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Search of human proteins with 7706753
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7706753 ubiquitin carboxyl-terminal hydrolase L5 [Homo
sapiens]
(329 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7706753 ubiquitin carboxyl-terminal hydrolase L5 [Homo sapiens] 657 0.0
gi|4757836 BRCA1 associated protein-1 [Homo sapiens] 185 5e-47
gi|5174741 ubiquitin carboxyl-terminal esterase L3 [Homo sapiens] 85 8e-17
gi|21361091 ubiquitin carboxyl-terminal esterase L1 [Homo sapiens] 69 7e-12
gi|55741447 pleckstrin homology domain containing, family H (wit... 37 0.032
gi|57768564 hypothetical protein LOC23281 isoform b [Homo sapiens] 36 0.041
gi|140161498 hypothetical protein LOC23281 isoform a [Homo sapiens] 36 0.041
gi|221219026 pleckstrin homology-like domain, family B, member 1... 36 0.054
gi|221219024 pleckstrin homology-like domain, family B, member 1... 36 0.054
gi|38424073 pleckstrin homology-like domain, family B, member 1 ... 36 0.054
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 35 0.070
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 35 0.070
gi|32483374 nucleolar protein 5A [Homo sapiens] 35 0.092
gi|219555661 intraflagellar transport 81-like isoform 1 [Homo sa... 35 0.092
gi|32526901 intraflagellar transport 81-like isoform 1 [Homo sap... 35 0.092
gi|189217904 RPGRIP1-like isoform b [Homo sapiens] 34 0.16
gi|118442834 RPGRIP1-like isoform a [Homo sapiens] 34 0.16
gi|100814339 coiled-coil domain containing 146 [Homo sapiens] 34 0.16
gi|56961680 coiled-coil domain containing 147 [Homo sapiens] 34 0.16
gi|148277620 type I hair keratin KA35 [Homo sapiens] 34 0.20
gi|148746195 trichohyalin [Homo sapiens] 34 0.20
gi|223005859 WD repeat domain 67 isoform 1 [Homo sapiens] 33 0.27
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 33 0.27
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 33 0.27
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 33 0.27
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 33 0.27
gi|31542634 filamin A interacting protein 1 [Homo sapiens] 33 0.27
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 33 0.27
gi|116488398 keratin 32 [Homo sapiens] 33 0.35
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 32 0.60
>gi|7706753 ubiquitin carboxyl-terminal hydrolase L5 [Homo sapiens]
Length = 329
Score = 657 bits (1695), Expect = 0.0
Identities = 329/329 (100%), Positives = 329/329 (100%)
Query: 1 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQP 60
MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQP
Sbjct: 1 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQP 60
Query: 61 GEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQS 120
GEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQS
Sbjct: 61 GEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQS 120
Query: 121 FDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRLYELDG 180
FDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRLYELDG
Sbjct: 121 FDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRLYELDG 180
Query: 181 LREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQR 240
LREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQR
Sbjct: 181 LREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQR 240
Query: 241 QLAEEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELL 300
QLAEEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELL
Sbjct: 241 QLAEEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELL 300
Query: 301 KTLAEHQQLIPLVEKAKEKQNAKKAQETK 329
KTLAEHQQLIPLVEKAKEKQNAKKAQETK
Sbjct: 301 KTLAEHQQLIPLVEKAKEKQNAKKAQETK 329
>gi|4757836 BRCA1 associated protein-1 [Homo sapiens]
Length = 729
Score = 185 bits (469), Expect = 5e-47
Identities = 108/250 (43%), Positives = 151/250 (60%), Gaps = 23/250 (9%)
Query: 8 WCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPAG- 66
W +ESDPG+FT L++ FG +G QVEEI+ L+ + PV+G IFLFKW
Sbjct: 5 WLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKC---QGPVYGFIFLFKWIEERRSRRK 61
Query: 67 --------SVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFS 118
SV+ D ++ +FFA Q+I N+CAT A++SVLLNC+ D LG TLS K+F+
Sbjct: 62 VSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSSVD--LGPTLSRMKDFT 119
Query: 119 QSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTK----TSAKEEDAFHFVSYVPVNGR 174
+ F KG A+ N+ + + HNS AR + K ++ + +AFHFVSYVP+ GR
Sbjct: 120 KGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGR 179
Query: 175 LYELDGLREGPIDLGACNQD-DWISAVRPVIEKRIQKYSEGE----IRFNLMAIVSDRKM 229
L+ELDGL+ PID G +D +W R VI +RI + GE IRFNLMA+V DR++
Sbjct: 180 LFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRI 239
Query: 230 IYEQKIAELQ 239
YE ++ L+
Sbjct: 240 KYEARLHVLK 249
Score = 51.2 bits (121), Expect = 1e-06
Identities = 23/61 (37%), Positives = 40/61 (65%)
Query: 255 SMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVE 314
++L +++E+A + ++EEV+K K++KI++ RR HNY FI + LA+ L LVE
Sbjct: 634 ALLKCVEAEIANYEACLKEEVEKRKKFKIDDQRRTHNYDEFICTFISMLAQEGMLANLVE 693
Query: 315 K 315
+
Sbjct: 694 Q 694
>gi|5174741 ubiquitin carboxyl-terminal esterase L3 [Homo sapiens]
Length = 230
Score = 85.1 bits (209), Expect = 8e-17
Identities = 67/228 (29%), Positives = 111/228 (48%), Gaps = 18/228 (7%)
Query: 8 WCLMESDPGVFTELIKGFGCR-GAQVEEIWSLEPENFEKL-KPVHGLIFLF----KWQ-- 59
W +E++P V + +K G Q +++ ++PE + +PV ++ LF K++
Sbjct: 6 WLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVF 65
Query: 60 --PGEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHL--GETLSEFK 115
EE S QD +++F KQ I+NAC T ++ + N +H G TL +F
Sbjct: 66 RTEEEEKIKSQGQDVT-SSVYFMKQTISNACGTIGLIHAIAN-NKDKMHFESGSTLKKFL 123
Query: 116 EFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRL 175
E S S + L N D IR H + A + E S E+ HF++ V V+G L
Sbjct: 124 EESVSMSPEERARYLENYDAIRVTHETSAHEGQTE---APSIDEKVDLHFIALVHVDGHL 180
Query: 176 YELDGLREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAI 223
YELDG + PI+ G + + + V +K +++ E+RFN +A+
Sbjct: 181 YELDGRKPFPINHGETSDETLLEDAIEVCKKFMER-DPDELRFNAIAL 227
>gi|21361091 ubiquitin carboxyl-terminal esterase L1 [Homo sapiens]
Length = 223
Score = 68.6 bits (166), Expect = 7e-12
Identities = 55/227 (24%), Positives = 103/227 (45%), Gaps = 27/227 (11%)
Query: 11 MESDPGVFTELIKGFGCRGA-QVEEIWSLEPENFEKLK-PVHGLIFLF---------KWQ 59
ME +P + +++ G G + ++ LE E+ + P L+ LF + +
Sbjct: 6 MEINPEMLNKVLSRLGVAGQWRFVDVLGLEEESLGSVPAPACALLLLFPLTAQHENFRKK 65
Query: 60 PGEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQD---VHLGETLSEFKE 116
EE G V ++F KQ I N+C T ++ + N +QD G L +F
Sbjct: 66 QIEELKGQEVSPK----VYFMKQTIGNSCGTIGLIHAVAN--NQDKLGFEDGSVLKQFLS 119
Query: 117 FSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRLY 176
++ + ++ I+ H++ A++ D K + FHF+ + V+G LY
Sbjct: 120 ETEKMSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVN------FHFILFNNVDGHLY 173
Query: 177 ELDGLREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAI 223
ELDG P++ GA ++D + V + ++ +GE+RF+ +A+
Sbjct: 174 ELDGRMPFPVNHGASSEDTLLKDAAKVCREFTER-EQGEVRFSAVAL 219
>gi|55741447 pleckstrin homology domain containing, family H (with
MyTH4 domain) member 1 [Homo sapiens]
Length = 1364
Score = 36.6 bits (83), Expect = 0.032
Identities = 34/125 (27%), Positives = 57/125 (45%), Gaps = 17/125 (13%)
Query: 205 EKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQLAEEEPMDTDQGNSMLSAIQSEV 264
+KR RF L A S + + K+ EL+++L E E ++E
Sbjct: 15 QKRCLTLETQLFRFRLQA--SKIRELLADKMQELEQRLLEAEQ-------------RAEN 59
Query: 265 AKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKAKEKQNAKK 324
A+ Q+ + EE K+K ++N+ + + ELLK + +LI +E EKQ +
Sbjct: 60 AETQVGVMEE--KVKLSNLKNVDSEGSLHRKYQELLKAIKGKDELISQLEAQLEKQKQMR 117
Query: 325 AQETK 329
A+E K
Sbjct: 118 AEEAK 122
>gi|57768564 hypothetical protein LOC23281 isoform b [Homo sapiens]
Length = 348
Score = 36.2 bits (82), Expect = 0.041
Identities = 24/89 (26%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
Query: 197 ISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQLAEEEPMDTDQGNSM 256
+ +++ V+E + Q+ E E + + ++++ +I E+KI LQ+Q E+ DQ +
Sbjct: 218 MKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQ-NEDLKARIDQNTVV 276
Query: 257 LSAIQSEVAKNQMLIEEEVQKLKRYKIEN 285
+ E A Q +E+E Q+ KR N
Sbjct: 277 TRQLSEENANLQEYVEKETQEKKRLSRTN 305
>gi|140161498 hypothetical protein LOC23281 isoform a [Homo sapiens]
Length = 1379
Score = 36.2 bits (82), Expect = 0.041
Identities = 24/89 (26%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
Query: 197 ISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQLAEEEPMDTDQGNSM 256
+ +++ V+E + Q+ E E + + ++++ +I E+KI LQ+Q E+ DQ +
Sbjct: 1249 MKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQ-NEDLKARIDQNTVV 1307
Query: 257 LSAIQSEVAKNQMLIEEEVQKLKRYKIEN 285
+ E A Q +E+E Q+ KR N
Sbjct: 1308 TRQLSEENANLQEYVEKETQEKKRLSRTN 1336
>gi|221219026 pleckstrin homology-like domain, family B, member 1
isoform b [Homo sapiens]
Length = 1319
Score = 35.8 bits (81), Expect = 0.054
Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 4/73 (5%)
Query: 226 DRKMIYEQKIAELQRQLAEEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKRYKIEN 285
+R M ++ EL+RQ EEE +Q L QSE A+ Q L+E+EV K++ +
Sbjct: 1116 NRLMESREREMELRRQALEEERRRREQVERRL---QSESARRQQLVEKEV-KMREKQFSQ 1171
Query: 286 IRRKHNYLPFIME 298
R YLP E
Sbjct: 1172 ARPLTRYLPIRKE 1184
>gi|221219024 pleckstrin homology-like domain, family B, member 1
isoform a [Homo sapiens]
Length = 1377
Score = 35.8 bits (81), Expect = 0.054
Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 4/73 (5%)
Query: 226 DRKMIYEQKIAELQRQLAEEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKRYKIEN 285
+R M ++ EL+RQ EEE +Q L QSE A+ Q L+E+EV K++ +
Sbjct: 1163 NRLMESREREMELRRQALEEERRRREQVERRL---QSESARRQQLVEKEV-KMREKQFSQ 1218
Query: 286 IRRKHNYLPFIME 298
R YLP E
Sbjct: 1219 ARPLTRYLPIRKE 1231
>gi|38424073 pleckstrin homology-like domain, family B, member 1
isoform a [Homo sapiens]
Length = 1377
Score = 35.8 bits (81), Expect = 0.054
Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 4/73 (5%)
Query: 226 DRKMIYEQKIAELQRQLAEEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKRYKIEN 285
+R M ++ EL+RQ EEE +Q L QSE A+ Q L+E+EV K++ +
Sbjct: 1163 NRLMESREREMELRRQALEEERRRREQVERRL---QSESARRQQLVEKEV-KMREKQFSQ 1218
Query: 286 IRRKHNYLPFIME 298
R YLP E
Sbjct: 1219 ARPLTRYLPIRKE 1231
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 35.4 bits (80), Expect = 0.070
Identities = 31/127 (24%), Positives = 60/127 (47%), Gaps = 15/127 (11%)
Query: 205 EKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQL--AEEEPMDTDQGNSMLSAIQS 262
E+R++K + R M ++K EQK A++ + A+EE + ++ +A +
Sbjct: 575 EERLRKVLQARERVEQMK--EEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKM 632
Query: 263 EVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKAKEKQNA 322
E + + EEE ++L+ + E R+H ELL+ E +Q E+ ++ A
Sbjct: 633 EEVEARRKQEEEARRLRWLQQEEEERRH------QELLQKKKEEEQ-----ERLRKAAEA 681
Query: 323 KKAQETK 329
K+ E +
Sbjct: 682 KRLAEQR 688
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 35.4 bits (80), Expect = 0.070
Identities = 31/127 (24%), Positives = 60/127 (47%), Gaps = 15/127 (11%)
Query: 205 EKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQL--AEEEPMDTDQGNSMLSAIQS 262
E+R++K + R M ++K EQK A++ + A+EE + ++ +A +
Sbjct: 571 EERLRKVLQARERVEQMK--EEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKM 628
Query: 263 EVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKAKEKQNA 322
E + + EEE ++L+ + E R+H ELL+ E +Q E+ ++ A
Sbjct: 629 EEVEARRKQEEEARRLRWLQQEEEERRH------QELLQKKKEEEQ-----ERLRKAAEA 677
Query: 323 KKAQETK 329
K+ E +
Sbjct: 678 KRLAEQR 684
>gi|32483374 nucleolar protein 5A [Homo sapiens]
Length = 594
Score = 35.0 bits (79), Expect = 0.092
Identities = 20/95 (21%), Positives = 46/95 (48%)
Query: 200 VRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQLAEEEPMDTDQGNSMLSA 259
+R +E+R+ Y GEI + ++ + + E+ AE+ R+L ++E + L+A
Sbjct: 397 LREQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAA 456
Query: 260 IQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLP 294
+ ++N EE +++ + ++K +P
Sbjct: 457 LALASSENSSSTPEECEEMSEKPKKKKKQKPQEVP 491
>gi|219555661 intraflagellar transport 81-like isoform 1 [Homo
sapiens]
Length = 676
Score = 35.0 bits (79), Expect = 0.092
Identities = 28/114 (24%), Positives = 55/114 (48%), Gaps = 4/114 (3%)
Query: 220 LMAIVSDRKMIYEQKIAELQ--RQLAEEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQK 277
L ++VS++K I EL+ RQ +E + D+ S + + + N+ +E+EV++
Sbjct: 493 LYSLVSEKKSALASVIKELRQLRQKYQELTQECDEKKSQYDSCAAGLESNRSKLEQEVRR 552
Query: 278 LKRYKIENIRRKH--NYLPFIMELLKTLAEHQQLIPLVEKAKEKQNAKKAQETK 329
L+ ++ R H N + +E+ A + + +EK+ A + Q TK
Sbjct: 553 LREECLQEESRYHYTNCMIKNLEVQLRRATDEMKAYISSDQQEKRKAIREQYTK 606
>gi|32526901 intraflagellar transport 81-like isoform 1 [Homo
sapiens]
Length = 676
Score = 35.0 bits (79), Expect = 0.092
Identities = 28/114 (24%), Positives = 55/114 (48%), Gaps = 4/114 (3%)
Query: 220 LMAIVSDRKMIYEQKIAELQ--RQLAEEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQK 277
L ++VS++K I EL+ RQ +E + D+ S + + + N+ +E+EV++
Sbjct: 493 LYSLVSEKKSALASVIKELRQLRQKYQELTQECDEKKSQYDSCAAGLESNRSKLEQEVRR 552
Query: 278 LKRYKIENIRRKH--NYLPFIMELLKTLAEHQQLIPLVEKAKEKQNAKKAQETK 329
L+ ++ R H N + +E+ A + + +EK+ A + Q TK
Sbjct: 553 LREECLQEESRYHYTNCMIKNLEVQLRRATDEMKAYISSDQQEKRKAIREQYTK 606
>gi|189217904 RPGRIP1-like isoform b [Homo sapiens]
Length = 1235
Score = 34.3 bits (77), Expect = 0.16
Identities = 26/98 (26%), Positives = 45/98 (45%), Gaps = 15/98 (15%)
Query: 247 PMDTDQGNSMLSAIQSEVAKNQMLIE------EEVQKLKRYKIENIRRKHNYLPFIMELL 300
PM T GNS+L + E+ + +I+ EE++ L +RRK N + + L
Sbjct: 191 PMFTKYGNSLLEEARGEIRNLENVIQSQRGQIEELEHLAEILKTQLRRKENEIELSLLQL 250
Query: 301 K---------TLAEHQQLIPLVEKAKEKQNAKKAQETK 329
+ + ++ ++I L ++ EK NA A E K
Sbjct: 251 REQQATDQRSNIRDNVEMIKLHKQLVEKSNALSAMEGK 288
>gi|118442834 RPGRIP1-like isoform a [Homo sapiens]
Length = 1315
Score = 34.3 bits (77), Expect = 0.16
Identities = 26/98 (26%), Positives = 45/98 (45%), Gaps = 15/98 (15%)
Query: 247 PMDTDQGNSMLSAIQSEVAKNQMLIE------EEVQKLKRYKIENIRRKHNYLPFIMELL 300
PM T GNS+L + E+ + +I+ EE++ L +RRK N + + L
Sbjct: 191 PMFTKYGNSLLEEARGEIRNLENVIQSQRGQIEELEHLAEILKTQLRRKENEIELSLLQL 250
Query: 301 K---------TLAEHQQLIPLVEKAKEKQNAKKAQETK 329
+ + ++ ++I L ++ EK NA A E K
Sbjct: 251 REQQATDQRSNIRDNVEMIKLHKQLVEKSNALSAMEGK 288
>gi|100814339 coiled-coil domain containing 146 [Homo sapiens]
Length = 955
Score = 34.3 bits (77), Expect = 0.16
Identities = 43/212 (20%), Positives = 97/212 (45%), Gaps = 49/212 (23%)
Query: 145 RQQMFEFDTKTSAKEEDAFHFVSYVPVNGRLYELDGLREGPIDLGACNQDDWISAVRPVI 204
R+Q+ ++ + +A +E FH Y L+ L+E I + + + I+ +
Sbjct: 124 REQLLKYQNEYNAVKEREFH---------NQYRLNSLKEEKIII--VKEFEKITKPGEME 172
Query: 205 EK-RIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQLAEEEPMDTDQGNSMLSAIQSE 263
+K +I + S E+R +M + K + E ++ ++ L E++ ++ G+ ++ ++ E
Sbjct: 173 KKMKILRESTEELRKEIMQKKLEIKNLREDLASKQKQLLKEQKELEELLGHQVV--LKDE 230
Query: 264 VAKNQML---IEEEVQKLKRYKIE-----------------NIRRKHNYLPFIMELLKTL 303
VA +Q + I +E++K+ R K+E ++++ N + I++ + +
Sbjct: 231 VAHHQTIPVQIGKEIEKITRKKVEMEKKKIVLEQEVKTLNDSLKKVENKVSAIVDEKENV 290
Query: 304 A---------------EHQQLIPLVEKAKEKQ 320
EH QL+ L+E A+E +
Sbjct: 291 IKEVEGKRALLEIKEREHNQLVKLLELARENE 322
>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
Length = 872
Score = 34.3 bits (77), Expect = 0.16
Identities = 28/97 (28%), Positives = 50/97 (51%), Gaps = 2/97 (2%)
Query: 233 QKIAELQRQLAEEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNY 292
+K +L+++L + + D D + + A+Q V K++ +++ Q+LK KI N R
Sbjct: 216 RKKEKLEKELKQIQA-DMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKEL 274
Query: 293 LPFIMELLKTLAEHQQLIPLVEKAKEKQNAKKAQETK 329
F M K E++Q LV + ++N +KA E K
Sbjct: 275 EQFQMRNAKLQQENEQ-HSLVCEQLSQENQQKALELK 310
>gi|148277620 type I hair keratin KA35 [Homo sapiens]
Length = 491
Score = 33.9 bits (76), Expect = 0.20
Identities = 22/67 (32%), Positives = 33/67 (49%)
Query: 221 MAIVSDRKMIYEQKIAELQRQLAEEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKR 280
M I+++R Y QK+ L+R+ AE E ++ N L + + IEE QK+
Sbjct: 100 MQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCPDYLSYYTTIEELQQKILC 159
Query: 281 YKIENIR 287
K EN R
Sbjct: 160 TKAENSR 166
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 33.9 bits (76), Expect = 0.20
Identities = 25/104 (24%), Positives = 50/104 (48%), Gaps = 2/104 (1%)
Query: 226 DRKMIYEQKIAELQRQLAEEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKRYKIEN 285
+R+ EQ+ + R EEE A+Q ++ K Q L++EE ++L+R + E
Sbjct: 861 ERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREK 920
Query: 286 IRRKHNYLPFIMELLKTLAEHQQLIPLVEKAKEKQNAKKAQETK 329
RR+ + E + L + ++ + E+ K ++ ++ Q K
Sbjct: 921 RRRQEQERQYREE--EQLQQEEEQLLREEREKRRRQERERQYRK 962
>gi|223005859 WD repeat domain 67 isoform 1 [Homo sapiens]
Length = 1066
Score = 33.5 bits (75), Expect = 0.27
Identities = 29/131 (22%), Positives = 59/131 (45%), Gaps = 29/131 (22%)
Query: 224 VSDRKMIYEQKIAELQRQLAEEEPMDTD-----------QGNSMLSAIQSEVAKNQMLIE 272
+ +K +YE+ + E Q LA+E D D + ++ A +++ K Q +I+
Sbjct: 824 LESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIK 883
Query: 273 E--------------EVQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKAKE 318
E ++Q L + K ++++R Y E+ K L E+++ + A
Sbjct: 884 ENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCY----QEVAKLLRENRRKEIEIINAMV 939
Query: 319 KQNAKKAQETK 329
++ AKK +E +
Sbjct: 940 EEEAKKWKEAE 950
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 33.5 bits (75), Expect = 0.27
Identities = 37/154 (24%), Positives = 72/154 (46%), Gaps = 25/154 (16%)
Query: 192 NQDDWISAVRPVIEKRIQKYS-----EGEIRFNLMAIVSDRKMIYEQKIAELQRQLAEEE 246
+Q++ +S R ++E+RI + E E NL + K +E I+EL+ +L +EE
Sbjct: 992 DQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKL----KNKHESMISELEVRLKKEE 1047
Query: 247 PM-------------DTDQGNSMLSAIQSEVAKNQMLI---EEEVQKLKRYKIENIRRKH 290
D + ++ +Q+++A+ +M + EEE+Q + I +K+
Sbjct: 1048 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1107
Query: 291 NYLPFIMELLKTLAEHQQLIPLVEKAKEKQNAKK 324
N L I EL +++ Q+ + A+ K +K
Sbjct: 1108 NALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1141
Score = 30.4 bits (67), Expect = 2.3
Identities = 47/231 (20%), Positives = 95/231 (41%), Gaps = 27/231 (11%)
Query: 113 EFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTS-AKEEDAFHFVSYVPV 171
+ K+ D+A+KG + I+Q+ A+ + F+ + + + A ++ F
Sbjct: 1625 DLKDLELQADSAIKG----REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK 1680
Query: 172 NGRLYELDGLREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMA---IVSDRK 228
+ E D ++ Q+D +A R + ++K E + ++ + D K
Sbjct: 1681 KAKSLEADLMQL---------QEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEK 1731
Query: 229 MIYEQKIAELQRQLAEEE-PMDTDQGNSMLSAIQSEVAKNQMLIEEEV--------QKLK 279
E +IA+L+ +L EE+ M+ + Q+E N++ E Q+L+
Sbjct: 1732 RRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLE 1791
Query: 280 RYKIENIRRKHNYLPFIMELLK-TLAEHQQLIPLVEKAKEKQNAKKAQETK 329
R E + H + K T+A + I +E+ E++ +K TK
Sbjct: 1792 RQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATK 1842
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 33.5 bits (75), Expect = 0.27
Identities = 37/154 (24%), Positives = 72/154 (46%), Gaps = 25/154 (16%)
Query: 192 NQDDWISAVRPVIEKRIQKYS-----EGEIRFNLMAIVSDRKMIYEQKIAELQRQLAEEE 246
+Q++ +S R ++E+RI + E E NL + K +E I+EL+ +L +EE
Sbjct: 999 DQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKL----KNKHESMISELEVRLKKEE 1054
Query: 247 PM-------------DTDQGNSMLSAIQSEVAKNQMLI---EEEVQKLKRYKIENIRRKH 290
D + ++ +Q+++A+ +M + EEE+Q + I +K+
Sbjct: 1055 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1114
Query: 291 NYLPFIMELLKTLAEHQQLIPLVEKAKEKQNAKK 324
N L I EL +++ Q+ + A+ K +K
Sbjct: 1115 NALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1148
Score = 30.4 bits (67), Expect = 2.3
Identities = 47/231 (20%), Positives = 95/231 (41%), Gaps = 27/231 (11%)
Query: 113 EFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTS-AKEEDAFHFVSYVPV 171
+ K+ D+A+KG + I+Q+ A+ + F+ + + + A ++ F
Sbjct: 1632 DLKDLELQADSAIKG----REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK 1687
Query: 172 NGRLYELDGLREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMA---IVSDRK 228
+ E D ++ Q+D +A R + ++K E + ++ + D K
Sbjct: 1688 KAKSLEADLMQL---------QEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEK 1738
Query: 229 MIYEQKIAELQRQLAEEE-PMDTDQGNSMLSAIQSEVAKNQMLIEEEV--------QKLK 279
E +IA+L+ +L EE+ M+ + Q+E N++ E Q+L+
Sbjct: 1739 RRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLE 1798
Query: 280 RYKIENIRRKHNYLPFIMELLK-TLAEHQQLIPLVEKAKEKQNAKKAQETK 329
R E + H + K T+A + I +E+ E++ +K TK
Sbjct: 1799 RQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATK 1849
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 33.5 bits (75), Expect = 0.27
Identities = 37/154 (24%), Positives = 72/154 (46%), Gaps = 25/154 (16%)
Query: 192 NQDDWISAVRPVIEKRIQKYS-----EGEIRFNLMAIVSDRKMIYEQKIAELQRQLAEEE 246
+Q++ +S R ++E+RI + E E NL + K +E I+EL+ +L +EE
Sbjct: 999 DQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKL----KNKHESMISELEVRLKKEE 1054
Query: 247 PM-------------DTDQGNSMLSAIQSEVAKNQMLI---EEEVQKLKRYKIENIRRKH 290
D + ++ +Q+++A+ +M + EEE+Q + I +K+
Sbjct: 1055 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1114
Query: 291 NYLPFIMELLKTLAEHQQLIPLVEKAKEKQNAKK 324
N L I EL +++ Q+ + A+ K +K
Sbjct: 1115 NALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1148
Score = 30.4 bits (67), Expect = 2.3
Identities = 47/231 (20%), Positives = 95/231 (41%), Gaps = 27/231 (11%)
Query: 113 EFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTS-AKEEDAFHFVSYVPV 171
+ K+ D+A+KG + I+Q+ A+ + F+ + + + A ++ F
Sbjct: 1632 DLKDLELQADSAIKG----REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK 1687
Query: 172 NGRLYELDGLREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMA---IVSDRK 228
+ E D ++ Q+D +A R + ++K E + ++ + D K
Sbjct: 1688 KAKSLEADLMQL---------QEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEK 1738
Query: 229 MIYEQKIAELQRQLAEEE-PMDTDQGNSMLSAIQSEVAKNQMLIEEEV--------QKLK 279
E +IA+L+ +L EE+ M+ + Q+E N++ E Q+L+
Sbjct: 1739 RRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLE 1798
Query: 280 RYKIENIRRKHNYLPFIMELLK-TLAEHQQLIPLVEKAKEKQNAKKAQETK 329
R E + H + K T+A + I +E+ E++ +K TK
Sbjct: 1799 RQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATK 1849
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 33.5 bits (75), Expect = 0.27
Identities = 37/154 (24%), Positives = 72/154 (46%), Gaps = 25/154 (16%)
Query: 192 NQDDWISAVRPVIEKRIQKYS-----EGEIRFNLMAIVSDRKMIYEQKIAELQRQLAEEE 246
+Q++ +S R ++E+RI + E E NL + K +E I+EL+ +L +EE
Sbjct: 992 DQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKL----KNKHESMISELEVRLKKEE 1047
Query: 247 PM-------------DTDQGNSMLSAIQSEVAKNQMLI---EEEVQKLKRYKIENIRRKH 290
D + ++ +Q+++A+ +M + EEE+Q + I +K+
Sbjct: 1048 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1107
Query: 291 NYLPFIMELLKTLAEHQQLIPLVEKAKEKQNAKK 324
N L I EL +++ Q+ + A+ K +K
Sbjct: 1108 NALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1141
Score = 30.4 bits (67), Expect = 2.3
Identities = 47/231 (20%), Positives = 95/231 (41%), Gaps = 27/231 (11%)
Query: 113 EFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTS-AKEEDAFHFVSYVPV 171
+ K+ D+A+KG + I+Q+ A+ + F+ + + + A ++ F
Sbjct: 1625 DLKDLELQADSAIKG----REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK 1680
Query: 172 NGRLYELDGLREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMA---IVSDRK 228
+ E D ++ Q+D +A R + ++K E + ++ + D K
Sbjct: 1681 KAKSLEADLMQL---------QEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEK 1731
Query: 229 MIYEQKIAELQRQLAEEE-PMDTDQGNSMLSAIQSEVAKNQMLIEEEV--------QKLK 279
E +IA+L+ +L EE+ M+ + Q+E N++ E Q+L+
Sbjct: 1732 RRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLE 1791
Query: 280 RYKIENIRRKHNYLPFIMELLK-TLAEHQQLIPLVEKAKEKQNAKKAQETK 329
R E + H + K T+A + I +E+ E++ +K TK
Sbjct: 1792 RQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATK 1842
>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
Length = 1213
Score = 33.5 bits (75), Expect = 0.27
Identities = 32/111 (28%), Positives = 52/111 (46%), Gaps = 27/111 (24%)
Query: 230 IYEQKIAELQRQLAEEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRK 289
+YE+ I+EL R EE+ +T + ML Q+L+ E+ + Y++EN + K
Sbjct: 143 VYEKPISELDR--LEEKQKETYR--RMLE---------QLLLAEKCHRRTVYELENEKHK 189
Query: 290 H-----------NYLPFIMELLKTLAEHQQLIPLVEKAKEKQNAKKAQETK 329
H N L E LK L E ++ + KEK+NAK+ + +
Sbjct: 190 HTDYMNKSDDFTNLLEQERERLKKLLEQEK---AYQARKEKENAKRLNKLR 237
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 33.5 bits (75), Expect = 0.27
Identities = 36/189 (19%), Positives = 83/189 (43%), Gaps = 39/189 (20%)
Query: 140 HNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRLYELDGLREGPIDLGACNQDDWISA 199
+N QQ+F+ ++K ++ E + H D LRE + L +D +S
Sbjct: 1058 NNEILSQQLFKTESKLNSLEIEFHH------------TRDALREKTLGLERVQKD--LSQ 1103
Query: 200 VRPVIEKRIQKYSEGEIRFNL-----------MAIVSDRKMIYEQKIAELQRQLAEEEPM 248
+ +++ QKY +++ N ++ + M+ Q++ + + +E
Sbjct: 1104 TQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKT 1163
Query: 249 DT---DQGNSMLSAIQSEVAKNQMLIEEEVQKL---------KRYKIENIRRKHNYLPFI 296
DQ ++++ +Q+E K +L+EE ++L ++Y+ EN + + + +
Sbjct: 1164 VINIQDQFHAIVQKLQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREVV--V 1221
Query: 297 MELLKTLAE 305
+L + LA+
Sbjct: 1222 RQLQQELAD 1230
Score = 30.0 bits (66), Expect = 3.0
Identities = 31/109 (28%), Positives = 52/109 (47%), Gaps = 20/109 (18%)
Query: 224 VSDRKMIYEQKIAELQ---RQLAEEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKR 280
+ +R+ YE + AE + RQL ++E DT + SM A ++ ++ +E+E Q LK+
Sbjct: 1203 LKERQYQYENEKAEREVVVRQL-QQELADTLKKQSMSEASLEVTSRYRINLEDETQDLKK 1261
Query: 281 YKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKAK------EKQNAK 323
K+ IR +L + H + + EK + EK NAK
Sbjct: 1262 -KLGQIRN---------QLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAK 1300
>gi|116488398 keratin 32 [Homo sapiens]
Length = 448
Score = 33.1 bits (74), Expect = 0.35
Identities = 23/80 (28%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Query: 211 YSEGEIRFN---LMAIVSDRKMIYEQKIAELQRQLAEEEPMDTDQGNSMLSAIQSEVAKN 267
YSEG N M ++DR Y ++ +L+++ AE E + +S + + + +
Sbjct: 87 YSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRIQEASHSQVLTMTPDYQSH 146
Query: 268 QMLIEEEVQKLKRYKIENIR 287
IEE QK+ K EN R
Sbjct: 147 FRTIEELQQKILCTKAENAR 166
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 32.3 bits (72), Expect = 0.60
Identities = 26/109 (23%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 217 RFNLMAIVSDRKMIYEQKIAELQRQLAEEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQ 276
R N +A D+K K+ + EE + + ++ +E+ K + EE +
Sbjct: 1435 RANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALD 1494
Query: 277 KLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKAKEKQNAKKA 325
+L+ K EN N I +L + +AE+ + I +EK++++ +KA
Sbjct: 1495 QLETVKREN----KNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKA 1539
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,376,627
Number of Sequences: 37866
Number of extensions: 472893
Number of successful extensions: 2576
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 99
Number of HSP's that attempted gapping in prelim test: 2420
Number of HSP's gapped (non-prelim): 272
length of query: 329
length of database: 18,247,518
effective HSP length: 103
effective length of query: 226
effective length of database: 14,347,320
effective search space: 3242494320
effective search space used: 3242494320
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.