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Search of human proteins with 7705981
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7705981 NESH protein isoform 1 [Homo sapiens]
(366 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7705981 NESH protein isoform 1 [Homo sapiens] 748 0.0
gi|206597502 NESH protein isoform 2 [Homo sapiens] 731 0.0
gi|61743946 abl-interactor 1 isoform c [Homo sapiens] 275 4e-74
gi|61743948 abl-interactor 1 isoform d [Homo sapiens] 275 5e-74
gi|109689723 abl interactor 2 [Homo sapiens] 272 4e-73
gi|61743944 abl-interactor 1 isoform b [Homo sapiens] 271 9e-73
gi|61743942 abl-interactor 1 isoform a [Homo sapiens] 207 2e-53
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 76 5e-14
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 76 5e-14
gi|160707881 formin 2 [Homo sapiens] 73 5e-13
gi|56118221 amyloid beta (A4) precursor protein-binding, family ... 66 4e-11
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] 64 2e-10
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] 64 2e-10
gi|51988887 SH3 domain containing ring finger 1 [Homo sapiens] 64 2e-10
gi|33356148 formin-like 1 [Homo sapiens] 63 4e-10
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 62 8e-10
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 62 8e-10
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 62 8e-10
gi|52485606 formin-like 2 [Homo sapiens] 62 8e-10
gi|153792074 proline rich 12 [Homo sapiens] 62 1e-09
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 61 2e-09
gi|47132519 Ras association and pleckstrin homology domains 1 is... 60 2e-09
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 59 5e-09
gi|11386183 WAS protein family, member 2 [Homo sapiens] 59 5e-09
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 59 5e-09
gi|150417989 cyclin K isoform 1 [Homo sapiens] 59 7e-09
gi|163965366 nascent polypeptide-associated complex alpha subuni... 59 7e-09
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 59 9e-09
gi|56549694 enabled homolog isoform a [Homo sapiens] 58 1e-08
gi|39930375 enabled homolog isoform b [Homo sapiens] 58 1e-08
>gi|7705981 NESH protein isoform 1 [Homo sapiens]
Length = 366
Score = 748 bits (1932), Expect = 0.0
Identities = 366/366 (100%), Positives = 366/366 (100%)
Query: 1 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALAS 60
MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALAS
Sbjct: 1 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALAS 60
Query: 61 VAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPP 120
VAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPP
Sbjct: 61 VAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPP 120
Query: 121 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASA 180
GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASA
Sbjct: 121 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASA 180
Query: 181 TLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSS 240
TLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSS
Sbjct: 181 TLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSS 240
Query: 241 LDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPD 300
LDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPD
Sbjct: 241 LDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPD 300
Query: 301 EPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGN 360
EPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGN
Sbjct: 301 EPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGN 360
Query: 361 YVEPSC 366
YVEPSC
Sbjct: 361 YVEPSC 366
>gi|206597502 NESH protein isoform 2 [Homo sapiens]
Length = 360
Score = 731 bits (1887), Expect = 0.0
Identities = 360/366 (98%), Positives = 360/366 (98%), Gaps = 6/366 (1%)
Query: 1 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALAS 60
MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALAS
Sbjct: 1 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALAS 60
Query: 61 VAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPP 120
VAYQVGNLAGHTLRMLDLQGAALRQVEAR MVNMHMEKVARREIGTLATVQRLPP
Sbjct: 61 VAYQVGNLAGHTLRMLDLQGAALRQVEAR------MVNMHMEKVARREIGTLATVQRLPP 114
Query: 121 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASA 180
GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASA
Sbjct: 115 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASA 174
Query: 181 TLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSS 240
TLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSS
Sbjct: 175 TLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSS 234
Query: 241 LDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPD 300
LDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPD
Sbjct: 235 LDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPD 294
Query: 301 EPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGN 360
EPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGN
Sbjct: 295 EPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGN 354
Query: 361 YVEPSC 366
YVEPSC
Sbjct: 355 YVEPSC 360
>gi|61743946 abl-interactor 1 isoform c [Homo sapiens]
Length = 452
Score = 275 bits (704), Expect = 4e-74
Identities = 178/445 (40%), Positives = 239/445 (53%), Gaps = 82/445 (18%)
Query: 1 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALAS 60
MAELQ L E EIP+G+ AL ++ L RVADYCE+NY+QATDKRKALEET A+TTQ+LAS
Sbjct: 1 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
Query: 61 VAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPP 120
VAYQ+ LA + L++LD+Q + LR++E+ ++ + Q V++H EKVARREIG L T +
Sbjct: 61 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
Query: 121 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDL-----STQLSRTGTLSR---KSIK 172
K+IAP N+ Y R+P+++ LDD+GHG+K L + Q +RTGTLSR + K
Sbjct: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
Query: 173 APATPAS--ATLGR--PPRIPEPVHLPVVPD------GRLSAASSASSLAS--------A 214
P+ P S TLGR P + EPV P VP+ RL + S AS +
Sbjct: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240
Query: 215 GSAEGVG--------------GAPTPK----GQAAPPAPP-------------------L 237
GS+ G G PTP G AAP + P
Sbjct: 241 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSS 300
Query: 238 PSSLDPPPPPAAVEVFQRPPTLE--------------ELSPPPPDEELPLPLDLPPPPP- 282
SS P+ F P + PPPP +++P+ D PPPPP
Sbjct: 301 TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSIADSPTPPPPPPPDDIPMFDDSPPPPPP 360
Query: 283 ----LDGDELGLPPPPPGFGPDEPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVT 338
+ +E + + +P+W P +Y+EKVV +Y YT KD+ELSF EG +I V
Sbjct: 361 PPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVI 420
Query: 339 RRYSDGWCEGVSSEGTGFFPGNYVE 363
++ DGW EGV + TG FPGNYVE
Sbjct: 421 KKNDDGWYEGVCNRVTGLFPGNYVE 445
>gi|61743948 abl-interactor 1 isoform d [Homo sapiens]
Length = 476
Score = 275 bits (703), Expect = 5e-74
Identities = 184/469 (39%), Positives = 243/469 (51%), Gaps = 106/469 (22%)
Query: 1 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALAS 60
MAELQ L E EIP+G+ AL ++ L RVADYCE+NY+QATDKRKALEET A+TTQ+LAS
Sbjct: 1 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
Query: 61 VAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPP 120
VAYQ+ LA + L++LD+Q + LR++E+ ++ + Q V++H EKVARREIG L T +
Sbjct: 61 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
Query: 121 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSR---KSIKAPATP 177
K+IAP N+ Y R+P+++ LDD+GHG+K + Q +RTGTLSR + K P+ P
Sbjct: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKHGNNQPARTGTLSRTNPPTQKPPSPP 180
Query: 178 AS--ATLGR--PPRIPEPVHLPVVPD------GRLSAASSASSLAS--------AGSAEG 219
S TLGR P + EPV P VP+ RL + S AS +GS+ G
Sbjct: 181 MSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGG 240
Query: 220 VG--------------GAPTPK----GQAAPPAPP-------------------LPSSLD 242
G PTP G AAP + P SS
Sbjct: 241 SGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGG 300
Query: 243 PPPPPAAVEVFQRPPTLE----------ELSPPPP-----DEELPL-------------- 273
P+ F P + ++PPPP ++PL
Sbjct: 301 YRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADS 360
Query: 274 PLDLPPPPPLD---GDELGLPPPPP----------------GFGPDEPSWVPASYLEKVV 314
P PPPPP D D+ PPPPP + +P+W P +Y+EKVV
Sbjct: 361 PTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVV 420
Query: 315 TLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVE 363
+Y YT KD+ELSF EG +I V ++ DGW EGV + TG FPGNYVE
Sbjct: 421 AIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVE 469
>gi|109689723 abl interactor 2 [Homo sapiens]
Length = 475
Score = 272 bits (695), Expect = 4e-73
Identities = 183/469 (39%), Positives = 240/469 (51%), Gaps = 107/469 (22%)
Query: 1 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALAS 60
MAELQ L E EIP GR AL +++ L RVADYCE+NY+Q+ DK++ALEET A+TTQ+LAS
Sbjct: 1 MAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLAS 60
Query: 61 VAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPP 120
VAY + LA + L+MLD+Q + LR++E+ ++ + Q V++H EKVARREIG L T +
Sbjct: 61 VAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
Query: 121 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSR---KSIKAPATP 177
K+IAP NL Y R+P+++ LDDIGHG+K +STQ + G L R + K P+ P
Sbjct: 121 THKIIAPANLERPVRYIRKPIDYTILDDIGHGVK-VSTQNMKMGGLPRTTPPTQKPPSPP 179
Query: 178 AS--ATLGR--PPRIPEPVHLPVVPDGRL------------------------------- 202
S TLGR P R EPV PVVP+ +
Sbjct: 180 MSGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRTYSSSG 239
Query: 203 -SAASSASSLASAGSAEGVG------GAPTPKGQAAPPAPPL-------PSSLDPPPPPA 248
S S SS +S+ G G PTP + P P+ P+S PP
Sbjct: 240 SSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPGHPVQFYSMNRPASRHTPPTIG 299
Query: 249 AVEVFQRPPTLE--------------------ELSPPPPD-----EELPLP--------- 274
++RPP++ L+PPPP +LPL
Sbjct: 300 GSLPYRRPPSITSQTSLQNQMNGGPFYSQNPVSLAPPPPSILQVTPQLPLMGFVARVQEN 359
Query: 275 -LDLPPPPPLDG----DELGLPPPPP---------------GFGPDEPSWVPASYLEKVV 314
D PPPPP DE PPPPP + ++P W P SYLEKVV
Sbjct: 360 ISDTPPPPPPVEEPVFDESPPPPPPPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKVV 419
Query: 315 TLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVE 363
+Y YT K++ELSF EG +I V ++ DGW EGV + TG FPGNYVE
Sbjct: 420 AIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVE 468
>gi|61743944 abl-interactor 1 isoform b [Homo sapiens]
Length = 481
Score = 271 bits (692), Expect = 9e-73
Identities = 185/474 (39%), Positives = 244/474 (51%), Gaps = 111/474 (23%)
Query: 1 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALAS 60
MAELQ L E EIP+G+ AL ++ L RVADYCE+NY+QATDKRKALEET A+TTQ+LAS
Sbjct: 1 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
Query: 61 VAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPP 120
VAYQ+ LA + L++LD+Q + LR++E+ ++ + Q V++H EKVARREIG L T +
Sbjct: 61 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
Query: 121 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDL-----STQLSRTGTLSR---KSIK 172
K+IAP N+ Y R+P+++ LDD+GHG+K L + Q +RTGTLSR + K
Sbjct: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
Query: 173 APATPAS--ATLGR--PPRIPEPVHLPVVPD------GRLSAASSASSLAS--------A 214
P+ P S TLGR P + EPV P VP+ RL + S AS +
Sbjct: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240
Query: 215 GSAEGVG--------------GAPTPK----GQAAPPAPP-------------------L 237
GS+ G G PTP G AAP + P
Sbjct: 241 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSS 300
Query: 238 PSSLDPPPPPAAVEVFQRPPTLE----------ELSPPPP-----DEELPL--------- 273
SS P+ F P + ++PPPP ++PL
Sbjct: 301 TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQE 360
Query: 274 -----PLDLPPPPPLD---GDELGLPPPPP----------------GFGPDEPSWVPASY 309
P PPPPP D D+ PPPPP + +P+W P +Y
Sbjct: 361 NIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNY 420
Query: 310 LEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVE 363
+EKVV +Y YT KD+ELSF EG +I V ++ DGW EGV + TG FPGNYVE
Sbjct: 421 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVE 474
>gi|61743942 abl-interactor 1 isoform a [Homo sapiens]
Length = 508
Score = 207 bits (526), Expect = 2e-53
Identities = 131/298 (43%), Positives = 176/298 (59%), Gaps = 23/298 (7%)
Query: 1 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALAS 60
MAELQ L E EIP+G+ AL ++ L RVADYCE+NY+QATDKRKALEET A+TTQ+LAS
Sbjct: 1 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 60
Query: 61 VAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPP 120
VAYQ+ LA + L++LD+Q + LR++E+ ++ + Q V++H EKVARREIG L T +
Sbjct: 61 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 120
Query: 121 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDL-----STQLSRTGTLSR---KSIK 172
K+IAP N+ Y R+P+++ LDD+GHG+K L + Q +RTGTLSR + K
Sbjct: 121 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 180
Query: 173 APATPAS--ATLGR--PPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAP-TPK 227
P+ P S TLGR P + EPV P VP+ +++ + S S G + P T
Sbjct: 181 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 240
Query: 228 GQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTL--EELSPPPPDEELPLPLDLPPPPPL 283
G + S P AV PPT+ E +S PPP PP PPL
Sbjct: 241 GSSGGSGSRENSGSSSIGIPIAVPT-PSPPTIGPENISVPPPS-------GAPPAPPL 290
Score = 114 bits (285), Expect = 1e-25
Identities = 77/216 (35%), Positives = 108/216 (50%), Gaps = 30/216 (13%)
Query: 173 APATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQ-AA 231
AP P S + P P + + ++S +S +S S+G G P+ Q +A
Sbjct: 291 APLLPVSTVIAAPGSAPGSQYGTMTR--QISRHNSTTSSTSSG---GYRRTPSVTAQFSA 345
Query: 232 PP---APPLPS----SLDPPPPPAAVEVFQRPPT------LEELS------PPPPDEELP 272
P PL S S+ PPPPP Q P T E ++ PPPP +++P
Sbjct: 346 QPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIP 405
Query: 273 LPLDLPPPPP-----LDGDELGLPPPPPGFGPDEPSWVPASYLEKVVTLYPYTSQKDNEL 327
+ D PPPPP + +E + + +P+W P +Y+EKVV +Y YT KD+EL
Sbjct: 406 MFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDEL 465
Query: 328 SFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVE 363
SF EG +I V ++ DGW EGV + TG FPGNYVE
Sbjct: 466 SFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVE 501
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 75.9 bits (185), Expect = 5e-14
Identities = 52/134 (38%), Positives = 60/134 (44%), Gaps = 31/134 (23%)
Query: 174 PATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPP 233
P AT+ PP +PE V +P S SSL P G A PP
Sbjct: 634 PPLSGDATIPPPPPLPEGVGIP-----------SPSSL--------------PGGTAIPP 668
Query: 234 APPLPSS--LDPPPPP--AAVEVFQRPPTLE-ELSPPPPDEELPLPLDLPPPPPLDGDEL 288
PPLP S + PPPPP + + PP L E PPP LP +PPPPP G
Sbjct: 669 PPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGP- 727
Query: 289 GLPPPPPGFGPDEP 302
G+PPPPPG G P
Sbjct: 728 GIPPPPPGMGMPPP 741
Score = 67.4 bits (163), Expect = 2e-11
Identities = 47/138 (34%), Positives = 53/138 (38%), Gaps = 12/138 (8%)
Query: 171 IKAPATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQA 230
I P P +T PP P P P L SS S + P G A
Sbjct: 587 IPPPPAPGDSTTPPPPPPPPP------PPPPLPGGVCISSPPSLPGGTAISPPPPLSGDA 640
Query: 231 A-PPAPPLPSSLDPPPP---PAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGD 286
PP PPLP + P P P + PP PPP LP +PPPPP
Sbjct: 641 TIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPG 700
Query: 287 ELGLPPPPPGF--GPDEP 302
E G+PPPPP GP P
Sbjct: 701 EAGMPPPPPPLPGGPGIP 718
Score = 64.7 bits (156), Expect = 1e-10
Identities = 43/162 (26%), Positives = 65/162 (40%), Gaps = 18/162 (11%)
Query: 148 DIGHGIKDLSTQLSRTGTLSRKSIKAPATPASATLGRPPRIPEPVHLPVVPDGRLSAASS 207
D+ + L+ ++++ + K A+ ++A + PP +P +P P
Sbjct: 527 DLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPP----LPGD 582
Query: 208 ASSLASAGSAEGVGGAPTPKGQAAPPAPPLP--------------SSLDPPPPPAAVEVF 253
+ ++ A G P P PP PPLP +++ PPPP +
Sbjct: 583 SGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATI 642
Query: 254 QRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPP 295
PP L E P LP +PPPPPL G PPPPP
Sbjct: 643 PPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPP 684
Score = 60.1 bits (144), Expect = 3e-09
Identities = 42/110 (38%), Positives = 48/110 (43%), Gaps = 15/110 (13%)
Query: 211 LASAGSAEGVGGAPTPKGQAAPPAPPLP--SSLDPPPPPAAVEVFQRPPTLEELSPPPP- 267
+AS +A P PPAPPLP S PPPPA + PP PPPP
Sbjct: 553 MASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPL 612
Query: 268 --------DEELPLPLDLPPPPPLDGDELGLPPPPP---GFGPDEPSWVP 306
LP + PPPPL GD +PPPPP G G PS +P
Sbjct: 613 PGGVCISSPPSLPGGTAISPPPPLSGDAT-IPPPPPLPEGVGIPSPSSLP 661
Score = 38.1 bits (87), Expect = 0.013
Identities = 33/125 (26%), Positives = 44/125 (35%), Gaps = 21/125 (16%)
Query: 171 IKAPAT-PASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPK-- 227
I +P++ P + PP +P +P P +A G+ P P
Sbjct: 654 IPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPG 713
Query: 228 GQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDE 287
G PP PP P PPPP + + PPPP P +P P L
Sbjct: 714 GPGIPPPPPFPGGPGIPPPPPGMGM-----------PPPP----PFGFGVPAAPVL---P 755
Query: 288 LGLPP 292
GL P
Sbjct: 756 FGLTP 760
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 75.9 bits (185), Expect = 5e-14
Identities = 52/134 (38%), Positives = 60/134 (44%), Gaps = 31/134 (23%)
Query: 174 PATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPP 233
P AT+ PP +PE V +P S SSL P G A PP
Sbjct: 643 PPLSGDATIPPPPPLPEGVGIP-----------SPSSL--------------PGGTAIPP 677
Query: 234 APPLPSS--LDPPPPP--AAVEVFQRPPTLE-ELSPPPPDEELPLPLDLPPPPPLDGDEL 288
PPLP S + PPPPP + + PP L E PPP LP +PPPPP G
Sbjct: 678 PPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGP- 736
Query: 289 GLPPPPPGFGPDEP 302
G+PPPPPG G P
Sbjct: 737 GIPPPPPGMGMPPP 750
Score = 67.4 bits (163), Expect = 2e-11
Identities = 47/138 (34%), Positives = 53/138 (38%), Gaps = 12/138 (8%)
Query: 171 IKAPATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQA 230
I P P +T PP P P P L SS S + P G A
Sbjct: 596 IPPPPAPGDSTTPPPPPPPPP------PPPPLPGGVCISSPPSLPGGTAISPPPPLSGDA 649
Query: 231 A-PPAPPLPSSLDPPPP---PAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGD 286
PP PPLP + P P P + PP PPP LP +PPPPP
Sbjct: 650 TIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPG 709
Query: 287 ELGLPPPPPGF--GPDEP 302
E G+PPPPP GP P
Sbjct: 710 EAGMPPPPPPLPGGPGIP 727
Score = 64.7 bits (156), Expect = 1e-10
Identities = 43/162 (26%), Positives = 65/162 (40%), Gaps = 18/162 (11%)
Query: 148 DIGHGIKDLSTQLSRTGTLSRKSIKAPATPASATLGRPPRIPEPVHLPVVPDGRLSAASS 207
D+ + L+ ++++ + K A+ ++A + PP +P +P P
Sbjct: 536 DLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPP----LPGD 591
Query: 208 ASSLASAGSAEGVGGAPTPKGQAAPPAPPLP--------------SSLDPPPPPAAVEVF 253
+ ++ A G P P PP PPLP +++ PPPP +
Sbjct: 592 SGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATI 651
Query: 254 QRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPP 295
PP L E P LP +PPPPPL G PPPPP
Sbjct: 652 PPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPP 693
Score = 60.1 bits (144), Expect = 3e-09
Identities = 42/110 (38%), Positives = 48/110 (43%), Gaps = 15/110 (13%)
Query: 211 LASAGSAEGVGGAPTPKGQAAPPAPPLP--SSLDPPPPPAAVEVFQRPPTLEELSPPPP- 267
+AS +A P PPAPPLP S PPPPA + PP PPPP
Sbjct: 562 MASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPL 621
Query: 268 --------DEELPLPLDLPPPPPLDGDELGLPPPPP---GFGPDEPSWVP 306
LP + PPPPL GD +PPPPP G G PS +P
Sbjct: 622 PGGVCISSPPSLPGGTAISPPPPLSGDAT-IPPPPPLPEGVGIPSPSSLP 670
Score = 38.1 bits (87), Expect = 0.013
Identities = 33/125 (26%), Positives = 44/125 (35%), Gaps = 21/125 (16%)
Query: 171 IKAPAT-PASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPK-- 227
I +P++ P + PP +P +P P +A G+ P P
Sbjct: 663 IPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPG 722
Query: 228 GQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDE 287
G PP PP P PPPP + + PPPP P +P P L
Sbjct: 723 GPGIPPPPPFPGGPGIPPPPPGMGM-----------PPPP----PFGFGVPAAPVL---P 764
Query: 288 LGLPP 292
GL P
Sbjct: 765 FGLTP 769
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 72.8 bits (177), Expect = 5e-13
Identities = 53/142 (37%), Positives = 60/142 (42%), Gaps = 12/142 (8%)
Query: 174 PATPASATLGRPPRIPEP-VHLPVVPDGRLSAASSASSLASAG-----SAEGVGGAPTPK 227
P P G PP P P +P P + L AG GVG P P
Sbjct: 1053 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPP 1112
Query: 228 --GQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLP-LDLPPPPPLD 284
G PP PPLP + PPPPP PP L + PPP PLP +PPPPPL
Sbjct: 1113 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPP---PLPGAGIPPPPPLP 1169
Query: 285 GDELGLPPPPPGFGPDEPSWVP 306
G + PPP PG G P +P
Sbjct: 1170 GAGIPPPPPLPGVGIPPPPPLP 1191
Score = 72.0 bits (175), Expect = 8e-13
Identities = 52/143 (36%), Positives = 61/143 (42%), Gaps = 13/143 (9%)
Query: 174 PATPASATLGRPPR----IPEPVHLP---VVPDGRLSAASSASSLASAGSAEGVGGAPTP 226
P P + L PP IP P LP + P L A G+ G+ P
Sbjct: 924 PPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGA--GIPPPPPL 981
Query: 227 KGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLP-LDLPPPPPLDG 285
G PP PPLP + PPPPP PP L PPP PLP +PPPPPL G
Sbjct: 982 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP---PLPGAGIPPPPPLPG 1038
Query: 286 DELGLPPPPPGFGPDEPSWVPAS 308
+ PPP PG G P +P +
Sbjct: 1039 AGIPPPPPLPGAGIPPPPPLPGA 1061
Score = 70.5 bits (171), Expect = 2e-12
Identities = 52/143 (36%), Positives = 61/143 (42%), Gaps = 13/143 (9%)
Query: 174 PATPASATLGRPPR----IPEPVHLP---VVPDGRLSAASSASSLASAGSAEGVGGAPTP 226
P P +A PP IP P LP + P L A G+ G+ P
Sbjct: 946 PPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGA--GIPPPPPL 1003
Query: 227 KGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLP-LDLPPPPPLDG 285
G PP PPLP + PPPPP PP L PPP PLP +PPPPPL G
Sbjct: 1004 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP---PLPGAGIPPPPPLPG 1060
Query: 286 DELGLPPPPPGFGPDEPSWVPAS 308
+ PPP PG G P +P +
Sbjct: 1061 AGIPPPPPLPGAGIPPPPPLPGA 1083
Score = 70.5 bits (171), Expect = 2e-12
Identities = 51/143 (35%), Positives = 61/143 (42%), Gaps = 13/143 (9%)
Query: 174 PATPASATLGRPPR----IPEPVHLP---VVPDGRLSAASSASSLASAGSAEGVGGAPTP 226
P P + PP IP P LP + P L A G+ G+ P
Sbjct: 1001 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA--GIPPPPPL 1058
Query: 227 KGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLP-LDLPPPPPLDG 285
G PP PPLP + PPPPP PP L PPP PLP + +PPPPPL G
Sbjct: 1059 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP---PLPGVGIPPPPPLPG 1115
Query: 286 DELGLPPPPPGFGPDEPSWVPAS 308
+ PPP PG G P +P +
Sbjct: 1116 AGIPPPPPLPGAGIPPPPPLPGA 1138
Score = 70.1 bits (170), Expect = 3e-12
Identities = 49/138 (35%), Positives = 60/138 (43%), Gaps = 12/138 (8%)
Query: 174 PATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPK--GQAA 231
P P++A + +PP + LP P A + G G P P G
Sbjct: 889 PTLPSTA-IPQPPPLQGTEMLPPPPPPLPGAG-----IPPPPPLPGAGILPLPPLPGAGI 942
Query: 232 PPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLP-LDLPPPPPLDGDELGL 290
PP PPLP + PPPPP PP L PPP PLP +PPPPPL G +
Sbjct: 943 PPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPP---PLPGAGIPPPPPLPGAGIPP 999
Query: 291 PPPPPGFGPDEPSWVPAS 308
PPP PG G P +P +
Sbjct: 1000 PPPLPGAGIPPPPPLPGA 1017
Score = 69.3 bits (168), Expect = 5e-12
Identities = 52/137 (37%), Positives = 60/137 (43%), Gaps = 13/137 (9%)
Query: 174 PATPASATLGRPPRIPEP-VHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAP 232
P P G PP P P V +P P + L AG + P G P
Sbjct: 1086 PPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAG----IPPPPPLPGAGIP 1141
Query: 233 PAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLP-LDLPPPPPLDGDELGLP 291
P PPLP PPPPP PP L PPP PLP + +PPPPPL G +G+P
Sbjct: 1142 PPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPP---PLPGVGIPPPPPLPG--VGIP 1196
Query: 292 PPP--PGFGPDEPSWVP 306
PPP PG G P +P
Sbjct: 1197 PPPPLPGAGIPPPPPLP 1213
Score = 68.2 bits (165), Expect = 1e-11
Identities = 40/93 (43%), Positives = 47/93 (50%), Gaps = 8/93 (8%)
Query: 219 GVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLP-LDL 277
G+ P G PP PPLP + PPPPP PP L PPP PLP +
Sbjct: 1117 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPP---PLPGAGI 1173
Query: 278 PPPPPLDGDELGLPPPP--PGFGPDEPSWVPAS 308
PPPPPL G +G+PPPP PG G P +P +
Sbjct: 1174 PPPPPLPG--VGIPPPPPLPGVGIPPPPPLPGA 1204
Score = 60.1 bits (144), Expect = 3e-09
Identities = 49/143 (34%), Positives = 58/143 (40%), Gaps = 39/143 (27%)
Query: 174 PATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPP 233
P P G PP P P + + P L A G+ P G PP
Sbjct: 1130 PPPPPLPGAGIPPPPPLP-RVGIPPPPPLPGA-------------GIPPPPPLPGAGIPP 1175
Query: 234 APPLPS-SLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLP-LDLPPPPPLDGDELGLP 291
PPLP + PPPP V + PPPP PLP +PPPPPL G +G+P
Sbjct: 1176 PPPLPGVGIPPPPPLPGVGI-----------PPPP----PLPGAGIPPPPPLPG--MGIP 1218
Query: 292 P------PPPGFGPDEPSWVPAS 308
P PPPG G P +P S
Sbjct: 1219 PAPAPPLPPPGTGIPPPPLLPVS 1241
Score = 50.1 bits (118), Expect = 3e-06
Identities = 48/152 (31%), Positives = 66/152 (43%), Gaps = 17/152 (11%)
Query: 169 KSIKAPATPASA--TLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTP 226
+SI P P S + G+ +P H + + + S S SS A S P P
Sbjct: 805 QSISQPPPPPSLLWSAGQGQPGSQPPH-SISTEFQTSHEHSVSS-AFKNSCNIPSPPPLP 862
Query: 227 KGQAAPPAPPLPSSLDPPPPPAAVEV-------FQRPPTLE--ELSPPPPDEELPLP-LD 276
+++ P L PPPP + V +PP L+ E+ PPPP PLP
Sbjct: 863 CTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPP---PLPGAG 919
Query: 277 LPPPPPLDGDELGLPPPPPGFGPDEPSWVPAS 308
+PPPPPL G + PP PG G P +P +
Sbjct: 920 IPPPPPLPGAGILPLPPLPGAGIPPPPPLPGA 951
Score = 48.5 bits (114), Expect = 9e-06
Identities = 37/102 (36%), Positives = 44/102 (43%), Gaps = 21/102 (20%)
Query: 228 GQAAPPAPP----------LPSSLDPPPPP-AAVEVFQRPPTL---EELSPPPP---DEE 270
G P PP LPS+ P PPP E+ PP + PPPP
Sbjct: 872 GLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGI 931
Query: 271 LPLP----LDLPPPPPLDGDELGLPPPPPGFGPDEPSWVPAS 308
LPLP +PPPPPL G + PPP PG G P +P +
Sbjct: 932 LPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGA 973
Score = 33.1 bits (74), Expect = 0.40
Identities = 37/113 (32%), Positives = 43/113 (38%), Gaps = 22/113 (19%)
Query: 174 PATPASATLGRPPRIPEP-VHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAP 232
P P +G PP P P V +P P + + G+G P P AP
Sbjct: 1174 PPPPPLPGVGIPPPPPLPGVGIPPPPP------LPGAGIPPPPPLPGMGIPPAP----AP 1223
Query: 233 PAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPL---DLPPPPP 282
P PP P + PPPP V PP L P LP P LPPP P
Sbjct: 1224 PLPP-PGTGIPPPPLLPV---SGPPLL----PQVGSSTLPTPQVCGFLPPPLP 1268
>gi|56118221 amyloid beta (A4) precursor protein-binding, family B,
member 1 interacting protein [Homo sapiens]
Length = 666
Score = 66.2 bits (160), Expect = 4e-11
Identities = 47/156 (30%), Positives = 58/156 (37%), Gaps = 21/156 (13%)
Query: 144 GCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASATLGRPPRIPEPVHLPVVPDGRLS 203
G + H + + + R S+ A + R P P+ P P R S
Sbjct: 467 GQIPQATHSVSAVLQEAQRHAETSKDKKPALGNHHDPAVPRAPHAPKSSLPPPPPVRRSS 526
Query: 204 AASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELS 263
S + + G GG P P PP PP P DP EL
Sbjct: 527 DTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLDDP-----------------ELP 569
Query: 264 PPPPDEELPLPLDLPPPPP----LDGDELGLPPPPP 295
PPPPD P P +PPPPP + G EL PPPPP
Sbjct: 570 PPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPP 605
Score = 35.4 bits (80), Expect = 0.081
Identities = 15/28 (53%), Positives = 18/28 (64%)
Query: 260 EELSPPPPDEELPLPLDLPPPPPLDGDE 287
++L PPP D L LPL PPP PL +E
Sbjct: 126 DDLPPPPADPVLDLPLPPPPPEPLSQEE 153
Score = 34.3 bits (77), Expect = 0.18
Identities = 68/257 (26%), Positives = 86/257 (33%), Gaps = 44/257 (17%)
Query: 27 LRVADYCE---DNYVQATDKRK-ALEETMAFTTQALASVAYQVGNLAGHTLRMLDLQGAA 82
+R+A Y + DNY +A K A T T A A G G T
Sbjct: 414 IRIAKYGKTLYDNYQRAVAKAGLASRWTNLGTVNAAAPAQPSTGPKTGTTQ-----PNGQ 468
Query: 83 LRQVEARVSTLGQMVNMHME--KVARREIGTL--ATVQRLPPGQKVIAPENLPPLTPYCR 138
+ Q VS + Q H E K + +G V R P K +LPP P R
Sbjct: 469 IPQATHSVSAVLQEAQRHAETSKDKKPALGNHHDPAVPRAPHAPK----SSLPPPPPVRR 524
Query: 139 RPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASATLGRPPRIPEPVHLPVVP 198
G +T L GT + AP PP + +P P P
Sbjct: 525 SSDTSG----------SPATPLKAKGT-GGGGLPAPPDDFLPPPPPPPPLDDPELPPPPP 573
Query: 199 DGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAP---PLPSSLDPPPPPAAVEVFQR 255
D S G+ G+ P PPAP P+P S PPP V +R
Sbjct: 574 DFMEPPPDFVPP--PPPSYAGIAGSELPPPPPPPPAPAPAPVPDSARPPP-----AVAKR 626
Query: 256 PPTLEELSPPPPDEELP 272
PP PP +E P
Sbjct: 627 PPV------PPKRQENP 637
Score = 30.8 bits (68), Expect = 2.0
Identities = 13/20 (65%), Positives = 14/20 (70%)
Query: 276 DLPPPPPLDGDELGLPPPPP 295
DLPPPP +L LPPPPP
Sbjct: 127 DLPPPPADPVLDLPLPPPPP 146
>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
Length = 1240
Score = 64.3 bits (155), Expect = 2e-10
Identities = 70/250 (28%), Positives = 97/250 (38%), Gaps = 49/250 (19%)
Query: 81 AALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQR-----LPPGQKVIAPENLPPLTP 135
A L +A+ TL ++V + R L + L Q+ +P+N P
Sbjct: 322 AVLLASDAQECTLEEVVERLLSVKGRPRPSPLVKAHKSVQANLDQSQRGSSPQNTTTPKP 381
Query: 136 YC--RRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASATL----GRPPRIP 189
++P + + H + ++S+ L +++ P P L PP P
Sbjct: 382 SVEGQQPAAAAACEPVDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPP 441
Query: 190 EPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPS--SLDPPPPP 247
P LP V G PT APP PPLP ++ PP PP
Sbjct: 442 PPPPLPSV---------------------GAKALPT-----APPPPPLPGLGAMAPPAPP 475
Query: 248 AAVEVFQRPPTLEELSPPPPDEELPLP-LDLPPPPP--LDGDELGLPPPPPGFGPDEPSW 304
+ P + E L PPPP PLP L PPPPP L G G PPPPP P S
Sbjct: 476 LPPPL---PGSCEFLPPPPP----PLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSP 528
Query: 305 VPASYLEKVV 314
A +E+V+
Sbjct: 529 PVAGGMEEVI 538
>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
Length = 1249
Score = 64.3 bits (155), Expect = 2e-10
Identities = 70/250 (28%), Positives = 97/250 (38%), Gaps = 49/250 (19%)
Query: 81 AALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQR-----LPPGQKVIAPENLPPLTP 135
A L +A+ TL ++V + R L + L Q+ +P+N P
Sbjct: 322 AVLLASDAQECTLEEVVERLLSVKGRPRPSPLVKAHKSVQANLDQSQRGSSPQNTTTPKP 381
Query: 136 YC--RRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASATL----GRPPRIP 189
++P + + H + ++S+ L +++ P P L PP P
Sbjct: 382 SVEGQQPAAAAACEPVDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPP 441
Query: 190 EPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPS--SLDPPPPP 247
P LP V G PT APP PPLP ++ PP PP
Sbjct: 442 PPPPLPSV---------------------GAKALPT-----APPPPPLPGLGAMAPPAPP 475
Query: 248 AAVEVFQRPPTLEELSPPPPDEELPLP-LDLPPPPP--LDGDELGLPPPPPGFGPDEPSW 304
+ P + E L PPPP PLP L PPPPP L G G PPPPP P S
Sbjct: 476 LPPPL---PGSCEFLPPPPP----PLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSP 528
Query: 305 VPASYLEKVV 314
A +E+V+
Sbjct: 529 PVAGGMEEVI 538
>gi|51988887 SH3 domain containing ring finger 1 [Homo sapiens]
Length = 888
Score = 63.9 bits (154), Expect = 2e-10
Identities = 56/203 (27%), Positives = 78/203 (38%), Gaps = 11/203 (5%)
Query: 165 TLSRKSIKAPATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAP 224
T++ KS +A S + P I LS S ++ S G+ P
Sbjct: 309 TMANKSSQASQNRHSMEISPPVLISSSNPTAAARISELSGLSCSAPSQVHISTTGLIVTP 368
Query: 225 TPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLD 284
P P PS P P + P L PPPP + PP
Sbjct: 369 PPSS----PVTTGPSFTFPSDVPYQAALGTLNPPL----PPPPLLAATVLASTPPGATAA 420
Query: 285 GDELGLPPPPPGFGPDEPSWV-PASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSD 343
G+ P P D+ + + P + V +YPYT +K++EL +G + V R D
Sbjct: 421 AAAAGMGPRPMAGSTDQIAHLRPQTRPSVYVAIYPYTPRKEDELELRKGEMFLVFERCQD 480
Query: 344 GWCEGVS--SEGTGFFPGNYVEP 364
GW +G S + G FPGNYV P
Sbjct: 481 GWFKGTSMHTSKIGVFPGNYVAP 503
Score = 43.5 bits (101), Expect = 3e-04
Identities = 48/175 (27%), Positives = 65/175 (37%), Gaps = 33/175 (18%)
Query: 201 RLSAASSASSLASAGSAE----GVGGAPTPKGQAAPPAPPLPSSLDPPPPPA------AV 250
R+S +S + GSAE G G P G A P D P A A
Sbjct: 733 RVSPPASPTLEVELGSAELPLQGAVGPELPPGGGHGRAGSCPVDGDGPVTTAVAGAALAQ 792
Query: 251 EVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPDEPSWVPASYL 310
+ F R + + + P + PPP LG P P
Sbjct: 793 DAFHRKASSLDSAVP-----------IAPPPRQACSSLG-----PVLNESRPV---VCER 833
Query: 311 EKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEG--TGFFPGNYVE 363
+VV YP Q + EL EG ++ V ++ DGW +G TG FPG++VE
Sbjct: 834 HRVVVSYP--PQSEAELELKEGDIVFVHKKREDGWFKGTLQRNGKTGLFPGSFVE 886
Score = 41.6 bits (96), Expect = 0.001
Identities = 23/72 (31%), Positives = 34/72 (47%), Gaps = 4/72 (5%)
Query: 296 GFGPDEPSWVPA----SYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSS 351
G P SW P L LY Y ++ +L FS+G +I + R+ + W G +
Sbjct: 118 GQQPRVQSWSPPVRGIPQLPCAKALYNYEGKEPGDLKFSKGDIIILRRQVDENWYHGEVN 177
Query: 352 EGTGFFPGNYVE 363
GFFP N+V+
Sbjct: 178 GIHGFFPTNFVQ 189
Score = 36.2 bits (82), Expect = 0.048
Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 22/79 (27%)
Query: 290 LPPPPPGFGPDEPSWVPASYLEKVVTLYPYTSQKDNE-----LSFSEGTVICVTRRYSDG 344
LP PPP + LY + KD E L F++ V+ V RR +
Sbjct: 194 LPQPPP----------------QCKALYDF-EVKDKEADKDCLPFAKDDVLTVIRRVDEN 236
Query: 345 WCEGVSSEGTGFFPGNYVE 363
W EG+ ++ G FP +YVE
Sbjct: 237 WAEGMLADKIGIFPISYVE 255
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 63.2 bits (152), Expect = 4e-10
Identities = 44/114 (38%), Positives = 57/114 (50%), Gaps = 23/114 (20%)
Query: 195 PVVPDGRLSAASSASSLASAGSAEG----VGGAPTPKG---QAAPPAPPLPSSLDPPP-P 246
P VP G S + ++ + G+A + G P+P+ A P APPLP S +PPP P
Sbjct: 519 PGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAP 578
Query: 247 PAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPD 300
P ++ PP PPPP + P+P PPPPP PPPPPG PD
Sbjct: 579 PLPGDLPPPPPP----PPPPPGTDGPVP---PPPPP--------PPPPPGGPPD 617
Score = 58.5 bits (140), Expect = 9e-09
Identities = 60/196 (30%), Positives = 73/196 (37%), Gaps = 47/196 (23%)
Query: 153 IKDLSTQLSRTGTLSRKSIKA--PATPASATLGRPPRIPEPVHLPVVPDGRLSA------ 204
I +L QLS+ +RK ++ S +G R PEP P R SA
Sbjct: 426 IAELEKQLSQ----ARKELETLRERFSESTAMGASRRPPEPEKAPPAAPTRPSALELKVE 481
Query: 205 ----------------ASSASSLASAGSAEGVGGAPTP-------KGQAAPPAPPLPSSL 241
A S L A + G APTP AP A P P +
Sbjct: 482 ELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAA 541
Query: 242 DPPPPP--AAVEVFQRPPTLEELSPP-------PPDEELP--LPLDLPPPPPLDGDELGL 290
PPPPP + PP+ +PP PP LP LP PPPPP G + +
Sbjct: 542 PPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPV 601
Query: 291 PPPPPGFGPDEPSWVP 306
PPPPP P P P
Sbjct: 602 PPPPPP-PPPPPGGPP 616
Score = 52.8 bits (125), Expect = 5e-07
Identities = 44/119 (36%), Positives = 48/119 (40%), Gaps = 31/119 (26%)
Query: 173 APATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAP 232
APA + PP P P LP + SA A L G+P P P
Sbjct: 531 APAAEPAPGAAPPPPPPLP-GLPSPQEAPPSAPPQAPPLP---------GSPEP-----P 575
Query: 233 PAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDG--DELG 289
PAPPLP L PPPPP PP + PPPP PPPPP G D LG
Sbjct: 576 PAPPLPGDLPPPPPPPPP-----PPGTDGPVPPPPP---------PPPPPPGGPPDALG 620
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 62.0 bits (149), Expect = 8e-10
Identities = 43/105 (40%), Positives = 52/105 (49%), Gaps = 11/105 (10%)
Query: 217 AEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPP--PDEELPLP 274
+E GG+P P + P PP P L+PPPPP+ PP LE LSPP +P P
Sbjct: 155 SEPPGGSPLPSPPSTAPPPP-PLLLEPPPPPSMAP--PPPPVLEALSPPHTLSSPSIPTP 211
Query: 275 LD-LPPPPPLDGDELGLPPPPPGFGPDEPSWVPASYLEKVVTLYP 318
D +PP PPL PPPPP P P+ PAS L+P
Sbjct: 212 PDFIPPAPPL---AFLAPPPPPVPAPAPPA--PASPHTVGTRLFP 251
Score = 45.1 bits (105), Expect = 1e-04
Identities = 51/165 (30%), Positives = 62/165 (37%), Gaps = 39/165 (23%)
Query: 172 KAPATPASATLGRPPRIPEP--VHL----PVVPD--------GRLSAASSASSLA--SAG 215
+AP AT P R+P P H+ V PD G L A + AS S
Sbjct: 322 EAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQS 381
Query: 216 SAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPP------PDE 269
A+ G P P PPAPPLP PP PPAA + P ++ + PP P
Sbjct: 382 QADERAGTPPPAPPLPPPAPPLPPPA-PPLPPAAPPL----PCAQKAAHPPAGFTKTPKS 436
Query: 270 ELPLPLDLPPPPPLDGDELGLPPPPPGFGPDEP-SWVPASYLEKV 313
P L P P PP P P W S +EK+
Sbjct: 437 SSPA---LKPKPN--------PPSPENTASSAPVDWRDPSQMEKL 470
Score = 40.0 bits (92), Expect = 0.003
Identities = 39/120 (32%), Positives = 43/120 (35%), Gaps = 32/120 (26%)
Query: 199 DGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPP---------APPLPSSLDPPPPPAA 249
+G L SS L + + P P G A P PLPS PPP
Sbjct: 116 NGNLRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPP-- 173
Query: 250 VEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPL-----DGDELGLP--PPPPGFGPDEP 302
PP L L PPPP P PPPPP+ L P P PP F P P
Sbjct: 174 ------PPLL--LEPPPP------PSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAP 219
Score = 32.3 bits (72), Expect = 0.69
Identities = 34/108 (31%), Positives = 42/108 (38%), Gaps = 23/108 (21%)
Query: 176 TPASATLGRPPRIPEPVHLPVV---PDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAP 232
+P S PP + EP P + P L A S +L+S PTP P
Sbjct: 165 SPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPS-------IPTPP-DFIP 216
Query: 233 PAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPP 280
PAPPL + L PPPPP +PP P + L PP
Sbjct: 217 PAPPL-AFLAPPPPPVPA-----------PAPPAPASPHTVGTRLFPP 252
Score = 31.6 bits (70), Expect = 1.2
Identities = 25/78 (32%), Positives = 28/78 (35%), Gaps = 10/78 (12%)
Query: 232 PPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPP----DEELPLPL------DLPPPP 281
P PLP S PP P+ + E+ PPPP D E P P PP
Sbjct: 955 PQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPR 1014
Query: 282 PLDGDELGLPPPPPGFGP 299
D LP PG P
Sbjct: 1015 NNYSDLRQLPNAGPGAPP 1032
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 62.0 bits (149), Expect = 8e-10
Identities = 43/105 (40%), Positives = 52/105 (49%), Gaps = 11/105 (10%)
Query: 217 AEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPP--PDEELPLP 274
+E GG+P P + P PP P L+PPPPP+ PP LE LSPP +P P
Sbjct: 155 SEPPGGSPLPSPPSTAPPPP-PLLLEPPPPPSMAP--PPPPVLEALSPPHTLSSPSIPTP 211
Query: 275 LD-LPPPPPLDGDELGLPPPPPGFGPDEPSWVPASYLEKVVTLYP 318
D +PP PPL PPPPP P P+ PAS L+P
Sbjct: 212 PDFIPPAPPL---AFLAPPPPPVPAPAPPA--PASPHTVGTRLFP 251
Score = 45.1 bits (105), Expect = 1e-04
Identities = 51/165 (30%), Positives = 62/165 (37%), Gaps = 39/165 (23%)
Query: 172 KAPATPASATLGRPPRIPEP--VHL----PVVPD--------GRLSAASSASSLA--SAG 215
+AP AT P R+P P H+ V PD G L A + AS S
Sbjct: 322 EAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQS 381
Query: 216 SAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPP------PDE 269
A+ G P P PPAPPLP PP PPAA + P ++ + PP P
Sbjct: 382 QADERAGTPPPAPPLPPPAPPLPPPA-PPLPPAAPPL----PCAQKAAHPPAGFTKTPKS 436
Query: 270 ELPLPLDLPPPPPLDGDELGLPPPPPGFGPDEP-SWVPASYLEKV 313
P L P P PP P P W S +EK+
Sbjct: 437 SSPA---LKPKPN--------PPSPENTASSAPVDWRDPSQMEKL 470
Score = 40.0 bits (92), Expect = 0.003
Identities = 39/120 (32%), Positives = 43/120 (35%), Gaps = 32/120 (26%)
Query: 199 DGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPP---------APPLPSSLDPPPPPAA 249
+G L SS L + + P P G A P PLPS PPP
Sbjct: 116 NGNLRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPP-- 173
Query: 250 VEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPL-----DGDELGLP--PPPPGFGPDEP 302
PP L L PPPP P PPPPP+ L P P PP F P P
Sbjct: 174 ------PPLL--LEPPPP------PSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAP 219
Score = 32.3 bits (72), Expect = 0.69
Identities = 34/108 (31%), Positives = 42/108 (38%), Gaps = 23/108 (21%)
Query: 176 TPASATLGRPPRIPEPVHLPVV---PDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAP 232
+P S PP + EP P + P L A S +L+S PTP P
Sbjct: 165 SPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPS-------IPTPP-DFIP 216
Query: 233 PAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPP 280
PAPPL + L PPPPP +PP P + L PP
Sbjct: 217 PAPPL-AFLAPPPPPVPA-----------PAPPAPASPHTVGTRLFPP 252
Score = 31.6 bits (70), Expect = 1.2
Identities = 25/78 (32%), Positives = 28/78 (35%), Gaps = 10/78 (12%)
Query: 232 PPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPP----DEELPLPL------DLPPPP 281
P PLP S PP P+ + E+ PPPP D E P P PP
Sbjct: 955 PQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPR 1014
Query: 282 PLDGDELGLPPPPPGFGP 299
D LP PG P
Sbjct: 1015 NNYSDLRQLPNAGPGAPP 1032
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
sapiens]
Length = 1188
Score = 62.0 bits (149), Expect = 8e-10
Identities = 43/105 (40%), Positives = 52/105 (49%), Gaps = 11/105 (10%)
Query: 217 AEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPP--PDEELPLP 274
+E GG+P P + P PP P L+PPPPP+ PP LE LSPP +P P
Sbjct: 155 SEPPGGSPLPSPPSTAPPPP-PLLLEPPPPPSMAP--PPPPVLEALSPPHTLSSPSIPTP 211
Query: 275 LD-LPPPPPLDGDELGLPPPPPGFGPDEPSWVPASYLEKVVTLYP 318
D +PP PPL PPPPP P P+ PAS L+P
Sbjct: 212 PDFIPPAPPL---AFLAPPPPPVPAPAPPA--PASPHTVGTRLFP 251
Score = 45.1 bits (105), Expect = 1e-04
Identities = 51/165 (30%), Positives = 62/165 (37%), Gaps = 39/165 (23%)
Query: 172 KAPATPASATLGRPPRIPEP--VHL----PVVPD--------GRLSAASSASSLA--SAG 215
+AP AT P R+P P H+ V PD G L A + AS S
Sbjct: 322 EAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQS 381
Query: 216 SAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPP------PDE 269
A+ G P P PPAPPLP PP PPAA + P ++ + PP P
Sbjct: 382 QADERAGTPPPAPPLPPPAPPLPPPA-PPLPPAAPPL----PCAQKAAHPPAGFTKTPKS 436
Query: 270 ELPLPLDLPPPPPLDGDELGLPPPPPGFGPDEP-SWVPASYLEKV 313
P L P P PP P P W S +EK+
Sbjct: 437 SSPA---LKPKPN--------PPSPENTASSAPVDWRDPSQMEKL 470
Score = 40.0 bits (92), Expect = 0.003
Identities = 39/120 (32%), Positives = 43/120 (35%), Gaps = 32/120 (26%)
Query: 199 DGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPP---------APPLPSSLDPPPPPAA 249
+G L SS L + + P P G A P PLPS PPP
Sbjct: 116 NGNLRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPP-- 173
Query: 250 VEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPL-----DGDELGLP--PPPPGFGPDEP 302
PP L L PPPP P PPPPP+ L P P PP F P P
Sbjct: 174 ------PPLL--LEPPPP------PSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAP 219
Score = 32.3 bits (72), Expect = 0.69
Identities = 34/108 (31%), Positives = 42/108 (38%), Gaps = 23/108 (21%)
Query: 176 TPASATLGRPPRIPEPVHLPVV---PDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAP 232
+P S PP + EP P + P L A S +L+S PTP P
Sbjct: 165 SPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPS-------IPTPP-DFIP 216
Query: 233 PAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPP 280
PAPPL + L PPPPP +PP P + L PP
Sbjct: 217 PAPPL-AFLAPPPPPVPA-----------PAPPAPASPHTVGTRLFPP 252
Score = 31.6 bits (70), Expect = 1.2
Identities = 25/78 (32%), Positives = 28/78 (35%), Gaps = 10/78 (12%)
Query: 232 PPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPP----DEELPLPL------DLPPPP 281
P PLP S PP P+ + E+ PPPP D E P P PP
Sbjct: 955 PQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPR 1014
Query: 282 PLDGDELGLPPPPPGFGP 299
D LP PG P
Sbjct: 1015 NNYSDLRQLPNAGPGAPP 1032
>gi|52485606 formin-like 2 [Homo sapiens]
Length = 1092
Score = 62.0 bits (149), Expect = 8e-10
Identities = 44/114 (38%), Positives = 47/114 (41%), Gaps = 12/114 (10%)
Query: 194 LPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVF 253
LPVV G LS S + S G G + G PP PPLP S D P E
Sbjct: 494 LPVVASGTLSMGSEVVAGNSVGPTMGAASS----GPLPPPPPPLPPSSDTP------ETV 543
Query: 254 QRPPTLEELSPPPPDEELPLPLDL-PPPPPLDGDELGLPPPPPGFGPDEPSWVP 306
Q P + PPPP P P PPPPPL G P PP P PS P
Sbjct: 544 QNGPVTPPMPPPPPPPPPPPPPPPPPPPPPLPGPAAETVPAPP-LAPPLPSAPP 596
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 61.6 bits (148), Expect = 1e-09
Identities = 44/132 (33%), Positives = 53/132 (40%), Gaps = 8/132 (6%)
Query: 172 KAPATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAA 231
K +TP L +P P LP +P S + L APTP+ Q
Sbjct: 1414 KDTSTPDGPPLAPAAAVPGPPPLPGLPSAN-SNGTPEPPLLEEKPPPTPPPAPTPQPQPP 1472
Query: 232 PPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLP 291
PP PP +L PPP A PP PPPP +P P PPPPP L P
Sbjct: 1473 PPPPPPQPALPSPPPLVAPTPSSPPPPP---LPPPPPPAMPSP---PPPPPPAAAPLAAP 1526
Query: 292 PPPPGF-GPDEP 302
P P P++P
Sbjct: 1527 PEEPAAPSPEDP 1538
Score = 55.5 bits (132), Expect = 8e-08
Identities = 39/108 (36%), Positives = 43/108 (39%), Gaps = 21/108 (19%)
Query: 211 LASAGSAEG---VGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPP 267
LA A + G + G P+ P P L P PPPA Q PP PPPP
Sbjct: 1424 LAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPP-----PPPP 1478
Query: 268 DEELPLPLDL-------PPPPPLDGDELGLPPPPPGFGPDEPSWVPAS 308
LP P L PPPPPL PPPPP P PA+
Sbjct: 1479 QPALPSPPPLVAPTPSSPPPPPLP------PPPPPAMPSPPPPPPPAA 1520
Score = 53.5 bits (127), Expect = 3e-07
Identities = 40/104 (38%), Positives = 46/104 (44%), Gaps = 9/104 (8%)
Query: 210 SLASAGSAEGVGGAPTPKGQAAPPAPPL-PSSLDPPPPP------AAVEVFQRPPTLEEL 262
S++SA SA PK + P PPL P++ P PPP A PP LEE
Sbjct: 1397 SISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEE- 1455
Query: 263 SPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPDEPSWVP 306
PPP P P PPPPP + LP PPP P S P
Sbjct: 1456 KPPPTPPPAPTPQPQPPPPP-PPPQPALPSPPPLVAPTPSSPPP 1498
Score = 47.0 bits (110), Expect = 3e-05
Identities = 36/102 (35%), Positives = 42/102 (41%), Gaps = 17/102 (16%)
Query: 172 KAPATPASATLGRP-PRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQA 230
K P TP A +P P P P P +P A + SS P P
Sbjct: 1456 KPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSS-------------PPPPPLP 1502
Query: 231 APPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELP 272
PP P +PS PPPPPAA + P E +P P D ELP
Sbjct: 1503 PPPPPAMPSP-PPPPPPAAAPL--AAPPEEPAAPSPEDPELP 1541
Score = 46.2 bits (108), Expect = 5e-05
Identities = 58/190 (30%), Positives = 71/190 (37%), Gaps = 26/190 (13%)
Query: 150 GHGIKDLSTQLSRTGTLSRKSIKAPATPASATLGRPPRI------PE-PVHLPVVPDGRL 202
G G K+L G +KS P A +T P + P+ P+ LP P L
Sbjct: 750 GAGAKEL-------GAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLL 802
Query: 203 -SAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEE 261
S S A S + + S GV P + P PP P PPP P +E R LE
Sbjct: 803 PSVLSHAPSPSPSASKVGVH-LLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEP 861
Query: 262 LSPPP---PDEELPLP-------LDLPPPPPLDGDELGLPPPPPGFGPDEPSWVPASYLE 311
+P P P+E L P L P PP GD PP G P P+
Sbjct: 862 AAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGT 921
Query: 312 KVVTLYPYTS 321
K P TS
Sbjct: 922 KAPRFVPLTS 931
Score = 41.2 bits (95), Expect = 0.001
Identities = 39/129 (30%), Positives = 51/129 (39%), Gaps = 8/129 (6%)
Query: 174 PATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPP 233
PA G P P P HLP L A+SSA++ A+ S+ + AAP
Sbjct: 221 PAQTPPYRPGPPDPPPPPRHLPT--QFNLLASSSAAAAAAEQSSPQLYNF----SGAAPG 274
Query: 234 APPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPP 293
PP +L P ++ +QRP + + PPPP L L P G L
Sbjct: 275 PPPPERAL--PRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACS 332
Query: 294 PPGFGPDEP 302
P G G P
Sbjct: 333 PLGGGEPSP 341
Score = 40.0 bits (92), Expect = 0.003
Identities = 46/163 (28%), Positives = 54/163 (33%), Gaps = 67/163 (41%)
Query: 177 PASATLGRPPRIP--------------EPVHLPVVPDGRLSAASSASSLASAG--SAEGV 220
P+S +L PP P +P P VP ++ LA G G+
Sbjct: 165 PSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVP-----SSLGFERLAGGGVLGPAGL 219
Query: 221 GGAPTPKGQAAPPAPPLPSSLDPPPPP---------------AAVEVFQRPPTLEELS-- 263
G A TP + PP DPPPPP AA Q P L S
Sbjct: 220 GPAQTPPYRPGPP--------DPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGA 271
Query: 264 ---PPPPDEELP----------LPLDLPPPPPLDGDELGLPPP 293
PPPP+ LP P PPPP PPP
Sbjct: 272 APGPPPPERALPRQDTVIKHYQRPASAQPPPP--------PPP 306
Score = 37.0 bits (84), Expect = 0.028
Identities = 28/83 (33%), Positives = 32/83 (38%), Gaps = 15/83 (18%)
Query: 190 EPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAA 249
+P H P VP R + A + SAG + AP PK A PP P P PP
Sbjct: 1665 KPWHRPPVPVRR---SGQAKNPVSAGGSS----APPPKAPAPPPKPETPEKTTSEKPP-- 1715
Query: 250 VEVFQRPPTLEELSPPPPDEELP 272
T E P PP E P
Sbjct: 1716 ------EQTPETAMPEPPAPEKP 1732
Score = 34.3 bits (77), Expect = 0.18
Identities = 35/120 (29%), Positives = 47/120 (39%), Gaps = 16/120 (13%)
Query: 221 GGAPTPKGQAAPPAP--PLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLP 278
GGA G+A PP + PPP P A + + P L L + P
Sbjct: 956 GGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKP 1015
Query: 279 P--PPPLDGDELGL---------PPPPPGFGPDEPSWVPASYLEKVVTLYPYTSQKDNEL 327
P P ++ + LGL PPPPP P P PAS + +T + S K +L
Sbjct: 1016 PELPSTVNAEPLGLIQSGPHQAAPPPPP---PPPPPPAPASEPKGGLTSPIFCSTKPKKL 1072
Score = 32.0 bits (71), Expect = 0.90
Identities = 18/38 (47%), Positives = 21/38 (55%), Gaps = 5/38 (13%)
Query: 211 LASAGSAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPA 248
L S +AE +G + QAAPP PP PPPPPA
Sbjct: 1018 LPSTVNAEPLGLIQSGPHQAAPPPPP-----PPPPPPA 1050
Score = 30.4 bits (67), Expect = 2.6
Identities = 24/79 (30%), Positives = 32/79 (40%), Gaps = 12/79 (15%)
Query: 215 GSAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLP 274
G A G G G P LPS+++ P + + Q P + +PPPP P
Sbjct: 996 GRASGAGPETPGLGLDPNKPPELPSTVNAEP----LGLIQSGP--HQAAPPPP------P 1043
Query: 275 LDLPPPPPLDGDELGLPPP 293
PPP P + GL P
Sbjct: 1044 PPPPPPAPASEPKGGLTSP 1062
Score = 29.3 bits (64), Expect = 5.8
Identities = 24/76 (31%), Positives = 27/76 (35%), Gaps = 20/76 (26%)
Query: 228 GQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDE 287
GQA P SS PP PA PPP E P PP E
Sbjct: 1678 GQAKNPVSAGGSSAPPPKAPA----------------PPPKPETP-EKTTSEKPPEQTPE 1720
Query: 288 LGLPPPPPGFGPDEPS 303
+P PP P++PS
Sbjct: 1721 TAMPEPP---APEKPS 1733
Score = 28.9 bits (63), Expect = 7.6
Identities = 16/59 (27%), Positives = 24/59 (40%)
Query: 224 PTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPP 282
P P ++ P+ + PPP A +P T E+ + P E+ P PP P
Sbjct: 1671 PVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAP 1729
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 60.8 bits (146), Expect = 2e-09
Identities = 53/158 (33%), Positives = 64/158 (40%), Gaps = 35/158 (22%)
Query: 172 KAPATPASATLGRPPRIPEPVHL-PVVPDGR--------LSAASSASSLASAGSAEGVGG 222
+AP P + G PP P P + P P R S A +A+ S V
Sbjct: 275 QAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAV 334
Query: 223 APTPKGQAAPPAPP-LPSSL---DPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLP 278
P P + PP PP LPSS PPPPP+ + V ++PPPP P
Sbjct: 335 PPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGV-------GPVAPPPP----------P 377
Query: 279 PPPPLDGDELGLPPPPPGFGPDEPSWVPASYLEKVVTL 316
PPPP G PPPPPG D VP + K L
Sbjct: 378 PPPPPPG-----PPPPPGLPSDGDHQVPTTAGNKAALL 410
Score = 55.8 bits (133), Expect = 6e-08
Identities = 34/95 (35%), Positives = 39/95 (41%), Gaps = 5/95 (5%)
Query: 218 EGVGGAPTPKGQA---APPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLP 274
E GG K + APP PP PPPPP PP PPP P
Sbjct: 260 EKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPS-RAP 318
Query: 275 LDLPPPPPLDGDELGLPPPPPG-FGPDEPSWVPAS 308
PPPPP + +PPPPP P P +P+S
Sbjct: 319 TAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSS 353
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 60.5 bits (145), Expect = 2e-09
Identities = 54/175 (30%), Positives = 73/175 (41%), Gaps = 17/175 (9%)
Query: 172 KAPATPASATLGRPPRIPEPVHLPVVPDGR-LSAASSASSLASAGS-----AEGVGGAPT 225
K PA PAS PP P PV P +P + A S L+ S A PT
Sbjct: 815 KQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPT 874
Query: 226 PKGQAAPPAPPLPSSLDPPPPPAA-VEVFQRPPTLEELSP--PPPDEELPLPLDLPPPPP 282
P + P P+P+++ P PPA + +P ++ SP PPP E L PPP P
Sbjct: 875 PPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSP 934
Query: 283 LDGDELGLPPPPPGFGP-DEPSWVPASYLEKVVT----LYPYTSQKDNELSFSEG 332
+ PPPPP P + S P K + P T Q+++ + S G
Sbjct: 935 VPAPP---PPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSG 986
Score = 50.4 bits (119), Expect = 2e-06
Identities = 47/157 (29%), Positives = 62/157 (39%), Gaps = 28/157 (17%)
Query: 173 APATPASATLGRPPRIPEPV--HLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQA 230
AP TP PP IP P+ P P + A +S ++A + + PTP
Sbjct: 759 APPTPPP-----PPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVT-QAAPPTPTPPVPP 812
Query: 231 APPAPPLPSSLDPPPPPAAVEVFQRPPTLEE----LSPPPPDEELPLPLDL--------P 278
A P P+S PP PP V PPTL + + PPP P+P + P
Sbjct: 813 AKKQPAFPASYIPPSPPTP-PVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPP 871
Query: 279 PPPPLDGDELGLPPPPPGFGPD-------EPSWVPAS 308
PP P + L P P P +P W P+S
Sbjct: 872 PPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSS 908
Score = 41.2 bits (95), Expect = 0.001
Identities = 35/124 (28%), Positives = 44/124 (35%), Gaps = 13/124 (10%)
Query: 158 TQLSRTGTLSRKSIKAPATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSA 217
T+L S K P P + P+I P P+G + + GSA
Sbjct: 671 TRLQNASQHSGALFKPPTPPVMQSQSVKPQILVP------PNGVVPPPPPPPPPPTPGSA 724
Query: 218 EGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDL 277
+ + AP AP LP PPPP +V PPPP PLP
Sbjct: 725 MA-------QLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQA 777
Query: 278 PPPP 281
PP P
Sbjct: 778 PPKP 781
Score = 39.7 bits (91), Expect = 0.004
Identities = 32/117 (27%), Positives = 43/117 (36%), Gaps = 7/117 (5%)
Query: 198 PDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSSLDP-PPPPAAVEVFQRP 256
P G + + S SS+ S G + K + P S + P P P V +
Sbjct: 563 PAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTAS 622
Query: 257 PTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPDEPSWVPASYLEKV 313
L PPPP P P PPPPPL P G P +V S + ++
Sbjct: 623 QPSPPLPPPPPPPPPPPPPPPPPPPPLPSQS------APSAGSAAPMFVKYSTITRL 673
Score = 38.1 bits (87), Expect = 0.013
Identities = 34/125 (27%), Positives = 46/125 (36%), Gaps = 10/125 (8%)
Query: 174 PATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPP 233
P P ++L PP P PV P P +S + S + +P G+ PP
Sbjct: 917 PPPPPESSLVFPPPPPSPVPAPPPPP---PPTASPTPDKSGSPGKKTSKTSSPGGKKPPP 973
Query: 234 APPLPSSLD-------PPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGD 286
P SS+ P P +V+ T S P E LP P P P L+
Sbjct: 974 TPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLS 1033
Query: 287 ELGLP 291
+ LP
Sbjct: 1034 GVNLP 1038
Score = 37.4 bits (85), Expect = 0.021
Identities = 27/95 (28%), Positives = 39/95 (41%), Gaps = 23/95 (24%)
Query: 207 SASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSSLD---------------PPPPPA--- 248
S SL S + G+P+ + P APP P L+ P
Sbjct: 996 SVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSG 1055
Query: 249 ----AVEVFQRPPTLEELSPPPPDEELPL-PLDLP 278
+V F PP+ + PPPP+ ELPL P+++P
Sbjct: 1056 RGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIP 1090
Score = 36.6 bits (83), Expect = 0.037
Identities = 38/135 (28%), Positives = 45/135 (33%), Gaps = 13/135 (9%)
Query: 165 TLSRKSIKAPATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAP 224
T S+ S P P PP P P LP SA S+A + + A
Sbjct: 620 TASQPSPPLPPPPPPPPPPPPPPPPPPPPLP--SQSAPSAGSAAPMFVKYSTITRLQNAS 677
Query: 225 TPKGQA-APPAPPLPSSLDPPP----PPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPP 279
G PP PP+ S P PP V PP PPPP + P
Sbjct: 678 QHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPP------PPPPTPGSAMAQLKPA 731
Query: 280 PPPLDGDELGLPPPP 294
P + PPPP
Sbjct: 732 PCAPSLPQFSAPPPP 746
Score = 36.2 bits (82), Expect = 0.048
Identities = 30/110 (27%), Positives = 39/110 (35%), Gaps = 39/110 (35%)
Query: 224 PTPKGQAAPPAPPLPSSLDPPPPP-----------AAVEVFQRPPTLEEL---------- 262
P+P PP PP P PPPPP +A +F + T+ L
Sbjct: 624 PSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGAL 683
Query: 263 ----SPP-------------PPDEELPLPLDLPPPPPLDGDELGLPPPPP 295
+PP PP+ +P P PPPPP G + P P
Sbjct: 684 FKPPTPPVMQSQSVKPQILVPPNGVVPPPPP-PPPPPTPGSAMAQLKPAP 732
Score = 29.3 bits (64), Expect = 5.8
Identities = 32/115 (27%), Positives = 47/115 (40%), Gaps = 14/115 (12%)
Query: 176 TPASATLGRPPRIPEP-------VHLP-VVPDGRLSAASSASSLASAGSAEGVGGAPTPK 227
+P+ TL P P+P V+LP V+ G +SA + + S + V P+P
Sbjct: 1012 SPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAP---VLSGRGKDSVVEFPSPP 1068
Query: 228 GQAAPPAPPLPSSLDPPPPPAAVEVF--QRPPTLEELSPPPPDEELPLPLDLPPP 280
+ P PP + L P PP VF P + ++P P PPP
Sbjct: 1069 SDSDFPPPPPETEL-PLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPP 1122
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 59.3 bits (142), Expect = 5e-09
Identities = 47/147 (31%), Positives = 61/147 (41%), Gaps = 14/147 (9%)
Query: 174 PATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAA-- 231
P+ P S PP+ P + LP + AS S + S + QA
Sbjct: 607 PSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 666
Query: 232 -PPAPPLPSSLDPP--PP--PAAVEVFQRPPTLE----ELSPPPPDEELPLPLDLPP--- 279
PP+PP+ + PP PP P+A Q PP+L ++ P PP P PP
Sbjct: 667 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 726
Query: 280 PPPLDGDELGLPPPPPGFGPDEPSWVP 306
PPPL L +PP PP P PS P
Sbjct: 727 PPPLAAPPLQVPPSPPASPPMSPSATP 753
Score = 50.1 bits (118), Expect = 3e-06
Identities = 56/197 (28%), Positives = 69/197 (35%), Gaps = 48/197 (24%)
Query: 118 LPPGQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATP 177
LPP Q +P PPL+P L+ S +AP
Sbjct: 627 LPPLQAPPSPPASPPLSP------------------------------LATPSPQAPNAL 656
Query: 178 ASATLGRP--PRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAP 235
A L P P PV P P S S S+ + + + P + P +P
Sbjct: 657 AVHLLQAPFSPPPSPPVQAPFSPPA--SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP 714
Query: 236 PLPSSLDPP---PPPAAVEVFQRPPTLEELSPP------PPDEELPL----PLDLPPPPP 282
P+ S PP PPP A Q PP+ SPP PP PL PL +PP PP
Sbjct: 715 PMSPSATPPPQAPPPLAAPPLQVPPS-PPASPPMSPSATPPPRVPPLLAAPPLQVPPSPP 773
Query: 283 LDGDELGLPPPPPGFGP 299
L PPP P
Sbjct: 774 ASLPMSPLAKPPPQAPP 790
Score = 49.3 bits (116), Expect = 5e-06
Identities = 55/202 (27%), Positives = 69/202 (34%), Gaps = 46/202 (22%)
Query: 119 PPGQKVIAP-ENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATP 177
PP P ENLP L P PL + + L+ ++ P P
Sbjct: 526 PPASLTTPPLENLPSLAP---PPLQ------------------TASAPLTTPHLETPPCP 564
Query: 178 ASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAP-TPKGQAAPPAPP 236
A L PP P P P + A ++ +G+ P +P P APP
Sbjct: 565 APCPLQAPPS-PLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPP 623
Query: 237 ---LPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEE-------LPLPLDLPPPPPLDGD 286
LP PP PPA+ P L L+ P P L P PP PP+
Sbjct: 624 XLALPPLQAPPSPPAS-------PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA- 675
Query: 287 ELGLPPPPPGFGPDEPSWVPAS 308
P PP P PS P S
Sbjct: 676 ----PFSPPASPPVSPSATPPS 693
Score = 48.1 bits (113), Expect = 1e-05
Identities = 52/196 (26%), Positives = 68/196 (34%), Gaps = 20/196 (10%)
Query: 119 PPGQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPA 178
PP Q ++P P +P PL + LS+ S + S+ P
Sbjct: 467 PPLQTSLSPAVSPLSSPLTIHPL------------QALSSLASHSPQAPLSSLIMPPLET 514
Query: 179 SATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLP 238
++L P P L P L + + L +A + TP A P P
Sbjct: 515 QSSLAPPSLQTPPASLTTPPLENLPSLAPPP-LQTASAPLTTPHLETPPCPAPCPLQAPP 573
Query: 239 SSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELP----LPLDLPP---PPPLDGDELGLP 291
S L PPP + PP PP + LP PL PP PP L L P
Sbjct: 574 SPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAP 633
Query: 292 PPPPGFGPDEPSWVPA 307
P PP P P P+
Sbjct: 634 PSPPASPPLSPLATPS 649
Score = 47.0 bits (110), Expect = 3e-05
Identities = 49/168 (29%), Positives = 66/168 (39%), Gaps = 30/168 (17%)
Query: 138 RRPLNFGCLD-DIGHGIKDLSTQLS---RTGTLSRKSIKAPATPASATLGRPPRIPEPVH 193
RRP G L + +T LS R+G +R + +APA P+ P+ + +
Sbjct: 226 RRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK----PKGLQALR 281
Query: 194 LPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVF 253
P V R AA + L+S+ A P+P G A P PP ++ P P
Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLA-----TPSPSGTKARPVPPPDNAATPLPAT------ 330
Query: 254 QRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPDE 301
L P PP L PL L PP P L P PP P +
Sbjct: 331 --------LPPSPP---LATPLPLAPPSPSAPPSLQTLPSPPATPPSQ 367
Score = 45.8 bits (107), Expect = 6e-05
Identities = 47/156 (30%), Positives = 56/156 (35%), Gaps = 33/156 (21%)
Query: 168 RKSIKAPA----TPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGA 223
RKS+ + + T S R P + P SA +S S SA G A
Sbjct: 206 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 265
Query: 224 PT--------------------PKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELS 263
P P+ AAP PL SS P P+ + RP
Sbjct: 266 PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKA--RPV------ 317
Query: 264 PPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGP 299
PPP + PLP LPP PPL L L PP P P
Sbjct: 318 PPPDNAATPLPATLPPSPPL-ATPLPLAPPSPSAPP 352
Score = 43.5 bits (101), Expect = 3e-04
Identities = 57/217 (26%), Positives = 77/217 (35%), Gaps = 58/217 (26%)
Query: 119 PPGQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPA 178
PP Q +P PP++P P +L+ ++ P +P
Sbjct: 671 PPVQAPFSPPASPPVSPSATPPSQ-------------------APPSLAAPPLQVPPSPP 711
Query: 179 -----SATLGRPPRIPEPVHLPV--VPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAA 231
S + PP+ P P+ P VP ++ + S + AP +
Sbjct: 712 ASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQ---V 768
Query: 232 PPAPP--LPSSLDPPPPPAAVEVFQRPPTLEELSPPP----------PDEELPL-PLDLP 278
PP+PP LP S PPP A PP L+ L PP P LP+ PL P
Sbjct: 769 PPSPPASLPMSPLAKPPPQAPPALATPP-LQALPSPPASFPGQAPFSPSASLPMSPLATP 827
Query: 279 PP---PPLDGDELGLPPPPP------------GFGPD 300
PP P L L +PP PP GPD
Sbjct: 828 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 864
Score = 42.7 bits (99), Expect = 5e-04
Identities = 48/186 (25%), Positives = 68/186 (36%), Gaps = 37/186 (19%)
Query: 167 SRKSIKAPATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLAS----------AGS 216
++ S+ +P+ PAS PP + P+ LP P + S + + S L+S +
Sbjct: 437 TQASLTSPSRPASTPPDSPP-LQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSL 495
Query: 217 AEGVGGAP----------TPKGQAAPPAPPLPSSLDPPP-------PPAAVEVFQRPPTL 259
A AP T A P P+SL PP P ++ P T
Sbjct: 496 ASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTT 555
Query: 260 EELSPPP-----PDEELPLPLDLPPPPPLDGDELGLPPP--PPGFGPDEPSWVPASYLEK 312
L PP P + P PL PPP + PPP PP +P+ L
Sbjct: 556 PHLETPPCPAPCPLQAPPSPLTTPPPE--TPSSIATPPPQAPPALASPPLQGLPSPPLSP 613
Query: 313 VVTLYP 318
+ T P
Sbjct: 614 LATPPP 619
Score = 41.2 bits (95), Expect = 0.001
Identities = 42/148 (28%), Positives = 49/148 (33%), Gaps = 30/148 (20%)
Query: 177 PASATLGRPPRIPE-----PVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAA 231
P S + PPR+P P+ +P P L + A A A TP QA
Sbjct: 746 PMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPA-----LATPPLQAL 800
Query: 232 PPAP-------PLPSSLDPPPPPAAVEVFQRPPTLEE-LSPPPPDEELPLPLDLPPPPPL 283
P P P S P P A Q PP L L PP L P PP
Sbjct: 801 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT 860
Query: 284 DGDELGL------------PPPPPGFGP 299
G + + PPPPP P
Sbjct: 861 PGPDTSVSGPRLTLALAPGPPPPPSRSP 888
Score = 38.5 bits (88), Expect = 0.010
Identities = 45/149 (30%), Positives = 51/149 (34%), Gaps = 43/149 (28%)
Query: 175 ATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAP---TPKGQAA 231
ATP ATL PP P LP+ P SA S +L S + P TP QA
Sbjct: 324 ATPLPATL--PPSPPLATPLPLAPPSP-SAPPSLQTLPSPPATPPSQAPPSMTTPPMQAP 380
Query: 232 PPAPPLPS----------SLDPPPPPAAVEVFQRP-----PTLEEL-------------- 262
P +P SL PP P A+ Q PTL+
Sbjct: 381 PSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQAS 440
Query: 263 --------SPPPPDEELPLPLDLPPPPPL 283
S PP L PL LP PPL
Sbjct: 441 LTSPSRPASTPPDSPPLQAPLSLPASPPL 469
Score = 33.9 bits (76), Expect = 0.24
Identities = 45/171 (26%), Positives = 57/171 (33%), Gaps = 8/171 (4%)
Query: 119 PPGQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPA 178
PP Q +P PP++P P L L S +L + P A
Sbjct: 733 PPLQVPPSPPASPPMSPSATPPPRVPPL----LAAPPLQVPPSPPASLPMSPLAKPPPQA 788
Query: 179 SATLGRPP--RIPEP-VHLPVVPDGRLSAASSASSLASAG-SAEGVGGAPTPKGQAAPPA 234
L PP +P P P SA+ S LA+ A V AP + +PPA
Sbjct: 789 PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA 848
Query: 235 PPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDG 285
P + PP P P L+P PP P P L G
Sbjct: 849 SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 899
Score = 32.7 bits (73), Expect = 0.53
Identities = 52/198 (26%), Positives = 63/198 (31%), Gaps = 61/198 (30%)
Query: 169 KSIKAPATPASATLG----RPPRIPEPVHLPVVPDGR--LSAASSASSLASAGSAEGVGG 222
K+ A TPA+ G RPP P P PV P L AA + A A G+GG
Sbjct: 9 KAGAAARTPAARAPGLLTPRPPGSPRPPP-PVTPAALRVLGAAGAVGRKPLAERAGGIGG 67
Query: 223 APTPKG--QAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEE-------LPL 273
A P+ +A P SS +P P A +R P + SP P P
Sbjct: 68 ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG 127
Query: 274 PL---------------------------------DLPPPPP------------LDGDEL 288
PL D P P G E+
Sbjct: 128 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 187
Query: 289 GLPPPPPGFGPDEPSWVP 306
GLP P P P P+ P
Sbjct: 188 GLPRPAPSARPRPPTEGP 205
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 59.3 bits (142), Expect = 5e-09
Identities = 44/111 (39%), Positives = 47/111 (42%), Gaps = 14/111 (12%)
Query: 206 SSASSLASAGSAEGVGGAPTPK-GQAAPPAPPLPS----SLDPPPPPAAVEVFQRPPTLE 260
SS S + A +G P PK G A PPAPP P + PPPPP PP
Sbjct: 292 SSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPS 351
Query: 261 ELS-PPPPDEELPLPLDLPP--------PPPLDGDELGLPPPPPGFGPDEP 302
S PP PD P P PP PPPL G PPPPP P P
Sbjct: 352 PPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGP 402
Score = 56.6 bits (135), Expect = 3e-08
Identities = 45/140 (32%), Positives = 54/140 (38%), Gaps = 14/140 (10%)
Query: 168 RKSIKAPATPASAT-LGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTP 226
R S+ +P+ P A LG PP P+P P P + G G TP
Sbjct: 291 RSSVVSPSHPPPAPPLGSPPG-PKPGFAP--PPAPPPPPPPMIGIPPPPPPVGFGSPGTP 347
Query: 227 KGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGD 286
+ P PP P PPPPP PP + + PPP P PPPPP
Sbjct: 348 PPPSPPSFPPHPDFAAPPPPPP-------PPAADYPTLPPPPLSQPTGGAPPPPPPPPPP 400
Query: 287 ELGLPPPPPGFGPDEPSWVP 306
PPPPP G D +P
Sbjct: 401 G---PPPPPFTGADGQPAIP 417
Score = 46.2 bits (108), Expect = 5e-05
Identities = 41/128 (32%), Positives = 49/128 (38%), Gaps = 38/128 (29%)
Query: 213 SAGSAEGVGGA---PTPKGQAAPPAPPLPSSLDPPPPPA--------------------- 248
S G E V + P P+ +A P S + PPPPA
Sbjct: 234 SIGCVENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSS 293
Query: 249 AVEVFQRPPTLEELSPPPPDEEL-PLPLDLPPPPPLDGDELGLPPPPP--GFG------- 298
V PP SPP P P P PPPPP+ +G+PPPPP GFG
Sbjct: 294 VVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPM----IGIPPPPPPVGFGSPGTPPP 349
Query: 299 PDEPSWVP 306
P PS+ P
Sbjct: 350 PSPPSFPP 357
Score = 35.8 bits (81), Expect = 0.062
Identities = 29/95 (30%), Positives = 37/95 (38%), Gaps = 13/95 (13%)
Query: 173 APATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAP 232
+P TP + PP P P A+ +L ++ GGAP P P
Sbjct: 343 SPGTPPPPS---PPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPP-----P 394
Query: 233 PAPPLPSSLDPPPPPAAVEVFQR--PPTLEELSPP 265
P PP P PPPPP Q PP L + + P
Sbjct: 395 PPPPPPG---PPPPPFTGADGQPAIPPPLSDTTKP 426
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 59.3 bits (142), Expect = 5e-09
Identities = 36/97 (37%), Positives = 42/97 (43%), Gaps = 10/97 (10%)
Query: 219 GVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPT---------LEELSPPPPDE 269
GV P P PP PPLP SL PPPPP + + PPT +L PP P
Sbjct: 229 GVKRPPPPLMNGLPPRPPLPESL-PPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGV 287
Query: 270 ELPLPLDLPPPPPLDGDELGLPPPPPGFGPDEPSWVP 306
P P+ PP + G+ PP PG P P P
Sbjct: 288 HPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHP 324
Score = 55.5 bits (132), Expect = 8e-08
Identities = 35/78 (44%), Positives = 38/78 (48%), Gaps = 9/78 (11%)
Query: 232 PPAPPL----PSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDE 287
PPAPP P + PPPP + RPP E L PPPP LPLP +PP P
Sbjct: 217 PPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPG-GLPLP-PMPPTGPAPSGP 274
Query: 288 LG---LPPPPPGFGPDEP 302
G LPPP PG P P
Sbjct: 275 PGPPQLPPPAPGVHPPAP 292
Score = 55.1 bits (131), Expect = 1e-07
Identities = 42/136 (30%), Positives = 47/136 (34%), Gaps = 20/136 (14%)
Query: 171 IKAPATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQA 230
+K P P G PPR P P LP P G G+ P P
Sbjct: 230 VKRPPPPLMN--GLPPRPPLPESLPPPPPG------------------GLPLPPMPPTGP 269
Query: 231 APPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGL 290
AP PP P L PP P P + PP P P P PP P + G+
Sbjct: 270 APSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGV 329
Query: 291 PPPPPGFGPDEPSWVP 306
PP PG P P P
Sbjct: 330 HPPAPGVHPPAPGVHP 345
Score = 39.7 bits (91), Expect = 0.004
Identities = 28/72 (38%), Positives = 36/72 (50%), Gaps = 12/72 (16%)
Query: 232 PPAP---PLPSSLDPPPP---PAAVEVFQRPPTLEELSPP--PPDEELPLPLDLPPPPPL 283
PPAP P + P PP P+A V +PP + +P PP P+P L PP P
Sbjct: 395 PPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPPT---PMPPMLRPPLPS 451
Query: 284 DGDELGLPPPPP 295
+G +PPPPP
Sbjct: 452 EGPG-NIPPPPP 462
Score = 37.7 bits (86), Expect = 0.016
Identities = 31/92 (33%), Positives = 37/92 (40%), Gaps = 10/92 (10%)
Query: 222 GAPTPKGQAAPPAP---PLPSS-LDPPPP---PAAVEVFQRPPTLEELSPPPPDEELPLP 274
G P PPAP P PS+ + P P PAA V + P + PP P P
Sbjct: 349 GVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVH---PPAPGMHPQAP 405
Query: 275 LDLPPPPPLDGDELGLPPPPPGFGPDEPSWVP 306
P PP + G+ P PPG P P P
Sbjct: 406 GVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHP 437
Score = 35.4 bits (80), Expect = 0.081
Identities = 43/167 (25%), Positives = 56/167 (33%), Gaps = 32/167 (19%)
Query: 174 PATPASATLGRPPRIPEP---VH--LPVV--PDGRLSAASSASSLASAGSAEGVGGAPTP 226
P PA + PP++P P VH PVV P + + + G G P
Sbjct: 266 PTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPP 325
Query: 227 KGQAAPPAP-----------------PLPSSLDPP-----PPPAAVEVFQRP---PTLEE 261
PPAP P + PP PPP+A Q P P
Sbjct: 326 TSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPA 385
Query: 262 LSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPDEPSWVPAS 308
+ P P P P P P + G+ P PG P P P++
Sbjct: 386 VHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSN 432
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 58.9 bits (141), Expect = 7e-09
Identities = 58/198 (29%), Positives = 70/198 (35%), Gaps = 37/198 (18%)
Query: 112 LATVQRLPPGQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSI 171
L VQ PP AP + PP P+ P G+ S+ +S G S +S+
Sbjct: 396 LPKVQIPPPAHP--APVHQPPPLPHRPPPPP---PSSYMTGMSTTSSYMSGEGYQSLQSM 450
Query: 172 KAPATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAA 231
P+ L PP P HLP P P
Sbjct: 451 MKTEGPSYGAL--PPAYGPPAHLPYHPH------------------------VYPPNPPP 484
Query: 232 PPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLP 291
PP PP P+S PP P + PP + PPP LP +PP PP LGLP
Sbjct: 485 PPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPP---PGLGLP 541
Query: 292 P---PPPGFGPDEPSWVP 306
P PPP P VP
Sbjct: 542 PASYPPPAVPPGGQPPVP 559
Score = 35.0 bits (79), Expect = 0.11
Identities = 34/125 (27%), Positives = 43/125 (34%), Gaps = 16/125 (12%)
Query: 174 PATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGA--PTPK---- 227
P+ P +P + +P P P + S+ E A P PK
Sbjct: 299 PSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKI 358
Query: 228 GQAAPPAPPLPSSLDPPPPPAAVEVFQRPP------TLEELSPPPPDEELPL----PLDL 277
PP PP D PP AA PP L ++ PPP P+ PL
Sbjct: 359 ETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPH 418
Query: 278 PPPPP 282
PPPP
Sbjct: 419 RPPPP 423
Score = 34.3 bits (77), Expect = 0.18
Identities = 45/170 (26%), Positives = 58/170 (34%), Gaps = 19/170 (11%)
Query: 146 LDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASATLGRPPRIPEPVHLPVVPDGRLSAA 205
L+DI H I DL +Q K TP L +PP + +P V + S +
Sbjct: 247 LEDICHQILDLYSQ--------GKQQMPHHTPHQ--LQQPPSLQPTPQVPQVQQSQPSQS 296
Query: 206 SSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPP 265
S S + P Q P P S P P P E +
Sbjct: 297 SEPSQPQQKDPQQ-------PAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAE 349
Query: 266 PPDEELP-LPLDLPPPPPLDGDELGLPPPPPGFGPDEPSW-VPASYLEKV 313
PP ++P + PP PP PP G EP V A+ L KV
Sbjct: 350 PPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKV 399
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 58.9 bits (141), Expect = 7e-09
Identities = 54/190 (28%), Positives = 75/190 (39%), Gaps = 26/190 (13%)
Query: 119 PPGQKVIAPENLPPLTPYCRRPLNFGCLDD-IGHGIKDL-STQLSR------TGTLSRKS 170
PP K +A + P P P+ L I K++ +T SR T TL K
Sbjct: 1478 PPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKK 1537
Query: 171 IKAPATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSA---EGVGGAPTPK 227
A P A + +P P P +P + + A+ +S AS+ A GAP+PK
Sbjct: 1538 TPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPK 1597
Query: 228 GQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDE--ELPLPLDLPPPPPLDG 285
PPA PS + P PPA ++PP P++ P P P PP+
Sbjct: 1598 ELLIPPAVTSPSPKEAPTPPA-------------VTPPSPEKGPATPAPKGTPTSPPVTP 1644
Query: 286 DELGLPPPPP 295
L P P
Sbjct: 1645 SSLKDSPTSP 1654
Score = 56.2 bits (134), Expect = 4e-08
Identities = 52/165 (31%), Positives = 65/165 (39%), Gaps = 33/165 (20%)
Query: 170 SIKAPATPASATLGRPPR---IPEPVHLPVVPDG----------RLSAASSASSLASAGS 216
S P +P TL PP+ P V+LP +G LS SS+ A A
Sbjct: 868 SAVTPLSPKGVTL--PPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATP 925
Query: 217 A-EGVGGAPTPKGQAAPPA---------PPLPSSLDPPPPPAAVEVFQRPPTLEELSPPP 266
A +G+ +P+PKG PPA P PS P PPAA PP+ + P
Sbjct: 926 APKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAAT-----PPSPKGGPATP 980
Query: 267 PDEELPLPLDLPPPPPLDGDELGLP---PPPPGFGPDEPSWVPAS 308
+ P P PP P G P P PP P P PA+
Sbjct: 981 SPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAA 1025
Score = 55.8 bits (133), Expect = 6e-08
Identities = 62/213 (29%), Positives = 75/213 (35%), Gaps = 29/213 (13%)
Query: 111 TLATVQRLPPGQKVIAPENLPPLTPYCRRPLNFGCL---DDIGHGIKDLSTQLSRTGTLS 167
T A P G P P TP P G L G +T S G L+
Sbjct: 1128 TPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA 1187
Query: 168 RKSIK-APATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASS----LASAGSAEGVGG 222
S K AP TPA+ P P G L+ S + A+ S +G
Sbjct: 1188 TPSPKGAPTTPAAT--------------PPSPKGGLATPSPKGAPTTPAATPPSPKGGLA 1233
Query: 223 APTPKGQAAPPA--PPLPSS--LDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLP 278
P+PKG PA PP P PPP A PP+L+ PP + P P +
Sbjct: 1234 TPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVT 1293
Query: 279 PPPPLDGDELGLP---PPPPGFGPDEPSWVPAS 308
PP P G P P PP P P P +
Sbjct: 1294 PPSPKGGPATSPPKGAPTPPAATPPSPKGSPGT 1326
Score = 50.4 bits (119), Expect = 2e-06
Identities = 54/194 (27%), Positives = 69/194 (35%), Gaps = 28/194 (14%)
Query: 119 PPGQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPA 178
PP +P+ P TP + G +T S G + S+K TP
Sbjct: 1035 PPAATPPSPKGSPAATPLPK-----------GAPTTPAATLPSPKGGPATPSLKGAPTPP 1083
Query: 179 SATLGRP---PRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAP 235
+AT P P P P P+ P AA+ S + G TP AA P
Sbjct: 1084 AATPPSPKGGPATPSPKGAPMPP-----AATPPSPKGGLATPPHKGAPTTP---AATPPS 1135
Query: 236 PLPSSLDPPPPPAAVEVFQRPPTLE-ELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPP 294
P PPP A PP+ + L+ PPP P PP P + GL P
Sbjct: 1136 PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP-----KGGLATPS 1190
Query: 295 PGFGPDEPSWVPAS 308
P P P+ P S
Sbjct: 1191 PKGAPTTPAATPPS 1204
Score = 49.7 bits (117), Expect = 4e-06
Identities = 48/161 (29%), Positives = 61/161 (37%), Gaps = 24/161 (14%)
Query: 174 PATPASATLGRPPRI--PEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAA 231
PATP+ PP P P P P + + A A+ S +G P+PKG
Sbjct: 954 PATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPA---ATPPSPKGGPATPSPKGAPT 1010
Query: 232 PPA--PPLPS---SLDPPPPPAAVEVFQRPPT---------LEELSPPPPDEELPLPLDL 277
PPA PP P + P P A+ PP+ L + +P P LP P
Sbjct: 1011 PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG 1070
Query: 278 PPPPPLDGDELGLPPPPPGFGPDEPSWVPASYLEKVVTLYP 318
P P L G P PP P P PA+ K + P
Sbjct: 1071 PATPSLKG-----APTPPAATPPSPKGGPATPSPKGAPMPP 1106
Score = 48.1 bits (113), Expect = 1e-05
Identities = 47/159 (29%), Positives = 60/159 (37%), Gaps = 26/159 (16%)
Query: 172 KAPATPASATLGRPPRI--PEPVHLPVVPDGRLSAASSASSLASAGSAEGVGG------- 222
KAPATPA P + P +P P R + ++L S + +
Sbjct: 1492 KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP 1551
Query: 223 ---APTPKGQAAPP----APPLPSSLDPPPPPAAVEVFQR--PPTLEELSPP----PPDE 269
P+PK A P AP PSS + PPA + P E L PP P +
Sbjct: 1552 AMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPK 1611
Query: 270 ELPLPLDLPPPPPLDGDELGLPPPPPGFGPDEPSWVPAS 308
E P P + PP P E G P P P P P+S
Sbjct: 1612 EAPTPPAVTPPSP----EKGPATPAPKGTPTSPPVTPSS 1646
Score = 46.6 bits (109), Expect = 4e-05
Identities = 50/155 (32%), Positives = 61/155 (39%), Gaps = 21/155 (13%)
Query: 157 STQLSRTGTLSRKSIK-APATPASATLGRP---PRIPEPVHLPVVPDGRLSAASSASSLA 212
+T S G L+ S K AP TPA AT P P P P P P A++ SL
Sbjct: 1223 ATPPSPKGGLATPSPKGAPTTPA-ATPPSPKGGPATPPPKGAPTPP------AATPPSLK 1275
Query: 213 SAGSAEGVGGAPTPKGQAAPPAPPLPSSLDPPP----PPAAVEVFQRPPTLEELSPPPPD 268
+ GAP P PP+P + PP PPAA PP+ + PP
Sbjct: 1276 GGLATPPHKGAPNP-AVVTPPSPKGGPATSPPKGAPTPPAAT-----PPSPKGSPGTPPP 1329
Query: 269 EELPLPLDLPPPPPLDGDELGLPPPPPGFGPDEPS 303
+ P P + PP P L P GP PS
Sbjct: 1330 KGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPS 1364
Score = 38.5 bits (88), Expect = 0.010
Identities = 42/138 (30%), Positives = 56/138 (40%), Gaps = 12/138 (8%)
Query: 155 DLSTQLSRTGTLSRKSIKAPATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASA 214
D S + G LS + AP P + + + H P P S AS+ +A
Sbjct: 1719 DPSAKNGSKGPLSTVA-PAPLLPVQKDSSKTAKGKDASHSPKGP--LAPPESKASTPLTA 1775
Query: 215 GSAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPT-----LEELSPP--PP 267
+ E V P +A P+PP+ L P P P Q P+ LE S P P
Sbjct: 1776 AAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPA 1835
Query: 268 DEELPLPLDLPPPPPLDG 285
DE+ LP L PP P+ G
Sbjct: 1836 DEDELLP--LIPPEPISG 1851
Score = 38.1 bits (87), Expect = 0.013
Identities = 48/173 (27%), Positives = 59/173 (34%), Gaps = 51/173 (29%)
Query: 172 KAPATPASAT-------LGRPPR--IPEP-VHLPVVPDGRLSAASSASS----LASAGSA 217
K TP +AT L PP P P V P P G + + + A+ S
Sbjct: 1261 KGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSP 1320
Query: 218 EGVGGAPTPKGQAAPPA----------------------PPLPSSLDPPPPPAAVEVFQR 255
+G G P PKG PPA P PSS + P PPAA +
Sbjct: 1321 KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKG 1380
Query: 256 PPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPDEPSWVPAS 308
P ++PP P P P GD P P P P PA+
Sbjct: 1381 GPA---MTPPSPKRG-------PAIPSPKGD-----PTSPAVIPLSPKKAPAT 1418
Score = 37.7 bits (86), Expect = 0.016
Identities = 44/148 (29%), Positives = 58/148 (39%), Gaps = 21/148 (14%)
Query: 163 TGTLSRKSIKAPATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLA----SAGSAE 218
T ++ + K P T S+ PP P+P G LS + A L S+ +A+
Sbjct: 1693 TPIITAPTRKGPQTKKSSATS-PPICPDP-SAKNGSKGPLSTVAPAPLLPVQKDSSKTAK 1750
Query: 219 GVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVE-VFQRPPTLEELSPPPPDEELPLPLDL 277
G + +PKG APP S P AA E V +P + + P P LPL
Sbjct: 1751 GKDASHSPKGPLAPPE----SKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLA--- 1803
Query: 278 PPPPPLDGDELGLPPPPPGFGPDEPSWV 305
P P P PP F P P V
Sbjct: 1804 PSPVPT-------LPPKQQFLPSSPGLV 1824
Score = 36.2 bits (82), Expect = 0.048
Identities = 31/91 (34%), Positives = 41/91 (45%), Gaps = 14/91 (15%)
Query: 172 KAPATPASATLGRPPRI--------PEPVHLPVVPDGRLSAASSASS--LASAGSAEGVG 221
+APATP+S PP + P P L + P + A + + S E
Sbjct: 1569 EAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGP 1628
Query: 222 GAPTPKGQAAPPAPPL-PSSL-DPPPPPAAV 250
P PKG P +PP+ PSSL D P PA+V
Sbjct: 1629 ATPAPKG--TPTSPPVTPSSLKDSPTSPASV 1657
Score = 35.8 bits (81), Expect = 0.062
Identities = 49/179 (27%), Positives = 61/179 (34%), Gaps = 44/179 (24%)
Query: 156 LSTQLSRTGTLSRKSIKAPATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAG 215
+S Q R T +K P TP +G PV +P+ LS S S A+
Sbjct: 801 VSPQTKRPPT--KKGSAGPDTP----IGNLSSPVSPVEASFLPENSLSFQGSKDSPATTH 854
Query: 216 SAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDE--ELPL 273
S PTP +P P PS++ P P + PT ++ P P E P
Sbjct: 855 S-------PTPP---SPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPA 904
Query: 274 PLDLP---------------PPP---PLDGDELGLP------PPPPGFGPDEPS--WVP 306
P P P P P G P PP P GP PS W P
Sbjct: 905 PKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP 963
Score = 33.9 bits (76), Expect = 0.24
Identities = 35/113 (30%), Positives = 46/113 (40%), Gaps = 16/113 (14%)
Query: 175 ATPASATLGRP-PRIPEPVHLPVVPDGRLSAASSASSLASAGSA----------EGVGGA 223
A +A LG+P P +P P P LSAA+ AS S + + G
Sbjct: 31 ALSVTAALGQPGPTLPPPCS-PAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGT 89
Query: 224 PTPKGQAAPPAPP-LPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPL 275
P G AP AP LP+ + PP PAA+ + P + P PL L
Sbjct: 90 ALPLG-TAPEAPTFLPNLIGPPISPAALAL--ASPMIAPTLKGTPSSSAPLAL 139
Score = 33.5 bits (75), Expect = 0.31
Identities = 47/178 (26%), Positives = 57/178 (32%), Gaps = 36/178 (20%)
Query: 157 STQLSRTGTLSRKSIKAPATPASATL---GRPPRIPEPVHLPVVPDGRLSAASSASSLAS 213
+T S+ G + S + P PA+ G P P P +P + S A S
Sbjct: 1352 TTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLS 1411
Query: 214 AGSAEGVG----GAPTP-KGQAAPPA------------------PPLPSSLDPPPPPAAV 250
A GA TP KG PPA P PSS P PA
Sbjct: 1412 PKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT 1471
Query: 251 EVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPDEPSWVPAS 308
PP+ +E P P P P G P P P P VPA+
Sbjct: 1472 -----PPSPKEPPAPKQVATSSSPKKAPATPAPMG-----APTLPAVIPSSPKEVPAT 1519
Score = 33.1 bits (74), Expect = 0.40
Identities = 53/215 (24%), Positives = 66/215 (30%), Gaps = 50/215 (23%)
Query: 172 KAPATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAA 231
KAPAT A P LP V + +A++ S + P P G
Sbjct: 1445 KAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPT 1504
Query: 232 PPA---------PPLPSS-LDPPPPPAAVEVFQRPPTL---EELSPP------------- 265
PA P PSS DP P A + + P TL E L PP
Sbjct: 1505 LPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAI 1564
Query: 266 ---------PPDEE--------------LPLPLDLPPPPPLDGDELGLPPPPPGFGPDEP 302
P +E P P +L PP + P PP P P
Sbjct: 1565 PTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSP 1624
Query: 303 SWVPASYLEK-VVTLYPYTSQKDNELSFSEGTVIC 336
PA+ K T P T + S +V C
Sbjct: 1625 EKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTC 1659
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 58.5 bits (140), Expect = 9e-09
Identities = 39/103 (37%), Positives = 43/103 (41%), Gaps = 24/103 (23%)
Query: 215 GSAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLP 274
G+ G P P G PP PP P+ PP PP PP PPPP + LP P
Sbjct: 209 GAVPGGDRFPGPAGPGGPP-PPFPAGQTPPRPPLGPPGPPGPP-----GPPPPGQVLPPP 262
Query: 275 L-------DLPPP-----------PPLDGDELGLPPPPPGFGP 299
L D PPP PPL G PPP PG+GP
Sbjct: 263 LAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGP 305
Score = 53.5 bits (127), Expect = 3e-07
Identities = 34/79 (43%), Positives = 34/79 (43%), Gaps = 7/79 (8%)
Query: 226 PKGQAAPPAPPLPSSLDPP-----PPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPP 280
P GQ PP PLP PP PPP Q PP PP P L PL L PP
Sbjct: 283 PFGQ--PPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPP 340
Query: 281 PPLDGDELGLPPPPPGFGP 299
P L G G PPP P P
Sbjct: 341 PHLPGPPPGAPPPAPHVNP 359
Score = 49.3 bits (116), Expect = 5e-06
Identities = 33/87 (37%), Positives = 37/87 (42%), Gaps = 11/87 (12%)
Query: 226 PKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPL-PLDLPPPPPLD 284
P G PP PP P + PPP RPP L P P + PL PL PPPP+
Sbjct: 243 PPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPP-PVLFPGQPFGQPPLGPLPPGPPPPVP 301
Query: 285 G---------DELGLPPPPPGFGPDEP 302
G + G PPPP F P P
Sbjct: 302 GYGPPPGPPPPQQGPPPPPGPFPPRPP 328
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 58.2 bits (139), Expect = 1e-08
Identities = 45/141 (31%), Positives = 60/141 (42%), Gaps = 24/141 (17%)
Query: 162 RTGTLSRKSIKAPATPASATLGRPPRIPEPVHLPVVPDGRLS--AASSASSLASAGSAEG 219
R L R+ ++ ++ P + P++ V+ D S +AS A S +G
Sbjct: 247 RQEQLEREQLEWERERRISSAAAPASVETPLN-SVLGDSSASEPGLQAASQPAETPSQQG 305
Query: 220 VGGAPTPKGQAAPPAPPLP-----SSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLP 274
+ P A PP PPLP +S+ PPPP PP L PPPP PLP
Sbjct: 306 IVLGPL----APPPPPPLPPGPAQASVALPPPPGPPP----PPPLPSTGPPPPPPPPPLP 357
Query: 275 LDLPPPPPLDGDELGLPPPPP 295
+PPPPP PPP P
Sbjct: 358 NQVPPPPP--------PPPAP 370
Score = 48.1 bits (113), Expect = 1e-05
Identities = 29/69 (42%), Positives = 31/69 (44%), Gaps = 18/69 (26%)
Query: 215 GSAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLP 274
G A+ P P G PP PPLPS+ PPPPP PP L PPPP
Sbjct: 322 GPAQASVALPPPPGP--PPPPPLPSTGPPPPPP--------PPPLPNQVPPPPPP----- 366
Query: 275 LDLPPPPPL 283
PP PPL
Sbjct: 367 ---PPAPPL 372
Score = 43.9 bits (102), Expect = 2e-04
Identities = 39/115 (33%), Positives = 45/115 (39%), Gaps = 26/115 (22%)
Query: 195 PVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQA---APPAPPLPSSLDPPPPPAAVE 251
P + L++ SS + G A TP Q P APP P L P P A+V
Sbjct: 270 PASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVA 329
Query: 252 VFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPDEPSWVP 306
L PPP PPPPPL G PPPPP P P+ VP
Sbjct: 330 ----------LPPPPGP---------PPPPPL--PSTGPPPPPP--PPPLPNQVP 361
Score = 33.1 bits (74), Expect = 0.40
Identities = 27/79 (34%), Positives = 38/79 (48%), Gaps = 11/79 (13%)
Query: 238 PSSLDPPPPPAAVEVFQRPPTLEELSPP---PPDEELPL-PLDLPPPPPL-DGD---ELG 289
P+S++ P + P L+ S P P + + L PL PPPPPL G +
Sbjct: 270 PASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVA 329
Query: 290 LPPPPPGFGPDEPSWVPAS 308
LPPPP GP P +P++
Sbjct: 330 LPPPP---GPPPPPPLPST 345
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 58.2 bits (139), Expect = 1e-08
Identities = 45/141 (31%), Positives = 60/141 (42%), Gaps = 24/141 (17%)
Query: 162 RTGTLSRKSIKAPATPASATLGRPPRIPEPVHLPVVPDGRLS--AASSASSLASAGSAEG 219
R L R+ ++ ++ P + P++ V+ D S +AS A S +G
Sbjct: 247 RQEQLEREQLEWERERRISSAAAPASVETPLN-SVLGDSSASEPGLQAASQPAETPSQQG 305
Query: 220 VGGAPTPKGQAAPPAPPLP-----SSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLP 274
+ P A PP PPLP +S+ PPPP PP L PPPP PLP
Sbjct: 306 IVLGPL----APPPPPPLPPGPAQASVALPPPPGPPP----PPPLPSTGPPPPPPPPPLP 357
Query: 275 LDLPPPPPLDGDELGLPPPPP 295
+PPPPP PPP P
Sbjct: 358 NQVPPPPP--------PPPAP 370
Score = 48.1 bits (113), Expect = 1e-05
Identities = 29/69 (42%), Positives = 31/69 (44%), Gaps = 18/69 (26%)
Query: 215 GSAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLP 274
G A+ P P G PP PPLPS+ PPPPP PP L PPPP
Sbjct: 322 GPAQASVALPPPPGP--PPPPPLPSTGPPPPPP--------PPPLPNQVPPPPPP----- 366
Query: 275 LDLPPPPPL 283
PP PPL
Sbjct: 367 ---PPAPPL 372
Score = 43.9 bits (102), Expect = 2e-04
Identities = 39/115 (33%), Positives = 45/115 (39%), Gaps = 26/115 (22%)
Query: 195 PVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQA---APPAPPLPSSLDPPPPPAAVE 251
P + L++ SS + G A TP Q P APP P L P P A+V
Sbjct: 270 PASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVA 329
Query: 252 VFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPDEPSWVP 306
L PPP PPPPPL G PPPPP P P+ VP
Sbjct: 330 ----------LPPPPGP---------PPPPPL--PSTGPPPPPP--PPPLPNQVP 361
Score = 33.1 bits (74), Expect = 0.40
Identities = 27/79 (34%), Positives = 38/79 (48%), Gaps = 11/79 (13%)
Query: 238 PSSLDPPPPPAAVEVFQRPPTLEELSPP---PPDEELPL-PLDLPPPPPL-DGD---ELG 289
P+S++ P + P L+ S P P + + L PL PPPPPL G +
Sbjct: 270 PASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVA 329
Query: 290 LPPPPPGFGPDEPSWVPAS 308
LPPPP GP P +P++
Sbjct: 330 LPPPP---GPPPPPPLPST 345
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.134 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,099,339
Number of Sequences: 37866
Number of extensions: 1512254
Number of successful extensions: 28364
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 753
Number of HSP's successfully gapped in prelim test: 1548
Number of HSP's that attempted gapping in prelim test: 9465
Number of HSP's gapped (non-prelim): 10185
length of query: 366
length of database: 18,247,518
effective HSP length: 104
effective length of query: 262
effective length of database: 14,309,454
effective search space: 3749076948
effective search space used: 3749076948
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.