Guide to the Human Genome
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Search of human proteins with 82830440

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|82830440 Fanconi anemia, complementation group I isoform 2
[Homo sapiens]
         (1268 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|82830440 Fanconi anemia, complementation group I isoform 2 [H...  2453   0.0  
gi|164607124 Fanconi anemia, complementation group I isoform 1 [...  2262   0.0  
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]         39   0.024
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]         39   0.024
gi|217272804 hyaluronan-mediated motility receptor isoform d [Ho...    39   0.024
gi|217272802 hyaluronan-mediated motility receptor isoform a [Ho...    39   0.024
gi|217416398 hyaluronan-mediated motility receptor isoform c [Ho...    39   0.024
gi|217416394 hyaluronan-mediated motility receptor isoform b [Ho...    39   0.024
gi|66528888 Fanconi anemia complementation group D2 isoform b [H...    39   0.032
gi|21361861 Fanconi anemia complementation group D2 isoform a [H...    39   0.032
gi|55770834 centromere protein F [Homo sapiens]                        34   0.78 
gi|4508005 tripartite motif-containing 26 [Homo sapiens]               33   1.3  
gi|7662316 HIV-1 Vpr binding protein [Homo sapiens]                    33   1.7  
gi|39995064 pannexin 1 [Homo sapiens]                                  33   1.7  
gi|156104869 chloride channel 2 [Homo sapiens]                         33   2.3  
gi|226246630 tryptophan rich basic protein isoform 2 [Homo sapiens]    33   2.3  
gi|21536428 tryptophan rich basic protein isoform 1 [Homo sapiens]     33   2.3  
gi|65287717 eukaryotic translation initiation factor 2 alpha kin...    33   2.3  
gi|189217904 RPGRIP1-like isoform b [Homo sapiens]                     32   3.0  
gi|118442834 RPGRIP1-like isoform a [Homo sapiens]                     32   3.0  
gi|58219006 radial spoke head 4 homolog A isoform 1 [Homo sapiens]     32   3.9  
gi|27597090 suppressor of Ty 6 homolog [Homo sapiens]                  32   3.9  
gi|153070822 methylmalonic aciduria (cobalamin deficiency) cblC ...    31   6.6  
gi|117414135 apoptosis inhibitor [Homo sapiens]                        31   6.6  
gi|4503257 death-domain associated protein isoform a [Homo sapiens]    31   8.6  
gi|215422388 death-domain associated protein isoform a [Homo sap...    31   8.6  
gi|215422366 death-domain associated protein isoform b [Homo sap...    31   8.6  
gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo ...    31   8.6  
gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo ...    31   8.6  
gi|23957698 luman-recruiting factor [Homo sapiens]                     31   8.6  

>gi|82830440 Fanconi anemia, complementation group I isoform 2 [Homo
            sapiens]
          Length = 1268

 Score = 2453 bits (6357), Expect = 0.0
 Identities = 1268/1268 (100%), Positives = 1268/1268 (100%)

Query: 1    MDQKILSLAAEKTADKLQEFLQTLREGDLTNLLQNQAVKGKVAGALLRAIFKGSPCSEEA 60
            MDQKILSLAAEKTADKLQEFLQTLREGDLTNLLQNQAVKGKVAGALLRAIFKGSPCSEEA
Sbjct: 1    MDQKILSLAAEKTADKLQEFLQTLREGDLTNLLQNQAVKGKVAGALLRAIFKGSPCSEEA 60

Query: 61   GTLRRRKIYTCCIQLVESGDLQKEIASEIIGLLMLEAHHFPGPLLVELANEFISAVREGS 120
            GTLRRRKIYTCCIQLVESGDLQKEIASEIIGLLMLEAHHFPGPLLVELANEFISAVREGS
Sbjct: 61   GTLRRRKIYTCCIQLVESGDLQKEIASEIIGLLMLEAHHFPGPLLVELANEFISAVREGS 120

Query: 121  LVNGKSLELLPIILTALATKKENLAYGKGVLSGEECKKQLINTLCSGRWDQQYVIQLTSM 180
            LVNGKSLELLPIILTALATKKENLAYGKGVLSGEECKKQLINTLCSGRWDQQYVIQLTSM
Sbjct: 121  LVNGKSLELLPIILTALATKKENLAYGKGVLSGEECKKQLINTLCSGRWDQQYVIQLTSM 180

Query: 181  FKDVPLTAEEVEFVVEKALSMFSKMNLQEIPPLVYQLLVLSSKGSRKSVLEGIIAFFSAL 240
            FKDVPLTAEEVEFVVEKALSMFSKMNLQEIPPLVYQLLVLSSKGSRKSVLEGIIAFFSAL
Sbjct: 181  FKDVPLTAEEVEFVVEKALSMFSKMNLQEIPPLVYQLLVLSSKGSRKSVLEGIIAFFSAL 240

Query: 241  DKQHNEEQSGDELLDVVTVPSGELRHVEGTIILHIVFAIKLDYELGRELVKHLKVGQQGD 300
            DKQHNEEQSGDELLDVVTVPSGELRHVEGTIILHIVFAIKLDYELGRELVKHLKVGQQGD
Sbjct: 241  DKQHNEEQSGDELLDVVTVPSGELRHVEGTIILHIVFAIKLDYELGRELVKHLKVGQQGD 300

Query: 301  SNNNLSPFSIALLLSVTRIQRFQDQVLDLLKTSVVKSFKDLQLLQGSKFLQNLVPHRSYV 360
            SNNNLSPFSIALLLSVTRIQRFQDQVLDLLKTSVVKSFKDLQLLQGSKFLQNLVPHRSYV
Sbjct: 301  SNNNLSPFSIALLLSVTRIQRFQDQVLDLLKTSVVKSFKDLQLLQGSKFLQNLVPHRSYV 360

Query: 361  STMILEVVKNSVHSWDHVTQGLVELGFILMDSYGPKKVLDGKTIETSPSLSRMPNQHACK 420
            STMILEVVKNSVHSWDHVTQGLVELGFILMDSYGPKKVLDGKTIETSPSLSRMPNQHACK
Sbjct: 361  STMILEVVKNSVHSWDHVTQGLVELGFILMDSYGPKKVLDGKTIETSPSLSRMPNQHACK 420

Query: 421  LGANILLETFKIHEMIRQEILEQVLNRVVTRASSPISHFLDLLSNIVMYAPLVLQSCSSK 480
            LGANILLETFKIHEMIRQEILEQVLNRVVTRASSPISHFLDLLSNIVMYAPLVLQSCSSK
Sbjct: 421  LGANILLETFKIHEMIRQEILEQVLNRVVTRASSPISHFLDLLSNIVMYAPLVLQSCSSK 480

Query: 481  VTEAFDYLSFLPLQTVQRLLKAVQPLLKVSMSMRDCLILVLRKAMFANQLDARKSAVAGF 540
            VTEAFDYLSFLPLQTVQRLLKAVQPLLKVSMSMRDCLILVLRKAMFANQLDARKSAVAGF
Sbjct: 481  VTEAFDYLSFLPLQTVQRLLKAVQPLLKVSMSMRDCLILVLRKAMFANQLDARKSAVAGF 540

Query: 541  LLLLKNFKVLGSLSSSQCSQSLSVSQVHVDVHSHYNSVANETFCLEIMDSLRRCLSQQAD 600
            LLLLKNFKVLGSLSSSQCSQSLSVSQVHVDVHSHYNSVANETFCLEIMDSLRRCLSQQAD
Sbjct: 541  LLLLKNFKVLGSLSSSQCSQSLSVSQVHVDVHSHYNSVANETFCLEIMDSLRRCLSQQAD 600

Query: 601  VRLMLYEGFYDVLRRNSQLANSVMQTLLSQLKQFYEPKPDLLPPLKLEACILTQGDKISL 660
            VRLMLYEGFYDVLRRNSQLANSVMQTLLSQLKQFYEPKPDLLPPLKLEACILTQGDKISL
Sbjct: 601  VRLMLYEGFYDVLRRNSQLANSVMQTLLSQLKQFYEPKPDLLPPLKLEACILTQGDKISL 660

Query: 661  QEPLDYLLCCIQHCLAWYKNTVIPLQQGEEEEEEEEAFYEDLDDILESITNRMIKSELED 720
            QEPLDYLLCCIQHCLAWYKNTVIPLQQGEEEEEEEEAFYEDLDDILESITNRMIKSELED
Sbjct: 661  QEPLDYLLCCIQHCLAWYKNTVIPLQQGEEEEEEEEAFYEDLDDILESITNRMIKSELED 720

Query: 721  FELDKSADFSQSTSIGIKNNICAFLVMGVCEVLIEYNFSISSFSKNRFEDILSLFMCYKK 780
            FELDKSADFSQSTSIGIKNNICAFLVMGVCEVLIEYNFSISSFSKNRFEDILSLFMCYKK
Sbjct: 721  FELDKSADFSQSTSIGIKNNICAFLVMGVCEVLIEYNFSISSFSKNRFEDILSLFMCYKK 780

Query: 781  LSDILNEKAGKAKTKMANKTSDSLLSMKFVSSLLTALFRVLLWRYTSIPTSVEESGKKEK 840
            LSDILNEKAGKAKTKMANKTSDSLLSMKFVSSLLTALFRVLLWRYTSIPTSVEESGKKEK
Sbjct: 781  LSDILNEKAGKAKTKMANKTSDSLLSMKFVSSLLTALFRVLLWRYTSIPTSVEESGKKEK 840

Query: 841  GKSISLLCLEGLQKIFSAVQQFYQPKIQQFLRALDVTDKEGEEREDADVSVTQRTAFQIR 900
            GKSISLLCLEGLQKIFSAVQQFYQPKIQQFLRALDVTDKEGEEREDADVSVTQRTAFQIR
Sbjct: 841  GKSISLLCLEGLQKIFSAVQQFYQPKIQQFLRALDVTDKEGEEREDADVSVTQRTAFQIR 900

Query: 901  QFQRSLLNLLSSQEEDFNSKEALLLVTVLTSLSKLLEPSSPQFVQMLSWTSKICKENSRE 960
            QFQRSLLNLLSSQEEDFNSKEALLLVTVLTSLSKLLEPSSPQFVQMLSWTSKICKENSRE
Sbjct: 901  QFQRSLLNLLSSQEEDFNSKEALLLVTVLTSLSKLLEPSSPQFVQMLSWTSKICKENSRE 960

Query: 961  DALFCKSLMNLLFSLHVSYKSPVILLRDLSQDIHGHLGDIDQDVEVEKTNHFAIVNLRTA 1020
            DALFCKSLMNLLFSLHVSYKSPVILLRDLSQDIHGHLGDIDQDVEVEKTNHFAIVNLRTA
Sbjct: 961  DALFCKSLMNLLFSLHVSYKSPVILLRDLSQDIHGHLGDIDQDVEVEKTNHFAIVNLRTA 1020

Query: 1021 APTVCLLVLSQAEKVLEEVDWLITKLKGQVSQETLSEEASSQATLPNQPVEKAIIMQLGT 1080
            APTVCLLVLSQAEKVLEEVDWLITKLKGQVSQETLSEEASSQATLPNQPVEKAIIMQLGT
Sbjct: 1021 APTVCLLVLSQAEKVLEEVDWLITKLKGQVSQETLSEEASSQATLPNQPVEKAIIMQLGT 1080

Query: 1081 LLTFFHELVQTALPSGSCVDTLLKDLCKMYTTLTALVRYYLQVCQSSGGIPKNMEKLVKL 1140
            LLTFFHELVQTALPSGSCVDTLLKDLCKMYTTLTALVRYYLQVCQSSGGIPKNMEKLVKL
Sbjct: 1081 LLTFFHELVQTALPSGSCVDTLLKDLCKMYTTLTALVRYYLQVCQSSGGIPKNMEKLVKL 1140

Query: 1141 SGSHLTPLCYSFISYVQNKSKSLNYTGEKKEKPAAVATAMARVLRETKPIPNLIFAIEQY 1200
            SGSHLTPLCYSFISYVQNKSKSLNYTGEKKEKPAAVATAMARVLRETKPIPNLIFAIEQY
Sbjct: 1141 SGSHLTPLCYSFISYVQNKSKSLNYTGEKKEKPAAVATAMARVLRETKPIPNLIFAIEQY 1200

Query: 1201 EKFLIHLSKKSKVNLMQHMKLSTSRDFKIKGNILDMVLREDGEDENEEGTASEHGGQNKE 1260
            EKFLIHLSKKSKVNLMQHMKLSTSRDFKIKGNILDMVLREDGEDENEEGTASEHGGQNKE
Sbjct: 1201 EKFLIHLSKKSKVNLMQHMKLSTSRDFKIKGNILDMVLREDGEDENEEGTASEHGGQNKE 1260

Query: 1261 PAKKKRKK 1268
            PAKKKRKK
Sbjct: 1261 PAKKKRKK 1268


>gi|164607124 Fanconi anemia, complementation group I isoform 1 [Homo
            sapiens]
          Length = 1328

 Score = 2262 bits (5861), Expect = 0.0
 Identities = 1198/1329 (90%), Positives = 1220/1329 (91%), Gaps = 62/1329 (4%)

Query: 1    MDQKILSLAAEKTADKLQEFLQTLREGDLTNLLQNQAVKGKVAGALLRAIFKGSPCSEEA 60
            MDQKILSLAAEKTADKLQEFLQTLREGDLTNLLQNQAVKGKVAGALLRAIFKGSPCSEEA
Sbjct: 1    MDQKILSLAAEKTADKLQEFLQTLREGDLTNLLQNQAVKGKVAGALLRAIFKGSPCSEEA 60

Query: 61   GTLRRRKIYTCCIQLVESGDLQKEIASEIIGLLMLEAHHFPGPLLVELANEFISAVREGS 120
            GTLRRRKIYTCCIQLVESGDLQKEIASEIIGLLMLEAHHFPGPLLVELANEFISAVREGS
Sbjct: 61   GTLRRRKIYTCCIQLVESGDLQKEIASEIIGLLMLEAHHFPGPLLVELANEFISAVREGS 120

Query: 121  LVNGKSLELLPIILTALATKKENLAYGKGVLSGEECKKQLINTLCSGRWDQQYVIQLTSM 180
            LVNGKSLELLPIILTALATKKENLAYGKGVLSGEECKKQLINTLCSGRWDQQYVIQLTSM
Sbjct: 121  LVNGKSLELLPIILTALATKKENLAYGKGVLSGEECKKQLINTLCSGRWDQQYVIQLTSM 180

Query: 181  FKDVPLTAEEVEFVVEKALSMFSKMNLQEIPPLVYQLLVLSSKGSRKSVLEGIIAFFSAL 240
            FKDVPLTAEEVEFVVEKALSMFSKMNLQEIPPLVYQLLVLSSKGSRKSVLEGIIAFFSAL
Sbjct: 181  FKDVPLTAEEVEFVVEKALSMFSKMNLQEIPPLVYQLLVLSSKGSRKSVLEGIIAFFSAL 240

Query: 241  DKQHNEEQSGDELLDVVTVPSGELRHVEGTIILHIVFAIKLDYELGRELVKHLKVGQQGD 300
            DKQHNEEQSGDELLDVVTVPSGELRHVEGTIILHIVFAIKLDYELGRELVKHLKVGQQGD
Sbjct: 241  DKQHNEEQSGDELLDVVTVPSGELRHVEGTIILHIVFAIKLDYELGRELVKHLKVGQQGD 300

Query: 301  SNNNLSPFSIALLLSVTRIQRFQDQVLDLLKTSVVKSFKDLQLLQGSKFLQNLVPHRSYV 360
            SNNNLSPFSIALLLSVTRIQRFQDQVLDLLKTSVVKSFKDLQLLQGSKFLQNLVPHRSYV
Sbjct: 301  SNNNLSPFSIALLLSVTRIQRFQDQVLDLLKTSVVKSFKDLQLLQGSKFLQNLVPHRSYV 360

Query: 361  STMILEVVKNSVHSWDHVTQGLVELGFILMDSYGPKKVLDGKTIETSPSLSRMPNQHACK 420
            STMILEVVKNSVHSWDHVTQGLVELGFILMDSYGPKKVLDGKTIETSPSLSRMPNQHACK
Sbjct: 361  STMILEVVKNSVHSWDHVTQGLVELGFILMDSYGPKKVLDGKTIETSPSLSRMPNQHACK 420

Query: 421  LGANILLETFKIHEMIRQEILEQVLNRVVTRASSPISHFLDLLSNIVMYAPLVLQSCSSK 480
            LGANILLETFKIHEMIRQEILEQVLNRVVTRASSPISHFLDLLSNIVMYAPLVLQSCSSK
Sbjct: 421  LGANILLETFKIHEMIRQEILEQVLNRVVTRASSPISHFLDLLSNIVMYAPLVLQSCSSK 480

Query: 481  VTEAFDYLSFLPLQTVQRLLKAVQPLLKVSMSMRDCLILVLRKAMFANQLDARKSAVAGF 540
            VTEAFDYLSFLPLQTVQRLLKAVQPLLKVSMSMRDCLILVLRKAMFANQLDARKSAVAGF
Sbjct: 481  VTEAFDYLSFLPLQTVQRLLKAVQPLLKVSMSMRDCLILVLRKAMFANQLDARKSAVAGF 540

Query: 541  LLLLKNFKVLGSLSSSQCSQSLSVSQVHVDVHSHYNSVANETFCLEIMDSLRRCLSQQAD 600
            LLLLKNFKVLGSLSSSQCSQSLSVSQVHVDVHSHYNSVANETFCLEIMDSLRRCLSQQAD
Sbjct: 541  LLLLKNFKVLGSLSSSQCSQSLSVSQVHVDVHSHYNSVANETFCLEIMDSLRRCLSQQAD 600

Query: 601  VRLMLYEGFYDVLRRNSQLANSVMQTLLSQLKQFYEPKPDLLPPLKLEACILTQGDKISL 660
            VRLMLYEGFYDVLRRNSQLANSVMQTLLSQLKQFYEPKPDLLPPLKLEACILTQGDKISL
Sbjct: 601  VRLMLYEGFYDVLRRNSQLANSVMQTLLSQLKQFYEPKPDLLPPLKLEACILTQGDKISL 660

Query: 661  QEPLDYLLCCIQHCLAWYKNTVIPLQQGEEEEEEEEAFYEDLDDILESITNRMIKSELED 720
            QEPLDYLLCCIQHCLAWYKNTVIPLQQGEEEEEEEEAFYEDLDDILESITNRMIKSELED
Sbjct: 661  QEPLDYLLCCIQHCLAWYKNTVIPLQQGEEEEEEEEAFYEDLDDILESITNRMIKSELED 720

Query: 721  FELDKSADFSQSTSIGIKNNICAFLVMGVCEVLIEYNFSISSFSKNRFEDILSLFMCYKK 780
            FELDKSADFSQSTSIGIKNNICAFLVMGVCEVLIEYNFSISSFSKNRFEDILSLFMCYKK
Sbjct: 721  FELDKSADFSQSTSIGIKNNICAFLVMGVCEVLIEYNFSISSFSKNRFEDILSLFMCYKK 780

Query: 781  LSDILNEKAGKAKTKMANKTSDSLLSMKFVSSLLTALFRVLLWRYTSIPTSVEESGK--- 837
            LSDILNEKAGKAKTKMANKTSDSLLSMKFVSSLLTALFR  +  +    + +  S +   
Sbjct: 781  LSDILNEKAGKAKTKMANKTSDSLLSMKFVSSLLTALFRDSIQSHQESLSVLRSSNEFMR 840

Query: 838  -------------KEKGKSISLLCLEGLQKIFSAVQQFYQPKIQQFLRALDVTDKEGEER 884
                         KE G  +S    +  +KIF  +    +  + ++       ++ G++ 
Sbjct: 841  YAVNVALQKVQQLKETG-HVSGPDGQNPEKIFQNLCDITRVLLWRYTSIPTSVEESGKKE 899

Query: 885  EDADVS-------------VTQRTAFQIRQFQRSL------------------------- 906
            +   +S             V Q    +I+QF R+L                         
Sbjct: 900  KGKSISLLCLEGLQKIFSAVQQFYQPKIQQFLRALDVTDKEGEEREDADVSVTQRTAFQI 959

Query: 907  -------LNLLSSQEEDFNSKEALLLVTVLTSLSKLLEPSSPQFVQMLSWTSKICKENSR 959
                   LNLLSSQEEDFNSKEALLLVTVLTSLSKLLEPSSPQFVQMLSWTSKICKENSR
Sbjct: 960  RQFQRSLLNLLSSQEEDFNSKEALLLVTVLTSLSKLLEPSSPQFVQMLSWTSKICKENSR 1019

Query: 960  EDALFCKSLMNLLFSLHVSYKSPVILLRDLSQDIHGHLGDIDQDVEVEKTNHFAIVNLRT 1019
            EDALFCKSLMNLLFSLHVSYKSPVILLRDLSQDIHGHLGDIDQDVEVEKTNHFAIVNLRT
Sbjct: 1020 EDALFCKSLMNLLFSLHVSYKSPVILLRDLSQDIHGHLGDIDQDVEVEKTNHFAIVNLRT 1079

Query: 1020 AAPTVCLLVLSQAEKVLEEVDWLITKLKGQVSQETLSEEASSQATLPNQPVEKAIIMQLG 1079
            AAPTVCLLVLSQAEKVLEEVDWLITKLKGQVSQETLSEEASSQATLPNQPVEKAIIMQLG
Sbjct: 1080 AAPTVCLLVLSQAEKVLEEVDWLITKLKGQVSQETLSEEASSQATLPNQPVEKAIIMQLG 1139

Query: 1080 TLLTFFHELVQTALPSGSCVDTLLKDLCKMYTTLTALVRYYLQVCQSSGGIPKNMEKLVK 1139
            TLLTFFHELVQTALPSGSCVDTLLKDLCKMYTTLTALVRYYLQVCQSSGGIPKNMEKLVK
Sbjct: 1140 TLLTFFHELVQTALPSGSCVDTLLKDLCKMYTTLTALVRYYLQVCQSSGGIPKNMEKLVK 1199

Query: 1140 LSGSHLTPLCYSFISYVQNKSKSLNYTGEKKEKPAAVATAMARVLRETKPIPNLIFAIEQ 1199
            LSGSHLTPLCYSFISYVQNKSKSLNYTGEKKEKPAAVATAMARVLRETKPIPNLIFAIEQ
Sbjct: 1200 LSGSHLTPLCYSFISYVQNKSKSLNYTGEKKEKPAAVATAMARVLRETKPIPNLIFAIEQ 1259

Query: 1200 YEKFLIHLSKKSKVNLMQHMKLSTSRDFKIKGNILDMVLREDGEDENEEGTASEHGGQNK 1259
            YEKFLIHLSKKSKVNLMQHMKLSTSRDFKIKGNILDMVLREDGEDENEEGTASEHGGQNK
Sbjct: 1260 YEKFLIHLSKKSKVNLMQHMKLSTSRDFKIKGNILDMVLREDGEDENEEGTASEHGGQNK 1319

Query: 1260 EPAKKKRKK 1268
            EPAKKKRKK
Sbjct: 1320 EPAKKKRKK 1328


>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
          Length = 3907

 Score = 39.3 bits (90), Expect = 0.024
 Identities = 40/183 (21%), Positives = 86/183 (46%), Gaps = 17/183 (9%)

Query: 842  KSISLLCLEGLQKIFSAVQQFYQPKIQQFLRALDVTDKEGEEREDADVSVTQRTAFQIRQ 901
            K++S  C   LQ + S + ++Y P ++  + A D  +      E+ D  + Q   ++++ 
Sbjct: 1193 KAVSEECSYFLQTLCSVLGEYYTPALKCEVNAEDKENSGDYISENEDPEL-QDYRYEVQD 1251

Query: 902  FQRSLLNLLSSQEEDFNSKEALLLVTVLTSLSKLLEPSSPQFVQMLSWTSKICKENSRED 961
            FQ ++  LL+   E++N      L+ + T LSK+    +   +++      + KE +  +
Sbjct: 1252 FQENMHTLLNKVTEEYNK-----LLVLQTRLSKIWGQQT-DGMKLEFGEENLPKEET--E 1303

Query: 962  ALFCKSLMNLLFSLHVSYKSPVILLRDLS--------QDIHGHLGDIDQDVEVEKTNHFA 1013
             L   S M  L  + V++KS +  L+DL         Q++   +  + Q ++  + N+ A
Sbjct: 1304 FLSIHSQMTNLEDIDVNHKSKLSSLQDLEKTKLEEQVQELESLISSLQQQLKETEQNYEA 1363

Query: 1014 IVN 1016
             ++
Sbjct: 1364 EIH 1366


>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
          Length = 3899

 Score = 39.3 bits (90), Expect = 0.024
 Identities = 40/183 (21%), Positives = 86/183 (46%), Gaps = 17/183 (9%)

Query: 842  KSISLLCLEGLQKIFSAVQQFYQPKIQQFLRALDVTDKEGEEREDADVSVTQRTAFQIRQ 901
            K++S  C   LQ + S + ++Y P ++  + A D  +      E+ D  + Q   ++++ 
Sbjct: 1193 KAVSEECSYFLQTLCSVLGEYYTPALKCEVNAEDKENSGDYISENEDPEL-QDYRYEVQD 1251

Query: 902  FQRSLLNLLSSQEEDFNSKEALLLVTVLTSLSKLLEPSSPQFVQMLSWTSKICKENSRED 961
            FQ ++  LL+   E++N      L+ + T LSK+    +   +++      + KE +  +
Sbjct: 1252 FQENMHTLLNKVTEEYNK-----LLVLQTRLSKIWGQQT-DGMKLEFGEENLPKEET--E 1303

Query: 962  ALFCKSLMNLLFSLHVSYKSPVILLRDLS--------QDIHGHLGDIDQDVEVEKTNHFA 1013
             L   S M  L  + V++KS +  L+DL         Q++   +  + Q ++  + N+ A
Sbjct: 1304 FLSIHSQMTNLEDIDVNHKSKLSSLQDLEKTKLEEQVQELESLISSLQQQLKETEQNYEA 1363

Query: 1014 IVN 1016
             ++
Sbjct: 1364 EIH 1366


>gi|217272804 hyaluronan-mediated motility receptor isoform d [Homo
            sapiens]
          Length = 638

 Score = 39.3 bits (90), Expect = 0.024
 Identities = 82/378 (21%), Positives = 152/378 (40%), Gaps = 46/378 (12%)

Query: 714  IKSELEDFELDKSADFSQSTSIGIKNNICAFLVMGVCEVLIEYNFSISSFSKNRFEDILS 773
            +++ELE  E   +A   + TS+   N   A L   + E+        S FS+N  +  L 
Sbjct: 22   LETELEKMEARLNAALREKTSLSANN---ATLEKQLIELTRTNELLKSKFSENGNQKNLR 78

Query: 774  LFMCYKKLSDILNEKAGKAKTKMANKTSDSLLSMKFVSSLLTALFRVLLWRYTSIPTSVE 833
            +     +L  + N++  K +  MA +    +       SL  +  ++       +  S+E
Sbjct: 79   ILSL--ELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLV--SIE 134

Query: 834  ESGKKEKGKSISLLCLEGLQKIFSAVQQFYQPKIQQFLRALDVTDKEGEEREDADVSVTQ 893
            +    EK ++  LL  E +++I  A  Q  + K       LD+   E   +E  D  ++ 
Sbjct: 135  KEKIDEKSETEKLL--EYIEEISCASDQVEKYK-------LDIAQLEENLKEKNDEILS- 184

Query: 894  RTAFQIRQFQRSLLNLLSSQEEDFNSKEALLLVTVLTSLSKLLEPSSPQFVQMLSWTSKI 953
                 ++Q     + +LS Q ED N K  LL       +++  E +     +M +   K 
Sbjct: 185  -----LKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKF 239

Query: 954  CKENSREDALFCKSLM---------NLLFSLH---VSYKSPVILLRDL-SQDIHGHLGDI 1000
              E    + L  K L           L  SLH    S++  ++  ++L  +++   L ++
Sbjct: 240  ILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDEL 299

Query: 1001 DQDVEVEKTNHFAIVNLRTAAPTVCLLVLSQAEKVLEEVDWLITKLKGQVSQETLSEEAS 1060
            D+  + E+     +  L             +A+   EE+  L  KLKG+ ++   S  A 
Sbjct: 300  DKLQQKEEQAERLVKQLE-----------EEAKSRAEELKLLEEKLKGKEAELEKSSAAH 348

Query: 1061 SQATLPNQPVEKAIIMQL 1078
            +QATL  Q    +++  L
Sbjct: 349  TQATLLLQEKYDSMVQSL 366


>gi|217272802 hyaluronan-mediated motility receptor isoform a [Homo
            sapiens]
          Length = 725

 Score = 39.3 bits (90), Expect = 0.024
 Identities = 82/378 (21%), Positives = 152/378 (40%), Gaps = 46/378 (12%)

Query: 714  IKSELEDFELDKSADFSQSTSIGIKNNICAFLVMGVCEVLIEYNFSISSFSKNRFEDILS 773
            +++ELE  E   +A   + TS+   N   A L   + E+        S FS+N  +  L 
Sbjct: 109  LETELEKMEARLNAALREKTSLSANN---ATLEKQLIELTRTNELLKSKFSENGNQKNLR 165

Query: 774  LFMCYKKLSDILNEKAGKAKTKMANKTSDSLLSMKFVSSLLTALFRVLLWRYTSIPTSVE 833
            +     +L  + N++  K +  MA +    +       SL  +  ++       +  S+E
Sbjct: 166  ILSL--ELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLV--SIE 221

Query: 834  ESGKKEKGKSISLLCLEGLQKIFSAVQQFYQPKIQQFLRALDVTDKEGEEREDADVSVTQ 893
            +    EK ++  LL  E +++I  A  Q  + K       LD+   E   +E  D  ++ 
Sbjct: 222  KEKIDEKSETEKLL--EYIEEISCASDQVEKYK-------LDIAQLEENLKEKNDEILS- 271

Query: 894  RTAFQIRQFQRSLLNLLSSQEEDFNSKEALLLVTVLTSLSKLLEPSSPQFVQMLSWTSKI 953
                 ++Q     + +LS Q ED N K  LL       +++  E +     +M +   K 
Sbjct: 272  -----LKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKF 326

Query: 954  CKENSREDALFCKSLM---------NLLFSLH---VSYKSPVILLRDL-SQDIHGHLGDI 1000
              E    + L  K L           L  SLH    S++  ++  ++L  +++   L ++
Sbjct: 327  ILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDEL 386

Query: 1001 DQDVEVEKTNHFAIVNLRTAAPTVCLLVLSQAEKVLEEVDWLITKLKGQVSQETLSEEAS 1060
            D+  + E+     +  L             +A+   EE+  L  KLKG+ ++   S  A 
Sbjct: 387  DKLQQKEEQAERLVKQLE-----------EEAKSRAEELKLLEEKLKGKEAELEKSSAAH 435

Query: 1061 SQATLPNQPVEKAIIMQL 1078
            +QATL  Q    +++  L
Sbjct: 436  TQATLLLQEKYDSMVQSL 453


>gi|217416398 hyaluronan-mediated motility receptor isoform c [Homo
            sapiens]
          Length = 709

 Score = 39.3 bits (90), Expect = 0.024
 Identities = 82/378 (21%), Positives = 152/378 (40%), Gaps = 46/378 (12%)

Query: 714  IKSELEDFELDKSADFSQSTSIGIKNNICAFLVMGVCEVLIEYNFSISSFSKNRFEDILS 773
            +++ELE  E   +A   + TS+   N   A L   + E+        S FS+N  +  L 
Sbjct: 93   LETELEKMEARLNAALREKTSLSANN---ATLEKQLIELTRTNELLKSKFSENGNQKNLR 149

Query: 774  LFMCYKKLSDILNEKAGKAKTKMANKTSDSLLSMKFVSSLLTALFRVLLWRYTSIPTSVE 833
            +     +L  + N++  K +  MA +    +       SL  +  ++       +  S+E
Sbjct: 150  ILSL--ELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLV--SIE 205

Query: 834  ESGKKEKGKSISLLCLEGLQKIFSAVQQFYQPKIQQFLRALDVTDKEGEEREDADVSVTQ 893
            +    EK ++  LL  E +++I  A  Q  + K       LD+   E   +E  D  ++ 
Sbjct: 206  KEKIDEKSETEKLL--EYIEEISCASDQVEKYK-------LDIAQLEENLKEKNDEILS- 255

Query: 894  RTAFQIRQFQRSLLNLLSSQEEDFNSKEALLLVTVLTSLSKLLEPSSPQFVQMLSWTSKI 953
                 ++Q     + +LS Q ED N K  LL       +++  E +     +M +   K 
Sbjct: 256  -----LKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKF 310

Query: 954  CKENSREDALFCKSLM---------NLLFSLH---VSYKSPVILLRDL-SQDIHGHLGDI 1000
              E    + L  K L           L  SLH    S++  ++  ++L  +++   L ++
Sbjct: 311  ILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDEL 370

Query: 1001 DQDVEVEKTNHFAIVNLRTAAPTVCLLVLSQAEKVLEEVDWLITKLKGQVSQETLSEEAS 1060
            D+  + E+     +  L             +A+   EE+  L  KLKG+ ++   S  A 
Sbjct: 371  DKLQQKEEQAERLVKQLE-----------EEAKSRAEELKLLEEKLKGKEAELEKSSAAH 419

Query: 1061 SQATLPNQPVEKAIIMQL 1078
            +QATL  Q    +++  L
Sbjct: 420  TQATLLLQEKYDSMVQSL 437


>gi|217416394 hyaluronan-mediated motility receptor isoform b [Homo
            sapiens]
          Length = 724

 Score = 39.3 bits (90), Expect = 0.024
 Identities = 82/378 (21%), Positives = 152/378 (40%), Gaps = 46/378 (12%)

Query: 714  IKSELEDFELDKSADFSQSTSIGIKNNICAFLVMGVCEVLIEYNFSISSFSKNRFEDILS 773
            +++ELE  E   +A   + TS+   N   A L   + E+        S FS+N  +  L 
Sbjct: 108  LETELEKMEARLNAALREKTSLSANN---ATLEKQLIELTRTNELLKSKFSENGNQKNLR 164

Query: 774  LFMCYKKLSDILNEKAGKAKTKMANKTSDSLLSMKFVSSLLTALFRVLLWRYTSIPTSVE 833
            +     +L  + N++  K +  MA +    +       SL  +  ++       +  S+E
Sbjct: 165  ILSL--ELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLV--SIE 220

Query: 834  ESGKKEKGKSISLLCLEGLQKIFSAVQQFYQPKIQQFLRALDVTDKEGEEREDADVSVTQ 893
            +    EK ++  LL  E +++I  A  Q  + K       LD+   E   +E  D  ++ 
Sbjct: 221  KEKIDEKSETEKLL--EYIEEISCASDQVEKYK-------LDIAQLEENLKEKNDEILS- 270

Query: 894  RTAFQIRQFQRSLLNLLSSQEEDFNSKEALLLVTVLTSLSKLLEPSSPQFVQMLSWTSKI 953
                 ++Q     + +LS Q ED N K  LL       +++  E +     +M +   K 
Sbjct: 271  -----LKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKF 325

Query: 954  CKENSREDALFCKSLM---------NLLFSLH---VSYKSPVILLRDL-SQDIHGHLGDI 1000
              E    + L  K L           L  SLH    S++  ++  ++L  +++   L ++
Sbjct: 326  ILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDEL 385

Query: 1001 DQDVEVEKTNHFAIVNLRTAAPTVCLLVLSQAEKVLEEVDWLITKLKGQVSQETLSEEAS 1060
            D+  + E+     +  L             +A+   EE+  L  KLKG+ ++   S  A 
Sbjct: 386  DKLQQKEEQAERLVKQLE-----------EEAKSRAEELKLLEEKLKGKEAELEKSSAAH 434

Query: 1061 SQATLPNQPVEKAIIMQL 1078
            +QATL  Q    +++  L
Sbjct: 435  TQATLLLQEKYDSMVQSL 452


>gi|66528888 Fanconi anemia complementation group D2 isoform b [Homo
           sapiens]
          Length = 1451

 Score = 38.9 bits (89), Expect = 0.032
 Identities = 88/488 (18%), Positives = 189/488 (38%), Gaps = 86/488 (17%)

Query: 404 IETSPSLSRMPNQHACKLGANILLETFKIHEMI-RQEILEQVLNRVVTRASSPISHFLDL 462
           +  + SL    +Q     G+ +    FK  +   +QE++  ++  + +   + +   LD+
Sbjct: 436 LSLAQSLLHSLDQSIISFGSLLYKYAFKFFDTYCQQEVVGALVTHICSGNEAEVDTALDV 495

Query: 463 LSNIVMYAPLVLQSCSSKVTEAFDYLSFLPLQTVQRLLKAVQPLL-----KVSMSMRDCL 517
           L  +V+  P  +   +  V    DYL  +  Q +++L   +  L      + S  ++D +
Sbjct: 496 LLELVVLNPSAMMMNAVFVKGILDYLDNISPQQIRKLFYVLSTLAFSKQNEASSHIQDDM 555

Query: 518 ILVLRKAMFANQLDARKSAVAGFLLLLKNFKVLGSLSSSQCSQSLSVSQVHVDVHSHYNS 577
            LV+RK + +     +   + G +        +  + ++  S+S S++Q   ++      
Sbjct: 556 HLVIRKQLSSTVFKYKLIGIIGAV-------TMAGIMAADRSESPSLTQERANLSD--EQ 606

Query: 578 VANETFCLEIMDSLRRCLSQQADVRLMLYEGFYDVLRR---NSQLANSVMQTLLSQLKQF 634
               T  L+++ S   C  Q      + Y+ F ++++    + +    V  T+ +     
Sbjct: 607 CTQVTSLLQLVHS---CSEQSPQASALYYDEFANLIQHEKLDPKALEWVGHTICN----- 658

Query: 635 YEPKPDLLPPLKLEACILTQGDKISLQEPLDYLLCCIQHCLAWYKNTVIPLQQGEEEEEE 694
                D      +++C++ +GD      P+  L                    G EE + 
Sbjct: 659 -----DFQDAFVVDSCVVPEGD---FPFPVKAL-------------------YGLEEYDT 691

Query: 695 EEAFYEDLDDILESITNRMIKSELEDFELDKSADFSQSTSIGIKNNICAFLVMGVCEVLI 754
           ++    +L  +L S          +DF  D     SQ +   + + +C      +  + +
Sbjct: 692 QDGIAINLLPLLFS----------QDFAKDGGPVTSQESGQKLVSPLCLAPYFRLLRLCV 741

Query: 755 EYNFSISSFSKNRFEDILSLFMCYKKLSDILNEKAGKAKTKMANKTSDSLLSMKFVSSLL 814
           E   +         E+I  L  C   L+D+  E   K ++  A + S       F+ SL 
Sbjct: 742 ERQHN------GNLEEIDGLLDCPIFLTDL--EPGEKLESMSAKERS-------FMCSL- 785

Query: 815 TALFRVLLWRYTSIPTSVEESGKKEKGKSIS----LLCLEGLQKIFSAVQQFYQPKIQQF 870
             +F  L W    +    +E+  + KGK ++    ++ L+ + + + AV   Y P +  F
Sbjct: 786 --IFLTLNWFREIVNAFCQETSPEMKGKVLTRLKHIVELQIILEKYLAVTPDYVPPLGNF 843

Query: 871 -LRALDVT 877
            +  LD+T
Sbjct: 844 DVETLDIT 851


>gi|21361861 Fanconi anemia complementation group D2 isoform a [Homo
           sapiens]
          Length = 1471

 Score = 38.9 bits (89), Expect = 0.032
 Identities = 88/488 (18%), Positives = 189/488 (38%), Gaps = 86/488 (17%)

Query: 404 IETSPSLSRMPNQHACKLGANILLETFKIHEMI-RQEILEQVLNRVVTRASSPISHFLDL 462
           +  + SL    +Q     G+ +    FK  +   +QE++  ++  + +   + +   LD+
Sbjct: 436 LSLAQSLLHSLDQSIISFGSLLYKYAFKFFDTYCQQEVVGALVTHICSGNEAEVDTALDV 495

Query: 463 LSNIVMYAPLVLQSCSSKVTEAFDYLSFLPLQTVQRLLKAVQPLL-----KVSMSMRDCL 517
           L  +V+  P  +   +  V    DYL  +  Q +++L   +  L      + S  ++D +
Sbjct: 496 LLELVVLNPSAMMMNAVFVKGILDYLDNISPQQIRKLFYVLSTLAFSKQNEASSHIQDDM 555

Query: 518 ILVLRKAMFANQLDARKSAVAGFLLLLKNFKVLGSLSSSQCSQSLSVSQVHVDVHSHYNS 577
            LV+RK + +     +   + G +        +  + ++  S+S S++Q   ++      
Sbjct: 556 HLVIRKQLSSTVFKYKLIGIIGAV-------TMAGIMAADRSESPSLTQERANLSD--EQ 606

Query: 578 VANETFCLEIMDSLRRCLSQQADVRLMLYEGFYDVLRR---NSQLANSVMQTLLSQLKQF 634
               T  L+++ S   C  Q      + Y+ F ++++    + +    V  T+ +     
Sbjct: 607 CTQVTSLLQLVHS---CSEQSPQASALYYDEFANLIQHEKLDPKALEWVGHTICN----- 658

Query: 635 YEPKPDLLPPLKLEACILTQGDKISLQEPLDYLLCCIQHCLAWYKNTVIPLQQGEEEEEE 694
                D      +++C++ +GD      P+  L                    G EE + 
Sbjct: 659 -----DFQDAFVVDSCVVPEGD---FPFPVKAL-------------------YGLEEYDT 691

Query: 695 EEAFYEDLDDILESITNRMIKSELEDFELDKSADFSQSTSIGIKNNICAFLVMGVCEVLI 754
           ++    +L  +L S          +DF  D     SQ +   + + +C      +  + +
Sbjct: 692 QDGIAINLLPLLFS----------QDFAKDGGPVTSQESGQKLVSPLCLAPYFRLLRLCV 741

Query: 755 EYNFSISSFSKNRFEDILSLFMCYKKLSDILNEKAGKAKTKMANKTSDSLLSMKFVSSLL 814
           E   +         E+I  L  C   L+D+  E   K ++  A + S       F+ SL 
Sbjct: 742 ERQHN------GNLEEIDGLLDCPIFLTDL--EPGEKLESMSAKERS-------FMCSL- 785

Query: 815 TALFRVLLWRYTSIPTSVEESGKKEKGKSIS----LLCLEGLQKIFSAVQQFYQPKIQQF 870
             +F  L W    +    +E+  + KGK ++    ++ L+ + + + AV   Y P +  F
Sbjct: 786 --IFLTLNWFREIVNAFCQETSPEMKGKVLTRLKHIVELQIILEKYLAVTPDYVPPLGNF 843

Query: 871 -LRALDVT 877
            +  LD+T
Sbjct: 844 DVETLDIT 851


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 34.3 bits (77), Expect = 0.78
 Identities = 107/513 (20%), Positives = 205/513 (39%), Gaps = 41/513 (7%)

Query: 522  RKAMFANQLDARKSAVAGFLLLLKNFKVLGSLSSSQCSQSLSVSQVHVDVHSHYNSVANE 581
            +KA     L+A    +   L   +NF     + +   SQ   +  +   ++   NS+  E
Sbjct: 497  QKAREVCHLEAELKNIKQCLNQSQNFAE--EMKAKNTSQETMLRDLQEKINQQENSLTLE 554

Query: 582  TFCLEIMD--SLRRCLSQQADVRLMLYEGFYDVLRRNSQLANSVMQTLLSQLKQFYEPKP 639
               L + D    R C       R    E   D L +  + + +++  L  + K++ E K 
Sbjct: 555  KLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKE 614

Query: 640  D--LLPPLKLE-ACILTQ--GDKISLQEPLDYLLCCI---QHCLAWYKNTVIPLQQGEEE 691
            +  L    K E   +LTQ   +K +LQ  +++L  C+   Q     Y   V  L+   E 
Sbjct: 615  EKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDREN 674

Query: 692  EEEEEAFYEDLDDILESITNRMIKSELEDFELDKSADFSQSTSIGIKNNIC--AFLVMGV 749
               E     +L ++L+S +  +   +L   EL + A+FS         N+C     + G 
Sbjct: 675  LSVE---IRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQ 731

Query: 750  CEVLIEYNFSISSFSKNRFEDILSLFMCYKKLSDILNEKAGKAKTKMANKTSDSLLSMKF 809
             E L      +S+   ++      L   Y+ L D+L  K     T   ++   SLL+   
Sbjct: 732  VEDLEHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASLVTNEDHQR--SLLAFDQ 789

Query: 810  VSSLLTALFRVLLWRYTSIPTSVE----ESGKKEKGKSISLLCLEGLQKIFSAVQQFYQP 865
              ++  + F  ++    S+P+       E+ +  K  +I    ++ L+    + +Q    
Sbjct: 790  QPAMHHS-FANIIGEQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSD 848

Query: 866  KIQQFLRALDVTDKEGEEREDADVSVTQRTAFQIRQFQRSLLNLLSSQEEDFNSKEALLL 925
              +Q    + +   +GE  E+   +     +F     QR     +S  +ED ++ + ++ 
Sbjct: 849  LQKQCEELVQI---KGEIEENLMKAEQMHQSFVAETSQR-----ISKLQEDTSAHQNVVA 900

Query: 926  VTV--LTSLSKLLEPSSPQFVQMLSWTSKICKENS-REDALFCKSLMNLLFSLHVSYKSP 982
             T+  L +  K L+  + +     +   ++ K N   ED+L    L++   SL     S 
Sbjct: 901  ETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSS 960

Query: 983  VILL-----RDLSQDIHGHLGDIDQDVEVEKTN 1010
            +I L      +L+Q+ +G L +I+  +  EK N
Sbjct: 961  IISLNKREIEELTQE-NGTLKEINASLNQEKMN 992


>gi|4508005 tripartite motif-containing 26 [Homo sapiens]
          Length = 539

 Score = 33.5 bits (75), Expect = 1.3
 Identities = 18/52 (34%), Positives = 30/52 (57%)

Query: 686 QQGEEEEEEEEAFYEDLDDILESITNRMIKSELEDFELDKSADFSQSTSIGI 737
           ++GEEEEEEEEA Y D  D  E+  +     + E+ E ++  +  +S  +G+
Sbjct: 390 EEGEEEEEEEEAGYGDGYDDWETDEDEESLGDEEEEEEEEEEEVLESCMVGV 441


>gi|7662316 HIV-1 Vpr binding protein [Homo sapiens]
          Length = 1507

 Score = 33.1 bits (74), Expect = 1.7
 Identities = 17/53 (32%), Positives = 36/53 (67%), Gaps = 6/53 (11%)

Query: 686  QQGEEEEEEEEAFYEDLDDILESITNRMIKSELEDFELDKSA------DFSQS 732
            ++ E+EEE+++   +D DD+ E  T++++++ELE+ + +++A      DFS S
Sbjct: 1405 EEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPS 1457


>gi|39995064 pannexin 1 [Homo sapiens]
          Length = 426

 Score = 33.1 bits (74), Expect = 1.7
 Identities = 38/111 (34%), Positives = 52/111 (46%), Gaps = 15/111 (13%)

Query: 325 QVLDLLKTSVVKSFK-----DLQLLQGSKFLQ-NLVPHRSYVSTMILEVVKNSVHSWDHV 378
           +V ++L T  V  FK     DL L   + FL+ N+   +SY    +LE +K+S    D +
Sbjct: 307 KVYEILPTFDVLHFKSEGYNDLSLY--NLFLEENISEVKSYKCLKVLENIKSSGQGIDPM 364

Query: 379 TQGLVELGFILMDSYGPKKVLDGKTIETSPSLSRMPNQHACKLGANILLET 429
              L  LG I MD      V+DGKT  ++       NQ A   G NI  ET
Sbjct: 365 LL-LTNLGMIKMD------VVDGKTPMSAEMREEQGNQTAELQGMNIDSET 408


>gi|156104869 chloride channel 2 [Homo sapiens]
          Length = 898

 Score = 32.7 bits (73), Expect = 2.3
 Identities = 21/64 (32%), Positives = 33/64 (51%), Gaps = 4/64 (6%)

Query: 31  NLLQNQAVKGKVAGALLRAIFKGSP----CSEEAGTLRRRKIYTCCIQLVESGDLQKEIA 86
           NL ++     + AG  LR++F GSP     SE+  +  +RK+    I L    DL+ E++
Sbjct: 708 NLGESPTGSAESAGIALRSLFCGSPPPEAASEKLESCEKRKLKRVRISLASDADLEGEMS 767

Query: 87  SEII 90
            E I
Sbjct: 768 PEEI 771


>gi|226246630 tryptophan rich basic protein isoform 2 [Homo sapiens]
          Length = 140

 Score = 32.7 bits (73), Expect = 2.3
 Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 6/71 (8%)

Query: 770 DILSLFMCYKKLSDILNEKAGKAKTKMANKTSDSLLSMKFVSS-----LLTALFRVLLWR 824
           +++  F  Y +L   +N+   K KT +  +T+  L  +K+V S     L  AL   L+W+
Sbjct: 30  NMMDEFARYARLERKINKMTDKLKTHVKARTAQ-LAKIKWVISVAFYVLQAALMISLIWK 88

Query: 825 YTSIPTSVEES 835
           Y S+P +V  S
Sbjct: 89  YYSVPVAVVPS 99


>gi|21536428 tryptophan rich basic protein isoform 1 [Homo sapiens]
          Length = 174

 Score = 32.7 bits (73), Expect = 2.3
 Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 6/71 (8%)

Query: 770 DILSLFMCYKKLSDILNEKAGKAKTKMANKTSDSLLSMKFVSS-----LLTALFRVLLWR 824
           +++  F  Y +L   +N+   K KT +  +T+  L  +K+V S     L  AL   L+W+
Sbjct: 64  NMMDEFARYARLERKINKMTDKLKTHVKARTAQ-LAKIKWVISVAFYVLQAALMISLIWK 122

Query: 825 YTSIPTSVEES 835
           Y S+P +V  S
Sbjct: 123 YYSVPVAVVPS 133


>gi|65287717 eukaryotic translation initiation factor 2 alpha kinase 4
            [Homo sapiens]
          Length = 1649

 Score = 32.7 bits (73), Expect = 2.3
 Identities = 42/189 (22%), Positives = 82/189 (43%), Gaps = 19/189 (10%)

Query: 899  IRQFQRSLLNLLSSQEEDFNSKEALLLVTVLTSLSKLLEPSSPQFVQMLSWTSKICKENS 958
            + Q+Q+ +   L+SQE++   K    +    T  + L++ S P  V+ L+   K   ++ 
Sbjct: 314  VLQWQKKMGPFLTSQEKEKIDKCKKQIQGTETEFNSLVKLSHPNVVRYLAMNLKEQDDSI 373

Query: 959  REDALFCKSLMNLLFSLHVSYKSPVIL--LRDLSQDIHGHLGDIDQDVEVEKTNHFAIVN 1016
              D L  + +  +  + H+S+  P+ +  LR  +  +   L  +  +  V K    +  N
Sbjct: 374  VVDIL-VEHISGVSLAAHLSHSGPIPVHQLRRYTAQLLSGLDYLHSNSVVHKV--LSASN 430

Query: 1017 LRTAAPTVCLLVLSQAEKVLEEVDWLITKLKGQVSQETLSEEAS---SQATLPNQPVEKA 1073
                       VL  AE  ++  D+ I+K    + +E + E+     S   LP +  +K 
Sbjct: 431  -----------VLVDAEGTVKITDYSISKRLADICKEDVFEQTRVRFSDNALPYKTGKKG 479

Query: 1074 IIMQLGTLL 1082
             + +LG LL
Sbjct: 480  DVWRLGLLL 488


>gi|189217904 RPGRIP1-like isoform b [Homo sapiens]
          Length = 1235

 Score = 32.3 bits (72), Expect = 3.0
 Identities = 48/257 (18%), Positives = 103/257 (40%), Gaps = 36/257 (14%)

Query: 651 ILTQGDKISLQEPLDYLLCCIQ----HCLAWYKNTVIPLQQGEEE-EEEEEAFYEDLDDI 705
           ++  GD++++Q     L CC      H + + +  +  LQ    + E+E E   E+ D +
Sbjct: 306 LMANGDELNMQLKEQRLKCCSLEKQLHSMKFSERRIEELQDRINDLEKERELLKENYDKL 365

Query: 706 LES-----------ITNRMIKSELEDFELDKSADFSQSTSI----GIKNNICAFLVMGVC 750
            +S           +  + +K ++   E    +D +  T I      + +    LV    
Sbjct: 366 YDSAFSAAHEEQWKLKEQQLKVQIAQLETALKSDLTDKTEILDRLKTERDQNEKLVQENR 425

Query: 751 EVLIEYNFSISSFSKNRFEDILSLFMCYKKLSDILNEKAGKA----KTKMANKTSDSLLS 806
           E+ ++Y        K + +++      Y + +DI  ++  +A    K +   K  D    
Sbjct: 426 ELQLQY-----LEQKQQLDELKKRIKLYNQENDINADELSEALLLIKAQKEQKNGDLSFL 480

Query: 807 MKFVSSLLTALFRVLLWRYTSIPTSVEESGK-------KEKGKSISLLCLEGLQKIFSAV 859
           +K  S +   L R +     +   +V+E  K       + K      + +E + +    +
Sbjct: 481 VKVDSEINKDLERSMRELQATHAETVQELEKTRNMLIMQHKINKDYQMEVEAVTRKMENL 540

Query: 860 QQFYQPKIQQFLRALDV 876
           QQ Y+ K++Q++  LD+
Sbjct: 541 QQDYELKVEQYVHLLDI 557


>gi|118442834 RPGRIP1-like isoform a [Homo sapiens]
          Length = 1315

 Score = 32.3 bits (72), Expect = 3.0
 Identities = 48/257 (18%), Positives = 103/257 (40%), Gaps = 36/257 (14%)

Query: 651 ILTQGDKISLQEPLDYLLCCIQ----HCLAWYKNTVIPLQQGEEE-EEEEEAFYEDLDDI 705
           ++  GD++++Q     L CC      H + + +  +  LQ    + E+E E   E+ D +
Sbjct: 306 LMANGDELNMQLKEQRLKCCSLEKQLHSMKFSERRIEELQDRINDLEKERELLKENYDKL 365

Query: 706 LES-----------ITNRMIKSELEDFELDKSADFSQSTSI----GIKNNICAFLVMGVC 750
            +S           +  + +K ++   E    +D +  T I      + +    LV    
Sbjct: 366 YDSAFSAAHEEQWKLKEQQLKVQIAQLETALKSDLTDKTEILDRLKTERDQNEKLVQENR 425

Query: 751 EVLIEYNFSISSFSKNRFEDILSLFMCYKKLSDILNEKAGKA----KTKMANKTSDSLLS 806
           E+ ++Y        K + +++      Y + +DI  ++  +A    K +   K  D    
Sbjct: 426 ELQLQY-----LEQKQQLDELKKRIKLYNQENDINADELSEALLLIKAQKEQKNGDLSFL 480

Query: 807 MKFVSSLLTALFRVLLWRYTSIPTSVEESGK-------KEKGKSISLLCLEGLQKIFSAV 859
           +K  S +   L R +     +   +V+E  K       + K      + +E + +    +
Sbjct: 481 VKVDSEINKDLERSMRELQATHAETVQELEKTRNMLIMQHKINKDYQMEVEAVTRKMENL 540

Query: 860 QQFYQPKIQQFLRALDV 876
           QQ Y+ K++Q++  LD+
Sbjct: 541 QQDYELKVEQYVHLLDI 557


>gi|58219006 radial spoke head 4 homolog A isoform 1 [Homo sapiens]
          Length = 716

 Score = 32.0 bits (71), Expect = 3.9
 Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 1/67 (1%)

Query: 658 ISLQEPLDYLLCCIQHCLAWYK-NTVIPLQQGEEEEEEEEAFYEDLDDILESITNRMIKS 716
           I L E L   +  +QH L+  + N    +Q+ EEEEEEE+   +D D I + +   ++  
Sbjct: 535 IDLVESLSNWVHHVQHILSQGRCNWFNSIQKNEEEEEEEDEEKDDSDYIEQEVGLPLLTP 594

Query: 717 ELEDFEL 723
             ED E+
Sbjct: 595 ISEDLEI 601


>gi|27597090 suppressor of Ty 6 homolog [Homo sapiens]
          Length = 1726

 Score = 32.0 bits (71), Expect = 3.9
 Identities = 14/39 (35%), Positives = 21/39 (53%)

Query: 1230 KGNILDMVLREDGEDENEEGTASEHGGQNKEPAKKKRKK 1268
            +GN+   +  +D EDE EE   S+ G    +   KKRK+
Sbjct: 51   QGNLKGFINDDDDEDEGEEDEGSDSGDSEDDVGHKKRKR 89


>gi|153070822 methylmalonic aciduria (cobalamin deficiency) cblC
           type, with homocystinuria [Homo sapiens]
          Length = 282

 Score = 31.2 bits (69), Expect = 6.6
 Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 8/56 (14%)

Query: 639 PDLLPPLKLEACILTQGDKISLQEPLDYLLCCIQHCLAW-YKNTVIPLQQGEEEEE 693
           PDL PP K   C+ T+ D+I+L E  ++      H   W Y++ V P ++  EE++
Sbjct: 172 PDL-PPRKPHDCVPTRADRIALLEGFNF------HWRDWTYRDAVTPQERYSEEQK 220


>gi|117414135 apoptosis inhibitor [Homo sapiens]
          Length = 127

 Score = 31.2 bits (69), Expect = 6.6
 Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 2/93 (2%)

Query: 724 DKSADFSQSTSIGIKNNICAFLVMGVCEVLIEYNFSISSFSKNRFEDILSLFM--CYKKL 781
           D S     S+S   ++ +    ++   +++  ++   S F+K  ++  +  +M    +KL
Sbjct: 32  DDSLIGRNSSSESTEDEVTESTIITSVDIVTNHHLQESIFTKEAYKKYIKDYMKSINEKL 91

Query: 782 SDILNEKAGKAKTKMANKTSDSLLSMKFVSSLL 814
            +   E+     T M NK+S SLL  K  SSLL
Sbjct: 92  EEQRPERVKLFITGMKNKSSTSLLIFKTTSSLL 124


>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
          Length = 740

 Score = 30.8 bits (68), Expect = 8.6
 Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 4/58 (6%)

Query: 686 QQGEEEEEEEEAF----YEDLDDILESITNRMIKSELEDFELDKSADFSQSTSIGIKN 739
           ++ EEEEEEEEA      EDL+ + E   +   + E E+    K  D S  +S+ I N
Sbjct: 447 EEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISN 504


>gi|215422388 death-domain associated protein isoform a [Homo
           sapiens]
          Length = 740

 Score = 30.8 bits (68), Expect = 8.6
 Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 4/58 (6%)

Query: 686 QQGEEEEEEEEAF----YEDLDDILESITNRMIKSELEDFELDKSADFSQSTSIGIKN 739
           ++ EEEEEEEEA      EDL+ + E   +   + E E+    K  D S  +S+ I N
Sbjct: 447 EEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISN 504


>gi|215422366 death-domain associated protein isoform b [Homo
           sapiens]
          Length = 752

 Score = 30.8 bits (68), Expect = 8.6
 Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 4/58 (6%)

Query: 686 QQGEEEEEEEEAF----YEDLDDILESITNRMIKSELEDFELDKSADFSQSTSIGIKN 739
           ++ EEEEEEEEA      EDL+ + E   +   + E E+    K  D S  +S+ I N
Sbjct: 459 EEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISN 516


>gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo
            sapiens]
          Length = 5033

 Score = 30.8 bits (68), Expect = 8.6
 Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 9/75 (12%)

Query: 661  QEPLDYLLCCIQHCLAWYKNTVIPLQQGEEEEEEEEAFYEDLDDILESITNRMIKSELED 720
            Q+ LD+    + HC        I L   EEE EEE      L  +LE +  R++K + E 
Sbjct: 2029 QDLLDFHQDLLAHC-------GIQLDGEEEEPEEETTLGSRLMSLLEKV--RLVKKKEEK 2079

Query: 721  FELDKSADFSQSTSI 735
             E ++SA+ S+  S+
Sbjct: 2080 PEEERSAEESKPRSL 2094


>gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo
            sapiens]
          Length = 5038

 Score = 30.8 bits (68), Expect = 8.6
 Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 9/75 (12%)

Query: 661  QEPLDYLLCCIQHCLAWYKNTVIPLQQGEEEEEEEEAFYEDLDDILESITNRMIKSELED 720
            Q+ LD+    + HC        I L   EEE EEE      L  +LE +  R++K + E 
Sbjct: 2029 QDLLDFHQDLLAHC-------GIQLDGEEEEPEEETTLGSRLMSLLEKV--RLVKKKEEK 2079

Query: 721  FELDKSADFSQSTSI 735
             E ++SA+ S+  S+
Sbjct: 2080 PEEERSAEESKPRSL 2094


>gi|23957698 luman-recruiting factor [Homo sapiens]
          Length = 639

 Score = 30.8 bits (68), Expect = 8.6
 Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 6/51 (11%)

Query: 685 LQQGEEEEEEEEAFYEDLDDILESITNRMIKSELEDFELDKSADFSQSTSI 735
           L + EEEEEEEE + +D DD +    +         +E D   D  + TSI
Sbjct: 379 LSENEEEEEEEEDYEDDKDDDISDTFSE------PGYENDSVEDLKEVTSI 423


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,389,205
Number of Sequences: 37866
Number of extensions: 1773051
Number of successful extensions: 7866
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 7775
Number of HSP's gapped (non-prelim): 114
length of query: 1268
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1154
effective length of database: 13,930,794
effective search space: 16076136276
effective search space used: 16076136276
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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