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Search of human proteins with 7710129
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7710129 LIM domain only 6 [Homo sapiens]
(615 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7710129 LIM domain only 6 [Homo sapiens] 1326 0.0
gi|38524620 prickle-like 2 [Homo sapiens] 545 e-155
gi|222136684 prickle homolog 1 [Homo sapiens] 484 e-136
gi|222136682 prickle homolog 1 [Homo sapiens] 484 e-136
gi|222136680 prickle homolog 1 [Homo sapiens] 484 e-136
gi|222136678 prickle homolog 1 [Homo sapiens] 484 e-136
gi|7661666 testin isoform 1 [Homo sapiens] 288 8e-78
gi|23238188 testin isoform 2 [Homo sapiens] 288 8e-78
gi|118722347 over-expressed breast tumor protein [Homo sapiens] 216 6e-56
gi|7657309 LIM and cysteine-rich domains 1 [Homo sapiens] 196 7e-50
gi|54112385 four and a half LIM domains 3 [Homo sapiens] 102 1e-21
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens] 100 3e-21
gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens] 100 3e-21
gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens] 100 3e-21
gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens] 100 3e-21
gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens] 100 3e-21
gi|87159836 four and a half LIM domains 2 [Homo sapiens] 97 3e-20
gi|87159834 four and a half LIM domains 2 [Homo sapiens] 97 3e-20
gi|42403575 four and a half LIM domains 2 [Homo sapiens] 97 3e-20
gi|87159832 four and a half LIM domains 2 [Homo sapiens] 97 3e-20
gi|109638745 transforming growth factor beta 1 induced transcrip... 95 2e-19
gi|21361591 transforming growth factor beta 1 induced transcript... 95 2e-19
gi|170932518 paxillin isoform 3 [Homo sapiens] 92 1e-18
gi|170932516 paxillin isoform 2 [Homo sapiens] 92 1e-18
gi|170932514 paxillin isoform 1 [Homo sapiens] 92 1e-18
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens] 91 3e-18
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 91 3e-18
gi|221316659 leupaxin isoform 1 [Homo sapiens] 91 4e-18
gi|4758670 leupaxin isoform 2 [Homo sapiens] 91 4e-18
gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens] 90 5e-18
>gi|7710129 LIM domain only 6 [Homo sapiens]
Length = 615
Score = 1326 bits (3432), Expect = 0.0
Identities = 615/615 (100%), Positives = 615/615 (100%)
Query: 1 MFARGSRRRRSGRAPPEAEDPDRGQPCNSCREQCPGFLLHGWRKICQHCKCPREEHAVHA 60
MFARGSRRRRSGRAPPEAEDPDRGQPCNSCREQCPGFLLHGWRKICQHCKCPREEHAVHA
Sbjct: 1 MFARGSRRRRSGRAPPEAEDPDRGQPCNSCREQCPGFLLHGWRKICQHCKCPREEHAVHA 60
Query: 61 VPVDLERIMCRLISDFQRHSISDDDSGCASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYV 120
VPVDLERIMCRLISDFQRHSISDDDSGCASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYV
Sbjct: 61 VPVDLERIMCRLISDFQRHSISDDDSGCASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYV 120
Query: 121 NSPGEKYRIKQLLHQLPPHDSEAQYCTALEEEEKKELRAFSQQRKRENLGRGIVRIFPVT 180
NSPGEKYRIKQLLHQLPPHDSEAQYCTALEEEEKKELRAFSQQRKRENLGRGIVRIFPVT
Sbjct: 121 NSPGEKYRIKQLLHQLPPHDSEAQYCTALEEEEKKELRAFSQQRKRENLGRGIVRIFPVT 180
Query: 181 ITGAICEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCG 240
ITGAICEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCG
Sbjct: 181 ITGAICEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCG 240
Query: 241 RHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCC 300
RHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCC
Sbjct: 241 RHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCC 300
Query: 301 ACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLI 360
ACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLI
Sbjct: 301 ACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLI 360
Query: 361 FCSRACSLGSEPTAPGPSRRSWSAGPVTAPLAASTASFSAVKGASETTTKGTSTELAPAT 420
FCSRACSLGSEPTAPGPSRRSWSAGPVTAPLAASTASFSAVKGASETTTKGTSTELAPAT
Sbjct: 361 FCSRACSLGSEPTAPGPSRRSWSAGPVTAPLAASTASFSAVKGASETTTKGTSTELAPAT 420
Query: 421 GPEEPSRFLRGAPHRHSMPELGLRSVPEPPPESPGQPNLRPDDSAFGRQSTPRVSFRDPL 480
GPEEPSRFLRGAPHRHSMPELGLRSVPEPPPESPGQPNLRPDDSAFGRQSTPRVSFRDPL
Sbjct: 421 GPEEPSRFLRGAPHRHSMPELGLRSVPEPPPESPGQPNLRPDDSAFGRQSTPRVSFRDPL 480
Query: 481 VSEGGPRRTLSAPPAQRRRPRSPPPRAPSRRRHHHHNHHHHHNRHPSRRRHYQCDAGSGS 540
VSEGGPRRTLSAPPAQRRRPRSPPPRAPSRRRHHHHNHHHHHNRHPSRRRHYQCDAGSGS
Sbjct: 481 VSEGGPRRTLSAPPAQRRRPRSPPPRAPSRRRHHHHNHHHHHNRHPSRRRHYQCDAGSGS 540
Query: 541 DSESCSSSPSSSSSESSEDDGFFLGERIPLPPHLCRPMPAQDTAMETFNSPSLSLPRDSR 600
DSESCSSSPSSSSSESSEDDGFFLGERIPLPPHLCRPMPAQDTAMETFNSPSLSLPRDSR
Sbjct: 541 DSESCSSSPSSSSSESSEDDGFFLGERIPLPPHLCRPMPAQDTAMETFNSPSLSLPRDSR 600
Query: 601 AGMPRQARDKNCIVA 615
AGMPRQARDKNCIVA
Sbjct: 601 AGMPRQARDKNCIVA 615
>gi|38524620 prickle-like 2 [Homo sapiens]
Length = 844
Score = 545 bits (1405), Expect = e-155
Identities = 234/321 (72%), Positives = 276/321 (85%)
Query: 58 VHAVPVDLERIMCRLISDFQRHSISDDDSGCASEEYAWVPPGLKPEQVYQFFSCLPEDKV 117
V +P+++E+ + +L+ DFQR+S SDDDSGCA EEYAWVPPGLKPEQV+Q++SCLPE+KV
Sbjct: 2 VTVMPLEMEKTISKLMFDFQRNSTSDDDSGCALEEYAWVPPGLKPEQVHQYYSCLPEEKV 61
Query: 118 PYVNSPGEKYRIKQLLHQLPPHDSEAQYCTALEEEEKKELRAFSQQRKRENLGRGIVRIF 177
PYVNSPGEK RIKQLLHQLPPHD+E +YC +L+EEEK+EL+ FS QRKRENLGRG VR F
Sbjct: 62 PYVNSPGEKLRIKQLLHQLPPHDNEVRYCNSLDEEEKRELKLFSSQRKRENLGRGNVRPF 121
Query: 178 PVTITGAICEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKV 237
PVT+TGAICE+CG QI GGDIAVFASRAG G CWHP CFVCT C ELLVDLIYFY GK+
Sbjct: 122 PVTMTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKI 181
Query: 238 YCGRHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRP 297
YCGRHHAECL+PRC ACDEIIF+ ECTEAEGRHWHM HFCCFECE LGGQRY+M++ RP
Sbjct: 182 YCGRHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRP 241
Query: 298 HCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRR 357
+CC C+E+ +AEYCD C +HIG+DQGQM Y+GQHWHA++ CFCC+ C ++LLGRPFLP++
Sbjct: 242 YCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQ 301
Query: 358 GLIFCSRACSLGSEPTAPGPS 378
G IFCSRACS G +P S
Sbjct: 302 GQIFCSRACSAGEDPNGSDSS 322
Score = 36.2 bits (82), Expect = 0.091
Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 10/70 (14%)
Query: 552 SSSESSEDDGFFLGERIPLPPHLCRPMPAQDTAMETFNSPSLSLPRDSRAG------MPR 605
SSS S+++G+FLGE IP P L D + ++ S LP+ S G +
Sbjct: 779 SSSSESDNEGYFLGEPIPQPARL--RYVTSDELLHKYS--SYGLPKSSTLGGRGQLHSRK 834
Query: 606 QARDKNCIVA 615
+ + KNCI++
Sbjct: 835 RQKSKNCIIS 844
>gi|222136684 prickle homolog 1 [Homo sapiens]
Length = 831
Score = 484 bits (1245), Expect = e-136
Identities = 207/318 (65%), Positives = 255/318 (80%)
Query: 61 VPVDLERIMCRLISDFQRHSISDDDSGCASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYV 120
+P+++E M +L QR S SDDDSGCA EEYAWVPPGL+PEQ+ +F+CLPE+KVPYV
Sbjct: 1 MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV 60
Query: 121 NSPGEKYRIKQLLHQLPPHDSEAQYCTALEEEEKKELRAFSQQRKRENLGRGIVRIFPVT 180
NSPGEK+RIKQLL+QLPPHD+E +YC +L EEEKKEL+ FS QRK+E LGRG +++
Sbjct: 61 NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA 120
Query: 181 ITGAICEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCG 240
+ A+CE+CG +I GG++AVFASRAG G CWHP CFVC TC ELLVDLIYFY GK++CG
Sbjct: 121 VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
Query: 241 RHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCC 300
RHHAE L+PRC ACDEIIF+ ECTEAEGRHWHM HFCC ECE LGGQRY+M+ RP CC
Sbjct: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
Query: 301 ACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLI 360
C+E+ +AEYC+ CGEHIG+D QM Y+GQHWHA++ CF C++C +LLG PFLP++G I
Sbjct: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
Query: 361 FCSRACSLGSEPTAPGPS 378
+CS+ CSLG + A S
Sbjct: 301 YCSKTCSLGEDVHASDSS 318
Score = 40.0 bits (92), Expect = 0.006
Identities = 32/85 (37%), Positives = 46/85 (54%), Gaps = 17/85 (20%)
Query: 539 GSDSESCSSSPSSSSSESSEDDGFFLGERIPLPPHLCRPMPAQDTAMET--FNSPSLSLP 596
G D +S SS SSSS SE++G+FLG+ IP P RP Q A T +SP +LP
Sbjct: 756 GEDDDSWCSS--SSSSSDSEEEGYFLGQPIPQP----RP---QRFAYYTDDLSSPPSALP 806
Query: 597 ------RDSRAGMPRQARDKNCIVA 615
R +++ + + KNCI++
Sbjct: 807 TPQFGQRTTKSKKKKGHKGKNCIIS 831
>gi|222136682 prickle homolog 1 [Homo sapiens]
Length = 831
Score = 484 bits (1245), Expect = e-136
Identities = 207/318 (65%), Positives = 255/318 (80%)
Query: 61 VPVDLERIMCRLISDFQRHSISDDDSGCASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYV 120
+P+++E M +L QR S SDDDSGCA EEYAWVPPGL+PEQ+ +F+CLPE+KVPYV
Sbjct: 1 MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV 60
Query: 121 NSPGEKYRIKQLLHQLPPHDSEAQYCTALEEEEKKELRAFSQQRKRENLGRGIVRIFPVT 180
NSPGEK+RIKQLL+QLPPHD+E +YC +L EEEKKEL+ FS QRK+E LGRG +++
Sbjct: 61 NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA 120
Query: 181 ITGAICEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCG 240
+ A+CE+CG +I GG++AVFASRAG G CWHP CFVC TC ELLVDLIYFY GK++CG
Sbjct: 121 VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
Query: 241 RHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCC 300
RHHAE L+PRC ACDEIIF+ ECTEAEGRHWHM HFCC ECE LGGQRY+M+ RP CC
Sbjct: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
Query: 301 ACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLI 360
C+E+ +AEYC+ CGEHIG+D QM Y+GQHWHA++ CF C++C +LLG PFLP++G I
Sbjct: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
Query: 361 FCSRACSLGSEPTAPGPS 378
+CS+ CSLG + A S
Sbjct: 301 YCSKTCSLGEDVHASDSS 318
Score = 40.0 bits (92), Expect = 0.006
Identities = 32/85 (37%), Positives = 46/85 (54%), Gaps = 17/85 (20%)
Query: 539 GSDSESCSSSPSSSSSESSEDDGFFLGERIPLPPHLCRPMPAQDTAMET--FNSPSLSLP 596
G D +S SS SSSS SE++G+FLG+ IP P RP Q A T +SP +LP
Sbjct: 756 GEDDDSWCSS--SSSSSDSEEEGYFLGQPIPQP----RP---QRFAYYTDDLSSPPSALP 806
Query: 597 ------RDSRAGMPRQARDKNCIVA 615
R +++ + + KNCI++
Sbjct: 807 TPQFGQRTTKSKKKKGHKGKNCIIS 831
>gi|222136680 prickle homolog 1 [Homo sapiens]
Length = 831
Score = 484 bits (1245), Expect = e-136
Identities = 207/318 (65%), Positives = 255/318 (80%)
Query: 61 VPVDLERIMCRLISDFQRHSISDDDSGCASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYV 120
+P+++E M +L QR S SDDDSGCA EEYAWVPPGL+PEQ+ +F+CLPE+KVPYV
Sbjct: 1 MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV 60
Query: 121 NSPGEKYRIKQLLHQLPPHDSEAQYCTALEEEEKKELRAFSQQRKRENLGRGIVRIFPVT 180
NSPGEK+RIKQLL+QLPPHD+E +YC +L EEEKKEL+ FS QRK+E LGRG +++
Sbjct: 61 NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA 120
Query: 181 ITGAICEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCG 240
+ A+CE+CG +I GG++AVFASRAG G CWHP CFVC TC ELLVDLIYFY GK++CG
Sbjct: 121 VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
Query: 241 RHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCC 300
RHHAE L+PRC ACDEIIF+ ECTEAEGRHWHM HFCC ECE LGGQRY+M+ RP CC
Sbjct: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
Query: 301 ACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLI 360
C+E+ +AEYC+ CGEHIG+D QM Y+GQHWHA++ CF C++C +LLG PFLP++G I
Sbjct: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
Query: 361 FCSRACSLGSEPTAPGPS 378
+CS+ CSLG + A S
Sbjct: 301 YCSKTCSLGEDVHASDSS 318
Score = 40.0 bits (92), Expect = 0.006
Identities = 32/85 (37%), Positives = 46/85 (54%), Gaps = 17/85 (20%)
Query: 539 GSDSESCSSSPSSSSSESSEDDGFFLGERIPLPPHLCRPMPAQDTAMET--FNSPSLSLP 596
G D +S SS SSSS SE++G+FLG+ IP P RP Q A T +SP +LP
Sbjct: 756 GEDDDSWCSS--SSSSSDSEEEGYFLGQPIPQP----RP---QRFAYYTDDLSSPPSALP 806
Query: 597 ------RDSRAGMPRQARDKNCIVA 615
R +++ + + KNCI++
Sbjct: 807 TPQFGQRTTKSKKKKGHKGKNCIIS 831
>gi|222136678 prickle homolog 1 [Homo sapiens]
Length = 831
Score = 484 bits (1245), Expect = e-136
Identities = 207/318 (65%), Positives = 255/318 (80%)
Query: 61 VPVDLERIMCRLISDFQRHSISDDDSGCASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYV 120
+P+++E M +L QR S SDDDSGCA EEYAWVPPGL+PEQ+ +F+CLPE+KVPYV
Sbjct: 1 MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV 60
Query: 121 NSPGEKYRIKQLLHQLPPHDSEAQYCTALEEEEKKELRAFSQQRKRENLGRGIVRIFPVT 180
NSPGEK+RIKQLL+QLPPHD+E +YC +L EEEKKEL+ FS QRK+E LGRG +++
Sbjct: 61 NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA 120
Query: 181 ITGAICEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCG 240
+ A+CE+CG +I GG++AVFASRAG G CWHP CFVC TC ELLVDLIYFY GK++CG
Sbjct: 121 VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
Query: 241 RHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCC 300
RHHAE L+PRC ACDEIIF+ ECTEAEGRHWHM HFCC ECE LGGQRY+M+ RP CC
Sbjct: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
Query: 301 ACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLI 360
C+E+ +AEYC+ CGEHIG+D QM Y+GQHWHA++ CF C++C +LLG PFLP++G I
Sbjct: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
Query: 361 FCSRACSLGSEPTAPGPS 378
+CS+ CSLG + A S
Sbjct: 301 YCSKTCSLGEDVHASDSS 318
Score = 40.0 bits (92), Expect = 0.006
Identities = 32/85 (37%), Positives = 46/85 (54%), Gaps = 17/85 (20%)
Query: 539 GSDSESCSSSPSSSSSESSEDDGFFLGERIPLPPHLCRPMPAQDTAMET--FNSPSLSLP 596
G D +S SS SSSS SE++G+FLG+ IP P RP Q A T +SP +LP
Sbjct: 756 GEDDDSWCSS--SSSSSDSEEEGYFLGQPIPQP----RP---QRFAYYTDDLSSPPSALP 806
Query: 597 ------RDSRAGMPRQARDKNCIVA 615
R +++ + + KNCI++
Sbjct: 807 TPQFGQRTTKSKKKKGHKGKNCIIS 831
>gi|7661666 testin isoform 1 [Homo sapiens]
Length = 421
Score = 288 bits (738), Expect = 8e-78
Identities = 149/398 (37%), Positives = 205/398 (51%), Gaps = 55/398 (13%)
Query: 24 GQPCNSCREQCPGFLLHGWRKICQHCKCPREEHAVHAVPVDLERI------------MCR 71
G PC C+E+C GF LH WRKIC++CKC +EEH V + ++ + +
Sbjct: 19 GAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEEDRKVGKLFEDTKYTTLIAK 78
Query: 72 LISD----FQRHSISDDDSGCASEE-------YAWVPPGLKPEQVYQFFSCLPEDKVPYV 120
L SD ++R+ + + A + Y W PP Q+ LP++K P
Sbjct: 79 LKSDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQALARQYMQMLPKEKQPVA 138
Query: 121 NSPGEKYRIKQLLHQLPPHDSEAQYCTALEEEEKKELRAFSQQRKRENLGRGIVRI---- 176
S G +YR KQL QLP HD + C L E KE+ F ++ K E LG G V++
Sbjct: 139 GSEGAQYRKKQLAKQLPAHDQDPSKCHELSPREVKEMEQFVKKYKSEALGVGDVKLPCEM 198
Query: 177 ----------------FPVTI------------TGAICEECGKQIGGGDIAVFASRAGLG 208
P + T C C + GD A++A RAG
Sbjct: 199 DAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHKRTQYSCYCCKLSMKEGDPAIYAERAGYD 258
Query: 209 ACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAECLRPRCQACDEIIFSPECTEAEG 268
WHP CFVC+TC ELLVD+IYF+ K+YCGRH+ + +PRC CDE+IFS E T+AE
Sbjct: 259 KLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAEN 318
Query: 269 RHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYE 328
++WH+ HFCCF+C++ L G+ YVM +P C CY HA C GC I + ++ Y
Sbjct: 319 QNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYN 378
Query: 329 GQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFCSRAC 366
WHAS CF CS C + L+G+ F+P G++FCS C
Sbjct: 379 NFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVEC 416
>gi|23238188 testin isoform 2 [Homo sapiens]
Length = 412
Score = 288 bits (738), Expect = 8e-78
Identities = 149/398 (37%), Positives = 205/398 (51%), Gaps = 55/398 (13%)
Query: 24 GQPCNSCREQCPGFLLHGWRKICQHCKCPREEHAVHAVPVDLERI------------MCR 71
G PC C+E+C GF LH WRKIC++CKC +EEH V + ++ + +
Sbjct: 10 GAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEEDRKVGKLFEDTKYTTLIAK 69
Query: 72 LISD----FQRHSISDDDSGCASEE-------YAWVPPGLKPEQVYQFFSCLPEDKVPYV 120
L SD ++R+ + + A + Y W PP Q+ LP++K P
Sbjct: 70 LKSDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQALARQYMQMLPKEKQPVA 129
Query: 121 NSPGEKYRIKQLLHQLPPHDSEAQYCTALEEEEKKELRAFSQQRKRENLGRGIVRI---- 176
S G +YR KQL QLP HD + C L E KE+ F ++ K E LG G V++
Sbjct: 130 GSEGAQYRKKQLAKQLPAHDQDPSKCHELSPREVKEMEQFVKKYKSEALGVGDVKLPCEM 189
Query: 177 ----------------FPVTI------------TGAICEECGKQIGGGDIAVFASRAGLG 208
P + T C C + GD A++A RAG
Sbjct: 190 DAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHKRTQYSCYCCKLSMKEGDPAIYAERAGYD 249
Query: 209 ACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAECLRPRCQACDEIIFSPECTEAEG 268
WHP CFVC+TC ELLVD+IYF+ K+YCGRH+ + +PRC CDE+IFS E T+AE
Sbjct: 250 KLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAEN 309
Query: 269 RHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYE 328
++WH+ HFCCF+C++ L G+ YVM +P C CY HA C GC I + ++ Y
Sbjct: 310 QNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYN 369
Query: 329 GQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFCSRAC 366
WHAS CF CS C + L+G+ F+P G++FCS C
Sbjct: 370 NFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVEC 407
>gi|118722347 over-expressed breast tumor protein [Homo sapiens]
Length = 384
Score = 216 bits (549), Expect = 6e-56
Identities = 109/243 (44%), Positives = 143/243 (58%), Gaps = 9/243 (3%)
Query: 82 SDDDSGCASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYVNSPGEKYRIKQLLHQLPPHDS 141
SD DSG E P + CL ++ P N G ++ LL QLPP D
Sbjct: 26 SDSDSGHLPGEDPEDTHAQGPAVLSLGSLCLDTNQAP--NWTG----LQTLLQQLPPQDI 79
Query: 142 EAQYCTALEEEEKKELRAFSQQRKRENLGRGIVRIFPVTITGAICEECGKQIGGGDIAVF 201
+ +YC AL EEE+ EL+ F +RK+E LG+G+ R+ + G CE+C + + G+ VF
Sbjct: 80 DERYCLALGEEERAELQLFCARRKQEALGQGVARLVLPKLEGHTCEKCRELLKPGEYGVF 139
Query: 202 ASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAECLRPRCQACDEIIFSP 261
A+RAG CWH CF C C + L++LIYFYH G++YCGRHHAE LRPRC ACD++IFS
Sbjct: 140 AARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFSW 199
Query: 262 ECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLD 321
CTEAEG+ WH +HFCC +C LGG RY + P C +C+E R Y D G
Sbjct: 200 RCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFENR---YSDAGSSWAGAL 256
Query: 322 QGQ 324
+GQ
Sbjct: 257 EGQ 259
Score = 35.4 bits (80), Expect = 0.16
Identities = 63/249 (25%), Positives = 90/249 (36%), Gaps = 36/249 (14%)
Query: 326 AYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFCSRACSLGSEPTAPGPSRRSWSAG 385
A E + WH CF C CG+AL+ + G ++C R + P P + +S
Sbjct: 143 AGEQRCWHQP--CFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFSWR 200
Query: 386 PVTAPLAASTASFSAVKGASETTTKGTSTELAPATGPEEPSRFLRGAPHRHSMPELGLRS 445
A + + + G P P PS F +R+S
Sbjct: 201 CTEAEGQRWHENHFCCQDCAGPL--GGGRYALPGGSPCCPSCF----ENRYSDAGSSWAG 254
Query: 446 VPEPPPESPGQPNLRPD--DSAFGRQSTPRVSF---RDPLVSEGGPRRTLSAPPAQRRRP 500
E GQ L D GR T S R L + GG S+ QR P
Sbjct: 255 ALE------GQAFLGETGLDRTEGRDQTSVNSATLSRTLLAAAGG-----SSLQTQRGLP 303
Query: 501 RSPPPRAPSRRRHHHHNHHHHHNRHPSRRRHYQCDAGSGSDSESCSSSPSSSSSESSEDD 560
S P + + ++ + + QC + D + S SSSS+S E +
Sbjct: 304 GSSPQQ-----------ENRPGDKAEAPKGQEQCRLETIRDPKDTPFSTCSSSSDS-EPE 351
Query: 561 GFFLGERIP 569
GFFLGER+P
Sbjct: 352 GFFLGERLP 360
>gi|7657309 LIM and cysteine-rich domains 1 [Homo sapiens]
Length = 365
Score = 196 bits (497), Expect = 7e-50
Identities = 111/343 (32%), Positives = 157/343 (45%), Gaps = 58/343 (16%)
Query: 23 RGQPCNSCREQCPGFLLHGWRKICQHCKCPREEHAVHAVPVDLERIMCRLISDFQRHSIS 82
RG C C+ C GF H WRKIC+ CKC +E+H + + D +R + RL+ D + +++
Sbjct: 24 RGVACLGCKGTCSGFEPHSWRKICKSCKCSQEDHCLTSDLED-DRKIGRLLMDSKYSTLT 82
Query: 83 -------------------------DDDSGCASEEYAWVPPGLKPEQVYQFFSCLPEDKV 117
D + Y W PPG+ + Q+ +P++K
Sbjct: 83 ARVKGGDGIRIYKRNRMIMTNPIATGKDPTFDTITYEWAPPGVTQKLGLQYMELIPKEKQ 142
Query: 118 PYVNSPGEKYRIKQLLHQLPPHDSEAQYCTALEEEEKKELRAFSQQRKRENLGRGIVRI- 176
P + G YR +QL+HQLP +D + C L E E K + F +Q K E LG G V +
Sbjct: 143 PVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGLLENELKLMEEFVKQYKSEALGVGEVALP 202
Query: 177 ---------------------FPVTITGA----------ICEECGKQIGGGDIAVFASRA 205
T G+ +CE C V++ RA
Sbjct: 203 GQGGLPKEEGKQQEKPEGAETTAATTNGSLSDPSKEVEYVCELCKGAAPPDSPVVYSDRA 262
Query: 206 GLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAECLRPRCQACDEIIFSPECTE 265
G WHP CFVC C E LVDLIYF+ G +CGRH+ E LRPRC CDEIIF+ +
Sbjct: 263 GYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQR 322
Query: 266 AEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEARHA 308
E WH HF C CE L G+ Y++ + + C C +++ +
Sbjct: 323 VEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCSKSKRS 365
>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
Length = 280
Score = 102 bits (254), Expect = 1e-21
Identities = 55/184 (29%), Positives = 86/184 (46%), Gaps = 10/184 (5%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAE 245
C CG+ + G + G WH CF+C+ C++ L + G YC +
Sbjct: 101 CSACGETVMPGSRKLEYG----GQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYEN 156
Query: 246 CLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEA 305
PRC C + + T + + WH + C C+ L GQ++ R P+C AC+
Sbjct: 157 KFAPRCARCSKTLTQGGVTYRD-QPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGE 215
Query: 306 RHAEYCDGCGEHI-GLDQGQ-MAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFCS 363
A C C I GL G+ +++E +HWH CF C+RC +L+G+ F+P + C
Sbjct: 216 LFAPKCSSCKRPIVGLGGGKYVSFEDRHWH--HNCFSCARCSTSLVGQGFVPDGDQVLC- 272
Query: 364 RACS 367
+ CS
Sbjct: 273 QGCS 276
Score = 85.5 bits (210), Expect = 1e-16
Identities = 52/178 (29%), Positives = 72/178 (40%), Gaps = 9/178 (5%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAE 245
C EC + IG +F +H CF C CQ L D + ++ C +
Sbjct: 40 CAECQQLIGHDSRELFYEDRH----FHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCS 95
Query: 246 CLRPRCQACDEIIF-SPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYE 304
+C AC E + E G+ WH F C CE LG + +V + +C CYE
Sbjct: 96 AFSSQCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYE 155
Query: 305 ARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFC 362
+ A C C + L QG + Y Q WH C C+ C L G+ F R +C
Sbjct: 156 NKFAPRCARCSK--TLTQGGVTYRDQPWHR--ECLVCTGCQTPLAGQQFTSRDEDPYC 209
Score = 79.3 bits (194), Expect = 9e-15
Identities = 45/151 (29%), Positives = 65/151 (43%), Gaps = 5/151 (3%)
Query: 214 QCFVCTTCQELLVDLIYFYHVGKVYCGRHHAECLRPRCQACDEIIFSPECTEA--EGRHW 271
+ F C C E L Y YC + C C ++I + E E RH+
Sbjct: 3 ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLI-GHDSRELFYEDRHF 61
Query: 272 HMDHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQH 331
H F C C+ SL + + + S C CY + + C CGE + ++ Y GQ
Sbjct: 62 HEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQT 121
Query: 332 WHASDRCFCCSRCGRALLGRPFLPRRGLIFC 362
WH + CF CS C + L R F+P +G +C
Sbjct: 122 WH--EHCFLCSGCEQPLGSRSFVPDKGAHYC 150
Score = 74.3 bits (181), Expect = 3e-13
Identities = 38/111 (34%), Positives = 54/111 (48%), Gaps = 10/111 (9%)
Query: 274 DHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWH 333
+ F C +C SL G++Y+ S P+C CY+ A C C + IG D ++ YE +H+H
Sbjct: 3 ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFH 62
Query: 334 ASDRCFCCSRCGRALLGRPFLPRRGLIFC--------SRACSLGSEPTAPG 376
+ CF C RC R+L PF + + C S CS E PG
Sbjct: 63 --EGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPG 111
Score = 61.2 bits (147), Expect = 3e-09
Identities = 36/123 (29%), Positives = 47/123 (38%), Gaps = 9/123 (7%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAE 245
C C K + G + WH +C VCT CQ L + YC E
Sbjct: 162 CARCSKTLTQGGVTYRDQP------WHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGE 215
Query: 246 CLRPRCQACDEIIFS---PECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCAC 302
P+C +C I + E RHWH + F C C SL GQ +V + C C
Sbjct: 216 LFAPKCSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGC 275
Query: 303 YEA 305
+A
Sbjct: 276 SQA 278
>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 100 bits (250), Expect = 3e-21
Identities = 57/180 (31%), Positives = 81/180 (45%), Gaps = 10/180 (5%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAE 245
C+ C K I GD V G WH CF C+ C++++ +F YC H
Sbjct: 101 CKGCFKAIVAGDQNVEYK----GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHET 156
Query: 246 CLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEA 305
C C++ I S T + + WH D F C C L GQR+ + + +C CY+
Sbjct: 157 KFAKHCVKCNKAITSGGITYQD-QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
Query: 306 RHAEYCDGCGEHI---GLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFC 362
A+ C GC I G +AYEGQ WH D CF C +C L + F+ + ++C
Sbjct: 216 FVAKKCAGCKNPITGFGKGSSVVAYEGQSWH--DYCFHCKKCSVNLANKRFVFHQEQVYC 273
Score = 90.1 bits (222), Expect = 5e-18
Identities = 49/178 (27%), Positives = 74/178 (41%), Gaps = 9/178 (5%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAE 245
C EC K IG V WH CF C C L + + K+ C +
Sbjct: 40 CVECRKPIGADSKEVHYKNR----FWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 95
Query: 246 CLRPRCQAC-DEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYE 304
P+C+ C I+ + E +G WH D F C C+ +G + + +C C+E
Sbjct: 96 EDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHE 155
Query: 305 ARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFC 362
+ A++C C + + G + Y+ Q WHA CF C C + L G+ F +C
Sbjct: 156 TKFAKHCVKCNK--AITSGGITYQDQPWHAD--CFVCVTCSKKLAGQRFTAVEDQYYC 209
Score = 62.8 bits (151), Expect = 9e-10
Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 2/103 (1%)
Query: 274 DHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWH 333
+ F C C L G++YV + C C++ A C C + IG D ++ Y+ + WH
Sbjct: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
Query: 334 ASDRCFCCSRCGRALLGRPFLPRRGLIFCSRACSLGSEPTAPG 376
D CF C++C L F+ + I C++ + P G
Sbjct: 63 --DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKG 103
Score = 57.4 bits (137), Expect = 4e-08
Identities = 33/121 (27%), Positives = 47/121 (38%), Gaps = 10/121 (8%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAE 245
C +C K I G I WH CFVC TC + L + + YC +
Sbjct: 162 CVKCNKAITSGGITYQDQP------WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
Query: 246 CLRPRCQACDEIIFS----PECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCA 301
+ +C C I EG+ WH F C +C +L +R+V Q + +C
Sbjct: 216 FVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 275
Query: 302 C 302
C
Sbjct: 276 C 276
Score = 55.8 bits (133), Expect = 1e-07
Identities = 31/125 (24%), Positives = 50/125 (40%), Gaps = 9/125 (7%)
Query: 238 YCGRHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRP 297
+C EC +P E+ + + R WH F C +C L + +V + ++
Sbjct: 35 FCANTCVECRKPIGADSKEVHY-------KNRFWHDTCFRCAKCLHPLANETFVAKDNKI 87
Query: 298 HCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRR 357
C C + C GC + I + Y+G WH CF CS C + + F P+
Sbjct: 88 LCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKD--CFTCSNCKQVIGTGSFFPKG 145
Query: 358 GLIFC 362
+C
Sbjct: 146 EDFYC 150
>gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 100 bits (250), Expect = 3e-21
Identities = 57/180 (31%), Positives = 81/180 (45%), Gaps = 10/180 (5%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAE 245
C+ C K I GD V G WH CF C+ C++++ +F YC H
Sbjct: 101 CKGCFKAIVAGDQNVEYK----GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHET 156
Query: 246 CLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEA 305
C C++ I S T + + WH D F C C L GQR+ + + +C CY+
Sbjct: 157 KFAKHCVKCNKAITSGGITYQD-QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
Query: 306 RHAEYCDGCGEHI---GLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFC 362
A+ C GC I G +AYEGQ WH D CF C +C L + F+ + ++C
Sbjct: 216 FVAKKCAGCKNPITGFGKGSSVVAYEGQSWH--DYCFHCKKCSVNLANKRFVFHQEQVYC 273
Score = 90.1 bits (222), Expect = 5e-18
Identities = 49/178 (27%), Positives = 74/178 (41%), Gaps = 9/178 (5%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAE 245
C EC K IG V WH CF C C L + + K+ C +
Sbjct: 40 CVECRKPIGADSKEVHYKNR----FWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 95
Query: 246 CLRPRCQAC-DEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYE 304
P+C+ C I+ + E +G WH D F C C+ +G + + +C C+E
Sbjct: 96 EDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHE 155
Query: 305 ARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFC 362
+ A++C C + + G + Y+ Q WHA CF C C + L G+ F +C
Sbjct: 156 TKFAKHCVKCNK--AITSGGITYQDQPWHAD--CFVCVTCSKKLAGQRFTAVEDQYYC 209
Score = 62.8 bits (151), Expect = 9e-10
Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 2/103 (1%)
Query: 274 DHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWH 333
+ F C C L G++YV + C C++ A C C + IG D ++ Y+ + WH
Sbjct: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
Query: 334 ASDRCFCCSRCGRALLGRPFLPRRGLIFCSRACSLGSEPTAPG 376
D CF C++C L F+ + I C++ + P G
Sbjct: 63 --DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKG 103
Score = 57.4 bits (137), Expect = 4e-08
Identities = 33/121 (27%), Positives = 47/121 (38%), Gaps = 10/121 (8%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAE 245
C +C K I G I WH CFVC TC + L + + YC +
Sbjct: 162 CVKCNKAITSGGITYQDQP------WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
Query: 246 CLRPRCQACDEIIFS----PECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCA 301
+ +C C I EG+ WH F C +C +L +R+V Q + +C
Sbjct: 216 FVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 275
Query: 302 C 302
C
Sbjct: 276 C 276
Score = 55.8 bits (133), Expect = 1e-07
Identities = 31/125 (24%), Positives = 50/125 (40%), Gaps = 9/125 (7%)
Query: 238 YCGRHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRP 297
+C EC +P E+ + + R WH F C +C L + +V + ++
Sbjct: 35 FCANTCVECRKPIGADSKEVHY-------KNRFWHDTCFRCAKCLHPLANETFVAKDNKI 87
Query: 298 HCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRR 357
C C + C GC + I + Y+G WH CF CS C + + F P+
Sbjct: 88 LCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKD--CFTCSNCKQVIGTGSFFPKG 145
Query: 358 GLIFC 362
+C
Sbjct: 146 EDFYC 150
>gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]
Length = 309
Score = 100 bits (250), Expect = 3e-21
Identities = 57/180 (31%), Positives = 81/180 (45%), Gaps = 10/180 (5%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAE 245
C+ C K I GD V G WH CF C+ C++++ +F YC H
Sbjct: 130 CKGCFKAIVAGDQNVEYK----GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHET 185
Query: 246 CLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEA 305
C C++ I S T + + WH D F C C L GQR+ + + +C CY+
Sbjct: 186 KFAKHCVKCNKAITSGGITYQD-QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 244
Query: 306 RHAEYCDGCGEHI---GLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFC 362
A+ C GC I G +AYEGQ WH D CF C +C L + F+ + ++C
Sbjct: 245 FVAKKCAGCKNPITGFGKGSSVVAYEGQSWH--DYCFHCKKCSVNLANKRFVFHQEQVYC 302
Score = 90.1 bits (222), Expect = 5e-18
Identities = 49/178 (27%), Positives = 74/178 (41%), Gaps = 9/178 (5%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAE 245
C EC K IG V WH CF C C L + + K+ C +
Sbjct: 69 CVECRKPIGADSKEVHYKNR----FWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 124
Query: 246 CLRPRCQAC-DEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYE 304
P+C+ C I+ + E +G WH D F C C+ +G + + +C C+E
Sbjct: 125 EDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHE 184
Query: 305 ARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFC 362
+ A++C C + + G + Y+ Q WHA CF C C + L G+ F +C
Sbjct: 185 TKFAKHCVKCNK--AITSGGITYQDQPWHAD--CFVCVTCSKKLAGQRFTAVEDQYYC 238
Score = 62.8 bits (151), Expect = 9e-10
Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 2/103 (1%)
Query: 274 DHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWH 333
+ F C C L G++YV + C C++ A C C + IG D ++ Y+ + WH
Sbjct: 32 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 91
Query: 334 ASDRCFCCSRCGRALLGRPFLPRRGLIFCSRACSLGSEPTAPG 376
D CF C++C L F+ + I C++ + P G
Sbjct: 92 --DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKG 132
Score = 57.4 bits (137), Expect = 4e-08
Identities = 33/121 (27%), Positives = 47/121 (38%), Gaps = 10/121 (8%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAE 245
C +C K I G I WH CFVC TC + L + + YC +
Sbjct: 191 CVKCNKAITSGGITYQDQP------WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 244
Query: 246 CLRPRCQACDEIIFS----PECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCA 301
+ +C C I EG+ WH F C +C +L +R+V Q + +C
Sbjct: 245 FVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 304
Query: 302 C 302
C
Sbjct: 305 C 305
Score = 55.8 bits (133), Expect = 1e-07
Identities = 31/125 (24%), Positives = 50/125 (40%), Gaps = 9/125 (7%)
Query: 238 YCGRHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRP 297
+C EC +P E+ + + R WH F C +C L + +V + ++
Sbjct: 64 FCANTCVECRKPIGADSKEVHY-------KNRFWHDTCFRCAKCLHPLANETFVAKDNKI 116
Query: 298 HCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRR 357
C C + C GC + I + Y+G WH CF CS C + + F P+
Sbjct: 117 LCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKD--CFTCSNCKQVIGTGSFFPKG 174
Query: 358 GLIFC 362
+C
Sbjct: 175 EDFYC 179
>gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]
Length = 296
Score = 100 bits (250), Expect = 3e-21
Identities = 57/180 (31%), Positives = 81/180 (45%), Gaps = 10/180 (5%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAE 245
C+ C K I GD V G WH CF C+ C++++ +F YC H
Sbjct: 117 CKGCFKAIVAGDQNVEYK----GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHET 172
Query: 246 CLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEA 305
C C++ I S T + + WH D F C C L GQR+ + + +C CY+
Sbjct: 173 KFAKHCVKCNKAITSGGITYQD-QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 231
Query: 306 RHAEYCDGCGEHI---GLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFC 362
A+ C GC I G +AYEGQ WH D CF C +C L + F+ + ++C
Sbjct: 232 FVAKKCAGCKNPITGFGKGSSVVAYEGQSWH--DYCFHCKKCSVNLANKRFVFHQEQVYC 289
Score = 90.1 bits (222), Expect = 5e-18
Identities = 49/178 (27%), Positives = 74/178 (41%), Gaps = 9/178 (5%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAE 245
C EC K IG V WH CF C C L + + K+ C +
Sbjct: 56 CVECRKPIGADSKEVHYKNR----FWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 111
Query: 246 CLRPRCQAC-DEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYE 304
P+C+ C I+ + E +G WH D F C C+ +G + + +C C+E
Sbjct: 112 EDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHE 171
Query: 305 ARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFC 362
+ A++C C + + G + Y+ Q WHA CF C C + L G+ F +C
Sbjct: 172 TKFAKHCVKCNK--AITSGGITYQDQPWHAD--CFVCVTCSKKLAGQRFTAVEDQYYC 225
Score = 62.8 bits (151), Expect = 9e-10
Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 2/103 (1%)
Query: 274 DHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWH 333
+ F C C L G++YV + C C++ A C C + IG D ++ Y+ + WH
Sbjct: 19 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 78
Query: 334 ASDRCFCCSRCGRALLGRPFLPRRGLIFCSRACSLGSEPTAPG 376
D CF C++C L F+ + I C++ + P G
Sbjct: 79 --DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKG 119
Score = 57.4 bits (137), Expect = 4e-08
Identities = 33/121 (27%), Positives = 47/121 (38%), Gaps = 10/121 (8%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAE 245
C +C K I G I WH CFVC TC + L + + YC +
Sbjct: 178 CVKCNKAITSGGITYQDQP------WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 231
Query: 246 CLRPRCQACDEIIFS----PECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCA 301
+ +C C I EG+ WH F C +C +L +R+V Q + +C
Sbjct: 232 FVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 291
Query: 302 C 302
C
Sbjct: 292 C 292
Score = 55.8 bits (133), Expect = 1e-07
Identities = 31/125 (24%), Positives = 50/125 (40%), Gaps = 9/125 (7%)
Query: 238 YCGRHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRP 297
+C EC +P E+ + + R WH F C +C L + +V + ++
Sbjct: 51 FCANTCVECRKPIGADSKEVHY-------KNRFWHDTCFRCAKCLHPLANETFVAKDNKI 103
Query: 298 HCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRR 357
C C + C GC + I + Y+G WH CF CS C + + F P+
Sbjct: 104 LCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKD--CFTCSNCKQVIGTGSFFPKG 161
Query: 358 GLIFC 362
+C
Sbjct: 162 EDFYC 166
>gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 100 bits (250), Expect = 3e-21
Identities = 57/180 (31%), Positives = 81/180 (45%), Gaps = 10/180 (5%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAE 245
C+ C K I GD V G WH CF C+ C++++ +F YC H
Sbjct: 101 CKGCFKAIVAGDQNVEYK----GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHET 156
Query: 246 CLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEA 305
C C++ I S T + + WH D F C C L GQR+ + + +C CY+
Sbjct: 157 KFAKHCVKCNKAITSGGITYQD-QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
Query: 306 RHAEYCDGCGEHI---GLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFC 362
A+ C GC I G +AYEGQ WH D CF C +C L + F+ + ++C
Sbjct: 216 FVAKKCAGCKNPITGFGKGSSVVAYEGQSWH--DYCFHCKKCSVNLANKRFVFHQEQVYC 273
Score = 90.1 bits (222), Expect = 5e-18
Identities = 49/178 (27%), Positives = 74/178 (41%), Gaps = 9/178 (5%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAE 245
C EC K IG V WH CF C C L + + K+ C +
Sbjct: 40 CVECRKPIGADSKEVHYKNR----FWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 95
Query: 246 CLRPRCQAC-DEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYE 304
P+C+ C I+ + E +G WH D F C C+ +G + + +C C+E
Sbjct: 96 EDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHE 155
Query: 305 ARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFC 362
+ A++C C + + G + Y+ Q WHA CF C C + L G+ F +C
Sbjct: 156 TKFAKHCVKCNK--AITSGGITYQDQPWHAD--CFVCVTCSKKLAGQRFTAVEDQYYC 209
Score = 62.8 bits (151), Expect = 9e-10
Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 2/103 (1%)
Query: 274 DHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWH 333
+ F C C L G++YV + C C++ A C C + IG D ++ Y+ + WH
Sbjct: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
Query: 334 ASDRCFCCSRCGRALLGRPFLPRRGLIFCSRACSLGSEPTAPG 376
D CF C++C L F+ + I C++ + P G
Sbjct: 63 --DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKG 103
Score = 57.4 bits (137), Expect = 4e-08
Identities = 33/121 (27%), Positives = 47/121 (38%), Gaps = 10/121 (8%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAE 245
C +C K I G I WH CFVC TC + L + + YC +
Sbjct: 162 CVKCNKAITSGGITYQDQP------WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
Query: 246 CLRPRCQACDEIIFS----PECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCA 301
+ +C C I EG+ WH F C +C +L +R+V Q + +C
Sbjct: 216 FVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 275
Query: 302 C 302
C
Sbjct: 276 C 276
Score = 55.8 bits (133), Expect = 1e-07
Identities = 31/125 (24%), Positives = 50/125 (40%), Gaps = 9/125 (7%)
Query: 238 YCGRHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRP 297
+C EC +P E+ + + R WH F C +C L + +V + ++
Sbjct: 35 FCANTCVECRKPIGADSKEVHY-------KNRFWHDTCFRCAKCLHPLANETFVAKDNKI 87
Query: 298 HCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRR 357
C C + C GC + I + Y+G WH CF CS C + + F P+
Sbjct: 88 LCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKD--CFTCSNCKQVIGTGSFFPKG 145
Query: 358 GLIFC 362
+C
Sbjct: 146 EDFYC 150
>gi|87159836 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 97.4 bits (241), Expect = 3e-20
Identities = 56/186 (30%), Positives = 85/186 (45%), Gaps = 13/186 (6%)
Query: 180 TITGAICEECGKQIGGG--DIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKV 237
T+ CEECGK IG D++ + R WH CF C+ C+ LVD + ++
Sbjct: 34 TLFANTCEECGKPIGCDCKDLS-YKDRH-----WHEACFHCSQCRNSLVDKPFAAKEDQL 87
Query: 238 YCGRHHAECLRPRCQACDEIIF-SPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSR 296
C ++ +CQ C + I E +G WH F C C+ +G + ++ + ++
Sbjct: 88 LCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQ 147
Query: 297 PHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPR 356
C CYE +HA C C + I G + Y Q WH CF C+ C + L G+ F R
Sbjct: 148 NFCVPCYEKQHAMQCVQCKKPI--TTGGVTYREQPWH--KECFVCTACRKQLSGQRFTAR 203
Query: 357 RGLIFC 362
+C
Sbjct: 204 DDFAYC 209
Score = 89.0 bits (219), Expect = 1e-17
Identities = 53/179 (29%), Positives = 82/179 (45%), Gaps = 9/179 (5%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAE 245
C+EC K I G + G+ WH CF+C CQ+ + + + +C + +
Sbjct: 101 CQECKKTIMPGTRKMEYK----GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEK 156
Query: 246 CLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEA 305
+C C + I + T E + WH + F C C L GQR+ R +C C+
Sbjct: 157 QHAMQCVQCKKPITTGGVTYRE-QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCD 215
Query: 306 RHAEYCDGCGEHIGLDQG--QMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFC 362
+A+ C GC I G +++E + WH + CF C +C +L+GR FL R I C
Sbjct: 216 LYAKKCAGCTNPISGLGGTKYISFEERQWH--NDCFNCKKCSLSLVGRGFLTERDDILC 272
Score = 84.3 bits (207), Expect = 3e-16
Identities = 32/90 (35%), Positives = 54/90 (60%), Gaps = 2/90 (2%)
Query: 274 DHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWH 333
+ F C C SL G++Y++R+ P+C C+E A C+ CG+ IG D ++Y+ +HWH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 334 ASDRCFCCSRCGRALLGRPFLPRRGLIFCS 363
+ CF CS+C +L+ +PF + + C+
Sbjct: 63 --EACFHCSQCRNSLVDKPFAAKEDQLLCT 90
Score = 73.9 bits (180), Expect = 4e-13
Identities = 45/160 (28%), Positives = 66/160 (41%), Gaps = 27/160 (16%)
Query: 216 FVCTTCQELLVDLIYFYHVGKVYCGRHHAECLRPRCQACDEIIFSPECTEA--------- 266
F C C E L GK Y R + P C C E +F+ C E
Sbjct: 5 FDCHHCNESLF--------GKKYILREES----PYCVVCFETLFANTCEECGKPIGCDCK 52
Query: 267 ----EGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQ 322
+ RHWH F C +C SL + + ++ + C CY ++ C C + I
Sbjct: 53 DLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGT 112
Query: 323 GQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFC 362
+M Y+G WH + CF C RC + + + F+P+ FC
Sbjct: 113 RKMEYKGSSWH--ETCFICHRCQQPIGTKSFIPKDNQNFC 150
Score = 52.4 bits (124), Expect = 1e-06
Identities = 33/120 (27%), Positives = 47/120 (39%), Gaps = 9/120 (7%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAE 245
C +C K I G + WH +CFVCT C++ L + YC +
Sbjct: 162 CVQCKKPITTGGVTYREQP------WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCD 215
Query: 246 CLRPRCQACDEIIFSPECTEA---EGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCAC 302
+C C I T+ E R WH D F C +C SL G+ ++ + C C
Sbjct: 216 LYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
>gi|87159834 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 97.4 bits (241), Expect = 3e-20
Identities = 56/186 (30%), Positives = 85/186 (45%), Gaps = 13/186 (6%)
Query: 180 TITGAICEECGKQIGGG--DIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKV 237
T+ CEECGK IG D++ + R WH CF C+ C+ LVD + ++
Sbjct: 34 TLFANTCEECGKPIGCDCKDLS-YKDRH-----WHEACFHCSQCRNSLVDKPFAAKEDQL 87
Query: 238 YCGRHHAECLRPRCQACDEIIF-SPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSR 296
C ++ +CQ C + I E +G WH F C C+ +G + ++ + ++
Sbjct: 88 LCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQ 147
Query: 297 PHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPR 356
C CYE +HA C C + I G + Y Q WH CF C+ C + L G+ F R
Sbjct: 148 NFCVPCYEKQHAMQCVQCKKPI--TTGGVTYREQPWH--KECFVCTACRKQLSGQRFTAR 203
Query: 357 RGLIFC 362
+C
Sbjct: 204 DDFAYC 209
Score = 89.0 bits (219), Expect = 1e-17
Identities = 53/179 (29%), Positives = 82/179 (45%), Gaps = 9/179 (5%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAE 245
C+EC K I G + G+ WH CF+C CQ+ + + + +C + +
Sbjct: 101 CQECKKTIMPGTRKMEYK----GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEK 156
Query: 246 CLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEA 305
+C C + I + T E + WH + F C C L GQR+ R +C C+
Sbjct: 157 QHAMQCVQCKKPITTGGVTYRE-QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCD 215
Query: 306 RHAEYCDGCGEHIGLDQG--QMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFC 362
+A+ C GC I G +++E + WH + CF C +C +L+GR FL R I C
Sbjct: 216 LYAKKCAGCTNPISGLGGTKYISFEERQWH--NDCFNCKKCSLSLVGRGFLTERDDILC 272
Score = 84.3 bits (207), Expect = 3e-16
Identities = 32/90 (35%), Positives = 54/90 (60%), Gaps = 2/90 (2%)
Query: 274 DHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWH 333
+ F C C SL G++Y++R+ P+C C+E A C+ CG+ IG D ++Y+ +HWH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 334 ASDRCFCCSRCGRALLGRPFLPRRGLIFCS 363
+ CF CS+C +L+ +PF + + C+
Sbjct: 63 --EACFHCSQCRNSLVDKPFAAKEDQLLCT 90
Score = 73.9 bits (180), Expect = 4e-13
Identities = 45/160 (28%), Positives = 66/160 (41%), Gaps = 27/160 (16%)
Query: 216 FVCTTCQELLVDLIYFYHVGKVYCGRHHAECLRPRCQACDEIIFSPECTEA--------- 266
F C C E L GK Y R + P C C E +F+ C E
Sbjct: 5 FDCHHCNESLF--------GKKYILREES----PYCVVCFETLFANTCEECGKPIGCDCK 52
Query: 267 ----EGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQ 322
+ RHWH F C +C SL + + ++ + C CY ++ C C + I
Sbjct: 53 DLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGT 112
Query: 323 GQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFC 362
+M Y+G WH + CF C RC + + + F+P+ FC
Sbjct: 113 RKMEYKGSSWH--ETCFICHRCQQPIGTKSFIPKDNQNFC 150
Score = 52.4 bits (124), Expect = 1e-06
Identities = 33/120 (27%), Positives = 47/120 (39%), Gaps = 9/120 (7%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAE 245
C +C K I G + WH +CFVCT C++ L + YC +
Sbjct: 162 CVQCKKPITTGGVTYREQP------WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCD 215
Query: 246 CLRPRCQACDEIIFSPECTEA---EGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCAC 302
+C C I T+ E R WH D F C +C SL G+ ++ + C C
Sbjct: 216 LYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
>gi|42403575 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 97.4 bits (241), Expect = 3e-20
Identities = 56/186 (30%), Positives = 85/186 (45%), Gaps = 13/186 (6%)
Query: 180 TITGAICEECGKQIGGG--DIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKV 237
T+ CEECGK IG D++ + R WH CF C+ C+ LVD + ++
Sbjct: 34 TLFANTCEECGKPIGCDCKDLS-YKDRH-----WHEACFHCSQCRNSLVDKPFAAKEDQL 87
Query: 238 YCGRHHAECLRPRCQACDEIIF-SPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSR 296
C ++ +CQ C + I E +G WH F C C+ +G + ++ + ++
Sbjct: 88 LCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQ 147
Query: 297 PHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPR 356
C CYE +HA C C + I G + Y Q WH CF C+ C + L G+ F R
Sbjct: 148 NFCVPCYEKQHAMQCVQCKKPI--TTGGVTYREQPWH--KECFVCTACRKQLSGQRFTAR 203
Query: 357 RGLIFC 362
+C
Sbjct: 204 DDFAYC 209
Score = 89.0 bits (219), Expect = 1e-17
Identities = 53/179 (29%), Positives = 82/179 (45%), Gaps = 9/179 (5%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAE 245
C+EC K I G + G+ WH CF+C CQ+ + + + +C + +
Sbjct: 101 CQECKKTIMPGTRKMEYK----GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEK 156
Query: 246 CLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEA 305
+C C + I + T E + WH + F C C L GQR+ R +C C+
Sbjct: 157 QHAMQCVQCKKPITTGGVTYRE-QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCD 215
Query: 306 RHAEYCDGCGEHIGLDQG--QMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFC 362
+A+ C GC I G +++E + WH + CF C +C +L+GR FL R I C
Sbjct: 216 LYAKKCAGCTNPISGLGGTKYISFEERQWH--NDCFNCKKCSLSLVGRGFLTERDDILC 272
Score = 84.3 bits (207), Expect = 3e-16
Identities = 32/90 (35%), Positives = 54/90 (60%), Gaps = 2/90 (2%)
Query: 274 DHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWH 333
+ F C C SL G++Y++R+ P+C C+E A C+ CG+ IG D ++Y+ +HWH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 334 ASDRCFCCSRCGRALLGRPFLPRRGLIFCS 363
+ CF CS+C +L+ +PF + + C+
Sbjct: 63 --EACFHCSQCRNSLVDKPFAAKEDQLLCT 90
Score = 73.9 bits (180), Expect = 4e-13
Identities = 45/160 (28%), Positives = 66/160 (41%), Gaps = 27/160 (16%)
Query: 216 FVCTTCQELLVDLIYFYHVGKVYCGRHHAECLRPRCQACDEIIFSPECTEA--------- 266
F C C E L GK Y R + P C C E +F+ C E
Sbjct: 5 FDCHHCNESLF--------GKKYILREES----PYCVVCFETLFANTCEECGKPIGCDCK 52
Query: 267 ----EGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQ 322
+ RHWH F C +C SL + + ++ + C CY ++ C C + I
Sbjct: 53 DLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGT 112
Query: 323 GQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFC 362
+M Y+G WH + CF C RC + + + F+P+ FC
Sbjct: 113 RKMEYKGSSWH--ETCFICHRCQQPIGTKSFIPKDNQNFC 150
Score = 52.4 bits (124), Expect = 1e-06
Identities = 33/120 (27%), Positives = 47/120 (39%), Gaps = 9/120 (7%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAE 245
C +C K I G + WH +CFVCT C++ L + YC +
Sbjct: 162 CVQCKKPITTGGVTYREQP------WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCD 215
Query: 246 CLRPRCQACDEIIFSPECTEA---EGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCAC 302
+C C I T+ E R WH D F C +C SL G+ ++ + C C
Sbjct: 216 LYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
>gi|87159832 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 97.4 bits (241), Expect = 3e-20
Identities = 56/186 (30%), Positives = 85/186 (45%), Gaps = 13/186 (6%)
Query: 180 TITGAICEECGKQIGGG--DIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKV 237
T+ CEECGK IG D++ + R WH CF C+ C+ LVD + ++
Sbjct: 34 TLFANTCEECGKPIGCDCKDLS-YKDRH-----WHEACFHCSQCRNSLVDKPFAAKEDQL 87
Query: 238 YCGRHHAECLRPRCQACDEIIF-SPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSR 296
C ++ +CQ C + I E +G WH F C C+ +G + ++ + ++
Sbjct: 88 LCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQ 147
Query: 297 PHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPR 356
C CYE +HA C C + I G + Y Q WH CF C+ C + L G+ F R
Sbjct: 148 NFCVPCYEKQHAMQCVQCKKPI--TTGGVTYREQPWH--KECFVCTACRKQLSGQRFTAR 203
Query: 357 RGLIFC 362
+C
Sbjct: 204 DDFAYC 209
Score = 89.0 bits (219), Expect = 1e-17
Identities = 53/179 (29%), Positives = 82/179 (45%), Gaps = 9/179 (5%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAE 245
C+EC K I G + G+ WH CF+C CQ+ + + + +C + +
Sbjct: 101 CQECKKTIMPGTRKMEYK----GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEK 156
Query: 246 CLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEA 305
+C C + I + T E + WH + F C C L GQR+ R +C C+
Sbjct: 157 QHAMQCVQCKKPITTGGVTYRE-QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCD 215
Query: 306 RHAEYCDGCGEHIGLDQG--QMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFC 362
+A+ C GC I G +++E + WH + CF C +C +L+GR FL R I C
Sbjct: 216 LYAKKCAGCTNPISGLGGTKYISFEERQWH--NDCFNCKKCSLSLVGRGFLTERDDILC 272
Score = 84.3 bits (207), Expect = 3e-16
Identities = 32/90 (35%), Positives = 54/90 (60%), Gaps = 2/90 (2%)
Query: 274 DHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWH 333
+ F C C SL G++Y++R+ P+C C+E A C+ CG+ IG D ++Y+ +HWH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 334 ASDRCFCCSRCGRALLGRPFLPRRGLIFCS 363
+ CF CS+C +L+ +PF + + C+
Sbjct: 63 --EACFHCSQCRNSLVDKPFAAKEDQLLCT 90
Score = 73.9 bits (180), Expect = 4e-13
Identities = 45/160 (28%), Positives = 66/160 (41%), Gaps = 27/160 (16%)
Query: 216 FVCTTCQELLVDLIYFYHVGKVYCGRHHAECLRPRCQACDEIIFSPECTEA--------- 266
F C C E L GK Y R + P C C E +F+ C E
Sbjct: 5 FDCHHCNESLF--------GKKYILREES----PYCVVCFETLFANTCEECGKPIGCDCK 52
Query: 267 ----EGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQ 322
+ RHWH F C +C SL + + ++ + C CY ++ C C + I
Sbjct: 53 DLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGT 112
Query: 323 GQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFC 362
+M Y+G WH + CF C RC + + + F+P+ FC
Sbjct: 113 RKMEYKGSSWH--ETCFICHRCQQPIGTKSFIPKDNQNFC 150
Score = 52.4 bits (124), Expect = 1e-06
Identities = 33/120 (27%), Positives = 47/120 (39%), Gaps = 9/120 (7%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAE 245
C +C K I G + WH +CFVCT C++ L + YC +
Sbjct: 162 CVQCKKPITTGGVTYREQP------WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCD 215
Query: 246 CLRPRCQACDEIIFSPECTEA---EGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCAC 302
+C C I T+ E R WH D F C +C SL G+ ++ + C C
Sbjct: 216 LYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
>gi|109638745 transforming growth factor beta 1 induced transcript 1
isoform 1 [Homo sapiens]
Length = 461
Score = 95.1 bits (235), Expect = 2e-19
Identities = 58/178 (32%), Positives = 72/178 (40%), Gaps = 11/178 (6%)
Query: 185 ICEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHA 244
+C C K I G + LG WHP+ FVC C L +F G +C +
Sbjct: 227 LCGSCNKPIAGQVVTA------LGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYF 280
Query: 245 ECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYE 304
E PRC C++ I T A G HWH +HFCC C G + + R+ RP+C +
Sbjct: 281 ERFSPRCGFCNQPIRHKMVT-ALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFL 339
Query: 305 ARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFC 362
A C GC I LD A WH CF C C G F G C
Sbjct: 340 QLFAPRCQGCQGPI-LDNYISALSAL-WHPD--CFVCRECFAPFSGGSFFEHEGRPLC 393
Score = 79.7 bits (195), Expect = 7e-15
Identities = 49/156 (31%), Positives = 65/156 (41%), Gaps = 5/156 (3%)
Query: 207 LGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAECLRPRCQACDEIIFSPECTEA 266
LG WHP+ F C +C E D + G+ YC R + PRCQ C I A
Sbjct: 302 LGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILD-NYISA 360
Query: 267 EGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQGQMA 326
WH D F C EC A G + + RP C + AR C CG + + ++
Sbjct: 361 LSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCG--LPVTGRCVS 418
Query: 327 YEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFC 362
G+ +H F C+ C R L F R G +C
Sbjct: 419 ALGRRFHPDH--FTCTFCLRPLTKGSFQERAGKPYC 452
Score = 70.1 bits (170), Expect = 6e-12
Identities = 38/114 (33%), Positives = 49/114 (42%), Gaps = 5/114 (4%)
Query: 251 CQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEY 310
C +C++ I T A GR WH +HF C C +LGG + + P C CY R +
Sbjct: 228 CGSCNKPIAGQVVT-ALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR 286
Query: 311 CDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFCSR 364
C C + I + G HWH FCC CG F R G +C R
Sbjct: 287 CGFCNQPIR--HKMVTALGTHWHPEH--FCCVSCGEPFGDEGFHEREGRPYCRR 336
Score = 64.7 bits (156), Expect = 2e-10
Identities = 32/99 (32%), Positives = 42/99 (42%), Gaps = 1/99 (1%)
Query: 205 AGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAECLRPRCQACDEIIFSPECT 264
+ L A WHP CFVC C +F H G+ C H C C + + C
Sbjct: 359 SALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCG-LPVTGRCV 417
Query: 265 EAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACY 303
A GR +H DHF C C L + R +P+C C+
Sbjct: 418 SALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCF 456
>gi|21361591 transforming growth factor beta 1 induced transcript 1
isoform 2 [Homo sapiens]
Length = 444
Score = 95.1 bits (235), Expect = 2e-19
Identities = 58/178 (32%), Positives = 72/178 (40%), Gaps = 11/178 (6%)
Query: 185 ICEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHA 244
+C C K I G + LG WHP+ FVC C L +F G +C +
Sbjct: 210 LCGSCNKPIAGQVVTA------LGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYF 263
Query: 245 ECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYE 304
E PRC C++ I T A G HWH +HFCC C G + + R+ RP+C +
Sbjct: 264 ERFSPRCGFCNQPIRHKMVT-ALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFL 322
Query: 305 ARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFC 362
A C GC I LD A WH CF C C G F G C
Sbjct: 323 QLFAPRCQGCQGPI-LDNYISALSAL-WHPD--CFVCRECFAPFSGGSFFEHEGRPLC 376
Score = 79.7 bits (195), Expect = 7e-15
Identities = 49/156 (31%), Positives = 65/156 (41%), Gaps = 5/156 (3%)
Query: 207 LGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAECLRPRCQACDEIIFSPECTEA 266
LG WHP+ F C +C E D + G+ YC R + PRCQ C I A
Sbjct: 285 LGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILD-NYISA 343
Query: 267 EGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQGQMA 326
WH D F C EC A G + + RP C + AR C CG + + ++
Sbjct: 344 LSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCG--LPVTGRCVS 401
Query: 327 YEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFC 362
G+ +H F C+ C R L F R G +C
Sbjct: 402 ALGRRFHPDH--FTCTFCLRPLTKGSFQERAGKPYC 435
Score = 70.1 bits (170), Expect = 6e-12
Identities = 38/114 (33%), Positives = 49/114 (42%), Gaps = 5/114 (4%)
Query: 251 CQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEY 310
C +C++ I T A GR WH +HF C C +LGG + + P C CY R +
Sbjct: 211 CGSCNKPIAGQVVT-ALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR 269
Query: 311 CDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFCSR 364
C C + I + G HWH FCC CG F R G +C R
Sbjct: 270 CGFCNQPIR--HKMVTALGTHWHPEH--FCCVSCGEPFGDEGFHEREGRPYCRR 319
Score = 64.7 bits (156), Expect = 2e-10
Identities = 32/99 (32%), Positives = 42/99 (42%), Gaps = 1/99 (1%)
Query: 205 AGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAECLRPRCQACDEIIFSPECT 264
+ L A WHP CFVC C +F H G+ C H C C + + C
Sbjct: 342 SALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCG-LPVTGRCV 400
Query: 265 EAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACY 303
A GR +H DHF C C L + R +P+C C+
Sbjct: 401 SALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCF 439
>gi|170932518 paxillin isoform 3 [Homo sapiens]
Length = 424
Score = 92.0 bits (227), Expect = 1e-18
Identities = 52/183 (28%), Positives = 76/183 (41%), Gaps = 11/183 (6%)
Query: 180 TITGAICEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYC 239
T+ +C C K I G + +G WHP+ FVCT CQE + +F G+ YC
Sbjct: 185 TVAKGVCGACKKPIAGQVVTA------MGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYC 238
Query: 240 GRHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHC 299
+ + PRC C+ I T A R WH +HF C +C A G + + + + +C
Sbjct: 239 EKDYHNLFSPRCYYCNGPILDKVVT-ALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYC 297
Query: 300 CACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGL 359
Y A C GC + + ++ WH CF C C + F G
Sbjct: 298 RKDYFDMFAPKCGGCAR--AILENYISALNTLWH--PECFVCRECFTPFVNGSFFEHDGQ 353
Query: 360 IFC 362
+C
Sbjct: 354 PYC 356
Score = 67.8 bits (164), Expect = 3e-11
Identities = 31/99 (31%), Positives = 47/99 (47%), Gaps = 1/99 (1%)
Query: 205 AGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAECLRPRCQACDEIIFSPECT 264
+ L WHP+CFVC C V+ +F H G+ YC H+ E C C + I + C
Sbjct: 322 SALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI-TGRCI 380
Query: 265 EAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACY 303
A + +H +HF C C L + + +P+C C+
Sbjct: 381 TAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCF 419
>gi|170932516 paxillin isoform 2 [Homo sapiens]
Length = 557
Score = 92.0 bits (227), Expect = 1e-18
Identities = 52/183 (28%), Positives = 76/183 (41%), Gaps = 11/183 (6%)
Query: 180 TITGAICEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYC 239
T+ +C C K I G + +G WHP+ FVCT CQE + +F G+ YC
Sbjct: 318 TVAKGVCGACKKPIAGQVVTA------MGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYC 371
Query: 240 GRHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHC 299
+ + PRC C+ I T A R WH +HF C +C A G + + + + +C
Sbjct: 372 EKDYHNLFSPRCYYCNGPILDKVVT-ALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYC 430
Query: 300 CACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGL 359
Y A C GC + + ++ WH CF C C + F G
Sbjct: 431 RKDYFDMFAPKCGGCAR--AILENYISALNTLWH--PECFVCRECFTPFVNGSFFEHDGQ 486
Query: 360 IFC 362
+C
Sbjct: 487 PYC 489
Score = 67.8 bits (164), Expect = 3e-11
Identities = 31/99 (31%), Positives = 47/99 (47%), Gaps = 1/99 (1%)
Query: 205 AGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAECLRPRCQACDEIIFSPECT 264
+ L WHP+CFVC C V+ +F H G+ YC H+ E C C + I + C
Sbjct: 455 SALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI-TGRCI 513
Query: 265 EAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACY 303
A + +H +HF C C L + + +P+C C+
Sbjct: 514 TAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCF 552
>gi|170932514 paxillin isoform 1 [Homo sapiens]
Length = 591
Score = 92.0 bits (227), Expect = 1e-18
Identities = 52/183 (28%), Positives = 76/183 (41%), Gaps = 11/183 (6%)
Query: 180 TITGAICEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYC 239
T+ +C C K I G + +G WHP+ FVCT CQE + +F G+ YC
Sbjct: 352 TVAKGVCGACKKPIAGQVVTA------MGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYC 405
Query: 240 GRHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHC 299
+ + PRC C+ I T A R WH +HF C +C A G + + + + +C
Sbjct: 406 EKDYHNLFSPRCYYCNGPILDKVVT-ALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYC 464
Query: 300 CACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGL 359
Y A C GC + + ++ WH CF C C + F G
Sbjct: 465 RKDYFDMFAPKCGGCAR--AILENYISALNTLWH--PECFVCRECFTPFVNGSFFEHDGQ 520
Query: 360 IFC 362
+C
Sbjct: 521 PYC 523
Score = 67.8 bits (164), Expect = 3e-11
Identities = 31/99 (31%), Positives = 47/99 (47%), Gaps = 1/99 (1%)
Query: 205 AGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAECLRPRCQACDEIIFSPECT 264
+ L WHP+CFVC C V+ +F H G+ YC H+ E C C + I + C
Sbjct: 489 SALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI-TGRCI 547
Query: 265 EAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACY 303
A + +H +HF C C L + + +P+C C+
Sbjct: 548 TAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCF 586
>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
Length = 617
Score = 90.9 bits (224), Expect = 3e-18
Identities = 55/199 (27%), Positives = 79/199 (39%), Gaps = 12/199 (6%)
Query: 169 LGRGIVRI---FPVTITGAICEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELL 225
L RG V+ FP + +C C I G + +G WHP+ F C C+ L
Sbjct: 421 LARGTVQRAERFPASSRTPLCGHCNNVIRGPFLVA------MGRSWHPEEFTCAYCKTSL 474
Query: 226 VDLIYFYHVGKVYCGRHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASL 285
D+ + VYC R + + P C C+ I E A + WH F C C+
Sbjct: 475 ADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMG-EVMHALRQTWHTTCFVCAACKKPF 533
Query: 286 GGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCG 345
G + M P+C Y + C GC + + G WH D CF C+ C
Sbjct: 534 GNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWH--DTCFICAVCH 591
Query: 346 RALLGRPFLPRRGLIFCSR 364
L G+PF ++ C +
Sbjct: 592 VNLEGQPFYSKKDRPLCKK 610
Score = 33.5 bits (75), Expect = 0.59
Identities = 16/57 (28%), Positives = 23/57 (40%), Gaps = 4/57 (7%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRH 242
C C + GD + A LG WH CF+C C L ++ + C +H
Sbjct: 559 CHGCDFPVEAGDKFIEA----LGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKH 611
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 90.9 bits (224), Expect = 3e-18
Identities = 55/199 (27%), Positives = 79/199 (39%), Gaps = 12/199 (6%)
Query: 169 LGRGIVRI---FPVTITGAICEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELL 225
L RG V+ FP + +C C I G + +G WHP+ F C C+ L
Sbjct: 531 LARGTVQRAERFPASSRTPLCGHCNNVIRGPFLVA------MGRSWHPEEFTCAYCKTSL 584
Query: 226 VDLIYFYHVGKVYCGRHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASL 285
D+ + VYC R + + P C C+ I E A + WH F C C+
Sbjct: 585 ADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMG-EVMHALRQTWHTTCFVCAACKKPF 643
Query: 286 GGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCG 345
G + M P+C Y + C GC + + G WH D CF C+ C
Sbjct: 644 GNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWH--DTCFICAVCH 701
Query: 346 RALLGRPFLPRRGLIFCSR 364
L G+PF ++ C +
Sbjct: 702 VNLEGQPFYSKKDRPLCKK 720
Score = 33.5 bits (75), Expect = 0.59
Identities = 16/57 (28%), Positives = 23/57 (40%), Gaps = 4/57 (7%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRH 242
C C + GD + A LG WH CF+C C L ++ + C +H
Sbjct: 669 CHGCDFPVEAGDKFIEA----LGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKH 721
>gi|221316659 leupaxin isoform 1 [Homo sapiens]
Length = 391
Score = 90.5 bits (223), Expect = 4e-18
Identities = 66/255 (25%), Positives = 97/255 (38%), Gaps = 17/255 (6%)
Query: 114 EDKVPYVNSPGEKYRIKQLLHQLPPHDSEAQYCTALEEEEKKELRAFSQQRKRE------ 167
E + P + P K L +L H +E Q A+ + K+ Q K
Sbjct: 79 EAQEPKESPPPSKTSAAAQLDELMAHLTEMQAKVAVRADAGKKHLPDKQDHKASLDSMLG 138
Query: 168 NLGRGIVRIFPVTITGAICEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVD 227
L + + + T+ C C K I G I LG WHP+ FVCT C+E +
Sbjct: 139 GLEQELQDLGIATVPKGHCASCQKPIAGKVIHA------LGQSWHPEHFVCTHCKEEIGS 192
Query: 228 LIYFYHVGKVYCGRHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGG 287
+F G YC + + PRC C I T A + WH +HF C C G
Sbjct: 193 SPFFERSGLAYCPNDYHQLFSPRCAYCAAPILDKVLT-AMNQTWHPEHFFCSHCGEVFGA 251
Query: 288 QRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRA 347
+ + + +P+C + A + C GC + + ++ WH CF C C +
Sbjct: 252 EGFHEKDKKPYCRKDFLAMFSPKCGGCNRPV--LENYLSAMDTVWH--PECFVCGDCFTS 307
Query: 348 LLGRPFLPRRGLIFC 362
F G FC
Sbjct: 308 FSTGSFFELDGRPFC 322
Score = 54.3 bits (129), Expect = 3e-07
Identities = 26/99 (26%), Positives = 42/99 (42%), Gaps = 1/99 (1%)
Query: 205 AGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAECLRPRCQACDEIIFSPECT 264
+ + WHP+CFVC C +F G+ +C H+ C C + I + C
Sbjct: 288 SAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPI-TGRCI 346
Query: 265 EAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACY 303
A G +H +HF C C L + + + +C C+
Sbjct: 347 SAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCF 385
>gi|4758670 leupaxin isoform 2 [Homo sapiens]
Length = 386
Score = 90.5 bits (223), Expect = 4e-18
Identities = 66/255 (25%), Positives = 97/255 (38%), Gaps = 17/255 (6%)
Query: 114 EDKVPYVNSPGEKYRIKQLLHQLPPHDSEAQYCTALEEEEKKELRAFSQQRKRE------ 167
E + P + P K L +L H +E Q A+ + K+ Q K
Sbjct: 74 EAQEPKESPPPSKTSAAAQLDELMAHLTEMQAKVAVRADAGKKHLPDKQDHKASLDSMLG 133
Query: 168 NLGRGIVRIFPVTITGAICEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVD 227
L + + + T+ C C K I G I LG WHP+ FVCT C+E +
Sbjct: 134 GLEQELQDLGIATVPKGHCASCQKPIAGKVIHA------LGQSWHPEHFVCTHCKEEIGS 187
Query: 228 LIYFYHVGKVYCGRHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGG 287
+F G YC + + PRC C I T A + WH +HF C C G
Sbjct: 188 SPFFERSGLAYCPNDYHQLFSPRCAYCAAPILDKVLT-AMNQTWHPEHFFCSHCGEVFGA 246
Query: 288 QRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRA 347
+ + + +P+C + A + C GC + + ++ WH CF C C +
Sbjct: 247 EGFHEKDKKPYCRKDFLAMFSPKCGGCNRPV--LENYLSAMDTVWH--PECFVCGDCFTS 302
Query: 348 LLGRPFLPRRGLIFC 362
F G FC
Sbjct: 303 FSTGSFFELDGRPFC 317
Score = 54.3 bits (129), Expect = 3e-07
Identities = 26/99 (26%), Positives = 42/99 (42%), Gaps = 1/99 (1%)
Query: 205 AGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAECLRPRCQACDEIIFSPECT 264
+ + WHP+CFVC C +F G+ +C H+ C C + I + C
Sbjct: 283 SAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPI-TGRCI 341
Query: 265 EAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACY 303
A G +H +HF C C L + + + +C C+
Sbjct: 342 SAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCF 380
>gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens]
Length = 323
Score = 90.1 bits (222), Expect = 5e-18
Identities = 49/178 (27%), Positives = 75/178 (42%), Gaps = 9/178 (5%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAE 245
C EC K IG V WH CF C C L + + K+ C +
Sbjct: 40 CVECRKPIGADSKEVHYKNR----FWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 95
Query: 246 CLRPRCQACDE-IIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYE 304
P+C+ C + I+ + E +G WH D F C C+ +G + + +C C+E
Sbjct: 96 EDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHE 155
Query: 305 ARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFC 362
+ A++C C + + G + Y+ Q WHA CF C C + L G+ F +C
Sbjct: 156 TKFAKHCVKCNK--AITSGGITYQDQPWHAD--CFVCVTCSKKLAGQRFTAVEDQYYC 209
Score = 74.3 bits (181), Expect = 3e-13
Identities = 40/129 (31%), Positives = 57/129 (44%), Gaps = 5/129 (3%)
Query: 186 CEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAE 245
C+ C K I GD V G WH CF C+ C++++ +F YC H
Sbjct: 101 CKGCFKAIVAGDQNVEYK----GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHET 156
Query: 246 CLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEA 305
C C++ I S T + + WH D F C C L GQR+ + + +C CY+
Sbjct: 157 KFAKHCVKCNKAITSGGITYQD-QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
Query: 306 RHAEYCDGC 314
A+ C GC
Sbjct: 216 FVAKKCAGC 224
Score = 62.8 bits (151), Expect = 9e-10
Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 2/103 (1%)
Query: 274 DHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWH 333
+ F C C L G++YV + C C++ A C C + IG D ++ Y+ + WH
Sbjct: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
Query: 334 ASDRCFCCSRCGRALLGRPFLPRRGLIFCSRACSLGSEPTAPG 376
D CF C++C L F+ + I C++ + P G
Sbjct: 63 --DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKG 103
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.452
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,239,703
Number of Sequences: 37866
Number of extensions: 1941570
Number of successful extensions: 19060
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 274
Number of HSP's successfully gapped in prelim test: 967
Number of HSP's that attempted gapping in prelim test: 12696
Number of HSP's gapped (non-prelim): 4980
length of query: 615
length of database: 18,247,518
effective HSP length: 108
effective length of query: 507
effective length of database: 14,157,990
effective search space: 7178100930
effective search space used: 7178100930
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.