Guide to the Human Genome
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Search of human proteins with 7705999

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7705999 transmembrane protein 9 [Homo sapiens]
         (183 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7705999 transmembrane protein 9 [Homo sapiens]                     373   e-104
gi|11034855 TMEM9 domain family, member B [Homo sapiens]              213   1e-55
gi|114326453 a disintegrin and metalloproteinase domain 7 [Homo ...    31   0.68 
gi|58761548 tau tubulin kinase 1 [Homo sapiens]                        28   4.4  
gi|115583667 sodium channel, voltage-gated, type XI, alpha [Homo...    28   4.4  
gi|116534898 desmoglein 2 preproprotein [Homo sapiens]                 28   5.7  
gi|74027265 serine peptidase inhibitor, Kunitz type 1 isoform 2 ...    28   5.7  
gi|4504329 serine peptidase inhibitor, Kunitz type 1 isoform 2 p...    28   5.7  
gi|32313599 serine peptidase inhibitor, Kunitz type 1 isoform 1 ...    28   5.7  
gi|4757710 amiloride-sensitive cation channel 3 isoform a [Homo ...    27   7.5  
gi|9998946 amiloride-sensitive cation channel 3 isoform b [Homo ...    27   7.5  
gi|9998948 amiloride-sensitive cation channel 3 isoform c [Homo ...    27   7.5  
gi|222352177 nuclear factor of kappa light polypeptide gene enha...    27   9.8  
gi|125628636 keratin 80 isoform a [Homo sapiens]                       27   9.8  
gi|125628632 keratin 80 isoform b [Homo sapiens]                       27   9.8  
gi|222352179 nuclear factor of kappa light polypeptide gene enha...    27   9.8  
gi|222352175 nuclear factor of kappa light polypeptide gene enha...    27   9.8  
gi|222352173 nuclear factor of kappa light polypeptide gene enha...    27   9.8  
gi|194097352 actinin, alpha 1 isoform c [Homo sapiens]                 27   9.8  
gi|194097350 actinin, alpha 1 isoform a [Homo sapiens]                 27   9.8  
gi|4501891 actinin, alpha 1 isoform b [Homo sapiens]                   27   9.8  

>gi|7705999 transmembrane protein 9 [Homo sapiens]
          Length = 183

 Score =  373 bits (958), Expect = e-104
 Identities = 183/183 (100%), Positives = 183/183 (100%)

Query: 1   MKLLSLVAVVGCLLVPPAEANKSSEDIRCKCICPPYRNISGHIYNQNVSQKDCNCLHVVE 60
           MKLLSLVAVVGCLLVPPAEANKSSEDIRCKCICPPYRNISGHIYNQNVSQKDCNCLHVVE
Sbjct: 1   MKLLSLVAVVGCLLVPPAEANKSSEDIRCKCICPPYRNISGHIYNQNVSQKDCNCLHVVE 60

Query: 61  PMPVPGHDVEAYCLLCECRYEERSTTTIKVIIVIYLSVVGALLLYMAFLMLVDPLIRKPD 120
           PMPVPGHDVEAYCLLCECRYEERSTTTIKVIIVIYLSVVGALLLYMAFLMLVDPLIRKPD
Sbjct: 61  PMPVPGHDVEAYCLLCECRYEERSTTTIKVIIVIYLSVVGALLLYMAFLMLVDPLIRKPD 120

Query: 121 AYTEQLHNEEENEDARSMAAAAASLGGPRANTVLERVEGAQQRWKLQVQEQRKTVFDRHK 180
           AYTEQLHNEEENEDARSMAAAAASLGGPRANTVLERVEGAQQRWKLQVQEQRKTVFDRHK
Sbjct: 121 AYTEQLHNEEENEDARSMAAAAASLGGPRANTVLERVEGAQQRWKLQVQEQRKTVFDRHK 180

Query: 181 MLS 183
           MLS
Sbjct: 181 MLS 183


>gi|11034855 TMEM9 domain family, member B [Homo sapiens]
          Length = 198

 Score =  213 bits (541), Expect = 1e-55
 Identities = 106/182 (58%), Positives = 138/182 (75%), Gaps = 2/182 (1%)

Query: 4   LSLVAVVGCLLVPPAEANKSSEDIRCKCICPPYRNISGHIYNQNVSQKDCNCLHVVEPMP 63
           LS +A+   LL   ++A K+ ED+RCKCICPPY+  SGHIYN+N+SQKDC+CLHVVEPMP
Sbjct: 17  LSCLALSVLLLAQLSDAAKNFEDVRCKCICPPYKENSGHIYNKNISQKDCDCLHVVEPMP 76

Query: 64  VPGHDVEAYCLLCECRYEERSTTTIKVIIVIYLSVVGALLLYMAFLMLVDPLI-RKPDAY 122
           V G DVEAYCL CEC+YEERS+ TIKV I+IYLS++G LLLYM +L LV+P++ R+   +
Sbjct: 77  VRGPDVEAYCLRCECKYEERSSVTIKVTIIIYLSILGLLLLYMVYLTLVEPILKRRLFGH 136

Query: 123 TEQLHNEEENEDARSMAAAAASLGGPRAN-TVLERVEGAQQRWKLQVQEQRKTVFDRHKM 181
            + + ++++  D +  A A   L   R+   VL +VE AQQRWKLQVQEQRK+VFDRH +
Sbjct: 137 AQLIQSDDDIGDHQPFANAHDVLARSRSRANVLNKVEYAQQRWKLQVQEQRKSVFDRHVV 196

Query: 182 LS 183
           LS
Sbjct: 197 LS 198


>gi|114326453 a disintegrin and metalloproteinase domain 7 [Homo
           sapiens]
          Length = 754

 Score = 30.8 bits (68), Expect = 0.68
 Identities = 17/75 (22%), Positives = 32/75 (42%), Gaps = 6/75 (8%)

Query: 40  SGHIYNQNVSQKDCNCLHVVEPMPVPGHDVEAYC------LLCECRYEERSTTTIKVIIV 93
           +G   N        NC       PV GH ++ +C      + CE      + T + V++V
Sbjct: 618 NGECLNMEKVYISTNCPSQCNENPVDGHGLQCHCEEGQAPVACEETLHVTNITILVVVLV 677

Query: 94  IYLSVVGALLLYMAF 108
           + +  +G L+L + +
Sbjct: 678 LVIVGIGVLILLVRY 692


>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
          Length = 1321

 Score = 28.1 bits (61), Expect = 4.4
 Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 3/43 (6%)

Query: 124 EQLHNEEENEDARSMAAAAASLG---GPRANTVLERVEGAQQR 163
           E+   EEE E+    AAAA +LG   GPR+ +  E  E +  R
Sbjct: 757 EEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSEGSERSTDR 799


>gi|115583667 sodium channel, voltage-gated, type XI, alpha [Homo
           sapiens]
          Length = 1791

 Score = 28.1 bits (61), Expect = 4.4
 Identities = 11/36 (30%), Positives = 24/36 (66%)

Query: 77  ECRYEERSTTTIKVIIVIYLSVVGALLLYMAFLMLV 112
           EC  E  +++++ VI+ I ++V+G L++   F+ L+
Sbjct: 775 ECMQEANASSSLCVIVFILITVIGKLVVLNLFIALL 810


>gi|116534898 desmoglein 2 preproprotein [Homo sapiens]
          Length = 1118

 Score = 27.7 bits (60), Expect = 5.7
 Identities = 19/106 (17%), Positives = 48/106 (45%), Gaps = 7/106 (6%)

Query: 77  ECRYEERSTTTIKVIIVIY----LSVVGALLLYMAFLMLVDPLIRKPDAYTEQLHNEEEN 132
           E RY +  T T+K++ +       ++ G +L+ +  +    P + +P    + + ++ E 
Sbjct: 456 ESRYVQNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCPTLIEP---VQTICHDAEY 512

Query: 133 EDARSMAAAAASLGGPRANTVLERVEGAQQRWKLQVQEQRKTVFDR 178
            +  +         GP + +V+++  G  ++WK+  QE    +  +
Sbjct: 513 VNVTAEDLDGHPNSGPFSFSVIDKPPGMAEKWKIARQESTSVLLQQ 558


>gi|74027265 serine peptidase inhibitor, Kunitz type 1 isoform 2
           precursor [Homo sapiens]
          Length = 513

 Score = 27.7 bits (60), Expect = 5.7
 Identities = 14/32 (43%), Positives = 18/32 (56%), Gaps = 1/32 (3%)

Query: 51  KDCNCLHVVEPMPVPGHDVEAYCLLCECRYEE 82
           ++CN L +VE  P  G D  A C L  C YE+
Sbjct: 95  QNCN-LALVELQPDRGEDAIAACFLINCLYEQ 125


>gi|4504329 serine peptidase inhibitor, Kunitz type 1 isoform 2
           precursor [Homo sapiens]
          Length = 513

 Score = 27.7 bits (60), Expect = 5.7
 Identities = 14/32 (43%), Positives = 18/32 (56%), Gaps = 1/32 (3%)

Query: 51  KDCNCLHVVEPMPVPGHDVEAYCLLCECRYEE 82
           ++CN L +VE  P  G D  A C L  C YE+
Sbjct: 95  QNCN-LALVELQPDRGEDAIAACFLINCLYEQ 125


>gi|32313599 serine peptidase inhibitor, Kunitz type 1 isoform 1
           precursor [Homo sapiens]
          Length = 529

 Score = 27.7 bits (60), Expect = 5.7
 Identities = 14/32 (43%), Positives = 18/32 (56%), Gaps = 1/32 (3%)

Query: 51  KDCNCLHVVEPMPVPGHDVEAYCLLCECRYEE 82
           ++CN L +VE  P  G D  A C L  C YE+
Sbjct: 95  QNCN-LALVELQPDRGEDAIAACFLINCLYEQ 125


>gi|4757710 amiloride-sensitive cation channel 3 isoform a [Homo
           sapiens]
          Length = 531

 Score = 27.3 bits (59), Expect = 7.5
 Identities = 18/78 (23%), Positives = 32/78 (41%)

Query: 6   LVAVVGCLLVPPAEANKSSEDIRCKCICPPYRNISGHIYNQNVSQKDCNCLHVVEPMPVP 65
           ++  +G  + P  +   S +  +   + PP+ + S    N N   +  + L    P P P
Sbjct: 249 IIDQLGLGVSPGYQTFVSCQQQQLSFLPPPWGDCSSASLNPNYEPEPSDPLGSPSPSPSP 308

Query: 66  GHDVEAYCLLCECRYEER 83
            + +    L CE RY  R
Sbjct: 309 PYTLMGCRLACETRYVAR 326


>gi|9998946 amiloride-sensitive cation channel 3 isoform b [Homo
           sapiens]
          Length = 549

 Score = 27.3 bits (59), Expect = 7.5
 Identities = 18/78 (23%), Positives = 32/78 (41%)

Query: 6   LVAVVGCLLVPPAEANKSSEDIRCKCICPPYRNISGHIYNQNVSQKDCNCLHVVEPMPVP 65
           ++  +G  + P  +   S +  +   + PP+ + S    N N   +  + L    P P P
Sbjct: 249 IIDQLGLGVSPGYQTFVSCQQQQLSFLPPPWGDCSSASLNPNYEPEPSDPLGSPSPSPSP 308

Query: 66  GHDVEAYCLLCECRYEER 83
            + +    L CE RY  R
Sbjct: 309 PYTLMGCRLACETRYVAR 326


>gi|9998948 amiloride-sensitive cation channel 3 isoform c [Homo
           sapiens]
          Length = 543

 Score = 27.3 bits (59), Expect = 7.5
 Identities = 18/78 (23%), Positives = 32/78 (41%)

Query: 6   LVAVVGCLLVPPAEANKSSEDIRCKCICPPYRNISGHIYNQNVSQKDCNCLHVVEPMPVP 65
           ++  +G  + P  +   S +  +   + PP+ + S    N N   +  + L    P P P
Sbjct: 249 IIDQLGLGVSPGYQTFVSCQQQQLSFLPPPWGDCSSASLNPNYEPEPSDPLGSPSPSPSP 308

Query: 66  GHDVEAYCLLCECRYEER 83
            + +    L CE RY  R
Sbjct: 309 PYTLMGCRLACETRYVAR 326


>gi|222352177 nuclear factor of kappa light polypeptide gene
           enhancer in B-cells inhibitor-like 1 isoform 3 [Homo
           sapiens]
          Length = 358

 Score = 26.9 bits (58), Expect = 9.8
 Identities = 16/52 (30%), Positives = 25/52 (48%), Gaps = 7/52 (13%)

Query: 121 AYTEQLHNEEENEDARSMAAAAASLGGPRANTVLERVEGAQQRWKLQVQEQR 172
           A++++L  E   +  +    A  S   PRA       EG+ Q W+ Q +EQR
Sbjct: 177 AWSDRLAREHAQKCQQQQREAEGSRRPPRA-------EGSSQSWRQQEEEQR 221


>gi|125628636 keratin 80 isoform a [Homo sapiens]
          Length = 452

 Score = 26.9 bits (58), Expect = 9.8
 Identities = 21/67 (31%), Positives = 36/67 (53%), Gaps = 3/67 (4%)

Query: 111 LVDPLIRKPDAYTEQLHNEEENEDARSMAAAAASLGGPRANTVLERVEGAQQRWKLQVQE 170
           L+ PL  K D   +QL N+E+ E+ +++    ASL G +   + +R +  + RW   +Q 
Sbjct: 64  LLVPLDVKLDPAVQQLKNQEK-EEMKALNDKFASLIG-KVQALEQRNQLLETRWSF-LQG 120

Query: 171 QRKTVFD 177
           Q   +FD
Sbjct: 121 QDSAIFD 127


>gi|125628632 keratin 80 isoform b [Homo sapiens]
          Length = 422

 Score = 26.9 bits (58), Expect = 9.8
 Identities = 21/67 (31%), Positives = 36/67 (53%), Gaps = 3/67 (4%)

Query: 111 LVDPLIRKPDAYTEQLHNEEENEDARSMAAAAASLGGPRANTVLERVEGAQQRWKLQVQE 170
           L+ PL  K D   +QL N+E+ E+ +++    ASL G +   + +R +  + RW   +Q 
Sbjct: 64  LLVPLDVKLDPAVQQLKNQEK-EEMKALNDKFASLIG-KVQALEQRNQLLETRWSF-LQG 120

Query: 171 QRKTVFD 177
           Q   +FD
Sbjct: 121 QDSAIFD 127


>gi|222352179 nuclear factor of kappa light polypeptide gene
           enhancer in B-cells inhibitor-like 1 isoform 4 [Homo
           sapiens]
          Length = 343

 Score = 26.9 bits (58), Expect = 9.8
 Identities = 16/52 (30%), Positives = 25/52 (48%), Gaps = 7/52 (13%)

Query: 121 AYTEQLHNEEENEDARSMAAAAASLGGPRANTVLERVEGAQQRWKLQVQEQR 172
           A++++L  E   +  +    A  S   PRA       EG+ Q W+ Q +EQR
Sbjct: 162 AWSDRLAREHAQKCQQQQREAEGSRRPPRA-------EGSSQSWRQQEEEQR 206


>gi|222352175 nuclear factor of kappa light polypeptide gene
           enhancer in B-cells inhibitor-like 1 isoform 2 [Homo
           sapiens]
          Length = 366

 Score = 26.9 bits (58), Expect = 9.8
 Identities = 16/52 (30%), Positives = 25/52 (48%), Gaps = 7/52 (13%)

Query: 121 AYTEQLHNEEENEDARSMAAAAASLGGPRANTVLERVEGAQQRWKLQVQEQR 172
           A++++L  E   +  +    A  S   PRA       EG+ Q W+ Q +EQR
Sbjct: 185 AWSDRLAREHAQKCQQQQREAEGSRRPPRA-------EGSSQSWRQQEEEQR 229


>gi|222352173 nuclear factor of kappa light polypeptide gene
           enhancer in B-cells inhibitor-like 1 isoform 1 [Homo
           sapiens]
          Length = 381

 Score = 26.9 bits (58), Expect = 9.8
 Identities = 16/52 (30%), Positives = 25/52 (48%), Gaps = 7/52 (13%)

Query: 121 AYTEQLHNEEENEDARSMAAAAASLGGPRANTVLERVEGAQQRWKLQVQEQR 172
           A++++L  E   +  +    A  S   PRA       EG+ Q W+ Q +EQR
Sbjct: 200 AWSDRLAREHAQKCQQQQREAEGSRRPPRA-------EGSSQSWRQQEEEQR 244


>gi|194097352 actinin, alpha 1 isoform c [Homo sapiens]
          Length = 887

 Score = 26.9 bits (58), Expect = 9.8
 Identities = 13/41 (31%), Positives = 21/41 (51%)

Query: 117 RKPDAYTEQLHNEEENEDARSMAAAAASLGGPRANTVLERV 157
           R+  A TE+   ++ NE  R    A A++ GP   T +E +
Sbjct: 613 RRDQALTEEHARQQHNERLRKQFGAQANVIGPWIQTKMEEI 653


>gi|194097350 actinin, alpha 1 isoform a [Homo sapiens]
          Length = 914

 Score = 26.9 bits (58), Expect = 9.8
 Identities = 13/41 (31%), Positives = 21/41 (51%)

Query: 117 RKPDAYTEQLHNEEENEDARSMAAAAASLGGPRANTVLERV 157
           R+  A TE+   ++ NE  R    A A++ GP   T +E +
Sbjct: 613 RRDQALTEEHARQQHNERLRKQFGAQANVIGPWIQTKMEEI 653


>gi|4501891 actinin, alpha 1 isoform b [Homo sapiens]
          Length = 892

 Score = 26.9 bits (58), Expect = 9.8
 Identities = 13/41 (31%), Positives = 21/41 (51%)

Query: 117 RKPDAYTEQLHNEEENEDARSMAAAAASLGGPRANTVLERV 157
           R+  A TE+   ++ NE  R    A A++ GP   T +E +
Sbjct: 613 RRDQALTEEHARQQHNERLRKQFGAQANVIGPWIQTKMEEI 653


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,274,914
Number of Sequences: 37866
Number of extensions: 297238
Number of successful extensions: 974
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 962
Number of HSP's gapped (non-prelim): 24
length of query: 183
length of database: 18,247,518
effective HSP length: 96
effective length of query: 87
effective length of database: 14,612,382
effective search space: 1271277234
effective search space used: 1271277234
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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