Guide to the Human Genome
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Search of human proteins with 7706501

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7706501 WW domain binding protein 11 [Homo sapiens]
         (641 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7706501 WW domain binding protein 11 [Homo sapiens]               1325   0.0  
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...   120   3e-27
gi|160707881 formin 2 [Homo sapiens]                                  115   1e-25
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]    109   7e-24
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...   108   1e-23
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]               106   8e-23
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...   105   1e-22
gi|210032580 SET domain containing 1B [Homo sapiens]                  103   5e-22
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                    103   6e-22
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                    103   6e-22
gi|146134388 YLP motif containing 1 [Homo sapiens]                    102   1e-21
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...   101   2e-21
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]              100   4e-21
gi|163965366 nascent polypeptide-associated complex alpha subuni...    99   2e-20
gi|73808090 zinc finger protein 207 isoform b [Homo sapiens]           98   3e-20
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    97   6e-20
gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho...    97   6e-20
gi|153792074 proline rich 12 [Homo sapiens]                            97   6e-20
gi|72004269 tetra-peptide repeat homeobox [Homo sapiens]               96   1e-19
gi|18959210 WIRE protein [Homo sapiens]                                96   1e-19
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    95   2e-19
gi|11386183 WAS protein family, member 2 [Homo sapiens]                95   2e-19
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         95   2e-19
gi|192807323 SWI/SNF-related matrix-associated actin-dependent r...    94   3e-19
gi|192807320 SWI/SNF-related matrix-associated actin-dependent r...    94   3e-19
gi|192807318 SWI/SNF-related matrix-associated actin-dependent r...    94   3e-19
gi|192807316 SWI/SNF-related matrix-associated actin-dependent r...    94   3e-19
gi|192807314 SWI/SNF-related matrix-associated actin-dependent r...    94   3e-19
gi|192807312 SWI/SNF-related matrix-associated actin-dependent r...    94   3e-19
gi|21071056 SWI/SNF-related matrix-associated actin-dependent re...    94   3e-19

>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 1325 bits (3429), Expect = 0.0
 Identities = 641/641 (100%), Positives = 641/641 (100%)

Query: 1   MGRRSTSSTKSGKFMNPTDQARKEARKRELKKNKKQRMMVRAAVLKMKDPKQIIRDMEKL 60
           MGRRSTSSTKSGKFMNPTDQARKEARKRELKKNKKQRMMVRAAVLKMKDPKQIIRDMEKL
Sbjct: 1   MGRRSTSSTKSGKFMNPTDQARKEARKRELKKNKKQRMMVRAAVLKMKDPKQIIRDMEKL 60

Query: 61  DEMEFNPVQQPQLNEKVLKDKRKKLRETFERILRLYEKENPDIYKELRKLEVEYEQKRAQ 120
           DEMEFNPVQQPQLNEKVLKDKRKKLRETFERILRLYEKENPDIYKELRKLEVEYEQKRAQ
Sbjct: 61  DEMEFNPVQQPQLNEKVLKDKRKKLRETFERILRLYEKENPDIYKELRKLEVEYEQKRAQ 120

Query: 121 LSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAV 180
           LSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAV
Sbjct: 121 LSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAV 180

Query: 181 SILPLLGHGVPRLPPGRKPPGPPPGPPPPQVVQMYGRKVGFALDLPPRRRDEDMLYSPEL 240
           SILPLLGHGVPRLPPGRKPPGPPPGPPPPQVVQMYGRKVGFALDLPPRRRDEDMLYSPEL
Sbjct: 181 SILPLLGHGVPRLPPGRKPPGPPPGPPPPQVVQMYGRKVGFALDLPPRRRDEDMLYSPEL 240

Query: 241 AQRGHDDDVSSTSEDDGYPEDMDQDKHDDSTDDSDTDKSDGESDGDEFVHRDNGERDNNE 300
           AQRGHDDDVSSTSEDDGYPEDMDQDKHDDSTDDSDTDKSDGESDGDEFVHRDNGERDNNE
Sbjct: 241 AQRGHDDDVSSTSEDDGYPEDMDQDKHDDSTDDSDTDKSDGESDGDEFVHRDNGERDNNE 300

Query: 301 EKKSGLSVRFADMPGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREVEEFSEDDDEDD 360
           EKKSGLSVRFADMPGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREVEEFSEDDDEDD
Sbjct: 301 EKKSGLSVRFADMPGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREVEEFSEDDDEDD 360

Query: 361 SDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPP 420
           SDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPP
Sbjct: 361 SDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPP 420

Query: 421 LRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPP 480
           LRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPP
Sbjct: 421 LRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPP 480

Query: 481 GPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNL 540
           GPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNL
Sbjct: 481 GPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNL 540

Query: 541 IQRPKADDTSAATIEKKATATISAKPQITNPKAEITRFVPTALRVRRENKGATAAPQRKS 600
           IQRPKADDTSAATIEKKATATISAKPQITNPKAEITRFVPTALRVRRENKGATAAPQRKS
Sbjct: 541 IQRPKADDTSAATIEKKATATISAKPQITNPKAEITRFVPTALRVRRENKGATAAPQRKS 600

Query: 601 EDDSAVPLAKAAPKSGPSVPVSVQTKDDVYEAFMKEMEGLL 641
           EDDSAVPLAKAAPKSGPSVPVSVQTKDDVYEAFMKEMEGLL
Sbjct: 601 EDDSAVPLAKAAPKSGPSVPVSVQTKDDVYEAFMKEMEGLL 641


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score =  120 bits (302), Expect = 3e-27
 Identities = 82/163 (50%), Positives = 89/163 (54%), Gaps = 20/163 (12%)

Query: 394 PQSVPPS-QIQAPPMPG-PPPLGP----PPAPPLRPPGPPTGLPPGPPPGA---PPFLRP 444
           P +VP   +   P  PG PPP  P    PP PPL PPGPP   PPGPPP     PP L  
Sbjct: 208 PGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPG--PPGPPPPGQVLPPPLAG 265

Query: 445 PGMPGLRGPLPRLLPPGPPPGRPP-GPP-PGPPPGLPP-GPPPRGPPPRLPPPAPPGIPP 501
           P   G R P P +L PG P G+PP GP  PGPPP +P  GPPP  PPP+  PP PPG  P
Sbjct: 266 PPNRGDRPP-PPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFP 324

Query: 502 PR-PGMMRPPLV----PPLGPAPPGLFPPAPLPNPGVLSAPPN 539
           PR PG + PPL     P L   PPG  PPAP  NP     P N
Sbjct: 325 PRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTN 367



 Score =  113 bits (282), Expect = 6e-25
 Identities = 69/145 (47%), Positives = 74/145 (51%), Gaps = 21/145 (14%)

Query: 393 PPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTG------LPPGPPPGAPPFLRPPG 446
           PP   PP Q+  PP+ GPP  G  P PP+  PG P G      LPPGPPP  P +  PPG
Sbjct: 249 PPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPG 308

Query: 447 -MPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAP---PGI--P 500
             P  +GP P   PPGP P RPPG P GPP  L P P   GPPP  PPPAP   P    P
Sbjct: 309 PPPPQQGPPP---PPGPFPPRPPG-PLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPP 364

Query: 501 PPRPGM-----MRPPLVPPLGPAPP 520
           P   GM       PP   P G  PP
Sbjct: 365 PTNSGMPTSDSRGPPPTDPYGRPPP 389



 Score = 98.6 bits (244), Expect = 2e-20
 Identities = 74/188 (39%), Positives = 83/188 (44%), Gaps = 20/188 (10%)

Query: 364 SEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRP 423
           S+ E QS+K   +     G   A     +   + P         PG  P G     P  P
Sbjct: 165 SQFEMQSRKT-TQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGP 223

Query: 424 PGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLP--RLLPP---GPPPGRPPGPPPGPPPGL 478
            GPP   P G  P  PP L PPG PG  GP P  ++LPP   GPP      PPP   PG 
Sbjct: 224 GGPPPPFPAGQTPPRPP-LGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQ 282

Query: 479 PPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPL---GPAPPGLF---PPAPLPNPG 532
           P G PP GP        PPG PPP PG   PP  PP     P PPG F   PP PL  P 
Sbjct: 283 PFGQPPLGP-------LPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPL 335

Query: 533 VLSAPPNL 540
            L+ PP+L
Sbjct: 336 TLAPPPHL 343



 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 55/138 (39%), Positives = 60/138 (43%), Gaps = 34/138 (24%)

Query: 433 GPPPGAPPFLRPPGMPGLRGPLPRLLPPG---PPPGRPPGPPPGPPPGLPPGPPPRGPPP 489
           GPP G+     P G  G RG  P  +P G   P P  P GPPP  P G  P  PP GPP 
Sbjct: 187 GPPGGSSRAAFPQGGRG-RGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPG 245

Query: 490 RLPPPAPPGIPPPRPGMMRPPLV-----------------------PPLGPAPPGLFPPA 526
              PP PPG  PP PG + PP +                       PPLGP PPG  PP 
Sbjct: 246 ---PPGPPG--PPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPG--PPP 298

Query: 527 PLPNPGVLSAPPNLIQRP 544
           P+P  G    PP   Q P
Sbjct: 299 PVPGYGPPPGPPPPQQGP 316



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 43/92 (46%), Positives = 44/92 (47%), Gaps = 9/92 (9%)

Query: 390 QQAPPQSVPPSQIQAPPMPGPPPLGPP--PAPPLRPPGPPTGLPPGPPPGAPPFLRPPGM 447
           QQ PP   PP     PP P P PLGPP   APP   PGPP G PP  P   P F  PP  
Sbjct: 313 QQGPPP--PPGPF--PPRP-PGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTN 367

Query: 448 PGLRGPLPRLLPPGPPPGRPPGPPPGP--PPG 477
            G+     R  PP  P GRPP    G   PPG
Sbjct: 368 SGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPG 399



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 41/91 (45%), Positives = 42/91 (46%), Gaps = 9/91 (9%)

Query: 461 GPPPG--RPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGP- 517
           GPP G  R   P  G   G  PG  P G   R P PA PG PPP     + P  PPLGP 
Sbjct: 187 GPPGGSSRAAFPQGGRGRGRFPGAVPGGD--RFPGPAGPGGPPPPFPAGQTPPRPPLGPP 244

Query: 518 APPGLFPPAPLPNPGVLSAPPNLIQRPKADD 548
            PPG  PP P P   VL  PP L   P   D
Sbjct: 245 GPPG--PPGPPPPGQVL--PPPLAGPPNRGD 271



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 32/82 (39%), Positives = 36/82 (43%), Gaps = 10/82 (12%)

Query: 393 PPQSVPPSQIQAPP--MPGPPPLGPPPAPPLRPP--------GPPTGLPPGPPPGAPPFL 442
           PP  + P    APP  +PGPPP  PPPAP + P         G PT    GPPP  P   
Sbjct: 327 PPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGR 386

Query: 443 RPPGMPGLRGPLPRLLPPGPPP 464
            PP   G  GP  R +     P
Sbjct: 387 PPPYDRGDYGPPGREMDTARTP 408



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 28/64 (43%), Positives = 30/64 (46%), Gaps = 12/64 (18%)

Query: 159 PGAQPPSILKKTSAYGPPTRAVSILP-LLGHGVP-------RLPPGRKPP----GPPPGP 206
           PG  PP  +      GPP R     P +L  G P        LPPG  PP    GPPPGP
Sbjct: 250 PGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGP 309

Query: 207 PPPQ 210
           PPPQ
Sbjct: 310 PPPQ 313



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 26/77 (33%), Positives = 32/77 (41%), Gaps = 11/77 (14%)

Query: 140 PLPDMPHAPSNILIQDIPLPGAQ----PPSILKKTSAYGPPTRAVSILPLLGHGVPRLPP 195
           P P  P  P  +L   +  P  +    PP +L     +G P       PL     P +P 
Sbjct: 247 PGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLG----PLPPGPPPPVPG 302

Query: 196 GRKPPGPPP---GPPPP 209
              PPGPPP   GPPPP
Sbjct: 303 YGPPPGPPPPQQGPPPP 319



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 20/54 (37%), Positives = 24/54 (44%), Gaps = 18/54 (33%)

Query: 157 PLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPPPQ 210
           PLP   PP +      YGPP              P  PP ++ P PPPGP PP+
Sbjct: 291 PLPPGPPPPV----PGYGPP--------------PGPPPPQQGPPPPPGPFPPR 326



 Score = 33.5 bits (75), Expect = 0.62
 Identities = 24/78 (30%), Positives = 30/78 (38%), Gaps = 16/78 (20%)

Query: 139 IPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRK 198
           + L   PH P        P PGA PP+     + + PPT +         G+P       
Sbjct: 335 LTLAPPPHLPG-------PPPGAPPPAPHVNPAFFPPPTNS---------GMPTSDSRGP 378

Query: 199 PPGPPPGPPPPQVVQMYG 216
           PP  P G PPP     YG
Sbjct: 379 PPTDPYGRPPPYDRGDYG 396



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 22/47 (46%), Positives = 24/47 (51%), Gaps = 10/47 (21%)

Query: 187 GHGVPRLPPGRKPPGPP--PGPPPPQVVQMYGRKVGFALDLPPRRRD 231
           G   PR P G  PPGPP  PGPPPP      G+ +   L  PP R D
Sbjct: 233 GQTPPRPPLG--PPGPPGPPGPPPP------GQVLPPPLAGPPNRGD 271



 Score = 30.8 bits (68), Expect = 4.0
 Identities = 27/72 (37%), Positives = 29/72 (40%), Gaps = 19/72 (26%)

Query: 159 PGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPG---PPP--GPP-----P 208
           PG  PP      +   PP       P LG   P  PPG  PPG   PPP  GPP     P
Sbjct: 223 PGGPPPPF---PAGQTPPR------PPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRP 273

Query: 209 PQVVQMYGRKVG 220
           P  V   G+  G
Sbjct: 274 PPPVLFPGQPFG 285


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score =  115 bits (288), Expect = 1e-25
 Identities = 93/240 (38%), Positives = 111/240 (46%), Gaps = 53/240 (22%)

Query: 393  PPQSVPPSQIQAPP------MPGPPPL---GPPPAPPLR-------PPGPPTGLPPGPP- 435
            PP  +P + I  PP      +P PPPL   G PP PPL        PP P  G+PP PP 
Sbjct: 1032 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1091

Query: 436  PGA--PPFLRPPGMPGLRGPLPRLLP----PGPPP----GRPPGPPPGPPPGLPPGPP-P 484
            PGA  PP   PP +PG+  P P  LP    P PPP    G PP PPP P  G+PP PP P
Sbjct: 1092 PGAGIPP---PPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPPLP 1147

Query: 485  R---GPPPRLP----PPAPP----GIPPPRP----GMMRPPLVPPLGPAPP------GLF 523
            R    PPP LP    PP PP    GIPPP P    G+  PP +P +G  PP      G+ 
Sbjct: 1148 RVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIP 1207

Query: 524  PPAPLPNPGVLSAPPNLIQRPKADDTSAATIEKKATATISAKPQITNPKAEITRFVPTAL 583
            PP PLP  G+  AP   +  P         +       +      T P  ++  F+P  L
Sbjct: 1208 PPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPL 1267



 Score =  115 bits (287), Expect = 2e-25
 Identities = 86/195 (44%), Positives = 97/195 (49%), Gaps = 53/195 (27%)

Query: 393  PPQSVPPSQIQAPP------MPGPPPL---GPPPAPPLR-------PPGPPTGLPPGPP- 435
            PP  +P + I  PP      +P PPPL   G PP PPL        PP P  G+PP PP 
Sbjct: 988  PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1047

Query: 436  PGA--PPFLRPPGMPGLRGPLPRLLP----PGPPP----GRPPGPPPGPPPGLPPGPPPR 485
            PGA  PP   PP +PG   P P  LP    P PPP    G PP PPP P  G+PP PP  
Sbjct: 1048 PGAGIPP---PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPPLP 1103

Query: 486  G----PPPRLP----PPAPP----GIPPPRP----GMMRPPLVPPLGPAPP------GLF 523
            G    PPP LP    PP PP    GIPPP P    G+  PP +P +G  PP      G+ 
Sbjct: 1104 GVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIP 1163

Query: 524  PPAPLPNPGVLSAPP 538
            PP PLP  G+   PP
Sbjct: 1164 PPPPLPGAGIPPPPP 1178



 Score =  114 bits (284), Expect = 4e-25
 Identities = 87/195 (44%), Positives = 97/195 (49%), Gaps = 53/195 (27%)

Query: 393  PPQSVPPSQI-QAPPMPG-----PPPLG------PPPAP----PLRPPGPPTGLPPGPP- 435
            PP  +P + I   PP+PG     PPPL       PPP P    PL PP P  G+PP PP 
Sbjct: 922  PPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPL 981

Query: 436  PGA--PPFLRPPGMPGLRGPLPRLLP----PGPPP----GRPPGPPPGPPPGLPPGPPPR 485
            PGA  PP   PP +PG   P P  LP    P PPP    G PP PPP P  G+PP PP  
Sbjct: 982  PGAGIPP---PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPPLP 1037

Query: 486  G----PPPRLP----PPAPP----GIPPPRP----GMMRPPLVPPLGPAPP------GLF 523
            G    PPP LP    PP PP    GIPPP P    G+  PP +P  G  PP      G+ 
Sbjct: 1038 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1097

Query: 524  PPAPLPNPGVLSAPP 538
            PP PLP  G+   PP
Sbjct: 1098 PPPPLPGVGIPPPPP 1112



 Score =  109 bits (272), Expect = 9e-24
 Identities = 83/196 (42%), Positives = 97/196 (49%), Gaps = 46/196 (23%)

Query: 383  TSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLR-------PPGPPTGLPPGPP 435
            T  +++  Q PP  +  +++  PP P  P  G PP PPL        PP P  G+PP PP
Sbjct: 890  TLPSTAIPQPPP--LQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPP 947

Query: 436  -PGA--PPFLRPPGMPGLRGPLPRLLP----PGPPP----GRPPGPPPGPPPGLPPGPPP 484
             PGA  PP   PP +PG   PLP  LP    P PPP    G PP PPP P  G+PP PP 
Sbjct: 948  LPGAAIPP---PPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPPL 1003

Query: 485  RG----PPPRLP------PPAPP--GIPPPRP----GMMRPPLVPPLGPAPP------GL 522
             G    PPP LP      PP  P  GIPPP P    G+  PP +P  G  PP      G+
Sbjct: 1004 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1063

Query: 523  FPPAPLPNPGVLSAPP 538
             PP PLP  G+   PP
Sbjct: 1064 PPPPPLPGAGIPPPPP 1079



 Score =  105 bits (263), Expect = 1e-22
 Identities = 77/180 (42%), Positives = 87/180 (48%), Gaps = 35/180 (19%)

Query: 393  PPQSVPPSQIQAPP---MPGPPPL-GPPPAPPLRPPGPPTGLPPGPP-PGAPPFLRPPGM 447
            PP  +P   +   P   +P PPPL G    PP  PP P  G+PP PP PGA     PP +
Sbjct: 879  PPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPP-L 937

Query: 448  PGLRGPLPRLLPPG---PPPGRP----PGPPPGPPPGLPPGPPPRG----PPPRLP---- 492
            PG   P P  LP     PPP  P    P PPP P  G+PP PP  G    PPP LP    
Sbjct: 938  PGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 997

Query: 493  PPAPP----GIPPPRP----GMMRPPLVPPLGPAPP------GLFPPAPLPNPGVLSAPP 538
            PP PP    GIPPP P    G+  PP +P  G  PP      G+ PP PLP  G+   PP
Sbjct: 998  PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1057



 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 76/191 (39%), Positives = 85/191 (44%), Gaps = 43/191 (22%)

Query: 376  EESHSDGTSTASSQQQAPPQSVP-PSQIQAPPMPG----PPPLGPPPAPPLRPPGPPTG- 429
            + SH    S+A       P   P P    +  MPG    PPP  PPP P +  P  P+  
Sbjct: 838  QTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPP--PPPLPGMTVPTLPSTA 895

Query: 430  ------------LPPGPPP----GAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPG 473
                        LPP PPP    G PP   PP +PG  G LP  LPP P  G PP PPP 
Sbjct: 896  IPQPPPLQGTEMLPPPPPPLPGAGIPP---PPPLPGA-GILP--LPPLPGAGIPP-PPPL 948

Query: 474  PPPGLPPGPPPRGPPPRLPPPAP-PGIPPPRPGMMRPPL----VPPLGPAPPGLF-PPAP 527
            P   +PP PP  G    LPPP P  GIPPP      PPL    +PP  P P     PP P
Sbjct: 949  PGAAIPPPPPLPGAGIPLPPPLPGAGIPPP------PPLPGAGIPPPPPLPGAGIPPPPP 1002

Query: 528  LPNPGVLSAPP 538
            LP  G+   PP
Sbjct: 1003 LPGAGIPPPPP 1013



 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 62/154 (40%), Positives = 69/154 (44%), Gaps = 35/154 (22%)

Query: 393  PPQSVPPSQIQAPP------MPGPPPL---GPPPAPPLR-------PPGPPTGLPPGPP- 435
            PP  +P + I  PP      +P PPPL   G PP PPL        PP P  G+PP PP 
Sbjct: 1131 PPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPL 1190

Query: 436  --PGAPPFLRPPGMPGLRGPLPRLLPP-GPPPGRPPGPPPGPPPGLPPGPPPRGP---PP 489
               G PP   PP +PG   P P  LP  G PP   P   P PPPG    PPP  P   PP
Sbjct: 1191 PGVGIPP---PPPLPGAGIPPPPPLPGMGIPPAPAP---PLPPPGTGIPPPPLLPVSGPP 1244

Query: 490  RLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLF 523
             LP      +P P+     PP      P P GLF
Sbjct: 1245 LLPQVGSSTLPTPQVCGFLPP------PLPSGLF 1272



 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 101/424 (23%), Positives = 144/424 (33%), Gaps = 131/424 (30%)

Query: 231  DEDMLYS-PELAQRGHDDDVSSTSEDDGYPEDMDQDKHDDSTDDSDTDKSDGESDGDEFV 289
            D+D LY+   ++Q  H  D S    +  +P  +          D +    D E++    V
Sbjct: 594  DQDQLYTWAAVSQPTHSLDYS----EGQFPRRVPSMGPPSKPPDEEHRLEDAETESQSAV 649

Query: 290  HRDNGERDNNEEKKSGLSVRFADMPGKSRKKKKNMKELTPLQAMMLRMAGQE--IPEEGR 347
                 +R +  +K+        DM  + +       E T ++ +  ++A  E   P    
Sbjct: 650  SETPQKRSDAVQKE------VVDMKSEGQATVIQQLEQT-IEDLRTKIAELERQYPALDT 702

Query: 348  EVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPM 407
            EV    +  +   +   +   ++ +  ++E        A S Q +P +      +  PP+
Sbjct: 703  EVASGHQGLENGVTASGDVCLEALRLEEKEVRHHRILEAKSIQTSPTEE--GGVLTLPPV 760

Query: 408  PGPPPLGPPPAPPLRPPGPPT----------------------------GLPPGPP---- 435
             G P  G PP PP    GP T                              PP PP    
Sbjct: 761  DGLP--GRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLW 818

Query: 436  ------PGAPP-------------------------FLRPPGMP-----------GLRGP 453
                  PG+ P                            PP +P           G+  P
Sbjct: 819  SAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPP 878

Query: 454  LPRLLP------------PGPPPGR-----PPGPPPGPPPGLPPGPPPRG----PPPRLP 492
             P  LP            P PPP +     PP PPP P  G+PP PP  G    P P LP
Sbjct: 879  PPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLP 938

Query: 493  ----PPAPP----GIPPPRP----GMMRPPLVPPLGPAPP------GLFPPAPLPNPGVL 534
                PP PP     IPPP P    G+  PP +P  G  PP      G+ PP PLP  G+ 
Sbjct: 939  GAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 998

Query: 535  SAPP 538
              PP
Sbjct: 999  PPPP 1002



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 30/78 (38%), Positives = 34/78 (43%), Gaps = 16/78 (20%)

Query: 141  LPDMPHAPSNILIQDIPLPGA--QPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPP--- 195
            +P  P  P   +    PLPGA   PP  L +     PP       PL G G+P  PP   
Sbjct: 1118 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPP-------PLPGAGIPPPPPLPG 1170

Query: 196  -GRKPPGPPPG---PPPP 209
             G  PP P PG   PPPP
Sbjct: 1171 AGIPPPPPLPGVGIPPPP 1188



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 30/78 (38%), Positives = 35/78 (44%), Gaps = 16/78 (20%)

Query: 141 LPDMPHAPSNILIQDIPLPGA--QPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPP--- 195
           +P  P  P   ++   PLPGA   PP  L   +   PP       PL G G+P  PP   
Sbjct: 920 IPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPP-------PLPGAGIPLPPPLPG 972

Query: 196 -GRKPPGPPPG---PPPP 209
            G  PP P PG   PPPP
Sbjct: 973 AGIPPPPPLPGAGIPPPP 990



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 33/80 (41%), Positives = 35/80 (43%), Gaps = 18/80 (22%)

Query: 139  IPLPDMPHAPSNILIQDIPLPGA--QPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPP- 195
            IPLP  P  P   +    PLPGA   PP  L       PP       PL G G+P  PP 
Sbjct: 964  IPLP--PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP-------PLPGAGIPPPPPL 1014

Query: 196  ---GRKPPGPPPG---PPPP 209
               G  PP P PG   PPPP
Sbjct: 1015 PGAGIPPPPPLPGAGIPPPP 1034



 Score = 38.5 bits (88), Expect = 0.019
 Identities = 32/80 (40%), Positives = 36/80 (45%), Gaps = 19/80 (23%)

Query: 139  IPLPDMPHAPSNILIQDIPLPGAQ--PPSILKKTSAYGPPTRAVSILPLLGHGVPRLPP- 195
            +PLP +P A    +    PLPGA   PP  L       PP       PL G G+P  PP 
Sbjct: 932  LPLPPLPGAG---IPPPPPLPGAAIPPPPPLPGAGIPLPP-------PLPGAGIPPPPPL 981

Query: 196  ---GRKPPGPPPG---PPPP 209
               G  PP P PG   PPPP
Sbjct: 982  PGAGIPPPPPLPGAGIPPPP 1001



 Score = 38.1 bits (87), Expect = 0.025
 Identities = 33/88 (37%), Positives = 37/88 (42%), Gaps = 18/88 (20%)

Query: 140 PLPDM--PHAPSNILIQDIPLPGAQ-----PPSILKKTSAYGPPTRAVSILPLL---GHG 189
           PLP M  P  PS  + Q  PL G +     PP +        PP     ILPL    G G
Sbjct: 882 PLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAG 941

Query: 190 VPRLP--PGRKPPGPPPGP------PPP 209
           +P  P  PG   P PPP P      PPP
Sbjct: 942 IPPPPPLPGAAIPPPPPLPGAGIPLPPP 969



 Score = 38.1 bits (87), Expect = 0.025
 Identities = 30/78 (38%), Positives = 33/78 (42%), Gaps = 16/78 (20%)

Query: 141  LPDMPHAPSNILIQDIPLPGA--QPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPP--- 195
            +P  P  P   +    PLPGA   PP  L       PP       PL G G+P  PP   
Sbjct: 975  IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP-------PLPGAGIPPPPPLPG 1027

Query: 196  -GRKPPGPPPG---PPPP 209
             G  PP P PG   PPPP
Sbjct: 1028 AGIPPPPPLPGAGIPPPP 1045



 Score = 38.1 bits (87), Expect = 0.025
 Identities = 30/78 (38%), Positives = 33/78 (42%), Gaps = 16/78 (20%)

Query: 141  LPDMPHAPSNILIQDIPLPGA--QPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPP--- 195
            +P  P  P   +    PLPGA   PP  L       PP       PL G G+P  PP   
Sbjct: 986  IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP-------PLPGAGIPPPPPLPG 1038

Query: 196  -GRKPPGPPPG---PPPP 209
             G  PP P PG   PPPP
Sbjct: 1039 AGIPPPPPLPGAGIPPPP 1056



 Score = 38.1 bits (87), Expect = 0.025
 Identities = 30/78 (38%), Positives = 33/78 (42%), Gaps = 16/78 (20%)

Query: 141  LPDMPHAPSNILIQDIPLPGA--QPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPP--- 195
            +P  P  P   +    PLPGA   PP  L       PP       PL G G+P  PP   
Sbjct: 997  IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP-------PLPGAGIPPPPPLPG 1049

Query: 196  -GRKPPGPPPG---PPPP 209
             G  PP P PG   PPPP
Sbjct: 1050 AGIPPPPPLPGAGIPPPP 1067



 Score = 38.1 bits (87), Expect = 0.025
 Identities = 30/78 (38%), Positives = 33/78 (42%), Gaps = 16/78 (20%)

Query: 141  LPDMPHAPSNILIQDIPLPGA--QPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPP--- 195
            +P  P  P   +    PLPGA   PP  L       PP       PL G G+P  PP   
Sbjct: 1008 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP-------PLPGAGIPPPPPLPG 1060

Query: 196  -GRKPPGPPPG---PPPP 209
             G  PP P PG   PPPP
Sbjct: 1061 AGIPPPPPLPGAGIPPPP 1078



 Score = 38.1 bits (87), Expect = 0.025
 Identities = 30/78 (38%), Positives = 33/78 (42%), Gaps = 16/78 (20%)

Query: 141  LPDMPHAPSNILIQDIPLPGA--QPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPP--- 195
            +P  P  P   +    PLPGA   PP  L       PP       PL G G+P  PP   
Sbjct: 1019 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP-------PLPGAGIPPPPPLPG 1071

Query: 196  -GRKPPGPPPG---PPPP 209
             G  PP P PG   PPPP
Sbjct: 1072 AGIPPPPPLPGAGIPPPP 1089



 Score = 38.1 bits (87), Expect = 0.025
 Identities = 30/78 (38%), Positives = 33/78 (42%), Gaps = 16/78 (20%)

Query: 141  LPDMPHAPSNILIQDIPLPGA--QPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPP--- 195
            +P  P  P   +    PLPGA   PP  L       PP       PL G G+P  PP   
Sbjct: 1030 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP-------PLPGAGIPPPPPLPG 1082

Query: 196  -GRKPPGPPPG---PPPP 209
             G  PP P PG   PPPP
Sbjct: 1083 AGIPPPPPLPGAGIPPPP 1100



 Score = 38.1 bits (87), Expect = 0.025
 Identities = 30/78 (38%), Positives = 33/78 (42%), Gaps = 16/78 (20%)

Query: 141  LPDMPHAPSNILIQDIPLPGA--QPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPP--- 195
            +P  P  P   +    PLPGA   PP  L       PP       PL G G+P  PP   
Sbjct: 1041 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP-------PLPGAGIPPPPPLPG 1093

Query: 196  -GRKPPGPPPG---PPPP 209
             G  PP P PG   PPPP
Sbjct: 1094 AGIPPPPPLPGVGIPPPP 1111



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 30/78 (38%), Positives = 33/78 (42%), Gaps = 16/78 (20%)

Query: 141  LPDMPHAPSNILIQDIPLPGA--QPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPP--- 195
            +P  P  P   +    PLPGA   PP  L       PP       PL G G+P  PP   
Sbjct: 953  IPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPP-------PLPGAGIPPPPPLPG 1005

Query: 196  -GRKPPGPPPG---PPPP 209
             G  PP P PG   PPPP
Sbjct: 1006 AGIPPPPPLPGAGIPPPP 1023



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 30/78 (38%), Positives = 33/78 (42%), Gaps = 16/78 (20%)

Query: 141  LPDMPHAPSNILIQDIPLPGA--QPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPP--- 195
            +P  P  P   +    PLPGA   PP  L       PP       PL G G+P  PP   
Sbjct: 1096 IPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPP-------PLPGAGIPPPPPLPR 1148

Query: 196  -GRKPPGPPPG---PPPP 209
             G  PP P PG   PPPP
Sbjct: 1149 VGIPPPPPLPGAGIPPPP 1166



 Score = 37.0 bits (84), Expect = 0.056
 Identities = 28/74 (37%), Positives = 31/74 (41%), Gaps = 15/74 (20%)

Query: 141  LPDMPHAPSNILIQDIPLPGA--QPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRK 198
            +P  P  P   +    PLPG    PP  L       PP       PL G G+   PP   
Sbjct: 1173 IPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPP-------PLPGMGI---PPAPA 1222

Query: 199  PPGPPPG---PPPP 209
            PP PPPG   PPPP
Sbjct: 1223 PPLPPPGTGIPPPP 1236



 Score = 37.0 bits (84), Expect = 0.056
 Identities = 25/64 (39%), Positives = 27/64 (42%), Gaps = 7/64 (10%)

Query: 393  PPQSVPPSQIQAPPMPG----PPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMP 448
            P   +PP+     P PG    PPPL P   PPL    P  G    P P    FL PP   
Sbjct: 1213 PGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLL---PQVGSSTLPTPQVCGFLPPPLPS 1269

Query: 449  GLRG 452
            GL G
Sbjct: 1270 GLFG 1273



 Score = 36.2 bits (82), Expect = 0.096
 Identities = 34/95 (35%), Positives = 38/95 (40%), Gaps = 15/95 (15%)

Query: 141  LPDMPHAPSNILIQDIPLPGA--QPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPP--- 195
            +P  P  P   +    PLPGA   PP  L       PP       PL G G+P  PP   
Sbjct: 1140 IPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPP-------PLPGVGIPPPPPLPG 1192

Query: 196  -GRKPPGPPP--GPPPPQVVQMYGRKVGFALDLPP 227
             G  PP P P  G PPP  +   G     A  LPP
Sbjct: 1193 VGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPP 1227



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 30/83 (36%), Positives = 34/83 (40%), Gaps = 19/83 (22%)

Query: 141  LPDMPHAPSNILIQDIPLPGA--QPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPP--- 195
            +P  P  P   +    PLPGA   PP  L       PP       PL G G+P  PP   
Sbjct: 1074 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPP-------PLPGAGIPPPPPLPG 1126

Query: 196  -GRKPPGP------PPGPPPPQV 211
             G  PP P      PP PP P+V
Sbjct: 1127 AGIPPPPPLPGAGIPPPPPLPRV 1149



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 44/157 (28%), Positives = 52/157 (33%), Gaps = 20/157 (12%)

Query: 376 EESHSDGTSTASSQQQAPPQSVP--PSQIQAPPMPGPPPLGPPPAPPLRPPGP------- 426
           E   S  T  A S     P+S+   P + Q PP PG  P+   P+ P   P         
Sbjct: 262 EAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSST 321

Query: 427 ----PTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLL-PPGPPPGRPPGPPPG--PPPGLP 479
               P   P     GAP  +R  G     G        P   PG    P  G   P  L 
Sbjct: 322 AFPFPEAGPGEEAAGAP--VRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLG 379

Query: 480 PGPPPRGPPPRLPPPAP-PGIPPPRPGMMRP-PLVPP 514
             P      P  P  A  PG P P     +P PL+ P
Sbjct: 380 EEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITP 416



 Score = 32.0 bits (71), Expect = 1.8
 Identities = 33/102 (32%), Positives = 37/102 (36%), Gaps = 7/102 (6%)

Query: 436 PGAPPFLRPPGMPGLRGPLPR-LLPPGPPPGRPPGPPPGPP--PGLPPGPPPRGPPPRLP 492
           P APP    P  PG    L R LL P    G  PG P        L   P      PR P
Sbjct: 232 PAAPPTAVSP-QPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREP 290

Query: 493 --PPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPG 532
             PP+P G+P      + P   P    +P     P P   PG
Sbjct: 291 QQPPSPGGLPVSEAPSL-PAAQPAAKDSPSSTAFPFPEAGPG 331


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score =  109 bits (273), Expect = 7e-24
 Identities = 85/229 (37%), Positives = 100/229 (43%), Gaps = 52/229 (22%)

Query: 364 SEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRP 423
           S A+  ++   +EES S     A + Q APPQ    ++ Q PP P   P GPPP    +P
Sbjct: 14  SSAQNLNEDVSQEESPS---LIAGNPQGAPPQG--GNKPQGPPSPPGKPQGPPPQGGNQP 68

Query: 424 PGPPT--GLPPGPPP-------GAPPFLRPPGMP--GLRGPLPRLLP------------- 459
            GPP   G P GPPP       G PP  +P G P  G +   PR  P             
Sbjct: 69  QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQ 128

Query: 460 ---PGPPPGRPPGPPPG--------PPPGLPPGPPPRGP----PPRLPPPAPPGIPPP-- 502
              P PPPG+P GPPP         PPPG P GPPP+G       R PP  P G PP   
Sbjct: 129 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGG 188

Query: 503 -RPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTS 550
            +P    PP   P GP P G   P   P PG    PP     P+ D+ S
Sbjct: 189 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP-----PQGDNKS 232



 Score =  107 bits (268), Expect = 3e-23
 Identities = 79/196 (40%), Positives = 89/196 (45%), Gaps = 47/196 (23%)

Query: 381 DGTSTASSQQQAPPQSVPP---SQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPG 437
           D  S ++      PQ  PP   +Q Q PP P   P GPPP    +P GPP   PPG P G
Sbjct: 229 DNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP---PPGKPQG 285

Query: 438 APP--------FLRPPGMPGLRGPLPR----LLPPGPPPGRPPGPPPG--------PPPG 477
            PP           PPG P  +GP P+       P PPPG+P GPPP         PPPG
Sbjct: 286 PPPQGGSKSRSSRSPPGKP--QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 343

Query: 478 LPPGPPPRG---------PP--PRLPPPA----PPGIPPPRPGMMRPPLVPPLGPAPPGL 522
            P GPPP+G         PP  P+ PP      P G PPP  G  + P  PP G  P G 
Sbjct: 344 KPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAG-QPQG- 401

Query: 523 FPPAPLPNPGVLSAPP 538
            PP P P  G  S PP
Sbjct: 402 -PPRP-PQGGRPSRPP 415



 Score =  106 bits (265), Expect = 6e-23
 Identities = 80/196 (40%), Positives = 89/196 (45%), Gaps = 51/196 (26%)

Query: 394 PQSVPP---SQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPP--------FL 442
           PQ  PP   +Q Q PP P   P GPPP    +P GPP   PPG P G PP          
Sbjct: 118 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP---PPGKPQGPPPQGDNKSRSSR 174

Query: 443 RPPGMPGLRGPLPR----LLPPGPPPGRPPGPPPG--------PPPGLPPGPPPRG---- 486
            PPG P  +GP P+       P PPPG+P GPPP         PPPG P GPPP+G    
Sbjct: 175 SPPGKP--QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKS 232

Query: 487 -----PP--PRLPPPA---PPGIPPPRPGMMRPPLV----PPLGPAPPGLFPPAPLPNPG 532
                PP  P+ PPP     P  PPP PG  + P       P GP PPG  P  P P  G
Sbjct: 233 QSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK-PQGPPPQGG 291

Query: 533 VLS----APPNLIQRP 544
             S    +PP   Q P
Sbjct: 292 SKSRSSRSPPGKPQGP 307



 Score =  105 bits (262), Expect = 1e-22
 Identities = 74/187 (39%), Positives = 82/187 (43%), Gaps = 33/187 (17%)

Query: 381 DGTSTASSQQQAPPQSVPP---SQIQAPPMPGPPPLGPPP-------APPLRPPGPPTGL 430
           D  S +S      PQ  PP   +Q Q PP P   P GPPP        PP  PPG P G 
Sbjct: 167 DNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP--PPGKPQGP 224

Query: 431 PPGPPPGAPPFLRPPGMPGLRGPLP----RLLPPGPPPGRPPGPPP--------GPPPGL 478
           PP     +     PPG P  +GP P    +   P PPPG+P GPPP         PPPG 
Sbjct: 225 PPQGDNKSQSARSPPGKP--QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 282

Query: 479 PPGPPPRG----PPPRLPPPAPPGIPPP---RPGMMRPPLVPPLGPAPPGLFPPAPLPNP 531
           P GPPP+G       R PP  P G PP    +P    PP   P GP P G   P   P P
Sbjct: 283 PQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 342

Query: 532 GVLSAPP 538
           G    PP
Sbjct: 343 GKPQGPP 349



 Score =  102 bits (254), Expect = 1e-21
 Identities = 79/208 (37%), Positives = 85/208 (40%), Gaps = 62/208 (29%)

Query: 388 SQQQAPPQSVPPSQIQAPPMPG------PPPLGPPPAPP------LRPPGPPTGLPPGPP 435
           +Q Q PP   PP + Q PP  G      PPP G P  PP       R    P G P GPP
Sbjct: 127 NQPQGPPP--PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPP 184

Query: 436 P-------GAPPFLRPPGMP---------GLRGPLPRLLPPGP-------------PPGR 466
           P       G PP   PPG P           +GP P   P GP             PPG+
Sbjct: 185 PQGGNQPQGPPP---PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGK 241

Query: 467 PPGPP---------PGPPPGLPPGPPPRG--PPPRLPPPAPPGIPPPRPG----MMRPPL 511
           P GPP         P PPPG P GPPP+G   P   PPP  P  PPP+ G      R P 
Sbjct: 242 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPP 301

Query: 512 VPPLGPAPP-GLFPPAPLPNPGVLSAPP 538
             P GP P  G  P  P P PG    PP
Sbjct: 302 GKPQGPPPQGGNQPQGPPPPPGKPQGPP 329



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 27/80 (33%), Positives = 31/80 (38%), Gaps = 16/80 (20%)

Query: 140 PLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRA-VSILPLLGHGVPRLPP--- 195
           P P  P  P        P  G +P          GPP +   S  P    G P+ PP   
Sbjct: 73  PPPGKPQGPP-------PQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG 125

Query: 196 GRKPPGPPPGP-----PPPQ 210
           G +P GPPP P     PPPQ
Sbjct: 126 GNQPQGPPPPPGKPQGPPPQ 145



 Score = 30.8 bits (68), Expect = 4.0
 Identities = 22/59 (37%), Positives = 24/59 (40%), Gaps = 20/59 (33%)

Query: 160 GAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPP---GRKPPGPPPGP-----PPPQ 210
           G  P    K  SA  PP            G P+ PP   G +P GPPP P     PPPQ
Sbjct: 223 GPPPQGDNKSQSARSPP------------GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 269



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 18/50 (36%), Positives = 20/50 (40%), Gaps = 3/50 (6%)

Query: 159 PGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPP 208
           P   PP    +     PP       P  G   P+ PP   PPG P GPPP
Sbjct: 57  PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP---PPGKPQGPPP 103



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 18/50 (36%), Positives = 20/50 (40%), Gaps = 3/50 (6%)

Query: 159 PGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPP 208
           P   PP    +     PP       P  G   P+ PP   PPG P GPPP
Sbjct: 118 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP---PPGKPQGPPP 164



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 18/50 (36%), Positives = 20/50 (40%), Gaps = 3/50 (6%)

Query: 159 PGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPP 208
           P   PP    +     PP       P  G   P+ PP   PPG P GPPP
Sbjct: 180 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP---PPGKPQGPPP 226



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 18/50 (36%), Positives = 20/50 (40%), Gaps = 3/50 (6%)

Query: 159 PGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPP 208
           P   PP    +     PP       P  G   P+ PP   PPG P GPPP
Sbjct: 242 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP---PPGKPQGPPP 288



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 18/50 (36%), Positives = 20/50 (40%), Gaps = 3/50 (6%)

Query: 159 PGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPP 208
           P   PP    +     PP       P  G   P+ PP   PPG P GPPP
Sbjct: 304 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP---PPGKPQGPPP 350



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 21/59 (35%), Positives = 24/59 (40%), Gaps = 20/59 (33%)

Query: 160 GAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPP---GRKPPGPPPGP-----PPPQ 210
           G  P    K  S+  PP            G P+ PP   G +P GPPP P     PPPQ
Sbjct: 161 GPPPQGDNKSRSSRSPP------------GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 207



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 21/59 (35%), Positives = 24/59 (40%), Gaps = 20/59 (33%)

Query: 160 GAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPP---GRKPPGPPPGP-----PPPQ 210
           G  P    K  S+  PP            G P+ PP   G +P GPPP P     PPPQ
Sbjct: 285 GPPPQGGSKSRSSRSPP------------GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 331


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score =  108 bits (271), Expect = 1e-23
 Identities = 82/269 (30%), Positives = 103/269 (38%), Gaps = 50/269 (18%)

Query: 393 PPQSVPPSQIQAPPM-----PGPP------------PLGPPPAPPLRPPGPPTGLPPGPP 435
           PP   PPS   +PP+     P P             P  PPP+PP++ P  P   PP  P
Sbjct: 628 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 687

Query: 436 PGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPA 495
              PP   PP +       P L  P  PP  PP  P   PP  P  PPP   PP   PP+
Sbjct: 688 SATPPSQAPPSLAA-----PPLQVPPSPPASPPMSPSATPP--PQAPPPLAAPPLQVPPS 740

Query: 496 PPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAP---LP----------NPGVLSAPP-NLI 541
           PP  PP  P    PP VPPL  APP   PP+P   LP           P  L+ PP   +
Sbjct: 741 PPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQAL 800

Query: 542 QRPKADDTSAATIEKKATATIS--------AKPQITNPKAEITRFVPTALRVRRENKGAT 593
             P A     A     A+  +S        A P +  P  ++    P +  ++   +  T
Sbjct: 801 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT 860

Query: 594 AAPQRKSEDDSAVPLAKAAPKSGPSVPVS 622
             P    +   + P    A   GP  P S
Sbjct: 861 PGP----DTSVSGPRLTLALAPGPPPPPS 885



 Score = 97.1 bits (240), Expect = 5e-20
 Identities = 84/272 (30%), Positives = 107/272 (39%), Gaps = 50/272 (18%)

Query: 389 QQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMP 448
           Q  + P + P   ++ PP P P PL  PP+P   PP         PPP APP L  P + 
Sbjct: 547 QTASAPLTTP--HLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQ 604

Query: 449 GLRGP-----------------LPRLLPPGPPPGRPP-----GPPPGPPPGL-------- 478
           GL  P                 LP L  P  PP  PP      P P  P  L        
Sbjct: 605 GLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 664

Query: 479 ---PPGPPPRGP--PPRLPPPAPPGIPPPR--PGMMRPPL-VPPLGPAPPGLFPPA--PL 528
              PP PP + P  PP  PP +P   PP +  P +  PPL VPP  PA P + P A  P 
Sbjct: 665 FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 724

Query: 529 PNPGVLSAPPNLIQRPKADDTSAATIEKKATATISAKPQITNPKAEITRFVPTALRVRRE 588
             P  L+APP  +Q P +   S   +   AT      P +  P  ++    P +L +   
Sbjct: 725 QAPPPLAAPP--LQVPPSPPAS-PPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPM--- 778

Query: 589 NKGATAAPQRKSEDDSAVPLAKAAPKSGPSVP 620
                A P  ++    A P  +A P    S P
Sbjct: 779 --SPLAKPPPQAPPALATPPLQALPSPPASFP 808



 Score = 97.1 bits (240), Expect = 5e-20
 Identities = 90/271 (33%), Positives = 114/271 (42%), Gaps = 46/271 (16%)

Query: 384 STASSQQQAPPQSVPPSQIQAPPMPG---PPPLGPPP--APPLR-PPGPPTGLPPGPPPG 437
           S A     APP  VPPS   +PPM     PPP  PPP  APPL+ PP PP       PP 
Sbjct: 693 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPAS-----PPM 747

Query: 438 APPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPG---PPPR---GPPPRL 491
           +P    PP +P L    P  +PP PP   P  P   PPP  PP    PP +    PP   
Sbjct: 748 SPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASF 807

Query: 492 P-----------PPAPPGIPPPR-PGMMRPPL--VPPLGPAPPGLFPPAPLPNPGVLSAP 537
           P           P +P   PPP+ P ++  PL  VPP  PA P L  P   P PG    P
Sbjct: 808 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG----P 863

Query: 538 PNLIQRPKADDTSA----ATIEKKATATISAKPQITNPKAEITRFVPTALRVRRENK--G 591
              +  P+     A        +  ++T+S  P +    +  T   P  LR        G
Sbjct: 864 DTSVSGPRLTLALAPGPPPPPSRSPSSTLSG-PDLAGHSSSATS-TPEELRGYDSGPEGG 921

Query: 592 ATAAPQRKSEDDSAVPLAKAAPKSGPSVPVS 622
           A A+P   +E  +  P   AA   GP+ P++
Sbjct: 922 AAASPPPDAELAACHP---AAWSRGPAPPLA 949



 Score = 96.3 bits (238), Expect = 8e-20
 Identities = 84/266 (31%), Positives = 103/266 (38%), Gaps = 48/266 (18%)

Query: 385 TASSQQQAPPQSVPPSQIQAPPMPG--PPPLGPPPAPPLRPPG----PPTGLPPGPPPGA 438
           T SS    PPQ+  P  + +PP+ G   PPL P   PP + P     PP   PP PP  A
Sbjct: 583 TPSSIATPPPQA--PPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPP--A 638

Query: 439 PPFLRPPGMPGLRGP---------LPRLLPPGPP---PGRPPGPPPGPPPGLPP--GPPP 484
            P L P   P  + P          P   PP PP   P  PP  PP  P   PP   PP 
Sbjct: 639 SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 698

Query: 485 RGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPN-------------P 531
              PP   PP+PP  PP  P    PP  PP   APP   PP+P  +             P
Sbjct: 699 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVP 758

Query: 532 GVLSAPPNLIQRPKADDTSAATIEKKATATISAKPQITNPKAEITRFVPTALRVRRENKG 591
            +L+APP  +Q P +   S   +   A     A P +  P  +     P +         
Sbjct: 759 PLLAAPP--LQVPPSPPAS-LPMSPLAKPPPQAPPALATPPLQALPSPPASF-------- 807

Query: 592 ATAAPQRKSEDDSAVPLAKAAPKSGP 617
              AP   S      PLA   P++ P
Sbjct: 808 PGQAPFSPSASLPMSPLATPPPQAPP 833



 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 71/246 (28%), Positives = 93/246 (37%), Gaps = 31/246 (12%)

Query: 392 APPQ-SVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGL 450
           APP    PP+ +  PP+   P L PPP      P     L   P P   P   PP     
Sbjct: 519 APPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPS---- 574

Query: 451 RGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPR--PGMMR 508
               P   PP   P     PPP  PP L   PP +G P   PP +P   PPP+  P +  
Sbjct: 575 ----PLTTPPPETPSSIATPPPQAPPAL-ASPPLQGLPS--PPLSPLATPPPQAPPXLAL 627

Query: 509 PPL-VPPLGPAPPGLFP---PAP-LPN-------PGVLSAPPNLIQRPKADDTSAATIEK 556
           PPL  PP  PA P L P   P+P  PN           S PP+   +      ++  +  
Sbjct: 628 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 687

Query: 557 KATATISAKPQITNPKAEITRFVPTALRVRRENKGATAAPQRKSEDDSAVPLAKAAPKSG 616
            AT    A P +  P  ++    P +          +A P  ++    A P  +  P   
Sbjct: 688 SATPPSQAPPSLAAPPLQVPPSPPAS-----PPMSPSATPPPQAPPPLAAPPLQVPPSPP 742

Query: 617 PSVPVS 622
            S P+S
Sbjct: 743 ASPPMS 748



 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 81/305 (26%), Positives = 107/305 (35%), Gaps = 22/305 (7%)

Query: 328 TPLQAMMLRMAGQEI----PEEGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGT 383
           +P  A   R AG E+    P         +E   +  S  SE              S G 
Sbjct: 173 SPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG 232

Query: 384 STASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLR 443
                  ++   S  P  + +P   GP   G P AP       P GL    PP   P  R
Sbjct: 233 GLQRPASRSLSSSATP--LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP-PR 289

Query: 444 PPGMPGLRGPL---PRLLP-PGPPPGRPPGPPPGP----PPGLPPGPPPRGPPPRLPPPA 495
               P L GPL   P   P P     RP  PP       P  LPP PP   P P  PP  
Sbjct: 290 KDAAPAL-GPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPS- 347

Query: 496 PPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSAATIE 555
            P  PP    +  PP  PP   APP +  P     P + + PP  +       +  A   
Sbjct: 348 -PSAPPSLQTLPSPPATPP-SQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPS 405

Query: 556 KKATATISAKPQITNPKAEITRFVPTALRVRRENKGATAAPQRKSEDDSAVPLAKAAPKS 615
             A +++ A   + +P  + T    T +  R+     T+  +  S    + PL   AP S
Sbjct: 406 PLALSSLQATTSLGSPTLQATHSFLT-MSPRQTQASLTSPSRPASTPPDSPPL--QAPLS 462

Query: 616 GPSVP 620
            P+ P
Sbjct: 463 LPASP 467



 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 82/304 (26%), Positives = 107/304 (35%), Gaps = 62/304 (20%)

Query: 371 QKQHKEESHSDGTSTASSQQQAPPQSVPPSQ--IQAP-PMPGPPPLGPPPAPPLRPPGPP 427
           Q  H   + S   + AS    + P S PP    +QAP  +P  PPL    +P + P   P
Sbjct: 424 QATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSP 483

Query: 428 TGL-------------PPGP------PPG------APPFLRPPGMPGLRGPLPRLLPPGP 462
             +             P  P      PP       APP L+ P       PL  L    P
Sbjct: 484 LTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAP 543

Query: 463 PPGRPPGPPPGPP----PGLPPGPPPRGPPPRL---PPPAPPGI--PPPR--PGMMRPPL 511
           PP +    P   P    P  P   P + PP  L   PP  P  I  PPP+  P +  PPL
Sbjct: 544 PPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPL 603

Query: 512 ----VPPLGP-------APPGL-FPPAPLPNPGVLSAPPNLIQRPKADDTSAATIE-KKA 558
                PPL P       APP L  PP   P     S P + +  P     +A  +   +A
Sbjct: 604 QGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQA 663

Query: 559 TATISAKPQITNPKAEITRFVPTALRVRRENKGATAAPQRKSEDDSAVPLAKAAPKSGPS 618
             +    P +  P      F P A          +A P  ++    A P  +  P    S
Sbjct: 664 PFSPPPSPPVQAP------FSPPA----SPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 713

Query: 619 VPVS 622
            P+S
Sbjct: 714 PPMS 717



 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 58/188 (30%), Positives = 66/188 (35%), Gaps = 37/188 (19%)

Query: 384 STASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRP----------PGPPT----- 428
           S ++S   +P  + PP   QAPP+   P L  PP+PP  P          PGP T     
Sbjct: 814 SPSASLPMSPLATPPP---QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP 870

Query: 429 ----GLPPGPPPGAPPFLRPPGM---PGLRGPLP---------RLLPPGPPPGRPPGPPP 472
                L PGPPP  PP   P      P L G            R    GP  G    PPP
Sbjct: 871 RLTLALAPGPPP--PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP 928

Query: 473 GPP-PGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNP 531
                   P    RGP P L     PG P P P    P     L        P +  P P
Sbjct: 929 DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAP 988

Query: 532 GVLSAPPN 539
           G L   P+
Sbjct: 989 GALDPGPS 996



 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 66/242 (27%), Positives = 79/242 (32%), Gaps = 45/242 (18%)

Query: 418 APPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLP----------RLLPPGPP---P 464
           AP L  P PP G P  PPP  P  LR  G  G  G  P            +P   P   P
Sbjct: 21  APGLLTPRPP-GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGP 79

Query: 465 GRPPGPPPGPPPGLPP--GPPPRGPPPRLPPPAPPGIPPPRPGMMRP-PL---------- 511
            R  G     P   PP  G   R PP +   P P   P    G  RP PL          
Sbjct: 80  TRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 139

Query: 512 ----------VPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSA-----ATIEK 556
                      P       G       P PG  S  P + +R +A  T       A   +
Sbjct: 140 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPS--PAMARRSRAAGTEVGLPRPAPSAR 197

Query: 557 KATATISAKPQITNPKAEITRFVPTALRVRRENKGATAAPQRKSEDDSAVPLAKAAPKSG 616
               T   +  +++     T     A R R    G    P  +S   SA PL+  A +SG
Sbjct: 198 PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA-RSG 256

Query: 617 PS 618
           PS
Sbjct: 257 PS 258



 Score = 35.0 bits (79), Expect = 0.21
 Identities = 34/129 (26%), Positives = 48/129 (37%), Gaps = 15/129 (11%)

Query: 140 PLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKP 199
           P P  P A +   +Q +P P A  P     + +   P   ++  P     V   P  + P
Sbjct: 784 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 843

Query: 200 PGPPPG---------PPPPQVVQMYGRKVGFAL----DLPPRRRDEDMLYSPELAQRGHD 246
           P PP           P P     + G ++  AL      PP R     L  P+LA  GH 
Sbjct: 844 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA--GHS 901

Query: 247 DDVSSTSED 255
              +ST E+
Sbjct: 902 SSATSTPEE 910



 Score = 35.0 bits (79), Expect = 0.21
 Identities = 36/127 (28%), Positives = 42/127 (33%), Gaps = 11/127 (8%)

Query: 383  TSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGL--PPGPPPGAPP 440
            ++T++ ++     S P     A P P        PA   R P PP      PG P   PP
Sbjct: 903  SATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPP 962

Query: 441  FLRPPGMPGL------RGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPP 494
               P    GL       GP      PG      PGP PG   G        G   R P  
Sbjct: 963  ATGPGSADGLCTIYETEGPESATPAPG---ALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 1019

Query: 495  APPGIPP 501
            A  G  P
Sbjct: 1020 ARLGELP 1026



 Score = 33.9 bits (76), Expect = 0.47
 Identities = 32/106 (30%), Positives = 39/106 (36%), Gaps = 5/106 (4%)

Query: 364  SEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRP 423
            S A    ++    +S  +G + AS    A   +  P+     P P     G P AP   P
Sbjct: 902  SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP--LP 959

Query: 424  PGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPG 469
              P TG  PG   G        G P    P P  L PGP PG   G
Sbjct: 960  WPPATG--PGSADGLCTIYETEG-PESATPAPGALDPGPSPGTSGG 1002



 Score = 31.6 bits (70), Expect = 2.4
 Identities = 23/78 (29%), Positives = 29/78 (37%), Gaps = 7/78 (8%)

Query: 140 PLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKP 199
           P P  P+A +  L+Q    P   PP     +    PP    +  P         PP + P
Sbjct: 648 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 707

Query: 200 PGPPPGP-------PPPQ 210
           P PP  P       PPPQ
Sbjct: 708 PSPPASPPMSPSATPPPQ 725



 Score = 31.6 bits (70), Expect = 2.4
 Identities = 21/64 (32%), Positives = 26/64 (40%), Gaps = 1/64 (1%)

Query: 145 PHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPP 204
           P AP  +    + +P + P S     SA  PP R   +L      VP  PP   P  P  
Sbjct: 724 PQAPPPLAAPPLQVPPSPPASPPMSPSAT-PPPRVPPLLAAPPLQVPPSPPASLPMSPLA 782

Query: 205 GPPP 208
            PPP
Sbjct: 783 KPPP 786



 Score = 30.4 bits (67), Expect = 5.2
 Identities = 25/86 (29%), Positives = 32/86 (37%), Gaps = 18/86 (20%)

Query: 140 PLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTR--AVSILPLLGHGVP------ 191
           P  + P  P+   +Q  P P   PP     + A  PP    A++  PL G   P      
Sbjct: 556 PHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLA 615

Query: 192 ----------RLPPGRKPPGPPPGPP 207
                      LPP + PP PP  PP
Sbjct: 616 TPPPQAPPXLALPPLQAPPSPPASPP 641



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 22/59 (37%), Positives = 25/59 (42%), Gaps = 5/59 (8%)

Query: 153 IQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPPPQV 211
           +Q  P P A PP     T    PP +A   L      VP  PP   PP  P   PPP+V
Sbjct: 704 LQVPPSPPASPPMSPSAT----PPPQAPPPLAAPPLQVPPSPPA-SPPMSPSATPPPRV 757


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score =  106 bits (264), Expect = 8e-23
 Identities = 85/231 (36%), Positives = 96/231 (41%), Gaps = 55/231 (23%)

Query: 363 DSEAEKQSQKQHKEESHSDGTSTASSQQQ----APPQSVPPSQIQAPPMPGPPPLGPPPA 418
           DS+ E+      +  +  +  S A    Q    APP    P+ + +    G PP G PP 
Sbjct: 181 DSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPP 240

Query: 419 PPLRPPGPPTG-LPPGPPPGAPPFLRPPGMPGLRGPL---------------PRLLPPG- 461
               PP PP G LPPG PP  PP   PPG  G   P                P   PPG 
Sbjct: 241 GSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGG 300

Query: 462 -PPPGR-------------------PPG----PPPGPPPGLP-PGPPPRGPPPRLPP-PA 495
            P PG                    PPG    PPP PPPG+P PGPPP G PPR PP  +
Sbjct: 301 MPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGS 360

Query: 496 PPGIPPPRP--GMM-RPPLVPPLGPAPPGLFPP-----APLPNPGVLSAPP 538
           P G P P P  GM   PPL+PP G   P   PP      PLP P     PP
Sbjct: 361 PMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPP 411



 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 71/183 (38%), Positives = 77/183 (42%), Gaps = 54/183 (29%)

Query: 393 PPQSVPPS---QIQAPPMP------GPPPLGPP-------------PAPPLRPPGP---- 426
           PP ++PP     +  PPMP      GPP  G P             P PP   P P    
Sbjct: 249 PPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQ 308

Query: 427 -------PTGL--PPGPPPGA---PPFLRPPGMPGLRGPLPRLLPPGPPP-GRPP-GPPP 472
                  P GL  P   PPG+   PP   PPGMP           PGPPP G PP GPP 
Sbjct: 309 MQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMP----------HPGPPPMGMPPRGPPF 358

Query: 473 GPPPGLPPGPPP---RGPPPRLPPPAPPGIPPPRP-GMMRPPLVPPLGPAPPGLFPPAPL 528
           G P G P   PP   RGPPP +PP    G P P P G  R PL PP     P + P  PL
Sbjct: 359 GSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPL 418

Query: 529 PNP 531
             P
Sbjct: 419 RGP 421



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 57/128 (44%), Positives = 64/128 (50%), Gaps = 17/128 (13%)

Query: 393 PPQSVPP---SQIQ----APPMPGPPPLGPPPAPPLRPPGPPTGLP-PGPPP-GAPPFLR 443
           PP  +P    SQ+Q     P   G P  GPP +    PP PP G+P PGPPP G PP   
Sbjct: 297 PPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGP 356

Query: 444 PPGMP-GLRGPLPRLLPPGPPPGRPP----GPPPGPPPGLPPGP--PPRGPP-PRLPPPA 495
           P G P G  GP+P     GPPP  PP    GPP  PP G   GP  PPR  P P +PP  
Sbjct: 357 PFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRG 416

Query: 496 PPGIPPPR 503
           P   P P+
Sbjct: 417 PLRGPLPQ 424



 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 53/117 (45%), Positives = 55/117 (47%), Gaps = 27/117 (23%)

Query: 406 PMPGPPPLG--PPPAPP--LRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPG 461
           P  GPP  G  PPP PP  +  PGPP   P G PP  PPF  P G PG          P 
Sbjct: 322 PHAGPPGSGGQPPPRPPPGMPHPGPP---PMGMPPRGPPFGSPMGHPG----------PM 368

Query: 462 PPPGRPPGPPPGPPPGLP--PGPPP----RGPPPRLPPPAPPGIPP-PRPGMMRPPL 511
           PP G    PP  PP G    P PPP    RGP   LPPP P   PP P  G +R PL
Sbjct: 369 PPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGP---LPPPRPTPRPPVPPRGPLRGPL 422



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 29/69 (42%), Positives = 33/69 (47%), Gaps = 9/69 (13%)

Query: 474 PPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGL---FPPAPLPN 530
           PPP   P P        LPPP   G+PP  PG   PP VPP G  PPG+    PP P+P 
Sbjct: 215 PPPPSAPNPVVSSLGSGLPPP---GMPP--PGSFPPP-VPPPGALPPGIPPAMPPPPMPP 268

Query: 531 PGVLSAPPN 539
                 PP+
Sbjct: 269 GAAGHGPPS 277



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 25/66 (37%), Positives = 28/66 (42%), Gaps = 15/66 (22%)

Query: 391 QAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGL 450
           + PP  +PP     PP P P      P PP R    PT  PP PP G            L
Sbjct: 374 RGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPR----PTPRPPVPPRGP-----------L 418

Query: 451 RGPLPR 456
           RGPLP+
Sbjct: 419 RGPLPQ 424



 Score = 37.0 bits (84), Expect = 0.056
 Identities = 26/71 (36%), Positives = 32/71 (45%), Gaps = 9/71 (12%)

Query: 147 APSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPG----- 201
           A   +L    PL  A  P  L    A  PP+    ++  LG G+P  PPG  PPG     
Sbjct: 190 AAERLLAAQNPLSQADRPHQLF-ADAPPPPSAPNPVVSSLGSGLP--PPGMPPPGSFPPP 246

Query: 202 -PPPGPPPPQV 211
            PPPG  PP +
Sbjct: 247 VPPPGALPPGI 257



 Score = 36.6 bits (83), Expect = 0.073
 Identities = 28/103 (27%), Positives = 39/103 (37%), Gaps = 9/103 (8%)

Query: 108 RKLEVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDIPLPGAQPPSIL 167
           R + V Y  K+    +   +           +   D PH     L  D P P + P  ++
Sbjct: 170 RPITVSYAFKKDSKGERHGSAAERLLAAQNPLSQADRPHQ----LFADAPPPPSAPNPVV 225

Query: 168 KKTSAYGPPTRAVSILPLLGHGVPRLPP-GRKPPGPPPGPPPP 209
               +  PP      +P  G   P +PP G  PPG PP  PPP
Sbjct: 226 SSLGSGLPPPG----MPPPGSFPPPVPPPGALPPGIPPAMPPP 264



 Score = 34.7 bits (78), Expect = 0.28
 Identities = 21/66 (31%), Positives = 27/66 (40%), Gaps = 12/66 (18%)

Query: 140 PLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKP 199
           P P  P+   + L   +P PG  PP       ++ PP      LP      P +PP   P
Sbjct: 216 PPPSAPNPVVSSLGSGLPPPGMPPPG------SFPPPVPPPGALP------PGIPPAMPP 263

Query: 200 PGPPPG 205
           P  PPG
Sbjct: 264 PPMPPG 269



 Score = 33.1 bits (74), Expect = 0.81
 Identities = 17/41 (41%), Positives = 21/41 (51%), Gaps = 1/41 (2%)

Query: 187 GHGVPRLPPGRKPPGPPPGPPPPQVVQMYGRKVGFALDLPP 227
           G   PR PPG   PGPPP   PP+    +G  +G    +PP
Sbjct: 331 GQPPPRPPPGMPHPGPPPMGMPPR-GPPFGSPMGHPGPMPP 370



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 26/85 (30%), Positives = 32/85 (37%), Gaps = 16/85 (18%)

Query: 139 IPLPDMPHAPSNILIQDIPLPGAQPPSILKK---------TSAYGPPTRAVSILPLLGHG 189
           +P P MP  P       +P PGA PP I             + +GPP+         G G
Sbjct: 232 LPPPGMP--PPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTP-----GAG 284

Query: 190 VPRLPPGRKPPGPPPGPPPPQVVQM 214
            P        P PP G P P + QM
Sbjct: 285 HPGHGHSHPHPFPPGGMPHPGMSQM 309


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score =  105 bits (263), Expect = 1e-22
 Identities = 77/229 (33%), Positives = 91/229 (39%), Gaps = 41/229 (17%)

Query: 350 EEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMP- 408
           +  +ED  +++S    A        +  +   G      + Q PP     ++ Q PP P 
Sbjct: 17  QNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQ-GGNKPQGPPPPG 75

Query: 409 ---GPPPLGPPPAPPLRPPGPPTGLP---------PGPPPGAPPFLRPPGMPGLRGPLPR 456
              GPPP G     P  PPG P G P         P PPPG P    P G    +GP P 
Sbjct: 76  KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPP 135

Query: 457 LLPPGP------------PPGRPPGPP---------PGPPPGLPPGPPPRG--PPPRLPP 493
             P GP            PPG+P GPP         P PPPG P GPPP+G   P   PP
Sbjct: 136 GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPP 195

Query: 494 PAPPGIPPPRPGMMRPPLVPPLGPAPP----GLFPPAPLPNPGVLSAPP 538
           P  P  PPP+    R    PP  P  P    G  P  P P PG    PP
Sbjct: 196 PGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 244



 Score =  103 bits (258), Expect = 4e-22
 Identities = 83/217 (38%), Positives = 96/217 (44%), Gaps = 49/217 (22%)

Query: 364 SEAEKQSQKQHKEESHS------DGTST-ASSQQQAPPQSVPPSQIQAPPMPG------P 410
           S A+  ++   +EES S       G S    ++ Q PP   PP + Q PP  G      P
Sbjct: 14  SSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPP--PPGKPQGPPPQGGNKPQGP 71

Query: 411 PPLGPPPAPP-----LRPPGPPTGLPPGPPP-------GAPPFLRPPGMPGLRGPLPR-- 456
           PP G P  PP      R P  P G P GPPP       G PP   PPG P  +GP P+  
Sbjct: 72  PPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPP---PPGKP--QGPPPQGG 126

Query: 457 LLPPGPPP-GRPPGPPPG--------PPPGLPPGPPPRG---PPPRLPPPAPPGIPPPRP 504
             P GPPP G+P GPPP          PPG P GPPP+G   P    PPP  P  PPP+ 
Sbjct: 127 NRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 186

Query: 505 GMM---RPPLVPPLGPAPPGLFPPAPLPNPGVLSAPP 538
           G      PP   P GP P G    +    PG    PP
Sbjct: 187 GKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPP 223



 Score =  103 bits (256), Expect = 6e-22
 Identities = 79/193 (40%), Positives = 87/193 (45%), Gaps = 50/193 (25%)

Query: 388 SQQQAPPQSVPPSQIQAPPMPG------PPPLGPPPAPP-----LRPPGPPTGLPPGPPP 436
           +Q Q PP   PP + Q PP  G      PPP G P  PP      R P  P G P GPPP
Sbjct: 106 NQPQGPPP--PPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPP 163

Query: 437 -------GAPPFLRPPGMPGLRGPLPR--LLPPGPPP-GRPPGPPPG--------PPPGL 478
                  G PP   PPG P  +GP P+    P GPPP G+P GPPP          PPG 
Sbjct: 164 QGGNQPQGPPP---PPGKP--QGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGK 218

Query: 479 PPGPPPRG---PPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLS 535
           P GPPP+G   P    PPP  P  PPP+ G        P GP PPG  P  P    G  S
Sbjct: 219 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN------KPQGPPPPGK-PQGPPAQGGSKS 271

Query: 536 ----APPNLIQRP 544
               +PP   Q P
Sbjct: 272 QSARSPPGKPQGP 284



 Score = 99.8 bits (247), Expect = 7e-21
 Identities = 71/185 (38%), Positives = 83/185 (44%), Gaps = 25/185 (13%)

Query: 366 AEKQSQKQHKEESHSDGTSTASSQQQAP-PQSVPPSQIQAPPMPGPPPLGPPPAPPLRPP 424
           A   +Q  +++ S  +  S  +   Q P PQ    ++ Q PP P   P GPPP    +P 
Sbjct: 12  ALSSAQNLNEDVSQEESPSLIAGNPQGPSPQG--GNKPQGPPPPPGKPQGPPPQGGNKPQ 69

Query: 425 GPPT-GLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPP---GRPPGPPPGPPPGLPP 480
           GPP  G P GPPP       P   PG         P GPPP    +P GPPP  PPG P 
Sbjct: 70  GPPPPGKPQGPPPQGDKSRSPRSPPGK--------PQGPPPQGGNQPQGPPP--PPGKPQ 119

Query: 481 GPPPRGPPPRLPPPAPPGI---PPPRPGMMRPPLVPPLGPAPP----GLFPPAPLPNPGV 533
           GPPP+G      PP PPG    PPP+    R P  PP  P  P    G  P  P P PG 
Sbjct: 120 GPPPQGGNRPQGPP-PPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK 178

Query: 534 LSAPP 538
              PP
Sbjct: 179 PQGPP 183



 Score = 93.6 bits (231), Expect = 5e-19
 Identities = 75/185 (40%), Positives = 82/185 (44%), Gaps = 52/185 (28%)

Query: 394 PQSVPP---SQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPP-------FLR 443
           PQ  PP   +Q Q PP P   P GPPP    +P GPP   PPG P G PP          
Sbjct: 158 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPP---PPGKPQGPPPQGDKSRSSQS 214

Query: 444 PPGMPGLRGPLPR--------LLPPGPPPGRPP-------GPPPGPPPGLPPGPPPRG-- 486
           PPG P  +GP P+          PPG P G PP       GPP   PPG P GPP +G  
Sbjct: 215 PPGKP--QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP---PPGKPQGPPAQGGS 269

Query: 487 -------PP--PRLPPPA----PPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGV 533
                  PP  P+ PP      P G PPP  G  + P  PP G  P G  PP P P  G 
Sbjct: 270 KSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAG-QPQG--PPRP-PQGGR 325

Query: 534 LSAPP 538
            S PP
Sbjct: 326 PSRPP 330



 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 57/146 (39%), Positives = 62/146 (42%), Gaps = 28/146 (19%)

Query: 391 QAPPQSVPPSQIQAPPMPG--------PP--PLGPPPA---PPLRPPGPPTGLPPGPPP- 436
           Q PP   PP + Q PP  G        PP  P GPPP     P  PP PP G P GPPP 
Sbjct: 191 QGPP---PPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPP-PPPGKPQGPPPQ 246

Query: 437 ------GAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPR 490
                 G PP  +P G P   G   +      PPG+P GPP          PPP G  P+
Sbjct: 247 GGNKPQGPPPPGKPQGPPAQGG--SKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQ 304

Query: 491 LPPPAPPGIP--PPRPGMMRPPLVPP 514
            P   P G P  PPRP     P  PP
Sbjct: 305 QPQAPPAGQPQGPPRPPQGGRPSRPP 330



 Score = 73.9 bits (180), Expect = 4e-13
 Identities = 49/124 (39%), Positives = 55/124 (44%), Gaps = 16/124 (12%)

Query: 384 STASSQQQAPPQSVPP---SQIQAPPMPGPPPLGPPPAPPLRPPGPPT-GLPPGPP---- 435
           S +S      PQ  PP   +Q Q PP P   P GPPP    +P GPP  G P GPP    
Sbjct: 209 SRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGG 268

Query: 436 ----PGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGP--PPRGPPP 489
                   P  +P G P   G  P+   P PP G  P  P  PP G P GP  PP+G  P
Sbjct: 269 SKSQSARSPPGKPQGPPQQEGNNPQ--GPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRP 326

Query: 490 RLPP 493
             PP
Sbjct: 327 SRPP 330



 Score = 70.5 bits (171), Expect = 5e-12
 Identities = 58/167 (34%), Positives = 64/167 (38%), Gaps = 56/167 (33%)

Query: 388 SQQQAPPQSVPPSQIQAPPMPG------PPPLGPPPAPPLR---------PPGPPTGLPP 432
           +Q Q PP   PP + Q PP  G      PPP G P  PP +         PPG P G PP
Sbjct: 167 NQPQGPPP--PPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPP 224

Query: 433 G---------PPPGAPPFLRPPGMPGLRGPLPRLLPPGPP-------------PGRPPGP 470
                     PPPG P    P G    +GP P   P GPP             PG+P GP
Sbjct: 225 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGP 284

Query: 471 P--------------PGPP--PGLPPGPPPRGPPPRLPPPAPPGIPP 501
           P               G P  P  PP   P+G PPR P    P  PP
Sbjct: 285 PQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQG-PPRPPQGGRPSRPP 330



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 30/69 (43%), Positives = 33/69 (47%), Gaps = 6/69 (8%)

Query: 380 SDGTSTASSQQQAP--PQSVPPSQIQAPPMPGPPPLGPPPAPPLRPP-GPPTGLPPGPPP 436
           + G S + S +  P  PQ  PP Q    P   PPP G  P  P  PP G P G PP PP 
Sbjct: 265 AQGGSKSQSARSPPGKPQG-PPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQG-PPRPPQ 322

Query: 437 GAPPFLRPP 445
           G  P  RPP
Sbjct: 323 GGRP-SRPP 330



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 27/80 (33%), Positives = 31/80 (38%), Gaps = 16/80 (20%)

Query: 140 PLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRA-VSILPLLGHGVPRLPP--- 195
           P P  P  P        P  G +P          GPP +   S  P    G P+ PP   
Sbjct: 52  PPPGKPQGPP-------PQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG 104

Query: 196 GRKPPGPPPGP-----PPPQ 210
           G +P GPPP P     PPPQ
Sbjct: 105 GNQPQGPPPPPGKPQGPPPQ 124



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 27/80 (33%), Positives = 31/80 (38%), Gaps = 16/80 (20%)

Query: 140 PLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRA-VSILPLLGHGVPRLPP--- 195
           P P  P  P        P  G +P          GPP +   S  P    G P+ PP   
Sbjct: 113 PPPGKPQGPP-------PQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG 165

Query: 196 GRKPPGPPPGP-----PPPQ 210
           G +P GPPP P     PPPQ
Sbjct: 166 GNQPQGPPPPPGKPQGPPPQ 185



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 22/60 (36%), Positives = 25/60 (41%), Gaps = 20/60 (33%)

Query: 159 PGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPP---GRKPPGPPPGP-----PPPQ 210
           P   PP   K  S+  PP            G P+ PP   G +P GPPP P     PPPQ
Sbjct: 199 PQGPPPQGDKSRSSQSPP------------GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 246



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 22/67 (32%), Positives = 25/67 (37%), Gaps = 17/67 (25%)

Query: 159 PGAQPPSILKKTSAYGPPTRAVSILPLLGH---------GVPRLPP--------GRKPPG 201
           P   PP   K  S   PP +     P  G+         G P+ PP        G  PPG
Sbjct: 77  PQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPG 136

Query: 202 PPPGPPP 208
            P GPPP
Sbjct: 137 KPQGPPP 143



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 22/67 (32%), Positives = 25/67 (37%), Gaps = 17/67 (25%)

Query: 159 PGAQPPSILKKTSAYGPPTRAVSILPLLGH---------GVPRLPP--------GRKPPG 201
           P   PP   K  S   PP +     P  G+         G P+ PP        G  PPG
Sbjct: 138 PQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPG 197

Query: 202 PPPGPPP 208
            P GPPP
Sbjct: 198 KPQGPPP 204


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score =  103 bits (257), Expect = 5e-22
 Identities = 108/418 (25%), Positives = 159/418 (38%), Gaps = 79/418 (18%)

Query: 137 ESIPLPDMPHA--PSNILIQDIPLPGAQPPSILKKTSAYGPPT-----RAVSILPLLGHG 189
           ++ P P    A  P    +   P P  +P +    T+A+G        RA +  PL    
Sbjct: 386 QATPAPGFKSAFSPYQTPVAHFPPPPEEPTA----TAAFGARDSGEFRRAPAPPPL---- 437

Query: 190 VPRLPPGRKPPGPPPGPPPPQVVQM-YGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDD 248
            P  P  ++ PG PPGPPPP    M  G +  F              +SPE         
Sbjct: 438 PPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFG-------------WSPEPCDSPGTPT 484

Query: 249 VSSTSEDDGYPEDMDQDKHDDSTDDSDTDKSD-GESDGDEFVHRDNGERDNNEEKKSGLS 307
           + S+      P D    + +    +  T      E D D  +  +     ++  + S L+
Sbjct: 485 LESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLA 544

Query: 308 VRFADM--------PGKSRKKKKNMKELTPL--------QAMMLRMAGQEIPEEGREVEE 351
               +         P  SR     +++++P         + + L +  +  PE G     
Sbjct: 545 PFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPA 604

Query: 352 FSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPP 411
                  + + D   ++    +  +E    G  ++    +     +P + I +   P P 
Sbjct: 605 GLLSQTAEVALDLVGDRTPTSEKMDE----GQQSSGEDMEISDDEMPSAPITSADCPKPM 660

Query: 412 PLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRP--PG 469
            + P  A    P      LP  PPPG PP   PP             PP PPP +P  P 
Sbjct: 661 VVTPGAAAVAAPSVLAPTLPLPPPPGFPPL--PP-------------PPPPPPPQPGFPM 705

Query: 470 PPPGPPPGLPPGPPPRGPPPRLPP---PAPPGIPPPRPGMMRPPLVPPLGPAPPGLFP 524
           PPP PPP  PP PPP  P   +PP   PAPPG+PP       PP++PPL P PPGLFP
Sbjct: 706 PPPLPPP--PPPPPPAHPAVTVPPPPLPAPPGVPP-------PPILPPLPPFPPGLFP 754



 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 111/450 (24%), Positives = 153/450 (34%), Gaps = 104/450 (23%)

Query: 228  RRRDEDMLYSP-ELAQR--------------------GHDDDVSSTSEDDGYPEDMDQDK 266
            R RD DM  +P ELA+R                    G +D+  S SE+    E+ ++ +
Sbjct: 996  RERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQESTEEEEEAE 1055

Query: 267  HDDSTDDSDTDKSDGESDGDEFVHRDNGERDNNEEKKSGLSVRFADMPGKSRKKKKNMKE 326
             ++  +D D D SD          RD  E D+ +   S  S           +K +   +
Sbjct: 1056 EEEEEEDDDDDDSDD---------RDESENDDEDTALSEAS-----------EKDEGDSD 1095

Query: 327  LTPLQAMMLRMAGQEIPEEGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTA 386
                 +++   A      E  E  EF    +   S   + E+   ++ +EE   +     
Sbjct: 1096 EEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAE 1155

Query: 387  SSQQQAPPQSVPPSQIQAPPMPGPPPLGP------------PPAPPLRPP---GPPTGLP 431
             S   A P+       +A   PG P +                AP  RP     PP  LP
Sbjct: 1156 ESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPP--LP 1213

Query: 432  PGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPP----GRPPGPP-----------PGPP- 475
             G    A     PP  PGL      LL P PP      RPP  P           P PP 
Sbjct: 1214 VGVEEPADS-REPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPM 1272

Query: 476  ----PGLPPGPPPRGPPPRLPPPAP-------PGIPPPRPGMMRPPLVPPL--------- 515
                P  PP PPPR P P  PPP P       P +PP       PP  P L         
Sbjct: 1273 MLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQS 1332

Query: 516  ---GPAPPGLFPPAPLPNPGVLSAPPNLIQRP-----KADDTSAATIEKKATATISAKPQ 567
                PA PG  PP    + G+  + P +   P      +   S+  + +      S  P 
Sbjct: 1333 TETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPT 1392

Query: 568  ITNPKAEITRFV-PTALRVRRENKGATAAP 596
             + P   +   V P     R E  G  A+P
Sbjct: 1393 FSEPSGPLLLPVCPLPTGRRDERSGPLASP 1422



 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 96/372 (25%), Positives = 138/372 (37%), Gaps = 59/372 (15%)

Query: 217  RKVGFALDLPPRRRDEDMLYSPELAQRGHDDDVSSTSEDDGYPEDMDQDKHDDS-TDDSD 275
            R+    L+L     +++     E  +   +++ +   E++   +D D D  D+S  DD D
Sbjct: 1021 RRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDED 1080

Query: 276  T------DKSDGESDGDEFVHRDNGERDNNEEKKSGLSVRFADMPGKSRKKKKNMKELTP 329
            T      +K +G+SD +E V     + +     +S  S  F      S    ++ +E   
Sbjct: 1081 TALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEE--- 1137

Query: 330  LQAMMLRMAGQEIPEEGREVEE--FSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTAS 387
               ++ R   +E  EE    EE   S   ++ + D  EA         +    +      
Sbjct: 1138 ---VVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIE 1194

Query: 388  SQQQAPPQSVPPSQIQAPPMP----GPPPLGPPPAPP--------LRPPGPPT----GLP 431
            ++  AP +   PS +  PP+P     P     PP  P        L  P PP       P
Sbjct: 1195 TEAVAPEER--PSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARP 1252

Query: 432  PGPPPGAPPF-LRPPGMPGLRGPLPRLLPPGPP--PGRPPGPPPGPP------PGLPPGP 482
            P  P  AP   L     P +  PLP L PP PP  P RPP PPP P       P +PP P
Sbjct: 1253 PLSPERAPEHDLEVEPEPPMMLPLP-LQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEP 1311

Query: 483  PPRGPPPRLP---------------PPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFP-PA 526
                 PP  P               P  P G PP   G     L  P  P  P  +P P+
Sbjct: 1312 LAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPS 1371

Query: 527  PLPNPGVLSAPP 538
            P  + G L   P
Sbjct: 1372 PSLSSGGLPRTP 1383



 Score = 63.5 bits (153), Expect = 6e-10
 Identities = 64/185 (34%), Positives = 70/185 (37%), Gaps = 58/185 (31%)

Query: 400  SQIQAP-PMPG--PPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPR 456
            +Q +AP P+P   P PL   P P  R PG P   PP       P +RPP    L   L  
Sbjct: 1449 AQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGREL-- 1506

Query: 457  LLPPGPPPGRPPGPP----------------PGPPPGLPPGPPPRGPPP-----RLP--- 492
            LL PG P   P  P                 P PPP LPP PPP  PPP     +LP   
Sbjct: 1507 LLLPGQPQ-TPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKE 1565

Query: 493  ----------PPAPPG----------IPPPRPGMMRPP------LVPPLGPAPPGLFPPA 526
                      PP P G          +   R    RPP      LVPP G   P L PP 
Sbjct: 1566 LDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAG--SPELSPPQ 1623

Query: 527  PLPNP 531
            PL  P
Sbjct: 1624 PLFRP 1628



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 61/223 (27%), Positives = 70/223 (31%), Gaps = 56/223 (25%)

Query: 377 ESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPP---- 432
           E   +G+  +SS  Q  P + P      P   GP P    P+        PT LP     
Sbjct: 525 ELQMEGSPISSSSSQLSPLA-PFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDED 583

Query: 433 -----GPPPGAPPFLRPPGMPGLRGPLPRL------------------------------ 457
                G  P  PP   PP   GL      +                              
Sbjct: 584 EELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISD 643

Query: 458 --LPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGI---------PPPRPGM 506
             +P  P        P    PG      P    P LP P PPG          PPP+PG 
Sbjct: 644 DEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGF 703

Query: 507 -MRPPLVPPLGPAPPG----LFPPAPLPNPGVLSAPPNLIQRP 544
            M PPL PP  P PP       PP PLP P  +  PP L   P
Sbjct: 704 PMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLP 746



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 35/109 (32%), Positives = 40/109 (36%), Gaps = 9/109 (8%)

Query: 378  SHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAP--PLRPPGPPTGLPPGPP 435
            +H   T T   +    P   PP   Q PP P PPP+ P   P   L    P   +PPGP 
Sbjct: 1521 THDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPR 1580

Query: 436  PGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPG--PPPGPPPGLPPGP 482
                       +   RGP  R     PP  R     PP G P   PP P
Sbjct: 1581 GRDEVTEEYMELAKSRGPWRR-----PPKKRHEDLVPPAGSPELSPPQP 1624



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 57/187 (30%), Positives = 73/187 (39%), Gaps = 40/187 (21%)

Query: 393 PPQSVPPSQI---QAPPMPGPPPLGPP------------PAPPLRPPGPPTGLPPGPPPG 437
           PP   PP Q      PP+P PPP  PP            PAPP  PP      PP  PP 
Sbjct: 692 PPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPP------PPILPP- 744

Query: 438 APPFLRPPGM-PGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAP 496
            PPF  PPG+ P ++  +  +L  G   G  P         L      +G  P  PP   
Sbjct: 745 LPPF--PPGLFPVMQVDMSHVL--GGQWGGMPMSFQMQTQVLSRLMTGQGACP-YPPFMA 799

Query: 497 PGIPPPRPGMMRPPLVPPLGP-----APPGL---FPPAPLPNPGVLSAPPNLIQRPKADD 548
                   G+    L P  GP     + PG    +PP P  +P V   PP  +  P+ +D
Sbjct: 800 AAAAAASAGLQFVNLPPYRGPFSLSNSGPGRGQHWPPLPKFDPSV--PPPGYM--PRQED 855

Query: 549 TSAATIE 555
              AT++
Sbjct: 856 PHKATVD 862



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 42/158 (26%), Positives = 51/158 (32%), Gaps = 30/158 (18%)

Query: 414 GPPPAPPLR--PPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPP 471
           G    PP +  P    T     PP  A P    PG      P    +   PPP   P   
Sbjct: 361 GGSSGPPFKAQPQDSATFAHTPPPAQATP---APGFKSAFSPYQTPVAHFPPPPEEPTAT 417

Query: 472 --------------PGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGP 517
                         P PPP      PP  P  +  P  PPG PPP    M       LG 
Sbjct: 418 AAFGARDSGEFRRAPAPPP-----LPPAEPLAKEKPGTPPGPPPPDTNSME------LGG 466

Query: 518 APPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSAATIE 555
            P   + P P  +PG  +   +     K  D+  + IE
Sbjct: 467 RPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIE 504



 Score = 33.1 bits (74), Expect = 0.81
 Identities = 23/61 (37%), Positives = 29/61 (47%), Gaps = 8/61 (13%)

Query: 189  GVPRLPPGRKPPGPPPGPPPPQV-------VQMYGRKVGFALDLPPRRRDEDMLYSPELA 241
            G+P  PP   PP PPP PPPP V        ++  +    A+   PR RDE      ELA
Sbjct: 1535 GIPA-PPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELA 1593

Query: 242  Q 242
            +
Sbjct: 1594 K 1594



 Score = 31.2 bits (69), Expect = 3.1
 Identities = 55/220 (25%), Positives = 63/220 (28%), Gaps = 72/220 (32%)

Query: 380 SDGTSTASSQQQAPPQSVPPSQIQAPPMPG---------------PPPLGPPPAPPL--- 421
           S G    +  Q +   +  P   QA P PG               PPP   P A      
Sbjct: 363 SSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGA 422

Query: 422 -------RPPGPPTGLPPGPP-----PGAPPFLRPPGMPGLR---------GPLPRLLPP 460
                  R P PP  LPP  P     PG PP   PP    +           P P   P 
Sbjct: 423 RDSGEFRRAPAPPP-LPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPG 481

Query: 461 GPPPGRPPGPPPGPPPGLP----------------------------PGPPPRGPPPRLP 492
            P     P  P  P   L                              G P      +L 
Sbjct: 482 TPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLS 541

Query: 493 PPAPPGIPPPRPGMMRPPLVPPLGPAPPGL--FPPAPLPN 530
           P AP G    +PG  R P  P   P+  GL    P PLP+
Sbjct: 542 PLAPFG-TNSQPG-FRGPTPPSSRPSSTGLEDISPTPLPD 579


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score =  103 bits (256), Expect = 6e-22
 Identities = 86/271 (31%), Positives = 111/271 (40%), Gaps = 52/271 (19%)

Query: 320 KKKNMKELTPLQAMMLRMAGQEIPEEGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESH 379
           +KK   ELT    + + M   E   E +++++   + D   S+  +   + Q    E S 
Sbjct: 476 EKKLDSELTARHELQVEMKKMESDFE-QKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQ 534

Query: 380 SDGTSTASSQQ-----------QAPPQSVPPSQIQAPPMPGPPPLG--------PPPAP- 419
             G     +++            A   +VPPS     P+P  PPL         PPPAP 
Sbjct: 535 LTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPG 594

Query: 420 --PLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPP- 476
                PP PP   PP P PG      PP +PG       + PP P  G    PPP P P 
Sbjct: 595 DSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTA----ISPPPPLSGDATIPPPPPLPE 650

Query: 477 --GLP-----------PGPPPRGPPPRLPPPAPP-----GIPPPRPGMM----RPPLVPP 514
             G+P           P PPP     R+PPP PP     GIPPP P +      PP  PP
Sbjct: 651 GVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPP 710

Query: 515 LGPAPPGLFPPAPLP-NPGVLSAPPNLIQRP 544
           L P  PG+ PP P P  PG+   PP +   P
Sbjct: 711 L-PGGPGIPPPPPFPGGPGIPPPPPGMGMPP 740



 Score = 99.8 bits (247), Expect = 7e-21
 Identities = 89/239 (37%), Positives = 106/239 (44%), Gaps = 46/239 (19%)

Query: 340 QEIPEEGREVE-EFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVP 398
           Q+I  E +++E E S+   E      E E  ++K+    S +  T   S   +AP    P
Sbjct: 519 QQIATEKQDLEAEVSQLTGEVAKLTKELE-DAKKEMASLSAAAITVPPSVPSRAPVPPAP 577

Query: 399 P------SQIQAPPMPG------PPPLGPPPAPPL-------RPPGPPTGLPPGPPP--- 436
           P      + I  PP PG      PPP  PPP PPL        PP  P G    PPP   
Sbjct: 578 PLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLS 637

Query: 437 GAPPFLRPPGMP-GLRGPLPRLLPPG---PPPGRPPGP---PPGPPP-----GLPPGPPP 484
           G      PP +P G+  P P  LP G   PPP   PG    PP PPP     G+PP PPP
Sbjct: 638 GDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPP 697

Query: 485 RG-----PPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGL-FPPAPLPNPGVLSAP 537
                  PPP  P P  PGIPPP P    P + PP    PPG+  PP P    GV +AP
Sbjct: 698 LPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPP----PPGMGMPPPPPFGFGVPAAP 752



 Score = 90.9 bits (224), Expect = 3e-18
 Identities = 72/179 (40%), Positives = 80/179 (44%), Gaps = 41/179 (22%)

Query: 382 GTSTASSQQQAPPQSVPPSQ----IQAPP-MPG------PPPLGP----PPAPPLRPPG- 425
           G ST       PP   PP      I +PP +PG      PPPL      PP PPL P G 
Sbjct: 594 GDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPL-PEGV 652

Query: 426 ---PPTGLPPG----PPPGAPPFLR----PPGMPGLRGPLPRLLPPGPPP-----GRPPG 469
               P+ LP G    PPP  P   R    PP +PG  G     +PP PPP     G PP 
Sbjct: 653 GIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAG-----IPPPPPPLPGEAGMPPP 707

Query: 470 PPPGP-PPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVP--PLGPAPPGLFPP 525
           PPP P  PG+PP PP  G P   PPP   G+PPP P     P  P  P G  P  L+ P
Sbjct: 708 PPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKP 766



 Score = 72.8 bits (177), Expect = 9e-13
 Identities = 52/129 (40%), Positives = 63/129 (48%), Gaps = 22/129 (17%)

Query: 381 DGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPP---- 436
           +G    S        ++PP     PP+PG   + PPP PPL  PG   G+PP PPP    
Sbjct: 650 EGVGIPSPSSLPGGTAIPPP----PPLPGSARI-PPPPPPL--PGS-AGIPPPPPPLPGE 701

Query: 437 -GAPPFLRPPGMPGLRGPLPRLLPPGPP-PGRPPGPPPGPPPGLPPGPPPRGPPPRLPPP 494
            G PP   PP +PG  G     +PP PP PG P  PPP P  G+PP PPP G      P 
Sbjct: 702 AGMPP--PPPPLPGGPG-----IPPPPPFPGGPGIPPPPPGMGMPP-PPPFGFGVPAAPV 753

Query: 495 APPGIPPPR 503
            P G+ P +
Sbjct: 754 LPFGLTPKK 762



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 45/189 (23%), Positives = 74/189 (39%), Gaps = 32/189 (16%)

Query: 32  KNKKQRMMVRAAVLKMKDPKQIIRDMEKLDEMEFNPVQQPQLNEKVLKDKRKKLRETFER 91
           K +  ++ +   + +M D  ++ +   K  E+E   +         L+ + KK+   FE+
Sbjct: 444 KCRHLQIEIEGLIDQMIDKTKVEKSEAKAAELE-KKLDSELTARHELQVEMKKMESDFEQ 502

Query: 92  ILRLYEKENPDIYKELRKLEVEYEQKRAQLSQYF-----------DAVKNAQHVEVESIP 140
            L+  + E   ++ E +++  E +   A++SQ             DA K    +   +I 
Sbjct: 503 KLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAIT 562

Query: 141 LPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPP 200
           +P  P  PS       P+P A P           P      I P    G    PP   PP
Sbjct: 563 VP--PSVPSRA-----PVPPAPPL----------PGDSGTIIPPPPAPGDSTTPP---PP 602

Query: 201 GPPPGPPPP 209
            PPP PPPP
Sbjct: 603 PPPPPPPPP 611



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 62/240 (25%), Positives = 86/240 (35%), Gaps = 60/240 (25%)

Query: 141 LPDMPHAPSNILIQDIP--LPGAQ----PPSILKKTSAYGPPTRAVSILPLLGHGVPRLP 194
           +P  P  P +  I   P  LPG+     PP  L   +   PP   +      G G+P  P
Sbjct: 666 IPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPG----GPGIPPPP 721

Query: 195 PGRKPPGPPPGPP----PPQVVQMYGRKVGFAL--DLPPRRRDEDMLYSPELAQR--GHD 246
           P    PG PP PP    PP     +G      L   L P++     LY PE+  R     
Sbjct: 722 PFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKK-----LYKPEVQLRRPNWS 776

Query: 247 DDVSSTSEDDGYPEDMDQDKHDDS--------TDDSDTDKSDGESDGDEFVHRDNGERDN 298
             V+     D +   + +D+ +++        T  + T  S  + D           ++ 
Sbjct: 777 KLVAEDLSQDCFWTKVKEDRFENNELFAKLTLTFSAQTKTSKAKKD-----------QEG 825

Query: 299 NEEKKSGLSVRFADMPGKSRKKKKNMKELTPLQAMML-------RMAGQEIPEEGREVEE 351
            EEKKS             +KK K +K L    A  L       RM  QEI     EV E
Sbjct: 826 GEEKKS-----------VQKKKVKELKVLDSKTAQNLSIFLGSFRMPYQEIKNVILEVNE 874



 Score = 30.4 bits (67), Expect = 5.2
 Identities = 31/92 (33%), Positives = 35/92 (38%), Gaps = 23/92 (25%)

Query: 140 PLPDMPHAPSNILIQDIP-LPGA---QPPSILKKTSAYGPPTR--------AVSILPLLG 187
           P P  P  P  + I   P LPG     PP  L   +   PP          + S LP  G
Sbjct: 605 PPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPG-G 663

Query: 188 HGVPRLPP----GRKPPGPPP------GPPPP 209
             +P  PP     R PP PPP       PPPP
Sbjct: 664 TAIPPPPPLPGSARIPPPPPPLPGSAGIPPPP 695


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score =  103 bits (256), Expect = 6e-22
 Identities = 86/271 (31%), Positives = 111/271 (40%), Gaps = 52/271 (19%)

Query: 320 KKKNMKELTPLQAMMLRMAGQEIPEEGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESH 379
           +KK   ELT    + + M   E   E +++++   + D   S+  +   + Q    E S 
Sbjct: 485 EKKLDSELTARHELQVEMKKMESDFE-QKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQ 543

Query: 380 SDGTSTASSQQ-----------QAPPQSVPPSQIQAPPMPGPPPLG--------PPPAP- 419
             G     +++            A   +VPPS     P+P  PPL         PPPAP 
Sbjct: 544 LTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPG 603

Query: 420 --PLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPP- 476
                PP PP   PP P PG      PP +PG       + PP P  G    PPP P P 
Sbjct: 604 DSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTA----ISPPPPLSGDATIPPPPPLPE 659

Query: 477 --GLP-----------PGPPPRGPPPRLPPPAPP-----GIPPPRPGMM----RPPLVPP 514
             G+P           P PPP     R+PPP PP     GIPPP P +      PP  PP
Sbjct: 660 GVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPP 719

Query: 515 LGPAPPGLFPPAPLP-NPGVLSAPPNLIQRP 544
           L P  PG+ PP P P  PG+   PP +   P
Sbjct: 720 L-PGGPGIPPPPPFPGGPGIPPPPPGMGMPP 749



 Score = 99.8 bits (247), Expect = 7e-21
 Identities = 89/239 (37%), Positives = 106/239 (44%), Gaps = 46/239 (19%)

Query: 340 QEIPEEGREVE-EFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVP 398
           Q+I  E +++E E S+   E      E E  ++K+    S +  T   S   +AP    P
Sbjct: 528 QQIATEKQDLEAEVSQLTGEVAKLTKELE-DAKKEMASLSAAAITVPPSVPSRAPVPPAP 586

Query: 399 P------SQIQAPPMPG------PPPLGPPPAPPL-------RPPGPPTGLPPGPPP--- 436
           P      + I  PP PG      PPP  PPP PPL        PP  P G    PPP   
Sbjct: 587 PLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLS 646

Query: 437 GAPPFLRPPGMP-GLRGPLPRLLPPG---PPPGRPPGP---PPGPPP-----GLPPGPPP 484
           G      PP +P G+  P P  LP G   PPP   PG    PP PPP     G+PP PPP
Sbjct: 647 GDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPP 706

Query: 485 RG-----PPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGL-FPPAPLPNPGVLSAP 537
                  PPP  P P  PGIPPP P    P + PP    PPG+  PP P    GV +AP
Sbjct: 707 LPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPP----PPGMGMPPPPPFGFGVPAAP 761



 Score = 90.9 bits (224), Expect = 3e-18
 Identities = 72/179 (40%), Positives = 80/179 (44%), Gaps = 41/179 (22%)

Query: 382 GTSTASSQQQAPPQSVPPSQ----IQAPP-MPG------PPPLGP----PPAPPLRPPG- 425
           G ST       PP   PP      I +PP +PG      PPPL      PP PPL P G 
Sbjct: 603 GDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPL-PEGV 661

Query: 426 ---PPTGLPPG----PPPGAPPFLR----PPGMPGLRGPLPRLLPPGPPP-----GRPPG 469
               P+ LP G    PPP  P   R    PP +PG  G     +PP PPP     G PP 
Sbjct: 662 GIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAG-----IPPPPPPLPGEAGMPPP 716

Query: 470 PPPGP-PPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVP--PLGPAPPGLFPP 525
           PPP P  PG+PP PP  G P   PPP   G+PPP P     P  P  P G  P  L+ P
Sbjct: 717 PPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKP 775



 Score = 72.8 bits (177), Expect = 9e-13
 Identities = 52/129 (40%), Positives = 63/129 (48%), Gaps = 22/129 (17%)

Query: 381 DGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPP---- 436
           +G    S        ++PP     PP+PG   + PPP PPL  PG   G+PP PPP    
Sbjct: 659 EGVGIPSPSSLPGGTAIPPP----PPLPGSARI-PPPPPPL--PGS-AGIPPPPPPLPGE 710

Query: 437 -GAPPFLRPPGMPGLRGPLPRLLPPGPP-PGRPPGPPPGPPPGLPPGPPPRGPPPRLPPP 494
            G PP   PP +PG  G     +PP PP PG P  PPP P  G+PP PPP G      P 
Sbjct: 711 AGMPP--PPPPLPGGPG-----IPPPPPFPGGPGIPPPPPGMGMPP-PPPFGFGVPAAPV 762

Query: 495 APPGIPPPR 503
            P G+ P +
Sbjct: 763 LPFGLTPKK 771



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 45/189 (23%), Positives = 74/189 (39%), Gaps = 32/189 (16%)

Query: 32  KNKKQRMMVRAAVLKMKDPKQIIRDMEKLDEMEFNPVQQPQLNEKVLKDKRKKLRETFER 91
           K +  ++ +   + +M D  ++ +   K  E+E   +         L+ + KK+   FE+
Sbjct: 453 KCRHLQIEIEGLIDQMIDKTKVEKSEAKAAELE-KKLDSELTARHELQVEMKKMESDFEQ 511

Query: 92  ILRLYEKENPDIYKELRKLEVEYEQKRAQLSQYF-----------DAVKNAQHVEVESIP 140
            L+  + E   ++ E +++  E +   A++SQ             DA K    +   +I 
Sbjct: 512 KLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAIT 571

Query: 141 LPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPP 200
           +P  P  PS       P+P A P           P      I P    G    PP   PP
Sbjct: 572 VP--PSVPSRA-----PVPPAPPL----------PGDSGTIIPPPPAPGDSTTPP---PP 611

Query: 201 GPPPGPPPP 209
            PPP PPPP
Sbjct: 612 PPPPPPPPP 620



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 62/240 (25%), Positives = 86/240 (35%), Gaps = 60/240 (25%)

Query: 141 LPDMPHAPSNILIQDIP--LPGAQ----PPSILKKTSAYGPPTRAVSILPLLGHGVPRLP 194
           +P  P  P +  I   P  LPG+     PP  L   +   PP   +      G G+P  P
Sbjct: 675 IPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPG----GPGIPPPP 730

Query: 195 PGRKPPGPPPGPP----PPQVVQMYGRKVGFAL--DLPPRRRDEDMLYSPELAQR--GHD 246
           P    PG PP PP    PP     +G      L   L P++     LY PE+  R     
Sbjct: 731 PFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKK-----LYKPEVQLRRPNWS 785

Query: 247 DDVSSTSEDDGYPEDMDQDKHDDS--------TDDSDTDKSDGESDGDEFVHRDNGERDN 298
             V+     D +   + +D+ +++        T  + T  S  + D           ++ 
Sbjct: 786 KLVAEDLSQDCFWTKVKEDRFENNELFAKLTLTFSAQTKTSKAKKD-----------QEG 834

Query: 299 NEEKKSGLSVRFADMPGKSRKKKKNMKELTPLQAMML-------RMAGQEIPEEGREVEE 351
            EEKKS             +KK K +K L    A  L       RM  QEI     EV E
Sbjct: 835 GEEKKS-----------VQKKKVKELKVLDSKTAQNLSIFLGSFRMPYQEIKNVILEVNE 883



 Score = 30.4 bits (67), Expect = 5.2
 Identities = 31/92 (33%), Positives = 35/92 (38%), Gaps = 23/92 (25%)

Query: 140 PLPDMPHAPSNILIQDIP-LPGA---QPPSILKKTSAYGPPTR--------AVSILPLLG 187
           P P  P  P  + I   P LPG     PP  L   +   PP          + S LP  G
Sbjct: 614 PPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPG-G 672

Query: 188 HGVPRLPP----GRKPPGPPP------GPPPP 209
             +P  PP     R PP PPP       PPPP
Sbjct: 673 TAIPPPPPLPGSARIPPPPPPLPGSAGIPPPP 704


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score =  102 bits (253), Expect = 1e-21
 Identities = 88/267 (32%), Positives = 111/267 (41%), Gaps = 40/267 (14%)

Query: 369 QSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPT 428
           QS  Q K  S  +  +        PP  VP SQ+       PPPL P   PP+ PP  P 
Sbjct: 493 QSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQM-------PPPL-PTMPPPVLPPSLP- 543

Query: 429 GLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPG-PPPGPPPGL-PPGPPPRG 486
             PP  PP  P  + PPGMP          PP  PP  P   PPPG PP L   GPPP  
Sbjct: 544 --PPVMPPALPATVPPPGMP----------PPVMPPSLPTSVPPPGMPPSLSSAGPPPVL 591

Query: 487 PPPRLPPPAPPGI-PPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGV-LSAPPNLIQR- 543
           PPP L    PP + PPP      PP V PL P      PP  +P PGV    PP L    
Sbjct: 592 PPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSAT-PPPGIPPPGVPQGIPPQLTAAP 650

Query: 544 -PKADDTSAATIEKKATATISAKPQITNPKAEITRFVPTALRVRRENKGATAAPQRKSED 602
            P A  + ++ + +K    +   P ++   A  T + P         +  + AP  K   
Sbjct: 651 VPPASSSQSSQVPEKPRPALLPTP-VSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSK--- 706

Query: 603 DSAVPLAKAAPKSG-------PSVPVS 622
            SA+P +  +   G       PS P++
Sbjct: 707 -SALPYSSFSSDQGLGESSAAPSQPIT 732



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 69/264 (26%), Positives = 100/264 (37%), Gaps = 68/264 (25%)

Query: 400 SQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGA--------------------- 438
           S    PP+P PPP+  P A P   PG  +   P  P  +                     
Sbjct: 12  SHYPPPPVPPPPPVALPEASP--GPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQ 69

Query: 439 ---PPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPP------------ 483
                 L+P  +P    P P ++P G      P PPP PP   PPGP             
Sbjct: 70  KQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPP---PPGPALSYQKQQQYKHQ 126

Query: 484 ----PRGPPPRLPP---PAPPGIPPPRPGMMRPP---LVPPLGPAPPGLFPPAPLPNPGV 533
                R  PP L P    +PP  PP  PG   PP    +PP  P PP  +PP     P +
Sbjct: 127 MLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQP-PPSYYPPTS-SQPYL 184

Query: 534 LSAPPNLIQRPKADDTSAATIEKKATATISAKPQITNPKAEITRFVPTALRVRRENKGAT 593
             A P+  Q P +    A T    ++++ S++  +++ ++    ++P+          + 
Sbjct: 185 PPAQPSPSQSPPSQSYLAPT-PSYSSSSSSSQSYLSHSQS----YLPS----------SQ 229

Query: 594 AAPQRKSEDDSAVPLAKAAPKSGP 617
           A+P R S+  S   L    P S P
Sbjct: 230 ASPSRPSQGHSKSQLLAPPPPSAP 253



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 49/161 (30%), Positives = 59/161 (36%), Gaps = 45/161 (27%)

Query: 370 SQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPG---------PPPLGPPPAPP 420
           +Q Q  ++ H             PP  +PP     P MPG         PPP+ PPP P 
Sbjct: 59  AQLQQLQQMHQKQMQCVLQPHHLPPPPLPPP----PVMPGGGYGDWQPPPPPMPPPPGPA 114

Query: 421 L---------------RPPGPPTGLPP---GPPPGAPPFLRPPGMPGLRGPLPRLLPPGP 462
           L               +  GPP GL P     PP +PP   PPG           +PP  
Sbjct: 115 LSYQKQQQYKHQMLHHQRDGPP-GLVPMELESPPESPPV--PPG---------SYMPPSQ 162

Query: 463 PPGRPPGPPPG--PPPGLPPGPPPRGPPPRLPPPAPPGIPP 501
               PP PPP   PP    P  PP  P P   PP+   + P
Sbjct: 163 SYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAP 203



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 48/161 (29%), Positives = 59/161 (36%), Gaps = 40/161 (24%)

Query: 397  VPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPR 456
            +PP + +       P + PPP    RPP PP G PPG        +  P  P  R  +P 
Sbjct: 1489 LPPQESRLQNTSSRPGMYPPPGS-YRPP-PPMGKPPGS-------IVRPSAPPARSSVPV 1539

Query: 457  LLPPGPPPGRPPGPP-PGPPPGLPP-------------------------GPPPRGPPPR 490
              PP P P  PP PP P PPP + P                         G         
Sbjct: 1540 TRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSET 1599

Query: 491  LPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNP 531
               P+ P +PPP         +PP GP P G+ PP   P P
Sbjct: 1600 AAIPSAPVLPPPPVHSS----IPPPGPVPMGM-PPMSKPPP 1635



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 85/352 (24%), Positives = 120/352 (34%), Gaps = 97/352 (27%)

Query: 197  RKPPGPPPGPPPPQVVQMYGRKVGFALDLPPRRRDEDMLYSPEL-AQRGHDDDVSSTSE- 254
            R  P  PP PP P               LPP  R  D  +  E   + G+D D     E 
Sbjct: 1326 RDIPSLPPLPPLPP--------------LPPLDRYRDDRWREERNREHGYDRDFRDRGEL 1371

Query: 255  -DDGYPEDMD--QDKHDDSTDDSDTDK---SDGESDGDEFVHRDNGERDNNEEKKSGLSV 308
                YPE  D  ++K D   D  D ++   SD     D   H    E   +    S +  
Sbjct: 1372 RIREYPERGDTWREKRDYVPDRMDWERERLSDRWYPSDVDRHSPMAEHMPSSHHSSEMMG 1431

Query: 309  RFADMPGKSRKKKKNMKELTPLQAMMLRMAGQEIP---EEGREVEEFSEDDDEDDSDDSE 365
              A +   S +    +  L+  Q  ++  A QE+    E+  ++++  +   E    D  
Sbjct: 1432 SDASLD--SDQGLGGVMVLSQRQHEIILKAAQELKMLREQKEQLQKMKDFGSEPQMADHL 1489

Query: 366  AEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPG 425
              ++S+ Q+         +++      PP S  P          PPP+G PP   +RP  
Sbjct: 1490 PPQESRLQN---------TSSRPGMYPPPGSYRP----------PPPMGKPPGSIVRPSA 1530

Query: 426  PPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRP------------------ 467
            PP          + P  RPP +P    P P  LPP PP  +P                  
Sbjct: 1531 PPAR-------SSVPVTRPP-VPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGL 1582

Query: 468  --------------------PGPPPGPPPGL-----PPGPPPRGPPPRLPPP 494
                                P  P  PPP +     PPGP P G PP   PP
Sbjct: 1583 WDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPP 1634



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 61/254 (24%), Positives = 75/254 (29%), Gaps = 95/254 (37%)

Query: 367 EKQSQKQHKEESHS-DGT-STASSQQQAPPQS--VPPSQIQAPPMPGPPPLGPPPA--PP 420
           +KQ Q +H+   H  DG       + ++PP+S  VPP     P     PP  PPP+  PP
Sbjct: 118 QKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPP 177

Query: 421 L--RPPGPPTGLPPGPPPGAPPFLRP----------------------------PGMPGL 450
              +P  PP    P   P +  +L P                            P  P  
Sbjct: 178 TSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQ 237

Query: 451 RGPLPRLLPPGPPPGRPPG-------------------------PPPGPP---------- 475
                +LL P PPP  PPG                         P P P           
Sbjct: 238 GHSKSQLLAP-PPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQY 296

Query: 476 -----------------PGLPPGP-----PPRGPPPRLPPPAPPGIPPPRPGMMRPPLVP 513
                            PG   GP      P      +  PA   + P  P    PPL P
Sbjct: 297 WYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQV-PESPSSEEPPLPP 355

Query: 514 PLGPAPPGLFPPAP 527
           P    PP L P  P
Sbjct: 356 PNEEVPPPLPPEEP 369



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 26/74 (35%), Positives = 33/74 (44%), Gaps = 18/74 (24%)

Query: 138 SIPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGR 197
           S+P P MP A    L   +P PG  PP +        PP+   S+ P      P +PP  
Sbjct: 541 SLPPPVMPPA----LPATVPPPGMPPPVM--------PPSLPTSVPP------PGMPPSL 582

Query: 198 KPPGPPPGPPPPQV 211
              GPPP  PPP +
Sbjct: 583 SSAGPPPVLPPPSL 596



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 27/75 (36%), Positives = 33/75 (44%), Gaps = 6/75 (8%)

Query: 138 SIPLPDMPHAPSNI----LIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRL 193
           S+P P MP + S+     ++    L  A PP +L   S        V  LP L    P  
Sbjct: 572 SVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATP-- 629

Query: 194 PPGRKPPGPPPGPPP 208
           PPG  PPG P G PP
Sbjct: 630 PPGIPPPGVPQGIPP 644



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 34/125 (27%), Positives = 57/125 (45%), Gaps = 12/125 (9%)

Query: 92   ILRLYEKENPDIYKELRKLEVEYEQKRA--QLSQYFDAVKNAQHVEVESIPLPDMPHAPS 149
            ++ L ++++  I K  ++L++  EQK    ++  +    + A H+  +   L +    P 
Sbjct: 1445 VMVLSQRQHEIILKAAQELKMLREQKEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPG 1504

Query: 150  NILIQDI---PLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGP 206
                      P P  +PP  + + SA  PP R  S +P+    VP  PP   PP PP  P
Sbjct: 1505 MYPPPGSYRPPPPMGKPPGSIVRPSA--PPAR--SSVPVTRPPVPIPPP---PPPPPLPP 1557

Query: 207  PPPQV 211
            PPP +
Sbjct: 1558 PPPVI 1562



 Score = 33.9 bits (76), Expect = 0.47
 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 12/87 (13%)

Query: 125 FDAVKNAQHVEVESIPLPDMPHAPSNILIQDIP---LPGAQPPSILKKTSAYGPPTRAVS 181
           F  +KN Q++   S+P P +P++     +  +P   LP + PP ++       PP    +
Sbjct: 503 FQNMKN-QYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVM-------PPALPAT 554

Query: 182 ILPLLGHGVPRLPPGRKPPGPPPGPPP 208
           + P  G   P +PP      PPPG PP
Sbjct: 555 VPPP-GMPPPVMPPSLPTSVPPPGMPP 580



 Score = 33.5 bits (75), Expect = 0.62
 Identities = 22/73 (30%), Positives = 30/73 (41%), Gaps = 7/73 (9%)

Query: 489  PRLPPPAPPGIPPP----RPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRP 544
            P + PP     PPP     PG +  P  PP   + P   PP P+P P     PP L   P
Sbjct: 1503 PGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPP---PPPPPLPPPP 1559

Query: 545  KADDTSAATIEKK 557
                   + +E++
Sbjct: 1560 PVIKPQTSAVEQE 1572



 Score = 31.6 bits (70), Expect = 2.4
 Identities = 32/134 (23%), Positives = 51/134 (38%), Gaps = 12/134 (8%)

Query: 169  KTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPPPQVVQMYGRKVGFALDLPPR 228
            K+     P+  V   P +   +P  PPG  P G PP   PP V Q      G   D+   
Sbjct: 1596 KSETAAIPSAPVLPPPPVHSSIP--PPGPVPMGMPPMSKPPPVQQTV--DYGHGRDISTN 1651

Query: 229  RRD-----EDMLYSPELAQRGHDDDVSSTSEDDGYPEDMDQDKHDDSTDDSDTDKSDGES 283
            + +     E +   P+        +     + D Y  + D++ + D   +   D  D + 
Sbjct: 1652 KVEQIPYGERITLRPDPLPERSTFETEHAGQRDRYDRERDREPYFDRQSNVIADHRDFKR 1711

Query: 284  DGDEFVHRDNGERD 297
            D +   HRD  +RD
Sbjct: 1712 DRE--THRDR-DRD 1722



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 15/38 (39%), Positives = 16/38 (42%), Gaps = 2/38 (5%)

Query: 453 PLPRLLPPGPPPGRPPGPPPGP--PPGLPPGPPPRGPP 488
           P    +P  P    PP PPP    PP LPP  P    P
Sbjct: 337 PATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDP 374



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 17/47 (36%), Positives = 24/47 (51%), Gaps = 4/47 (8%)

Query: 379  HSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPP---APPLR 422
            +S+  S  ++   AP    PP     PP PGP P+G PP    PP++
Sbjct: 1592 NSEFKSETAAIPSAPVLPPPPVHSSIPP-PGPVPMGMPPMSKPPPVQ 1637


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score =  101 bits (252), Expect = 2e-21
 Identities = 60/127 (47%), Positives = 63/127 (49%), Gaps = 17/127 (13%)

Query: 389 QQQAPPQSVPPSQIQAPPMPGPPP--LGPPP-------APPLRPPGPPTGLPPGPPPGAP 439
           ++QAPP   PP     PP P PPP   GPPP       APP  P   PT  PP PPP  P
Sbjct: 273 RRQAPPP--PPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRP 330

Query: 440 PFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGI 499
               PP  P    P P   PP  P   P GPPP PP  L  GP    PPP  PPP PPG 
Sbjct: 331 SVAVPPPPPNRMYPPP---PPALPSSAPSGPPPPPPSVLGVGPV--APPPPPPPPPPPG- 384

Query: 500 PPPRPGM 506
           PPP PG+
Sbjct: 385 PPPPPGL 391



 Score = 95.9 bits (237), Expect = 1e-19
 Identities = 64/144 (44%), Positives = 66/144 (45%), Gaps = 27/144 (18%)

Query: 403 QAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPP----GAPPFLRPPGMPGLRGPLPRLL 458
           QAPP P P   GPPP PP     PP    P PPP    GAPP   PP         P   
Sbjct: 275 QAPPPPPPSRGGPPPPPP-----PPHNSGPPPPPARGRGAPP--PPPSRA------PTAA 321

Query: 459 PPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRP-----GMMRPPLVP 513
           PP PPP RP    P PPP     PPP    P LP  AP G PPP P     G + PP  P
Sbjct: 322 PPPPPPSRPSVAVPPPPPNRMYPPPP----PALPSSAPSGPPPPPPSVLGVGPVAPPPPP 377

Query: 514 PLGPAPPGLFPPAPLPNPGVLSAP 537
           P  P PPG  PP  LP+ G    P
Sbjct: 378 P-PPPPPGPPPPPGLPSDGDHQVP 400



 Score = 86.7 bits (213), Expect = 6e-17
 Identities = 57/129 (44%), Positives = 61/129 (47%), Gaps = 21/129 (16%)

Query: 421 LRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLP-----RLLPPGPPPGRPPGPPPGPP 475
           LR   PP   PP P  G PP   PP  P   GP P     R  PP PP   P   PP PP
Sbjct: 272 LRRQAPP---PPPPSRGGPP--PPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPP 326

Query: 476 PGLP----PGPPPR----GPPPRLPPPAPPGIPPPRPGMMR-PPLVPPLGPAPPGLFPPA 526
           P  P    P PPP      PPP LP  AP G PPP P ++   P+ PP  P PP   PP 
Sbjct: 327 PSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPP--PPG 384

Query: 527 PLPNPGVLS 535
           P P PG+ S
Sbjct: 385 PPPPPGLPS 393



 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 47/113 (41%), Positives = 54/113 (47%), Gaps = 21/113 (18%)

Query: 446 GMPGLRGPLPRLLPPGPPPGRPPGPPPGPPP---GLPPGPPPRG------PPPRLPPPAP 496
           G+  ++  L R  PP PPP R  GPPP PPP     PP PP RG      PP R P  AP
Sbjct: 264 GVEAVKNELRRQAPPPPPPSR-GGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAP 322

Query: 497 PGIPPPRPGMMRPP-----LVPPLGPAPPGLFPPAPLPNP------GVLSAPP 538
           P  PP RP +  PP     + PP  PA P   P  P P P      G ++ PP
Sbjct: 323 PPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPP 375



 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 41/87 (47%), Positives = 44/87 (50%), Gaps = 6/87 (6%)

Query: 393 PPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRG 452
           PP S  P+    PP P  P +  PP PP R   PP   PP  P  AP    PP  P + G
Sbjct: 312 PPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPP---PPALPSSAPSG-PPPPPPSVLG 367

Query: 453 PLPRLLPPGPPPGRPPGPPPGPPPGLP 479
             P   PP PPP  PPGPP  PPPGLP
Sbjct: 368 VGPVAPPPPPPPPPPPGPP--PPPGLP 392



 Score = 38.1 bits (87), Expect = 0.025
 Identities = 26/73 (35%), Positives = 31/73 (42%), Gaps = 5/73 (6%)

Query: 140 PLPDMPHAPSNILIQDIPLPGAQ---PPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPG 196
           P P  P  PS  +    P P      PP  L  ++  GPP    S+L +     P  PP 
Sbjct: 322 PPPPPPSRPS--VAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPP 379

Query: 197 RKPPGPPPGPPPP 209
             PPGPPP P  P
Sbjct: 380 PPPPGPPPPPGLP 392



 Score = 37.0 bits (84), Expect = 0.056
 Identities = 22/53 (41%), Positives = 22/53 (41%), Gaps = 12/53 (22%)

Query: 387 SSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAP 439
           SS    PP   P      P  P PPP      PP  PPGPP      PPPG P
Sbjct: 352 SSAPSGPPPPPPSVLGVGPVAPPPPP------PPPPPPGPP------PPPGLP 392



 Score = 35.4 bits (80), Expect = 0.16
 Identities = 21/45 (46%), Positives = 23/45 (51%), Gaps = 3/45 (6%)

Query: 384 STASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPT 428
           S+A S    PP SV      APP P PPP  P P P   PPG P+
Sbjct: 352 SSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPP---PPGLPS 393



 Score = 34.7 bits (78), Expect = 0.28
 Identities = 19/49 (38%), Positives = 19/49 (38%), Gaps = 7/49 (14%)

Query: 160 GAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPP 208
           G  PP      S   PP       P  G G P  PP R P   PP PPP
Sbjct: 286 GPPPPPPPPHNSGPPPP-------PARGRGAPPPPPSRAPTAAPPPPPP 327



 Score = 30.4 bits (67), Expect = 5.2
 Identities = 31/108 (28%), Positives = 37/108 (34%), Gaps = 29/108 (26%)

Query: 126 DAVKNAQHVEVESIPLPDM------PHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRA 179
           +AVKN    +    P P        P  P N         G  PP    + +   PP+RA
Sbjct: 266 EAVKNELRRQAPPPPPPSRGGPPPPPPPPHN--------SGPPPPPARGRGAPPPPPSRA 317

Query: 180 VSILP------LLGHGVPRLPPGRKPPGPPPG---------PPPPQVV 212
            +  P           VP  PP R  P PPP          PPPP  V
Sbjct: 318 PTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSV 365



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 20/52 (38%), Positives = 22/52 (42%), Gaps = 7/52 (13%)

Query: 495 APPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKA 546
           APP  PP R G       PP  P PP    P P P  G  + PP   + P A
Sbjct: 276 APPPPPPSRGG-------PPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTA 320


>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
          Length = 464

 Score =  100 bits (249), Expect = 4e-21
 Identities = 74/207 (35%), Positives = 89/207 (42%), Gaps = 36/207 (17%)

Query: 398 PPSQIQAPPMPGPPPLGPPPAP---PLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPL 454
           PP     PP P  P   PPP P   PL PP PPTG  P  PPG P    PP  PG+  P 
Sbjct: 235 PPLMNGLPPRPPLPESLPPPPPGGLPL-PPMPPTGPAPSGPPGPPQL--PPPAPGVHPPA 291

Query: 455 PRLLPPG-----PPPG-RPPGPPPGPP-PGL--------PPGPPPRGPPPRLPPPAP--- 496
           P + PP      P PG  PP P   PP PG+        PP P    P P + PPAP   
Sbjct: 292 PVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVH 351

Query: 497 ---PGIPPPRPGMMRP------PLVPPLGPAPPGLFPPAP---LPNPGVLSAPPNLIQRP 544
              PG+ PP PG+  P      P  P + PA P + P AP    P PG+    P +  +P
Sbjct: 352 PPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQP 411

Query: 545 KADDTSAATIEKKATATISAKPQITNP 571
                SA  +  +      + P +  P
Sbjct: 412 PGVHPSAPGVHPQPPGVHPSNPGVHPP 438



 Score = 97.8 bits (242), Expect = 3e-20
 Identities = 70/173 (40%), Positives = 82/173 (47%), Gaps = 36/173 (20%)

Query: 401 QIQAPPMPGPPPLGPPPAPPLRPPGP-PTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLP 459
           +++ PP P   P GPP     RPP P   GLPP PP   P  L PP   GL  PLP + P
Sbjct: 213 KMEKPPAPPSLPAGPPGVK--RPPPPLMNGLPPRPP--LPESLPPPPPGGL--PLPPMPP 266

Query: 460 PGPPPGRPPGPP--PGPPPGL---------------PPGPPPRGPPPRLPPPAP------ 496
            GP P  PPGPP  P P PG+               PP P    P P + PPAP      
Sbjct: 267 TGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPT 326

Query: 497 PGIPPPRPGMMRPPLVPPLGPAPPGLFPPAP---LPNPGVLSAPPNLIQRPKA 546
            G+ PP PG+  P   P + P  PG+ PPAP    P PGV   PP+    P+A
Sbjct: 327 SGVHPPAPGVHPP--APGVHPPAPGVHPPAPGVHPPAPGV-HPPPSAGVHPQA 376



 Score = 96.7 bits (239), Expect = 6e-20
 Identities = 66/170 (38%), Positives = 81/170 (47%), Gaps = 26/170 (15%)

Query: 394 PQSVPPSQIQAPPMPGPPPLGP----PPAPPLRPPGPPTGLPPGP---PPGA-----PPF 441
           P+S+PP      P+P  PP GP    PP PP  PP  P   PP P   PP +      P 
Sbjct: 248 PESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPG 307

Query: 442 LRPPGMPGLRGPLPRLLPPG-----PPPG-RPPGPPPGPP-PGL-PPGPPPRGPPPRLPP 493
           + PP  PG+  P P + PP      P PG  PP P   PP PG+ PP P    P P + P
Sbjct: 308 VHPPA-PGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHP 366

Query: 494 PAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPN---PGVLSAPPNL 540
           P   G+ P  PG+   P  P + P  PG+ PPAP  +   PGV   PP +
Sbjct: 367 PPSAGVHPQAPGV--HPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGV 414



 Score = 96.3 bits (238), Expect = 8e-20
 Identities = 72/174 (41%), Positives = 83/174 (47%), Gaps = 29/174 (16%)

Query: 389 QQQAPPQSVPPSQIQAPP--MPGPPPL--GPPPAPPLR---PPGPPTGLP-PGPPPGAPP 440
           + + PP   PPS    PP     PPPL  G PP PPL    PP PP GLP P  PP  P 
Sbjct: 213 KMEKPP--APPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPA 270

Query: 441 FLRPPGMPGLRGPLPRLLPPGP---PPG---RPPGPPPGPP-PGL-PPGPPPRGPPPRLP 492
              PPG P L  P P + PP P   PP     PP P   PP PG+ PP P    P   + 
Sbjct: 271 PSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVH 330

Query: 493 PPAP------PGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNL 540
           PPAP      PG+ PP PG+  P   P + P  PG+ PP   P+ GV    P +
Sbjct: 331 PPAPGVHPPAPGVHPPAPGVHPP--APGVHPPAPGVHPP---PSAGVHPQAPGV 379



 Score = 93.6 bits (231), Expect = 5e-19
 Identities = 68/171 (39%), Positives = 78/171 (45%), Gaps = 22/171 (12%)

Query: 383 TSTASSQQQAPPQSVPPSQIQAPPMP--GPPPLG-PPPAPPLRPPGPPTGLPPGPPPGAP 439
           T  A S    PPQ  PP+    PP P   PP  G  PPAP + PP P  G+ P  P   P
Sbjct: 267 TGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAP--GVHPPAPGVHP 324

Query: 440 PF--LRPPGMPGLRGPLPRLLPPGP---PPG---RPPGPPPGPPPGLPPGPPPRGPPPRL 491
           P   + PP  PG+  P P + PP P   PP     PP P   PPP     P   G  P  
Sbjct: 325 PTSGVHPPA-PGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAA 383

Query: 492 PP--PAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNL 540
           P   P  PG+ PP PGM   P  P + P PPG+ P A    PGV   PP +
Sbjct: 384 PAVHPQAPGVHPPAPGM--HPQAPGVHPQPPGVHPSA----PGVHPQPPGV 428



 Score = 83.6 bits (205), Expect = 5e-16
 Identities = 63/170 (37%), Positives = 71/170 (41%), Gaps = 23/170 (13%)

Query: 386 ASSQQQAPPQSVPPSQIQAPPMPG--PPPLGP-PPAPPLRPPGPPTGLP-PGPPPGAP-- 439
           AS      P   PP+    PP PG  PP  G  PPAP + PP P    P PG  P AP  
Sbjct: 298 ASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGV 357

Query: 440 ----PFLRPPGMPGLRGPLPRLLPPGPP--PGRPPGPPPGP-----PPGLPPGPPPRGPP 488
               P + PP   G+    P + P  P   P  P   PP P      PG+ P PP   P 
Sbjct: 358 HPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPS 417

Query: 489 PRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPP 538
                P PPG+ P  PG      V P  P PP L PP P   PG +  PP
Sbjct: 418 APGVHPQPPGVHPSNPG------VHPPTPMPPMLRPPLPSEGPGNIPPPP 461



 Score = 34.3 bits (77), Expect = 0.36
 Identities = 28/85 (32%), Positives = 35/85 (41%), Gaps = 6/85 (7%)

Query: 133 HVEVESIPLP-DMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHG-V 190
           H ++E  P P  +P  P  +     PL    PP      S   PP   + + P+   G  
Sbjct: 211 HFKMEKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPA 270

Query: 191 PRLPPGRKPPGPPPGP---PPPQVV 212
           P  PPG  P  PPP P   PP  VV
Sbjct: 271 PSGPPG-PPQLPPPAPGVHPPAPVV 294



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 21/57 (36%), Positives = 23/57 (40%), Gaps = 5/57 (8%)

Query: 157 PLPGAQPPS--ILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPPPQV 211
           P PG  PP+  +   TS   PP   V        GV    PG  PP P   PP P V
Sbjct: 311 PAPGVHPPAPGVHPPTSGVHPPAPGVHPP---APGVHPPAPGVHPPAPGVHPPAPGV 364


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 98.6 bits (244), Expect = 2e-20
 Identities = 88/285 (30%), Positives = 107/285 (37%), Gaps = 51/285 (17%)

Query: 394  PQSVPPSQIQAPPMPG-----PPPLGPPPAPPLRPPGPPTGLPPGPPPGAP--PFLRPPG 446
            P+  P +    PP P      P P G P  P   PP P  G    PP GAP  P   PP 
Sbjct: 1214 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPS 1273

Query: 447  MPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAP---PGIPPPR 503
            + G     P    P P    PP P  GP    P G P    PP   PP+P   PG PPP+
Sbjct: 1274 LKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPT---PPAATPPSPKGSPGTPPPK 1330

Query: 504  PGMMRPPLVPPL----------------GPAPP----GLFPPAPLPN--PGVLSAPPN-- 539
                 P + PP                 GP  P    G  PPA  P+   G    PP+  
Sbjct: 1331 GAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPK 1390

Query: 540  ---LIQRPKADDTSAATI---EKKATAT-ISAKPQITNPKAEITRFVPTALRVRRENKGA 592
                I  PK D TS A I    KKA AT ++ +   T  K ++T   P    V  +   A
Sbjct: 1391 RGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLT--PPAVTPVSLKKAPA 1448

Query: 593  TAAPQ-----RKSEDDSAVPLAKAAPKSGPSVPVSVQTKDDVYEA 632
            T+AP+       S+ D  +P         P  P  V T     +A
Sbjct: 1449 TSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKA 1493



 Score = 85.9 bits (211), Expect = 1e-16
 Identities = 90/295 (30%), Positives = 111/295 (37%), Gaps = 70/295 (23%)

Query: 378  SHSDGTSTASSQ-QQAPPQSVPPSQIQAPPMPGP-----PPLGPPPAP--------PLRP 423
            S   G +T S +    PP + PPS    P  P P     PP   PP+P        P   
Sbjct: 949  SPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGA 1008

Query: 424  PGPPTGLPPGP---------PPGA--PPFLRPPGMPGLRG--PLPRLLPPGP------PP 464
            P PP   PP P         P GA  PP   PP   G     PLP+  P  P      P 
Sbjct: 1009 PTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPK 1068

Query: 465  GRP--------PGPPPGPPP---GLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVP 513
            G P        P PP   PP   G P  P P+G P  +PP A P  P P+ G+  PP   
Sbjct: 1069 GGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAP--MPPAATP--PSPKGGLATPP--H 1122

Query: 514  PLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSAATIEKKATATISAKPQITNPKA 573
               P  P   PP+P    G L+ PP     PK   T+ A         ++  P    PK 
Sbjct: 1123 KGAPTTPAATPPSP---KGGLATPP-----PKGAPTTPAATPPSPKGGLATPP----PKG 1170

Query: 574  EITRFVPTALRVRRENKGATAAPQRKSEDDSAVP------LAKAAPKSGPSVPVS 622
              T   P A     +   AT +P+      +A P      LA  +PK  P+ P +
Sbjct: 1171 APT--TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1223



 Score = 84.3 bits (207), Expect = 3e-16
 Identities = 82/282 (29%), Positives = 98/282 (34%), Gaps = 60/282 (21%)

Query: 393  PPQSVPPSQIQAPPMPG-----PPPLGPPPAPPLRPPGPPTGLPPGPPPGAP--PFLRPP 445
            P +  P +    PP P      PPP G P  P   PP P  GL   PP GAP  P   PP
Sbjct: 1121 PHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1180

Query: 446  GMPG-LRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPP--PRLPPPAPPG---I 499
               G L  P P+       P  P   PP P  GL   P P+G P  P   PP+P G    
Sbjct: 1181 SPKGGLATPSPK-----GAPTTPAATPPSPKGGLAT-PSPKGAPTTPAATPPSPKGGLAT 1234

Query: 500  PPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNP---------GVLSAPPN------LIQRP 544
            P P+     P   PP     P   PP   P P         G L+ PP+       +  P
Sbjct: 1235 PSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP 1294

Query: 545  KADDTSAATIEKKATATISA--------KPQITNPKAEIT---------RFVPTALRVRR 587
             +     AT   K   T  A         P    PK   T         +  PT      
Sbjct: 1295 PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP 1354

Query: 588  ENKGATAAPQRKS--EDDSAVPLAKA-------APKSGPSVP 620
             +KG    P  K      +A P  K        +PK GP++P
Sbjct: 1355 SSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIP 1396



 Score = 82.8 bits (203), Expect = 9e-16
 Identities = 80/248 (32%), Positives = 92/248 (37%), Gaps = 34/248 (13%)

Query: 383  TSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLP---PGPPPGAP 439
            TS++  + +A P    P  I A P P   P  P   PP    GP T  P   P PP   P
Sbjct: 914  TSSSPKKARATPA---PKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATP 970

Query: 440  PFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGI 499
            P   P G P    P      P PP   PP P  GP    P G P    PP + PP+P G 
Sbjct: 971  P--SPKGGPATPSPKGA---PTPPAATPPSPKGGPATPSPKGAPT---PPAVTPPSPKGS 1022

Query: 500  PPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSAATI--EKK 557
            P   P        P     PP   PP+P  +P     P        A  T AAT+   K 
Sbjct: 1023 PAATP-------FPKGASTPPAATPPSPKGSPAATPLPKG------APTTPAATLPSPKG 1069

Query: 558  ATATISAKPQITNPKAEITRFVPTALRVRRENKGA---TAAPQRKSEDDSAVPLAKAAPK 614
              AT S K   T P A  T   P         KGA    AA     +   A P  K AP 
Sbjct: 1070 GPATPSLKGAPTPPAA--TPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPT 1127

Query: 615  SGPSVPVS 622
            +  + P S
Sbjct: 1128 TPAATPPS 1135



 Score = 82.4 bits (202), Expect = 1e-15
 Identities = 84/286 (29%), Positives = 100/286 (34%), Gaps = 41/286 (14%)

Query: 378  SHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPP-PLGPPPAP-PLRPPGPPTGLPPGPP 435
            S S   + A+   +  P S  P     PP   PP P G P  P P   P PP   PP P 
Sbjct: 915  SSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPK 974

Query: 436  --PGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPP---PGPPPGLPPGPP-PRG--P 487
              P  P     P  P    P P+  P  P P   P PP   P  P G P   P P+G   
Sbjct: 975  GGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAST 1034

Query: 488  PPRLPPPAPPGIP---------PPRPGMMRP-----PLVPPL--GPAPPGLFPPAPLPNP 531
            PP   PP+P G P         P  P    P     P  P L   P PP   PP+P   P
Sbjct: 1035 PPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGP 1094

Query: 532  GVLS---APPNLIQRPKADDTSAATIEKKATATI------SAKPQITNPKAEITRFVPTA 582
               S   AP      P +     AT   K   T       S K  +  P  +     P A
Sbjct: 1095 ATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA 1154

Query: 583  LRVRRENKGATAAPQRKSEDDSAVP------LAKAAPKSGPSVPVS 622
                 +   AT  P+      +A P      LA  +PK  P+ P +
Sbjct: 1155 TPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1200



 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 75/240 (31%), Positives = 87/240 (36%), Gaps = 33/240 (13%)

Query: 393  PPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRG 452
            PP + PPS    P  P P   G P  P   PP P  GL   P  GAP        P    
Sbjct: 1082 PPAATPPSPKGGPATPSPK--GAPMPPAATPPSPKGGLATPPHKGAPT------TPAATP 1133

Query: 453  PLPRLLPPGPPPGRPPGPPPGPPPGLPPG---PPPRGPPPRLPPPAPPGIPPPRPGMMRP 509
            P P+     PPP   P  P   PP    G   PPP+G P    P A P  P P+ G+  P
Sbjct: 1134 PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAP--TTPAATP--PSPKGGLATP 1189

Query: 510  PLVPPLGPAPPGLFPPAP---LPNPGVLSAPPNLIQRPKADDTSAATIEKKATATISAK- 565
               P   P  P   PP+P   L  P    AP      P +     AT   K   T  A  
Sbjct: 1190 S--PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1247

Query: 566  -------PQITNPKAEITRFVPTALRVRRENKGATAAPQRKSEDDSAVPLAKAAPKSGPS 618
                   P    PK   T    T   +    KG  A P  K   + AV +   +PK GP+
Sbjct: 1248 PPSPKGGPATPPPKGAPTPPAATPPSL----KGGLATPPHKGAPNPAV-VTPPSPKGGPA 1302



 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 79/264 (29%), Positives = 102/264 (38%), Gaps = 41/264 (15%)

Query: 393  PPQSVPPSQ---IQAPP----------MPGPPPLGPPPAPPLRPPGPPTGLPPGPP--PG 437
            PP + PPS    +  PP           P  P  GP  +PP   P PP   PP P   PG
Sbjct: 1266 PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPG 1325

Query: 438  APPFLRPPGMPGLRGPLPRLLP--PGPPPGRPPGPP-----PGPPPGLPPGPPPRGPPPR 490
             PP    P  P +  P P+  P  P   P    GP       GP P  P   P     P 
Sbjct: 1326 TPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTP--PAATPSHKGGPA 1383

Query: 491  LPPPAP---PGIPPPRPGMMRP---PLVPPLGPAPPGLFPPAPLPNPGVLSAPP-NLIQR 543
            + PP+P   P IP P+     P   PL P   PA P     A  P+ G L+ P    +  
Sbjct: 1384 MTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSL 1443

Query: 544  PKADDTSA-----ATIEKKATATISAKPQITNPKAEITRFVPTALRVRRENKGATAAPQR 598
             KA  TSA     AT   K   T+ A    +  +    + V T+   ++    AT AP  
Sbjct: 1444 KKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKK--APATPAPMG 1501

Query: 599  KSEDDSAVPLAKAAPKSGPSVPVS 622
                 + +P   ++PK  P+ P S
Sbjct: 1502 APTLPAVIP---SSPKEVPATPSS 1522



 Score = 76.6 bits (187), Expect = 6e-14
 Identities = 74/271 (27%), Positives = 89/271 (32%), Gaps = 36/271 (13%)

Query: 369  QSQKQHKEESHSD------GTSTASSQQQAPPQSV--PPSQIQAPPMPGPPPLGPPPAPP 420
            Q  K     +HS       G  T S+     P+ V  PP +   P +   P     PA P
Sbjct: 844  QGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP 903

Query: 421  LRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPP 480
                 P   +    P  A     P G+P    P     PP   P  P G P  P P   P
Sbjct: 904  APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP 963

Query: 481  GPPPRGPP-----PRLP----PPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNP 531
             PP   PP     P  P     P PP   PP P        P   P PP + PP+P  +P
Sbjct: 964  TPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSP 1023

Query: 532  GVLSAPPNLIQRPKADDTSAATIEKKATATISAKPQITNPKAEITRFVPTALRVRRENKG 591
                 P      P A   S    +    AT   K   T P A +              KG
Sbjct: 1024 AATPFPKGASTPPAATPPSP---KGSPAATPLPKGAPTTPAATLP-----------SPKG 1069

Query: 592  ATAAPQRKS--EDDSAVPLAKAAPKSGPSVP 620
              A P  K      +A P    +PK GP+ P
Sbjct: 1070 GPATPSLKGAPTPPAATP---PSPKGGPATP 1097



 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 82/288 (28%), Positives = 103/288 (35%), Gaps = 64/288 (22%)

Query: 393  PPQSVPPSQIQAPPMP-GPPPLGPP---PAPPLRPPGPPTGLPPGPPP-GAP--PFLRPP 445
            P +  P   +  PP P G P   PP   P PP   P  P G P  PPP GAP  P + PP
Sbjct: 1282 PHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPP 1341

Query: 446  ---GMPGL-----------------RGPLPRLLPP---GPPPGRPPGPPPGP----PPGL 478
               G P L                  GP P    P   G P   PP P  GP    P G 
Sbjct: 1342 SPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGD 1401

Query: 479  PPGPPPRGPPPRLPPPAP---PGIPPPRPGMMRPPLVPPL-------------GPAPPGL 522
            P  P      P+  P  P    G   P  G + PP V P+             GPA P  
Sbjct: 1402 PTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSS 1461

Query: 523  FPPAPLPNPGVLSAPPNLIQRPKADDTSAATIEKKATATISAKPQITNPKA--EITRFVP 580
                 LP       PP+  + P     + ++  KKA AT +     T P       + VP
Sbjct: 1462 KGDPTLP----AVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVP 1517

Query: 581  TALRVRRENKGATA------APQRKSEDDSAVPLAKA--APKSGPSVP 620
                 RR+    TA       P   +  ++ +P A    +PK  P++P
Sbjct: 1518 ATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIP 1565



 Score = 69.7 bits (169), Expect = 8e-12
 Identities = 75/253 (29%), Positives = 99/253 (39%), Gaps = 24/253 (9%)

Query: 378  SHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAP-PLRPPGPPTGLPPGPPP 436
            S   G +T SS++   P +  PS    P M  P P   P  P P   P  P  +P  P  
Sbjct: 1355 SSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKK 1414

Query: 437  G-APPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPP--PRLPP 493
              A P  R       +G L    P   P      P    P G P  P  +G P  P + P
Sbjct: 1415 APATPVTREGAATPSKGDLTP--PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTP 1472

Query: 494  PAPPGIPPPRP-GMMRPPLVPPLGPAPPGL-FPPAPLP-NPGVLSAPPNLIQRPKADDTS 550
            P+P   P P+       P   P  PAP G    PA +P +P  + A P+  + P A   +
Sbjct: 1473 PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIA--PT 1530

Query: 551  AATIEKKATATISAK-----PQITNPKAEITRFVPTALRVRRENKGATAAPQRKSEDDSA 605
            A  + KK  AT++ K     P +T P  + T  +PT        K A A P  K E  S 
Sbjct: 1531 ATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTP-------KEAPATPSSK-EASSP 1582

Query: 606  VPLAKAAPKSGPS 618
              +  +  K  PS
Sbjct: 1583 PAVTPSTYKGAPS 1595



 Score = 66.2 bits (160), Expect = 9e-11
 Identities = 80/324 (24%), Positives = 109/324 (33%), Gaps = 88/324 (27%)

Query: 381  DGTSTASSQQQAPPQSVPPSQIQAP----PMPG---PPPLGPPPAPPLRPPGPPTGLPPG 433
            +G +T S     PP   P S  +AP    P  G   P   G P  P + PP P    PP 
Sbjct: 1423 EGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKE--PPA 1480

Query: 434  P--------PPGAPPFLRPPGMPGLRGPLP------------------------------ 455
            P        P  AP    P G P L   +P                              
Sbjct: 1481 PKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPA 1540

Query: 456  ------RLLPPG---PPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGM 506
                   L+PP    P P + P  P        P       PP + P    G P P+  +
Sbjct: 1541 TLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKE-L 1599

Query: 507  MRPPLV----PPLGPAPPGLFPPAPLPNP------GVLSAPPNLIQRPKADDTSAATIEK 556
            + PP V    P   P PP + PP+P   P      G  ++PP      K   TS A++  
Sbjct: 1600 LIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTC 1659

Query: 557  KATATI--------------SAKPQITNPKAEITRFVPTALRVRRENKGATA-----APQ 597
            K  AT+              + K  +  P  E T  +    R   + K ++A      P 
Sbjct: 1660 KMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPD 1719

Query: 598  RKSEDDSAVPLAKAAPKSGPSVPV 621
              +++ S  PL+  AP   P +PV
Sbjct: 1720 PSAKNGSKGPLSTVAP--APLLPV 1741



 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 72/297 (24%), Positives = 100/297 (33%), Gaps = 66/297 (22%)

Query: 386  ASSQQQAPPQSVPPSQIQAPPMPGPP---------PLGPPPAPP---------------L 421
            A+   +  P   PPS  + P +P P          PL P  AP                L
Sbjct: 1374 ATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDL 1433

Query: 422  RPPG---------PPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPP 472
             PP          P T  P G P   P     P +P +  P P+      PP        
Sbjct: 1434 TPPAVTPVSLKKAPATSAPKGGP-ATPSSKGDPTLPAVTPPSPK-----EPPAPKQVATS 1487

Query: 473  GPPPGLPPGPPPRGPP--PRLPPPAPPGIPPPRPGMMRPPLVP---------PLGPAP-P 520
              P   P  P P G P  P + P +P  + P  P   R P+ P         P   AP  
Sbjct: 1488 SSPKKAPATPAPMGAPTLPAVIPSSPKEV-PATPSSRRDPIAPTATLLSKKTPATLAPKE 1546

Query: 521  GLFPPA-PLPNPGVLSAPPNLIQRPKADDTSAATIEKKATAT----------ISAKPQIT 569
             L PPA  +P+P    A P   + P    +  A+     T +          +   P +T
Sbjct: 1547 ALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVT 1606

Query: 570  NPKAEITRFVPTALRVRRENKGATAAPQRKSEDDSAVPLAKAAPKSGPSVPVSVQTK 626
            +P  +     P       E   AT AP+      ++ P+  ++ K  P+ P SV  K
Sbjct: 1607 SPSPKEAPTPPAVTPPSPEKGPATPAPK---GTPTSPPVTPSSLKDSPTSPASVTCK 1660



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 70/293 (23%), Positives = 106/293 (36%), Gaps = 67/293 (22%)

Query: 381  DGTSTASSQQQAPPQSVPPSQIQAPPMP----------GPPPLGPPPAPPLRPP----GP 426
            +  +T SS++ + P +V PS  +  P P           P P   P  P + PP    GP
Sbjct: 1569 EAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGP 1628

Query: 427  PTGLP---PGPPPGAPPFLR-----PPGMPGLRGPLPRLLPPGPPPGRPP--------GP 470
             T  P   P  PP  P  L+     P  +    G        G P  + P         P
Sbjct: 1629 ATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAP 1688

Query: 471  PPGPPPGLPPGPPPRGP---------PPRLP-PPAPPGIPPPRPGMMRPPLVP------- 513
             P   P +   P  +GP         PP  P P A  G   P   +   PL+P       
Sbjct: 1689 APESTP-IITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSK 1747

Query: 514  ----------PLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSAATIEKKATATIS 563
                      P GP  P   P +    P   +A   ++ +P++   SAA      +  ++
Sbjct: 1748 TAKGKDASHSPKGPLAP---PESKASTPLTAAAFEKVLPKPESASVSAAP-SPPVSLPLA 1803

Query: 564  AKPQITNPKAEITRFVPTALRVRRENKGATAAPQRKSEDDSAVPLAKAAPKSG 616
              P  T P  +  +F+P++  +  E+     AP   +++D  +PL    P SG
Sbjct: 1804 PSPVPTLPPKQ--QFLPSSPGLVLESPSKPLAP---ADEDELLPLIPPEPISG 1851



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 60/216 (27%), Positives = 76/216 (35%), Gaps = 19/216 (8%)

Query: 386 ASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAP-PFLRP 444
           A+    A  Q +P  Q +   +P    L    A  L  PGP       PPP +P P   P
Sbjct: 5   ATETVPATEQELPQPQAETAVLPMSSALSVTAA--LGQPGPTL-----PPPCSPAPQQCP 57

Query: 445 PGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGP---PPRLPPPAPPGIPP 501
                   P P        P   P P       LP G  P  P   P  + PP  P    
Sbjct: 58  LSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALA 117

Query: 502 PRPGMMRPPLV-PPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSAATIEKKATA 560
               M+ P L   P   AP  L   AP       + PPNL+  P     S A  E  +  
Sbjct: 118 LASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSP----PSVAVAESGSVI 173

Query: 561 TISAKPQITNPKAEITRFVPTALRVRRENKGATAAP 596
           T+SA    + PK  + + VP+   V    KG  + P
Sbjct: 174 TLSAPIAPSEPKTNLNK-VPS--EVVPNPKGTPSPP 206



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 68/266 (25%), Positives = 84/266 (31%), Gaps = 57/266 (21%)

Query: 399 PSQIQAPPMPGPPPLGPPP--------------APPLRPP-----------------GPP 427
           P   ++ P P  PP G PP              AP    P                 G  
Sbjct: 728 PEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTL 787

Query: 428 TGLPPGPPP----GAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGP-PPGPPPGLPPGP 482
           T L   P P     +P   RPP   G  G       P  P G    P  P     LP   
Sbjct: 788 TYLADSPSPLGVSVSPQTKRPPTKKGSAG-------PDTPIGNLSSPVSPVEASFLPENS 840

Query: 483 PPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAP----- 537
                    P       PP   G   P  V PL P    L PP   P P V++ P     
Sbjct: 841 LSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTL-PPKETPTPSVVNLPFPKEG 899

Query: 538 ---PNLIQRPKADDTSAATIEKKATATISAKPQITNPKAEITRFVPTALRVRRENKGATA 594
              P   Q P    TS++  + +AT      P   +PK   T   P A     +   AT 
Sbjct: 900 PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPT--PPAATPPSPKGGPATP 957

Query: 595 APQRKSEDDSAVPLAKAAPKSGPSVP 620
           +P+      +A P    +PK GP+ P
Sbjct: 958 SPKWAPTPPAATP---PSPKGGPATP 980



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 45/149 (30%), Positives = 59/149 (39%), Gaps = 16/149 (10%)

Query: 367  EKQSQK--QHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPP 424
            +K S K  + K+ SHS     A  + +A       +  +  P P    +   P+PP+  P
Sbjct: 1742 QKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLP 1801

Query: 425  GPPTGLPPGPPPGAPP---FLRPPGMPGLRGPLP-RLLPPGPPPGRPPGPPPGPPPGLPP 480
                 L P P P  PP   FL  P  PGL    P + L P       P  PP P  G   
Sbjct: 1802 -----LAPSPVPTLPPKQQFL--PSSPGLVLESPSKPLAPADEDELLPLIPPEPISG--- 1851

Query: 481  GPPPRGPPPRLPPPAPPGIPPPRPGMMRP 509
            G P +     +P P   GIP P P   +P
Sbjct: 1852 GVPFQSVLVNMPTPKSAGIPVPTPSAKQP 1880



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 21/76 (27%), Positives = 31/76 (40%), Gaps = 11/76 (14%)

Query: 138  SIPLP-DMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPR---L 193
            +IP P + P  PS+          + PP++   T    P  + + I P +    P+    
Sbjct: 1563 AIPTPKEAPATPSS-------KEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPT 1615

Query: 194  PPGRKPPGPPPGPPPP 209
            PP   PP P  GP  P
Sbjct: 1616 PPAVTPPSPEKGPATP 1631



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 20/53 (37%), Positives = 22/53 (41%), Gaps = 4/53 (7%)

Query: 159  PGAQPPSI---LKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPP 208
            P A PPS    L   S  G PT   +  P    G P  PP +  P PP   PP
Sbjct: 1221 PAATPPSPKGGLATPSPKGAPTTPAATPPS-PKGGPATPPPKGAPTPPAATPP 1272


>gi|73808090 zinc finger protein 207 isoform b [Homo sapiens]
          Length = 463

 Score = 97.8 bits (242), Expect = 3e-20
 Identities = 79/240 (32%), Positives = 105/240 (43%), Gaps = 37/240 (15%)

Query: 365 EAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPP 424
           E++K+ Q+   +E   D ++ ++S Q   PQ V P Q   PPM   P L P P  P  PP
Sbjct: 103 ESQKKKQQDDSDEYDDDDSAASTSFQ---PQPVQPQQGYIPPM-AQPGLPPVPGAPGMPP 158

Query: 425 GPPTGLPPGPP--PGAPPFLRPPGMP----------------GLRGPLPRLLPPGP---- 462
           G P  +P  PP  PG PP +  PGMP                 +  P+  ++PPGP    
Sbjct: 159 GIPPLMPGVPPLMPGMPPVM--PGMPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPP 216

Query: 463 -PPGRPPG-PPPGPPPGLPP---GPPPRGPPPRLPPPAPPG-IPPPRPGMMRPPLVPPLG 516
             PG PPG PPP P PG+PP         P     PPAP   +P P+P + + PL P  G
Sbjct: 217 LMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTK-PLFPSAG 275

Query: 517 PAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSAATIEKKATATISAKPQITNPKAEIT 576
            A   +  P       + S P    + PK   T  A  +  A+ T +       P A IT
Sbjct: 276 QAQAAVQGPVGTDFKPLNSTPATTTEPPK--PTFPAYTQSTASTTSTTNSTAAKPAASIT 333



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 45/139 (32%), Positives = 62/139 (44%), Gaps = 31/139 (22%)

Query: 383 TSTASSQQQAPPQSVPPSQIQAP--------PMPGPPPLGPPPAPPLRPPGPPTGLPPGP 434
           T++A+S+   P + +   + +A         P PG  P+G PP  P+    PP       
Sbjct: 341 TTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQ------ 394

Query: 435 PPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPP 494
                     PG+P  +G    + PP PP G+  G   G P  LP   PP G  P + PP
Sbjct: 395 ----------PGIPQQQG----MRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPP 440

Query: 495 APPGIPPPRPGM-MRPPLV 512
              G  PPRP M MRPP++
Sbjct: 441 YQGG--PPRPPMGMRPPVM 457



 Score = 34.3 bits (77), Expect = 0.36
 Identities = 30/108 (27%), Positives = 44/108 (40%), Gaps = 7/108 (6%)

Query: 111 EVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPD----MPHAPSNILIQDIPLPGAQPPSI 166
           ++  E++RAQL +Y   +       + + P+      MP  P     Q +  P   PP  
Sbjct: 354 DISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPP--MPPHG 411

Query: 167 LKKTSAYGPPTRAVSILPLLGHGVPRLPPGR-KPPGPPPGPPPPQVVQ 213
                  G P      +P  G G P +PP +  PP PP G  PP + Q
Sbjct: 412 QYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQ 459



 Score = 30.8 bits (68), Expect = 4.0
 Identities = 20/53 (37%), Positives = 24/53 (45%), Gaps = 18/53 (33%)

Query: 156 IPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPP 208
           +P+ G  PP         GP      I PL+    P +PPG  PP P PG PP
Sbjct: 202 MPMGGMMPP---------GP-----GIPPLM----PGMPPGMPPPVPRPGIPP 236



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 12/81 (14%)

Query: 140 PLPDMPHAPSNI--LIQDIP--LPGAQP-----PSILKKTSAYGPPTRAVSILPLLGHGV 190
           P+P  P  P  I  L+  +P  +PG  P     P  L     Y       +I+  +G  +
Sbjct: 149 PVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGLHHQRKYTQSFCGENIMMPMGGMM 208

Query: 191 PRLPPGRKP--PGPPPGPPPP 209
           P   PG  P  PG PPG PPP
Sbjct: 209 PP-GPGIPPLMPGMPPGMPPP 228


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score = 96.7 bits (239), Expect = 6e-20
 Identities = 89/283 (31%), Positives = 104/283 (36%), Gaps = 76/283 (26%)

Query: 332 AMMLRMAGQEIPEEGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQ 391
           A++   + Q + E+  + E  S    + +    +   Q Q+        +G       Q 
Sbjct: 9   ALLALSSAQSLNEDVSQEESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQS 68

Query: 392 APPQSVPPSQIQAPPMPGPPPLGPPPAP----------------PLRPPGPPTGLPP--- 432
             P   P      PP  G    GPPP P                P   PG P G PP   
Sbjct: 69  QGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGG 128

Query: 433 ----GPP--PGAPPFLRPPGMPGLRGPLPRL-LPPGPP-------------PGRPPGPPP 472
               GPP  PG P    P G    +GP PR   P GPP             PG+P GPPP
Sbjct: 129 NQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPP 188

Query: 473 -------GPP--PGLPPGPPP------RGPPPRL----------------PPPAP--PGI 499
                  GPP  PG P GPPP      +GPPPR                 PPP P  P  
Sbjct: 189 QGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQG 248

Query: 500 PPPRPG---MMRPPLVPPLGPAPPGLFPPAPLPNP-GVLSAPP 538
           PPP+ G      PP   P GP PPG  P  PLP P G    PP
Sbjct: 249 PPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPP 291



 Score = 96.7 bits (239), Expect = 6e-20
 Identities = 70/180 (38%), Positives = 78/180 (43%), Gaps = 24/180 (13%)

Query: 378 SHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPT--GLPPGPP 435
           + S G      + + PP          PP PG P  GPPP    +  GPP   G P GPP
Sbjct: 129 NQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPE-GPPPQGGNQSQGPPPHPGKPEGPP 187

Query: 436 P-GAPPFLRPPGMPGL-RGPLPR----LLPPGPPPGRPPGPP---------PGPPPGLPP 480
           P G      PP  PG   GP P+       P P PG+P GPP         P P PG P 
Sbjct: 188 PQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQ 247

Query: 481 GPPPR--GPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPP 538
           GPPP+    P R PPP  P  PPP  G  + PL PP G  P G   P P P  G    PP
Sbjct: 248 GPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAG-KPQG---PPPPPQGGRPHRPP 303



 Score = 91.7 bits (226), Expect = 2e-18
 Identities = 68/163 (41%), Positives = 76/163 (46%), Gaps = 35/163 (21%)

Query: 388 SQQQAPP------QSVPP---SQIQAPPMPGPPPLGPPPAPPLRPPGPPT--GLPPGPPP 436
           +Q Q PP      +  PP   +Q Q PP     P GPPP    +  GPP   G P GPPP
Sbjct: 150 NQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPP 209

Query: 437 -------GAPPFL-RPPGMPGLRGPLPRLLPPGPPPGRPPGPPPG--------PPPGLPP 480
                  G PP   +P G P   G  P+   P P PG+P GPPP         PPPG P 
Sbjct: 210 QGGNQSQGPPPRPGKPEGPPSQGGNKPQ--GPPPHPGKPQGPPPQEGNKPQRPPPPGRPQ 267

Query: 481 GPPPRGPPPR--LPPPA--PPGIPPPRPGMMRPPLVPPLGPAP 519
           GPPP G  P+  LPPPA  P G PPP  G    P  PP G  P
Sbjct: 268 GPPPPGGNPQQPLPPPAGKPQGPPPPPQG--GRPHRPPQGQPP 308



 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 76/230 (33%), Positives = 87/230 (37%), Gaps = 38/230 (16%)

Query: 343 PEEGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQI 402
           P+ G + +       + +    +   QSQ         +G       Q   P   P    
Sbjct: 41  PQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPE 100

Query: 403 QAPPMPGPPPLGPPPAPPLRPPGPPT-----GLPPGPPPGAPPFLRPPGMPGLRGPLPRL 457
             PP  G    GPPP P  +P GPP         P P PG P    P G    +GP PR 
Sbjct: 101 GQPPQGGNQSQGPPPRPG-KPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPR- 158

Query: 458 LPPGPPPGRPP-------GPPPGP--PPGLPP-------GPPPR-GPPPRLPPPA--PPG 498
             PG P G PP       GPPP P  P G PP       GPPPR G P   PP       
Sbjct: 159 --PGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQ 216

Query: 499 IPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPP----NLIQRP 544
            PPPRPG    P      P+  G  P  P P+PG    PP    N  QRP
Sbjct: 217 GPPPRPGKPEGP------PSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRP 260



 Score = 83.6 bits (205), Expect = 5e-16
 Identities = 60/173 (34%), Positives = 73/173 (42%), Gaps = 15/173 (8%)

Query: 343 PEEGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQI 402
           P+ G + +       + +    +   QSQ         +G       Q   P   P    
Sbjct: 146 PQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPE 205

Query: 403 QAPPMPGPPPLGPPPAPPLRPPGPPT---GLPPGPPPGAPPFLRPPGMPGLRGPLPRLLP 459
             PP  G    GPPP P  +P GPP+     P GPPP      +P G P   G  P+   
Sbjct: 206 GPPPQGGNQSQGPPPRPG-KPEGPPSQGGNKPQGPPPHPG---KPQGPPPQEGNKPQ--- 258

Query: 460 PGPPPGRPPGPPPGPPPGLP--PGPPPRGPPPRLPPPAPPGIPPPRPGMMRPP 510
             PPPGRP GPP  PP G P  P PPP G  P+ PPP P G  P RP   +PP
Sbjct: 259 RPPPPGRPQGPP--PPGGNPQQPLPPPAG-KPQGPPPPPQGGRPHRPPQGQPP 308



 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 51/152 (33%), Positives = 63/152 (41%), Gaps = 13/152 (8%)

Query: 343 PEEGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQI 402
           P+ G + +       + +    +   QSQ         +G       Q   P   P    
Sbjct: 167 PQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPE 226

Query: 403 QAPPMPGPPPLGPPPAPPLRPPGPP--TGLPP--GPPPGAPPFLRPPGMPGLRGPLPRLL 458
             P   G  P GPPP P  +P GPP   G  P   PPPG P    PPG    + PLP   
Sbjct: 227 GPPSQGGNKPQGPPPHPG-KPQGPPPQEGNKPQRPPPPGRPQGPPPPG-GNPQQPLP--- 281

Query: 459 PPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPR 490
              PP G+P GPPP PP G  P  PP+G PP+
Sbjct: 282 ---PPAGKPQGPPP-PPQGGRPHRPPQGQPPQ 309



 Score = 32.0 bits (71), Expect = 1.8
 Identities = 24/63 (38%), Positives = 26/63 (41%), Gaps = 18/63 (28%)

Query: 157 PLPGA-QPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPP---GRKPPGPPPGP-----P 207
           P PG  + P       + GPP R          G P  PP   G KP GPPP P     P
Sbjct: 199 PRPGKPEGPPPQGGNQSQGPPPRP---------GKPEGPPSQGGNKPQGPPPHPGKPQGP 249

Query: 208 PPQ 210
           PPQ
Sbjct: 250 PPQ 252



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 26/70 (37%), Positives = 29/70 (41%), Gaps = 17/70 (24%)

Query: 140 PLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKP 199
           P P  P  P +   Q    P   PP   K     GPP       P  G+  P+ PP   P
Sbjct: 220 PRPGKPEGPPS---QGGNKPQGPPPHPGKPQ---GPP-------PQEGNK-PQRPP---P 262

Query: 200 PGPPPGPPPP 209
           PG P GPPPP
Sbjct: 263 PGRPQGPPPP 272



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 22/59 (37%), Positives = 23/59 (38%), Gaps = 7/59 (11%)

Query: 159 PGAQPPSILKKTSAYGPPTRAVSILPLLGHGV-PRLPPGRKPPGPPPGPP------PPQ 210
           P   PP    K     PP R     P  G+   P  PP  KP GPPP P       PPQ
Sbjct: 246 PQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQ 304


>gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo
           sapiens]
          Length = 406

 Score = 96.7 bits (239), Expect = 6e-20
 Identities = 61/142 (42%), Positives = 68/142 (47%), Gaps = 10/142 (7%)

Query: 394 PQSVPPSQIQAPPMPGPPPLGP-PPAPPLRPPGPPTGLPPG----PPPGAPPFLRPPGMP 448
           PQ   P  +  PPMP  PP+ P PP PP+ P  P   +PPG    P P  P     P  P
Sbjct: 239 PQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWP 298

Query: 449 GLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIP-PPRPGMM 507
            +  P+P   P  P P  PP  P   PPG P    P GPP    PP PP  P PP P M 
Sbjct: 299 PM-APVPPWPPMAPVPTGPPMAP--VPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMA 355

Query: 508 RPPLVPPLGPAPPGLFPPAPLP 529
             P  PP+ P PPG  P APLP
Sbjct: 356 PLPPGPPMAPLPPGP-PMAPLP 376



 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 63/139 (45%), Positives = 68/139 (48%), Gaps = 18/139 (12%)

Query: 405 PPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPP 464
           P +P PP L  PP PP RPP  P  +PP PP    P + P   PG R      + P PP 
Sbjct: 239 PQLPRPPVLPVPPMPP-RPPMVP--MPPRPPIAPMPPMAPVP-PGSR------MAPVPPG 288

Query: 465 GRPPGPPPGPPPGLPPGPPPRGPPPRLPP--PAPPGIP----PPRPGMMRPPLVPPLGPA 518
            R    PP PP    P  PP  P P  PP  P PPG P    PP P M R P  PP+ P 
Sbjct: 289 PRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPL 348

Query: 519 PPGLFPPAPLPNPGVLSAP 537
           PPG  P APLP PG   AP
Sbjct: 349 PPGP-PMAPLP-PGPPMAP 365



 Score = 86.3 bits (212), Expect = 8e-17
 Identities = 57/139 (41%), Positives = 62/139 (44%), Gaps = 18/139 (12%)

Query: 393 PPQSVPPSQIQAPPMPG---PPPLGP----------PPAPPLR--PPGPPTGLPPGPPPG 437
           PP    P  +  PP P     PP+ P          PP P +   PP PP    P  PP 
Sbjct: 250 PPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPM 309

Query: 438 APPFLRPPGMPGLRGPLPRLLPPGPPPGR-PPGPPPGP-PPGLPPGPPPRGPPPRLPPPA 495
           AP    PP  P   GP    +PPGPP  R PPGPP  P PPG P  P P GPP    PP 
Sbjct: 310 APVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPG 369

Query: 496 PPGIP-PPRPGMMRPPLVP 513
           PP  P PPR  +    L P
Sbjct: 370 PPMAPLPPRSHVPHTGLAP 388



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 38/90 (42%), Positives = 44/90 (48%), Gaps = 12/90 (13%)

Query: 453 PLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLP-PPAPPGIP-PPRPGMMRPP 510
           P P +LP  P P RPP  P      +PP PP    PP  P PP     P PP P M   P
Sbjct: 242 PRPPVLPVPPMPPRPPMVP------MPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVP 295

Query: 511 LVPPLGPAPPGLFPP-APLP-NPGVLSAPP 538
             PP+ P PP  +PP AP+P  P +   PP
Sbjct: 296 PWPPMAPVPP--WPPMAPVPTGPPMAPVPP 323



 Score = 33.9 bits (76), Expect = 0.47
 Identities = 25/93 (26%), Positives = 35/93 (37%), Gaps = 7/93 (7%)

Query: 343 PEEGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQI 402
           PE G E E     +    SDD + E     + +++      +    QQ+ PP      + 
Sbjct: 51  PEYGTEAENNVGTEGSVPSDDQDREGGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQ 110

Query: 403 QAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPP 435
           + PP       GP PA      GP T   P PP
Sbjct: 111 EEPPQTTVE--GPQPA-----EGPQTAEGPQPP 136



 Score = 33.9 bits (76), Expect = 0.47
 Identities = 25/83 (30%), Positives = 30/83 (36%), Gaps = 14/83 (16%)

Query: 140 PLPDMPHAPSNILIQDIPLPGAQ-------------PPSILKKTSAYGPPTRAVSILPLL 186
           P+P M   P    +  +P PG +             PP         GPP   V   P +
Sbjct: 269 PMPPMAPVPPGSRMAPVP-PGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPM 327

Query: 187 GHGVPRLPPGRKPPGPPPGPPPP 209
               P  P  R PPGPP  P PP
Sbjct: 328 ARVPPGPPMARVPPGPPMAPLPP 350



 Score = 31.6 bits (70), Expect = 2.4
 Identities = 20/71 (28%), Positives = 26/71 (36%)

Query: 140 PLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKP 199
           P+  +P  P    +   P     PP         GPP   +   P +    P  P    P
Sbjct: 308 PMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLP 367

Query: 200 PGPPPGPPPPQ 210
           PGPP  P PP+
Sbjct: 368 PGPPMAPLPPR 378



 Score = 31.2 bits (69), Expect = 3.1
 Identities = 21/70 (30%), Positives = 25/70 (35%)

Query: 140 PLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKP 199
           P+  +P  P    +   P     PP         GPP   V   P +    P  P    P
Sbjct: 299 PMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLP 358

Query: 200 PGPPPGPPPP 209
           PGPP  P PP
Sbjct: 359 PGPPMAPLPP 368



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 36/160 (22%), Positives = 59/160 (36%), Gaps = 27/160 (16%)

Query: 67  PVQQPQLNEKVLKDKRKKLRETFERILRLYEKEN-------PDIYKELR----------K 109
           P + PQ  E     +RK+ R T     +L E EN       PD+    R          +
Sbjct: 123 PAEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDR 182

Query: 110 LEVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDIPLPGAQPPSILKK 169
           ++V ++ +RA+        +N + + + +    D+ H     L        A  P++   
Sbjct: 183 VQVWFQNRRAKWK------RNQRVLMLRNTATADLAHPLDMFLGGAYYAAPALDPALCVH 236

Query: 170 TSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPPP 209
                P    + + P+     PR P    PP PP  P PP
Sbjct: 237 LVPQLPRPPVLPVPPM----PPRPPMVPMPPRPPIAPMPP 272



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 22/77 (28%), Positives = 27/77 (35%), Gaps = 6/77 (7%)

Query: 139 IPLPDMPHAPSNIL------IQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPR 192
           +P+P MP  P  +       I  +P     PP         GP    V   P +    P 
Sbjct: 247 LPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPW 306

Query: 193 LPPGRKPPGPPPGPPPP 209
            P    P GPP  P PP
Sbjct: 307 PPMAPVPTGPPMAPVPP 323


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 96.7 bits (239), Expect = 6e-20
 Identities = 68/179 (37%), Positives = 77/179 (43%), Gaps = 30/179 (16%)

Query: 378  SHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPG 437
            S  +  S A ++      S   S +  PP+ GP     P  PPL P        PGPPP 
Sbjct: 1381 SSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAP----AAAVPGPPP- 1435

Query: 438  APPFLRPPGMPGLRG---PLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPP 494
                   PG+P       P P LL   PPP  PP P P P P  PP PPP  P P LP P
Sbjct: 1436 ------LPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQP--PPPPPP--PQPALPSP 1485

Query: 495  AP-----PGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADD 548
             P     P  PPP P    PP  PP  P+PP   PPA  P    L+APP     P  +D
Sbjct: 1486 PPLVAPTPSSPPPPP---LPPPPPPAMPSPPPPPPPAAAP----LAAPPEEPAAPSPED 1537



 Score = 85.9 bits (211), Expect = 1e-16
 Identities = 65/168 (38%), Positives = 73/168 (43%), Gaps = 15/168 (8%)

Query: 360  DSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQ--SVP--PSQIQAPPMPGPPPL-G 414
            D +DS A+ +      +ES S   S       A P+  S P  P    A  +PGPPPL G
Sbjct: 1383 DEEDSVAKNRDL----QESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPG 1438

Query: 415  PPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGP 474
             P A     P PP  L   PPP  PP   P   P    P P+   P PPP   P P   P
Sbjct: 1439 LPSANSNGTPEPPL-LEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPP 1497

Query: 475  PPGLPPGPPPRGPPPRLPPP---APPGIPPPRPGMMRP--PLVPPLGP 517
            PP LPP PPP  P P  PPP   AP   PP  P    P  P +P   P
Sbjct: 1498 PPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRP 1545



 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 94/389 (24%), Positives = 129/389 (33%), Gaps = 52/389 (13%)

Query: 140  PLPDMPHAPSN-----ILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLP 194
            PLP +P A SN      L+++ P P   PP+    T    PP       P L    P + 
Sbjct: 1435 PLPGLPSANSNGTPEPPLLEEKP-PPTPPPA---PTPQPQPPPPPPPPQPALPSPPPLVA 1490

Query: 195  PGRKPPGPPPGPPPPQVVQMYGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDVSSTSE 254
            P    P PPP PPPP            +   PP      +   PE       +  + + E
Sbjct: 1491 PTPSSPPPPPLPPPPPPAMP-------SPPPPPPPAAAPLAAPPE-------EPAAPSPE 1536

Query: 255  DDGYPEDMD---QDKHDDSTDDSDTDKSDGESDGDEFVHRDNGERDNNEEKKSGLSVRFA 311
            D   P+        K + +    +TD+  GES G E + R+  E     E    L +   
Sbjct: 1537 DPELPDTRPLHLAKKQETAAVCGETDEEAGESGG-EGIFRERDEFVIRAEDIPSLKLALQ 1595

Query: 312  ---DMPGKSRKKKKNMKELTP----------LQAMMLRMAGQEIPEEGREVEEFSEDDDE 358
               + P   R +K  +++ TP            +  L   G       R   +F E+ ++
Sbjct: 1596 TGREPPPIWRVQKALLQKFTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNK 1655

Query: 359  DDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPA 418
             D     A K          H        S Q   P S   S    P  P PPP    P 
Sbjct: 1656 KDYVRVCARKPW--------HRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPE 1707

Query: 419  PPL--RPP--GPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGP 474
                 +PP   P T +P  P P  P  LRP      +  + R   P        G    P
Sbjct: 1708 KTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRP 1767

Query: 475  PPGLPPGPPPRGPPPRLPPPAPPGIPPPR 503
               L  G P     P+  P      PPP+
Sbjct: 1768 ERSLATGQPATSRLPKARPTKVKAEPPPK 1796



 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 33/92 (35%), Positives = 37/92 (40%), Gaps = 3/92 (3%)

Query: 398  PPSQIQAPPMPGPPPLGPPPAPPLRP--PGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLP 455
            PP     P     PP GPP   P  P  PG  +G  P  P       +PP +P      P
Sbjct: 967  PPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEP 1026

Query: 456  R-LLPPGPPPGRPPGPPPGPPPGLPPGPPPRG 486
              L+  GP    PP PPP PPP  P   P  G
Sbjct: 1027 LGLIQSGPHQAAPPPPPPPPPPPAPASEPKGG 1058



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 47/144 (32%), Positives = 54/144 (37%), Gaps = 33/144 (22%)

Query: 410 PPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPG---MPGLRGPLP----------- 455
           PPP  PPP      P P   L     P  P  L PP    +P +    P           
Sbjct: 764 PPP--PPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGV 821

Query: 456 RLLPPGPPPG--RPPGPPPGPPPGLP---------PGPPPRGPPPRLPPPA---PPGIPP 501
            LL P    G  +PP PPP PPP +P          G  P  P PRL P     PPG   
Sbjct: 822 HLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQ 881

Query: 502 PRPGMMRPPLVPPLGPAPPGLFPP 525
              G + P  +PP  P   G+ PP
Sbjct: 882 ELLGALEP--LPP-APGDTGVGPP 902



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 37/103 (35%), Positives = 40/103 (38%), Gaps = 8/103 (7%)

Query: 409  GPPP-LGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRP 467
            GPP   G P A    PPGPP   P GP          P  PGL       L P  PP  P
Sbjct: 966  GPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLG------LDPNKPPELP 1019

Query: 468  PGPPPGPPPGLPPGPPPRGPPPRLPPPAPPG-IPPPRPGMMRP 509
                  P   +  GP    PPP  PPP PP     P+ G+  P
Sbjct: 1020 STVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSP 1062



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 56/174 (32%), Positives = 62/174 (35%), Gaps = 26/174 (14%)

Query: 423 PPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPP--GPPPGPPPGLPP 480
           PP PPT     P P     L   G P L    P +LPP PP   P      P P P    
Sbjct: 765 PPPPPTAQSTQPTPHG--LLLEAGGPDL----PLVLPPPPPQLLPSVLSHAPSPSPSASK 818

Query: 481 ------GPPPRGPPPRLPPPAPPGIPPPRPGMMRPPL----VPPLGPAPPGLFPPAPLPN 530
                  P  R   P+ PPP PP  PPP P  +   L    + P  P+ P L P   L  
Sbjct: 819 VGVHLLEPATRDGAPQ-PPPPPPPPPPPMPLQLEAHLRSHGLEPAAPS-PRLRPEESLDP 876

Query: 531 PG----VLSAPPNLIQRPKADDTSAATIEKKATATISAKPQITNPKAEITRFVP 580
           PG    +L A   L   P          E K  A     P     KA   RFVP
Sbjct: 877 PGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKA--PRFVP 928



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 29/91 (31%), Positives = 36/91 (39%), Gaps = 6/91 (6%)

Query: 393  PPQSVPPSQIQAPPMPGPP------PLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPG 446
            PP+     +  A P PGPP      P  P  A    P  P  GL P  PP  P  +    
Sbjct: 967  PPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEP 1026

Query: 447  MPGLRGPLPRLLPPGPPPGRPPGPPPGPPPG 477
            +  ++    +  PP PPP  PP  P   P G
Sbjct: 1027 LGLIQSGPHQAAPPPPPPPPPPPAPASEPKG 1057



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 59/210 (28%), Positives = 73/210 (34%), Gaps = 52/210 (24%)

Query: 386  ASSQQQAPPQSV-PPSQIQA--------PPMPGPPPLGPP------PAPPLRPPGP---- 426
            A S +  P +S+ PP  +Q         PP PG   +GPP      PA   R P P    
Sbjct: 863  APSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTK 922

Query: 427  ------------PTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPP---GPPP---GRPP 468
                        P  L         P +      G      +  PP   G P    G PP
Sbjct: 923  APRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPP 982

Query: 469  GPP---------PGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRP---PLVPPLG 516
            GPP         PG   G  P  P  G  P  PP  P  +     G+++       PP  
Sbjct: 983  GPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPP 1042

Query: 517  PAPPGLFPPAPLPNP-GVLSAPPNLIQRPK 545
            P PP   PPAP   P G L++P     +PK
Sbjct: 1043 PPPPP--PPAPASEPKGGLTSPIFCSTKPK 1070



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 42/122 (34%), Positives = 48/122 (39%), Gaps = 8/122 (6%)

Query: 380 SDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPG--PPTGL-PPGPPP 436
           S   S + S  +     + P+     P P PPP  PPP  PL+        GL P  P P
Sbjct: 807 SHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSP 866

Query: 437 GAPP--FLRPPG-MPGLRGPLPRLLP-PGPPPGRPPGPPPGPPPGLPPGPPPRG-PPPRL 491
              P   L PPG M  L G L  L P PG     PP      P G    P P+G   PR 
Sbjct: 867 RLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRF 926

Query: 492 PP 493
            P
Sbjct: 927 VP 928



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 38/118 (32%), Positives = 42/118 (35%), Gaps = 14/118 (11%)

Query: 388 SQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGM 447
           SQ    P S+   ++    + GP  LGP   PP R PGPP   PP PP   P        
Sbjct: 194 SQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYR-PGPPD--PPPPPRHLPTQFNLLAS 250

Query: 448 PGLRGPLPRLLPPG--PPPGRPPGPPPGPPPGLPPGP--------PPRGPPPRLPPPA 495
                       P      G  PGPPP P   LP           P    PP  PPPA
Sbjct: 251 SSAAAAAAEQSSPQLYNFSGAAPGPPP-PERALPRQDTVIKHYQRPASAQPPPPPPPA 307



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 47/159 (29%), Positives = 53/159 (33%), Gaps = 35/159 (22%)

Query: 399 PSQIQAPPMPGPPPLG---PPPAPP---LRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRG 452
           P+   + P P P  L    PP +PP   L  P     L P   P  P  L   G   L G
Sbjct: 154 PASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSL---GFERLAG 210

Query: 453 PLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLP-------------------- 492
               L P G  P + P   PGPP    P PPPR  P +                      
Sbjct: 211 G-GVLGPAGLGPAQTPPYRPGPPD---PPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLY 266

Query: 493 --PPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLP 529
               A PG PPP   + R   V      P    PP P P
Sbjct: 267 NFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPP 305



 Score = 38.9 bits (89), Expect = 0.015
 Identities = 17/35 (48%), Positives = 20/35 (57%), Gaps = 2/35 (5%)

Query: 470  PPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRP 504
            PP  PP  +PP  P RG  P+  PPA P +P P P
Sbjct: 1305 PPLSPPKSVPPSVPARGLQPQ--PPATPAVPHPPP 1337



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 39/127 (30%), Positives = 56/127 (44%), Gaps = 25/127 (19%)

Query: 136 VESIPLPDMPHA------PSNILIQ----DIPLP-GAQPPSILKKTSAYGP-PTRAVSIL 183
           ++  P P  P A      P  +L++    D+PL     PP +L    ++ P P+ + S +
Sbjct: 760 LQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKV 819

Query: 184 PLLGHGVPRLPPGRK-----PPGPPPGPPPPQVVQM--YGRKVGFALDLP-PRRRDEDML 235
                GV  L P  +     PP PPP PPPP  +Q+  + R  G     P PR R E+ L
Sbjct: 820 -----GVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESL 874

Query: 236 YSPELAQ 242
             P   Q
Sbjct: 875 DPPGAMQ 881



 Score = 36.6 bits (83), Expect = 0.073
 Identities = 32/108 (29%), Positives = 39/108 (36%), Gaps = 32/108 (29%)

Query: 470 PPPGPPPGLPPGPPPRG----------------PPPRL--------PPPAPPGI------ 499
           PPP PP      P P G                PPP+L        P P+P         
Sbjct: 764 PPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHL 823

Query: 500 --PPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPK 545
             P  R G  +PP  PP  P P  L   A L + G+  A P+   RP+
Sbjct: 824 LEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPE 871



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 23/72 (31%), Positives = 29/72 (40%), Gaps = 2/72 (2%)

Query: 440  PFLRPPGMPGLRGPLPRLLPPGPPPGRPP-GPPPGPPPGLPPGPPPRGPPPRLPPPAPPG 498
            P+ RPP      G     +  G     PP  P P P P  P       PP + P  A P 
Sbjct: 1666 PWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPE 1725

Query: 499  IP-PPRPGMMRP 509
             P P +P ++RP
Sbjct: 1726 PPAPEKPSLLRP 1737



 Score = 33.9 bits (76), Expect = 0.47
 Identities = 47/160 (29%), Positives = 54/160 (33%), Gaps = 22/160 (13%)

Query: 383 TSTASSQQQAPPQSVPPSQIQA--PPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPP 440
           T  AS    A  Q+  P Q Q    P       G   A  L      +G PP PP G P 
Sbjct: 429 TGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPP- 487

Query: 441 FLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGP---PPGLPPGPP----PRGPPPRL-- 491
              PPG+   +   P  L  G   G    P PGP     GLP   P      G  P L  
Sbjct: 488 ---PPGLATCQSYSPDQL-QGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSG 543

Query: 492 ------PPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPP 525
                 P     G       ++RP   PP    PPG+  P
Sbjct: 544 HGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSP 583



 Score = 33.5 bits (75), Expect = 0.62
 Identities = 35/126 (27%), Positives = 43/126 (34%), Gaps = 10/126 (7%)

Query: 379 HSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGA 438
           H+ G +        P  S  PS         P   G  P P       P+ L    PP +
Sbjct: 123 HTPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFPV------PSSLSLQDPPFS 176

Query: 439 PP---FLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGP-PPRGPPPRLPPP 494
           PP    L P  +  L+      +P      R  G     P GL P   PP  P P  PPP
Sbjct: 177 PPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPP 236

Query: 495 APPGIP 500
            P  +P
Sbjct: 237 PPRHLP 242



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 42/139 (30%), Positives = 46/139 (33%), Gaps = 15/139 (10%)

Query: 391 QAPPQSVPPSQIQAPPMP--GPPPLGPPPAPPLRPP---GPPTGLPPGPPPGAPPFLR-- 443
           QA   S  PS    PP P  GPPP G        P    G   G+   P PG     +  
Sbjct: 465 QAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGL 524

Query: 444 PPGMPGLR---GPLPRLLPPGP---PPGRPPGPPPGPPPGLPP--GPPPRGPPPRLPPPA 495
           P   P L    G  P L   G    P     G    P   + P   PP  G PP +  P 
Sbjct: 525 PTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPG 584

Query: 496 PPGIPPPRPGMMRPPLVPP 514
            PG          P L PP
Sbjct: 585 APGKYLSSVLASAPFLAPP 603



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 22/67 (32%), Positives = 24/67 (35%), Gaps = 3/67 (4%)

Query: 462  PPPGRPPGPPPGP-PPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAP- 519
            P P R  G    P   G    PPP+ P P   P  P      +P    P    P  PAP 
Sbjct: 1671 PVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPE 1730

Query: 520  -PGLFPP 525
             P L  P
Sbjct: 1731 KPSLLRP 1737



 Score = 31.6 bits (70), Expect = 2.4
 Identities = 27/87 (31%), Positives = 36/87 (41%), Gaps = 5/87 (5%)

Query: 383 TSTASSQQQAPPQSVPPSQIQAPPMPGPPP-LGPPPAPPLRPPGPPTGLPPGPPPGAPPF 441
           +S     + +P   + P  +Q+PP  G PP +G P AP           P   PPGA  +
Sbjct: 551 SSLGGGGEASPSHIIRP--LQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSY 608

Query: 442 LRPPGMPGLRGPLPRLL--PPGPPPGR 466
               G    +G    LL  P GPP  R
Sbjct: 609 AAGAGGYKGKGDGSELLAGPGGPPAER 635



 Score = 31.6 bits (70), Expect = 2.4
 Identities = 22/74 (29%), Positives = 30/74 (40%), Gaps = 7/74 (9%)

Query: 478 LPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPP----APLPNPGV 533
           L   PPP  P  +   P P G+     G   P ++P   P PP L P     AP P+P  
Sbjct: 760 LQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLP---PPPPQLLPSVLSHAPSPSPSA 816

Query: 534 LSAPPNLIQRPKAD 547
                +L++    D
Sbjct: 817 SKVGVHLLEPATRD 830



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 47/183 (25%), Positives = 58/183 (31%), Gaps = 33/183 (18%)

Query: 406 PMPGPPPLG-------PPPAPPLRPPGPPTGLPPGPPPGAPPF--------LRPPGMPGL 450
           P PGP           P     +  PGP      G  PG+  F         + P   G 
Sbjct: 100 PQPGPSASSLLSQFRSPSWQTAMHTPGPTELFISGALPGSSTFPSSSALSAYQHPASFGS 159

Query: 451 RG-PLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGP--PPRLPPPAPPGIPPPRPGMM 507
           R  P+P  L    PP  PP      P  +    P + P  P  L      G     P  +
Sbjct: 160 RPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGL 219

Query: 508 RPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSAATIEKKATATISAKPQ 567
            P   PP  P PP      P P P  L    NL+          A+    A A   + PQ
Sbjct: 220 GPAQTPPYRPGPPD-----PPPPPRHLPTQFNLL----------ASSSAAAAAAEQSSPQ 264

Query: 568 ITN 570
           + N
Sbjct: 265 LYN 267



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 138 SIPLPDMPHAP-SNILIQDIPLPGAQPPSILKKTSAYGPPTRAVS-ILPLLGHGVPRLPP 195
           S+ L D P +P +N L+    +   +P       S+ G    A   +L   G G  + PP
Sbjct: 167 SLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPP 226

Query: 196 GRKPPGPPPGPPPPQ 210
            R  PGPP  PPPP+
Sbjct: 227 YR--PGPPDPPPPPR 239



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 35/124 (28%), Positives = 43/124 (34%), Gaps = 12/124 (9%)

Query: 384 STASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRP------PGPPTGLPPGPPPG 437
           +++S+   A  QS P     +   PGPPP  P  A P +         P +  PP PPP 
Sbjct: 249 ASSSAAAAAAEQSSPQLYNFSGAAPGPPP--PERALPRQDTVIKHYQRPASAQPPPPPPP 306

Query: 438 A---PPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPP 494
           A     +L   G     G     L   P  G  P P  G P    P     G   R   P
Sbjct: 307 AHALQHYLSCGGSYPSMGHRAN-LACSPLGGGEPSPGAGEPSKAGPSGATAGASGRATGP 365

Query: 495 APPG 498
              G
Sbjct: 366 EAAG 369



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 21/81 (25%), Positives = 32/81 (39%), Gaps = 4/81 (4%)

Query: 487  PPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKA 546
            PPP+ P P P    P +    +PP   P    P    PPAP   P +L       ++ K 
Sbjct: 1692 PPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPE---PPAP-EKPSLLRPVEKEKEKEKV 1747

Query: 547  DDTSAATIEKKATATISAKPQ 567
                     ++AT+    +P+
Sbjct: 1748 TRGERPLRGERATSGRQTRPE 1768


>gi|72004269 tetra-peptide repeat homeobox [Homo sapiens]
          Length = 411

 Score = 95.5 bits (236), Expect = 1e-19
 Identities = 79/181 (43%), Positives = 86/181 (47%), Gaps = 30/181 (16%)

Query: 394 PQSVPPSQIQAPPMPGPPPLGPPPAPPLRP-PGPPTGLPPGPPPGAPPFLRPPGMPGLRG 452
           P S P S     P+PGP P GP P P   P PGP +   PGP PG  P   P   P   G
Sbjct: 166 PISGPFSGPNPGPIPGPNP-GPIPGPISGPIPGPISVPIPGPIPG--PISGPISGPN-PG 221

Query: 453 PLPRLLP---PGPPPGRPPGPPPGPPPGLPPGPPP---RGPPPRLPP-PAPPGIPPP--- 502
           P+P  +P    GP PG  PGP  GP PGL PGP P    GP P + P P+P  IP P   
Sbjct: 222 PIPGPIPGPISGPNPGPIPGPISGPNPGLIPGPIPGPISGPGPIIGPIPSPAQIPGPGRL 281

Query: 503 -------RPGMMRPP-----LVPPLGP--APPGLFPPAPLPNPGVLSAP-PNLIQRPKAD 547
                   PG MR P     L P LGP   P     PAP+P PG L AP P   Q P A 
Sbjct: 282 QGPGPILSPGRMRSPGSLPGLAPILGPGSGPGSGSVPAPIPGPGSLPAPAPLWPQSPDAS 341

Query: 548 D 548
           D
Sbjct: 342 D 342



 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 68/171 (39%), Positives = 82/171 (47%), Gaps = 27/171 (15%)

Query: 394 PQSVP-----PSQIQAP---PMPGP---------PPLGPPPAP---PLRPPGPPTGLPPG 433
           P S+P     P+QI +P   P+PGP         P  GP P P   P   PGP +G   G
Sbjct: 114 PGSIPGPIPGPAQIPSPIPAPIPGPISGPVQIPGPFRGPIPGPISGPAPIPGPISGPFSG 173

Query: 434 PPPGAPPFLRPPGMPG-LRGPLPRLLP---PGPPPGRPPGPPPGPPPGLPPGPPPRGPPP 489
           P PG  P   P  +PG + GP+P  +    PGP PG   GP  GP PG  PGP P     
Sbjct: 174 PNPGPIPGPNPGPIPGPISGPIPGPISVPIPGPIPGPISGPISGPNPGPIPGPIPGPISG 233

Query: 490 RLPPPAPPGIPPPRPGMMRPPLVPPL-GPAP-PGLFP-PAPLPNPGVLSAP 537
             P P P  I  P PG++  P+  P+ GP P  G  P PA +P PG L  P
Sbjct: 234 PNPGPIPGPISGPNPGLIPGPIPGPISGPGPIIGPIPSPAQIPGPGRLQGP 284



 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 67/167 (40%), Positives = 77/167 (46%), Gaps = 24/167 (14%)

Query: 402 IQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPG---------AP---PFLRPPGMPG 449
           I A   PGP P+  P   P + PGP  G  PGP PG         AP   P   P  +PG
Sbjct: 88  IPAALSPGPGPIPAPIPGPAQIPGPLPGSIPGPIPGPAQIPSPIPAPIPGPISGPVQIPG 147

Query: 450 -LRGPLPRLLP-----PGPPPGRPPGPPPGPPPGLPPGPPP---RGP-PPRLPPPAPPGI 499
             RGP+P  +      PGP  G   GP PGP PG  PGP P    GP P  +  P P  I
Sbjct: 148 PFRGPIPGPISGPAPIPGPISGPFSGPNPGPIPGPNPGPIPGPISGPIPGPISVPIPGPI 207

Query: 500 PPPRPGMMRPPLVPPL-GPAPPGLFPPAPLPNPGVLSAP-PNLIQRP 544
           P P  G +  P   P+ GP P  +  P P P PG +S P P LI  P
Sbjct: 208 PGPISGPISGPNPGPIPGPIPGPISGPNPGPIPGPISGPNPGLIPGP 254



 Score = 67.0 bits (162), Expect = 5e-11
 Identities = 55/156 (35%), Positives = 66/156 (42%), Gaps = 9/156 (5%)

Query: 391 QAPPQSVPPSQIQ----APPMPGPPPLGPPPAPP-LRPPGPPTGLPPGPPPGAPPFLRPP 445
           Q  PQ VP  + +    AP +P      P   P  + P   PT        G P      
Sbjct: 27  QQQPQRVPGQRGRGARAAPLVPAASASAPQRGPSGILPAAEPTICSLHQAWGGPGCRAQK 86

Query: 446 GMPGLRGPLPRLLP-PGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRP 504
           G+P    P P  +P P P P + PGP PG  PG  PGP     P   P P P   P   P
Sbjct: 87  GIPAALSPGPGPIPAPIPGPAQIPGPLPGSIPGPIPGPAQIPSPIPAPIPGPISGPVQIP 146

Query: 505 GMMRPPLVPPL-GPAP-PG-LFPPAPLPNPGVLSAP 537
           G  R P+  P+ GPAP PG +  P   PNPG +  P
Sbjct: 147 GPFRGPIPGPISGPAPIPGPISGPFSGPNPGPIPGP 182



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 49/138 (35%), Positives = 55/138 (39%), Gaps = 22/138 (15%)

Query: 399 PSQIQAP---PMPGP-----PPLGPPPAP-PLRPPGPPTGLPPGPP----PG---APPFL 442
           P  I  P   P+PGP     P L P P P P+  PGP  G  P P     PG    P  +
Sbjct: 228 PGPISGPNPGPIPGPISGPNPGLIPGPIPGPISGPGPIIGPIPSPAQIPGPGRLQGPGPI 287

Query: 443 RPPGMPGLRGPLPRLLP---PGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGI 499
             PG     G LP L P   PG  PG    P P P PG  P P P  P     P A   +
Sbjct: 288 LSPGRMRSPGSLPGLAPILGPGSGPGSGSVPAPIPGPGSLPAPAPLWPQ---SPDASDFL 344

Query: 500 PPPRPGMMRPPLVPPLGP 517
           P  +       L+ PL P
Sbjct: 345 PDTQLFPHFTELLLPLDP 362


>gi|18959210 WIRE protein [Homo sapiens]
          Length = 440

 Score = 95.5 bits (236), Expect = 1e-19
 Identities = 111/414 (26%), Positives = 138/414 (33%), Gaps = 112/414 (27%)

Query: 193 LPPGRKPPGPPPGPPPPQVVQMYGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDVSST 252
           +PP   PP PPPGPPPP              + P   RDE         QRG    +   
Sbjct: 3   IPP---PPPPPPGPPPPPTFHQANT------EQPKLSRDE---------QRGRGALLQDI 44

Query: 253 SEDDGYPEDMDQDKHDDSTDDSDTDKSDGESDGDEFVHRDNGERDNNEEKKSGLSVRFAD 312
            +     +  + +       +     S G   G   +    G       K          
Sbjct: 45  CKGTKLKKVTNINDRSAPILEKPKGSSGGYGSGGAALQPKGGLFQGGVLKLR-------- 96

Query: 313 MPGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREVEEFSEDDDEDDSDDSEAEKQSQK 372
            P  ++   +N+     LQ    R A    P         +    +DD+D S A      
Sbjct: 97  -PVGAKDGSENLAGKPALQIPSSRAAAPRPPVSA------ASGRPQDDTDSSRASLPELP 149

Query: 373 QHKEESHSDGT--STASS-----QQQAPPQSVPPSQIQAPPMPGP--------------- 410
           + +  S  D +  +T SS        APP   P  +  APP P P               
Sbjct: 150 RMQRPSLPDLSRPNTTSSTGMKHSSSAPPPPPPGRRANAPPTPLPMHSSKAPAYNREKPL 209

Query: 411 PPL----------GPPPAPPLRPPGPPTGLPPGPP-----PGAPPFLRPPGMP-GLRGPL 454
           PP           GPP  PP++PP  P  +  GP      P  PP+ +PPG+P G   P 
Sbjct: 210 PPTPGQRLHPGREGPPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPT 269

Query: 455 PRLLP-------------PGPPPGRPPGPPPGPPPGL---PPGPPPRGPPPR--LPPPAP 496
               P             PGP  G  P PP    P L    P PP R PP R   PPP P
Sbjct: 270 NESAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPPP 329

Query: 497 PGI--------PPPRPGMMR------------PPLVPPLGPAPPGLFPPAPLPN 530
           P I        PPP P  M             PP   P GP PP   PP PL N
Sbjct: 330 PVIRNGARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTPAGPPPP---PPPPLRN 380



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 37/92 (40%), Positives = 41/92 (44%), Gaps = 11/92 (11%)

Query: 393 PPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGP---PPGAPPFLRPPGMPG 449
           PP S  PS +   P   PPP   PP+    PP PP  +  G    PP  PP+      P 
Sbjct: 298 PPTSASPSLLSNRP---PPPARDPPSRGAAPPPPPPVIRNGARDAPPPPPPYRMHGSEPP 354

Query: 450 LRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPG 481
            RG      PP PP   P GPPP PPP L  G
Sbjct: 355 SRGK-----PPPPPSRTPAGPPPPPPPPLRNG 381



 Score = 38.9 bits (89), Expect = 0.015
 Identities = 27/86 (31%), Positives = 35/86 (40%), Gaps = 22/86 (25%)

Query: 142 PDMPHAPSNILIQDIPLPGAQ-----------PPSILKKTSAYGPPTRAVSILPLLGHGV 190
           P  P + S  L+ + P P A+           PP +++  +   PP       P   HG 
Sbjct: 296 PPPPTSASPSLLSNRPPPPARDPPSRGAAPPPPPPVIRNGARDAPPPPP----PYRMHGS 351

Query: 191 -------PRLPPGRKPPGPPPGPPPP 209
                  P  PP R P GPPP PPPP
Sbjct: 352 EPPSRGKPPPPPSRTPAGPPPPPPPP 377



 Score = 37.0 bits (84), Expect = 0.056
 Identities = 29/76 (38%), Positives = 36/76 (47%), Gaps = 8/76 (10%)

Query: 157 PLPGAQ---PPSILKKTSAYGPP-TRAVSILPLLGHGVPRLPPGRK-PPGPPPGPPPPQV 211
           P PG +   PP+ L   S+  P   R   + P  G    RL PGR+ PP PPP  PPP  
Sbjct: 180 PPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQ---RLHPGREGPPAPPPVKPPPSP 236

Query: 212 VQMYGRKVGFALDLPP 227
           V +     G +L  PP
Sbjct: 237 VNIRTGPSGQSLAPPP 252



 Score = 34.7 bits (78), Expect = 0.28
 Identities = 28/90 (31%), Positives = 37/90 (41%), Gaps = 11/90 (12%)

Query: 142 PDMPHAPSNILIQDIPLPGAQPPSILKKTSA----YGPPTRAVSILPLLGHGVPRLPPGR 197
           P +P+ PS+   +  P    +  S+ +KT        PP    +   LL +  P  PP R
Sbjct: 259 PGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLLSNRPP--PPAR 316

Query: 198 KPPGPPPGPPPPQVVQMYGRKVGFALDLPP 227
            PP     PPPP  V   G     A D PP
Sbjct: 317 DPPSRGAAPPPPPPVIRNG-----ARDAPP 341



 Score = 30.4 bits (67), Expect = 5.2
 Identities = 11/17 (64%), Positives = 12/17 (70%)

Query: 412 PLGPPPAPPLRPPGPPT 428
           P+ PPP PP  PP PPT
Sbjct: 2   PIPPPPPPPPGPPPPPT 18


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 116/480 (24%), Positives = 150/480 (31%), Gaps = 74/480 (15%)

Query: 197 RKPPGPPPGPPPPQVVQMY---GRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDVSSTS 253
           R   GP PG P P + +     G +VG     P  R        P     G    VSS S
Sbjct: 153 RDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR--------PRPPTEGPRKSVSSAS 204

Query: 254 EDDGYPEDMDQDKHDD-----------STDDSDTDKSDGESDGDEFVHRDNGERDNNEEK 302
           E           +              S   S T  S     G             ++ K
Sbjct: 205 EHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK 264

Query: 303 KSGLSVRFADMPGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREVEEFSEDDDEDDSD 362
             GL       P  +  +K     L PL +  L       P                 + 
Sbjct: 265 PKGLQA--LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATP 322

Query: 363 DSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPS----QIQAPPMP--GPP----- 411
            S+A         + +HS   S   S    PP   PP+     +QAPP P   PP     
Sbjct: 323 PSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLA 382

Query: 412 -----------------PLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPL 454
                            P  PPP+PP++ P  P   PP  P   PP   PP +       
Sbjct: 383 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL------- 435

Query: 455 PRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPR--PGMMRPPLV 512
                  PP   PP PP  PP      PPP+ PPP   PP     PPP+  P +  PPL 
Sbjct: 436 -----AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPL- 489

Query: 513 PPLGPAPPGLFP-PAPLPNPGVLSAPPNLIQRPKADDTSAATIEKKATATISAKPQITNP 571
               P+PP  FP  AP      L   P     P+A    AA +  +   +  A P +  P
Sbjct: 490 -QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL-LQVPPSPPASPTLQAP 547

Query: 572 KAEITRFVPTALRVRREN----KGATAAPQRKSEDDSAVPLAKAAPKSGPSVPVSVQTKD 627
           +   T    T++   R       G    P R      + P       S  S P  ++  D
Sbjct: 548 RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD 607



 Score = 66.6 bits (161), Expect = 7e-11
 Identities = 69/236 (29%), Positives = 75/236 (31%), Gaps = 82/236 (34%)

Query: 384 STASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPP-----APPLRPPG-----PPTGLPPG 433
           S     Q  PP + PP Q+  PP   PP L  PP     +PP   PG     P   LP  
Sbjct: 455 SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 514

Query: 434 P----PPGAPPFLR---------PPGMPGLRGPL-------------PRL---LPPGPPP 464
           P    PP APP L          PP  P L+ P              PRL   L PGPPP
Sbjct: 515 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 574

Query: 465 GRPPGPPP----------------------------GPPPGLPPGPPP------------ 484
             PP   P                            GP  G    PPP            
Sbjct: 575 --PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW 632

Query: 485 -RGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPN 539
            RGP P L     PG P P P    P     L        P +  P PG L   P+
Sbjct: 633 SRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPS 688



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 65/233 (27%), Positives = 76/233 (32%), Gaps = 36/233 (15%)

Query: 418 APPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRP-PGPPPGPPP 476
           AP L  P PP G P  PPP  P  LR  G  G  G  P     G   G   P   P   P
Sbjct: 21  APGLLTPRPP-GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGP 79

Query: 477 GLPPGPPPRGPPPRLPP-----PAPPGIPPPRPGMMRP-PL------------------- 511
                PP  G   R PP     P P   P    G  RP PL                   
Sbjct: 80  TRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKAT 139

Query: 512 -VPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSA-----ATIEKKATATISAK 565
             P       G       P PG  S  P + +R +A  T       A   +    T   +
Sbjct: 140 EAPKRSALSAGARRDTSGPTPGTPS--PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPR 197

Query: 566 PQITNPKAEITRFVPTALRVRRENKGATAAPQRKSEDDSAVPLAKAAPKSGPS 618
             +++     T     A R R    G    P  +S   SA PL+  A +SGPS
Sbjct: 198 KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA-RSGPS 249



 Score = 37.4 bits (85), Expect = 0.043
 Identities = 53/196 (27%), Positives = 68/196 (34%), Gaps = 26/196 (13%)

Query: 443 RPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPG---PPPRGPPPRLPPPAPPG- 498
           R     G     P    PG    RPPG P  PPP  P         G   R P     G 
Sbjct: 5   RDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGG 64

Query: 499 -----IP--PPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSA 551
                IP   PR G  R    P  G       PPA   +PG +S+P       +A  T+ 
Sbjct: 65  IGGATIPESAPRAGPTRTSRPPASGRGERA--PPAKNTSPGPVSSP------GRASGTTR 116

Query: 552 ATIEKKATATISAKPQITNPKA-EITRFVPTALRVRRENKGAT------AAPQRKSEDDS 604
                +    ISA+  +   KA E  +    +   RR+  G T      A  +R     +
Sbjct: 117 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 176

Query: 605 AVPLAKAAPKSGPSVP 620
            V L + AP + P  P
Sbjct: 177 EVGLPRPAPSARPRPP 192



 Score = 37.0 bits (84), Expect = 0.056
 Identities = 25/77 (32%), Positives = 34/77 (44%), Gaps = 13/77 (16%)

Query: 142 PDMPHAPSNILIQDIPLPGAQPPS---------ILKKTSAY--GPPTRAVSILPLLGHGV 190
           P  P AP ++  Q +P P A PPS          L+ T ++   PP   ++  P      
Sbjct: 303 PPSPSAPPSL--QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA 360

Query: 191 PRLPPGRKPPGPPPGPP 207
             LPP + PP PP  PP
Sbjct: 361 LALPPLQAPPSPPASPP 377



 Score = 35.0 bits (79), Expect = 0.21
 Identities = 34/129 (26%), Positives = 48/129 (37%), Gaps = 15/129 (11%)

Query: 140 PLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKP 199
           P P  P A +   +Q +P P A  P     + +   P   ++  P     V   P  + P
Sbjct: 476 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 535

Query: 200 PGPPPG---------PPPPQVVQMYGRKVGFAL----DLPPRRRDEDMLYSPELAQRGHD 246
           P PP           P P     + G ++  AL      PP R     L  P+LA  GH 
Sbjct: 536 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA--GHS 593

Query: 247 DDVSSTSED 255
              +ST E+
Sbjct: 594 SSATSTPEE 602



 Score = 35.0 bits (79), Expect = 0.21
 Identities = 36/127 (28%), Positives = 42/127 (33%), Gaps = 11/127 (8%)

Query: 383 TSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGL--PPGPPPGAPP 440
           ++T++ ++     S P     A P P        PA   R P PP      PG P   PP
Sbjct: 595 SATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPP 654

Query: 441 FLRPPGMPGL------RGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPP 494
              P    GL       GP      PG      PGP PG   G        G   R P  
Sbjct: 655 ATGPGSADGLCTIYETEGPESATPAPG---ALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 711

Query: 495 APPGIPP 501
           A  G  P
Sbjct: 712 ARLGELP 718



 Score = 33.9 bits (76), Expect = 0.47
 Identities = 32/106 (30%), Positives = 39/106 (36%), Gaps = 5/106 (4%)

Query: 364 SEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRP 423
           S A    ++    +S  +G + AS    A   +  P+     P P     G P AP   P
Sbjct: 594 SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP--LP 651

Query: 424 PGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPG 469
             P TG  PG   G        G P    P P  L PGP PG   G
Sbjct: 652 WPPATG--PGSADGLCTIYETEG-PESATPAPGALDPGPSPGTSGG 694



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 33/115 (28%), Positives = 41/115 (35%), Gaps = 11/115 (9%)

Query: 131 AQHVEVESIPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGV 190
           A  ++V   P    P +PS       P P A PP  L K     PP  A   L  L    
Sbjct: 437 APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQAL-PSP 495

Query: 191 PRLPPGRKP-------PGPPPGPPPPQVVQMYGRKVGFALDLPPRRRDEDMLYSP 238
           P   PG+ P       P  P   PPPQ   +    +   L +PP       L +P
Sbjct: 496 PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL---LQVPPSPPASPTLQAP 547



 Score = 31.6 bits (70), Expect = 2.4
 Identities = 23/78 (29%), Positives = 29/78 (37%), Gaps = 7/78 (8%)

Query: 140 PLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKP 199
           P P  P+A +  L+Q    P   PP     +    PP    +  P         PP + P
Sbjct: 384 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 443

Query: 200 PGPPPGP-------PPPQ 210
           P PP  P       PPPQ
Sbjct: 444 PSPPASPPMSPSATPPPQ 461


>gi|11386183 WAS protein family, member 2 [Homo sapiens]
          Length = 498

 Score = 94.7 bits (234), Expect = 2e-19
 Identities = 72/197 (36%), Positives = 85/197 (43%), Gaps = 28/197 (14%)

Query: 380 SDGTSTAS---SQQQAPPQSVPPSQIQAPP--MPGPPPLGPPPA----PPLRPPGPPTGL 430
           SD  S+ S   S+   PP   PP++   P     G    GP  +    P   PP PP G 
Sbjct: 252 SDSASSPSPSFSEDNLPP---PPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPLGS 308

Query: 431 PPGPPPG-APPFLRPPGMPGLRGPLPRLLPPGPPP---GRPPGPPPGPPPGLPP-----G 481
           PPGP PG APP   PP  P + G     +PP PPP   G P  PPP  PP  PP      
Sbjct: 309 PPGPKPGFAPPPAPPPPPPPMIG-----IPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAA 363

Query: 482 PPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLI 541
           PPP  PPP    P  P  P  +P    PP  PP  P PPG  PP      G  + PP L 
Sbjct: 364 PPPPPPPPAADYPTLPPPPLSQPTGGAPP--PPPPPPPPGPPPPPFTGADGQPAIPPPLS 421

Query: 542 QRPKADDTSAATIEKKA 558
              K   +  A  + ++
Sbjct: 422 DTTKPKSSLPAVSDARS 438



 Score = 92.4 bits (228), Expect = 1e-18
 Identities = 69/195 (35%), Positives = 80/195 (41%), Gaps = 20/195 (10%)

Query: 343 PEEGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQI 402
           P +       S    ED+     AE      ++  S   G   +S    + P   PP  +
Sbjct: 249 PPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPP--L 306

Query: 403 QAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPP------GAPPFLRPPGMPGLRGPLPR 456
            +PP P  P   PPPAPP  PP P  G+PP PPP      G PP   PP  P    P P 
Sbjct: 307 GSPPGP-KPGFAPPPAPP-PPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFP----PHPD 360

Query: 457 LLPPGPPPGRPPGPPPGPPPGLPPGPPPRG--PPPRLPPPAPPGIPPPRPGMMRPPLVPP 514
              P PPP  P    P  PP  PP   P G  PPP  PPP P   PPP  G    P +PP
Sbjct: 361 FAAPPPPPPPPAADYPTLPP--PPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPP 418

Query: 515 LGPAPPGLFPPAPLP 529
             P      P + LP
Sbjct: 419 --PLSDTTKPKSSLP 431



 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 50/131 (38%), Positives = 59/131 (45%), Gaps = 21/131 (16%)

Query: 392 APPQSVPPSQIQAPPM----PGPPPLG-------PPPAPPLRPPGPPTGLPPGPPPGAP- 439
           APP + PP     PPM    P PPP+G       PPP+PP  PP P    PP PPP    
Sbjct: 317 APPPAPPPPP---PPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAA 373

Query: 440 --PFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPP-GPPPGLPPGPPPRGPPPRLPPPAP 496
             P L PP +    G  P   PP PPPG  P PPP     G P  PPP     + P  + 
Sbjct: 374 DYPTLPPPPLSQPTGGAPPPPPPPPPPG--PPPPPFTGADGQPAIPPPLSDTTK-PKSSL 430

Query: 497 PGIPPPRPGMM 507
           P +   R  ++
Sbjct: 431 PAVSDARSDLL 441



 Score = 38.1 bits (87), Expect = 0.025
 Identities = 46/166 (27%), Positives = 73/166 (43%), Gaps = 33/166 (19%)

Query: 75  EKVLKDKRKKLRETFERILRLYEKENPDIYK-ELRKLEVEYEQ-KRAQLSQYFDAVKN-- 130
           EK+L+D +  ++E  +R  R  +K+NP+      RK++   E+ ++ ++ Q F   K   
Sbjct: 162 EKMLQDTKDIMKE--KRKHRKEKKDNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKL 219

Query: 131 ------------------AQHVEVESIPLP---DMPHAPSNILIQD-IPLPGAQ--PPSI 166
                              ++V+  S P P   D   +PS    +D +P P A+   P  
Sbjct: 220 GTSGYPPTLVYQNGSIGCVENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVD 279

Query: 167 LKKTSAYGPPTRAVSILPLLGHGVPRL--PPGRKPP-GPPPGPPPP 209
            ++ S    P R+  + P      P L  PPG KP   PPP PPPP
Sbjct: 280 NQRGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPP 325



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 28/92 (30%), Positives = 30/92 (32%), Gaps = 25/92 (27%)

Query: 471 PPGPPPGLPPGPPPRGPPPRLPPP------------------------APPGIPPPRPGM 506
           PP P       P P      LPPP                          P  PPP P +
Sbjct: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306

Query: 507 MRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPP 538
             PP  P  G APP   PP P P  G+   PP
Sbjct: 307 GSPP-GPKPGFAPPPAPPPPPPPMIGIPPPPP 337



 Score = 36.6 bits (83), Expect = 0.073
 Identities = 45/163 (27%), Positives = 52/163 (31%), Gaps = 26/163 (15%)

Query: 142 PDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPG 201
           P  P  PS     D   P   PP          PP      L     G P  PP    P 
Sbjct: 347 PPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPP-----LSQPTGGAPPPPP----PP 397

Query: 202 PPPGPPPPQVVQMYGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDVSSTSEDD----G 257
           PPPGPPPP      G+       +PP   D     S   A      D+ S          
Sbjct: 398 PPPGPPPPPFTGADGQPA-----IPPPLSDTTKPKSSLPAVSDARSDLLSAIRQGFQLRR 452

Query: 258 YPEDMDQDKHDDSTDDSDT--------DKSDGESDGDEFVHRD 292
             E  +Q+K D   +D  T        + SD E D  EF   D
Sbjct: 453 VEEQREQEKRDVVGNDVATILSRRIAVEYSDSEDDSSEFDEDD 495



 Score = 33.9 bits (76), Expect = 0.47
 Identities = 23/65 (35%), Positives = 26/65 (40%), Gaps = 17/65 (26%)

Query: 157 PLPGAQPPSILKKTSAYGPPTRAVSILPL---LGHGVPRLPPGRKPP---------GPPP 204
           P PG  PP      +   PP   + I P    +G G P  PP   PP          PPP
Sbjct: 312 PKPGFAPPP-----APPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPP 366

Query: 205 GPPPP 209
            PPPP
Sbjct: 367 PPPPP 371


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 94.7 bits (234), Expect = 2e-19
 Identities = 95/360 (26%), Positives = 134/360 (37%), Gaps = 32/360 (8%)

Query: 296 RDNNEEKKSGLSVRFADMPGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREVEEFSED 355
           + +N  +KS +SV      GK  K K   K  +P  A   R       EE +  +  + D
Sbjct: 418 QQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAAD 477

Query: 356 D----------DEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPS----Q 401
                      ++  S DS +   S+ +  + SH         ++ +P +S  PS    Q
Sbjct: 478 SVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQ 537

Query: 402 IQAPPM------PGPPPL----GPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLR 451
            +  P       P PPP      P PAPP R    PT  P    P  PP  R P      
Sbjct: 538 KETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYS 597

Query: 452 GPLPRLLPPGPPPGRPPGPPPGPPP-GLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPP 510
            P+ R   P PPP R    PP PP     P PPP+      PPP     P  +       
Sbjct: 598 PPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLS 657

Query: 511 LVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSAATIEKKATATIS-AKPQIT 569
                G +P      A  P P    +P     RP+A  TS++    +  A+ S  + Q  
Sbjct: 658 SKHRKGSSPSRSTREARSPQPNKRHSPS---PRPRAPQTSSSPPPVRRGASSSPQRRQSP 714

Query: 570 NPKAEITRFVPTALRVRRENKGATAAPQ---RKSEDDSAVPLAKAAPKSGPSVPVSVQTK 626
           +P     R V      ++  K A+ +PQ   R S   S     + A K  P+ P  VQ++
Sbjct: 715 SPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQ 774



 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 65/270 (24%), Positives = 99/270 (36%), Gaps = 32/270 (11%)

Query: 260 EDMDQDKHDDSTDDSDTDKSDGESDGDEFVHRDNGERDNNEEKKSGLSVRFADMPGKSRK 319
           +D D+DK D    +S  +K +          R    R  +  ++S   VR       SR 
Sbjct: 147 QDEDKDKRDKEEKESSREKRERSRSP-----RRRKSRSPSPRRRSS-PVRRERKRSHSRS 200

Query: 320 KKKNMKELTPLQAMMLRMAGQEIPEEGREVEEFSEDDDEDDSD--------------DSE 365
            +   K  +P  A   +    E+PE   +V+E S  +    SD              +  
Sbjct: 201 PRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPS 260

Query: 366 AEKQSQKQHKEE-----SHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPA-- 418
            EK S+K+ ++E     S S   S + ++ ++P  + P  + ++      P   P P   
Sbjct: 261 PEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRR 320

Query: 419 PPLRPPGPPTGLPPGPP---PGAPPFLRPPGMPGLRGPLPRLLPPGP--PPGRPPGPPPG 473
           P  R   PP  +PP P      +P   R      L G            PP +PP     
Sbjct: 321 PSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSS 380

Query: 474 PPPGLPPGPPPRGPPPRLPPPAPPGIPPPR 503
           PP       P   PP R   P+PP  PPP+
Sbjct: 381 PPRKTRRLSPSASPPRRRHRPSPPATPPPK 410


>gi|192807323 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform A [Homo sapiens]
          Length = 1679

 Score = 94.4 bits (233), Expect = 3e-19
 Identities = 113/392 (28%), Positives = 147/392 (37%), Gaps = 67/392 (17%)

Query: 191 PRLPPGRKP-PGPPPGPPPPQVVQMYGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDV 249
           P  P G  P PGP PGP P       G  +G +    P      M  SP     GH    
Sbjct: 4   PDPPLGGTPRPGPSPGPGPSP-----GAMLGPSPGPSPGSAHSMMGPSPGPPSAGHP--- 55

Query: 250 SSTSEDDGYPEDMDQDKHDDSTDDSDTDKSDGESDGDEFVHRDNGERDNNEEKKSGLSVR 309
             T    GYP+D     H                   E +H      D    +  G+ +R
Sbjct: 56  IPTQGPGGYPQDNMHQMHKPM----------------ESMHEKGMSDDPRYNQMKGMGMR 99

Query: 310 ---FADM-PGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREV-EEFSEDDDEDDSDDS 364
               A M P  S   + +    +PL       A   +P  G     + S        D +
Sbjct: 100 SGGHAGMGPPPSPMDQHSQGYPSPLGGS--EHASSPVPASGPSSGPQMSSGPGGAPLDGA 157

Query: 365 EAEKQSQKQ------HKEESHSDGTSTASSQQQAPPQSVPPSQIQAP----PMPGPP--- 411
           + +   Q+       ++ + H       + +  A  Q +P     A     PMPG     
Sbjct: 158 DPQALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQM 217

Query: 412 PLGPPPAPPLRPPGPPTGLPPGPPPG-APP-FLRPPGMPGLRGPLPRLLPPGPPPGRPPG 469
           P  PPP+     PGP  G  PGP PG APP + RP GM G     P + PPGP  G PPG
Sbjct: 218 PTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGG-----PNMPPPGPS-GVPPG 271

Query: 470 PPPGPPPGLPPGPPPRGP----------PPRLPPPAPPGIPPPRPGMMRP---PLVPPLG 516
             PG PPG PP P P GP          P +L PP P G P P P  + P   P++PP  
Sbjct: 272 -MPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMPPQT 330

Query: 517 PAPPGLFPPAPLPNPGVLSAPPNLIQRPKADD 548
            +P     PAP+       +    IQ+P+  D
Sbjct: 331 QSPGQPAQPAPMVPLHQKQSRITPIQKPRGLD 362



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 47/164 (28%), Positives = 51/164 (31%), Gaps = 45/164 (27%)

Query: 396 SVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPG-APPFLRP-PGMPGLRGP 453
           S P   +   P PGP P GP P+     PG   G  PGP PG A   + P PG P    P
Sbjct: 2   STPDPPLGGTPRPGPSP-GPGPS-----PGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHP 55

Query: 454 LPRLLPPGPPPGR------------------------------------PPGPPPGPPPG 477
           +P   P G P                                         GPPP P   
Sbjct: 56  IPTQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQ 115

Query: 478 LPPG-PPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPP 520
              G P P G       P P   P   P M   P   PL  A P
Sbjct: 116 HSQGYPSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADP 159



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 21/59 (35%), Positives = 24/59 (40%), Gaps = 7/59 (11%)

Query: 158 LPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPP------PPQ 210
           +PG QPP    K    GP   A +        +P  P GR  P PP  PP      PPQ
Sbjct: 272 MPG-QPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMPPQ 329



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 6/54 (11%)

Query: 157 PLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPP-PGPPPP 209
           P PG  PP+  +     GP     ++ P    GVP   PG+ P GPP P P  P
Sbjct: 240 PGPGPAPPNYSRPHGMGGP-----NMPPPGPSGVPPGMPGQPPGGPPKPWPEGP 288



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 16/88 (18%), Positives = 36/88 (40%), Gaps = 14/88 (15%)

Query: 278  KSDGESDGDEFVHRDNGERDNNEEKKSGLSVRFADMPGKSRKKKKNMKELTPLQAMMLRM 337
            + + +S+G+E    + GE + +E +   + V+     G+  K +  +K            
Sbjct: 1597 EKEDDSEGEESEEEEEGEEEGSESESRSVKVKI--KLGRKEKAQDRLK------------ 1642

Query: 338  AGQEIPEEGREVEEFSEDDDEDDSDDSE 365
             G+  P  G   +    DDD ++  + +
Sbjct: 1643 GGRRRPSRGSRAKPVVSDDDSEEEQEED 1670


>gi|192807320 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform F [Homo sapiens]
          Length = 1613

 Score = 94.4 bits (233), Expect = 3e-19
 Identities = 113/392 (28%), Positives = 147/392 (37%), Gaps = 67/392 (17%)

Query: 191 PRLPPGRKP-PGPPPGPPPPQVVQMYGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDV 249
           P  P G  P PGP PGP P       G  +G +    P      M  SP     GH    
Sbjct: 4   PDPPLGGTPRPGPSPGPGPSP-----GAMLGPSPGPSPGSAHSMMGPSPGPPSAGHP--- 55

Query: 250 SSTSEDDGYPEDMDQDKHDDSTDDSDTDKSDGESDGDEFVHRDNGERDNNEEKKSGLSVR 309
             T    GYP+D     H                   E +H      D    +  G+ +R
Sbjct: 56  IPTQGPGGYPQDNMHQMHKPM----------------ESMHEKGMSDDPRYNQMKGMGMR 99

Query: 310 ---FADM-PGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREV-EEFSEDDDEDDSDDS 364
               A M P  S   + +    +PL       A   +P  G     + S        D +
Sbjct: 100 SGGHAGMGPPPSPMDQHSQGYPSPLGGS--EHASSPVPASGPSSGPQMSSGPGGAPLDGA 157

Query: 365 EAEKQSQKQ------HKEESHSDGTSTASSQQQAPPQSVPPSQIQAP----PMPGPP--- 411
           + +   Q+       ++ + H       + +  A  Q +P     A     PMPG     
Sbjct: 158 DPQALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQM 217

Query: 412 PLGPPPAPPLRPPGPPTGLPPGPPPG-APP-FLRPPGMPGLRGPLPRLLPPGPPPGRPPG 469
           P  PPP+     PGP  G  PGP PG APP + RP GM G     P + PPGP  G PPG
Sbjct: 218 PTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGG-----PNMPPPGPS-GVPPG 271

Query: 470 PPPGPPPGLPPGPPPRGP----------PPRLPPPAPPGIPPPRPGMMRP---PLVPPLG 516
             PG PPG PP P P GP          P +L PP P G P P P  + P   P++PP  
Sbjct: 272 -MPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMPPQT 330

Query: 517 PAPPGLFPPAPLPNPGVLSAPPNLIQRPKADD 548
            +P     PAP+       +    IQ+P+  D
Sbjct: 331 QSPGQPAQPAPMVPLHQKQSRITPIQKPRGLD 362



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 47/164 (28%), Positives = 51/164 (31%), Gaps = 45/164 (27%)

Query: 396 SVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPG-APPFLRP-PGMPGLRGP 453
           S P   +   P PGP P GP P+     PG   G  PGP PG A   + P PG P    P
Sbjct: 2   STPDPPLGGTPRPGPSP-GPGPS-----PGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHP 55

Query: 454 LPRLLPPGPPPGR------------------------------------PPGPPPGPPPG 477
           +P   P G P                                         GPPP P   
Sbjct: 56  IPTQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQ 115

Query: 478 LPPG-PPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPP 520
              G P P G       P P   P   P M   P   PL  A P
Sbjct: 116 HSQGYPSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADP 159



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 21/59 (35%), Positives = 24/59 (40%), Gaps = 7/59 (11%)

Query: 158 LPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPP------PPQ 210
           +PG QPP    K    GP   A +        +P  P GR  P PP  PP      PPQ
Sbjct: 272 MPG-QPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMPPQ 329



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 6/54 (11%)

Query: 157 PLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPP-PGPPPP 209
           P PG  PP+  +     GP     ++ P    GVP   PG+ P GPP P P  P
Sbjct: 240 PGPGPAPPNYSRPHGMGGP-----NMPPPGPSGVPPGMPGQPPGGPPKPWPEGP 288



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 16/88 (18%), Positives = 36/88 (40%), Gaps = 14/88 (15%)

Query: 278  KSDGESDGDEFVHRDNGERDNNEEKKSGLSVRFADMPGKSRKKKKNMKELTPLQAMMLRM 337
            + + +S+G+E    + GE + +E +   + V+     G+  K +  +K            
Sbjct: 1531 EKEDDSEGEESEEEEEGEEEGSESESRSVKVKI--KLGRKEKAQDRLK------------ 1576

Query: 338  AGQEIPEEGREVEEFSEDDDEDDSDDSE 365
             G+  P  G   +    DDD ++  + +
Sbjct: 1577 GGRRRPSRGSRAKPVVSDDDSEEEQEED 1604


>gi|192807318 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform E [Homo sapiens]
          Length = 1614

 Score = 94.4 bits (233), Expect = 3e-19
 Identities = 113/392 (28%), Positives = 147/392 (37%), Gaps = 67/392 (17%)

Query: 191 PRLPPGRKP-PGPPPGPPPPQVVQMYGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDV 249
           P  P G  P PGP PGP P       G  +G +    P      M  SP     GH    
Sbjct: 4   PDPPLGGTPRPGPSPGPGPSP-----GAMLGPSPGPSPGSAHSMMGPSPGPPSAGHP--- 55

Query: 250 SSTSEDDGYPEDMDQDKHDDSTDDSDTDKSDGESDGDEFVHRDNGERDNNEEKKSGLSVR 309
             T    GYP+D     H                   E +H      D    +  G+ +R
Sbjct: 56  IPTQGPGGYPQDNMHQMHKPM----------------ESMHEKGMSDDPRYNQMKGMGMR 99

Query: 310 ---FADM-PGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREV-EEFSEDDDEDDSDDS 364
               A M P  S   + +    +PL       A   +P  G     + S        D +
Sbjct: 100 SGGHAGMGPPPSPMDQHSQGYPSPLGGS--EHASSPVPASGPSSGPQMSSGPGGAPLDGA 157

Query: 365 EAEKQSQKQ------HKEESHSDGTSTASSQQQAPPQSVPPSQIQAP----PMPGPP--- 411
           + +   Q+       ++ + H       + +  A  Q +P     A     PMPG     
Sbjct: 158 DPQALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQM 217

Query: 412 PLGPPPAPPLRPPGPPTGLPPGPPPG-APP-FLRPPGMPGLRGPLPRLLPPGPPPGRPPG 469
           P  PPP+     PGP  G  PGP PG APP + RP GM G     P + PPGP  G PPG
Sbjct: 218 PTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGG-----PNMPPPGPS-GVPPG 271

Query: 470 PPPGPPPGLPPGPPPRGP----------PPRLPPPAPPGIPPPRPGMMRP---PLVPPLG 516
             PG PPG PP P P GP          P +L PP P G P P P  + P   P++PP  
Sbjct: 272 -MPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMPPQT 330

Query: 517 PAPPGLFPPAPLPNPGVLSAPPNLIQRPKADD 548
            +P     PAP+       +    IQ+P+  D
Sbjct: 331 QSPGQPAQPAPMVPLHQKQSRITPIQKPRGLD 362



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 47/164 (28%), Positives = 51/164 (31%), Gaps = 45/164 (27%)

Query: 396 SVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPG-APPFLRP-PGMPGLRGP 453
           S P   +   P PGP P GP P+     PG   G  PGP PG A   + P PG P    P
Sbjct: 2   STPDPPLGGTPRPGPSP-GPGPS-----PGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHP 55

Query: 454 LPRLLPPGPPPGR------------------------------------PPGPPPGPPPG 477
           +P   P G P                                         GPPP P   
Sbjct: 56  IPTQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQ 115

Query: 478 LPPG-PPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPP 520
              G P P G       P P   P   P M   P   PL  A P
Sbjct: 116 HSQGYPSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADP 159



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 21/59 (35%), Positives = 24/59 (40%), Gaps = 7/59 (11%)

Query: 158 LPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPP------PPQ 210
           +PG QPP    K    GP   A +        +P  P GR  P PP  PP      PPQ
Sbjct: 272 MPG-QPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMPPQ 329



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 6/54 (11%)

Query: 157 PLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPP-PGPPPP 209
           P PG  PP+  +     GP     ++ P    GVP   PG+ P GPP P P  P
Sbjct: 240 PGPGPAPPNYSRPHGMGGP-----NMPPPGPSGVPPGMPGQPPGGPPKPWPEGP 288



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 16/88 (18%), Positives = 36/88 (40%), Gaps = 14/88 (15%)

Query: 278  KSDGESDGDEFVHRDNGERDNNEEKKSGLSVRFADMPGKSRKKKKNMKELTPLQAMMLRM 337
            + + +S+G+E    + GE + +E +   + V+     G+  K +  +K            
Sbjct: 1532 EKEDDSEGEESEEEEEGEEEGSESESRSVKVKI--KLGRKEKAQDRLK------------ 1577

Query: 338  AGQEIPEEGREVEEFSEDDDEDDSDDSE 365
             G+  P  G   +    DDD ++  + +
Sbjct: 1578 GGRRRPSRGSRAKPVVSDDDSEEEQEED 1605


>gi|192807316 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform D [Homo sapiens]
          Length = 1616

 Score = 94.4 bits (233), Expect = 3e-19
 Identities = 113/392 (28%), Positives = 147/392 (37%), Gaps = 67/392 (17%)

Query: 191 PRLPPGRKP-PGPPPGPPPPQVVQMYGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDV 249
           P  P G  P PGP PGP P       G  +G +    P      M  SP     GH    
Sbjct: 4   PDPPLGGTPRPGPSPGPGPSP-----GAMLGPSPGPSPGSAHSMMGPSPGPPSAGHP--- 55

Query: 250 SSTSEDDGYPEDMDQDKHDDSTDDSDTDKSDGESDGDEFVHRDNGERDNNEEKKSGLSVR 309
             T    GYP+D     H                   E +H      D    +  G+ +R
Sbjct: 56  IPTQGPGGYPQDNMHQMHKPM----------------ESMHEKGMSDDPRYNQMKGMGMR 99

Query: 310 ---FADM-PGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREV-EEFSEDDDEDDSDDS 364
               A M P  S   + +    +PL       A   +P  G     + S        D +
Sbjct: 100 SGGHAGMGPPPSPMDQHSQGYPSPLGGS--EHASSPVPASGPSSGPQMSSGPGGAPLDGA 157

Query: 365 EAEKQSQKQ------HKEESHSDGTSTASSQQQAPPQSVPPSQIQAP----PMPGPP--- 411
           + +   Q+       ++ + H       + +  A  Q +P     A     PMPG     
Sbjct: 158 DPQALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQM 217

Query: 412 PLGPPPAPPLRPPGPPTGLPPGPPPG-APP-FLRPPGMPGLRGPLPRLLPPGPPPGRPPG 469
           P  PPP+     PGP  G  PGP PG APP + RP GM G     P + PPGP  G PPG
Sbjct: 218 PTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGG-----PNMPPPGPS-GVPPG 271

Query: 470 PPPGPPPGLPPGPPPRGP----------PPRLPPPAPPGIPPPRPGMMRP---PLVPPLG 516
             PG PPG PP P P GP          P +L PP P G P P P  + P   P++PP  
Sbjct: 272 -MPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMPPQT 330

Query: 517 PAPPGLFPPAPLPNPGVLSAPPNLIQRPKADD 548
            +P     PAP+       +    IQ+P+  D
Sbjct: 331 QSPGQPAQPAPMVPLHQKQSRITPIQKPRGLD 362



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 47/164 (28%), Positives = 51/164 (31%), Gaps = 45/164 (27%)

Query: 396 SVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPG-APPFLRP-PGMPGLRGP 453
           S P   +   P PGP P GP P+     PG   G  PGP PG A   + P PG P    P
Sbjct: 2   STPDPPLGGTPRPGPSP-GPGPS-----PGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHP 55

Query: 454 LPRLLPPGPPPGR------------------------------------PPGPPPGPPPG 477
           +P   P G P                                         GPPP P   
Sbjct: 56  IPTQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQ 115

Query: 478 LPPG-PPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPP 520
              G P P G       P P   P   P M   P   PL  A P
Sbjct: 116 HSQGYPSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADP 159



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 21/59 (35%), Positives = 24/59 (40%), Gaps = 7/59 (11%)

Query: 158 LPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPP------PPQ 210
           +PG QPP    K    GP   A +        +P  P GR  P PP  PP      PPQ
Sbjct: 272 MPG-QPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMPPQ 329



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 6/54 (11%)

Query: 157 PLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPP-PGPPPP 209
           P PG  PP+  +     GP     ++ P    GVP   PG+ P GPP P P  P
Sbjct: 240 PGPGPAPPNYSRPHGMGGP-----NMPPPGPSGVPPGMPGQPPGGPPKPWPEGP 288



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 16/88 (18%), Positives = 36/88 (40%), Gaps = 14/88 (15%)

Query: 278  KSDGESDGDEFVHRDNGERDNNEEKKSGLSVRFADMPGKSRKKKKNMKELTPLQAMMLRM 337
            + + +S+G+E    + GE + +E +   + V+     G+  K +  +K            
Sbjct: 1534 EKEDDSEGEESEEEEEGEEEGSESESRSVKVKI--KLGRKEKAQDRLK------------ 1579

Query: 338  AGQEIPEEGREVEEFSEDDDEDDSDDSE 365
             G+  P  G   +    DDD ++  + +
Sbjct: 1580 GGRRRPSRGSRAKPVVSDDDSEEEQEED 1607


>gi|192807314 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform C [Homo sapiens]
          Length = 1617

 Score = 94.4 bits (233), Expect = 3e-19
 Identities = 113/392 (28%), Positives = 147/392 (37%), Gaps = 67/392 (17%)

Query: 191 PRLPPGRKP-PGPPPGPPPPQVVQMYGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDV 249
           P  P G  P PGP PGP P       G  +G +    P      M  SP     GH    
Sbjct: 4   PDPPLGGTPRPGPSPGPGPSP-----GAMLGPSPGPSPGSAHSMMGPSPGPPSAGHP--- 55

Query: 250 SSTSEDDGYPEDMDQDKHDDSTDDSDTDKSDGESDGDEFVHRDNGERDNNEEKKSGLSVR 309
             T    GYP+D     H                   E +H      D    +  G+ +R
Sbjct: 56  IPTQGPGGYPQDNMHQMHKPM----------------ESMHEKGMSDDPRYNQMKGMGMR 99

Query: 310 ---FADM-PGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREV-EEFSEDDDEDDSDDS 364
               A M P  S   + +    +PL       A   +P  G     + S        D +
Sbjct: 100 SGGHAGMGPPPSPMDQHSQGYPSPLGGS--EHASSPVPASGPSSGPQMSSGPGGAPLDGA 157

Query: 365 EAEKQSQKQ------HKEESHSDGTSTASSQQQAPPQSVPPSQIQAP----PMPGPP--- 411
           + +   Q+       ++ + H       + +  A  Q +P     A     PMPG     
Sbjct: 158 DPQALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQM 217

Query: 412 PLGPPPAPPLRPPGPPTGLPPGPPPG-APP-FLRPPGMPGLRGPLPRLLPPGPPPGRPPG 469
           P  PPP+     PGP  G  PGP PG APP + RP GM G     P + PPGP  G PPG
Sbjct: 218 PTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGG-----PNMPPPGPS-GVPPG 271

Query: 470 PPPGPPPGLPPGPPPRGP----------PPRLPPPAPPGIPPPRPGMMRP---PLVPPLG 516
             PG PPG PP P P GP          P +L PP P G P P P  + P   P++PP  
Sbjct: 272 -MPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMPPQT 330

Query: 517 PAPPGLFPPAPLPNPGVLSAPPNLIQRPKADD 548
            +P     PAP+       +    IQ+P+  D
Sbjct: 331 QSPGQPAQPAPMVPLHQKQSRITPIQKPRGLD 362



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 47/164 (28%), Positives = 51/164 (31%), Gaps = 45/164 (27%)

Query: 396 SVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPG-APPFLRP-PGMPGLRGP 453
           S P   +   P PGP P GP P+     PG   G  PGP PG A   + P PG P    P
Sbjct: 2   STPDPPLGGTPRPGPSP-GPGPS-----PGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHP 55

Query: 454 LPRLLPPGPPPGR------------------------------------PPGPPPGPPPG 477
           +P   P G P                                         GPPP P   
Sbjct: 56  IPTQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQ 115

Query: 478 LPPG-PPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPP 520
              G P P G       P P   P   P M   P   PL  A P
Sbjct: 116 HSQGYPSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADP 159



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 21/59 (35%), Positives = 24/59 (40%), Gaps = 7/59 (11%)

Query: 158 LPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPP------PPQ 210
           +PG QPP    K    GP   A +        +P  P GR  P PP  PP      PPQ
Sbjct: 272 MPG-QPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMPPQ 329



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 6/54 (11%)

Query: 157 PLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPP-PGPPPP 209
           P PG  PP+  +     GP     ++ P    GVP   PG+ P GPP P P  P
Sbjct: 240 PGPGPAPPNYSRPHGMGGP-----NMPPPGPSGVPPGMPGQPPGGPPKPWPEGP 288



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 16/88 (18%), Positives = 36/88 (40%), Gaps = 14/88 (15%)

Query: 278  KSDGESDGDEFVHRDNGERDNNEEKKSGLSVRFADMPGKSRKKKKNMKELTPLQAMMLRM 337
            + + +S+G+E    + GE + +E +   + V+     G+  K +  +K            
Sbjct: 1535 EKEDDSEGEESEEEEEGEEEGSESESRSVKVKI--KLGRKEKAQDRLK------------ 1580

Query: 338  AGQEIPEEGREVEEFSEDDDEDDSDDSE 365
             G+  P  G   +    DDD ++  + +
Sbjct: 1581 GGRRRPSRGSRAKPVVSDDDSEEEQEED 1608


>gi|192807312 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform B [Homo sapiens]
          Length = 1647

 Score = 94.4 bits (233), Expect = 3e-19
 Identities = 113/392 (28%), Positives = 147/392 (37%), Gaps = 67/392 (17%)

Query: 191 PRLPPGRKP-PGPPPGPPPPQVVQMYGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDV 249
           P  P G  P PGP PGP P       G  +G +    P      M  SP     GH    
Sbjct: 4   PDPPLGGTPRPGPSPGPGPSP-----GAMLGPSPGPSPGSAHSMMGPSPGPPSAGHP--- 55

Query: 250 SSTSEDDGYPEDMDQDKHDDSTDDSDTDKSDGESDGDEFVHRDNGERDNNEEKKSGLSVR 309
             T    GYP+D     H                   E +H      D    +  G+ +R
Sbjct: 56  IPTQGPGGYPQDNMHQMHKPM----------------ESMHEKGMSDDPRYNQMKGMGMR 99

Query: 310 ---FADM-PGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREV-EEFSEDDDEDDSDDS 364
               A M P  S   + +    +PL       A   +P  G     + S        D +
Sbjct: 100 SGGHAGMGPPPSPMDQHSQGYPSPLGGS--EHASSPVPASGPSSGPQMSSGPGGAPLDGA 157

Query: 365 EAEKQSQKQ------HKEESHSDGTSTASSQQQAPPQSVPPSQIQAP----PMPGPP--- 411
           + +   Q+       ++ + H       + +  A  Q +P     A     PMPG     
Sbjct: 158 DPQALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQM 217

Query: 412 PLGPPPAPPLRPPGPPTGLPPGPPPG-APP-FLRPPGMPGLRGPLPRLLPPGPPPGRPPG 469
           P  PPP+     PGP  G  PGP PG APP + RP GM G     P + PPGP  G PPG
Sbjct: 218 PTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGG-----PNMPPPGPS-GVPPG 271

Query: 470 PPPGPPPGLPPGPPPRGP----------PPRLPPPAPPGIPPPRPGMMRP---PLVPPLG 516
             PG PPG PP P P GP          P +L PP P G P P P  + P   P++PP  
Sbjct: 272 -MPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMPPQT 330

Query: 517 PAPPGLFPPAPLPNPGVLSAPPNLIQRPKADD 548
            +P     PAP+       +    IQ+P+  D
Sbjct: 331 QSPGQPAQPAPMVPLHQKQSRITPIQKPRGLD 362



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 47/164 (28%), Positives = 51/164 (31%), Gaps = 45/164 (27%)

Query: 396 SVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPG-APPFLRP-PGMPGLRGP 453
           S P   +   P PGP P GP P+     PG   G  PGP PG A   + P PG P    P
Sbjct: 2   STPDPPLGGTPRPGPSP-GPGPS-----PGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHP 55

Query: 454 LPRLLPPGPPPGR------------------------------------PPGPPPGPPPG 477
           +P   P G P                                         GPPP P   
Sbjct: 56  IPTQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQ 115

Query: 478 LPPG-PPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPP 520
              G P P G       P P   P   P M   P   PL  A P
Sbjct: 116 HSQGYPSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADP 159



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 21/59 (35%), Positives = 24/59 (40%), Gaps = 7/59 (11%)

Query: 158 LPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPP------PPQ 210
           +PG QPP    K    GP   A +        +P  P GR  P PP  PP      PPQ
Sbjct: 272 MPG-QPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMPPQ 329



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 6/54 (11%)

Query: 157 PLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPP-PGPPPP 209
           P PG  PP+  +     GP     ++ P    GVP   PG+ P GPP P P  P
Sbjct: 240 PGPGPAPPNYSRPHGMGGP-----NMPPPGPSGVPPGMPGQPPGGPPKPWPEGP 288



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 16/88 (18%), Positives = 36/88 (40%), Gaps = 14/88 (15%)

Query: 278  KSDGESDGDEFVHRDNGERDNNEEKKSGLSVRFADMPGKSRKKKKNMKELTPLQAMMLRM 337
            + + +S+G+E    + GE + +E +   + V+     G+  K +  +K            
Sbjct: 1565 EKEDDSEGEESEEEEEGEEEGSESESRSVKVKI--KLGRKEKAQDRLK------------ 1610

Query: 338  AGQEIPEEGREVEEFSEDDDEDDSDDSE 365
             G+  P  G   +    DDD ++  + +
Sbjct: 1611 GGRRRPSRGSRAKPVVSDDDSEEEQEED 1638


>gi|21071056 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform B [Homo sapiens]
          Length = 1647

 Score = 94.4 bits (233), Expect = 3e-19
 Identities = 113/392 (28%), Positives = 147/392 (37%), Gaps = 67/392 (17%)

Query: 191 PRLPPGRKP-PGPPPGPPPPQVVQMYGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDV 249
           P  P G  P PGP PGP P       G  +G +    P      M  SP     GH    
Sbjct: 4   PDPPLGGTPRPGPSPGPGPSP-----GAMLGPSPGPSPGSAHSMMGPSPGPPSAGHP--- 55

Query: 250 SSTSEDDGYPEDMDQDKHDDSTDDSDTDKSDGESDGDEFVHRDNGERDNNEEKKSGLSVR 309
             T    GYP+D     H                   E +H      D    +  G+ +R
Sbjct: 56  IPTQGPGGYPQDNMHQMHKPM----------------ESMHEKGMSDDPRYNQMKGMGMR 99

Query: 310 ---FADM-PGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREV-EEFSEDDDEDDSDDS 364
               A M P  S   + +    +PL       A   +P  G     + S        D +
Sbjct: 100 SGGHAGMGPPPSPMDQHSQGYPSPLGGS--EHASSPVPASGPSSGPQMSSGPGGAPLDGA 157

Query: 365 EAEKQSQKQ------HKEESHSDGTSTASSQQQAPPQSVPPSQIQAP----PMPGPP--- 411
           + +   Q+       ++ + H       + +  A  Q +P     A     PMPG     
Sbjct: 158 DPQALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQM 217

Query: 412 PLGPPPAPPLRPPGPPTGLPPGPPPG-APP-FLRPPGMPGLRGPLPRLLPPGPPPGRPPG 469
           P  PPP+     PGP  G  PGP PG APP + RP GM G     P + PPGP  G PPG
Sbjct: 218 PTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGG-----PNMPPPGPS-GVPPG 271

Query: 470 PPPGPPPGLPPGPPPRGP----------PPRLPPPAPPGIPPPRPGMMRP---PLVPPLG 516
             PG PPG PP P P GP          P +L PP P G P P P  + P   P++PP  
Sbjct: 272 -MPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMPPQT 330

Query: 517 PAPPGLFPPAPLPNPGVLSAPPNLIQRPKADD 548
            +P     PAP+       +    IQ+P+  D
Sbjct: 331 QSPGQPAQPAPMVPLHQKQSRITPIQKPRGLD 362



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 47/164 (28%), Positives = 51/164 (31%), Gaps = 45/164 (27%)

Query: 396 SVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPG-APPFLRP-PGMPGLRGP 453
           S P   +   P PGP P GP P+     PG   G  PGP PG A   + P PG P    P
Sbjct: 2   STPDPPLGGTPRPGPSP-GPGPS-----PGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHP 55

Query: 454 LPRLLPPGPPPGR------------------------------------PPGPPPGPPPG 477
           +P   P G P                                         GPPP P   
Sbjct: 56  IPTQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQ 115

Query: 478 LPPG-PPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPP 520
              G P P G       P P   P   P M   P   PL  A P
Sbjct: 116 HSQGYPSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADP 159



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 21/59 (35%), Positives = 24/59 (40%), Gaps = 7/59 (11%)

Query: 158 LPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPP------PPQ 210
           +PG QPP    K    GP   A +        +P  P GR  P PP  PP      PPQ
Sbjct: 272 MPG-QPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVMPPQ 329



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 6/54 (11%)

Query: 157 PLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPP-PGPPPP 209
           P PG  PP+  +     GP     ++ P    GVP   PG+ P GPP P P  P
Sbjct: 240 PGPGPAPPNYSRPHGMGGP-----NMPPPGPSGVPPGMPGQPPGGPPKPWPEGP 288



 Score = 29.6 bits (65), Expect = 8.9
 Identities = 16/88 (18%), Positives = 36/88 (40%), Gaps = 14/88 (15%)

Query: 278  KSDGESDGDEFVHRDNGERDNNEEKKSGLSVRFADMPGKSRKKKKNMKELTPLQAMMLRM 337
            + + +S+G+E    + GE + +E +   + V+     G+  K +  +K            
Sbjct: 1565 EKEDDSEGEESEEEEEGEEEGSESESRSVKVKI--KLGRKEKAQDRLK------------ 1610

Query: 338  AGQEIPEEGREVEEFSEDDDEDDSDDSE 365
             G+  P  G   +    DDD ++  + +
Sbjct: 1611 GGRRRPSRGSRAKPVVSDDDSEEEQEED 1638


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,779,662
Number of Sequences: 37866
Number of extensions: 4206575
Number of successful extensions: 160723
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1952
Number of HSP's successfully gapped in prelim test: 2385
Number of HSP's that attempted gapping in prelim test: 25142
Number of HSP's gapped (non-prelim): 46273
length of query: 641
length of database: 18,247,518
effective HSP length: 109
effective length of query: 532
effective length of database: 14,120,124
effective search space: 7511905968
effective search space used: 7511905968
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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