Q+ L AER+ Q + K + +
Sbjct: 2333 QQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEM 2392
Query: 121 DQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELE 180
+A +++ + Q +KL EL +QE++T ++ +++ + L
Sbjct: 2393 SRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQ---TLEIQRQQSDHDAERLR 2449
Query: 181 DTISSLKSQVNFLQKRASILQ---EELTTYQ 208
+ I+ L+ + LQ+ A +LQ EE+ T Q
Sbjct: 2450 EAIAELEREKEKLQQEAKLLQLKSEEMQTVQ 2480
Score = 44.7 bits (104), Expect = 6e-05
Identities = 50/187 (26%), Positives = 79/187 (42%), Gaps = 27/187 (14%)
Query: 3 ASLSLDHPSAKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQI 62
A L+ K N+ALRL EE QA + K + + + KA + +
Sbjct: 1627 AERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ 1686
Query: 63 EKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQ 122
+ Q+L K Q L E +QQ+LAAE+ L +R + E E+ +Q
Sbjct: 1687 RELAEQELEKQRQ-----------LAEGTAQQRLAAEQEL--IRLRAETEQ------GEQ 1727
Query: 123 AIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDT 182
++L++EL + A +K Q E E + +R E E L+ + R E E
Sbjct: 1728 QRQLLEEELARLQREAAAATQKRQELEAE----LAKVRAEMEV----LLASKARAEEESR 1779
Query: 183 ISSLKSQ 189
+S KS+
Sbjct: 1780 STSEKSK 1786
Score = 40.4 bits (93), Expect = 0.001
Identities = 43/170 (25%), Positives = 83/170 (48%), Gaps = 15/170 (8%)
Query: 43 RDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRL 102
R+ +S + ++A +LKQ +E Q A++ +L+ +Q + AA R+
Sbjct: 2102 REAAQSRRQVEEAE-RLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2160
Query: 103 QDVRQKFEDEKK---QLIRDN---DQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQI 156
Q + E KK Q +R +Q + L+ +LE +Q +++LQ + E+ E
Sbjct: 2161 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2220
Query: 157 TYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASILQEELTT 206
R + E +L S+R ++E+ +S LK+++ + RA IL+++ T
Sbjct: 2221 RQ-RSQVEEEL-----FSVRVQMEE-LSKLKARIE-AENRALILRDKDNT 2262
Score = 37.0 bits (84), Expect = 0.012
Identities = 41/190 (21%), Positives = 85/190 (44%), Gaps = 19/190 (10%)
Query: 39 LKPLRDTGKSNLKEKKANSKLKQ---IEKEYTQKLAKSSQIIAELQTTISSLKEEN--SQ 93
L+P+ K + + S +++ + Y++ +SQ I + T+ ++EE ++
Sbjct: 1293 LEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAE 1352
Query: 94 QQLAAER-RLQDVRQKFEDEKKQLIRDNDQA-------IKVLQDELENRSNQVRCAEKKL 145
QQ A ER RL +V E +++QL + QA K LQ ++ + A
Sbjct: 1353 QQRAEERERLAEVEAALE-KQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDA 1411
Query: 146 QHKELESQEQITYIRQEYETKLKGLMPAS-----LRQELEDTISSLKSQVNFLQKRASIL 200
Q ++ QE++ +RQ E +++ + R +E+ I ++ Q+ +++
Sbjct: 1412 QQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGA 1471
Query: 201 QEELTTYQGR 210
+ EL + R
Sbjct: 1472 EGELQALRAR 1481
Score = 33.5 bits (75), Expect = 0.14
Identities = 42/191 (21%), Positives = 80/191 (41%), Gaps = 42/191 (21%)
Query: 52 EKKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEE---NSQQQLAAERRLQDVRQK 108
++ A ++L+ + +K A+ + + E ++ L+EE +QQQ AER ++ ++
Sbjct: 1571 QRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERE 1630
Query: 109 FED---EKKQLIRDNDQAIKVLQ-------------DELENRSNQVRCAE------KKLQ 146
E + + +R QA +V Q +E E + + AE ++L
Sbjct: 1631 LERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELA 1690
Query: 147 HKELESQEQIT-------------YIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFL 193
+ELE Q Q+ IR ET+ RQ LE+ ++ L+ +
Sbjct: 1691 EQELEKQRQLAEGTAQQRLAAEQELIRLRAETE----QGEQQRQLLEEELARLQREAAAA 1746
Query: 194 QKRASILQEEL 204
++ L+ EL
Sbjct: 1747 TQKRQELEAEL 1757
Score = 33.5 bits (75), Expect = 0.14
Identities = 39/174 (22%), Positives = 81/174 (46%), Gaps = 18/174 (10%)
Query: 48 SNLKEKKANSKLKQIEKEYTQKLAKSS----QIIAELQTTISSLKEENSQQQLAAERRLQ 103
+ L+E+ +Q E E ++ A+ Q+ A + EE +QQ+ A+ +
Sbjct: 1604 AQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAE 1663
Query: 104 DVRQKFEDEKKQLIRDNDQAIK---VLQDELENR-------SNQVRCAEKKL--QHKELE 151
+++ E E ++ + +QA++ + + ELE + + Q AE++L E E
Sbjct: 1664 KQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETE 1723
Query: 152 SQEQITYIRQEYETKLKGLMPASL--RQELEDTISSLKSQVNFLQKRASILQEE 203
EQ + +E +L+ A+ RQELE ++ +++++ L + +EE
Sbjct: 1724 QGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEE 1777
Score = 32.7 bits (73), Expect = 0.23
Identities = 36/153 (23%), Positives = 71/153 (46%), Gaps = 13/153 (8%)
Query: 60 KQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQ-DVRQ----KFEDEKK 114
KQ+ E+ ++L +I+ +LQ +E+ +Q A+ LQ DVR K
Sbjct: 382 KQLRSEF-ERLECLQRIVTKLQMEAGLCEEQLNQ----ADALLQSDVRLLAAGKVPQRAG 436
Query: 115 QLIRDNDQA---IKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLM 171
++ RD D+A I++L ++++ + +++ + E++ IR EY +LK +
Sbjct: 437 EVERDLDKADSMIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGV 496
Query: 172 PASLRQELEDTISSLKSQVNFLQKRASILQEEL 204
A Q + T+ S++ + LQ+ L
Sbjct: 497 AAPATQVAQVTLQSVQRRPELEDSTLRYLQDLL 529
Score = 31.2 bits (69), Expect = 0.67
Identities = 37/174 (21%), Positives = 73/174 (41%), Gaps = 28/174 (16%)
Query: 19 RLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEK-KANSKLKQIEKEYTQKLAKSSQII 77
RL E + E +L+ R +++ + K +A + K++++ +++ + +
Sbjct: 1349 RLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAA 1408
Query: 78 AELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQA----------IKVL 127
+ Q S++EE LQ +RQ E E + R + A I+V+
Sbjct: 1409 VDAQQQKRSIQEE-----------LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVV 1457
Query: 128 QDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELED 181
+ +LE Q AE +LQ ++E RQ E + LR++++D
Sbjct: 1458 RLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAER------LRRQVQD 1505
Score = 29.6 bits (65), Expect = 2.0
Identities = 37/188 (19%), Positives = 82/188 (43%), Gaps = 15/188 (7%)
Query: 21 IEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAEL 80
++M E + + E LRD + ++ K+KQ+ +E +L+ ++Q A L
Sbjct: 2235 VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE-AARLSVAAQEAARL 2293
Query: 81 QTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQVRC 140
+ +E+ +QQ+ AE+ L++ Q ++ + ++LQ + E Q R
Sbjct: 2294 RQLA---EEDLAQQRALAEKMLKEKMQAVQEATRL-----KAEAELLQQQKELAQEQAR- 2344
Query: 141 AEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASIL 200
+LQ + + +Q+ Q ++ L+ L E+ LK +V + + +
Sbjct: 2345 ---RLQEDKEQMAQQLAEETQGFQRTLEAERQRQL--EMSAEAERLKLRVAEMSRAQARA 2399
Query: 201 QEELTTYQ 208
+E+ ++
Sbjct: 2400 EEDAQRFR 2407
Score = 28.5 bits (62), Expect = 4.4
Identities = 28/155 (18%), Positives = 67/155 (43%), Gaps = 19/155 (12%)
Query: 11 SAKENQALRLIEMREENGNVPKTEQAGSLKP-LRDTGKSNLKEKKANSKLKQIEKEYTQK 69
+A+E + R E R + + E A K L + + K ++A ++ E+E ++
Sbjct: 1976 AAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQ 2035
Query: 70 LAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQD 129
L L +E +Q++L AE + + ++++ Q +Q++ D
Sbjct: 2036 L---------------QLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVL---D 2077
Query: 130 ELENRSNQVRCAEKKLQHKELESQEQITYIRQEYE 164
+L + R A ++ + ++++ + R++ E
Sbjct: 2078 QLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVE 2112
Score = 28.1 bits (61), Expect = 5.7
Identities = 16/51 (31%), Positives = 27/51 (52%)
Query: 66 YTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQL 116
Y Q + + +LQ +L+ + S + A RL+D+ Q +DEK+QL
Sbjct: 724 YFQFFSDVREAEGQLQKLQEALRRKYSCDRSATVTRLEDLLQDAQDEKEQL 774
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 47.8 bits (112), Expect = 7e-06
Identities = 38/165 (23%), Positives = 76/165 (46%), Gaps = 6/165 (3%)
Query: 3 ASLSLDHPSAKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQI 62
A L+ K Q +L++++ E + EQ L+ + +S L EK + L Q
Sbjct: 2419 AIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQL--LQETQALQQSFLSEKDS---LLQR 2473
Query: 63 EKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQ 122
E+ Q+ AK Q+ + L+EE +QQ E+ Q + E+ +++ + ++
Sbjct: 2474 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQ-HEAEE 2532
Query: 123 AIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKL 167
++ Q+EL+ Q R E+ L + +EQ+ + +++ L
Sbjct: 2533 GVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL 2577
Score = 45.1 bits (105), Expect = 4e-05
Identities = 50/211 (23%), Positives = 90/211 (42%), Gaps = 27/211 (12%)
Query: 11 SAKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEK----------KANSKLK 60
S +A RL ++ EE+ L R + LKEK KA ++L
Sbjct: 2252 SVAAQEAARLRQLAEED-----------LAQQRALAEKMLKEKMQAVQEATRLKAEAELL 2300
Query: 61 QIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDN 120
Q +KE Q+ A+ Q E + + + Q+ L AER+ Q + K + +
Sbjct: 2301 QQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEM 2360
Query: 121 DQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELE 180
+A +++ + Q +KL EL +QE++T ++ +++ + L
Sbjct: 2361 SRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQ---TLEIQRQQSDHDAERLR 2417
Query: 181 DTISSLKSQVNFLQKRASILQ---EELTTYQ 208
+ I+ L+ + LQ+ A +LQ EE+ T Q
Sbjct: 2418 EAIAELEREKEKLQQEAKLLQLKSEEMQTVQ 2448
Score = 44.7 bits (104), Expect = 6e-05
Identities = 50/187 (26%), Positives = 79/187 (42%), Gaps = 27/187 (14%)
Query: 3 ASLSLDHPSAKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQI 62
A L+ K N+ALRL EE QA + K + + + KA + +
Sbjct: 1595 AERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ 1654
Query: 63 EKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQ 122
+ Q+L K Q L E +QQ+LAAE+ L +R + E E+ +Q
Sbjct: 1655 RELAEQELEKQRQ-----------LAEGTAQQRLAAEQEL--IRLRAETEQ------GEQ 1695
Query: 123 AIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDT 182
++L++EL + A +K Q E E + +R E E L+ + R E E
Sbjct: 1696 QRQLLEEELARLQREAAAATQKRQELEAE----LAKVRAEMEV----LLASKARAEEESR 1747
Query: 183 ISSLKSQ 189
+S KS+
Sbjct: 1748 STSEKSK 1754
Score = 40.4 bits (93), Expect = 0.001
Identities = 43/170 (25%), Positives = 83/170 (48%), Gaps = 15/170 (8%)
Query: 43 RDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRL 102
R+ +S + ++A +LKQ +E Q A++ +L+ +Q + AA R+
Sbjct: 2070 REAAQSRRQVEEAE-RLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2128
Query: 103 QDVRQKFEDEKK---QLIRDN---DQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQI 156
Q + E KK Q +R +Q + L+ +LE +Q +++LQ + E+ E
Sbjct: 2129 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2188
Query: 157 TYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASILQEELTT 206
R + E +L S+R ++E+ +S LK+++ + RA IL+++ T
Sbjct: 2189 RQ-RSQVEEEL-----FSVRVQMEE-LSKLKARIE-AENRALILRDKDNT 2230
Score = 37.0 bits (84), Expect = 0.012
Identities = 41/190 (21%), Positives = 85/190 (44%), Gaps = 19/190 (10%)
Query: 39 LKPLRDTGKSNLKEKKANSKLKQ---IEKEYTQKLAKSSQIIAELQTTISSLKEEN--SQ 93
L+P+ K + + S +++ + Y++ +SQ I + T+ ++EE ++
Sbjct: 1261 LEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAE 1320
Query: 94 QQLAAER-RLQDVRQKFEDEKKQLIRDNDQA-------IKVLQDELENRSNQVRCAEKKL 145
QQ A ER RL +V E +++QL + QA K LQ ++ + A
Sbjct: 1321 QQRAEERERLAEVEAALE-KQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDA 1379
Query: 146 QHKELESQEQITYIRQEYETKLKGLMPAS-----LRQELEDTISSLKSQVNFLQKRASIL 200
Q ++ QE++ +RQ E +++ + R +E+ I ++ Q+ +++
Sbjct: 1380 QQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGA 1439
Query: 201 QEELTTYQGR 210
+ EL + R
Sbjct: 1440 EGELQALRAR 1449
Score = 33.5 bits (75), Expect = 0.14
Identities = 42/191 (21%), Positives = 80/191 (41%), Gaps = 42/191 (21%)
Query: 52 EKKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEE---NSQQQLAAERRLQDVRQK 108
++ A ++L+ + +K A+ + + E ++ L+EE +QQQ AER ++ ++
Sbjct: 1539 QRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERE 1598
Query: 109 FED---EKKQLIRDNDQAIKVLQ-------------DELENRSNQVRCAE------KKLQ 146
E + + +R QA +V Q +E E + + AE ++L
Sbjct: 1599 LERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELA 1658
Query: 147 HKELESQEQIT-------------YIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFL 193
+ELE Q Q+ IR ET+ RQ LE+ ++ L+ +
Sbjct: 1659 EQELEKQRQLAEGTAQQRLAAEQELIRLRAETE----QGEQQRQLLEEELARLQREAAAA 1714
Query: 194 QKRASILQEEL 204
++ L+ EL
Sbjct: 1715 TQKRQELEAEL 1725
Score = 33.5 bits (75), Expect = 0.14
Identities = 39/174 (22%), Positives = 81/174 (46%), Gaps = 18/174 (10%)
Query: 48 SNLKEKKANSKLKQIEKEYTQKLAKSS----QIIAELQTTISSLKEENSQQQLAAERRLQ 103
+ L+E+ +Q E E ++ A+ Q+ A + EE +QQ+ A+ +
Sbjct: 1572 AQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAE 1631
Query: 104 DVRQKFEDEKKQLIRDNDQAIK---VLQDELENR-------SNQVRCAEKKL--QHKELE 151
+++ E E ++ + +QA++ + + ELE + + Q AE++L E E
Sbjct: 1632 KQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETE 1691
Query: 152 SQEQITYIRQEYETKLKGLMPASL--RQELEDTISSLKSQVNFLQKRASILQEE 203
EQ + +E +L+ A+ RQELE ++ +++++ L + +EE
Sbjct: 1692 QGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEE 1745
Score = 32.7 bits (73), Expect = 0.23
Identities = 36/153 (23%), Positives = 71/153 (46%), Gaps = 13/153 (8%)
Query: 60 KQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQ-DVRQ----KFEDEKK 114
KQ+ E+ ++L +I+ +LQ +E+ +Q A+ LQ DVR K
Sbjct: 350 KQLRSEF-ERLECLQRIVTKLQMEAGLCEEQLNQ----ADALLQSDVRLLAAGKVPQRAG 404
Query: 115 QLIRDNDQA---IKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLM 171
++ RD D+A I++L ++++ + +++ + E++ IR EY +LK +
Sbjct: 405 EVERDLDKADSMIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGV 464
Query: 172 PASLRQELEDTISSLKSQVNFLQKRASILQEEL 204
A Q + T+ S++ + LQ+ L
Sbjct: 465 AAPATQVAQVTLQSVQRRPELEDSTLRYLQDLL 497
Score = 31.2 bits (69), Expect = 0.67
Identities = 37/174 (21%), Positives = 73/174 (41%), Gaps = 28/174 (16%)
Query: 19 RLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEK-KANSKLKQIEKEYTQKLAKSSQII 77
RL E + E +L+ R +++ + K +A + K++++ +++ + +
Sbjct: 1317 RLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAA 1376
Query: 78 AELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQA----------IKVL 127
+ Q S++EE LQ +RQ E E + R + A I+V+
Sbjct: 1377 VDAQQQKRSIQEE-----------LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVV 1425
Query: 128 QDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELED 181
+ +LE Q AE +LQ ++E RQ E + LR++++D
Sbjct: 1426 RLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAER------LRRQVQD 1473
Score = 29.6 bits (65), Expect = 2.0
Identities = 37/188 (19%), Positives = 82/188 (43%), Gaps = 15/188 (7%)
Query: 21 IEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAEL 80
++M E + + E LRD + ++ K+KQ+ +E +L+ ++Q A L
Sbjct: 2203 VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE-AARLSVAAQEAARL 2261
Query: 81 QTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQVRC 140
+ +E+ +QQ+ AE+ L++ Q ++ + ++LQ + E Q R
Sbjct: 2262 RQLA---EEDLAQQRALAEKMLKEKMQAVQEATRL-----KAEAELLQQQKELAQEQAR- 2312
Query: 141 AEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASIL 200
+LQ + + +Q+ Q ++ L+ L E+ LK +V + + +
Sbjct: 2313 ---RLQEDKEQMAQQLAEETQGFQRTLEAERQRQL--EMSAEAERLKLRVAEMSRAQARA 2367
Query: 201 QEELTTYQ 208
+E+ ++
Sbjct: 2368 EEDAQRFR 2375
Score = 28.5 bits (62), Expect = 4.4
Identities = 28/155 (18%), Positives = 67/155 (43%), Gaps = 19/155 (12%)
Query: 11 SAKENQALRLIEMREENGNVPKTEQAGSLKP-LRDTGKSNLKEKKANSKLKQIEKEYTQK 69
+A+E + R E R + + E A K L + + K ++A ++ E+E ++
Sbjct: 1944 AAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQ 2003
Query: 70 LAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQD 129
L L +E +Q++L AE + + ++++ Q +Q++ D
Sbjct: 2004 L---------------QLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVL---D 2045
Query: 130 ELENRSNQVRCAEKKLQHKELESQEQITYIRQEYE 164
+L + R A ++ + ++++ + R++ E
Sbjct: 2046 QLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVE 2080
Score = 28.1 bits (61), Expect = 5.7
Identities = 16/51 (31%), Positives = 27/51 (52%)
Query: 66 YTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQL 116
Y Q + + +LQ +L+ + S + A RL+D+ Q +DEK+QL
Sbjct: 692 YFQFFSDVREAEGQLQKLQEALRRKYSCDRSATVTRLEDLLQDAQDEKEQL 742
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 47.8 bits (112), Expect = 7e-06
Identities = 38/165 (23%), Positives = 76/165 (46%), Gaps = 6/165 (3%)
Query: 3 ASLSLDHPSAKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQI 62
A L+ K Q +L++++ E + EQ L+ + +S L EK + L Q
Sbjct: 2588 AIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQL--LQETQALQQSFLSEKDS---LLQR 2642
Query: 63 EKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQ 122
E+ Q+ AK Q+ + L+EE +QQ E+ Q + E+ +++ + ++
Sbjct: 2643 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQ-HEAEE 2701
Query: 123 AIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKL 167
++ Q+EL+ Q R E+ L + +EQ+ + +++ L
Sbjct: 2702 GVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL 2746
Score = 45.1 bits (105), Expect = 4e-05
Identities = 50/211 (23%), Positives = 90/211 (42%), Gaps = 27/211 (12%)
Query: 11 SAKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEK----------KANSKLK 60
S +A RL ++ EE+ L R + LKEK KA ++L
Sbjct: 2421 SVAAQEAARLRQLAEED-----------LAQQRALAEKMLKEKMQAVQEATRLKAEAELL 2469
Query: 61 QIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDN 120
Q +KE Q+ A+ Q E + + + Q+ L AER+ Q + K + +
Sbjct: 2470 QQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEM 2529
Query: 121 DQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELE 180
+A +++ + Q +KL EL +QE++T ++ +++ + L
Sbjct: 2530 SRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQ---TLEIQRQQSDHDAERLR 2586
Query: 181 DTISSLKSQVNFLQKRASILQ---EELTTYQ 208
+ I+ L+ + LQ+ A +LQ EE+ T Q
Sbjct: 2587 EAIAELEREKEKLQQEAKLLQLKSEEMQTVQ 2617
Score = 44.7 bits (104), Expect = 6e-05
Identities = 50/187 (26%), Positives = 79/187 (42%), Gaps = 27/187 (14%)
Query: 3 ASLSLDHPSAKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQI 62
A L+ K N+ALRL EE QA + K + + + KA + +
Sbjct: 1764 AERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ 1823
Query: 63 EKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQ 122
+ Q+L K Q L E +QQ+LAAE+ L +R + E E+ +Q
Sbjct: 1824 RELAEQELEKQRQ-----------LAEGTAQQRLAAEQEL--IRLRAETEQ------GEQ 1864
Query: 123 AIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDT 182
++L++EL + A +K Q E E + +R E E L+ + R E E
Sbjct: 1865 QRQLLEEELARLQREAAAATQKRQELEAE----LAKVRAEMEV----LLASKARAEEESR 1916
Query: 183 ISSLKSQ 189
+S KS+
Sbjct: 1917 STSEKSK 1923
Score = 40.4 bits (93), Expect = 0.001
Identities = 43/170 (25%), Positives = 83/170 (48%), Gaps = 15/170 (8%)
Query: 43 RDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRL 102
R+ +S + ++A +LKQ +E Q A++ +L+ +Q + AA R+
Sbjct: 2239 REAAQSRRQVEEAE-RLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2297
Query: 103 QDVRQKFEDEKK---QLIRDN---DQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQI 156
Q + E KK Q +R +Q + L+ +LE +Q +++LQ + E+ E
Sbjct: 2298 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2357
Query: 157 TYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASILQEELTT 206
R + E +L S+R ++E+ +S LK+++ + RA IL+++ T
Sbjct: 2358 RQ-RSQVEEEL-----FSVRVQMEE-LSKLKARIE-AENRALILRDKDNT 2399
Score = 37.0 bits (84), Expect = 0.012
Identities = 41/190 (21%), Positives = 85/190 (44%), Gaps = 19/190 (10%)
Query: 39 LKPLRDTGKSNLKEKKANSKLKQ---IEKEYTQKLAKSSQIIAELQTTISSLKEEN--SQ 93
L+P+ K + + S +++ + Y++ +SQ I + T+ ++EE ++
Sbjct: 1430 LEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAE 1489
Query: 94 QQLAAER-RLQDVRQKFEDEKKQLIRDNDQA-------IKVLQDELENRSNQVRCAEKKL 145
QQ A ER RL +V E +++QL + QA K LQ ++ + A
Sbjct: 1490 QQRAEERERLAEVEAALE-KQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDA 1548
Query: 146 QHKELESQEQITYIRQEYETKLKGLMPAS-----LRQELEDTISSLKSQVNFLQKRASIL 200
Q ++ QE++ +RQ E +++ + R +E+ I ++ Q+ +++
Sbjct: 1549 QQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGA 1608
Query: 201 QEELTTYQGR 210
+ EL + R
Sbjct: 1609 EGELQALRAR 1618
Score = 33.5 bits (75), Expect = 0.14
Identities = 42/191 (21%), Positives = 80/191 (41%), Gaps = 42/191 (21%)
Query: 52 EKKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEE---NSQQQLAAERRLQDVRQK 108
++ A ++L+ + +K A+ + + E ++ L+EE +QQQ AER ++ ++
Sbjct: 1708 QRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERE 1767
Query: 109 FED---EKKQLIRDNDQAIKVLQ-------------DELENRSNQVRCAE------KKLQ 146
E + + +R QA +V Q +E E + + AE ++L
Sbjct: 1768 LERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELA 1827
Query: 147 HKELESQEQIT-------------YIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFL 193
+ELE Q Q+ IR ET+ RQ LE+ ++ L+ +
Sbjct: 1828 EQELEKQRQLAEGTAQQRLAAEQELIRLRAETE----QGEQQRQLLEEELARLQREAAAA 1883
Query: 194 QKRASILQEEL 204
++ L+ EL
Sbjct: 1884 TQKRQELEAEL 1894
Score = 33.5 bits (75), Expect = 0.14
Identities = 39/174 (22%), Positives = 81/174 (46%), Gaps = 18/174 (10%)
Query: 48 SNLKEKKANSKLKQIEKEYTQKLAKSS----QIIAELQTTISSLKEENSQQQLAAERRLQ 103
+ L+E+ +Q E E ++ A+ Q+ A + EE +QQ+ A+ +
Sbjct: 1741 AQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAE 1800
Query: 104 DVRQKFEDEKKQLIRDNDQAIK---VLQDELENR-------SNQVRCAEKKL--QHKELE 151
+++ E E ++ + +QA++ + + ELE + + Q AE++L E E
Sbjct: 1801 KQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETE 1860
Query: 152 SQEQITYIRQEYETKLKGLMPASL--RQELEDTISSLKSQVNFLQKRASILQEE 203
EQ + +E +L+ A+ RQELE ++ +++++ L + +EE
Sbjct: 1861 QGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEE 1914
Score = 32.7 bits (73), Expect = 0.23
Identities = 36/153 (23%), Positives = 71/153 (46%), Gaps = 13/153 (8%)
Query: 60 KQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQ-DVRQ----KFEDEKK 114
KQ+ E+ ++L +I+ +LQ +E+ +Q A+ LQ DVR K
Sbjct: 519 KQLRSEF-ERLECLQRIVTKLQMEAGLCEEQLNQ----ADALLQSDVRLLAAGKVPQRAG 573
Query: 115 QLIRDNDQA---IKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLM 171
++ RD D+A I++L ++++ + +++ + E++ IR EY +LK +
Sbjct: 574 EVERDLDKADSMIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGV 633
Query: 172 PASLRQELEDTISSLKSQVNFLQKRASILQEEL 204
A Q + T+ S++ + LQ+ L
Sbjct: 634 AAPATQVAQVTLQSVQRRPELEDSTLRYLQDLL 666
Score = 31.2 bits (69), Expect = 0.67
Identities = 37/174 (21%), Positives = 73/174 (41%), Gaps = 28/174 (16%)
Query: 19 RLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEK-KANSKLKQIEKEYTQKLAKSSQII 77
RL E + E +L+ R +++ + K +A + K++++ +++ + +
Sbjct: 1486 RLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAA 1545
Query: 78 AELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQA----------IKVL 127
+ Q S++EE LQ +RQ E E + R + A I+V+
Sbjct: 1546 VDAQQQKRSIQEE-----------LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVV 1594
Query: 128 QDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELED 181
+ +LE Q AE +LQ ++E RQ E + LR++++D
Sbjct: 1595 RLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAER------LRRQVQD 1642
Score = 29.6 bits (65), Expect = 2.0
Identities = 37/188 (19%), Positives = 82/188 (43%), Gaps = 15/188 (7%)
Query: 21 IEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAEL 80
++M E + + E LRD + ++ K+KQ+ +E +L+ ++Q A L
Sbjct: 2372 VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE-AARLSVAAQEAARL 2430
Query: 81 QTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQVRC 140
+ +E+ +QQ+ AE+ L++ Q ++ + ++LQ + E Q R
Sbjct: 2431 RQLA---EEDLAQQRALAEKMLKEKMQAVQEATRL-----KAEAELLQQQKELAQEQAR- 2481
Query: 141 AEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASIL 200
+LQ + + +Q+ Q ++ L+ L E+ LK +V + + +
Sbjct: 2482 ---RLQEDKEQMAQQLAEETQGFQRTLEAERQRQL--EMSAEAERLKLRVAEMSRAQARA 2536
Query: 201 QEELTTYQ 208
+E+ ++
Sbjct: 2537 EEDAQRFR 2544
Score = 28.5 bits (62), Expect = 4.4
Identities = 28/155 (18%), Positives = 67/155 (43%), Gaps = 19/155 (12%)
Query: 11 SAKENQALRLIEMREENGNVPKTEQAGSLKP-LRDTGKSNLKEKKANSKLKQIEKEYTQK 69
+A+E + R E R + + E A K L + + K ++A ++ E+E ++
Sbjct: 2113 AAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQ 2172
Query: 70 LAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQD 129
L L +E +Q++L AE + + ++++ Q +Q++ D
Sbjct: 2173 L---------------QLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVL---D 2214
Query: 130 ELENRSNQVRCAEKKLQHKELESQEQITYIRQEYE 164
+L + R A ++ + ++++ + R++ E
Sbjct: 2215 QLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVE 2249
Score = 28.1 bits (61), Expect = 5.7
Identities = 16/51 (31%), Positives = 27/51 (52%)
Query: 66 YTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQL 116
Y Q + + +LQ +L+ + S + A RL+D+ Q +DEK+QL
Sbjct: 861 YFQFFSDVREAEGQLQKLQEALRRKYSCDRSATVTRLEDLLQDAQDEKEQL 911
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 47.8 bits (112), Expect = 7e-06
Identities = 38/165 (23%), Positives = 76/165 (46%), Gaps = 6/165 (3%)
Query: 3 ASLSLDHPSAKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQI 62
A L+ K Q +L++++ E + EQ L+ + +S L EK + L Q
Sbjct: 2429 AIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQL--LQETQALQQSFLSEKDS---LLQR 2483
Query: 63 EKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQ 122
E+ Q+ AK Q+ + L+EE +QQ E+ Q + E+ +++ + ++
Sbjct: 2484 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQ-HEAEE 2542
Query: 123 AIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKL 167
++ Q+EL+ Q R E+ L + +EQ+ + +++ L
Sbjct: 2543 GVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL 2587
Score = 45.1 bits (105), Expect = 4e-05
Identities = 50/211 (23%), Positives = 90/211 (42%), Gaps = 27/211 (12%)
Query: 11 SAKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEK----------KANSKLK 60
S +A RL ++ EE+ L R + LKEK KA ++L
Sbjct: 2262 SVAAQEAARLRQLAEED-----------LAQQRALAEKMLKEKMQAVQEATRLKAEAELL 2310
Query: 61 QIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDN 120
Q +KE Q+ A+ Q E + + + Q+ L AER+ Q + K + +
Sbjct: 2311 QQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEM 2370
Query: 121 DQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELE 180
+A +++ + Q +KL EL +QE++T ++ +++ + L
Sbjct: 2371 SRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQ---TLEIQRQQSDHDAERLR 2427
Query: 181 DTISSLKSQVNFLQKRASILQ---EELTTYQ 208
+ I+ L+ + LQ+ A +LQ EE+ T Q
Sbjct: 2428 EAIAELEREKEKLQQEAKLLQLKSEEMQTVQ 2458
Score = 44.7 bits (104), Expect = 6e-05
Identities = 50/187 (26%), Positives = 79/187 (42%), Gaps = 27/187 (14%)
Query: 3 ASLSLDHPSAKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQI 62
A L+ K N+ALRL EE QA + K + + + KA + +
Sbjct: 1605 AERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ 1664
Query: 63 EKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQ 122
+ Q+L K Q L E +QQ+LAAE+ L +R + E E+ +Q
Sbjct: 1665 RELAEQELEKQRQ-----------LAEGTAQQRLAAEQEL--IRLRAETEQ------GEQ 1705
Query: 123 AIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDT 182
++L++EL + A +K Q E E + +R E E L+ + R E E
Sbjct: 1706 QRQLLEEELARLQREAAAATQKRQELEAE----LAKVRAEMEV----LLASKARAEEESR 1757
Query: 183 ISSLKSQ 189
+S KS+
Sbjct: 1758 STSEKSK 1764
Score = 40.4 bits (93), Expect = 0.001
Identities = 43/170 (25%), Positives = 83/170 (48%), Gaps = 15/170 (8%)
Query: 43 RDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRL 102
R+ +S + ++A +LKQ +E Q A++ +L+ +Q + AA R+
Sbjct: 2080 REAAQSRRQVEEAE-RLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2138
Query: 103 QDVRQKFEDEKK---QLIRDN---DQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQI 156
Q + E KK Q +R +Q + L+ +LE +Q +++LQ + E+ E
Sbjct: 2139 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2198
Query: 157 TYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASILQEELTT 206
R + E +L S+R ++E+ +S LK+++ + RA IL+++ T
Sbjct: 2199 RQ-RSQVEEEL-----FSVRVQMEE-LSKLKARIE-AENRALILRDKDNT 2240
Score = 37.0 bits (84), Expect = 0.012
Identities = 41/190 (21%), Positives = 85/190 (44%), Gaps = 19/190 (10%)
Query: 39 LKPLRDTGKSNLKEKKANSKLKQ---IEKEYTQKLAKSSQIIAELQTTISSLKEEN--SQ 93
L+P+ K + + S +++ + Y++ +SQ I + T+ ++EE ++
Sbjct: 1271 LEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAE 1330
Query: 94 QQLAAER-RLQDVRQKFEDEKKQLIRDNDQA-------IKVLQDELENRSNQVRCAEKKL 145
QQ A ER RL +V E +++QL + QA K LQ ++ + A
Sbjct: 1331 QQRAEERERLAEVEAALE-KQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDA 1389
Query: 146 QHKELESQEQITYIRQEYETKLKGLMPAS-----LRQELEDTISSLKSQVNFLQKRASIL 200
Q ++ QE++ +RQ E +++ + R +E+ I ++ Q+ +++
Sbjct: 1390 QQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGA 1449
Query: 201 QEELTTYQGR 210
+ EL + R
Sbjct: 1450 EGELQALRAR 1459
Score = 33.5 bits (75), Expect = 0.14
Identities = 42/191 (21%), Positives = 80/191 (41%), Gaps = 42/191 (21%)
Query: 52 EKKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEE---NSQQQLAAERRLQDVRQK 108
++ A ++L+ + +K A+ + + E ++ L+EE +QQQ AER ++ ++
Sbjct: 1549 QRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERE 1608
Query: 109 FED---EKKQLIRDNDQAIKVLQ-------------DELENRSNQVRCAE------KKLQ 146
E + + +R QA +V Q +E E + + AE ++L
Sbjct: 1609 LERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELA 1668
Query: 147 HKELESQEQIT-------------YIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFL 193
+ELE Q Q+ IR ET+ RQ LE+ ++ L+ +
Sbjct: 1669 EQELEKQRQLAEGTAQQRLAAEQELIRLRAETE----QGEQQRQLLEEELARLQREAAAA 1724
Query: 194 QKRASILQEEL 204
++ L+ EL
Sbjct: 1725 TQKRQELEAEL 1735
Score = 33.5 bits (75), Expect = 0.14
Identities = 39/174 (22%), Positives = 81/174 (46%), Gaps = 18/174 (10%)
Query: 48 SNLKEKKANSKLKQIEKEYTQKLAKSS----QIIAELQTTISSLKEENSQQQLAAERRLQ 103
+ L+E+ +Q E E ++ A+ Q+ A + EE +QQ+ A+ +
Sbjct: 1582 AQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAE 1641
Query: 104 DVRQKFEDEKKQLIRDNDQAIK---VLQDELENR-------SNQVRCAEKKL--QHKELE 151
+++ E E ++ + +QA++ + + ELE + + Q AE++L E E
Sbjct: 1642 KQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETE 1701
Query: 152 SQEQITYIRQEYETKLKGLMPASL--RQELEDTISSLKSQVNFLQKRASILQEE 203
EQ + +E +L+ A+ RQELE ++ +++++ L + +EE
Sbjct: 1702 QGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEE 1755
Score = 32.7 bits (73), Expect = 0.23
Identities = 36/153 (23%), Positives = 71/153 (46%), Gaps = 13/153 (8%)
Query: 60 KQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQ-DVRQ----KFEDEKK 114
KQ+ E+ ++L +I+ +LQ +E+ +Q A+ LQ DVR K
Sbjct: 360 KQLRSEF-ERLECLQRIVTKLQMEAGLCEEQLNQ----ADALLQSDVRLLAAGKVPQRAG 414
Query: 115 QLIRDNDQA---IKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLM 171
++ RD D+A I++L ++++ + +++ + E++ IR EY +LK +
Sbjct: 415 EVERDLDKADSMIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGV 474
Query: 172 PASLRQELEDTISSLKSQVNFLQKRASILQEEL 204
A Q + T+ S++ + LQ+ L
Sbjct: 475 AAPATQVAQVTLQSVQRRPELEDSTLRYLQDLL 507
Score = 31.2 bits (69), Expect = 0.67
Identities = 37/174 (21%), Positives = 73/174 (41%), Gaps = 28/174 (16%)
Query: 19 RLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEK-KANSKLKQIEKEYTQKLAKSSQII 77
RL E + E +L+ R +++ + K +A + K++++ +++ + +
Sbjct: 1327 RLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAA 1386
Query: 78 AELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQA----------IKVL 127
+ Q S++EE LQ +RQ E E + R + A I+V+
Sbjct: 1387 VDAQQQKRSIQEE-----------LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVV 1435
Query: 128 QDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELED 181
+ +LE Q AE +LQ ++E RQ E + LR++++D
Sbjct: 1436 RLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAER------LRRQVQD 1483
Score = 29.6 bits (65), Expect = 2.0
Identities = 37/188 (19%), Positives = 82/188 (43%), Gaps = 15/188 (7%)
Query: 21 IEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAEL 80
++M E + + E LRD + ++ K+KQ+ +E +L+ ++Q A L
Sbjct: 2213 VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE-AARLSVAAQEAARL 2271
Query: 81 QTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQVRC 140
+ +E+ +QQ+ AE+ L++ Q ++ + ++LQ + E Q R
Sbjct: 2272 RQLA---EEDLAQQRALAEKMLKEKMQAVQEATRL-----KAEAELLQQQKELAQEQAR- 2322
Query: 141 AEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASIL 200
+LQ + + +Q+ Q ++ L+ L E+ LK +V + + +
Sbjct: 2323 ---RLQEDKEQMAQQLAEETQGFQRTLEAERQRQL--EMSAEAERLKLRVAEMSRAQARA 2377
Query: 201 QEELTTYQ 208
+E+ ++
Sbjct: 2378 EEDAQRFR 2385
Score = 28.5 bits (62), Expect = 4.4
Identities = 28/155 (18%), Positives = 67/155 (43%), Gaps = 19/155 (12%)
Query: 11 SAKENQALRLIEMREENGNVPKTEQAGSLKP-LRDTGKSNLKEKKANSKLKQIEKEYTQK 69
+A+E + R E R + + E A K L + + K ++A ++ E+E ++
Sbjct: 1954 AAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQ 2013
Query: 70 LAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQD 129
L L +E +Q++L AE + + ++++ Q +Q++ D
Sbjct: 2014 L---------------QLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVL---D 2055
Query: 130 ELENRSNQVRCAEKKLQHKELESQEQITYIRQEYE 164
+L + R A ++ + ++++ + R++ E
Sbjct: 2056 QLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVE 2090
Score = 28.1 bits (61), Expect = 5.7
Identities = 16/51 (31%), Positives = 27/51 (52%)
Query: 66 YTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQL 116
Y Q + + +LQ +L+ + S + A RL+D+ Q +DEK+QL
Sbjct: 702 YFQFFSDVREAEGQLQKLQEALRRKYSCDRSATVTRLEDLLQDAQDEKEQL 752
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 47.8 bits (112), Expect = 7e-06
Identities = 38/165 (23%), Positives = 76/165 (46%), Gaps = 6/165 (3%)
Query: 3 ASLSLDHPSAKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQI 62
A L+ K Q +L++++ E + EQ L+ + +S L EK + L Q
Sbjct: 2437 AIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQL--LQETQALQQSFLSEKDS---LLQR 2491
Query: 63 EKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQ 122
E+ Q+ AK Q+ + L+EE +QQ E+ Q + E+ +++ + ++
Sbjct: 2492 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQ-HEAEE 2550
Query: 123 AIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKL 167
++ Q+EL+ Q R E+ L + +EQ+ + +++ L
Sbjct: 2551 GVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL 2595
Score = 45.1 bits (105), Expect = 4e-05
Identities = 50/211 (23%), Positives = 90/211 (42%), Gaps = 27/211 (12%)
Query: 11 SAKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEK----------KANSKLK 60
S +A RL ++ EE+ L R + LKEK KA ++L
Sbjct: 2270 SVAAQEAARLRQLAEED-----------LAQQRALAEKMLKEKMQAVQEATRLKAEAELL 2318
Query: 61 QIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDN 120
Q +KE Q+ A+ Q E + + + Q+ L AER+ Q + K + +
Sbjct: 2319 QQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEM 2378
Query: 121 DQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELE 180
+A +++ + Q +KL EL +QE++T ++ +++ + L
Sbjct: 2379 SRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQ---TLEIQRQQSDHDAERLR 2435
Query: 181 DTISSLKSQVNFLQKRASILQ---EELTTYQ 208
+ I+ L+ + LQ+ A +LQ EE+ T Q
Sbjct: 2436 EAIAELEREKEKLQQEAKLLQLKSEEMQTVQ 2466
Score = 44.7 bits (104), Expect = 6e-05
Identities = 50/187 (26%), Positives = 79/187 (42%), Gaps = 27/187 (14%)
Query: 3 ASLSLDHPSAKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQI 62
A L+ K N+ALRL EE QA + K + + + KA + +
Sbjct: 1613 AERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ 1672
Query: 63 EKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQ 122
+ Q+L K Q L E +QQ+LAAE+ L +R + E E+ +Q
Sbjct: 1673 RELAEQELEKQRQ-----------LAEGTAQQRLAAEQEL--IRLRAETEQ------GEQ 1713
Query: 123 AIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDT 182
++L++EL + A +K Q E E + +R E E L+ + R E E
Sbjct: 1714 QRQLLEEELARLQREAAAATQKRQELEAE----LAKVRAEMEV----LLASKARAEEESR 1765
Query: 183 ISSLKSQ 189
+S KS+
Sbjct: 1766 STSEKSK 1772
Score = 40.4 bits (93), Expect = 0.001
Identities = 43/170 (25%), Positives = 83/170 (48%), Gaps = 15/170 (8%)
Query: 43 RDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRL 102
R+ +S + ++A +LKQ +E Q A++ +L+ +Q + AA R+
Sbjct: 2088 REAAQSRRQVEEAE-RLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2146
Query: 103 QDVRQKFEDEKK---QLIRDN---DQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQI 156
Q + E KK Q +R +Q + L+ +LE +Q +++LQ + E+ E
Sbjct: 2147 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2206
Query: 157 TYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASILQEELTT 206
R + E +L S+R ++E+ +S LK+++ + RA IL+++ T
Sbjct: 2207 RQ-RSQVEEEL-----FSVRVQMEE-LSKLKARIE-AENRALILRDKDNT 2248
Score = 37.0 bits (84), Expect = 0.012
Identities = 41/190 (21%), Positives = 85/190 (44%), Gaps = 19/190 (10%)
Query: 39 LKPLRDTGKSNLKEKKANSKLKQ---IEKEYTQKLAKSSQIIAELQTTISSLKEEN--SQ 93
L+P+ K + + S +++ + Y++ +SQ I + T+ ++EE ++
Sbjct: 1279 LEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAE 1338
Query: 94 QQLAAER-RLQDVRQKFEDEKKQLIRDNDQA-------IKVLQDELENRSNQVRCAEKKL 145
QQ A ER RL +V E +++QL + QA K LQ ++ + A
Sbjct: 1339 QQRAEERERLAEVEAALE-KQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDA 1397
Query: 146 QHKELESQEQITYIRQEYETKLKGLMPAS-----LRQELEDTISSLKSQVNFLQKRASIL 200
Q ++ QE++ +RQ E +++ + R +E+ I ++ Q+ +++
Sbjct: 1398 QQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGA 1457
Query: 201 QEELTTYQGR 210
+ EL + R
Sbjct: 1458 EGELQALRAR 1467
Score = 33.5 bits (75), Expect = 0.14
Identities = 42/191 (21%), Positives = 80/191 (41%), Gaps = 42/191 (21%)
Query: 52 EKKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEE---NSQQQLAAERRLQDVRQK 108
++ A ++L+ + +K A+ + + E ++ L+EE +QQQ AER ++ ++
Sbjct: 1557 QRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERE 1616
Query: 109 FED---EKKQLIRDNDQAIKVLQ-------------DELENRSNQVRCAE------KKLQ 146
E + + +R QA +V Q +E E + + AE ++L
Sbjct: 1617 LERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELA 1676
Query: 147 HKELESQEQIT-------------YIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFL 193
+ELE Q Q+ IR ET+ RQ LE+ ++ L+ +
Sbjct: 1677 EQELEKQRQLAEGTAQQRLAAEQELIRLRAETE----QGEQQRQLLEEELARLQREAAAA 1732
Query: 194 QKRASILQEEL 204
++ L+ EL
Sbjct: 1733 TQKRQELEAEL 1743
Score = 33.5 bits (75), Expect = 0.14
Identities = 39/174 (22%), Positives = 81/174 (46%), Gaps = 18/174 (10%)
Query: 48 SNLKEKKANSKLKQIEKEYTQKLAKSS----QIIAELQTTISSLKEENSQQQLAAERRLQ 103
+ L+E+ +Q E E ++ A+ Q+ A + EE +QQ+ A+ +
Sbjct: 1590 AQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAE 1649
Query: 104 DVRQKFEDEKKQLIRDNDQAIK---VLQDELENR-------SNQVRCAEKKL--QHKELE 151
+++ E E ++ + +QA++ + + ELE + + Q AE++L E E
Sbjct: 1650 KQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETE 1709
Query: 152 SQEQITYIRQEYETKLKGLMPASL--RQELEDTISSLKSQVNFLQKRASILQEE 203
EQ + +E +L+ A+ RQELE ++ +++++ L + +EE
Sbjct: 1710 QGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEE 1763
Score = 32.7 bits (73), Expect = 0.23
Identities = 36/153 (23%), Positives = 71/153 (46%), Gaps = 13/153 (8%)
Query: 60 KQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQ-DVRQ----KFEDEKK 114
KQ+ E+ ++L +I+ +LQ +E+ +Q A+ LQ DVR K
Sbjct: 368 KQLRSEF-ERLECLQRIVTKLQMEAGLCEEQLNQ----ADALLQSDVRLLAAGKVPQRAG 422
Query: 115 QLIRDNDQA---IKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLM 171
++ RD D+A I++L ++++ + +++ + E++ IR EY +LK +
Sbjct: 423 EVERDLDKADSMIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGV 482
Query: 172 PASLRQELEDTISSLKSQVNFLQKRASILQEEL 204
A Q + T+ S++ + LQ+ L
Sbjct: 483 AAPATQVAQVTLQSVQRRPELEDSTLRYLQDLL 515
Score = 31.2 bits (69), Expect = 0.67
Identities = 37/174 (21%), Positives = 73/174 (41%), Gaps = 28/174 (16%)
Query: 19 RLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEK-KANSKLKQIEKEYTQKLAKSSQII 77
RL E + E +L+ R +++ + K +A + K++++ +++ + +
Sbjct: 1335 RLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAA 1394
Query: 78 AELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQA----------IKVL 127
+ Q S++EE LQ +RQ E E + R + A I+V+
Sbjct: 1395 VDAQQQKRSIQEE-----------LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVV 1443
Query: 128 QDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELED 181
+ +LE Q AE +LQ ++E RQ E + LR++++D
Sbjct: 1444 RLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAER------LRRQVQD 1491
Score = 29.6 bits (65), Expect = 2.0
Identities = 37/188 (19%), Positives = 82/188 (43%), Gaps = 15/188 (7%)
Query: 21 IEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAEL 80
++M E + + E LRD + ++ K+KQ+ +E +L+ ++Q A L
Sbjct: 2221 VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE-AARLSVAAQEAARL 2279
Query: 81 QTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQVRC 140
+ +E+ +QQ+ AE+ L++ Q ++ + ++LQ + E Q R
Sbjct: 2280 RQLA---EEDLAQQRALAEKMLKEKMQAVQEATRL-----KAEAELLQQQKELAQEQAR- 2330
Query: 141 AEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASIL 200
+LQ + + +Q+ Q ++ L+ L E+ LK +V + + +
Sbjct: 2331 ---RLQEDKEQMAQQLAEETQGFQRTLEAERQRQL--EMSAEAERLKLRVAEMSRAQARA 2385
Query: 201 QEELTTYQ 208
+E+ ++
Sbjct: 2386 EEDAQRFR 2393
Score = 28.5 bits (62), Expect = 4.4
Identities = 28/155 (18%), Positives = 67/155 (43%), Gaps = 19/155 (12%)
Query: 11 SAKENQALRLIEMREENGNVPKTEQAGSLKP-LRDTGKSNLKEKKANSKLKQIEKEYTQK 69
+A+E + R E R + + E A K L + + K ++A ++ E+E ++
Sbjct: 1962 AAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQ 2021
Query: 70 LAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQD 129
L L +E +Q++L AE + + ++++ Q +Q++ D
Sbjct: 2022 L---------------QLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVL---D 2063
Query: 130 ELENRSNQVRCAEKKLQHKELESQEQITYIRQEYE 164
+L + R A ++ + ++++ + R++ E
Sbjct: 2064 QLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVE 2098
Score = 28.1 bits (61), Expect = 5.7
Identities = 16/51 (31%), Positives = 27/51 (52%)
Query: 66 YTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQL 116
Y Q + + +LQ +L+ + S + A RL+D+ Q +DEK+QL
Sbjct: 710 YFQFFSDVREAEGQLQKLQEALRRKYSCDRSATVTRLEDLLQDAQDEKEQL 760
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 47.8 bits (112), Expect = 7e-06
Identities = 38/165 (23%), Positives = 76/165 (46%), Gaps = 6/165 (3%)
Query: 3 ASLSLDHPSAKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQI 62
A L+ K Q +L++++ E + EQ L+ + +S L EK + L Q
Sbjct: 2478 AIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQL--LQETQALQQSFLSEKDS---LLQR 2532
Query: 63 EKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQ 122
E+ Q+ AK Q+ + L+EE +QQ E+ Q + E+ +++ + ++
Sbjct: 2533 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQ-HEAEE 2591
Query: 123 AIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKL 167
++ Q+EL+ Q R E+ L + +EQ+ + +++ L
Sbjct: 2592 GVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL 2636
Score = 45.1 bits (105), Expect = 4e-05
Identities = 50/211 (23%), Positives = 90/211 (42%), Gaps = 27/211 (12%)
Query: 11 SAKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEK----------KANSKLK 60
S +A RL ++ EE+ L R + LKEK KA ++L
Sbjct: 2311 SVAAQEAARLRQLAEED-----------LAQQRALAEKMLKEKMQAVQEATRLKAEAELL 2359
Query: 61 QIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDN 120
Q +KE Q+ A+ Q E + + + Q+ L AER+ Q + K + +
Sbjct: 2360 QQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEM 2419
Query: 121 DQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELE 180
+A +++ + Q +KL EL +QE++T ++ +++ + L
Sbjct: 2420 SRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQ---TLEIQRQQSDHDAERLR 2476
Query: 181 DTISSLKSQVNFLQKRASILQ---EELTTYQ 208
+ I+ L+ + LQ+ A +LQ EE+ T Q
Sbjct: 2477 EAIAELEREKEKLQQEAKLLQLKSEEMQTVQ 2507
Score = 44.7 bits (104), Expect = 6e-05
Identities = 50/187 (26%), Positives = 79/187 (42%), Gaps = 27/187 (14%)
Query: 3 ASLSLDHPSAKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQI 62
A L+ K N+ALRL EE QA + K + + + KA + +
Sbjct: 1654 AERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ 1713
Query: 63 EKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQ 122
+ Q+L K Q L E +QQ+LAAE+ L +R + E E+ +Q
Sbjct: 1714 RELAEQELEKQRQ-----------LAEGTAQQRLAAEQEL--IRLRAETEQ------GEQ 1754
Query: 123 AIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDT 182
++L++EL + A +K Q E E + +R E E L+ + R E E
Sbjct: 1755 QRQLLEEELARLQREAAAATQKRQELEAE----LAKVRAEMEV----LLASKARAEEESR 1806
Query: 183 ISSLKSQ 189
+S KS+
Sbjct: 1807 STSEKSK 1813
Score = 40.4 bits (93), Expect = 0.001
Identities = 43/170 (25%), Positives = 83/170 (48%), Gaps = 15/170 (8%)
Query: 43 RDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRL 102
R+ +S + ++A +LKQ +E Q A++ +L+ +Q + AA R+
Sbjct: 2129 REAAQSRRQVEEAE-RLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2187
Query: 103 QDVRQKFEDEKK---QLIRDN---DQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQI 156
Q + E KK Q +R +Q + L+ +LE +Q +++LQ + E+ E
Sbjct: 2188 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2247
Query: 157 TYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASILQEELTT 206
R + E +L S+R ++E+ +S LK+++ + RA IL+++ T
Sbjct: 2248 RQ-RSQVEEEL-----FSVRVQMEE-LSKLKARIE-AENRALILRDKDNT 2289
Score = 37.0 bits (84), Expect = 0.012
Identities = 41/190 (21%), Positives = 85/190 (44%), Gaps = 19/190 (10%)
Query: 39 LKPLRDTGKSNLKEKKANSKLKQ---IEKEYTQKLAKSSQIIAELQTTISSLKEEN--SQ 93
L+P+ K + + S +++ + Y++ +SQ I + T+ ++EE ++
Sbjct: 1320 LEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAE 1379
Query: 94 QQLAAER-RLQDVRQKFEDEKKQLIRDNDQA-------IKVLQDELENRSNQVRCAEKKL 145
QQ A ER RL +V E +++QL + QA K LQ ++ + A
Sbjct: 1380 QQRAEERERLAEVEAALE-KQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDA 1438
Query: 146 QHKELESQEQITYIRQEYETKLKGLMPAS-----LRQELEDTISSLKSQVNFLQKRASIL 200
Q ++ QE++ +RQ E +++ + R +E+ I ++ Q+ +++
Sbjct: 1439 QQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGA 1498
Query: 201 QEELTTYQGR 210
+ EL + R
Sbjct: 1499 EGELQALRAR 1508
Score = 33.5 bits (75), Expect = 0.14
Identities = 42/191 (21%), Positives = 80/191 (41%), Gaps = 42/191 (21%)
Query: 52 EKKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEE---NSQQQLAAERRLQDVRQK 108
++ A ++L+ + +K A+ + + E ++ L+EE +QQQ AER ++ ++
Sbjct: 1598 QRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERE 1657
Query: 109 FED---EKKQLIRDNDQAIKVLQ-------------DELENRSNQVRCAE------KKLQ 146
E + + +R QA +V Q +E E + + AE ++L
Sbjct: 1658 LERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELA 1717
Query: 147 HKELESQEQIT-------------YIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFL 193
+ELE Q Q+ IR ET+ RQ LE+ ++ L+ +
Sbjct: 1718 EQELEKQRQLAEGTAQQRLAAEQELIRLRAETE----QGEQQRQLLEEELARLQREAAAA 1773
Query: 194 QKRASILQEEL 204
++ L+ EL
Sbjct: 1774 TQKRQELEAEL 1784
Score = 33.5 bits (75), Expect = 0.14
Identities = 39/174 (22%), Positives = 81/174 (46%), Gaps = 18/174 (10%)
Query: 48 SNLKEKKANSKLKQIEKEYTQKLAKSS----QIIAELQTTISSLKEENSQQQLAAERRLQ 103
+ L+E+ +Q E E ++ A+ Q+ A + EE +QQ+ A+ +
Sbjct: 1631 AQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAE 1690
Query: 104 DVRQKFEDEKKQLIRDNDQAIK---VLQDELENR-------SNQVRCAEKKL--QHKELE 151
+++ E E ++ + +QA++ + + ELE + + Q AE++L E E
Sbjct: 1691 KQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETE 1750
Query: 152 SQEQITYIRQEYETKLKGLMPASL--RQELEDTISSLKSQVNFLQKRASILQEE 203
EQ + +E +L+ A+ RQELE ++ +++++ L + +EE
Sbjct: 1751 QGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEE 1804
Score = 32.7 bits (73), Expect = 0.23
Identities = 36/153 (23%), Positives = 71/153 (46%), Gaps = 13/153 (8%)
Query: 60 KQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQ-DVRQ----KFEDEKK 114
KQ+ E+ ++L +I+ +LQ +E+ +Q A+ LQ DVR K
Sbjct: 409 KQLRSEF-ERLECLQRIVTKLQMEAGLCEEQLNQ----ADALLQSDVRLLAAGKVPQRAG 463
Query: 115 QLIRDNDQA---IKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLM 171
++ RD D+A I++L ++++ + +++ + E++ IR EY +LK +
Sbjct: 464 EVERDLDKADSMIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGV 523
Query: 172 PASLRQELEDTISSLKSQVNFLQKRASILQEEL 204
A Q + T+ S++ + LQ+ L
Sbjct: 524 AAPATQVAQVTLQSVQRRPELEDSTLRYLQDLL 556
Score = 31.2 bits (69), Expect = 0.67
Identities = 37/174 (21%), Positives = 73/174 (41%), Gaps = 28/174 (16%)
Query: 19 RLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEK-KANSKLKQIEKEYTQKLAKSSQII 77
RL E + E +L+ R +++ + K +A + K++++ +++ + +
Sbjct: 1376 RLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAA 1435
Query: 78 AELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQA----------IKVL 127
+ Q S++EE LQ +RQ E E + R + A I+V+
Sbjct: 1436 VDAQQQKRSIQEE-----------LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVV 1484
Query: 128 QDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELED 181
+ +LE Q AE +LQ ++E RQ E + LR++++D
Sbjct: 1485 RLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAER------LRRQVQD 1532
Score = 29.6 bits (65), Expect = 2.0
Identities = 37/188 (19%), Positives = 82/188 (43%), Gaps = 15/188 (7%)
Query: 21 IEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAEL 80
++M E + + E LRD + ++ K+KQ+ +E +L+ ++Q A L
Sbjct: 2262 VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE-AARLSVAAQEAARL 2320
Query: 81 QTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQVRC 140
+ +E+ +QQ+ AE+ L++ Q ++ + ++LQ + E Q R
Sbjct: 2321 RQLA---EEDLAQQRALAEKMLKEKMQAVQEATRL-----KAEAELLQQQKELAQEQAR- 2371
Query: 141 AEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASIL 200
+LQ + + +Q+ Q ++ L+ L E+ LK +V + + +
Sbjct: 2372 ---RLQEDKEQMAQQLAEETQGFQRTLEAERQRQL--EMSAEAERLKLRVAEMSRAQARA 2426
Query: 201 QEELTTYQ 208
+E+ ++
Sbjct: 2427 EEDAQRFR 2434
Score = 28.5 bits (62), Expect = 4.4
Identities = 28/155 (18%), Positives = 67/155 (43%), Gaps = 19/155 (12%)
Query: 11 SAKENQALRLIEMREENGNVPKTEQAGSLKP-LRDTGKSNLKEKKANSKLKQIEKEYTQK 69
+A+E + R E R + + E A K L + + K ++A ++ E+E ++
Sbjct: 2003 AAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQ 2062
Query: 70 LAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQD 129
L L +E +Q++L AE + + ++++ Q +Q++ D
Sbjct: 2063 L---------------QLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVL---D 2104
Query: 130 ELENRSNQVRCAEKKLQHKELESQEQITYIRQEYE 164
+L + R A ++ + ++++ + R++ E
Sbjct: 2105 QLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVE 2139
Score = 28.1 bits (61), Expect = 5.7
Identities = 16/51 (31%), Positives = 27/51 (52%)
Query: 66 YTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQL 116
Y Q + + +LQ +L+ + S + A RL+D+ Q +DEK+QL
Sbjct: 751 YFQFFSDVREAEGQLQKLQEALRRKYSCDRSATVTRLEDLLQDAQDEKEQL 801
>gi|10864047 epidermal growth factor receptor pathway substrate
15-like 1 [Homo sapiens]
Length = 864
Score = 47.8 bits (112), Expect = 7e-06
Identities = 48/206 (23%), Positives = 94/206 (45%), Gaps = 34/206 (16%)
Query: 25 EENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAELQTTI 84
+ +G++ E G +K L D + + ++ L+Q +E + + + + + ELQ +
Sbjct: 370 DSSGSLGSGEFTG-VKELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDL 428
Query: 85 ----SSLKEENSQQQLAAER-------------RLQDVRQKFEDEKKQL------IRDND 121
SSL+E +Q+Q A +R L DVRQK +DE + + I+ +
Sbjct: 429 DRETSSLQELEAQKQDAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQE 488
Query: 122 QAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELED 181
+K +D+L N+ + +LQ +E + ++ I R + ET +K L + +D
Sbjct: 489 SDLKSQEDDL----NRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSL------KSTQD 538
Query: 182 TISSLKSQVNFLQKRASILQEELTTY 207
I+ +S+++ L + L Y
Sbjct: 539 EINQARSKLSQLHESRQEAHRSLEQY 564
>gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens]
Length = 841
Score = 47.8 bits (112), Expect = 7e-06
Identities = 51/207 (24%), Positives = 99/207 (47%), Gaps = 38/207 (18%)
Query: 13 KENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQIEKEYTQKLAK 72
+E A+RL +E G + E+ L+ L + K +E++ ++++ EK T++L
Sbjct: 449 EELGAVRLRHEKEVLGVRARYER--ELRELHEDKKR--QEEELRGQIRE-EKARTRELET 503
Query: 73 SSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELE 132
Q + ELQ + S+ ERRL++ + + ++++ Q+E
Sbjct: 504 LQQTVEELQAQVHSMDGAKGW----FERRLKEAEESLQQQQQE------------QEEAL 547
Query: 133 NRSNQVRCAEKKLQHKELES-QEQITYIRQEYETKLKGLMPASLRQELEDTISS------ 185
+ + AE K + +EL+ ++Q+ ++E + LK + +SL+QE++DT+
Sbjct: 548 KQCREQHAAELKGKEEELQDVRDQLEQAQEERDCHLKTI--SSLKQEVKDTVDGQRILEK 605
Query: 186 --------LKSQVNFLQKRASILQEEL 204
LK Q++ +KRA LQE L
Sbjct: 606 KGSAALKDLKRQLHLERKRADKLQERL 632
Score = 43.5 bits (101), Expect = 1e-04
Identities = 54/215 (25%), Positives = 93/215 (43%), Gaps = 43/215 (20%)
Query: 14 ENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQIEKEYTQKLAKS 73
EN ALR E KT++ L+ + TG + ++L+Q + EY + +
Sbjct: 334 ENNALRTSLAALEQIQTAKTQELNMLRE-QTTGLA--------AELQQQQAEYEDLMGQK 384
Query: 74 SQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIK------VL 127
+ ++LQ + L A RL + Q+ EK+QL ++ +A K +
Sbjct: 385 DDLNSQLQ------------ESLRANSRLLEQLQEIGQEKEQLTQELQEARKSAEKRKAM 432
Query: 128 QDELENRSNQVRCAEKKLQHKE------LESQEQITYIRQEYETKLKGLMPASLRQ--EL 179
DEL + Q +K QHKE L ++++ +R YE +L+ L RQ EL
Sbjct: 433 LDELAMETLQ-----EKSQHKEELGAVRLRHEKEVLGVRARYERELRELHEDKKRQEEEL 487
Query: 180 EDTISSLKS---QVNFLQKRASILQEELTTYQGRR 211
I K+ ++ LQ+ LQ ++ + G +
Sbjct: 488 RGQIREEKARTRELETLQQTVEELQAQVHSMDGAK 522
Score = 29.3 bits (64), Expect = 2.6
Identities = 28/132 (21%), Positives = 59/132 (44%), Gaps = 8/132 (6%)
Query: 59 LKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFED------E 112
L ++E ++ + + + +LQ SS + E S+ Q + + +++K E E
Sbjct: 189 LAEVELKWEMEKEEKRLLWEQLQGLESSKQAETSRLQEELAKLSEKLKKKQESFCRLQTE 248
Query: 113 KKQLIRDNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMP 172
K+ L D+ I+ LQ E +KLQ + + + + +R + + + L
Sbjct: 249 KETLFNDSRNKIEELQQRKEADHKAQLARTQKLQQELEAANQSLAELRDQRQG--ERLEH 306
Query: 173 ASLRQELEDTIS 184
A+ + L+D +S
Sbjct: 307 AAALRALQDQVS 318
Score = 28.1 bits (61), Expect = 5.7
Identities = 42/183 (22%), Positives = 77/183 (42%), Gaps = 30/183 (16%)
Query: 49 NLKEKKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQ------LAAERRL 102
N K ++ E ++ +LA++ ++ EL+ SL E Q+Q AA R L
Sbjct: 254 NDSRNKIEELQQRKEADHKAQLARTQKLQQELEAANQSLAELRDQRQGERLEHAAALRAL 313
Query: 103 QD-VRQKFEDEKKQL---------IRDNDQAIKVLQ----DELENRSNQVRCAEKKLQHK 148
QD V + D ++Q+ +R + A++ +Q EL Q +LQ +
Sbjct: 314 QDQVSIQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQELNMLREQTTGLAAELQQQ 373
Query: 149 ELESQEQITYIRQEYETKLKGLMPASLR---------QELEDTISSLKSQVNFLQKRASI 199
+ E E + + + ++L+ + A+ R QE E L+ +KR ++
Sbjct: 374 QAE-YEDLMGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQELQEARKSAEKRKAM 432
Query: 200 LQE 202
L E
Sbjct: 433 LDE 435
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 47.0 bits (110), Expect = 1e-05
Identities = 37/160 (23%), Positives = 81/160 (50%), Gaps = 14/160 (8%)
Query: 47 KSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVR 106
K+ +++KA ++LK++E++++Q + + + +LQ ++ +L AE VR
Sbjct: 863 KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQ----------AETELYAEAEEMRVR 912
Query: 107 QKFEDEKKQLIRDNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIR-QEYET 165
KKQ + + ++ +E E+R Q++ KK+ + L+ +EQ+ +
Sbjct: 913 LA---AKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 969
Query: 166 KLKGLMPASLRQELEDTISSLKSQVNFLQKRASILQEELT 205
+L+ + + ++LED I + Q N L K +L+E ++
Sbjct: 970 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERIS 1009
Score = 45.4 bits (106), Expect = 3e-05
Identities = 54/225 (24%), Positives = 108/225 (48%), Gaps = 27/225 (12%)
Query: 5 LSLDHPSAKENQALRLIEMREEN---GNVPKTEQAGSLKPLRDTGKSNL--------KEK 53
L +D + K ++ +L+E R + + E+A +L L++ +S + KE+
Sbjct: 988 LVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEE 1047
Query: 54 KANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLK----EENSQQQLAAERRLQDVRQKF 109
K+ +L++++++ + + IA+LQ I+ LK ++ + Q A R ++ QK
Sbjct: 1048 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1107
Query: 110 EDEKKQLIRDNDQAIKVLQDELENRSNQVRCAEKKLQ---------HKELESQEQITYIR 160
KK IR+ + I LQ++L++ AEK+ + ELE T +
Sbjct: 1108 NALKK--IRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQ 1165
Query: 161 QEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASILQEELT 205
QE K + + L++ L++ S ++QV ++++ + EELT
Sbjct: 1166 QELRAKREQEVTV-LKKALDEETRSHEAQVQEMRQKHAQAVEELT 1209
Score = 40.8 bits (94), Expect = 8e-04
Identities = 50/192 (26%), Positives = 91/192 (47%), Gaps = 26/192 (13%)
Query: 22 EMREENGNVPK--TEQAGSLKPLRDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAE 79
EMR+++ + TEQ K K+NL + K + +EKE ++ + E
Sbjct: 1196 EMRQKHAQAVEELTEQLEQFK----RAKANLDKNK-----QTLEKE-------NADLAGE 1239
Query: 80 LQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQVR 139
L+ + K+E ++ E ++Q+++ K D ++ ND+ K LQ+E+E+ + +
Sbjct: 1240 LRV-LGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHK-LQNEVESVTGMLN 1297
Query: 140 CAEKKL-----QHKELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQ 194
AE K L SQ Q T + ET+ K + LRQ LE+ +SL+ Q++
Sbjct: 1298 EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQ-LEEERNSLQDQLDEEM 1356
Query: 195 KRASILQEELTT 206
+ L+ ++T
Sbjct: 1357 EAKQNLERHIST 1368
Score = 39.3 bits (90), Expect = 0.002
Identities = 45/196 (22%), Positives = 89/196 (45%), Gaps = 29/196 (14%)
Query: 7 LDHPSAKENQALRLIEMREENGNVPKT-EQAGSLKPLRDTGKSNLKEKKANSKLKQIEKE 65
LD A++N AL+ I RE G++ E S + R+ K+ +++ +L+ ++ E
Sbjct: 1099 LDDEIAQKNNALKKI--RELEGHISDLQEDLDSERAARN--KAEKQKRDLGEELEALKTE 1154
Query: 66 YTQKL---AKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQ 122
L A ++ A+ + ++ LK+ ++ + E ++Q++RQK + Q
Sbjct: 1155 LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQK-----------HAQ 1203
Query: 123 AIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDT 182
A++ L ++LE +K Q E E+ + +R + +QE+E
Sbjct: 1204 AVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELR----------VLGQAKQEVEHK 1253
Query: 183 ISSLKSQVNFLQKRAS 198
L++QV LQ + S
Sbjct: 1254 KKKLEAQVQELQSKCS 1269
Score = 38.5 bits (88), Expect = 0.004
Identities = 37/181 (20%), Positives = 89/181 (49%), Gaps = 8/181 (4%)
Query: 12 AKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQIEKEYTQKLA 71
A ++ + + E+ N TE++ + K + + K+ SKL ++E K
Sbjct: 1754 AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFK 1813
Query: 72 KSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQL--IRDNDQAIKVLQD 129
+ IA L+ I+ L+E+ Q+ + + ++QK + K+ L + D + + ++
Sbjct: 1814 ST---IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE 1870
Query: 130 ELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQ 189
+ E + +V+ +++L+ E ESQ +I R++ + +L ++ + + +++LKS+
Sbjct: 1871 QAEKGNARVKQLKRQLEEAEEESQ-RINANRRKLQRELDEATESN--EAMGREVNALKSK 1927
Query: 190 V 190
+
Sbjct: 1928 L 1928
Score = 37.7 bits (86), Expect = 0.007
Identities = 58/227 (25%), Positives = 99/227 (43%), Gaps = 45/227 (19%)
Query: 16 QALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLK-QIEKEYTQ------ 68
+AL E E + K E + D GK+ + +K+ L+ Q+E+ TQ
Sbjct: 1494 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 1553
Query: 69 KLAKSSQIIAELQTTISSLK-----------EENSQQQLAAERRLQDVRQKFEDEKKQLI 117
+L + L+ + +LK E+N +++ +R+L + + EDE+KQ
Sbjct: 1554 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRA 1613
Query: 118 RDNDQAIKVLQDELENRSNQVRCAEK----------KLQ------HKELE----SQEQIT 157
A K L+ +L++ Q A K KLQ +ELE S+++I
Sbjct: 1614 L-AAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIF 1672
Query: 158 YIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASILQEEL 204
+E E K K L A L Q ED ++ ++ +K+A + +EEL
Sbjct: 1673 ATAKENEKKAKSL-EADLMQLQEDLAAAERA-----RKQADLEKEEL 1713
Score = 31.6 bits (70), Expect = 0.51
Identities = 41/194 (21%), Positives = 77/194 (39%), Gaps = 38/194 (19%)
Query: 32 KTEQAGSLKPLRDTGKSNLKEK--------KANSKLKQIEKEYTQKLAKSSQIIA---EL 80
K + G LK L S +K + K +++K ++E A +I A E
Sbjct: 1619 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1678
Query: 81 QTTISSLKEE--NSQQQLAAERRLQ------------------DVRQKFEDEKKQLIRDN 120
+ SL+ + Q+ LAA R + R +DEK++L
Sbjct: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRL---- 1734
Query: 121 DQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELE 180
+ I L++ELE + +++ ++++ + E T K S RQ+LE
Sbjct: 1735 EARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKN---ESARQQLE 1791
Query: 181 DTISSLKSQVNFLQ 194
L+S+++ ++
Sbjct: 1792 RQNKELRSKLHEME 1805
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 47.0 bits (110), Expect = 1e-05
Identities = 37/160 (23%), Positives = 81/160 (50%), Gaps = 14/160 (8%)
Query: 47 KSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVR 106
K+ +++KA ++LK++E++++Q + + + +LQ ++ +L AE VR
Sbjct: 870 KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQ----------AETELYAEAEEMRVR 919
Query: 107 QKFEDEKKQLIRDNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIR-QEYET 165
KKQ + + ++ +E E+R Q++ KK+ + L+ +EQ+ +
Sbjct: 920 LA---AKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 976
Query: 166 KLKGLMPASLRQELEDTISSLKSQVNFLQKRASILQEELT 205
+L+ + + ++LED I + Q N L K +L+E ++
Sbjct: 977 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERIS 1016
Score = 45.4 bits (106), Expect = 3e-05
Identities = 54/225 (24%), Positives = 108/225 (48%), Gaps = 27/225 (12%)
Query: 5 LSLDHPSAKENQALRLIEMREEN---GNVPKTEQAGSLKPLRDTGKSNL--------KEK 53
L +D + K ++ +L+E R + + E+A +L L++ +S + KE+
Sbjct: 995 LVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEE 1054
Query: 54 KANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLK----EENSQQQLAAERRLQDVRQKF 109
K+ +L++++++ + + IA+LQ I+ LK ++ + Q A R ++ QK
Sbjct: 1055 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1114
Query: 110 EDEKKQLIRDNDQAIKVLQDELENRSNQVRCAEKKLQ---------HKELESQEQITYIR 160
KK IR+ + I LQ++L++ AEK+ + ELE T +
Sbjct: 1115 NALKK--IRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQ 1172
Query: 161 QEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASILQEELT 205
QE K + + L++ L++ S ++QV ++++ + EELT
Sbjct: 1173 QELRAKREQEVTV-LKKALDEETRSHEAQVQEMRQKHAQAVEELT 1216
Score = 40.8 bits (94), Expect = 8e-04
Identities = 50/192 (26%), Positives = 91/192 (47%), Gaps = 26/192 (13%)
Query: 22 EMREENGNVPK--TEQAGSLKPLRDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAE 79
EMR+++ + TEQ K K+NL + K + +EKE ++ + E
Sbjct: 1203 EMRQKHAQAVEELTEQLEQFK----RAKANLDKNK-----QTLEKE-------NADLAGE 1246
Query: 80 LQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQVR 139
L+ + K+E ++ E ++Q+++ K D ++ ND+ K LQ+E+E+ + +
Sbjct: 1247 LRV-LGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHK-LQNEVESVTGMLN 1304
Query: 140 CAEKKL-----QHKELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQ 194
AE K L SQ Q T + ET+ K + LRQ LE+ +SL+ Q++
Sbjct: 1305 EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQ-LEEERNSLQDQLDEEM 1363
Query: 195 KRASILQEELTT 206
+ L+ ++T
Sbjct: 1364 EAKQNLERHIST 1375
Score = 39.3 bits (90), Expect = 0.002
Identities = 45/196 (22%), Positives = 89/196 (45%), Gaps = 29/196 (14%)
Query: 7 LDHPSAKENQALRLIEMREENGNVPKT-EQAGSLKPLRDTGKSNLKEKKANSKLKQIEKE 65
LD A++N AL+ I RE G++ E S + R+ K+ +++ +L+ ++ E
Sbjct: 1106 LDDEIAQKNNALKKI--RELEGHISDLQEDLDSERAARN--KAEKQKRDLGEELEALKTE 1161
Query: 66 YTQKL---AKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQ 122
L A ++ A+ + ++ LK+ ++ + E ++Q++RQK + Q
Sbjct: 1162 LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQK-----------HAQ 1210
Query: 123 AIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDT 182
A++ L ++LE +K Q E E+ + +R + +QE+E
Sbjct: 1211 AVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELR----------VLGQAKQEVEHK 1260
Query: 183 ISSLKSQVNFLQKRAS 198
L++QV LQ + S
Sbjct: 1261 KKKLEAQVQELQSKCS 1276
Score = 38.5 bits (88), Expect = 0.004
Identities = 37/181 (20%), Positives = 89/181 (49%), Gaps = 8/181 (4%)
Query: 12 AKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQIEKEYTQKLA 71
A ++ + + E+ N TE++ + K + + K+ SKL ++E K
Sbjct: 1761 AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFK 1820
Query: 72 KSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQL--IRDNDQAIKVLQD 129
+ IA L+ I+ L+E+ Q+ + + ++QK + K+ L + D + + ++
Sbjct: 1821 ST---IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE 1877
Query: 130 ELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQ 189
+ E + +V+ +++L+ E ESQ +I R++ + +L ++ + + +++LKS+
Sbjct: 1878 QAEKGNARVKQLKRQLEEAEEESQ-RINANRRKLQRELDEATESN--EAMGREVNALKSK 1934
Query: 190 V 190
+
Sbjct: 1935 L 1935
Score = 37.7 bits (86), Expect = 0.007
Identities = 58/227 (25%), Positives = 99/227 (43%), Gaps = 45/227 (19%)
Query: 16 QALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLK-QIEKEYTQ------ 68
+AL E E + K E + D GK+ + +K+ L+ Q+E+ TQ
Sbjct: 1501 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 1560
Query: 69 KLAKSSQIIAELQTTISSLK-----------EENSQQQLAAERRLQDVRQKFEDEKKQLI 117
+L + L+ + +LK E+N +++ +R+L + + EDE+KQ
Sbjct: 1561 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRA 1620
Query: 118 RDNDQAIKVLQDELENRSNQVRCAEK----------KLQ------HKELE----SQEQIT 157
A K L+ +L++ Q A K KLQ +ELE S+++I
Sbjct: 1621 L-AAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIF 1679
Query: 158 YIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASILQEEL 204
+E E K K L A L Q ED ++ ++ +K+A + +EEL
Sbjct: 1680 ATAKENEKKAKSL-EADLMQLQEDLAAAERA-----RKQADLEKEEL 1720
Score = 31.6 bits (70), Expect = 0.51
Identities = 41/194 (21%), Positives = 77/194 (39%), Gaps = 38/194 (19%)
Query: 32 KTEQAGSLKPLRDTGKSNLKEK--------KANSKLKQIEKEYTQKLAKSSQIIA---EL 80
K + G LK L S +K + K +++K ++E A +I A E
Sbjct: 1626 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1685
Query: 81 QTTISSLKEE--NSQQQLAAERRLQ------------------DVRQKFEDEKKQLIRDN 120
+ SL+ + Q+ LAA R + R +DEK++L
Sbjct: 1686 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRL---- 1741
Query: 121 DQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELE 180
+ I L++ELE + +++ ++++ + E T K S RQ+LE
Sbjct: 1742 EARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKN---ESARQQLE 1798
Query: 181 DTISSLKSQVNFLQ 194
L+S+++ ++
Sbjct: 1799 RQNKELRSKLHEME 1812
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 47.0 bits (110), Expect = 1e-05
Identities = 37/160 (23%), Positives = 81/160 (50%), Gaps = 14/160 (8%)
Query: 47 KSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVR 106
K+ +++KA ++LK++E++++Q + + + +LQ ++ +L AE VR
Sbjct: 870 KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQ----------AETELYAEAEEMRVR 919
Query: 107 QKFEDEKKQLIRDNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIR-QEYET 165
KKQ + + ++ +E E+R Q++ KK+ + L+ +EQ+ +
Sbjct: 920 LA---AKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 976
Query: 166 KLKGLMPASLRQELEDTISSLKSQVNFLQKRASILQEELT 205
+L+ + + ++LED I + Q N L K +L+E ++
Sbjct: 977 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERIS 1016
Score = 45.4 bits (106), Expect = 3e-05
Identities = 54/225 (24%), Positives = 108/225 (48%), Gaps = 27/225 (12%)
Query: 5 LSLDHPSAKENQALRLIEMREEN---GNVPKTEQAGSLKPLRDTGKSNL--------KEK 53
L +D + K ++ +L+E R + + E+A +L L++ +S + KE+
Sbjct: 995 LVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEE 1054
Query: 54 KANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLK----EENSQQQLAAERRLQDVRQKF 109
K+ +L++++++ + + IA+LQ I+ LK ++ + Q A R ++ QK
Sbjct: 1055 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1114
Query: 110 EDEKKQLIRDNDQAIKVLQDELENRSNQVRCAEKKLQ---------HKELESQEQITYIR 160
KK IR+ + I LQ++L++ AEK+ + ELE T +
Sbjct: 1115 NALKK--IRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQ 1172
Query: 161 QEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASILQEELT 205
QE K + + L++ L++ S ++QV ++++ + EELT
Sbjct: 1173 QELRAKREQEVTV-LKKALDEETRSHEAQVQEMRQKHAQAVEELT 1216
Score = 40.8 bits (94), Expect = 8e-04
Identities = 50/192 (26%), Positives = 91/192 (47%), Gaps = 26/192 (13%)
Query: 22 EMREENGNVPK--TEQAGSLKPLRDTGKSNLKEKKANSKLKQIEKEYTQKLAKSSQIIAE 79
EMR+++ + TEQ K K+NL + K + +EKE ++ + E
Sbjct: 1203 EMRQKHAQAVEELTEQLEQFK----RAKANLDKNK-----QTLEKE-------NADLAGE 1246
Query: 80 LQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQVR 139
L+ + K+E ++ E ++Q+++ K D ++ ND+ K LQ+E+E+ + +
Sbjct: 1247 LRV-LGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHK-LQNEVESVTGMLN 1304
Query: 140 CAEKKL-----QHKELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQ 194
AE K L SQ Q T + ET+ K + LRQ LE+ +SL+ Q++
Sbjct: 1305 EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQ-LEEERNSLQDQLDEEM 1363
Query: 195 KRASILQEELTT 206
+ L+ ++T
Sbjct: 1364 EAKQNLERHIST 1375
Score = 40.4 bits (93), Expect = 0.001
Identities = 43/188 (22%), Positives = 84/188 (44%), Gaps = 25/188 (13%)
Query: 12 AKENQALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLKQIEKEYTQKLA 71
A ++ + + E+ N TE++ + K + + K+ SKL ++E K
Sbjct: 1761 AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFK 1820
Query: 72 KSSQIIAELQTTISSLKEENSQQ----QLAA------ERRLQDVRQKFEDEKKQLIRDND 121
+ IA L+ I+ L+E+ Q+ Q A +++L+++ + EDE+K + +
Sbjct: 1821 ST---IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE 1877
Query: 122 QA---------IKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQE---YETKLKG 169
QA +K +E E S ++ +KLQ + E+ E + +E ++KL+G
Sbjct: 1878 QAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRG 1937
Query: 170 LMPASLRQ 177
P Q
Sbjct: 1938 PPPQETSQ 1945
Score = 39.3 bits (90), Expect = 0.002
Identities = 45/196 (22%), Positives = 89/196 (45%), Gaps = 29/196 (14%)
Query: 7 LDHPSAKENQALRLIEMREENGNVPKT-EQAGSLKPLRDTGKSNLKEKKANSKLKQIEKE 65
LD A++N AL+ I RE G++ E S + R+ K+ +++ +L+ ++ E
Sbjct: 1106 LDDEIAQKNNALKKI--RELEGHISDLQEDLDSERAARN--KAEKQKRDLGEELEALKTE 1161
Query: 66 YTQKL---AKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQ 122
L A ++ A+ + ++ LK+ ++ + E ++Q++RQK + Q
Sbjct: 1162 LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQK-----------HAQ 1210
Query: 123 AIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDT 182
A++ L ++LE +K Q E E+ + +R + +QE+E
Sbjct: 1211 AVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELR----------VLGQAKQEVEHK 1260
Query: 183 ISSLKSQVNFLQKRAS 198
L++QV LQ + S
Sbjct: 1261 KKKLEAQVQELQSKCS 1276
Score = 37.7 bits (86), Expect = 0.007
Identities = 58/227 (25%), Positives = 99/227 (43%), Gaps = 45/227 (19%)
Query: 16 QALRLIEMREENGNVPKTEQAGSLKPLRDTGKSNLKEKKANSKLK-QIEKEYTQ------ 68
+AL E E + K E + D GK+ + +K+ L+ Q+E+ TQ
Sbjct: 1501 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 1560
Query: 69 KLAKSSQIIAELQTTISSLK-----------EENSQQQLAAERRLQDVRQKFEDEKKQLI 117
+L + L+ + +LK E+N +++ +R+L + + EDE+KQ
Sbjct: 1561 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRA 1620
Query: 118 RDNDQAIKVLQDELENRSNQVRCAEK----------KLQ------HKELE----SQEQIT 157
A K L+ +L++ Q A K KLQ +ELE S+++I
Sbjct: 1621 L-AAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIF 1679
Query: 158 YIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASILQEEL 204
+E E K K L A L Q ED ++ ++ +K+A + +EEL
Sbjct: 1680 ATAKENEKKAKSL-EADLMQLQEDLAAAERA-----RKQADLEKEEL 1720
Score = 31.6 bits (70), Expect = 0.51
Identities = 41/194 (21%), Positives = 77/194 (39%), Gaps = 38/194 (19%)
Query: 32 KTEQAGSLKPLRDTGKSNLKEK--------KANSKLKQIEKEYTQKLAKSSQIIA---EL 80
K + G LK L S +K + K +++K ++E A +I A E
Sbjct: 1626 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1685
Query: 81 QTTISSLKEE--NSQQQLAAERRLQ------------------DVRQKFEDEKKQLIRDN 120
+ SL+ + Q+ LAA R + R +DEK++L
Sbjct: 1686 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRL---- 1741
Query: 121 DQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELE 180
+ I L++ELE + +++ ++++ + E T K S RQ+LE
Sbjct: 1742 EARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKN---ESARQQLE 1798
Query: 181 DTISSLKSQVNFLQ 194
L+S+++ ++
Sbjct: 1799 RQNKELRSKLHEME 1812
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.123 0.311
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,801,538
Number of Sequences: 37866
Number of extensions: 293640
Number of successful extensions: 4757
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 237
Number of HSP's successfully gapped in prelim test: 814
Number of HSP's that attempted gapping in prelim test: 2393
Number of HSP's gapped (non-prelim): 2454
length of query: 211
length of database: 18,247,518
effective HSP length: 98
effective length of query: 113
effective length of database: 14,536,650
effective search space: 1642641450
effective search space used: 1642641450
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.