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Search of human proteins with 14141157
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14141157 heterogeneous nuclear ribonucleoprotein H3 isoform
a [Homo sapiens]
(346 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14141157 heterogeneous nuclear ribonucleoprotein H3 isoform a... 743 0.0
gi|14141159 heterogeneous nuclear ribonucleoprotein H3 isoform b... 699 0.0
gi|5031753 heterogeneous nuclear ribonucleoprotein H1 [Homo sapi... 414 e-116
gi|74099697 heterogeneous nuclear ribonucleoprotein H2 [Homo sap... 413 e-115
gi|9624998 heterogeneous nuclear ribonucleoprotein H2 [Homo sapi... 413 e-115
gi|148470406 heterogeneous nuclear ribonucleoprotein F [Homo sap... 353 1e-97
gi|148470404 heterogeneous nuclear ribonucleoprotein F [Homo sap... 353 1e-97
gi|148470402 heterogeneous nuclear ribonucleoprotein F [Homo sap... 353 1e-97
gi|148470400 heterogeneous nuclear ribonucleoprotein F [Homo sap... 353 1e-97
gi|148470397 heterogeneous nuclear ribonucleoprotein F [Homo sap... 353 1e-97
gi|4826760 heterogeneous nuclear ribonucleoprotein F [Homo sapiens] 353 1e-97
gi|149193321 G-rich RNA sequence binding factor 1 isoform 1 [Hom... 115 4e-26
gi|149193319 G-rich RNA sequence binding factor 1 isoform 2 [Hom... 115 4e-26
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 83 4e-16
gi|170763533 RNA binding motif protein 35A isoform 5 [Homo sapiens] 76 4e-14
gi|170763529 RNA binding motif protein 35A isoform 3 [Homo sapiens] 76 4e-14
gi|170763527 RNA binding motif protein 35A isoform 4 [Homo sapiens] 76 4e-14
gi|170763525 RNA binding motif protein 35A isoform 2 [Homo sapiens] 76 4e-14
gi|56790297 RNA binding motif protein 35A isoform 1 [Homo sapiens] 76 4e-14
gi|45935393 RNA binding motif protein 35B [Homo sapiens] 74 3e-13
gi|118722349 RNA binding motif protein 12B [Homo sapiens] 74 3e-13
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 71 2e-12
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 71 2e-12
gi|55956899 keratin 9 [Homo sapiens] 63 3e-10
gi|109255251 loricrin [Homo sapiens] 62 6e-10
gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho... 62 8e-10
gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom... 62 8e-10
gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapi... 62 1e-09
gi|119395750 keratin 1 [Homo sapiens] 60 3e-09
gi|109452587 family with sequence similarity 98, member B isofor... 60 3e-09
>gi|14141157 heterogeneous nuclear ribonucleoprotein H3 isoform a
[Homo sapiens]
Length = 346
Score = 743 bits (1917), Expect = 0.0
Identities = 346/346 (100%), Positives = 346/346 (100%)
Query: 1 MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEA 60
MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEA
Sbjct: 1 MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEA 60
Query: 61 FVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGG 120
FVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGG
Sbjct: 61 FVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGG 120
Query: 121 RGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHG 180
RGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHG
Sbjct: 121 RGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHG 180
Query: 181 YGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVE 240
YGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVE
Sbjct: 181 YGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVE 240
Query: 241 FVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVG 300
FVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVG
Sbjct: 241 FVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVG 300
Query: 301 RMGMGNNYSGGYGTPDGLGGYGRGGGGSGGYYGQGGMSGGGWRGMY 346
RMGMGNNYSGGYGTPDGLGGYGRGGGGSGGYYGQGGMSGGGWRGMY
Sbjct: 301 RMGMGNNYSGGYGTPDGLGGYGRGGGGSGGYYGQGGMSGGGWRGMY 346
>gi|14141159 heterogeneous nuclear ribonucleoprotein H3 isoform b
[Homo sapiens]
Length = 331
Score = 699 bits (1804), Expect = 0.0
Identities = 331/346 (95%), Positives = 331/346 (95%), Gaps = 15/346 (4%)
Query: 1 MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEA 60
MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEA
Sbjct: 1 MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEA 60
Query: 61 FVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGG 120
FVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGG
Sbjct: 61 FVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGG 120
Query: 121 RGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHG 180
RGGYYGAGRGS YGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHG
Sbjct: 121 RGGYYGAGRGS---------------YGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHG 165
Query: 181 YGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVE 240
YGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVE
Sbjct: 166 YGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVE 225
Query: 241 FVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVG 300
FVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVG
Sbjct: 226 FVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVG 285
Query: 301 RMGMGNNYSGGYGTPDGLGGYGRGGGGSGGYYGQGGMSGGGWRGMY 346
RMGMGNNYSGGYGTPDGLGGYGRGGGGSGGYYGQGGMSGGGWRGMY
Sbjct: 286 RMGMGNNYSGGYGTPDGLGGYGRGGGGSGGYYGQGGMSGGGWRGMY 331
>gi|5031753 heterogeneous nuclear ribonucleoprotein H1 [Homo
sapiens]
Length = 449
Score = 414 bits (1063), Expect = e-116
Identities = 217/345 (62%), Positives = 243/345 (70%), Gaps = 28/345 (8%)
Query: 1 MDWVMKHNGPND---ASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRST 57
MDWV+KH GPN A+DG VRLRGLPFGCSKEEIVQFF GLEIVPNGITL +D+QGRST
Sbjct: 93 MDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRST 152
Query: 58 GEAFVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLG-QRPGPYDR 116
GEAFVQFAS+EIAE AL KHKERIGHRYIEIF+SSR+E++ YDPPR+L+ QRPGPYDR
Sbjct: 153 GEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDR 212
Query: 117 PIGGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNN-YGYGNDGFD-DRMRDGR 174
P GR GY GRG+ ++RMRRG Y GGYGG+DDY GYN+ YG+G+D F D
Sbjct: 213 PGAGR-GYNSIGRGAGFERMRRG--AYGGGYGGYDDYNGYNDGYGFGSDRFGRDLNYCFS 269
Query: 175 GMGGHGYGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRAT 234
GM H YG G GH VHMRGLP+RATENDI NFFSPLNP+RVHI+IG DGR T
Sbjct: 270 GMSDHRYGDGGSTFQS-TTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVT 328
Query: 235 GEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSG-------------MGGSG 281
GEADVEF THEDAVAAMSKDK NMQHRY+ELFLNST G G G+
Sbjct: 329 GEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGAS 388
Query: 282 MGGYGRD-----GMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGY 321
G YG G+ NQ YG + Y GGYG + GY
Sbjct: 389 GGAYGSQMMGGMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGY 433
Score = 72.8 bits (177), Expect = 4e-13
Identities = 54/155 (34%), Positives = 71/155 (45%), Gaps = 24/155 (15%)
Query: 196 FVHMRGLPFRATENDIANFFSPLN--PIRVHIDIGADGRATGEADVEFVTHEDAVAAMSK 253
FV +RGLPF ++ +I FFS L P + + + GR+TGEA V+F + E A A+ K
Sbjct: 112 FVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKK 171
Query: 254 DKNNMQHRYIELFLNSTPGGGSG-------MGGSGMGGYGRDGMDNQGGYGSVGR-MGMG 305
K + HRYIE+F +S + M G Y R G GY S+GR G
Sbjct: 172 HKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGR--GYNSIGRGAGFE 229
Query: 306 NNYSGGYGTPDGLGGYGRGGGGSGGYYGQGGMSGG 340
G YG GG GGY G + G
Sbjct: 230 RMRRGAYG------------GGYGGYDDYNGYNDG 252
Score = 68.6 bits (166), Expect = 8e-12
Identities = 33/81 (40%), Positives = 53/81 (65%), Gaps = 2/81 (2%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIV--PNGITLTMDYQGRSTGEAFVQFASKEIAENALG 75
V++RGLP+ CS +E+ +FF +I GI +GR +GEAFV+ S++ + AL
Sbjct: 13 VKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALK 72
Query: 76 KHKERIGHRYIEIFRSSRSEI 96
K +E +GHRY+E+F+S+ E+
Sbjct: 73 KDRETMGHRYVEVFKSNNVEM 93
Score = 68.2 bits (165), Expect = 1e-11
Identities = 51/148 (34%), Positives = 71/148 (47%), Gaps = 12/148 (8%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
V +RGLP+ ++ +I FF L V I + D GR TGEA V+FA+ E A A+ K
Sbjct: 291 VHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPD--GRVTGEADVEFATHEDAVAAMSKD 348
Query: 78 KERIGHRYIEIFRSSRSEIKGFYDPPRRL-------LGQRPGPY-DRPIGGRGGYYGAGR 129
K + HRY+E+F +S + G R + G G Y + +GG G +
Sbjct: 349 KANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGASGGAYGSQMMGGMGLSNQSSY 408
Query: 130 GSMYDRMRRGGDGYDGGYGGFDDYGGYN 157
G + GG Y GGYGG GY+
Sbjct: 409 GGPASQQLSGG--YGGGYGGQSSMSGYD 434
Score = 48.9 bits (115), Expect = 7e-06
Identities = 25/77 (32%), Positives = 41/77 (53%), Gaps = 4/77 (5%)
Query: 194 GHFVHMRGLPFRATENDIANFFSPLNPIR----VHIDIGADGRATGEADVEFVTHEDAVA 249
G V +RGLP+ + +++ FFS + +GR +GEA VE + ++
Sbjct: 10 GFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKL 69
Query: 250 AMSKDKNNMQHRYIELF 266
A+ KD+ M HRY+E+F
Sbjct: 70 ALKKDRETMGHRYVEVF 86
>gi|74099697 heterogeneous nuclear ribonucleoprotein H2 [Homo
sapiens]
Length = 449
Score = 413 bits (1061), Expect = e-115
Identities = 218/347 (62%), Positives = 246/347 (70%), Gaps = 32/347 (9%)
Query: 1 MDWVMKHNGPND---ASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRST 57
MDWV+KH GPN A+DG VRLRGLPFGCSKEEIVQFF GLEIVPNG+TL +D+QGRST
Sbjct: 93 MDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRST 152
Query: 58 GEAFVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLG-QRPGPYDR 116
GEAFVQFAS+EIAE AL KHKERIGHRYIEIF+SSR+E++ YDPPR+L+ QRPGPYDR
Sbjct: 153 GEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDR 212
Query: 117 PIGGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNN-YGYGNDGFD-DRMRDGR 174
P GR GY GRG+ ++RMRRG Y GGYGG+DDYGGYN+ YG+G+D F D
Sbjct: 213 PGAGR-GYNSIGRGAGFERMRRG--AYGGGYGGYDDYGGYNDGYGFGSDRFGRDLNYCFS 269
Query: 175 GMGGHGYGGAGDASSGFHG--GHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGR 232
GM H Y GD S F GH VHMRGLP+RATENDI NFFSPLNP+RVHI+IG DGR
Sbjct: 270 GMSDHRY---GDGGSSFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGR 326
Query: 233 ATGEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSG-------------MGG 279
TGEADVEF THEDAVAAM+KDK NMQHRY+ELFLNST G G G
Sbjct: 327 VTGEADVEFATHEDAVAAMAKDKANMQHRYVELFLNSTAGTSGGAYDHSYVELFLNSTAG 386
Query: 280 SGMGGYGRD-----GMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGY 321
+ G YG G+ NQ YG + Y GGYG + GY
Sbjct: 387 ASGGAYGSQMMGGMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGY 433
Score = 74.3 bits (181), Expect = 1e-13
Identities = 55/155 (35%), Positives = 72/155 (46%), Gaps = 24/155 (15%)
Query: 196 FVHMRGLPFRATENDIANFFSPLN--PIRVHIDIGADGRATGEADVEFVTHEDAVAAMSK 253
FV +RGLPF ++ +I FFS L P + + + GR+TGEA V+F + E A A+ K
Sbjct: 112 FVRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKK 171
Query: 254 DKNNMQHRYIELFLNSTPGGGSG-------MGGSGMGGYGRDGMDNQGGYGSVGR-MGMG 305
K + HRYIE+F +S + M G Y R G GY S+GR G
Sbjct: 172 HKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGR--GYNSIGRGAGFE 229
Query: 306 NNYSGGYGTPDGLGGYGRGGGGSGGYYGQGGMSGG 340
G YG GG GGY GG + G
Sbjct: 230 RMRRGAYG------------GGYGGYDDYGGYNDG 252
Score = 70.9 bits (172), Expect = 2e-12
Identities = 34/81 (41%), Positives = 55/81 (67%), Gaps = 2/81 (2%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIV--PNGITLTMDYQGRSTGEAFVQFASKEIAENALG 75
V++RGLP+ CS +E+++FF +I +GI +GR +GEAFV+ S+E + AL
Sbjct: 13 VKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKLALK 72
Query: 76 KHKERIGHRYIEIFRSSRSEI 96
K +E +GHRY+E+F+S+ E+
Sbjct: 73 KDRETMGHRYVEVFKSNSVEM 93
Score = 70.1 bits (170), Expect = 3e-12
Identities = 51/159 (32%), Positives = 72/159 (45%), Gaps = 34/159 (21%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
V +RGLP+ ++ +I FF L P + + + GR TGEA V+FA+ E A A+ K
Sbjct: 291 VHMRGLPYRATENDIYNFFSPLN--PMRVHIEIGPDGRVTGEADVEFATHEDAVAAMAKD 348
Query: 78 KERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPI---------GGRGGYYGA- 127
K + HRY+E+F +S + G G YD G GG YG+
Sbjct: 349 KANMQHRYVELFLNSTAGTSG-------------GAYDHSYVELFLNSTAGASGGAYGSQ 395
Query: 128 --GRGSMYDRMRRGGD-------GYDGGYGGFDDYGGYN 157
G + ++ GG GY GGYGG GY+
Sbjct: 396 MMGGMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGYD 434
Score = 50.8 bits (120), Expect = 2e-06
Identities = 26/81 (32%), Positives = 44/81 (54%), Gaps = 4/81 (4%)
Query: 194 GHFVHMRGLPFRATENDIANFFSPLN----PIRVHIDIGADGRATGEADVEFVTHEDAVA 249
G V +RGLP+ + +++ FFS + +GR +GEA VE + E+
Sbjct: 10 GFVVKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKL 69
Query: 250 AMSKDKNNMQHRYIELFLNST 270
A+ KD+ M HRY+E+F +++
Sbjct: 70 ALKKDRETMGHRYVEVFKSNS 90
>gi|9624998 heterogeneous nuclear ribonucleoprotein H2 [Homo
sapiens]
Length = 449
Score = 413 bits (1061), Expect = e-115
Identities = 218/347 (62%), Positives = 246/347 (70%), Gaps = 32/347 (9%)
Query: 1 MDWVMKHNGPND---ASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRST 57
MDWV+KH GPN A+DG VRLRGLPFGCSKEEIVQFF GLEIVPNG+TL +D+QGRST
Sbjct: 93 MDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRST 152
Query: 58 GEAFVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLG-QRPGPYDR 116
GEAFVQFAS+EIAE AL KHKERIGHRYIEIF+SSR+E++ YDPPR+L+ QRPGPYDR
Sbjct: 153 GEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDR 212
Query: 117 PIGGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNN-YGYGNDGFD-DRMRDGR 174
P GR GY GRG+ ++RMRRG Y GGYGG+DDYGGYN+ YG+G+D F D
Sbjct: 213 PGAGR-GYNSIGRGAGFERMRRG--AYGGGYGGYDDYGGYNDGYGFGSDRFGRDLNYCFS 269
Query: 175 GMGGHGYGGAGDASSGFHG--GHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGR 232
GM H Y GD S F GH VHMRGLP+RATENDI NFFSPLNP+RVHI+IG DGR
Sbjct: 270 GMSDHRY---GDGGSSFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGR 326
Query: 233 ATGEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSG-------------MGG 279
TGEADVEF THEDAVAAM+KDK NMQHRY+ELFLNST G G G
Sbjct: 327 VTGEADVEFATHEDAVAAMAKDKANMQHRYVELFLNSTAGTSGGAYDHSYVELFLNSTAG 386
Query: 280 SGMGGYGRD-----GMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGY 321
+ G YG G+ NQ YG + Y GGYG + GY
Sbjct: 387 ASGGAYGSQMMGGMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGY 433
Score = 74.3 bits (181), Expect = 1e-13
Identities = 55/155 (35%), Positives = 72/155 (46%), Gaps = 24/155 (15%)
Query: 196 FVHMRGLPFRATENDIANFFSPLN--PIRVHIDIGADGRATGEADVEFVTHEDAVAAMSK 253
FV +RGLPF ++ +I FFS L P + + + GR+TGEA V+F + E A A+ K
Sbjct: 112 FVRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKK 171
Query: 254 DKNNMQHRYIELFLNSTPGGGSG-------MGGSGMGGYGRDGMDNQGGYGSVGR-MGMG 305
K + HRYIE+F +S + M G Y R G GY S+GR G
Sbjct: 172 HKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGR--GYNSIGRGAGFE 229
Query: 306 NNYSGGYGTPDGLGGYGRGGGGSGGYYGQGGMSGG 340
G YG GG GGY GG + G
Sbjct: 230 RMRRGAYG------------GGYGGYDDYGGYNDG 252
Score = 70.9 bits (172), Expect = 2e-12
Identities = 34/81 (41%), Positives = 55/81 (67%), Gaps = 2/81 (2%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIV--PNGITLTMDYQGRSTGEAFVQFASKEIAENALG 75
V++RGLP+ CS +E+++FF +I +GI +GR +GEAFV+ S+E + AL
Sbjct: 13 VKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKLALK 72
Query: 76 KHKERIGHRYIEIFRSSRSEI 96
K +E +GHRY+E+F+S+ E+
Sbjct: 73 KDRETMGHRYVEVFKSNSVEM 93
Score = 70.1 bits (170), Expect = 3e-12
Identities = 51/159 (32%), Positives = 72/159 (45%), Gaps = 34/159 (21%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
V +RGLP+ ++ +I FF L P + + + GR TGEA V+FA+ E A A+ K
Sbjct: 291 VHMRGLPYRATENDIYNFFSPLN--PMRVHIEIGPDGRVTGEADVEFATHEDAVAAMAKD 348
Query: 78 KERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPI---------GGRGGYYGA- 127
K + HRY+E+F +S + G G YD G GG YG+
Sbjct: 349 KANMQHRYVELFLNSTAGTSG-------------GAYDHSYVELFLNSTAGASGGAYGSQ 395
Query: 128 --GRGSMYDRMRRGGD-------GYDGGYGGFDDYGGYN 157
G + ++ GG GY GGYGG GY+
Sbjct: 396 MMGGMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGYD 434
Score = 50.8 bits (120), Expect = 2e-06
Identities = 26/81 (32%), Positives = 44/81 (54%), Gaps = 4/81 (4%)
Query: 194 GHFVHMRGLPFRATENDIANFFSPLN----PIRVHIDIGADGRATGEADVEFVTHEDAVA 249
G V +RGLP+ + +++ FFS + +GR +GEA VE + E+
Sbjct: 10 GFVVKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKL 69
Query: 250 AMSKDKNNMQHRYIELFLNST 270
A+ KD+ M HRY+E+F +++
Sbjct: 70 ALKKDRETMGHRYVEVFKSNS 90
>gi|148470406 heterogeneous nuclear ribonucleoprotein F [Homo
sapiens]
Length = 415
Score = 353 bits (907), Expect = 1e-97
Identities = 190/328 (57%), Positives = 230/328 (70%), Gaps = 13/328 (3%)
Query: 1 MDWVMKHNGPNDA---SDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRST 57
MDWV+KH+GPN A +DG VRLRGLPFGC+KEEIVQFF GLEIVPNGITL +D +G+ T
Sbjct: 93 MDWVLKHSGPNSADSANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKIT 152
Query: 58 GEAFVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLG-QRPGPYDR 116
GEAFVQFAS+E+AE ALGKHKERIGHRYIE+F+SS+ E++ + DPP + + QRPGPYDR
Sbjct: 153 GEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDR 212
Query: 117 PIGGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNN-YGYGNDGFD-DRMRDGR 174
P G Y G + + +RMR G Y GYGG+++Y G ++ YG+ D F D
Sbjct: 213 P-GTARRYIGIVKQAGLERMRPG--AYSTGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLS 269
Query: 175 GMGGHGYGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRAT 234
GM H YG + + + GH VHMRGLP++ATENDI NFFSPLNP+RVHI+IG DGR T
Sbjct: 270 GMYDHRYGDS-EFTVQSTTGHCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVT 328
Query: 235 GEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSG-MGGYGRDGMDNQ 293
GEADVEF THE+AVAAMSKD+ NMQHRYIELFLNST G +G S M G G Q
Sbjct: 329 GEADVEFATHEEAVAAMSKDRANMQHRYIELFLNSTTGASNGAYSSQVMQGMGVSAA--Q 386
Query: 294 GGYGSVGRMGMGNNYSGGYGTPDGLGGY 321
Y + + Y GY + +GGY
Sbjct: 387 ATYSGLESQSVSGCYGAGYSGQNSMGGY 414
Score = 71.6 bits (174), Expect = 1e-12
Identities = 36/90 (40%), Positives = 53/90 (58%), Gaps = 2/90 (2%)
Query: 9 GPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPN--GITLTMDYQGRSTGEAFVQFAS 66
GP V+LRGLP+ CS E++ F I G+ +GR +GEAFV+ S
Sbjct: 4 GPEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGS 63
Query: 67 KEIAENALGKHKERIGHRYIEIFRSSRSEI 96
++ + AL K +E +GHRYIE+F+S R+E+
Sbjct: 64 EDDVKMALKKDRESMGHRYIEVFKSHRTEM 93
Score = 58.2 bits (139), Expect = 1e-08
Identities = 44/140 (31%), Positives = 62/140 (44%), Gaps = 15/140 (10%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
V +RGLP+ ++ +I FF L V I + D GR TGEA V+FA+ E A A+ K
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPD--GRVTGEADVEFATHEEAVAAMSKD 348
Query: 78 KERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGRGSMYDRMR 137
+ + HRYIE+F +S + G G Y + G A +
Sbjct: 349 RANMQHRYIELFLNSTT-------------GASNGAYSSQVMQGMGVSAAQATYSGLESQ 395
Query: 138 RGGDGYDGGYGGFDDYGGYN 157
Y GY G + GGY+
Sbjct: 396 SVSGCYGAGYSGQNSMGGYD 415
Score = 56.2 bits (134), Expect = 4e-08
Identities = 30/77 (38%), Positives = 42/77 (54%), Gaps = 4/77 (5%)
Query: 194 GHFVHMRGLPFRATENDIANFFSPLN----PIRVHIDIGADGRATGEADVEFVTHEDAVA 249
G V +RGLP+ + D+ NF S VH +GR +GEA VE + +D
Sbjct: 10 GFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKM 69
Query: 250 AMSKDKNNMQHRYIELF 266
A+ KD+ +M HRYIE+F
Sbjct: 70 ALKKDRESMGHRYIEVF 86
>gi|148470404 heterogeneous nuclear ribonucleoprotein F [Homo
sapiens]
Length = 415
Score = 353 bits (907), Expect = 1e-97
Identities = 190/328 (57%), Positives = 230/328 (70%), Gaps = 13/328 (3%)
Query: 1 MDWVMKHNGPNDA---SDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRST 57
MDWV+KH+GPN A +DG VRLRGLPFGC+KEEIVQFF GLEIVPNGITL +D +G+ T
Sbjct: 93 MDWVLKHSGPNSADSANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKIT 152
Query: 58 GEAFVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLG-QRPGPYDR 116
GEAFVQFAS+E+AE ALGKHKERIGHRYIE+F+SS+ E++ + DPP + + QRPGPYDR
Sbjct: 153 GEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDR 212
Query: 117 PIGGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNN-YGYGNDGFD-DRMRDGR 174
P G Y G + + +RMR G Y GYGG+++Y G ++ YG+ D F D
Sbjct: 213 P-GTARRYIGIVKQAGLERMRPG--AYSTGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLS 269
Query: 175 GMGGHGYGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRAT 234
GM H YG + + + GH VHMRGLP++ATENDI NFFSPLNP+RVHI+IG DGR T
Sbjct: 270 GMYDHRYGDS-EFTVQSTTGHCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVT 328
Query: 235 GEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSG-MGGYGRDGMDNQ 293
GEADVEF THE+AVAAMSKD+ NMQHRYIELFLNST G +G S M G G Q
Sbjct: 329 GEADVEFATHEEAVAAMSKDRANMQHRYIELFLNSTTGASNGAYSSQVMQGMGVSAA--Q 386
Query: 294 GGYGSVGRMGMGNNYSGGYGTPDGLGGY 321
Y + + Y GY + +GGY
Sbjct: 387 ATYSGLESQSVSGCYGAGYSGQNSMGGY 414
Score = 71.6 bits (174), Expect = 1e-12
Identities = 36/90 (40%), Positives = 53/90 (58%), Gaps = 2/90 (2%)
Query: 9 GPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPN--GITLTMDYQGRSTGEAFVQFAS 66
GP V+LRGLP+ CS E++ F I G+ +GR +GEAFV+ S
Sbjct: 4 GPEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGS 63
Query: 67 KEIAENALGKHKERIGHRYIEIFRSSRSEI 96
++ + AL K +E +GHRYIE+F+S R+E+
Sbjct: 64 EDDVKMALKKDRESMGHRYIEVFKSHRTEM 93
Score = 58.2 bits (139), Expect = 1e-08
Identities = 44/140 (31%), Positives = 62/140 (44%), Gaps = 15/140 (10%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
V +RGLP+ ++ +I FF L V I + D GR TGEA V+FA+ E A A+ K
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPD--GRVTGEADVEFATHEEAVAAMSKD 348
Query: 78 KERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGRGSMYDRMR 137
+ + HRYIE+F +S + G G Y + G A +
Sbjct: 349 RANMQHRYIELFLNSTT-------------GASNGAYSSQVMQGMGVSAAQATYSGLESQ 395
Query: 138 RGGDGYDGGYGGFDDYGGYN 157
Y GY G + GGY+
Sbjct: 396 SVSGCYGAGYSGQNSMGGYD 415
Score = 56.2 bits (134), Expect = 4e-08
Identities = 30/77 (38%), Positives = 42/77 (54%), Gaps = 4/77 (5%)
Query: 194 GHFVHMRGLPFRATENDIANFFSPLN----PIRVHIDIGADGRATGEADVEFVTHEDAVA 249
G V +RGLP+ + D+ NF S VH +GR +GEA VE + +D
Sbjct: 10 GFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKM 69
Query: 250 AMSKDKNNMQHRYIELF 266
A+ KD+ +M HRYIE+F
Sbjct: 70 ALKKDRESMGHRYIEVF 86
>gi|148470402 heterogeneous nuclear ribonucleoprotein F [Homo
sapiens]
Length = 415
Score = 353 bits (907), Expect = 1e-97
Identities = 190/328 (57%), Positives = 230/328 (70%), Gaps = 13/328 (3%)
Query: 1 MDWVMKHNGPNDA---SDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRST 57
MDWV+KH+GPN A +DG VRLRGLPFGC+KEEIVQFF GLEIVPNGITL +D +G+ T
Sbjct: 93 MDWVLKHSGPNSADSANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKIT 152
Query: 58 GEAFVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLG-QRPGPYDR 116
GEAFVQFAS+E+AE ALGKHKERIGHRYIE+F+SS+ E++ + DPP + + QRPGPYDR
Sbjct: 153 GEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDR 212
Query: 117 PIGGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNN-YGYGNDGFD-DRMRDGR 174
P G Y G + + +RMR G Y GYGG+++Y G ++ YG+ D F D
Sbjct: 213 P-GTARRYIGIVKQAGLERMRPG--AYSTGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLS 269
Query: 175 GMGGHGYGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRAT 234
GM H YG + + + GH VHMRGLP++ATENDI NFFSPLNP+RVHI+IG DGR T
Sbjct: 270 GMYDHRYGDS-EFTVQSTTGHCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVT 328
Query: 235 GEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSG-MGGYGRDGMDNQ 293
GEADVEF THE+AVAAMSKD+ NMQHRYIELFLNST G +G S M G G Q
Sbjct: 329 GEADVEFATHEEAVAAMSKDRANMQHRYIELFLNSTTGASNGAYSSQVMQGMGVSAA--Q 386
Query: 294 GGYGSVGRMGMGNNYSGGYGTPDGLGGY 321
Y + + Y GY + +GGY
Sbjct: 387 ATYSGLESQSVSGCYGAGYSGQNSMGGY 414
Score = 71.6 bits (174), Expect = 1e-12
Identities = 36/90 (40%), Positives = 53/90 (58%), Gaps = 2/90 (2%)
Query: 9 GPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPN--GITLTMDYQGRSTGEAFVQFAS 66
GP V+LRGLP+ CS E++ F I G+ +GR +GEAFV+ S
Sbjct: 4 GPEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGS 63
Query: 67 KEIAENALGKHKERIGHRYIEIFRSSRSEI 96
++ + AL K +E +GHRYIE+F+S R+E+
Sbjct: 64 EDDVKMALKKDRESMGHRYIEVFKSHRTEM 93
Score = 58.2 bits (139), Expect = 1e-08
Identities = 44/140 (31%), Positives = 62/140 (44%), Gaps = 15/140 (10%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
V +RGLP+ ++ +I FF L V I + D GR TGEA V+FA+ E A A+ K
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPD--GRVTGEADVEFATHEEAVAAMSKD 348
Query: 78 KERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGRGSMYDRMR 137
+ + HRYIE+F +S + G G Y + G A +
Sbjct: 349 RANMQHRYIELFLNSTT-------------GASNGAYSSQVMQGMGVSAAQATYSGLESQ 395
Query: 138 RGGDGYDGGYGGFDDYGGYN 157
Y GY G + GGY+
Sbjct: 396 SVSGCYGAGYSGQNSMGGYD 415
Score = 56.2 bits (134), Expect = 4e-08
Identities = 30/77 (38%), Positives = 42/77 (54%), Gaps = 4/77 (5%)
Query: 194 GHFVHMRGLPFRATENDIANFFSPLN----PIRVHIDIGADGRATGEADVEFVTHEDAVA 249
G V +RGLP+ + D+ NF S VH +GR +GEA VE + +D
Sbjct: 10 GFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKM 69
Query: 250 AMSKDKNNMQHRYIELF 266
A+ KD+ +M HRYIE+F
Sbjct: 70 ALKKDRESMGHRYIEVF 86
>gi|148470400 heterogeneous nuclear ribonucleoprotein F [Homo
sapiens]
Length = 415
Score = 353 bits (907), Expect = 1e-97
Identities = 190/328 (57%), Positives = 230/328 (70%), Gaps = 13/328 (3%)
Query: 1 MDWVMKHNGPNDA---SDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRST 57
MDWV+KH+GPN A +DG VRLRGLPFGC+KEEIVQFF GLEIVPNGITL +D +G+ T
Sbjct: 93 MDWVLKHSGPNSADSANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKIT 152
Query: 58 GEAFVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLG-QRPGPYDR 116
GEAFVQFAS+E+AE ALGKHKERIGHRYIE+F+SS+ E++ + DPP + + QRPGPYDR
Sbjct: 153 GEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDR 212
Query: 117 PIGGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNN-YGYGNDGFD-DRMRDGR 174
P G Y G + + +RMR G Y GYGG+++Y G ++ YG+ D F D
Sbjct: 213 P-GTARRYIGIVKQAGLERMRPG--AYSTGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLS 269
Query: 175 GMGGHGYGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRAT 234
GM H YG + + + GH VHMRGLP++ATENDI NFFSPLNP+RVHI+IG DGR T
Sbjct: 270 GMYDHRYGDS-EFTVQSTTGHCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVT 328
Query: 235 GEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSG-MGGYGRDGMDNQ 293
GEADVEF THE+AVAAMSKD+ NMQHRYIELFLNST G +G S M G G Q
Sbjct: 329 GEADVEFATHEEAVAAMSKDRANMQHRYIELFLNSTTGASNGAYSSQVMQGMGVSAA--Q 386
Query: 294 GGYGSVGRMGMGNNYSGGYGTPDGLGGY 321
Y + + Y GY + +GGY
Sbjct: 387 ATYSGLESQSVSGCYGAGYSGQNSMGGY 414
Score = 71.6 bits (174), Expect = 1e-12
Identities = 36/90 (40%), Positives = 53/90 (58%), Gaps = 2/90 (2%)
Query: 9 GPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPN--GITLTMDYQGRSTGEAFVQFAS 66
GP V+LRGLP+ CS E++ F I G+ +GR +GEAFV+ S
Sbjct: 4 GPEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGS 63
Query: 67 KEIAENALGKHKERIGHRYIEIFRSSRSEI 96
++ + AL K +E +GHRYIE+F+S R+E+
Sbjct: 64 EDDVKMALKKDRESMGHRYIEVFKSHRTEM 93
Score = 58.2 bits (139), Expect = 1e-08
Identities = 44/140 (31%), Positives = 62/140 (44%), Gaps = 15/140 (10%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
V +RGLP+ ++ +I FF L V I + D GR TGEA V+FA+ E A A+ K
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPD--GRVTGEADVEFATHEEAVAAMSKD 348
Query: 78 KERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGRGSMYDRMR 137
+ + HRYIE+F +S + G G Y + G A +
Sbjct: 349 RANMQHRYIELFLNSTT-------------GASNGAYSSQVMQGMGVSAAQATYSGLESQ 395
Query: 138 RGGDGYDGGYGGFDDYGGYN 157
Y GY G + GGY+
Sbjct: 396 SVSGCYGAGYSGQNSMGGYD 415
Score = 56.2 bits (134), Expect = 4e-08
Identities = 30/77 (38%), Positives = 42/77 (54%), Gaps = 4/77 (5%)
Query: 194 GHFVHMRGLPFRATENDIANFFSPLN----PIRVHIDIGADGRATGEADVEFVTHEDAVA 249
G V +RGLP+ + D+ NF S VH +GR +GEA VE + +D
Sbjct: 10 GFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKM 69
Query: 250 AMSKDKNNMQHRYIELF 266
A+ KD+ +M HRYIE+F
Sbjct: 70 ALKKDRESMGHRYIEVF 86
>gi|148470397 heterogeneous nuclear ribonucleoprotein F [Homo
sapiens]
Length = 415
Score = 353 bits (907), Expect = 1e-97
Identities = 190/328 (57%), Positives = 230/328 (70%), Gaps = 13/328 (3%)
Query: 1 MDWVMKHNGPNDA---SDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRST 57
MDWV+KH+GPN A +DG VRLRGLPFGC+KEEIVQFF GLEIVPNGITL +D +G+ T
Sbjct: 93 MDWVLKHSGPNSADSANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKIT 152
Query: 58 GEAFVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLG-QRPGPYDR 116
GEAFVQFAS+E+AE ALGKHKERIGHRYIE+F+SS+ E++ + DPP + + QRPGPYDR
Sbjct: 153 GEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDR 212
Query: 117 PIGGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNN-YGYGNDGFD-DRMRDGR 174
P G Y G + + +RMR G Y GYGG+++Y G ++ YG+ D F D
Sbjct: 213 P-GTARRYIGIVKQAGLERMRPG--AYSTGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLS 269
Query: 175 GMGGHGYGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRAT 234
GM H YG + + + GH VHMRGLP++ATENDI NFFSPLNP+RVHI+IG DGR T
Sbjct: 270 GMYDHRYGDS-EFTVQSTTGHCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVT 328
Query: 235 GEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSG-MGGYGRDGMDNQ 293
GEADVEF THE+AVAAMSKD+ NMQHRYIELFLNST G +G S M G G Q
Sbjct: 329 GEADVEFATHEEAVAAMSKDRANMQHRYIELFLNSTTGASNGAYSSQVMQGMGVSAA--Q 386
Query: 294 GGYGSVGRMGMGNNYSGGYGTPDGLGGY 321
Y + + Y GY + +GGY
Sbjct: 387 ATYSGLESQSVSGCYGAGYSGQNSMGGY 414
Score = 71.6 bits (174), Expect = 1e-12
Identities = 36/90 (40%), Positives = 53/90 (58%), Gaps = 2/90 (2%)
Query: 9 GPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPN--GITLTMDYQGRSTGEAFVQFAS 66
GP V+LRGLP+ CS E++ F I G+ +GR +GEAFV+ S
Sbjct: 4 GPEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGS 63
Query: 67 KEIAENALGKHKERIGHRYIEIFRSSRSEI 96
++ + AL K +E +GHRYIE+F+S R+E+
Sbjct: 64 EDDVKMALKKDRESMGHRYIEVFKSHRTEM 93
Score = 58.2 bits (139), Expect = 1e-08
Identities = 44/140 (31%), Positives = 62/140 (44%), Gaps = 15/140 (10%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
V +RGLP+ ++ +I FF L V I + D GR TGEA V+FA+ E A A+ K
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPD--GRVTGEADVEFATHEEAVAAMSKD 348
Query: 78 KERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGRGSMYDRMR 137
+ + HRYIE+F +S + G G Y + G A +
Sbjct: 349 RANMQHRYIELFLNSTT-------------GASNGAYSSQVMQGMGVSAAQATYSGLESQ 395
Query: 138 RGGDGYDGGYGGFDDYGGYN 157
Y GY G + GGY+
Sbjct: 396 SVSGCYGAGYSGQNSMGGYD 415
Score = 56.2 bits (134), Expect = 4e-08
Identities = 30/77 (38%), Positives = 42/77 (54%), Gaps = 4/77 (5%)
Query: 194 GHFVHMRGLPFRATENDIANFFSPLN----PIRVHIDIGADGRATGEADVEFVTHEDAVA 249
G V +RGLP+ + D+ NF S VH +GR +GEA VE + +D
Sbjct: 10 GFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKM 69
Query: 250 AMSKDKNNMQHRYIELF 266
A+ KD+ +M HRYIE+F
Sbjct: 70 ALKKDRESMGHRYIEVF 86
>gi|4826760 heterogeneous nuclear ribonucleoprotein F [Homo sapiens]
Length = 415
Score = 353 bits (907), Expect = 1e-97
Identities = 190/328 (57%), Positives = 230/328 (70%), Gaps = 13/328 (3%)
Query: 1 MDWVMKHNGPNDA---SDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRST 57
MDWV+KH+GPN A +DG VRLRGLPFGC+KEEIVQFF GLEIVPNGITL +D +G+ T
Sbjct: 93 MDWVLKHSGPNSADSANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKIT 152
Query: 58 GEAFVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLG-QRPGPYDR 116
GEAFVQFAS+E+AE ALGKHKERIGHRYIE+F+SS+ E++ + DPP + + QRPGPYDR
Sbjct: 153 GEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDR 212
Query: 117 PIGGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNN-YGYGNDGFD-DRMRDGR 174
P G Y G + + +RMR G Y GYGG+++Y G ++ YG+ D F D
Sbjct: 213 P-GTARRYIGIVKQAGLERMRPG--AYSTGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLS 269
Query: 175 GMGGHGYGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRAT 234
GM H YG + + + GH VHMRGLP++ATENDI NFFSPLNP+RVHI+IG DGR T
Sbjct: 270 GMYDHRYGDS-EFTVQSTTGHCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVT 328
Query: 235 GEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSG-MGGYGRDGMDNQ 293
GEADVEF THE+AVAAMSKD+ NMQHRYIELFLNST G +G S M G G Q
Sbjct: 329 GEADVEFATHEEAVAAMSKDRANMQHRYIELFLNSTTGASNGAYSSQVMQGMGVSAA--Q 386
Query: 294 GGYGSVGRMGMGNNYSGGYGTPDGLGGY 321
Y + + Y GY + +GGY
Sbjct: 387 ATYSGLESQSVSGCYGAGYSGQNSMGGY 414
Score = 71.6 bits (174), Expect = 1e-12
Identities = 36/90 (40%), Positives = 53/90 (58%), Gaps = 2/90 (2%)
Query: 9 GPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPN--GITLTMDYQGRSTGEAFVQFAS 66
GP V+LRGLP+ CS E++ F I G+ +GR +GEAFV+ S
Sbjct: 4 GPEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGS 63
Query: 67 KEIAENALGKHKERIGHRYIEIFRSSRSEI 96
++ + AL K +E +GHRYIE+F+S R+E+
Sbjct: 64 EDDVKMALKKDRESMGHRYIEVFKSHRTEM 93
Score = 58.2 bits (139), Expect = 1e-08
Identities = 44/140 (31%), Positives = 62/140 (44%), Gaps = 15/140 (10%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
V +RGLP+ ++ +I FF L V I + D GR TGEA V+FA+ E A A+ K
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPD--GRVTGEADVEFATHEEAVAAMSKD 348
Query: 78 KERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGRGSMYDRMR 137
+ + HRYIE+F +S + G G Y + G A +
Sbjct: 349 RANMQHRYIELFLNSTT-------------GASNGAYSSQVMQGMGVSAAQATYSGLESQ 395
Query: 138 RGGDGYDGGYGGFDDYGGYN 157
Y GY G + GGY+
Sbjct: 396 SVSGCYGAGYSGQNSMGGYD 415
Score = 56.2 bits (134), Expect = 4e-08
Identities = 30/77 (38%), Positives = 42/77 (54%), Gaps = 4/77 (5%)
Query: 194 GHFVHMRGLPFRATENDIANFFSPLN----PIRVHIDIGADGRATGEADVEFVTHEDAVA 249
G V +RGLP+ + D+ NF S VH +GR +GEA VE + +D
Sbjct: 10 GFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKM 69
Query: 250 AMSKDKNNMQHRYIELF 266
A+ KD+ +M HRYIE+F
Sbjct: 70 ALKKDRESMGHRYIEVF 86
>gi|149193321 G-rich RNA sequence binding factor 1 isoform 1 [Homo
sapiens]
Length = 480
Score = 115 bits (289), Expect = 4e-26
Identities = 52/79 (65%), Positives = 64/79 (81%)
Query: 195 HFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKD 254
HFVHMRGLPF+A DI NFF+PL P+R+ ++ + G+ATGEADV F THEDAVAAM KD
Sbjct: 401 HFVHMRGLPFQANAQDIINFFAPLKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKD 460
Query: 255 KNNMQHRYIELFLNSTPGG 273
++++ HRYIELFLNS P G
Sbjct: 461 RSHVHHRYIELFLNSCPKG 479
Score = 98.6 bits (244), Expect = 7e-21
Identities = 50/85 (58%), Positives = 64/85 (75%), Gaps = 3/85 (3%)
Query: 14 SDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGR-STGEAFVQFASKEIAEN 72
+DG VRLRGLP+ C++++IV FF GL IV IT MDY+GR TGEA+VQF E+A
Sbjct: 248 NDGVVRLRGLPYSCNEKDIVDFFAGLNIVD--ITFVMDYRGRRKTGEAYVQFEEPEMANQ 305
Query: 73 ALGKHKERIGHRYIEIFRSSRSEIK 97
AL KH+E IG+RYIEIF S R+E++
Sbjct: 306 ALLKHREEIGNRYIEIFPSRRNEVR 330
Score = 58.2 bits (139), Expect = 1e-08
Identities = 24/81 (29%), Positives = 48/81 (59%), Gaps = 2/81 (2%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIV--PNGITLTMDYQGRSTGEAFVQFASKEIAENALG 75
+R +GLP+ C+ E+++ FF I NGI ++ G+ G+A ++ S++ + AL
Sbjct: 152 IRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALE 211
Query: 76 KHKERIGHRYIEIFRSSRSEI 96
KH+ +G RY+E++ + ++
Sbjct: 212 KHRMYMGQRYVEVYEINNEDV 232
Score = 58.2 bits (139), Expect = 1e-08
Identities = 31/75 (41%), Positives = 46/75 (61%), Gaps = 2/75 (2%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
V +RGLPF + ++I+ FF L+ P IT+ G++TGEA V F + E A A+ K
Sbjct: 403 VHMRGLPFQANAQDIINFFAPLK--PVRITMEYSSSGKATGEADVHFETHEDAVAAMLKD 460
Query: 78 KERIGHRYIEIFRSS 92
+ + HRYIE+F +S
Sbjct: 461 RSHVHHRYIELFLNS 475
Score = 51.6 bits (122), Expect = 1e-06
Identities = 29/71 (40%), Positives = 42/71 (59%), Gaps = 1/71 (1%)
Query: 197 VHMRGLPFRATENDIANFFSPLNPIRVHIDIGADG-RATGEADVEFVTHEDAVAAMSKDK 255
V +RGLP+ E DI +FF+ LN + + + G R TGEA V+F E A A+ K +
Sbjct: 252 VRLRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGRRKTGEAYVQFEEPEMANQALLKHR 311
Query: 256 NNMQHRYIELF 266
+ +RYIE+F
Sbjct: 312 EEIGNRYIEIF 322
Score = 45.8 bits (107), Expect = 6e-05
Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 6/75 (8%)
Query: 197 VHMRGLPFRATENDIANFFSPLNPIR-----VHIDIGADGRATGEADVEFVTHEDAVAAM 251
+ +GLP+ T D+ NFFS IR +H + DG+ G+A +E + +D A+
Sbjct: 152 IRAQGLPWSCTMEDVLNFFSDCR-IRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKAL 210
Query: 252 SKDKNNMQHRYIELF 266
K + M RY+E++
Sbjct: 211 EKHRMYMGQRYVEVY 225
>gi|149193319 G-rich RNA sequence binding factor 1 isoform 2 [Homo
sapiens]
Length = 318
Score = 115 bits (289), Expect = 4e-26
Identities = 52/79 (65%), Positives = 64/79 (81%)
Query: 195 HFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKD 254
HFVHMRGLPF+A DI NFF+PL P+R+ ++ + G+ATGEADV F THEDAVAAM KD
Sbjct: 239 HFVHMRGLPFQANAQDIINFFAPLKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKD 298
Query: 255 KNNMQHRYIELFLNSTPGG 273
++++ HRYIELFLNS P G
Sbjct: 299 RSHVHHRYIELFLNSCPKG 317
Score = 98.6 bits (244), Expect = 7e-21
Identities = 50/85 (58%), Positives = 64/85 (75%), Gaps = 3/85 (3%)
Query: 14 SDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGR-STGEAFVQFASKEIAEN 72
+DG VRLRGLP+ C++++IV FF GL IV IT MDY+GR TGEA+VQF E+A
Sbjct: 86 NDGVVRLRGLPYSCNEKDIVDFFAGLNIVD--ITFVMDYRGRRKTGEAYVQFEEPEMANQ 143
Query: 73 ALGKHKERIGHRYIEIFRSSRSEIK 97
AL KH+E IG+RYIEIF S R+E++
Sbjct: 144 ALLKHREEIGNRYIEIFPSRRNEVR 168
Score = 58.2 bits (139), Expect = 1e-08
Identities = 31/75 (41%), Positives = 46/75 (61%), Gaps = 2/75 (2%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
V +RGLPF + ++I+ FF L+ P IT+ G++TGEA V F + E A A+ K
Sbjct: 241 VHMRGLPFQANAQDIINFFAPLK--PVRITMEYSSSGKATGEADVHFETHEDAVAAMLKD 298
Query: 78 KERIGHRYIEIFRSS 92
+ + HRYIE+F +S
Sbjct: 299 RSHVHHRYIELFLNS 313
Score = 51.6 bits (122), Expect = 1e-06
Identities = 29/71 (40%), Positives = 42/71 (59%), Gaps = 1/71 (1%)
Query: 197 VHMRGLPFRATENDIANFFSPLNPIRVHIDIGADG-RATGEADVEFVTHEDAVAAMSKDK 255
V +RGLP+ E DI +FF+ LN + + + G R TGEA V+F E A A+ K +
Sbjct: 90 VRLRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGRRKTGEAYVQFEEPEMANQALLKHR 149
Query: 256 NNMQHRYIELF 266
+ +RYIE+F
Sbjct: 150 EEIGNRYIEIF 160
Score = 44.7 bits (104), Expect = 1e-04
Identities = 19/69 (27%), Positives = 39/69 (56%), Gaps = 2/69 (2%)
Query: 30 EEIVQFFQGLEIV--PNGITLTMDYQGRSTGEAFVQFASKEIAENALGKHKERIGHRYIE 87
E+++ FF I NGI ++ G+ G+A ++ S++ + AL KH+ +G RY+E
Sbjct: 2 EDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALEKHRMYMGQRYVE 61
Query: 88 IFRSSRSEI 96
++ + ++
Sbjct: 62 VYEINNEDV 70
Score = 37.0 bits (84), Expect = 0.026
Identities = 20/62 (32%), Positives = 33/62 (53%), Gaps = 6/62 (9%)
Query: 210 DIANFFSPLNPIR-----VHIDIGADGRATGEADVEFVTHEDAVAAMSKDKNNMQHRYIE 264
D+ NFFS IR +H + DG+ G+A +E + +D A+ K + M RY+E
Sbjct: 3 DVLNFFSDCR-IRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALEKHRMYMGQRYVE 61
Query: 265 LF 266
++
Sbjct: 62 VY 63
>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
[Homo sapiens]
Length = 526
Score = 82.8 bits (203), Expect = 4e-16
Identities = 84/298 (28%), Positives = 110/298 (36%), Gaps = 73/298 (24%)
Query: 100 YDPPRRLLGQRPGPYDRPIGGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNNY 159
Y+PP+ GQ+ Y+ GG GG G G G G GGYG D GG +
Sbjct: 149 YNPPQGY-GQQ-NQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSG 206
Query: 160 GYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFH--------------------------G 193
GYG R R G G GG G GG + SSG + G
Sbjct: 207 GYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFG 266
Query: 194 G-----------------HFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGAD------ 230
G + + ++GL T +A++F + I+ + G
Sbjct: 267 GPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYT 326
Query: 231 ----GRATGEADVEFVTHEDAVAAMSK-DKNNMQHRYIELFLNSTPGGGSGMGGSGMGGY 285
G+ GEA V F A AA+ D I++ + + GG+G GG
Sbjct: 327 DRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGR 386
Query: 286 GRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGSGGYYGQGGMSGGGWR 343
GR G +GGYG GG G GG GRGG SGG G G G W+
Sbjct: 387 GRGGPMGRGGYG------------GG-----GSGGGGRGGFPSGGGGGGGQQRAGDWK 427
Score = 57.8 bits (138), Expect = 1e-08
Identities = 44/104 (42%), Positives = 50/104 (48%), Gaps = 32/104 (30%)
Query: 268 NSTPGGGSGMGGSGMGGYGRD------GMDNQGGYGSVGRMGMGNNYSGGYGTPD----G 317
NS+ GGG G GG G YG+D G + GGYG+ + G G SGGYG D G
Sbjct: 162 NSSSGGGGGGGGGG--NYGQDQSSMSSGGGSGGGYGNQDQSGGGG--SGGYGQQDRGGRG 217
Query: 318 LGGYGRGGGGSGGYY-----------------GQGGMSGGGWRG 344
GG G GGGG GG Y G+GGM GG RG
Sbjct: 218 RGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGM-GGSDRG 260
Score = 48.5 bits (114), Expect = 9e-06
Identities = 85/340 (25%), Positives = 113/340 (33%), Gaps = 108/340 (31%)
Query: 6 KHNGPNDASDG-TVRLRGLPFGCSKEEIVQFFQGLEIVPNG-------ITLTMDYQ-GRS 56
+H+ D SD T+ ++GL + E + +F+ + I+ I L D + G+
Sbjct: 274 RHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKL 333
Query: 57 TGEAFVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDR 116
GEA V F A+ A+ + E G +P + R ++R
Sbjct: 334 KGEATVSFDDPPSAKAAIDWFDGK--------------EFSG--NPIKVSFATRRADFNR 377
Query: 117 PIGGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDRMRDGRGM 176
GG G G GRG R GGYGG
Sbjct: 378 --GGGNGRGGRGRGGPMGR---------GGYGG--------------------------- 399
Query: 177 GGHGYGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGE 236
GG G GG G SG GG G RA G+
Sbjct: 400 GGSGGGGRGGFPSGGGGG---------------------------------GGQQRA-GD 425
Query: 237 ADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSGMGG-YGRDGMDNQGG 295
T E+ + + N + G G G GGS MGG YG D +GG
Sbjct: 426 WKCPNPTCENMNFSWRNECNQCK-------APKPDGPGGGPGGSHMGGNYGDDRRGGRGG 478
Query: 296 YGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGSGGYYGQG 335
Y G G G + G G G GG RGG G G +G
Sbjct: 479 YDRGGYRGRGGDRGGFRG---GRGGGDRGGFGPGKMDSRG 515
Score = 42.4 bits (98), Expect = 6e-04
Identities = 24/53 (45%), Positives = 27/53 (50%), Gaps = 6/53 (11%)
Query: 300 GRMGMGNNYSGGYGTPDGLGGYGR------GGGGSGGYYGQGGMSGGGWRGMY 346
G+ N+ SGG G G G YG+ GGGSGG YG SGGG G Y
Sbjct: 156 GQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGY 208
Score = 38.5 bits (88), Expect = 0.009
Identities = 28/75 (37%), Positives = 29/75 (38%), Gaps = 19/75 (25%)
Query: 289 GMDNQGGYGSVGRMGMGNNYSGGYGTPDGL--------GGYGR----GGGGSGGY----- 331
G Q Y S G G G YG GGYG GGGGSGGY
Sbjct: 154 GYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDR 213
Query: 332 --YGQGGMSGGGWRG 344
G+GG GGG G
Sbjct: 214 GGRGRGGSGGGGGGG 228
Score = 38.1 bits (87), Expect = 0.012
Identities = 35/90 (38%), Positives = 37/90 (41%), Gaps = 16/90 (17%)
Query: 115 DRPIGGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDRMRDGR 174
D P GG GG + G Y RRGG GGY D GGY G GF R GR
Sbjct: 453 DGPGGGPGGSH---MGGNYGDDRRGG---RGGY----DRGGYRGRGGDRGGF----RGGR 498
Query: 175 GMGGHGYGGAGDASSGFHGGHFVHMRGLPF 204
G G G G G S G H R P+
Sbjct: 499 GGGDRGGFGPGKMDS--RGEHRQDRRERPY 526
Score = 36.2 bits (82), Expect = 0.044
Identities = 31/125 (24%), Positives = 38/125 (30%), Gaps = 51/125 (40%)
Query: 269 STPGGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGR----- 323
STP G GG G + Q Y G+ ++ SG YG+ YG+
Sbjct: 70 STPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGS 129
Query: 324 ---------------------------------------GGGGSGGYYGQ-------GGM 337
GGGG GG YGQ GG
Sbjct: 130 YSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGG 189
Query: 338 SGGGW 342
SGGG+
Sbjct: 190 SGGGY 194
Score = 31.6 bits (70), Expect = 1.1
Identities = 27/93 (29%), Positives = 36/93 (38%), Gaps = 11/93 (11%)
Query: 108 GQRPGPYDRPIGGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDD-YGGYNNYGYGNDGF 166
GQ+P P G Y + + S Y + + G YGG YG +Y G+
Sbjct: 101 GQQPAPSSTS----GSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYN-PPQGY 155
Query: 167 DDRMRDGRGMGGHGYGGAG-----DASSGFHGG 194
+ + GG G GG G D SS GG
Sbjct: 156 GQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGG 188
Score = 30.4 bits (67), Expect = 2.4
Identities = 20/62 (32%), Positives = 24/62 (38%), Gaps = 7/62 (11%)
Query: 278 GGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGG-----GSGGYY 332
G GY + + GYG G + + GYGT GYG GG S Y
Sbjct: 34 GQQSYSGYSQS--TDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSY 91
Query: 333 GQ 334
GQ
Sbjct: 92 GQ 93
Score = 29.3 bits (64), Expect = 5.4
Identities = 28/100 (28%), Positives = 32/100 (32%), Gaps = 21/100 (21%)
Query: 268 NSTPGGGSGMGGSGMGG-YGRDGMDNQGGYGSVGRMGMGNNYSG---------GYGTPDG 317
+S PG G S G YG + G G +Y G Y P G
Sbjct: 95 SSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQG 154
Query: 318 LGGYGRGGGGSGGYYGQGG-----------MSGGGWRGMY 346
G + SGG G GG SGGG G Y
Sbjct: 155 YGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGY 194
>gi|170763533 RNA binding motif protein 35A isoform 5 [Homo sapiens]
Length = 604
Score = 76.3 bits (186), Expect = 4e-14
Identities = 42/83 (50%), Positives = 55/83 (66%), Gaps = 3/83 (3%)
Query: 18 VRLRGLPFGCSKEEIVQFF-QGLEIV--PNGITLTMDYQGRSTGEAFVQFASKEIAENAL 74
VR+RGLPF + EE+V FF Q I GI GR TG+AFV FA +E A+NAL
Sbjct: 328 VRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNAL 387
Query: 75 GKHKERIGHRYIEIFRSSRSEIK 97
KHK+ +G RYIE+FRS+ +E++
Sbjct: 388 RKHKDLLGKRYIELFRSTAAEVQ 410
Score = 73.2 bits (178), Expect = 3e-13
Identities = 34/75 (45%), Positives = 51/75 (68%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
VR RGLP+ S ++I +FF+GL I G L ++ QGR GEA V+F S+E + AL +H
Sbjct: 227 VRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRH 286
Query: 78 KERIGHRYIEIFRSS 92
K +G RYIE+++++
Sbjct: 287 KHHMGTRYIEVYKAT 301
Score = 58.5 bits (140), Expect = 8e-09
Identities = 30/82 (36%), Positives = 52/82 (63%), Gaps = 3/82 (3%)
Query: 18 VRLRGLPFGCSKEEIVQFFQ--GLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALG 75
+RLRGLP+ + E+I+ F +I +G+ + +++QGR +G+AF+Q S + A A
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQ 506
Query: 76 K-HKERIGHRYIEIFRSSRSEI 96
K HK+ + RY+E+F+ S E+
Sbjct: 507 KCHKKNMKDRYVEVFQCSAEEM 528
Score = 53.9 bits (128), Expect = 2e-07
Identities = 29/72 (40%), Positives = 44/72 (61%), Gaps = 2/72 (2%)
Query: 197 VHMRGLPFRATENDIANFFSPLNPIR--VHIDIGADGRATGEADVEFVTHEDAVAAMSKD 254
V RGLP+++++ DIA FF LN + + + A GR GEA V FV+ E A+ +
Sbjct: 227 VRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRH 286
Query: 255 KNNMQHRYIELF 266
K++M RYIE++
Sbjct: 287 KHHMGTRYIEVY 298
Score = 50.1 bits (118), Expect = 3e-06
Identities = 32/75 (42%), Positives = 39/75 (52%), Gaps = 5/75 (6%)
Query: 197 VHMRGLPFRATENDIANFFSPLNPIR-----VHIDIGADGRATGEADVEFVTHEDAVAAM 251
V MRGLPF AT ++ FF PI + DGR TG+A V F E A A+
Sbjct: 328 VRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNAL 387
Query: 252 SKDKNNMQHRYIELF 266
K K+ + RYIELF
Sbjct: 388 RKHKDLLGKRYIELF 402
Score = 44.7 bits (104), Expect = 1e-04
Identities = 25/75 (33%), Positives = 43/75 (57%), Gaps = 5/75 (6%)
Query: 197 VHMRGLPFRATENDIANFF----SPLNPIRVHIDIGADGRATGEADVEFVTHEDA-VAAM 251
+ +RGLP+ AT DI +F + + VH+ + GR +G+A ++ + + A +AA
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQ 506
Query: 252 SKDKNNMQHRYIELF 266
K NM+ RY+E+F
Sbjct: 507 KCHKKNMKDRYVEVF 521
>gi|170763529 RNA binding motif protein 35A isoform 3 [Homo sapiens]
Length = 659
Score = 76.3 bits (186), Expect = 4e-14
Identities = 42/83 (50%), Positives = 55/83 (66%), Gaps = 3/83 (3%)
Query: 18 VRLRGLPFGCSKEEIVQFF-QGLEIV--PNGITLTMDYQGRSTGEAFVQFASKEIAENAL 74
VR+RGLPF + EE+V FF Q I GI GR TG+AFV FA +E A+NAL
Sbjct: 328 VRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNAL 387
Query: 75 GKHKERIGHRYIEIFRSSRSEIK 97
KHK+ +G RYIE+FRS+ +E++
Sbjct: 388 RKHKDLLGKRYIELFRSTAAEVQ 410
Score = 73.2 bits (178), Expect = 3e-13
Identities = 34/75 (45%), Positives = 51/75 (68%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
VR RGLP+ S ++I +FF+GL I G L ++ QGR GEA V+F S+E + AL +H
Sbjct: 227 VRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRH 286
Query: 78 KERIGHRYIEIFRSS 92
K +G RYIE+++++
Sbjct: 287 KHHMGTRYIEVYKAT 301
Score = 58.5 bits (140), Expect = 8e-09
Identities = 30/82 (36%), Positives = 52/82 (63%), Gaps = 3/82 (3%)
Query: 18 VRLRGLPFGCSKEEIVQFFQ--GLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALG 75
+RLRGLP+ + E+I+ F +I +G+ + +++QGR +G+AF+Q S + A A
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQ 506
Query: 76 K-HKERIGHRYIEIFRSSRSEI 96
K HK+ + RY+E+F+ S E+
Sbjct: 507 KCHKKNMKDRYVEVFQCSAEEM 528
Score = 53.9 bits (128), Expect = 2e-07
Identities = 29/72 (40%), Positives = 44/72 (61%), Gaps = 2/72 (2%)
Query: 197 VHMRGLPFRATENDIANFFSPLNPIR--VHIDIGADGRATGEADVEFVTHEDAVAAMSKD 254
V RGLP+++++ DIA FF LN + + + A GR GEA V FV+ E A+ +
Sbjct: 227 VRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRH 286
Query: 255 KNNMQHRYIELF 266
K++M RYIE++
Sbjct: 287 KHHMGTRYIEVY 298
Score = 50.1 bits (118), Expect = 3e-06
Identities = 32/75 (42%), Positives = 39/75 (52%), Gaps = 5/75 (6%)
Query: 197 VHMRGLPFRATENDIANFFSPLNPIR-----VHIDIGADGRATGEADVEFVTHEDAVAAM 251
V MRGLPF AT ++ FF PI + DGR TG+A V F E A A+
Sbjct: 328 VRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNAL 387
Query: 252 SKDKNNMQHRYIELF 266
K K+ + RYIELF
Sbjct: 388 RKHKDLLGKRYIELF 402
Score = 44.7 bits (104), Expect = 1e-04
Identities = 25/75 (33%), Positives = 43/75 (57%), Gaps = 5/75 (6%)
Query: 197 VHMRGLPFRATENDIANFF----SPLNPIRVHIDIGADGRATGEADVEFVTHEDA-VAAM 251
+ +RGLP+ AT DI +F + + VH+ + GR +G+A ++ + + A +AA
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQ 506
Query: 252 SKDKNNMQHRYIELF 266
K NM+ RY+E+F
Sbjct: 507 KCHKKNMKDRYVEVF 521
>gi|170763527 RNA binding motif protein 35A isoform 4 [Homo sapiens]
Length = 608
Score = 76.3 bits (186), Expect = 4e-14
Identities = 42/83 (50%), Positives = 55/83 (66%), Gaps = 3/83 (3%)
Query: 18 VRLRGLPFGCSKEEIVQFF-QGLEIV--PNGITLTMDYQGRSTGEAFVQFASKEIAENAL 74
VR+RGLPF + EE+V FF Q I GI GR TG+AFV FA +E A+NAL
Sbjct: 328 VRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNAL 387
Query: 75 GKHKERIGHRYIEIFRSSRSEIK 97
KHK+ +G RYIE+FRS+ +E++
Sbjct: 388 RKHKDLLGKRYIELFRSTAAEVQ 410
Score = 73.2 bits (178), Expect = 3e-13
Identities = 34/75 (45%), Positives = 51/75 (68%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
VR RGLP+ S ++I +FF+GL I G L ++ QGR GEA V+F S+E + AL +H
Sbjct: 227 VRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRH 286
Query: 78 KERIGHRYIEIFRSS 92
K +G RYIE+++++
Sbjct: 287 KHHMGTRYIEVYKAT 301
Score = 59.7 bits (143), Expect = 4e-09
Identities = 37/114 (32%), Positives = 60/114 (52%), Gaps = 14/114 (12%)
Query: 18 VRLRGLPFGCSKEEIVQFFQ--GLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALG 75
+RLRGLP+ + E+I+ F +I +G+ + +++QGR +G+AF+Q S + A A
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQ 506
Query: 76 K-HKERIGHRYIEIFRSSRSEI-----------KGFYDPPRRLLGQRPGPYDRP 117
K HK+ + RY+E+F+ S E+ G PP +L P Y P
Sbjct: 507 KCHKKNMKDRYVEVFQCSAEEMNFVLMGGTLNRNGLSPPPCKLPCLSPPSYTFP 560
Score = 53.9 bits (128), Expect = 2e-07
Identities = 29/72 (40%), Positives = 44/72 (61%), Gaps = 2/72 (2%)
Query: 197 VHMRGLPFRATENDIANFFSPLNPIR--VHIDIGADGRATGEADVEFVTHEDAVAAMSKD 254
V RGLP+++++ DIA FF LN + + + A GR GEA V FV+ E A+ +
Sbjct: 227 VRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRH 286
Query: 255 KNNMQHRYIELF 266
K++M RYIE++
Sbjct: 287 KHHMGTRYIEVY 298
Score = 50.1 bits (118), Expect = 3e-06
Identities = 32/75 (42%), Positives = 39/75 (52%), Gaps = 5/75 (6%)
Query: 197 VHMRGLPFRATENDIANFFSPLNPIR-----VHIDIGADGRATGEADVEFVTHEDAVAAM 251
V MRGLPF AT ++ FF PI + DGR TG+A V F E A A+
Sbjct: 328 VRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNAL 387
Query: 252 SKDKNNMQHRYIELF 266
K K+ + RYIELF
Sbjct: 388 RKHKDLLGKRYIELF 402
Score = 44.7 bits (104), Expect = 1e-04
Identities = 25/75 (33%), Positives = 43/75 (57%), Gaps = 5/75 (6%)
Query: 197 VHMRGLPFRATENDIANFF----SPLNPIRVHIDIGADGRATGEADVEFVTHEDA-VAAM 251
+ +RGLP+ AT DI +F + + VH+ + GR +G+A ++ + + A +AA
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQ 506
Query: 252 SKDKNNMQHRYIELF 266
K NM+ RY+E+F
Sbjct: 507 KCHKKNMKDRYVEVF 521
>gi|170763525 RNA binding motif protein 35A isoform 2 [Homo sapiens]
Length = 677
Score = 76.3 bits (186), Expect = 4e-14
Identities = 42/83 (50%), Positives = 55/83 (66%), Gaps = 3/83 (3%)
Query: 18 VRLRGLPFGCSKEEIVQFF-QGLEIV--PNGITLTMDYQGRSTGEAFVQFASKEIAENAL 74
VR+RGLPF + EE+V FF Q I GI GR TG+AFV FA +E A+NAL
Sbjct: 328 VRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNAL 387
Query: 75 GKHKERIGHRYIEIFRSSRSEIK 97
KHK+ +G RYIE+FRS+ +E++
Sbjct: 388 RKHKDLLGKRYIELFRSTAAEVQ 410
Score = 73.2 bits (178), Expect = 3e-13
Identities = 34/75 (45%), Positives = 51/75 (68%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
VR RGLP+ S ++I +FF+GL I G L ++ QGR GEA V+F S+E + AL +H
Sbjct: 227 VRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRH 286
Query: 78 KERIGHRYIEIFRSS 92
K +G RYIE+++++
Sbjct: 287 KHHMGTRYIEVYKAT 301
Score = 58.5 bits (140), Expect = 8e-09
Identities = 30/82 (36%), Positives = 52/82 (63%), Gaps = 3/82 (3%)
Query: 18 VRLRGLPFGCSKEEIVQFFQ--GLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALG 75
+RLRGLP+ + E+I+ F +I +G+ + +++QGR +G+AF+Q S + A A
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQ 506
Query: 76 K-HKERIGHRYIEIFRSSRSEI 96
K HK+ + RY+E+F+ S E+
Sbjct: 507 KCHKKNMKDRYVEVFQCSAEEM 528
Score = 53.9 bits (128), Expect = 2e-07
Identities = 29/72 (40%), Positives = 44/72 (61%), Gaps = 2/72 (2%)
Query: 197 VHMRGLPFRATENDIANFFSPLNPIR--VHIDIGADGRATGEADVEFVTHEDAVAAMSKD 254
V RGLP+++++ DIA FF LN + + + A GR GEA V FV+ E A+ +
Sbjct: 227 VRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRH 286
Query: 255 KNNMQHRYIELF 266
K++M RYIE++
Sbjct: 287 KHHMGTRYIEVY 298
Score = 50.1 bits (118), Expect = 3e-06
Identities = 32/75 (42%), Positives = 39/75 (52%), Gaps = 5/75 (6%)
Query: 197 VHMRGLPFRATENDIANFFSPLNPIR-----VHIDIGADGRATGEADVEFVTHEDAVAAM 251
V MRGLPF AT ++ FF PI + DGR TG+A V F E A A+
Sbjct: 328 VRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNAL 387
Query: 252 SKDKNNMQHRYIELF 266
K K+ + RYIELF
Sbjct: 388 RKHKDLLGKRYIELF 402
Score = 44.7 bits (104), Expect = 1e-04
Identities = 25/75 (33%), Positives = 43/75 (57%), Gaps = 5/75 (6%)
Query: 197 VHMRGLPFRATENDIANFF----SPLNPIRVHIDIGADGRATGEADVEFVTHEDA-VAAM 251
+ +RGLP+ AT DI +F + + VH+ + GR +G+A ++ + + A +AA
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQ 506
Query: 252 SKDKNNMQHRYIELF 266
K NM+ RY+E+F
Sbjct: 507 KCHKKNMKDRYVEVF 521
>gi|56790297 RNA binding motif protein 35A isoform 1 [Homo sapiens]
Length = 681
Score = 76.3 bits (186), Expect = 4e-14
Identities = 42/83 (50%), Positives = 55/83 (66%), Gaps = 3/83 (3%)
Query: 18 VRLRGLPFGCSKEEIVQFF-QGLEIV--PNGITLTMDYQGRSTGEAFVQFASKEIAENAL 74
VR+RGLPF + EE+V FF Q I GI GR TG+AFV FA +E A+NAL
Sbjct: 328 VRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNAL 387
Query: 75 GKHKERIGHRYIEIFRSSRSEIK 97
KHK+ +G RYIE+FRS+ +E++
Sbjct: 388 RKHKDLLGKRYIELFRSTAAEVQ 410
Score = 73.2 bits (178), Expect = 3e-13
Identities = 34/75 (45%), Positives = 51/75 (68%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
VR RGLP+ S ++I +FF+GL I G L ++ QGR GEA V+F S+E + AL +H
Sbjct: 227 VRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRH 286
Query: 78 KERIGHRYIEIFRSS 92
K +G RYIE+++++
Sbjct: 287 KHHMGTRYIEVYKAT 301
Score = 59.7 bits (143), Expect = 4e-09
Identities = 37/114 (32%), Positives = 60/114 (52%), Gaps = 14/114 (12%)
Query: 18 VRLRGLPFGCSKEEIVQFFQ--GLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALG 75
+RLRGLP+ + E+I+ F +I +G+ + +++QGR +G+AF+Q S + A A
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQ 506
Query: 76 K-HKERIGHRYIEIFRSSRSEI-----------KGFYDPPRRLLGQRPGPYDRP 117
K HK+ + RY+E+F+ S E+ G PP +L P Y P
Sbjct: 507 KCHKKNMKDRYVEVFQCSAEEMNFVLMGGTLNRNGLSPPPCKLPCLSPPSYTFP 560
Score = 53.9 bits (128), Expect = 2e-07
Identities = 29/72 (40%), Positives = 44/72 (61%), Gaps = 2/72 (2%)
Query: 197 VHMRGLPFRATENDIANFFSPLNPIR--VHIDIGADGRATGEADVEFVTHEDAVAAMSKD 254
V RGLP+++++ DIA FF LN + + + A GR GEA V FV+ E A+ +
Sbjct: 227 VRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRH 286
Query: 255 KNNMQHRYIELF 266
K++M RYIE++
Sbjct: 287 KHHMGTRYIEVY 298
Score = 50.1 bits (118), Expect = 3e-06
Identities = 32/75 (42%), Positives = 39/75 (52%), Gaps = 5/75 (6%)
Query: 197 VHMRGLPFRATENDIANFFSPLNPIR-----VHIDIGADGRATGEADVEFVTHEDAVAAM 251
V MRGLPF AT ++ FF PI + DGR TG+A V F E A A+
Sbjct: 328 VRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNAL 387
Query: 252 SKDKNNMQHRYIELF 266
K K+ + RYIELF
Sbjct: 388 RKHKDLLGKRYIELF 402
Score = 44.7 bits (104), Expect = 1e-04
Identities = 25/75 (33%), Positives = 43/75 (57%), Gaps = 5/75 (6%)
Query: 197 VHMRGLPFRATENDIANFF----SPLNPIRVHIDIGADGRATGEADVEFVTHEDA-VAAM 251
+ +RGLP+ AT DI +F + + VH+ + GR +G+A ++ + + A +AA
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQ 506
Query: 252 SKDKNNMQHRYIELF 266
K NM+ RY+E+F
Sbjct: 507 KCHKKNMKDRYVEVF 521
>gi|45935393 RNA binding motif protein 35B [Homo sapiens]
Length = 717
Score = 73.6 bits (179), Expect = 3e-13
Identities = 32/82 (39%), Positives = 53/82 (64%)
Query: 14 SDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENA 73
S+ VR RGLP+ S +++ +FF+GL + G+ L ++ QGR GEA ++F E + A
Sbjct: 245 SETVVRARGLPWQSSDQDVARFFKGLNVARGGVALCLNAQGRRNGEALIRFVDSEQRDLA 304
Query: 74 LGKHKERIGHRYIEIFRSSRSE 95
L +HK +G RYIE+++++ E
Sbjct: 305 LQRHKHHMGVRYIEVYKATGEE 326
Score = 62.4 bits (150), Expect = 6e-10
Identities = 35/84 (41%), Positives = 52/84 (61%), Gaps = 5/84 (5%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDY----QGRSTGEAFVQFASKEIAENA 73
+RLRGLPF +++ F G E G T + + GR TG+AF FA +E+A+ A
Sbjct: 350 LRLRGLPFSAGPTDVLGFL-GPECPVTGGTEGLLFVRHPDGRPTGDAFALFACEELAQAA 408
Query: 74 LGKHKERIGHRYIEIFRSSRSEIK 97
L +HK +G RYIE+FRS+ +E++
Sbjct: 409 LRRHKGMLGKRYIELFRSTAAEVQ 432
Score = 56.2 bits (134), Expect = 4e-08
Identities = 31/82 (37%), Positives = 50/82 (60%), Gaps = 3/82 (3%)
Query: 18 VRLRGLPFGCSKEEIVQFF--QGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALG 75
VRLRGLP+ + E+I+ F +I P+G+ + ++ QGR +G+AF+Q S E A A
Sbjct: 467 VRLRGLPYTATIEDILSFLGEAAADIRPHGVHMVLNQQGRPSGDAFIQMTSAERALAAAQ 526
Query: 76 K-HKERIGHRYIEIFRSSRSEI 96
+ HK+ + RY+E+ S E+
Sbjct: 527 RCHKKVMKERYVEVVPCSTEEM 548
Score = 55.1 bits (131), Expect = 9e-08
Identities = 29/72 (40%), Positives = 44/72 (61%), Gaps = 2/72 (2%)
Query: 197 VHMRGLPFRATENDIANFFSPLNPIR--VHIDIGADGRATGEADVEFVTHEDAVAAMSKD 254
V RGLP+++++ D+A FF LN R V + + A GR GEA + FV E A+ +
Sbjct: 249 VRARGLPWQSSDQDVARFFKGLNVARGGVALCLNAQGRRNGEALIRFVDSEQRDLALQRH 308
Query: 255 KNNMQHRYIELF 266
K++M RYIE++
Sbjct: 309 KHHMGVRYIEVY 320
Score = 50.1 bits (118), Expect = 3e-06
Identities = 35/103 (33%), Positives = 53/103 (51%), Gaps = 8/103 (7%)
Query: 193 GGHFVHMRGLPFRATENDIANFF----SPLNPIRVHIDIGADGRATGEADVEFVTHEDAV 248
G V +RGLP+ AT DI +F + + P VH+ + GR +G+A ++ + E A+
Sbjct: 463 GRDCVRLRGLPYTATIEDILSFLGEAAADIRPHGVHMVLNQQGRPSGDAFIQMTSAERAL 522
Query: 249 AAMSK-DKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDGM 290
AA + K M+ RY+E+ ST + G G GR GM
Sbjct: 523 AAAQRCHKKVMKERYVEVVPCSTEEMSRVLMG---GTLGRSGM 562
Score = 45.8 bits (107), Expect = 6e-05
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 5/75 (6%)
Query: 197 VHMRGLPFRATENDIANFFSPLNPIRVHID-----IGADGRATGEADVEFVTHEDAVAAM 251
+ +RGLPF A D+ F P P+ + DGR TG+A F E A AA+
Sbjct: 350 LRLRGLPFSAGPTDVLGFLGPECPVTGGTEGLLFVRHPDGRPTGDAFALFACEELAQAAL 409
Query: 252 SKDKNNMQHRYIELF 266
+ K + RYIELF
Sbjct: 410 RRHKGMLGKRYIELF 424
>gi|118722349 RNA binding motif protein 12B [Homo sapiens]
Length = 1001
Score = 73.6 bits (179), Expect = 3e-13
Identities = 71/254 (27%), Positives = 111/254 (43%), Gaps = 31/254 (12%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
+RL GLPF +I FF GL I G+ + G GEAF+ FA+ E A A+ +
Sbjct: 5 IRLLGLPFIAGPVDIRHFFTGLTIPDGGVHII----GGEIGEAFIIFATDEDARRAISRS 60
Query: 78 KERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGRGSMYDRMR 137
I +E+F SS++E++ + R DR GR G +G S+ + +
Sbjct: 61 GGFIKDSSVELFLSSKAEMQKTIEMKRT---------DRVGRGRPGSGTSGVDSLSNFIE 111
Query: 138 R-GGDGYDGGYG-GFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGH 195
+ + GYG + G++ G G+ R R R +
Sbjct: 112 SVKEEASNSGYGSSINQDAGFHTNGTGHGNL--RPRKTRPLKAE--------------NP 155
Query: 196 FVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDK 255
++ +RGLP+ E+D+ FFS L V DGR G+A V+F + DA + +
Sbjct: 156 YLFLRGLPYLVNEDDVRVFFSGLCVDGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHR 215
Query: 256 NNMQHRYIELFLNS 269
+ M R+IE+ S
Sbjct: 216 SFMGSRFIEVMQGS 229
Score = 53.1 bits (126), Expect = 4e-07
Identities = 61/258 (23%), Positives = 101/258 (39%), Gaps = 53/258 (20%)
Query: 10 PNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEI 69
P A + + LRGLP+ +++++ FF GL + +G+ + GR+ G+A V+FAS
Sbjct: 149 PLKAENPYLFLRGLPYLVNEDDVRVFFSGLCV--DGVIFLKHHDGRNNGDAIVKFASCVD 206
Query: 70 AENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGR 129
A L H+ +G R+IE+ + S + F GG G
Sbjct: 207 ASGGLKCHRSFMGSRFIEVMQGSEQQWIEF-------------------GGNAVKEG--- 244
Query: 130 GSMYDRMRRGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASS 189
D +RR + G N+ + R R G+
Sbjct: 245 ----DVLRRSEE--------HSPPRGINDRHFRKRSHSKSPRRTRSRSPLGF-------- 284
Query: 190 GFHGGHFVHMRGLPFRATENDIANFF--SPLNPIRVHIDIGADGRATGEADVEFVTHEDA 247
+VH++ L E D+ NFF + L ++ + D T A V F T +D
Sbjct: 285 ------YVHLKNLSLSIDERDLRNFFRGTDLTDEQIRF-LYKDENRTRYAFVMFKTLKDY 337
Query: 248 VAAMSKDKNNMQHRYIEL 265
A+S K +Q+R + +
Sbjct: 338 NTALSLHKTVLQYRPVHI 355
Score = 43.9 bits (102), Expect = 2e-04
Identities = 22/72 (30%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
+++ LPF + EI+ FF G I+P+ +++ + QG TGEA V + A A+
Sbjct: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAIKDL 986
Query: 78 KER-IGHRYIEI 88
+R +G R +++
Sbjct: 987 NDRPVGPRKVKL 998
Score = 38.9 bits (89), Expect = 0.007
Identities = 24/82 (29%), Positives = 41/82 (50%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
+ +R PF +K E+ +FF + + I L D +G GEA V+F S+E A A +
Sbjct: 402 IYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKSEEQAMKAERLN 461
Query: 78 KERIGHRYIEIFRSSRSEIKGF 99
+ R + + S ++I+ F
Sbjct: 462 RRRFLGTEVLLRLISEAQIQEF 483
Score = 37.7 bits (86), Expect = 0.015
Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 3/63 (4%)
Query: 197 VHMRGLPFRATENDIANFFS--PLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKD 254
+ + LPF+A N+I +FF + P V I G TGEA V + + +A+AA+ KD
Sbjct: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAI-KD 985
Query: 255 KNN 257
N+
Sbjct: 986 LND 988
Score = 33.1 bits (74), Expect = 0.38
Identities = 28/100 (28%), Positives = 44/100 (44%), Gaps = 6/100 (6%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
V L+ L + ++ FF+G ++ I + R T AFV F + + AL H
Sbjct: 286 VHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKDENR-TRYAFVMFKTLKDYNTALSLH 344
Query: 78 KERIGHRYIEIFRSSRSEIKGF---YDPPR--RLLGQRPG 112
K + +R + I SR ++ F Y+ R L RPG
Sbjct: 345 KTVLQYRPVHIDPISRKQMLKFIARYEKKRSGSLERDRPG 384
>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
Length = 589
Score = 70.9 bits (172), Expect = 2e-12
Identities = 84/312 (26%), Positives = 115/312 (36%), Gaps = 71/312 (22%)
Query: 70 AENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGR 129
++N H +R Y + R ++ + + R G + G GRGGY GR
Sbjct: 140 SQNQQSYHSQR--ENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGR-----GRGGYDKDGR 192
Query: 130 GSMYDRMRRGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASS 189
G M G G G GGF ++GG+ +YG D D+ S
Sbjct: 193 GPM-----TGSSG--GDRGGFKNFGGHRDYGPRTD--------------------ADSES 225
Query: 190 GFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGA----------DGRATGEADV 239
+ + ++GL + + + FF + I+ + G G+ GEA V
Sbjct: 226 DNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATV 285
Query: 240 EFVTHEDAVAAMS-KDKNNMQHRYIEL-FLNSTP----GGGSGMGGSGMGGY-GRDGMDN 292
F A AA+ D I++ F P GGGSG G G GGY GR G
Sbjct: 286 SFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQG 345
Query: 293 QGG----------YGSVGRMGMGNNYSGGY--------GTPDGLGGYGRGGGGSGGYYGQ 334
+GG S G M S P G GRG GG GY G+
Sbjct: 346 RGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGR 405
Query: 335 GGMSG--GGWRG 344
GG G GG+ G
Sbjct: 406 GGRGGDRGGYGG 417
Score = 70.1 bits (170), Expect = 3e-12
Identities = 114/397 (28%), Positives = 141/397 (35%), Gaps = 113/397 (28%)
Query: 11 NDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNG-------ITLTMDYQ-GRSTGEAFV 62
+++ + T+ ++GL G S +++ +FF+ + I+ I L D G+ GEA V
Sbjct: 226 DNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATV 285
Query: 63 QFASKEIAENALG--KHKERIGHRYIEIFRSSRSEI------------KGFY-------- 100
F A+ A+ KE G+ F + R E +G Y
Sbjct: 286 SFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQG 345
Query: 101 ---DP-------PRRLLGQ-------------RPGPYD-RPIGG--RGGYYGAGRGSMYD 134
DP P G P P D RP GG RG YG RG
Sbjct: 346 RGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGY--- 402
Query: 135 RMRRGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGG--AGDASSGFH 192
R R G G GGYGG D GG GYG D G GG GYGG +G G
Sbjct: 403 RGRGGRGGDRGGYGG-DRSGG----GYGGDRSSGGGYSGDRSGG-GYGGDRSGGGYGGDR 456
Query: 193 GGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMS 252
GG + RG + G D G D
Sbjct: 457 GGGYGGDRGGGYGGDRGG---------------GYGGDRGGYGG---------DRGGGYG 492
Query: 253 KDKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRD-----GMDNQGGYGSV--GRMGMG 305
D+ GG G G GGYG D G ++GGYG G G G
Sbjct: 493 GDRGGY-------------GGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYG 539
Query: 306 NNYSGGYGTPDGLGGYG--RGGGGSGGYYGQGGMSGG 340
+ SGGYG GGYG RGGG G G GG GG
Sbjct: 540 GDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGG 576
Score = 59.7 bits (143), Expect = 4e-09
Identities = 72/225 (32%), Positives = 81/225 (36%), Gaps = 47/225 (20%)
Query: 116 RPIGGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGG-----YNNYGYGNDGFDDRM 170
R GG GY G G G DR GGD GGYGG GG + GYG D
Sbjct: 394 RGYGGERGYRGRG-GRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGD------ 446
Query: 171 RDGRGMGGH---GYGG-AGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHID 226
R G G GG GYGG G G GG + RG D + D
Sbjct: 447 RSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRG----GYGGDRGGGYGG--------D 494
Query: 227 IGADGRATGEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYG 286
G G G + + D++ + GGGSG GG GGYG
Sbjct: 495 RGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGY-------GGDRGGGSGYGGDRSGGYG 547
Query: 287 RDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGSGGY 331
D GG G G + GGYG GGYG GG Y
Sbjct: 548 GD---RSGG-------GYGGDRGGGYG--GDRGGYGGKMGGRNDY 580
Score = 52.8 bits (125), Expect = 5e-07
Identities = 34/74 (45%), Positives = 37/74 (50%), Gaps = 4/74 (5%)
Query: 274 GSGMGGSGMGGYGRDGMDNQGGYGSV-GRMGMGNNYSGGYGTPDGLGGYG--RGGGGSGG 330
G G GG G G G + GGYG G G + GGYG G GGYG RGGG G
Sbjct: 421 GGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRG-GGYGGDRGGGYGGD 479
Query: 331 YYGQGGMSGGGWRG 344
G GG GGG+ G
Sbjct: 480 RGGYGGDRGGGYGG 493
Score = 48.9 bits (115), Expect = 7e-06
Identities = 38/84 (45%), Positives = 39/84 (46%), Gaps = 15/84 (17%)
Query: 274 GSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSG-----GYGTPDGLGGYG--RGGG 326
G G G GGYG D + GGYG G G YSG GYG GGYG RGGG
Sbjct: 404 GRGGRGGDRGGYGGDR--SGGGYG--GDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGG 459
Query: 327 ----GSGGYYGQGGMSGGGWRGMY 346
GGY G G GG RG Y
Sbjct: 460 YGGDRGGGYGGDRGGGYGGDRGGY 483
Score = 45.4 bits (106), Expect = 7e-05
Identities = 39/90 (43%), Positives = 44/90 (48%), Gaps = 15/90 (16%)
Query: 268 NSTPGGGS--GMGGSGMGGY-GRDGMD-NQGGYG---SVGRMGMGNNYSGGYGTPDGLGG 320
+S P GG G G G GY GR G ++GGYG S G G + GGY GG
Sbjct: 383 DSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGG 442
Query: 321 YG--RGGGG----SGGYYGQGGMSGGGWRG 344
YG R GGG GG G GG GGG+ G
Sbjct: 443 YGGDRSGGGYGGDRGG--GYGGDRGGGYGG 470
Score = 39.7 bits (91), Expect = 0.004
Identities = 36/97 (37%), Positives = 37/97 (38%), Gaps = 19/97 (19%)
Query: 97 KGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGRGSMYDRMRRGGDGY----DGGYGGFDD 152
+G Y R G G Y G RGGY G Y R GG GY GGYGG
Sbjct: 495 RGGYGGDRGGYGGDRGGYG---GDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRS 551
Query: 153 ---YGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGD 186
YGG GYG D RG G GG D
Sbjct: 552 GGGYGGDRGGGYGGD---------RGGYGGKMGGRND 579
Score = 36.2 bits (82), Expect = 0.044
Identities = 48/212 (22%), Positives = 73/212 (34%), Gaps = 42/212 (19%)
Query: 112 GPYDRPIGGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDD--YGGYNNYGYGNDGFDDR 169
G + G G + G Y G Y YGG+++ Y+ Y N G
Sbjct: 29 GQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSYGGYENQKQSSYSQQPYNNQGQQQN 88
Query: 170 MRDGRGMGG---------HGYGGAGDASSGF--HGGHFVHMRGLPFRATENDIANFFSPL 218
M GG +G + D SG+ H G + ++ +N+
Sbjct: 89 MESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSY------------DEQSNYDQ-- 134
Query: 219 NPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMG 278
D + + + + E +H ++D RY E ++ GGS G
Sbjct: 135 -----QHDSYSQNQQSYHSQRENYSHH------TQDDRRDVSRYGE---DNRGYGGSQGG 180
Query: 279 GSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSG 310
G G GGY +DG G S G G N+ G
Sbjct: 181 GRGRGGYDKDGRGPMTG-SSGGDRGGFKNFGG 211
Score = 35.8 bits (81), Expect = 0.058
Identities = 31/85 (36%), Positives = 36/85 (42%), Gaps = 9/85 (10%)
Query: 97 KGFYDPPRRLLGQRPGPY--DRPIGGRGGYYGAGRGSMYDRMRR-GGDGYDGGYGGF--- 150
+G Y R G G Y DR GG GG G G G DR GGD GGYGG
Sbjct: 502 RGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGG 561
Query: 151 ---DDYGGYNNYGYGNDGFDDRMRD 172
D GGY G + + + R+
Sbjct: 562 GYGGDRGGYGGKMGGRNDYRNDQRN 586
Score = 28.9 bits (63), Expect = 7.1
Identities = 18/51 (35%), Positives = 20/51 (39%), Gaps = 5/51 (9%)
Query: 275 SGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSG----GYGTPDGLGGY 321
S G G GYG+ + GYG G NYSG G GGY
Sbjct: 18 STYGNPGSQGYGQ-ASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSYGGY 67
>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
Length = 592
Score = 70.9 bits (172), Expect = 2e-12
Identities = 84/312 (26%), Positives = 115/312 (36%), Gaps = 71/312 (22%)
Query: 70 AENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGR 129
++N H +R Y + R ++ + + R G + G GRGGY GR
Sbjct: 143 SQNQQSYHSQR--ENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGR-----GRGGYDKDGR 195
Query: 130 GSMYDRMRRGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASS 189
G M G G G GGF ++GG+ +YG D D+ S
Sbjct: 196 GPM-----TGSSG--GDRGGFKNFGGHRDYGPRTD--------------------ADSES 228
Query: 190 GFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGA----------DGRATGEADV 239
+ + ++GL + + + FF + I+ + G G+ GEA V
Sbjct: 229 DNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATV 288
Query: 240 EFVTHEDAVAAMS-KDKNNMQHRYIEL-FLNSTP----GGGSGMGGSGMGGY-GRDGMDN 292
F A AA+ D I++ F P GGGSG G G GGY GR G
Sbjct: 289 SFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQG 348
Query: 293 QGG----------YGSVGRMGMGNNYSGGY--------GTPDGLGGYGRGGGGSGGYYGQ 334
+GG S G M S P G GRG GG GY G+
Sbjct: 349 RGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGR 408
Query: 335 GGMSG--GGWRG 344
GG G GG+ G
Sbjct: 409 GGRGGDRGGYGG 420
Score = 70.1 bits (170), Expect = 3e-12
Identities = 114/397 (28%), Positives = 141/397 (35%), Gaps = 113/397 (28%)
Query: 11 NDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNG-------ITLTMDYQ-GRSTGEAFV 62
+++ + T+ ++GL G S +++ +FF+ + I+ I L D G+ GEA V
Sbjct: 229 DNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATV 288
Query: 63 QFASKEIAENALG--KHKERIGHRYIEIFRSSRSEI------------KGFY-------- 100
F A+ A+ KE G+ F + R E +G Y
Sbjct: 289 SFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQG 348
Query: 101 ---DP-------PRRLLGQ-------------RPGPYD-RPIGG--RGGYYGAGRGSMYD 134
DP P G P P D RP GG RG YG RG
Sbjct: 349 RGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGY--- 405
Query: 135 RMRRGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGG--AGDASSGFH 192
R R G G GGYGG D GG GYG D G GG GYGG +G G
Sbjct: 406 RGRGGRGGDRGGYGG-DRSGG----GYGGDRSSGGGYSGDRSGG-GYGGDRSGGGYGGDR 459
Query: 193 GGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMS 252
GG + RG + G D G D
Sbjct: 460 GGGYGGDRGGGYGGDRGG---------------GYGGDRGGYGG---------DRGGGYG 495
Query: 253 KDKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRD-----GMDNQGGYGSV--GRMGMG 305
D+ GG G G GGYG D G ++GGYG G G G
Sbjct: 496 GDRGGY-------------GGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYG 542
Query: 306 NNYSGGYGTPDGLGGYG--RGGGGSGGYYGQGGMSGG 340
+ SGGYG GGYG RGGG G G GG GG
Sbjct: 543 GDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGG 579
Score = 59.7 bits (143), Expect = 4e-09
Identities = 72/225 (32%), Positives = 81/225 (36%), Gaps = 47/225 (20%)
Query: 116 RPIGGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGG-----YNNYGYGNDGFDDRM 170
R GG GY G G G DR GGD GGYGG GG + GYG D
Sbjct: 397 RGYGGERGYRGRG-GRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGD------ 449
Query: 171 RDGRGMGGH---GYGG-AGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHID 226
R G G GG GYGG G G GG + RG D + D
Sbjct: 450 RSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRG----GYGGDRGGGYGG--------D 497
Query: 227 IGADGRATGEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYG 286
G G G + + D++ + GGGSG GG GGYG
Sbjct: 498 RGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGY-------GGDRGGGSGYGGDRSGGYG 550
Query: 287 RDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGSGGY 331
D GG G G + GGYG GGYG GG Y
Sbjct: 551 GD---RSGG-------GYGGDRGGGYG--GDRGGYGGKMGGRNDY 583
Score = 52.8 bits (125), Expect = 5e-07
Identities = 34/74 (45%), Positives = 37/74 (50%), Gaps = 4/74 (5%)
Query: 274 GSGMGGSGMGGYGRDGMDNQGGYGSV-GRMGMGNNYSGGYGTPDGLGGYG--RGGGGSGG 330
G G GG G G G + GGYG G G + GGYG G GGYG RGGG G
Sbjct: 424 GGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRG-GGYGGDRGGGYGGD 482
Query: 331 YYGQGGMSGGGWRG 344
G GG GGG+ G
Sbjct: 483 RGGYGGDRGGGYGG 496
Score = 48.9 bits (115), Expect = 7e-06
Identities = 38/84 (45%), Positives = 39/84 (46%), Gaps = 15/84 (17%)
Query: 274 GSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSG-----GYGTPDGLGGYG--RGGG 326
G G G GGYG D + GGYG G G YSG GYG GGYG RGGG
Sbjct: 407 GRGGRGGDRGGYGGDR--SGGGYG--GDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGG 462
Query: 327 ----GSGGYYGQGGMSGGGWRGMY 346
GGY G G GG RG Y
Sbjct: 463 YGGDRGGGYGGDRGGGYGGDRGGY 486
Score = 45.4 bits (106), Expect = 7e-05
Identities = 39/90 (43%), Positives = 44/90 (48%), Gaps = 15/90 (16%)
Query: 268 NSTPGGGS--GMGGSGMGGY-GRDGMD-NQGGYG---SVGRMGMGNNYSGGYGTPDGLGG 320
+S P GG G G G GY GR G ++GGYG S G G + GGY GG
Sbjct: 386 DSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGG 445
Query: 321 YG--RGGGG----SGGYYGQGGMSGGGWRG 344
YG R GGG GG G GG GGG+ G
Sbjct: 446 YGGDRSGGGYGGDRGG--GYGGDRGGGYGG 473
Score = 39.7 bits (91), Expect = 0.004
Identities = 36/97 (37%), Positives = 37/97 (38%), Gaps = 19/97 (19%)
Query: 97 KGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGRGSMYDRMRRGGDGY----DGGYGGFDD 152
+G Y R G G Y G RGGY G Y R GG GY GGYGG
Sbjct: 498 RGGYGGDRGGYGGDRGGYG---GDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRS 554
Query: 153 ---YGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGD 186
YGG GYG D RG G GG D
Sbjct: 555 GGGYGGDRGGGYGGD---------RGGYGGKMGGRND 582
Score = 35.8 bits (81), Expect = 0.058
Identities = 31/85 (36%), Positives = 36/85 (42%), Gaps = 9/85 (10%)
Query: 97 KGFYDPPRRLLGQRPGPY--DRPIGGRGGYYGAGRGSMYDRMRR-GGDGYDGGYGGF--- 150
+G Y R G G Y DR GG GG G G G DR GGD GGYGG
Sbjct: 505 RGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGG 564
Query: 151 ---DDYGGYNNYGYGNDGFDDRMRD 172
D GGY G + + + R+
Sbjct: 565 GYGGDRGGYGGKMGGRNDYRNDQRN 589
Score = 31.6 bits (70), Expect = 1.1
Identities = 18/53 (33%), Positives = 21/53 (39%), Gaps = 1/53 (1%)
Query: 275 SGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGG 327
S G G GYG+ + GYG G NYSG GY + GG
Sbjct: 18 STYGNPGSQGYGQ-ASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYSQSYGG 69
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 63.2 bits (152), Expect = 3e-10
Identities = 39/80 (48%), Positives = 42/80 (52%), Gaps = 5/80 (6%)
Query: 272 GGGSGMGGSGMGGYGR-DGMDNQGGYGSVGRMGMGNNYSGGYGTPDGL-GGYGRGG---G 326
GGGSG GG GGYG G + GG G G G NY GG G+ G GGYG G G
Sbjct: 521 GGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRG 580
Query: 327 GSGGYYGQGGMSGGGWRGMY 346
GSGG +G G GG G Y
Sbjct: 581 GSGGSHGGGSGFGGESGGSY 600
Score = 61.2 bits (147), Expect = 1e-09
Identities = 38/85 (44%), Positives = 41/85 (48%), Gaps = 2/85 (2%)
Query: 263 IELFLNSTPGGGSGMGGSGMGGYGRDGMDNQGG-YGSVGRMGMGNNYSGGYGTPDGLGGY 321
IE + N GG SG G G G GG YG R G G +Y GG G+ G GG
Sbjct: 451 IETYHNLLEGGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGG-GSGGGYGGG 509
Query: 322 GRGGGGSGGYYGQGGMSGGGWRGMY 346
GGSGG YG G SGGG G Y
Sbjct: 510 SGSRGGSGGSYGGGSGSGGGSGGGY 534
Score = 60.1 bits (144), Expect = 3e-09
Identities = 38/76 (50%), Positives = 38/76 (50%), Gaps = 3/76 (3%)
Query: 272 GGGSGMG-GSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGSGG 330
GGGSG G G G G G G GG GS G G G Y GG G G G GGSGG
Sbjct: 499 GGGSGGGYGGGSGSRGGSGGSYGGGSGSGG--GSGGGYGGGSGGGHSGGSGGGHSGGSGG 556
Query: 331 YYGQGGMSGGGWRGMY 346
YG G SGGG G Y
Sbjct: 557 NYGGGSGSGGGSGGGY 572
Score = 59.7 bits (143), Expect = 4e-09
Identities = 32/72 (44%), Positives = 40/72 (55%), Gaps = 4/72 (5%)
Query: 266 FLNSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGG 325
F S+ GGG G G G GG G + GG+G G G + GGYG+ G GG+G G
Sbjct: 81 FSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGS--GFGGFGGFG 138
Query: 326 GGSGGYYGQGGM 337
GG+GG G GG+
Sbjct: 139 GGAGG--GDGGI 148
Score = 58.5 bits (140), Expect = 8e-09
Identities = 40/76 (52%), Positives = 41/76 (53%), Gaps = 9/76 (11%)
Query: 273 GGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGG-YGRG---GGGS 328
G G GGSG G YGR GG S G G G Y GG G+ G GG YG G GGGS
Sbjct: 474 GLGGRGGSG-GSYGRGSRGGSGG--SYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGS 530
Query: 329 GGYYGQGGMSGGGWRG 344
GG G GG SGGG G
Sbjct: 531 GG--GYGGGSGGGHSG 544
Score = 53.9 bits (128), Expect = 2e-07
Identities = 35/77 (45%), Positives = 40/77 (51%), Gaps = 13/77 (16%)
Query: 272 GGGSGMGGSGMGGYGR---DGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGS 328
GGGSG G G YG G + GGYG G G +SGG G GG+ G GG+
Sbjct: 507 GGGSGSRGGSGGSYGGGSGSGGGSGGGYGG----GSGGGHSGGSG-----GGHSGGSGGN 557
Query: 329 -GGYYGQGGMSGGGWRG 344
GG G GG SGGG+ G
Sbjct: 558 YGGGSGSGGGSGGGYGG 574
Score = 53.9 bits (128), Expect = 2e-07
Identities = 37/81 (45%), Positives = 39/81 (48%), Gaps = 7/81 (8%)
Query: 269 STPGGGSGMG---GSGMGGYGRDGMDNQGGYGS--VGRMGMGNNYSGGYGTPDGLGGYGR 323
S GGGSG G GSG G G G + GG G G G G GGYG G G G
Sbjct: 524 SGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYG--GGSGSRGG 581
Query: 324 GGGGSGGYYGQGGMSGGGWRG 344
GG GG G GG SGG + G
Sbjct: 582 SGGSHGGGSGFGGESGGSYGG 602
Score = 53.1 bits (126), Expect = 4e-07
Identities = 36/77 (46%), Positives = 39/77 (50%), Gaps = 10/77 (12%)
Query: 272 GGGSGMG------GSGMGGYGRD-GMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRG 324
GGGSG G G G GG R G + GGY S G G G + GG G G GGYG G
Sbjct: 74 GGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSG--GFGGGFGGGSGGGFG-GGYGSG 130
Query: 325 GGGSGGYYGQGGMSGGG 341
GG GG+ G G GG
Sbjct: 131 FGGFGGFGGGAGGGDGG 147
Score = 50.4 bits (119), Expect = 2e-06
Identities = 32/71 (45%), Positives = 35/71 (49%), Gaps = 8/71 (11%)
Query: 272 GGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGSGGY 331
GGG G GGS Y R + GG G GR + Y GG GRGGGGS GY
Sbjct: 19 GGGLGSGGSIRSSYSR--FSSSGGGGGGGRFSSSSGYGGGSSRV-----CGRGGGGSFGY 71
Query: 332 YGQGGMSGGGW 342
GG SGGG+
Sbjct: 72 -SYGGGSGGGF 81
Score = 50.1 bits (118), Expect = 3e-06
Identities = 33/82 (40%), Positives = 36/82 (43%), Gaps = 10/82 (12%)
Query: 273 GGSGMGGSGMGGYGRDG---MDNQGGYGSVGRMGMGNNYSGGYGTPDGLG-----GYGRG 324
GG G GG G GG R + GG G GR + Y GG G G GY G
Sbjct: 15 GGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYG 74
Query: 325 GGGSGGYYGQ--GGMSGGGWRG 344
GG GG+ GG GGG RG
Sbjct: 75 GGSGGGFSASSLGGGFGGGSRG 96
Score = 50.1 bits (118), Expect = 3e-06
Identities = 38/84 (45%), Positives = 41/84 (48%), Gaps = 17/84 (20%)
Query: 268 NSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGG 327
+S GG GGSG G YG GG GS G G G Y GG G+ G GG GG G
Sbjct: 542 HSGGSGGGHSGGSG-GNYG-------GGSGSGG--GSGGGYGGGSGSRGGSGGSHGGGSG 591
Query: 328 ----SGGYYGQG---GMSGGGWRG 344
SGG YG G SGGG+ G
Sbjct: 592 FGGESGGSYGGGEEASGSGGGYGG 615
Score = 49.3 bits (116), Expect = 5e-06
Identities = 31/76 (40%), Positives = 37/76 (48%), Gaps = 7/76 (9%)
Query: 272 GGGS---GMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGS 328
GGGS GG GG+ + GG+G G G G GGY + G GG G GGG
Sbjct: 65 GGGSFGYSYGGGSGGGFSASSLG--GGFGG-GSRGFGGASGGGYSSSGGFGG-GFGGGSG 120
Query: 329 GGYYGQGGMSGGGWRG 344
GG+ G G GG+ G
Sbjct: 121 GGFGGGYGSGFGGFGG 136
Score = 49.3 bits (116), Expect = 5e-06
Identities = 31/77 (40%), Positives = 32/77 (41%), Gaps = 7/77 (9%)
Query: 118 IGGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMG 177
+GGRGG G Y R RGG G G YGG GGY G G G G
Sbjct: 475 LGGRGG-----SGGSYGRGSRGGSG--GSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSG 527
Query: 178 GHGYGGAGDASSGFHGG 194
G GG G S G H G
Sbjct: 528 GGSGGGYGGGSGGGHSG 544
Score = 48.9 bits (115), Expect = 7e-06
Identities = 33/69 (47%), Positives = 35/69 (50%), Gaps = 10/69 (14%)
Query: 272 GGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGG-YGRGGGGSGG 330
GGGSG GG GGYG GG GS G G G ++ GG G GG YG G SG
Sbjct: 559 GGGSGSGGGSGGGYG-------GGSGSRG--GSGGSHGGGSGFGGESGGSYGGGEEASGS 609
Query: 331 YYGQGGMSG 339
G GG SG
Sbjct: 610 GGGYGGGSG 618
Score = 48.5 bits (114), Expect = 9e-06
Identities = 32/78 (41%), Positives = 36/78 (46%), Gaps = 19/78 (24%)
Query: 119 GGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGG 178
GG GG YG G GS RGG G G YGG GG + GYG G GG
Sbjct: 500 GGSGGGYGGGSGS------RGGSG--GSYGGGSGSGGGSGGGYGG-----------GSGG 540
Query: 179 HGYGGAGDASSGFHGGHF 196
GG+G SG GG++
Sbjct: 541 GHSGGSGGGHSGGSGGNY 558
Score = 48.1 bits (113), Expect = 1e-05
Identities = 34/84 (40%), Positives = 40/84 (47%), Gaps = 10/84 (11%)
Query: 269 STPGGGSGMG----GSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRG 324
S+ GGG G G SG GG G + +GG GS G G GG+ GG+G G
Sbjct: 36 SSSGGGGGGGRFSSSSGYGG-GSSRVCGRGGGGSFG-YSYGGGSGGGFSASSLGGGFGGG 93
Query: 325 ----GGGSGGYYGQGGMSGGGWRG 344
GG SGG Y G GGG+ G
Sbjct: 94 SRGFGGASGGGYSSSGGFGGGFGG 117
Score = 47.0 bits (110), Expect = 3e-05
Identities = 31/86 (36%), Positives = 37/86 (43%), Gaps = 9/86 (10%)
Query: 119 GGRGGYYGAGRGSMYDRMRRGG--DGYDGGYGGFDDYGGYNNYGYGNDGFDDRMRDGRGM 176
GG GG YG G G + GG G G YGG GG + GYG G
Sbjct: 528 GGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHG 587
Query: 177 GGHGYG-------GAGDASSGFHGGH 195
GG G+G G G+ +SG GG+
Sbjct: 588 GGSGFGGESGGSYGGGEEASGSGGGY 613
Score = 45.8 bits (107), Expect = 6e-05
Identities = 31/82 (37%), Positives = 34/82 (41%), Gaps = 14/82 (17%)
Query: 119 GGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNNYGYGNDG-----FDDRMRDG 173
GG GG YG G GS G G GGYGG G G G+ G + G
Sbjct: 514 GGSGGSYGGGSGS--------GGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSG 565
Query: 174 RGMGGHGYGGAGDASSGFHGGH 195
G GG GYGG + G G H
Sbjct: 566 GGSGG-GYGGGSGSRGGSGGSH 586
Score = 42.0 bits (97), Expect = 8e-04
Identities = 27/61 (44%), Positives = 29/61 (47%), Gaps = 3/61 (4%)
Query: 269 STPGGGSGMG-GSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGG 327
S GGGSG G G G G G G + GG G G G +Y GG GGYG G G
Sbjct: 562 SGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGE--SGGSYGGGEEASGSGGGYGGGSGK 619
Query: 328 S 328
S
Sbjct: 620 S 620
Score = 41.6 bits (96), Expect = 0.001
Identities = 31/83 (37%), Positives = 37/83 (44%), Gaps = 8/83 (9%)
Query: 119 GGRGGY-YGAGRGSMYDRMRRGGDGYDGGYGGFDDY--GGYNNYGYGNDGFDDR----MR 171
GG GY YG G G + GG G+ GG GF GGY++ G GF
Sbjct: 66 GGSFGYSYGGGSGGGFSASSLGG-GFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFG 124
Query: 172 DGRGMGGHGYGGAGDASSGFHGG 194
G G G G+GG G + G GG
Sbjct: 125 GGYGSGFGGFGGFGGGAGGGDGG 147
Score = 39.7 bits (91), Expect = 0.004
Identities = 28/71 (39%), Positives = 32/71 (45%), Gaps = 15/71 (21%)
Query: 119 GGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGG 178
GG GG YG G GS RGG G +GG +GG + YG + G GG
Sbjct: 566 GGSGGGYGGGSGS------RGGSGG--SHGGGSGFGGESGGSYGGG------EEASGSGG 611
Query: 179 HGYGGAGDASS 189
GYGG SS
Sbjct: 612 -GYGGGSGKSS 621
Score = 39.3 bits (90), Expect = 0.005
Identities = 37/100 (37%), Positives = 41/100 (41%), Gaps = 22/100 (22%)
Query: 119 GGRGGYYGAGRG--SMYDRMRRGGDGYDG-------GYGGFDDY------GGYNNYGYG- 162
GG GG G+G S Y R G G G GYGG GG Y YG
Sbjct: 16 GGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGG 75
Query: 163 --NDGFD-DRMRDGRGMGGHGYGGA---GDASSGFHGGHF 196
GF + G G G G+GGA G +SSG GG F
Sbjct: 76 GSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGF 115
Score = 38.9 bits (89), Expect = 0.007
Identities = 29/80 (36%), Positives = 34/80 (42%), Gaps = 6/80 (7%)
Query: 119 GGRGGYY----GAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDRMRDGR 174
GG GG + G G GS R GG + YGG GG++ G GF R
Sbjct: 41 GGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSG-GGFSASSLGG-GFGGGSRGFG 98
Query: 175 GMGGHGYGGAGDASSGFHGG 194
G G GY +G GF GG
Sbjct: 99 GASGGGYSSSGGFGGGFGGG 118
Score = 36.6 bits (83), Expect = 0.034
Identities = 24/71 (33%), Positives = 30/71 (42%), Gaps = 6/71 (8%)
Query: 92 SRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFD 151
S S + G + R G G GG GG +G G G + G GY G+GGF
Sbjct: 82 SASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGF------GGGYGSGFGGFG 135
Query: 152 DYGGYNNYGYG 162
+GG G G
Sbjct: 136 GFGGGAGGGDG 146
>gi|109255251 loricrin [Homo sapiens]
Length = 312
Score = 62.4 bits (150), Expect = 6e-10
Identities = 38/72 (52%), Positives = 39/72 (54%), Gaps = 5/72 (6%)
Query: 270 TPGGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYG-TPDGLGGYGRGGGGS 328
T GGG G GGSG GG G G GG G G G YSGG G + G GG GGGG
Sbjct: 19 TSGGGGGGGGSGGGGCGFFGGGGSGG----GSSGSGCGYSGGGGYSGGGCGGGSSGGGGG 74
Query: 329 GGYYGQGGMSGG 340
GG G GG SGG
Sbjct: 75 GGIGGCGGGSGG 86
Score = 53.9 bits (128), Expect = 2e-07
Identities = 36/70 (51%), Positives = 39/70 (55%), Gaps = 8/70 (11%)
Query: 272 GGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGSGGY 331
GGGSG GGS G G G GG S G G G++ GG G G+GG G G GGS Y
Sbjct: 39 GGGSG-GGSSGSGCGYSG----GGGYSGGGCGGGSSGGGGGG---GIGGCGGGSGGSVKY 90
Query: 332 YGQGGMSGGG 341
G GG SGGG
Sbjct: 91 SGGGGSSGGG 100
Score = 53.9 bits (128), Expect = 2e-07
Identities = 35/82 (42%), Positives = 41/82 (50%), Gaps = 9/82 (10%)
Query: 274 GSGMGGSGMGGYGRDGM----DNQGGYGSVGRMGMGN----NYSGGYGTPDGLGG-YGRG 324
GSG G SG GGY G GG G +G G G+ YSGG G+ G G + G
Sbjct: 48 GSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSG 107
Query: 325 GGGSGGYYGQGGMSGGGWRGMY 346
GGGSG + GG S GG G +
Sbjct: 108 GGGSGCFSSGGGGSSGGGSGCF 129
Score = 53.1 bits (126), Expect = 4e-07
Identities = 64/223 (28%), Positives = 75/223 (33%), Gaps = 52/223 (23%)
Query: 120 GRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGH 179
G GG G G G GG GG G F GG G+ + G GG
Sbjct: 117 GGGGSSGGGSGCFSSG---GGGSSGGGSGCFSSGGG----GFSGQAVQCQSYGGVSSGGS 169
Query: 180 GYGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADV 239
GG+G SSG GG G G G ++G +
Sbjct: 170 SGGGSGCFSSGGGGGSVCGYSGG-----------------------GSGCGGGSSGGSGS 206
Query: 240 EFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSV 299
+V+ + + P G G SG GG G G + GG G
Sbjct: 207 GYVSSQQVTQT-----------------SCAPQPSYGGGSSGGGGSGGSGCFSSGGGG-- 247
Query: 300 GRMGMGNNYSG-GYGTPDGLGGYGRGGGGSGGYYGQGGMSGGG 341
G G G SG G G GG GGG SGG G GG S GG
Sbjct: 248 GSSGCGGGSSGIGSGCIISGGGSVCGGGSSGG--GGGGSSVGG 288
Score = 52.0 bits (123), Expect = 8e-07
Identities = 64/235 (27%), Positives = 74/235 (31%), Gaps = 61/235 (25%)
Query: 119 GGRGGYYGAGRGSMYDRMRRGGDGYDGGYGG----FDDYGGYNNYGYGNDGFDDRMRDGR 174
GG GG G G G GG G GG G + GGY+ G G
Sbjct: 24 GGGGGSGGGGCGFF------GGGGSGGGSSGSGCGYSGGGGYSGGGCGGG-------SSG 70
Query: 175 GMGGHGYGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRAT 234
G GG G GG G S G + G ++
Sbjct: 71 GGGGGGIGGCGGGSGG---------------------------------SVKYSGGGGSS 97
Query: 235 GEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDGMDNQG 294
G F + S F S+ GGGS GGSG G G Q
Sbjct: 98 GGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCF--SSGGGGSSGGGSGCFSSGGGGFSGQA 155
Query: 295 ----GYGSVGRMGMGNNYSGGYGTPDGLG---GYGRGGGGSGGYYGQGGMSGGGW 342
YG V G SG + + G G GY GG G GG G G SG G+
Sbjct: 156 VQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGG--GSSGGSGSGY 208
Score = 50.1 bits (118), Expect = 3e-06
Identities = 34/84 (40%), Positives = 37/84 (44%), Gaps = 9/84 (10%)
Query: 272 GGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDG---------LGGYG 322
GGG G G SG GG G G G GSV G G + GG G GG G
Sbjct: 61 GGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGG 120
Query: 323 RGGGGSGGYYGQGGMSGGGWRGMY 346
GGGSG + GG S GG G +
Sbjct: 121 SSGGGSGCFSSGGGGSSGGGSGCF 144
Score = 46.6 bits (109), Expect = 3e-05
Identities = 67/255 (26%), Positives = 79/255 (30%), Gaps = 72/255 (28%)
Query: 119 GGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGG-----YNNYGYGNDGFDDRMRDG 173
GG GG G G GS GG G GG G GG +++ G G+ G
Sbjct: 72 GGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSS 131
Query: 174 RGMGGHGYG-GAGDASSGFHGGHFVHMR---GLPFRATENDIANFFSPLNPIRVHIDIGA 229
G G G G G + G G V + G+ + + FS G
Sbjct: 132 GGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFS---------SGGG 182
Query: 230 DGRATGEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDG 289
G G + GGGSG GG GG G
Sbjct: 183 GGSVCGYS----------------------------------GGGSGCGGGSSGGSGSGY 208
Query: 290 MDNQ---------------GGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGG-----GSG 329
+ +Q G G G G G SGG G G GG G G G
Sbjct: 209 VSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGG 268
Query: 330 GYYGQGGMSGGGWRG 344
G GG SGGG G
Sbjct: 269 GSVCGGGSSGGGGGG 283
Score = 45.1 bits (105), Expect = 1e-04
Identities = 40/104 (38%), Positives = 46/104 (44%), Gaps = 27/104 (25%)
Query: 268 NSTPGGGSGMGGSGMGG-----YGRDGMDNQGGYG--SVGRMGMGNNYSGGYGTPDG--- 317
+S GGG G+GG G G Y G + GG G S G G G SGG G+ G
Sbjct: 68 SSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSG 127
Query: 318 ---LGGYGRGGGGS-------GGYYGQ-------GGMSGGGWRG 344
GG G GGGS GG+ GQ GG+S GG G
Sbjct: 128 CFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSG 171
>gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo
sapiens]
Length = 898
Score = 62.0 bits (149), Expect = 8e-10
Identities = 75/255 (29%), Positives = 98/255 (38%), Gaps = 53/255 (20%)
Query: 102 PPRRLLGQRPGPYDRPIGGRGGYYGAGRGSMYDRMRRGGDGYDG-GYGGFDDYGGYNNYG 160
PP L G+ G R G G+ GA G + G GY GYGG GY+ +
Sbjct: 639 PPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMN----AGAGYGSYGYGGNSATAGYSQF- 693
Query: 161 YGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNP 220
Y N G G GG G GG G SSG+ G ++ + D N+ SP+ P
Sbjct: 694 YSNGG-----HSGNASGGGGGGGGG--SSGY-GSYY-----------QGD--NYNSPVPP 732
Query: 221 IRVHIDIGADGRATGEADVEFVTHEDAVAAMS--------------KDKNNMQHRYIELF 266
G+ + +H+ + + K N+ Q Y
Sbjct: 733 KHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSN 792
Query: 267 LNSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGT--PDGLGGYGRG 324
++PGGG G Y + N G G GR G GN+Y G + P GGYG G
Sbjct: 793 SYNSPGGGGG------SDYNYESKFNYSGSG--GRSG-GNSYGSGGASYNPGSHGGYGGG 843
Query: 325 GGGSGGYYG-QGGMS 338
GG Y G QGG S
Sbjct: 844 SGGGSSYQGKQGGYS 858
Score = 50.1 bits (118), Expect = 3e-06
Identities = 62/241 (25%), Positives = 84/241 (34%), Gaps = 53/241 (21%)
Query: 112 GPYDRPIGGRGGYYGAGRGSMYDRMRRGGDGYDGG-YGGFDDYG-GYNNYGYGNDGFDDR 169
GP + G GRG R R G G+ G +GG+ + G GY +YGYG +
Sbjct: 631 GPMHNEVPPPPNLRGRGRGGSI-RGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAG 689
Query: 170 MRDGRGMGGH------GYGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRV 223
GGH G GG G SSG+ G ++ + D N+ SP+ P
Sbjct: 690 YSQFYSNGGHSGNASGGGGGGGGGSSGY-GSYY-----------QGD--NYNSPVPP--- 732
Query: 224 HIDIGADGRATGEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSGMG 283
+ G+ + + + + Q Y N +P G
Sbjct: 733 --------KHAGKKQPHGGQQKPSYGSGYQSHQGQQQSY-----NQSPYSNYGPPQGKQK 779
Query: 284 GYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGSGGYYGQGGMSGGGWR 343
GY QG Y +YS Y +P G GG Y G GG SGG
Sbjct: 780 GYNH----GQGSY----------SYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSY 825
Query: 344 G 344
G
Sbjct: 826 G 826
Score = 28.9 bits (63), Expect = 7.1
Identities = 21/74 (28%), Positives = 28/74 (37%), Gaps = 11/74 (14%)
Query: 279 GSGMGGYGRD------GMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGSGGYY 332
G GMGG + + +G GS+ G G + G GGY G G G Y
Sbjct: 626 GFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGA-----NHGGYMNAGAGYGSYG 680
Query: 333 GQGGMSGGGWRGMY 346
G + G+ Y
Sbjct: 681 YGGNSATAGYSQFY 694
>gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo
sapiens]
Length = 894
Score = 62.0 bits (149), Expect = 8e-10
Identities = 75/255 (29%), Positives = 98/255 (38%), Gaps = 53/255 (20%)
Query: 102 PPRRLLGQRPGPYDRPIGGRGGYYGAGRGSMYDRMRRGGDGYDG-GYGGFDDYGGYNNYG 160
PP L G+ G R G G+ GA G + G GY GYGG GY+ +
Sbjct: 635 PPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMN----AGAGYGSYGYGGNSATAGYSQF- 689
Query: 161 YGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNP 220
Y N G G GG G GG G SSG+ G ++ + D N+ SP+ P
Sbjct: 690 YSNGG-----HSGNASGGGGGGGGG--SSGY-GSYY-----------QGD--NYNSPVPP 728
Query: 221 IRVHIDIGADGRATGEADVEFVTHEDAVAAMS--------------KDKNNMQHRYIELF 266
G+ + +H+ + + K N+ Q Y
Sbjct: 729 KHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSN 788
Query: 267 LNSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGT--PDGLGGYGRG 324
++PGGG G Y + N G G GR G GN+Y G + P GGYG G
Sbjct: 789 SYNSPGGGGG------SDYNYESKFNYSGSG--GRSG-GNSYGSGGASYNPGSHGGYGGG 839
Query: 325 GGGSGGYYG-QGGMS 338
GG Y G QGG S
Sbjct: 840 SGGGSSYQGKQGGYS 854
Score = 50.1 bits (118), Expect = 3e-06
Identities = 62/241 (25%), Positives = 84/241 (34%), Gaps = 53/241 (21%)
Query: 112 GPYDRPIGGRGGYYGAGRGSMYDRMRRGGDGYDGG-YGGFDDYG-GYNNYGYGNDGFDDR 169
GP + G GRG R R G G+ G +GG+ + G GY +YGYG +
Sbjct: 627 GPMHNEVPPPPNLRGRGRGGSI-RGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAG 685
Query: 170 MRDGRGMGGH------GYGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRV 223
GGH G GG G SSG+ G ++ + D N+ SP+ P
Sbjct: 686 YSQFYSNGGHSGNASGGGGGGGGGSSGY-GSYY-----------QGD--NYNSPVPP--- 728
Query: 224 HIDIGADGRATGEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSGMG 283
+ G+ + + + + Q Y N +P G
Sbjct: 729 --------KHAGKKQPHGGQQKPSYGSGYQSHQGQQQSY-----NQSPYSNYGPPQGKQK 775
Query: 284 GYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGSGGYYGQGGMSGGGWR 343
GY QG Y +YS Y +P G GG Y G GG SGG
Sbjct: 776 GYNH----GQGSY----------SYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSY 821
Query: 344 G 344
G
Sbjct: 822 G 822
Score = 28.9 bits (63), Expect = 7.1
Identities = 21/74 (28%), Positives = 28/74 (37%), Gaps = 11/74 (14%)
Query: 279 GSGMGGYGRD------GMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGSGGYY 332
G GMGG + + +G GS+ G G + G GGY G G G Y
Sbjct: 622 GFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGA-----NHGGYMNAGAGYGSYG 676
Query: 333 GQGGMSGGGWRGMY 346
G + G+ Y
Sbjct: 677 YGGNSATAGYSQFY 690
>gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapiens]
Length = 1270
Score = 61.6 bits (148), Expect = 1e-09
Identities = 38/87 (43%), Positives = 41/87 (47%), Gaps = 12/87 (13%)
Query: 272 GGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLG--GYGRGG---- 325
G G GGS G G G + GGYGS G G N++ GYG G G G RGG
Sbjct: 1170 GSGYRRGGSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGGFRGN 1229
Query: 326 ------GGSGGYYGQGGMSGGGWRGMY 346
G SGGY G GG GG RG Y
Sbjct: 1230 SGGDYRGPSGGYRGSGGFQRGGGRGAY 1256
Score = 53.9 bits (128), Expect = 2e-07
Identities = 34/84 (40%), Positives = 38/84 (45%), Gaps = 15/84 (17%)
Query: 272 GGGSGMGGSGMGGYGRDGMDNQGGYGS--------VGRMGMGNNYSGGYGTPDG----LG 319
GGG GG G GGYG + GYG+ V R G N G Y P G G
Sbjct: 1186 GGGYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSG 1245
Query: 320 GYGRGGGGSG---GYYGQGGMSGG 340
G+ RGGG GY+GQG GG
Sbjct: 1246 GFQRGGGRGAYGTGYFGQGRGGGG 1269
Score = 46.6 bits (109), Expect = 3e-05
Identities = 49/149 (32%), Positives = 60/149 (40%), Gaps = 18/149 (12%)
Query: 55 RSTGEAFVQFASKEIAE-NALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGP 113
R+ EA V +K+ A + L ER+ + +I R S + I R G RP
Sbjct: 1104 RAAMEALVVEVTKQPAIISQLDPVNERMLNMIRQISRPSAAGINLMIGSTRYGDGPRPPK 1163
Query: 114 YDRPIGGRGGYYGAGRGSMYDRMRRGGDGYDGG-YGGFDDYGGYNNYGYGNDGFDDRMRD 172
R G G RRGG Y GG YGG GGY + GYG R
Sbjct: 1164 MARYDNGSG-------------YRRGGSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGY 1210
Query: 173 GRGMGGHGYGGAGDASSGFHGGHFVHMRG 201
G G+GG GY G + GF G RG
Sbjct: 1211 GAGVGG-GYRGV--SRGGFRGNSGGDYRG 1236
Score = 40.0 bits (92), Expect = 0.003
Identities = 33/90 (36%), Positives = 39/90 (43%), Gaps = 16/90 (17%)
Query: 112 GPYDRPIGGRGGY----------YGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNNYGY 161
G Y G GGY YGAG G Y + RG G+ G GG DY G +
Sbjct: 1187 GGYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRG--GFRGNSGG--DYRGPSGGYR 1242
Query: 162 GNDGFDDRMRDGRGMGGHGYGGAGDASSGF 191
G+ GF + GRG G GY G G G+
Sbjct: 1243 GSGGF--QRGGGRGAYGTGYFGQGRGGGGY 1270
Score = 37.0 bits (84), Expect = 0.026
Identities = 42/133 (31%), Positives = 51/133 (38%), Gaps = 34/133 (25%)
Query: 232 RATGEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYG----- 286
RA EA V VT + A+ + N I + G + M GS G G
Sbjct: 1104 RAAMEALVVEVTKQPAIISQLDPVNERMLNMIRQISRPSAAGINLMIGSTRYGDGPRPPK 1163
Query: 287 RDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGSGGYYGQGGMS-------- 338
DN GY R G G++YSGG G GGG S G YG GG
Sbjct: 1164 MARYDNGSGY----RRG-GSSYSGG----------GYGGGYSSGGYGSGGYGGSANSFRA 1208
Query: 339 ------GGGWRGM 345
GGG+RG+
Sbjct: 1209 GYGAGVGGGYRGV 1221
Score = 29.3 bits (64), Expect = 5.4
Identities = 17/32 (53%), Positives = 17/32 (53%), Gaps = 1/32 (3%)
Query: 316 DGLGGYGRGGGG-SGGYYGQGGMSGGGWRGMY 346
D GY RGG SGG YG G SGG G Y
Sbjct: 1168 DNGSGYRRGGSSYSGGGYGGGYSSGGYGSGGY 1199
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 60.1 bits (144), Expect = 3e-09
Identities = 38/83 (45%), Positives = 42/83 (50%), Gaps = 8/83 (9%)
Query: 268 NSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGT-----PDGLGGYG 322
++T GG GG G GGYG G G GS G G G G YG+ G G YG
Sbjct: 509 HTTISGGGSRGGGG-GGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYG 567
Query: 323 RGGGGSG-GYYGQGGMSGGGWRG 344
GGGG G G YG G S GG+RG
Sbjct: 568 SGGGGGGHGSYGSGS-SSGGYRG 589
Score = 59.3 bits (142), Expect = 5e-09
Identities = 37/78 (47%), Positives = 39/78 (50%), Gaps = 9/78 (11%)
Query: 272 GGGS----GMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGY----GR 323
GGGS G GG G G YG G G GS G G G + G YG+ GGY G
Sbjct: 535 GGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGH-GSYGSGSSSGGYRGGSGG 593
Query: 324 GGGGSGGYYGQGGMSGGG 341
GGGGS G G GG S GG
Sbjct: 594 GGGGSSGGRGSGGGSSGG 611
Score = 58.2 bits (139), Expect = 1e-08
Identities = 35/81 (43%), Positives = 46/81 (56%), Gaps = 11/81 (13%)
Query: 269 STPGGGSGMGGSGMGGYGRDGMDNQGGYGSVGRM-----GMGNNYSGGYGTPDGLGGYGR 323
S+ GGG G G+G GG+G + N GG S+ G G+ + GGYG GG+G
Sbjct: 47 SSCGGGGGSFGAG-GGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGG----GGFGG 101
Query: 324 GGGGSGGYYGQGGMSGGGWRG 344
GG G GG +G GG+ GGG+ G
Sbjct: 102 GGFGGGG-FGGGGIGGGGFGG 121
Score = 56.6 bits (135), Expect = 3e-08
Identities = 36/94 (38%), Positives = 43/94 (45%), Gaps = 20/94 (21%)
Query: 119 GGRGGYYGAGRG-------------SMYDRMRRGG---DGYDGGYGGFDDYGGYNNYGYG 162
GG GG +GAG G S+ + RGG G+ GGYGG GG+ G+G
Sbjct: 50 GGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGG----GGFGGGGFG 105
Query: 163 NDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGHF 196
GF G G GG G GG G GF GG +
Sbjct: 106 GGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGY 139
Score = 55.1 bits (131), Expect = 9e-08
Identities = 36/81 (44%), Positives = 37/81 (45%), Gaps = 13/81 (16%)
Query: 272 GGGSGMG---------GSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDG--LGG 320
GGG G G GSG G YG G GG+GS G Y GG G G GG
Sbjct: 544 GGGGGRGSYGSGGSSYGSGGGSYGSGG--GGGGHGSYGSGSSSGGYRGGSGGGGGGSSGG 601
Query: 321 YGRGGGGSGGYYGQGGMSGGG 341
G GGG SGG G G S GG
Sbjct: 602 RGSGGGSSGGSIGGRGSSSGG 622
Score = 52.4 bits (124), Expect = 6e-07
Identities = 33/69 (47%), Positives = 35/69 (50%), Gaps = 8/69 (11%)
Query: 272 GGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGSGGY 331
GGG G GG G GG+G G G G +G G G SGG G GG G GGGG GG
Sbjct: 91 GGGYGGGGFGGGGFGGGGF----GGGGIGGGGFGGFGSGG----GGFGGGGFGGGGYGGG 142
Query: 332 YGQGGMSGG 340
YG GG
Sbjct: 143 YGPVCPPGG 151
Score = 52.4 bits (124), Expect = 6e-07
Identities = 34/78 (43%), Positives = 40/78 (51%), Gaps = 8/78 (10%)
Query: 119 GGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNNYG--YGNDGFDDRMRDGRGM 176
GG GG YG+G GS Y GG Y G GG G Y + G YG+ G G G
Sbjct: 519 GGGGGGYGSG-GSSYGS---GGGSYGSGGGGGGGRGSYGSGGSSYGSGG--GSYGSGGGG 572
Query: 177 GGHGYGGAGDASSGFHGG 194
GGHG G+G +S G+ GG
Sbjct: 573 GGHGSYGSGSSSGGYRGG 590
Score = 49.7 bits (117), Expect = 4e-06
Identities = 31/66 (46%), Positives = 36/66 (54%), Gaps = 7/66 (10%)
Query: 272 GGGSGMGGS-GMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGSGG 330
G GSG GG G GG+G G G G G G+G GG+G+ G GG+G GG G GG
Sbjct: 85 GRGSGFGGGYGGGGFGGGGF----GGGGFGGGGIGGGGFGGFGS--GGGGFGGGGFGGGG 138
Query: 331 YYGQGG 336
Y G G
Sbjct: 139 YGGGYG 144
Score = 43.9 bits (102), Expect = 2e-04
Identities = 28/76 (36%), Positives = 32/76 (42%), Gaps = 5/76 (6%)
Query: 120 GRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNNYG-YGNDGFDDRMRDGRGMGG 178
G GG G GRGS GG Y G G + GG +G YG+ R G G GG
Sbjct: 540 GSGGGGGGGRGSYGS----GGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGG 595
Query: 179 HGYGGAGDASSGFHGG 194
G G + G GG
Sbjct: 596 GGSSGGRGSGGGSSGG 611
Score = 43.5 bits (101), Expect = 3e-04
Identities = 32/75 (42%), Positives = 38/75 (50%), Gaps = 5/75 (6%)
Query: 272 GGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLG-GYGRGGG-GSG 329
GGG G S GG G G GG+GS + +G + S G G G G GGG G G
Sbjct: 40 GGGGGRFSSCGGGGGSFGAG--GGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGG 97
Query: 330 GYYGQGGMSGGGWRG 344
G +G GG GGG+ G
Sbjct: 98 G-FGGGGFGGGGFGG 111
Score = 42.7 bits (99), Expect = 5e-04
Identities = 30/79 (37%), Positives = 32/79 (40%), Gaps = 10/79 (12%)
Query: 119 GGRGGY------YGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGY-NNYGYGNDGFDDRMR 171
GGRG Y YG+G GS GG G G YG GGY G G G
Sbjct: 547 GGRGSYGSGGSSYGSGGGSYGS---GGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRG 603
Query: 172 DGRGMGGHGYGGAGDASSG 190
G G G GG G +S G
Sbjct: 604 SGGGSSGGSIGGRGSSSGG 622
Score = 39.7 bits (91), Expect = 0.004
Identities = 35/106 (33%), Positives = 39/106 (36%), Gaps = 3/106 (2%)
Query: 92 SRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFD 151
SR G Y G G Y GG GG G G G G GG GG
Sbjct: 517 SRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHG 576
Query: 152 DYG-GYNNYGY--GNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGG 194
YG G ++ GY G+ G GRG GG GG+ GG
Sbjct: 577 SYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGG 622
Score = 39.3 bits (90), Expect = 0.005
Identities = 23/58 (39%), Positives = 25/58 (43%)
Query: 138 RGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGH 195
RGG G G GG G +YG G G R G G +G GG S G GGH
Sbjct: 518 RGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGH 575
Score = 37.0 bits (84), Expect = 0.026
Identities = 27/74 (36%), Positives = 31/74 (41%), Gaps = 25/74 (33%)
Query: 121 RGGYYGAGRGSMYDRMRRGGDGYDGG-----------YGGFDDYGGYNNYGYGNDGFDDR 169
RGG G+G G Y GG G+ GG +GGF GG G+G GF
Sbjct: 82 RGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGG----GFGGGGF--- 134
Query: 170 MRDGRGMGGHGYGG 183
GG GYGG
Sbjct: 135 -------GGGGYGG 141
Score = 32.7 bits (73), Expect = 0.49
Identities = 21/48 (43%), Positives = 22/48 (45%), Gaps = 11/48 (22%)
Query: 309 SGGYGTPDGLGGYGRGGGG----------SGGYYGQGGMSGGGWRGMY 346
S + T G G G GGGG GG YG GG GGG RG Y
Sbjct: 506 STSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGG-GGGGGRGSY 552
Score = 32.0 bits (71), Expect = 0.84
Identities = 19/49 (38%), Positives = 22/49 (44%)
Query: 269 STPGGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDG 317
S G GGSG GG G G GG S G +G + SGG + G
Sbjct: 580 SGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGG 628
>gi|109452587 family with sequence similarity 98, member B isoform 1
[Homo sapiens]
Length = 433
Score = 60.1 bits (144), Expect = 3e-09
Identities = 34/68 (50%), Positives = 36/68 (52%), Gaps = 7/68 (10%)
Query: 272 GGGSGMGGSGMGGY------GRDGMDNQGGYGSVGRMGMGNNYSG-GYGTPDGLGGYGRG 324
GGG G GG G GG+ GR G +G YG G G Y G GYG P G GG G G
Sbjct: 363 GGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGG 422
Query: 325 GGGSGGYY 332
GGG GG Y
Sbjct: 423 GGGGGGGY 430
Score = 58.5 bits (140), Expect = 8e-09
Identities = 35/73 (47%), Positives = 37/73 (50%), Gaps = 11/73 (15%)
Query: 272 GGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSG-GYGTPDGLGGYGRGGGGSGG 330
GGG G G G GG GR G +G YG G G Y G GYG P G GGGG GG
Sbjct: 369 GGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYG------GGGGGGG 422
Query: 331 YYGQGGMSGGGWR 343
GG GGG+R
Sbjct: 423 ----GGGGGGGYR 431
Score = 57.4 bits (137), Expect = 2e-08
Identities = 37/78 (47%), Positives = 40/78 (51%), Gaps = 7/78 (8%)
Query: 272 GGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGSGGY 331
GGG G G G GG GR G GG G G G G + GG G G GG GGGG GG+
Sbjct: 332 GGGRGGWGGGGGGGGRGGGGGGGGRGGWG--GGGGGWGGGGGGGGGWGG--GGGGGRGGF 387
Query: 332 YGQG---GMSGGGWRGMY 346
G+G G G G RG Y
Sbjct: 388 QGRGDYGGRGGYGGRGGY 405
Score = 55.5 bits (132), Expect = 7e-08
Identities = 35/84 (41%), Positives = 38/84 (45%), Gaps = 10/84 (11%)
Query: 273 GGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGG------- 325
GG G GG G GG G GG G G G G + GG G G GG G GG
Sbjct: 331 GGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGR 390
Query: 326 ---GGSGGYYGQGGMSGGGWRGMY 346
GG GGY G+GG G G+ Y
Sbjct: 391 GDYGGRGGYGGRGGYGGRGYGDPY 414
Score = 54.7 bits (130), Expect = 1e-07
Identities = 39/80 (48%), Positives = 40/80 (50%), Gaps = 11/80 (13%)
Query: 272 GGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGY---GTPDGLGGY-GRGGGG 327
GGG G GG G GG G G GG G G G G GG+ G G GGY GRGG G
Sbjct: 351 GGGGGRGGWGGGGGGWGG----GGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYG 406
Query: 328 SGGY---YGQGGMSGGGWRG 344
GY YG GG GGG G
Sbjct: 407 GRGYGDPYGGGGGGGGGGGG 426
Score = 47.8 bits (112), Expect = 1e-05
Identities = 30/67 (44%), Positives = 32/67 (47%), Gaps = 7/67 (10%)
Query: 119 GGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGG 178
GG GG +G G G RGG G YGG YGG GYG G+ D G G GG
Sbjct: 370 GGGGGGWGGGGGG-----GRGGFQGRGDYGGRGGYGGRG--GYGGRGYGDPYGGGGGGGG 422
Query: 179 HGYGGAG 185
G GG G
Sbjct: 423 GGGGGGG 429
Score = 47.0 bits (110), Expect = 3e-05
Identities = 32/78 (41%), Positives = 37/78 (47%), Gaps = 9/78 (11%)
Query: 119 GGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGG 178
GG GG+ G G G GG G GG+ G DYGG YG G G+ GRG G
Sbjct: 361 GGGGGWGGGGGGG--GGWGGGGGGGRGGFQGRGDYGGRGGYG-GRGGYG-----GRGYGD 412
Query: 179 -HGYGGAGDASSGFHGGH 195
+G GG G G GG+
Sbjct: 413 PYGGGGGGGGGGGGGGGY 430
Score = 43.9 bits (102), Expect = 2e-04
Identities = 32/81 (39%), Positives = 35/81 (43%), Gaps = 7/81 (8%)
Query: 119 GGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDRMRDGR---- 174
GG GG G G G GG G+ GG GG +GG G G GF R G
Sbjct: 342 GGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGG--GGGRGGFQGRGDYGGRGGY 399
Query: 175 -GMGGHGYGGAGDASSGFHGG 194
G GG+G G GD G GG
Sbjct: 400 GGRGGYGGRGYGDPYGGGGGG 420
Score = 40.8 bits (94), Expect = 0.002
Identities = 30/83 (36%), Positives = 34/83 (40%), Gaps = 10/83 (12%)
Query: 111 PGPYDRPIGGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDRM 170
P P + P + G GRG GG G GG GG GG +G G G+
Sbjct: 317 PPPPEMPPWQKRQEGGGGRGGW------GGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGG 370
Query: 171 RDGRGMGGHGYGGAGDASSGFHG 193
G G GG G GG G GF G
Sbjct: 371 GGGGGWGGGGGGGRG----GFQG 389
Score = 38.5 bits (88), Expect = 0.009
Identities = 23/58 (39%), Positives = 27/58 (46%), Gaps = 6/58 (10%)
Query: 137 RRGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGG 194
R+ G G GG+GG GG G G R G G GG G+GG G G+ GG
Sbjct: 328 RQEGGGGRGGWGGGGGGGGRGGGGGGGG------RGGWGGGGGGWGGGGGGGGGWGGG 379
Score = 35.4 bits (80), Expect = 0.076
Identities = 21/41 (51%), Positives = 21/41 (51%), Gaps = 7/41 (17%)
Query: 119 GGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNNY 159
GGRGGY G G G Y GG G GG GG GGY Y
Sbjct: 400 GGRGGYGGRGYGDPYG----GGGGGGGGGGG---GGGYRRY 433
Score = 33.1 bits (74), Expect = 0.38
Identities = 17/29 (58%), Positives = 19/29 (65%), Gaps = 1/29 (3%)
Query: 316 DGLGGYGRGGGGSGGYYGQGGMSGGGWRG 344
+G GG G GGG GG G+GG GGG RG
Sbjct: 330 EGGGGRGGWGGGGGG-GGRGGGGGGGGRG 357
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.144 0.457
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,005,911
Number of Sequences: 37866
Number of extensions: 1026036
Number of successful extensions: 16642
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 280
Number of HSP's successfully gapped in prelim test: 202
Number of HSP's that attempted gapping in prelim test: 4953
Number of HSP's gapped (non-prelim): 5123
length of query: 346
length of database: 18,247,518
effective HSP length: 103
effective length of query: 243
effective length of database: 14,347,320
effective search space: 3486398760
effective search space used: 3486398760
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.