Search of human proteins with 14140236

Search of human proteins with 14140236

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14140236 solute carrier family 5 (low affinity glucose
cotransporter), member 4 [Homo sapiens]
         (659 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14140236 solute carrier family 5 (low affinity glucose cotran...  1317   0.0  
gi|4507031 solute carrier family 5 (sodium/glucose cotransporter...   971   0.0  
gi|4507033 solute carrier family 5 (sodium/glucose cotransporter...   785   0.0  
gi|206597483 solute carrier family 5 (sodium/glucose cotransport...   692   0.0  
gi|206597487 solute carrier family 5 (sodium/glucose cotransport...   678   0.0  
gi|17941285 solute carrier family 5 (sodium/glucose cotransporte...   645   0.0  
gi|109659836 solute carrier family 5 (sodium/glucose cotransport...   600   e-171
gi|109659839 solute carrier family 5 (sodium/glucose cotransport...   592   e-169
gi|110835708 solute carrier family 5 (inositol transporters), me...   572   e-163
gi|157671931 solute carrier family 5 (sodium/glucose cotransport...   132   8e-31
gi|10863879 solute carrier family 5 (sodium-dependent vitamin tr...   115   1e-25
gi|4507035 solute carrier family 5 (sodium iodide symporter), me...   112   1e-24
gi|167466278 solute carrier family 5 (iodide transporter), membe...   100   7e-21
gi|11141885 solute carrier family 5 (choline transporter), membe...    91   4e-18
gi|29788987 solute carrier family 24 member 4 isoform 3 [Homo sa...    35   0.17 
gi|29788985 solute carrier family 24 member 4 isoform 2 precurso...    35   0.17 
gi|24111228 solute carrier family 24 member 4 isoform 1 precurso...    35   0.17 
gi|11545853 concentrative Na+-nucleoside cotransporter [Homo sap...    32   1.4  
gi|7657587 solute carrier family 6 (neurotransmitter transporter...    32   1.9  
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]                31   4.1  
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]                 31   4.1  
gi|5729970 claudin 16 [Homo sapiens]                                   30   7.1  
gi|4506743 ribosomal protein S8 [Homo sapiens]                         30   7.1  
gi|53793658 olfactory receptor, family 10, subfamily A, member 3...    30   7.1  
gi|166197666 putative homeodomain transcription factor 1 [Homo s...    30   9.2  
gi|157885806 chromosome 12 open reading frame 51 [Homo sapiens]        30   9.2  
gi|31563526 solute carrier family 24 (sodium/potassium/calcium e...    30   9.2  

>gi|14140236 solute carrier family 5 (low affinity glucose
           cotransporter), member 4 [Homo sapiens]
          Length = 659

 Score = 1317 bits (3408), Expect = 0.0
 Identities = 659/659 (100%), Positives = 659/659 (100%)

Query: 1   MASTVSPSTIAETPEPPPLSDHIRNAADISVIVIYFLVVMAVGLWAMLKTNRGTIGGFFL 60
           MASTVSPSTIAETPEPPPLSDHIRNAADISVIVIYFLVVMAVGLWAMLKTNRGTIGGFFL
Sbjct: 1   MASTVSPSTIAETPEPPPLSDHIRNAADISVIVIYFLVVMAVGLWAMLKTNRGTIGGFFL 60

Query: 61  AGRDMAWWPMGASLFASNIGSNHYVGLAGTGAASGVATVTFEWTSSVMLLILGWIFVPIY 120
           AGRDMAWWPMGASLFASNIGSNHYVGLAGTGAASGVATVTFEWTSSVMLLILGWIFVPIY
Sbjct: 61  AGRDMAWWPMGASLFASNIGSNHYVGLAGTGAASGVATVTFEWTSSVMLLILGWIFVPIY 120

Query: 121 IKSGVMTMPEYLKKRFGGERLQVYLSILSLFICVVLLISADIFAGAIFIKLALGLDLYLA 180
           IKSGVMTMPEYLKKRFGGERLQVYLSILSLFICVVLLISADIFAGAIFIKLALGLDLYLA
Sbjct: 121 IKSGVMTMPEYLKKRFGGERLQVYLSILSLFICVVLLISADIFAGAIFIKLALGLDLYLA 180

Query: 181 IFILLAMTAVYTTTGGLASVIYTDTLQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNAT 240
           IFILLAMTAVYTTTGGLASVIYTDTLQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNAT
Sbjct: 181 IFILLAMTAVYTTTGGLASVIYTDTLQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNAT 240

Query: 241 PSVVEGDNLTISASCYTPRADSFHIFRDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQR 300
           PSVVEGDNLTISASCYTPRADSFHIFRDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQR
Sbjct: 241 PSVVEGDNLTISASCYTPRADSFHIFRDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQR 300

Query: 301 CLCGKDMSHVKAACIMCAYLKLLPMFLMVMPGMISRILYTDMVACVVPSECVKHCGVDVG 360
           CLCGKDMSHVKAACIMCAYLKLLPMFLMVMPGMISRILYTDMVACVVPSECVKHCGVDVG
Sbjct: 301 CLCGKDMSHVKAACIMCAYLKLLPMFLMVMPGMISRILYTDMVACVVPSECVKHCGVDVG 360

Query: 361 CTNYAYPTMVLELMPQGLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASEK 420
           CTNYAYPTMVLELMPQGLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASEK
Sbjct: 361 CTNYAYPTMVLELMPQGLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASEK 420

Query: 421 ELLIAGRIFVLLLTVVSIVWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRV 480
           ELLIAGRIFVLLLTVVSIVWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRV
Sbjct: 421 ELLIAGRIFVLLLTVVSIVWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRV 480

Query: 481 NEQGAFWGLMVGLAMGLIRMITEFAYGTGSCLAPSNCPKIICGVHYLYFSIVLFFGSMLV 540
           NEQGAFWGLMVGLAMGLIRMITEFAYGTGSCLAPSNCPKIICGVHYLYFSIVLFFGSMLV
Sbjct: 481 NEQGAFWGLMVGLAMGLIRMITEFAYGTGSCLAPSNCPKIICGVHYLYFSIVLFFGSMLV 540

Query: 541 TLGISLLTKPIPDVHLYRLCWVLRNSTEERIDIDAEEKSQEETDDGVEEDYPEKSRGCLK 600
           TLGISLLTKPIPDVHLYRLCWVLRNSTEERIDIDAEEKSQEETDDGVEEDYPEKSRGCLK
Sbjct: 541 TLGISLLTKPIPDVHLYRLCWVLRNSTEERIDIDAEEKSQEETDDGVEEDYPEKSRGCLK 600

Query: 601 KAYDLFCGLQKGPKLTKEEEEALSKKLTDTSERPSWRTIVNINAILLLAVVVFIHGYYA 659
           KAYDLFCGLQKGPKLTKEEEEALSKKLTDTSERPSWRTIVNINAILLLAVVVFIHGYYA
Sbjct: 601 KAYDLFCGLQKGPKLTKEEEEALSKKLTDTSERPSWRTIVNINAILLLAVVVFIHGYYA 659


>gi|4507031 solute carrier family 5 (sodium/glucose cotransporter),
           member 1 [Homo sapiens]
          Length = 664

 Score =  971 bits (2509), Expect = 0.0
 Identities = 465/663 (70%), Positives = 559/663 (84%), Gaps = 6/663 (0%)

Query: 2   ASTVSPSTIAETPEPPPLSDHIRNAADISVIVIYFLVVMAVGLWAMLKTNRGTIGGFFLA 61
           +ST SP T A T  P    + IRNAADIS+IVIYF+VVMAVGLWAM  TNRGT+GGFFLA
Sbjct: 3   SSTWSPKTTAVT-RPVETHELIRNAADISIIVIYFVVVMAVGLWAMFSTNRGTVGGFFLA 61

Query: 62  GRDMAWWPMGASLFASNIGSNHYVGLAGTGAASGVATVTFEWTSSVMLLILGWIFVPIYI 121
           GR M WWP+GASLFASNIGS H+VGLAGTGAASG+A   FEW + V++++LGW+FVPIYI
Sbjct: 62  GRSMVWWPIGASLFASNIGSGHFVGLAGTGAASGIAIGGFEWNALVLVVVLGWLFVPIYI 121

Query: 122 KSGVMTMPEYLKKRFGGERLQVYLSILSLFICVVLLISADIFAGAIFIKLALGLDLYLAI 181
           K+GV+TMPEYL+KRFGG+R+QVYLS+LSL + +   ISADIF+GAIFI LALGL+LYLAI
Sbjct: 122 KAGVVTMPEYLRKRFGGQRIQVYLSLLSLLLYIFTKISADIFSGAIFINLALGLNLYLAI 181

Query: 182 FILLAMTAVYTTTGGLASVIYTDTLQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATP 241
           F+LLA+TA+YT TGGLA+VIYTDTLQT+IML+GS IL GFAF+EVGGY++F EKY+ A P
Sbjct: 182 FLLLAITALYTITGGLAAVIYTDTLQTVIMLVGSLILTGFAFHEVGGYDAFMEKYMKAIP 241

Query: 242 SVVEGDNLTISASCYTPRADSFHIFRDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQRC 301
           ++V   N T    CYTPRADSFHIFRD +TGD+PWPG IFGM I  LWYWCT+QVIVQRC
Sbjct: 242 TIVSDGNTTFQEKCYTPRADSFHIFRDPLTGDLPWPGFIFGMSILTLWYWCTDQVIVQRC 301

Query: 302 LCGKDMSHVKAACIMCAYLKLLPMFLMVMPGMISRILYTDMVACVVPSECVKHCGVDVGC 361
           L  K+MSHVK  CI+C YLKL+PMF+MVMPGMISRILYT+ +ACVVPSEC K+CG  VGC
Sbjct: 302 LSAKNMSHVKGGCILCGYLKLMPMFIMVMPGMISRILYTEKIACVVPSECEKYCGTKVGC 361

Query: 362 TNYAYPTMVLELMPQGLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASEKE 421
           TN AYPT+V+ELMP GLRGLMLSVMLASLMSSLTSIFNSASTLFT+D+Y K+RK+ASEKE
Sbjct: 362 TNIAYPTLVVELMPNGLRGLMLSVMLASLMSSLTSIFNSASTLFTMDIYAKVRKRASEKE 421

Query: 422 LLIAGRIFVLLLTVVSIVWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRVN 481
           L+IAGR+F+L+L  +SI WVP+VQ +Q+GQL  Y +SI+SYLGPPIAAVF+LAIF KRVN
Sbjct: 422 LMIAGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRVN 481

Query: 482 EQGAFWGLMVGLAMGLIRMITEFAYGTGSCLAPSNCPKIICGVHYLYFSIVLFFGSMLVT 541
           E GAFWGL++GL +G+ RMITEFAYGTGSC+ PSNCP IICGVHYLYF+I+LF  S +  
Sbjct: 482 EPGAFWGLILGLLIGISRMITEFAYGTGSCMEPSNCPTIICGVHYLYFAIILFAISFITI 541

Query: 542 LGISLLTKPIPDVHLYRLCWVLRNSTEERIDIDAEEKSQEETDD---GVEEDYPEKSRGC 598
           + ISLLTKPIPDVHLYRLCW LRNS EERID+DAEE++ +E       +E   PEK +G 
Sbjct: 542 VVISLLTKPIPDVHLYRLCWSLRNSKEERIDLDAEEENIQEGPKETIEIETQVPEKKKGI 601

Query: 599 LKKAYDLFCGLQK--GPKLTKEEEEALSKKLTDTSERPSWRTIVNINAILLLAVVVFIHG 656
            ++AYDLFCGL++   PK+T+EEE+A+  K+TDTSE+P WRT++N+N I+L+ V VF H 
Sbjct: 602 FRRAYDLFCGLEQHGAPKMTEEEEKAMKMKMTDTSEKPLWRTVLNVNGIILVTVAVFCHA 661

Query: 657 YYA 659
           Y+A
Sbjct: 662 YFA 664


>gi|4507033 solute carrier family 5 (sodium/glucose cotransporter),
           member 2 [Homo sapiens]
          Length = 672

 Score =  785 bits (2027), Expect = 0.0
 Identities = 371/653 (56%), Positives = 499/653 (76%), Gaps = 16/653 (2%)

Query: 23  IRNAADISVIVIYFLVVMAVGLWAMLKTNRGTIGGFFLAGRDMAWWPMGASLFASNIGSN 82
           I N ADI VI  YFL+V+ VGLW+M +TNRGT+GG+FLAGR M WWP+GASLFASNIGS 
Sbjct: 20  IDNPADILVIAAYFLLVIGVGLWSMCRTNRGTVGGYFLAGRSMVWWPVGASLFASNIGSG 79

Query: 83  HYVGLAGTGAASGVATVTFEWTSSVMLLILGWIFVPIYIKSGVMTMPEYLKKRFGGERLQ 142
           H+VGLAGTGAASG+A   FEW +  ++L+LGW+F P+Y+ +GV+TMP+YL+KRFGG R++
Sbjct: 80  HFVGLAGTGAASGLAVAGFEWNALFVVLLLGWLFAPVYLTAGVITMPQYLRKRFGGRRIR 139

Query: 143 VYLSILSLFICVVLLISADIFAGAIFIKLALGLDLYLAIFILLAMTAVYTTTGGLASVIY 202
           +YLS+LSLF+ +   IS D+F+GA+FI+ ALG ++Y ++  LL +T +YT TGGLA+++Y
Sbjct: 140 LYLSVLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTGGLAALMY 199

Query: 203 TDTLQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATPSVVEGDNLT---ISASCYTPR 259
           TDT+QT ++L G+ ILMG+AF+EVGGY    +KY+ A  S+   ++     IS+ CY PR
Sbjct: 200 TDTVQTFVILGGACILMGYAFHEVGGYSGLFDKYLGAATSLTVSEDPAVGNISSFCYRPR 259

Query: 260 ADSFHIFRDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQRCLCGKDMSHVKAACIMCAY 319
            DS+H+ R  VTGD+PWP ++ G+ I + WYWC++QVIVQRCL GK ++H+KA CI+C Y
Sbjct: 260 PDSYHLLRHPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQRCLAGKSLTHIKAGCILCGY 319

Query: 320 LKLLPMFLMVMPGMISRILYTDMVACVVPSECVKHCGVDVGCTNYAYPTMVLELMPQGLR 379
           LKL PMFLMVMPGMISRILY D VACVVP  C + CG +VGC+N AYP +V++LMP GLR
Sbjct: 320 LKLTPMFLMVMPGMISRILYPDEVACVVPEVCRRVCGTEVGCSNIAYPRLVVKLMPNGLR 379

Query: 380 GLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASEKELLIAGRIFVLLLTVVSIV 439
           GLML+VMLA+LMSSL SIFNS+STLFT+D+YT++R +A ++ELL+ GR++V+ + VVS+ 
Sbjct: 380 GLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGDRELLLVGRLWVVFIVVVSVA 439

Query: 440 WVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRVNEQGAFWGLMVGLAMGLIR 499
           W+P+VQ +Q GQL  Y +++SSYL PP++AVFVLA+F  RVNEQGAFWGL+ GL MGL R
Sbjct: 440 WLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFVLALFVPRVNEQGAFWGLIGGLLMGLAR 499

Query: 500 MITEFAYGTGSCLAPSNCPKIICGVHYLYFSIVLFFGSMLVTLGISLLTKPIPDVHLYRL 559
           +I EF++G+GSC+ PS CP  +CGVHYLYF+IVLFF S L+TL +SL T PIP  HL+RL
Sbjct: 500 LIPEFSFGSGSCVQPSACPAFLCGVHYLYFAIVLFFCSGLLTLTVSLCTAPIPRKHLHRL 559

Query: 560 CWVLRNSTEERIDIDAEEK--SQEETDDGVEEDYPEKSR------GCLKKAYDLFCGLQK 611
            + LR+S EER D+DA+E+  S     +G  E   E +          ++    FCG+ +
Sbjct: 560 VFSLRHSKEEREDLDADEQQGSSLPVQNGCPESAMEMNEPQAPAPSLFRQCLLWFCGMSR 619

Query: 612 G-----PKLTKEEEEALSKKLTDTSERPSWRTIVNINAILLLAVVVFIHGYYA 659
           G     P LT+EE  A +++L D SE PSW  +VN+NA+L++AV VF+ G+YA
Sbjct: 620 GGVGSPPPLTQEEAAAAARRLEDISEDPSWARVVNLNALLMMAVAVFLWGFYA 672


>gi|206597483 solute carrier family 5 (sodium/glucose
           cotransporter), member 9 isoform 2 [Homo sapiens]
          Length = 681

 Score =  692 bits (1785), Expect = 0.0
 Identities = 336/653 (51%), Positives = 466/653 (71%), Gaps = 23/653 (3%)

Query: 25  NAADISVIVIYFLVVMAVGLWAMLKTNRGTIGGFFLAGRDMAWWPMGASLFASNIGSNHY 84
           +A DISV+VIYF+ V+AVG+W+ ++ +RGTIGG+FLAGR M+WWP+GASL +SN+GS  +
Sbjct: 34  HAYDISVVVIYFVFVIAVGIWSSIRASRGTIGGYFLAGRSMSWWPIGASLMSSNVGSGLF 93

Query: 85  VGLAGTGAASGVATVTFEWTSSVMLLILGWIFVPIYIKSGVMTMPEYLKKRFGGERLQVY 144
           +GLAGTGAA G+A   FEW ++ +LL LGW+FVP+YI +GV+TMP+YLKKRFGG+R+QVY
Sbjct: 94  IGLAGTGAAGGLAVGGFEWNATWLLLALGWVFVPVYIAAGVVTMPQYLKKRFGGQRIQVY 153

Query: 145 LSILSLFICVVLLISADIFAGAIFIKLALGLDLYLAIFILLAMTAVYTTTGGLASVIYTD 204
           +S+LSL + +   IS DIF+GA+FI++ALG +LYL+  ILL +TAVYT  GGL +VIYTD
Sbjct: 154 MSVLSLILYIFTKISTDIFSGALFIQMALGWNLYLSTGILLVVTAVYTIAGGLMAVIYTD 213

Query: 205 TLQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATPSVVEGDNLTISASCYTPRADSFH 264
            LQT+IM+ G+ +LM   F +VG Y    ++Y  A P+V        + +C+ PR D+FH
Sbjct: 214 ALQTVIMVGGALVLMFLGFQDVGWYPGLEQRYRQAIPNVT-----VPNTTCHLPRPDAFH 268

Query: 265 IFRDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQRCLCGKDMSHVKAACIMCAYLKLLP 324
           I RD V+GDIPWPG+IFG+ + A W WCT+QVIVQR L  K +SH K   ++  YLK+LP
Sbjct: 269 ILRDPVSGDIPWPGLIFGLTVLATWCWCTDQVIVQRSLSAKSLSHAKGGSVLGGYLKILP 328

Query: 325 MFLMVMPGMISRILYTDMVACVVPSECVKHCGVDVGCTNYAYPTMVLELMPQGLRGLMLS 384
           MF +VMPGMISR L+ D V CV P  C + CG  VGC+N AYP +V+ LMP GLRGLM++
Sbjct: 329 MFFIVMPGMISRALFPDEVGCVDPDVCQRICGARVGCSNIAYPKLVMALMPVGLRGLMIA 388

Query: 385 VMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASEKELLIAGRIFVLLLTVVSIVWVPLV 444
           V++A+LMSSLTSIFNS+STLFTID++ + R++++E+EL++ GR+FV+ L V+SI+W+P++
Sbjct: 389 VIMAALMSSLTSIFNSSSTLFTIDVWQRFRRKSTEQELMVVGRVFVVFLVVISILWIPII 448

Query: 445 QVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRVNEQGAFWGLMVGLAMGLIRMITEF 504
           Q S +GQL  Y ++++SYL PPI A+F+LAIFCKRV E GAFWGL+ GL +GL+RMI EF
Sbjct: 449 QSSNSGQLFDYIQAVTSYLAPPITALFLLAIFCKRVTEPGAFWGLVFGLGVGLLRMILEF 508

Query: 505 AYGTGSCLAPSNCPKIICGVHYLYFSIVLFFGSMLVTLGISLLTKPIPDVHLYRLCWVLR 564
           +Y   +C      P ++   HYLYF+I+L   + +V + +SL T PIP+  L RL W  R
Sbjct: 509 SYPAPACGEVDRRPAVLKDFHYLYFAILLCGLTAIVIVIVSLCTTPIPEEQLTRLTWWTR 568

Query: 565 NSTEERIDIDAEEKSQEETD---------------DGVEEDYPE-KSRGCLKKAYDLFCG 608
           N     ++ +A E + E ++                 + ++ PE  SR   K  +  FCG
Sbjct: 569 NCPLSELEKEAHESTPEISERPAGECPAGGGAAENSSLGQEQPEAPSRSWGKLLWSWFCG 628

Query: 609 LQKGPK--LTKEEEEALSKKLTDTSERPSWRTIVNINAILLLAVVVFIHGYYA 659
           L   P+  L+  E+ AL +KLT   E P WR + NINA+LLLA+ +F+ GY+A
Sbjct: 629 LSGTPEQALSPAEKAALEQKLTSIEEEPLWRHVCNINAVLLLAINIFLWGYFA 681


>gi|206597487 solute carrier family 5 (sodium/glucose
           cotransporter), member 9 isoform 1 [Homo sapiens]
          Length = 706

 Score =  678 bits (1749), Expect = 0.0
 Identities = 336/678 (49%), Positives = 466/678 (68%), Gaps = 48/678 (7%)

Query: 25  NAADISVIVIYFLVVMAVGLWAMLKTNRGTIGGFFLAGRDMAWWPMGASLFASNIGSNHY 84
           +A DISV+VIYF+ V+AVG+W+ ++ +RGTIGG+FLAGR M+WWP+GASL +SN+GS  +
Sbjct: 34  HAYDISVVVIYFVFVIAVGIWSSIRASRGTIGGYFLAGRSMSWWPIGASLMSSNVGSGLF 93

Query: 85  VGLAGTGAASGVATVTFEWT-------------------------SSVMLLILGWIFVPI 119
           +GLAGTGAA G+A   FEW                          ++ +LL LGW+FVP+
Sbjct: 94  IGLAGTGAAGGLAVGGFEWNMRKSRSGGDRGIHPRSHGRTGVRSQATWLLLALGWVFVPV 153

Query: 120 YIKSGVMTMPEYLKKRFGGERLQVYLSILSLFICVVLLISADIFAGAIFIKLALGLDLYL 179
           YI +GV+TMP+YLKKRFGG+R+QVY+S+LSL + +   IS DIF+GA+FI++ALG +LYL
Sbjct: 154 YIAAGVVTMPQYLKKRFGGQRIQVYMSVLSLILYIFTKISTDIFSGALFIQMALGWNLYL 213

Query: 180 AIFILLAMTAVYTTTGGLASVIYTDTLQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNA 239
           +  ILL +TAVYT  GGL +VIYTD LQT+IM+ G+ +LM   F +VG Y    ++Y  A
Sbjct: 214 STGILLVVTAVYTIAGGLMAVIYTDALQTVIMVGGALVLMFLGFQDVGWYPGLEQRYRQA 273

Query: 240 TPSVVEGDNLTISASCYTPRADSFHIFRDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQ 299
            P+V        + +C+ PR D+FHI RD V+GDIPWPG+IFG+ + A W WCT+QVIVQ
Sbjct: 274 IPNVT-----VPNTTCHLPRPDAFHILRDPVSGDIPWPGLIFGLTVLATWCWCTDQVIVQ 328

Query: 300 RCLCGKDMSHVKAACIMCAYLKLLPMFLMVMPGMISRILYTDMVACVVPSECVKHCGVDV 359
           R L  K +SH K   ++  YLK+LPMF +VMPGMISR L+ D V CV P  C + CG  V
Sbjct: 329 RSLSAKSLSHAKGGSVLGGYLKILPMFFIVMPGMISRALFPDEVGCVDPDVCQRICGARV 388

Query: 360 GCTNYAYPTMVLELMPQGLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASE 419
           GC+N AYP +V+ LMP GLRGLM++V++A+LMSSLTSIFNS+STLFTID++ + R++++E
Sbjct: 389 GCSNIAYPKLVMALMPVGLRGLMIAVIMAALMSSLTSIFNSSSTLFTIDVWQRFRRKSTE 448

Query: 420 KELLIAGRIFVLLLTVVSIVWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKR 479
           +EL++ GR+FV+ L V+SI+W+P++Q S +GQL  Y ++++SYL PPI A+F+LAIFCKR
Sbjct: 449 QELMVVGRVFVVFLVVISILWIPIIQSSNSGQLFDYIQAVTSYLAPPITALFLLAIFCKR 508

Query: 480 VNEQGAFWGLMVGLAMGLIRMITEFAYGTGSCLAPSNCPKIICGVHYLYFSIVLFFGSML 539
           V E GAFWGL+ GL +GL+RMI EF+Y   +C      P ++   HYLYF+I+L   + +
Sbjct: 509 VTEPGAFWGLVFGLGVGLLRMILEFSYPAPACGEVDRRPAVLKDFHYLYFAILLCGLTAI 568

Query: 540 VTLGISLLTKPIPDVHLYRLCWVLRNSTEERIDIDAEEKSQEETD--------------- 584
           V + +SL T PIP+  L RL W  RN     ++ +A E + E ++               
Sbjct: 569 VIVIVSLCTTPIPEEQLTRLTWWTRNCPLSELEKEAHESTPEISERPAGECPAGGGAAEN 628

Query: 585 DGVEEDYPE-KSRGCLKKAYDLFCGLQKGPK--LTKEEEEALSKKLTDTSERPSWRTIVN 641
             + ++ PE  SR   K  +  FCGL   P+  L+  E+ AL +KLT   E P WR + N
Sbjct: 629 SSLGQEQPEAPSRSWGKLLWSWFCGLSGTPEQALSPAEKAALEQKLTSIEEEPLWRHVCN 688

Query: 642 INAILLLAVVVFIHGYYA 659
           INA+LLLA+ +F+ GY+A
Sbjct: 689 INAVLLLAINIFLWGYFA 706


>gi|17941285 solute carrier family 5 (sodium/glucose cotransporter),
           member 11 [Homo sapiens]
          Length = 675

 Score =  645 bits (1664), Expect = 0.0
 Identities = 332/677 (49%), Positives = 450/677 (66%), Gaps = 38/677 (5%)

Query: 13  TPEPPPLS------DHIRNAADISVIVIYFLVVMAVGLWAMLKTNRGTIGGFFLAGRDMA 66
           +P+PP L              DI+V+V+YFL V+AVGLW+ +KT R T+ G+FLAG DM 
Sbjct: 7   SPQPPQLDPLDAFPQKGLEPGDIAVLVLYFLFVLAVGLWSTVKTKRDTVKGYFLAGGDMV 66

Query: 67  WWPMGASLFASNIGSNHYVGLAGTGAASGVATVTFEWTSSVMLLILGWIFVPIYIKSGVM 126
           WWP+GASLFASN+GS H++GLAG+GAA+G++   +E      +L+L WIF+PIYI   V 
Sbjct: 67  WWPVGASLFASNVGSGHFIGLAGSGAATGISVSAYELNGLFSVLMLAWIFLPIYIAGQVT 126

Query: 127 TMPEYLKKRFGGERLQVYLSILSLFICVVLLISADIFAGAIFIKLALGLDLYLAIFILLA 186
           TMPEYL+KRFGG R+ + L++L LFI +   IS D++AGAIFI+ +L LDLYLAI  LLA
Sbjct: 127 TMPEYLRKRFGGIRIPIILAVLYLFIYIFTKISVDMYAGAIFIQQSLHLDLYLAIVGLLA 186

Query: 187 MTAVYTTTGGLASVIYTDTLQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATPSVVEG 246
           +TAVYT  GGLA+VIYTD LQT+IMLIG+  LMG++F  VGG E   EKY  A  S    
Sbjct: 187 ITAVYTVAGGLAAVIYTDALQTLIMLIGALTLMGYSFAAVGGMEGLKEKYFLALAS---- 242

Query: 247 DNLTISASCYTPRADSFHIFRDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQRCLCGKD 306
            N + ++SC  PR D+FHIFRD +T D+PWPG++FGM I +LWYWCT+QVIVQR L  K+
Sbjct: 243 -NRSENSSCGLPREDAFHIFRDPLTSDLPWPGVLFGMSIPSLWYWCTDQVIVQRTLAAKN 301

Query: 307 MSHVKAACIMCAYLKLLPMFLMVMPGMISRILYTDMVACVVPSECVKHCGVDVGCTNYAY 366
           +SH K   +M AYLK+LP+F+MV PGM+SRIL+ D VAC  P  C K C    GC++ AY
Sbjct: 302 LSHAKGGALMAAYLKVLPLFIMVFPGMVSRILFPDQVACADPEICQKICSNPSGCSDIAY 361

Query: 367 PTMVLELMPQGLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASEKELLIAG 426
           P +VLEL+P GLRGLM++VM+A+LMSSLTSIFNSAST+FT+DL+  +R +ASEKEL+I G
Sbjct: 362 PKLVLELLPTGLRGLMMAVMVAALMSSLTSIFNSASTIFTMDLWNHLRPRASEKELMIVG 421

Query: 427 RIFVLLLTVVSIVWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRVNEQGAF 486
           R+FVLLL +VSI+W+P+VQ SQ GQL  Y +SISSYL PP+A VF++  F KR NE+GAF
Sbjct: 422 RVFVLLLVLVSILWIPVVQASQGGQLFIYIQSISSYLQPPVAVVFIMGCFWKRTNEKGAF 481

Query: 487 WGLMVGLAMGLIRMITEFAYGTGSCLAPSNCPKIICGVHYLYFSIVLFFGSMLVTLGISL 546
           WGL+ GL +GL+R++ +F Y    C  P   P ++  +HYLYFS++L   +++    +S 
Sbjct: 482 WGLISGLLLGLVRLVLDFIYVQPRCDQPDERPVLVKSIHYLYFSMILSTVTLITVSTVSW 541

Query: 547 LTKPIPDVHLYRLCWVLRNS---TEERIDIDA------------EEKSQEETDDGVEEDY 591
            T+P     +  L W  R+     +E+    A            E  S       + ++ 
Sbjct: 542 FTEPPSKEMVSHLTWFTRHDPVVQKEQAPPAAPLSLTLSQNGMPEASSSSSVQFEMVQEN 601

Query: 592 PEKSRGC--------LKKAYDLFCGLQ-KGPKLTKEEEEALSKKLTDTSERPSWRTIVNI 642
             K+  C        + KA    CG+Q KG +      EA+   +    E P  +T++++
Sbjct: 602 TSKTHSCDMTPKQSKVVKAILWLCGIQEKGKEELPARAEAI---IVSLEENPLVKTLLDV 658

Query: 643 NAILLLAVVVFIHGYYA 659
           N I  ++  +FI GY+A
Sbjct: 659 NLIFCVSCAIFIWGYFA 675


>gi|109659836 solute carrier family 5 (sodium/glucose
           cotransporter), member 10 isoform 2 [Homo sapiens]
          Length = 596

 Score =  600 bits (1547), Expect = e-171
 Identities = 278/537 (51%), Positives = 391/537 (72%), Gaps = 5/537 (0%)

Query: 25  NAADISVIVIYFLVVMAVGLWAMLKTNRGTIGGFFLAGRDMAWWPMGASLFASNIGSNHY 84
           + ADI VI +YF + +AVG+W+  + +R T+ G+FLAGRDM WWP+GASLFAS+ GS  +
Sbjct: 17  SVADIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAGRDMTWWPIGASLFASSEGSGLF 76

Query: 85  VGLAGTGAASGVATVTFEWTSSVMLLILGWIFVPIYIKSGVMTMPEYLKKRFGGERLQVY 144
           +GLAG+GAA G+A   FEW ++ +LL L W+FVPIYI S ++T+PEY++KR+GG+R+++Y
Sbjct: 77  IGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYIQKRYGGQRIRMY 136

Query: 145 LSILSLFICVVLLISADIFAGAIFIKLALGLDLYLAIFILLAMTAVYTTTGGLASVIYTD 204
           LS+LSL + V   IS D++AGA+F+ + LG + YL+  + L +TA+YT  GGLA+VIYTD
Sbjct: 137 LSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYTD 196

Query: 205 TLQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATPSVVEGDNLTISASCYTPRADSFH 264
            LQT+IM++G+ IL   AF+++GGY      Y  A PS         + +C+ PR D+ H
Sbjct: 197 ALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPS-----RTIANTTCHLPRTDAMH 251

Query: 265 IFRDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQRCLCGKDMSHVKAACIMCAYLKLLP 324
           +FRD  TGD+PW G+ FG+ I A WYWCT+QVIVQR L  +D++H KA  I+ +YLK+LP
Sbjct: 252 MFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILASYLKMLP 311

Query: 325 MFLMVMPGMISRILYTDMVACVVPSECVKHCGVDVGCTNYAYPTMVLELMPQGLRGLMLS 384
           M L++MPGMISR L+ D V CVVPSEC++ CG +VGC+N AYP +V+ELMP GLRGLM++
Sbjct: 312 MGLIIMPGMISRALFPDDVGCVVPSECLRACGAEVGCSNIAYPKLVMELMPIGLRGLMIA 371

Query: 385 VMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASEKELLIAGRIFVLLLTVVSIVWVPLV 444
           VMLA+LMSSLTSIFNS+STLFT+D++ ++R ++ E+ELL+ GR+ ++ L  VS+ W+P++
Sbjct: 372 VMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGRLVIVALIGVSVAWIPVL 431

Query: 445 QVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRVNEQGAFWGLMVGLAMGLIRMITEF 504
           Q S +GQL  Y +S++S L PP+ AVFVL +F +R NEQGAFWGL+ GL +G  R++ EF
Sbjct: 432 QDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFWGLIAGLVVGATRLVLEF 491

Query: 505 AYGTGSCLAPSNCPKIICGVHYLYFSIVLFFGSMLVTLGISLLTKPIPDVHLYRLCW 561
                 C  P   P ++  +HYL+F++ LF  S  V +  SLLT P   V +  L W
Sbjct: 492 LNPAPPCGEPDTRPAVLGSIHYLHFAVALFALSGAVVVAGSLLTPPPQSVQIENLTW 548


>gi|109659839 solute carrier family 5 (sodium/glucose
           cotransporter), member 10 isoform 1 [Homo sapiens]
          Length = 612

 Score =  592 bits (1526), Expect = e-169
 Identities = 279/553 (50%), Positives = 392/553 (70%), Gaps = 21/553 (3%)

Query: 25  NAADISVIVIYFLVVMAVGLWAMLKTNRGTIGGFFLAGRDMAWWPMGASLFASNIGSNHY 84
           + ADI VI +YF + +AVG+W+  + +R T+ G+FLAGRDM WWP+GASLFAS+ GS  +
Sbjct: 17  SVADIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAGRDMTWWPIGASLFASSEGSGLF 76

Query: 85  VGLAGTGAASGVATVTFEWTSSVMLLILGWIFVPIYIKSGVMTMPEYLKKRFGGERLQVY 144
           +GLAG+GAA G+A   FEW ++ +LL L W+FVPIYI S ++T+PEY++KR+GG+R+++Y
Sbjct: 77  IGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYIQKRYGGQRIRMY 136

Query: 145 LSILSLFICVVLLISADIFAGAIFIKLALGLDLYLAIFILLAMTAVYTTTGGLASVIYTD 204
           LS+LSL + V   IS D++AGA+F+ + LG + YL+  + L +TA+YT  GGLA+VIYTD
Sbjct: 137 LSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYTD 196

Query: 205 TLQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATPSVVEGDNLTISASCYTPRADSFH 264
            LQT+IM++G+ IL   AF+++GGY      Y  A PS         + +C+ PR D+ H
Sbjct: 197 ALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPS-----RTIANTTCHLPRTDAMH 251

Query: 265 IFRDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQRCLCGKDMSHVKAACIMCAYLKLLP 324
           +FRD  TGD+PW G+ FG+ I A WYWCT+QVIVQR L  +D++H KA  I+ +YLK+LP
Sbjct: 252 MFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILASYLKMLP 311

Query: 325 MFLMVMPGMISRILY----------------TDMVACVVPSECVKHCGVDVGCTNYAYPT 368
           M L++MPGMISR L+                TD V CVVPSEC++ CG +VGC+N AYP 
Sbjct: 312 MGLIIMPGMISRALFPGAHVYEERHQVSVSRTDDVGCVVPSECLRACGAEVGCSNIAYPK 371

Query: 369 MVLELMPQGLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASEKELLIAGRI 428
           +V+ELMP GLRGLM++VMLA+LMSSLTSIFNS+STLFT+D++ ++R ++ E+ELL+ GR+
Sbjct: 372 LVMELMPIGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGRL 431

Query: 429 FVLLLTVVSIVWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRVNEQGAFWG 488
            ++ L  VS+ W+P++Q S +GQL  Y +S++S L PP+ AVFVL +F +R NEQGAFWG
Sbjct: 432 VIVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFWG 491

Query: 489 LMVGLAMGLIRMITEFAYGTGSCLAPSNCPKIICGVHYLYFSIVLFFGSMLVTLGISLLT 548
           L+ GL +G  R++ EF      C  P   P ++  +HYL+F++ LF  S  V +  SLLT
Sbjct: 492 LIAGLVVGATRLVLEFLNPAPPCGEPDTRPAVLGSIHYLHFAVALFALSGAVVVAGSLLT 551

Query: 549 KPIPDVHLYRLCW 561
            P   V +  L W
Sbjct: 552 PPPQSVQIENLTW 564


>gi|110835708 solute carrier family 5 (inositol transporters),
           member 3 [Homo sapiens]
          Length = 718

 Score =  572 bits (1473), Expect = e-163
 Identities = 267/532 (50%), Positives = 387/532 (72%), Gaps = 4/532 (0%)

Query: 23  IRNAADISVIVIYFLVVMAVGLWAMLKTNRGTIGGFFLAGRDMAWWPMGASLFASNIGSN 82
           + + ADI+++ +YF++VM +G +AM K+NR T+ G+FLAGR M W  +GASLF SNIGS 
Sbjct: 4   VLDTADIAIVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVTIGASLFVSNIGSE 63

Query: 83  HYVGLAGTGAASGVATVTFEWTSSVMLLILGWIFVPIYIKSGVMTMPEYLKKRFGGERLQ 142
           H++GLAG+GAASG A   +E+ + ++L +LGW+F+PIYI+SGV TMPEYL KRFGG R+Q
Sbjct: 64  HFIGLAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGHRIQ 123

Query: 143 VYLSILSLFICVVLLISADIFAGAIFIKLALGLDLYLAIFILLAMTAVYTTTGGLASVIY 202
           VY + LSL + +   +S D+++GA+FI+ +LG +LY+++ +L+ MTA+ T TGGL +VIY
Sbjct: 124 VYFAALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIY 183

Query: 203 TDTLQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATP---SVVEGDNLTISASC-YTP 258
           TDTLQ ++M+IG+  LM  +  E+GG+E    +Y+ A+P   S++   NL+ + SC  +P
Sbjct: 184 TDTLQALLMIIGALTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSNTNSCNVSP 243

Query: 259 RADSFHIFRDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQRCLCGKDMSHVKAACIMCA 318
           + ++  + R+    D+PWPG I G    ++WYWC +QVIVQR L  K+++H K + +M  
Sbjct: 244 KKEALKMLRNPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAG 303

Query: 319 YLKLLPMFLMVMPGMISRILYTDMVACVVPSECVKHCGVDVGCTNYAYPTMVLELMPQGL 378
           +LKLLPMF++V+PGMISRIL+TD +AC+ P  C+  CG   GC+N AYP +V++L+P GL
Sbjct: 304 FLKLLPMFIIVVPGMISRILFTDDIACINPEHCMLVCGSRAGCSNIAYPRLVMKLVPVGL 363

Query: 379 RGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASEKELLIAGRIFVLLLTVVSI 438
           RGLM++VM+A+LMS L SIFNSAST+FT+D+Y  +RK AS +EL+I GRIFV  + V+SI
Sbjct: 364 RGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVVISI 423

Query: 439 VWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRVNEQGAFWGLMVGLAMGLI 498
            WVP++   Q GQ+  Y + ++ YL PP+AA+F+LAIF KR NEQGAF+G M G  +G +
Sbjct: 424 AWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVLGAV 483

Query: 499 RMITEFAYGTGSCLAPSNCPKIICGVHYLYFSIVLFFGSMLVTLGISLLTKP 550
           R+I  FAY    C  P N P  I  +HY+Y +  LF+ + L+T+ +SLLT P
Sbjct: 484 RLILAFAYRAPECDQPDNRPGFIKDIHYMYVATGLFWVTGLITVIVSLLTPP 535


>gi|157671931 solute carrier family 5 (sodium/glucose
           cotransporter), member 12 [Homo sapiens]
          Length = 618

 Score =  132 bits (333), Expect = 8e-31
 Identities = 128/551 (23%), Positives = 229/551 (41%), Gaps = 64/551 (11%)

Query: 28  DISVIVIYFLVVMAVGLWAMLKTNR-GTIGGFFLAGRDMAWWPMGASLFASNIGSNHYVG 86
           D  V    F +   +G++  +K  +  T   F + GR M++ P+G SL AS + +   +G
Sbjct: 10  DYVVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTASFMSAVTVLG 69

Query: 87  LAGTGAASGVATVTFEWTSSVMLLILGWIFVPIYIKSGVMTMPEYLKKRFGGERLQVYLS 146
                   G + + F      ++L+   +F+P++ +SG+ +  EYL+ RF   +   Y +
Sbjct: 70  TPSEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRFN--KPVRYAA 127

Query: 147 ILSLFICVVLLISADIFAGAIFIKLALGLDLYLAIFILLAMTAVYTTTGGLASVIYTDTL 206
            +   +  +L     ++A A+ +    G DL+ ++F    +   Y T GGL +V++TD  
Sbjct: 128 TVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAVVWTDAF 187

Query: 207 QTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATPSVVEGDNLTISASCYTPRADSFHIF 266
           Q ++M++G   ++       GG+ +  E+  N +                  R   F   
Sbjct: 188 QMVVMIVGFLTVLIQGSTHAGGFHNVLEQSTNGS------------------RLHIFDFD 229

Query: 267 RDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQRCLCGKDMSHVKAACIMCAYLKLLPMF 326
            D +     W  I  G   T L  +  NQ  +QRC+  K   H K A     Y  LL ++
Sbjct: 230 VDPLRRHTFWT-ITVGGTFTWLGIYGVNQSTIQRCISCKTEKHAKLA----LYFNLLGLW 284

Query: 327 LMVMPGMIS-RILYTDMVACVVPSECVKHCGVDVGCTNYAYPTMVLEL---MPQGLRGLM 382
           ++++  + S  I+Y+         +C       +   +   P  V+E+   MP GL GL 
Sbjct: 285 IILVCAVFSGLIMYSHF------KDCDPWTSGIISAPDQLMPYFVMEIFATMP-GLPGLF 337

Query: 383 LSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASEKELLIAGRIFVLLLTVVSIVWVP 442
           ++   +  +S++ S  N+ +T+   D         S+K      +   LL  V+      
Sbjct: 338 VACAFSGTLSTVASSINALATVTFEDFVKSCFPHLSDKLSTWISKGLCLLFGVMCTSMA- 396

Query: 443 LVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRVNEQGAFWGLMVGLAMGLIRMIT 502
            V  S  G ++  + SI    G P+  +F L I    VN +GA  GL+ G+ +     I 
Sbjct: 397 -VAASVMGGVVQASLSIHGMCGGPMLGLFSLGIVFPFVNWKGALGGLLTGITLSFWVAIG 455

Query: 503 EFAY------------GTGSCL---APSNCPKIIC----------GVHYLYFSIVLFFGS 537
            F Y             T  C+     +  P ++            + YLY+S V   G 
Sbjct: 456 AFIYPAPASKTWPLPLSTDQCIKSNVTATGPPVLSSRPGIADTWYSISYLYYSAVGCLGC 515

Query: 538 MLVTLGISLLT 548
           ++  + ISL+T
Sbjct: 516 IVAGVIISLIT 526


>gi|10863879 solute carrier family 5 (sodium-dependent vitamin
           transporter), member 6 [Homo sapiens]
          Length = 635

 Score =  115 bits (288), Expect = 1e-25
 Identities = 118/496 (23%), Positives = 209/496 (42%), Gaps = 45/496 (9%)

Query: 28  DISVIVIYFLVVMAVGLW-AMLKTNRGTIGGFFLAGRDMAWWPMGASLFASNIGSNHYVG 86
           D  V V+  ++ +A+GL+ A     R T+G   +A R M   P+  SL A+   +   +G
Sbjct: 28  DYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPVALSLLATFQSAVAILG 87

Query: 87  LAGTGAASGVATVTFEWTSSVMLLILGWIFVPIYIKSGVMTMPEYLKKRFGGERLQVYLS 146
           +       G           + LLI   IF+P++ +  + +  EYL+ RF  + ++V  +
Sbjct: 88  VPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYEYLELRFN-KTVRVCGT 146

Query: 147 ILSLFICVVLLISADIFAGAIFIKLALGLDLYLAIFILLAMTAVYTTTGGLASVIYTDTL 206
           +  +F  V+ +    ++A ++ +    G DL+L++  L  +  VYT  GGL +VI+TD  
Sbjct: 147 VTFIFQMVIYM-GVVLYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGLKAVIWTDVF 205

Query: 207 QTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATPSVVEGDNLTISASCYTPRADSFHIF 266
           QT++M +G   ++     +VGG                       + +    R   F + 
Sbjct: 206 QTLVMFLGQLAVIIVGSAKVGGL------------------GRVWAVASQHGRISGFELD 247

Query: 267 RDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQRCLCGKDMSHVKAACIMCAYLKLLPMF 326
            D       W  + FG     L  +  NQ  VQR L  +       +C      + + + 
Sbjct: 248 PDPFVRHTFWT-LAFGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAVFPFQQVSLC 306

Query: 327 LMVMPGMISRILYTD-----MVACVVPSECVKHCGVDVGCTNYAYPTMVLELMPQGLRGL 381
           +  + G++    Y +       A   P + V +  +D+           L+ +P GL GL
Sbjct: 307 VGCLIGLVMFAYYQEYPMSIQQAQAAPDQFVLYFVMDL-----------LKGLP-GLPGL 354

Query: 382 MLSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASEKE--LLIAGRIFVLLLTVVSIV 439
            ++ + +  +S+++S FNS +T+   DL      + SE    +L  G  F   L  + + 
Sbjct: 355 FIACLFSGSLSTISSAFNSLATVTMEDLIRPWFPEFSEARAIMLSRGLAFGYGLLCLGMA 414

Query: 440 WVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRVNEQGAFWGLMVGLAMGLIR 499
           ++     SQ G ++    SI   +G P+  +F L +F    N  GA  GL+ GL M    
Sbjct: 415 YIS----SQMGPVLQAAISIFGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAGLVMAFWI 470

Query: 500 MITEFAYGTGSCLAPS 515
            I       G  + PS
Sbjct: 471 GIGSIVTSMGFSMPPS 486


>gi|4507035 solute carrier family 5 (sodium iodide symporter),
           member 5 [Homo sapiens]
          Length = 643

 Score =  112 bits (280), Expect = 1e-24
 Identities = 111/498 (22%), Positives = 208/498 (41%), Gaps = 57/498 (11%)

Query: 12  ETPEPPPLSDHIRNAADISVIVIYFLVVMAVGLWAML-KTNRGTIGGFFLAGRDMAWWPM 70
           ET E P        A D  V  +  LV   +GLW  L +  + +   FF  GR +A  P+
Sbjct: 5   ETGERPTFG-----AWDYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPV 59

Query: 71  GASLFASNIGSNHYVGLAGTGAASGVATVTFEWTSSVMLL---ILGWIFVPIYIKSGVMT 127
           G SL AS + +   +G+       G+    F W     LL   +   +F+P++ + G+ +
Sbjct: 60  GLSLSASFMSAVQVLGVPSEAYRYGLK---FLWMCLGQLLNSVLTALLFMPVFYRLGLTS 116

Query: 128 MPEYLKKRFGGERLQVYLSILSLFICVVLLISADIFAGAIFIKLALGLDLYLAIFILLAM 187
             EYL+ RF   R       L   +  +L     I+A A+ +    GLD++ ++     +
Sbjct: 117 TYEYLEMRFS--RAVRLCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGII 174

Query: 188 TAVYTTTGGLASVIYTDTLQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATPSVVEGD 247
              YT  GG+ +V++TD  Q ++ML G ++++      VGG               +  +
Sbjct: 175 CTFYTAVGGMKAVVWTDVFQVVVMLSGFWVVLARGVMLVGGPRQVL---------TLAQN 225

Query: 248 NLTISASCYTPRADSFHIFRDAVTGDIPWPGIIFGMPITALW--YWCTNQVIVQRCLCGK 305
           +  I+   + P   S + F         W  ++ G   T +W   +  NQ  VQR +  +
Sbjct: 226 HSRINLMDFNPDPRSRYTF---------WTFVVGG---TLVWLSMYGVNQAQVQRYVACR 273

Query: 306 DMSHVKAACIMCAYLKLLPMFLMVMP----GMISRILYTDMVACVVPSECVKHCGVDVGC 361
                K A +    +  + +FL+V      G++  + YTD    ++           +  
Sbjct: 274 TEKQAKLALL----INQVGLFLIVSSAACCGIVMFVFYTDCDPLLLGR---------ISA 320

Query: 362 TNYAYPTMVLELMPQ--GLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASE 419
            +   P +VL++     G+ GL L+   +  +S+ ++  N+ + +   DL     +  + 
Sbjct: 321 PDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDLIKPRLRSLAP 380

Query: 420 KELLIAGRIFVLLLTVVSIVWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKR 479
           ++L+I  +   L+     +  V  +     G ++  + ++   +  P+   F+L +F   
Sbjct: 381 RKLVIISKGLSLIYGSACLT-VAALSSLLGGGVLQGSFTVMGVISGPLLGAFILGMFLPA 439

Query: 480 VNEQGAFWGLMVGLAMGL 497
            N  G   GL  GLA+ L
Sbjct: 440 CNTPGVLAGLGAGLALSL 457


>gi|167466278 solute carrier family 5 (iodide transporter), member 8
           [Homo sapiens]
          Length = 610

 Score = 99.8 bits (247), Expect = 7e-21
 Identities = 116/475 (24%), Positives = 193/475 (40%), Gaps = 39/475 (8%)

Query: 28  DISVIVIYFLVVMAVGLW-AMLKTNRGTIGGFFLAGRDMAWWPMGASLFASNIGSNHYVG 86
           D  V     ++  A+G++ A     + T   F + GR M   P+  SL AS + +   +G
Sbjct: 14  DYVVFAGMLVISAAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALSLTASFMSAVTVLG 73

Query: 87  LAGTGAASGVATVTFEWTSSVMLLILGWIFVPIYIKSGVMTMPEYLKKRFGGERLQVYLS 146
                   G     F +T   +++I   +F+P++ K G+ +  EYL+ RF      V L 
Sbjct: 74  TPSEVYRFGAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLELRF---NKCVRLC 130

Query: 147 ILSLFIC-VVLLISADIFAGAIFIKLALGLDLYLAIFILLAMTAVYTTTGGLASVIYTDT 205
              LFI   +L     I+A A+ +    G DL+ A+     +   Y T GGL +VI+TD 
Sbjct: 131 GTVLFIVQTILYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAVIWTDV 190

Query: 206 LQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATPSVVEGDNLTISASCYTPRADSFHI 265
            Q  IM+ G                 F    + A   V++G   TI    Y     +F  
Sbjct: 191 FQVGIMVAG-----------------FASVIIQAV--VMQGGISTILNDAYDGGRLNFWN 231

Query: 266 FRDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQRCLCGKDMSHVKAACIMCAYLKLLPM 325
           F         +  II G   T    +  NQ  VQR +  K     K    +  Y+ L+ +
Sbjct: 232 FNPNPLQRHTFWTIIIGGTFTWTSIYGVNQSQVQRYISCKSRFQAK----LSLYINLVGL 287

Query: 326 FLMVMPGMISRI-LYTDMVACVVPSECVKHCGVDVGCTNYAYPTMVLELMPQ--GLRGLM 382
           + ++   +   + LY+         +C       V   +   P +VL+++    GL GL 
Sbjct: 288 WAILTCSVFCGLALYSRY------HDCDPWTAKKVSAPDQLMPYLVLDILQDYPGLPGLF 341

Query: 383 LSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASEKELLIAGRIFVLLLTVVSIVWVP 442
           ++   +  +S+++S  N+ + +   DL     +  SE+ L    +   ++   + I    
Sbjct: 342 VACAYSGTLSTVSSSINALAAVTVEDLIKPYFRSLSERSLSWISQGMSVVYGALCIGMAA 401

Query: 443 LVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRVNEQGAFWGLMVGLAMGL 497
           L   S  G L+    S+   +G P+  +F L I     N  GA  GLM G A+ L
Sbjct: 402 L--ASLMGALLQAALSVFGMVGGPLMGLFALGILVPFANSIGALVGLMAGFAISL 454


>gi|11141885 solute carrier family 5 (choline transporter), member 7
           [Homo sapiens]
          Length = 580

 Score = 90.5 bits (223), Expect = 4e-18
 Identities = 116/488 (23%), Positives = 203/488 (41%), Gaps = 81/488 (16%)

Query: 32  IVIYFLVVMAVGLWAMLKT-NRGTIG----GFFLAGRDMAWWPMGASLFASNIGSNHYVG 86
           I++++L+++ VG+WA  +T N G+         + GRD+     G ++ A+ +G  +  G
Sbjct: 11  IIVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYING 70

Query: 87  LA------GTGAASGVATVTFEWTSSVMLLILGWIFVPIYIKS-GVMTMPEYLKKRFGGE 139
            A      G G A   A + +      + LILG +F    ++S G +TM +  +      
Sbjct: 71  TAEAVYVPGYGLAWAQAPIGYS-----LSLILGGLFFAKPMRSKGYVTMLDPFQ------ 119

Query: 140 RLQVYLSILSLFICVVLLISADIFAGAIF------IKLALGLDLYLAIFILLAMTAVYTT 193
             Q+Y   +   + +  L+    +A AIF      I + + +D+++++ I   +  +YT 
Sbjct: 120 --QIYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDMHISVIISALIATLYTL 177

Query: 194 TGGLASVIYTDTLQTIIMLIGSFILMGFAFNEVG----GYESFTEKYVNATPSVVEGDNL 249
            GGL SV YTD +Q   + +G +I + FA +       G+ +   KY       V+    
Sbjct: 178 VGGLYSVAYTDVVQLFCIFVGLWISVPFALSHPAVADIGFTAVHAKYQKPWLGTVD---- 233

Query: 250 TISASCYTPRADSFHIFRDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQRCLCGKDMSH 309
             S+  Y+   DSF +    + G IPW                  Q   QR L     ++
Sbjct: 234 --SSEVYS-WLDSFLLL---MLGGIPW------------------QAYFQRVLSSSSATY 269

Query: 310 VKAACIMCAYLKLLPMFLMVMPGMISRILYTDMVACVVPSECVKHCGVDVGCTNYA---Y 366
            +    + A+  L+     ++ G I      +  A  +P         D   T  A    
Sbjct: 270 AQVLSFLAAFGCLVMAIPAILIGAIGASTDWNQTAYGLP---------DPKTTEEADMIL 320

Query: 367 PTMVLELMPQGLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLY-TKMRKQASEKELLIA 425
           P ++  L P  +    L  + A++MSS  S   SAS++F  ++Y    R+ AS+KE++  
Sbjct: 321 PIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDKEIVWV 380

Query: 426 GRIFVLLLTVVSIVWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRVNEQGA 485
            RI V +    +     L +       + Y  S   Y+   I    +  +F K  N  GA
Sbjct: 381 MRITVFVFGASATAMALLTKTVYG---LWYLSSDLVYI--VIFPQLLCVLFVKGTNTYGA 435

Query: 486 FWGLMVGL 493
             G + GL
Sbjct: 436 VAGYVSGL 443


>gi|29788987 solute carrier family 24 member 4 isoform 3 [Homo
           sapiens]
          Length = 558

 Score = 35.4 bits (80), Expect = 0.17
 Identities = 24/97 (24%), Positives = 49/97 (50%), Gaps = 3/97 (3%)

Query: 70  MGASLFASNIGSNHYVGLAGTGAASGVATVTFEWTSSVMLLILGWIFVPIYIKSGV--MT 127
           +G    ++ IGSN +  L G G   G+ T+   + S+V +   G ++  + +   V    
Sbjct: 450 LGDMAVSNTIGSNVFDILVGLGVPWGLQTMVVNYGSTVKINSRGLVYSVVLLLGSVALTV 509

Query: 128 MPEYLKKRFGGERLQVYLSIL-SLFICVVLLISADIF 163
           +  +L K     +L VY+ +L ++F+C  ++I  ++F
Sbjct: 510 LGIHLNKWRLDRKLGVYVLVLYAIFLCFSIMIEFNVF 546


>gi|29788985 solute carrier family 24 member 4 isoform 2 precursor
           [Homo sapiens]
          Length = 586

 Score = 35.4 bits (80), Expect = 0.17
 Identities = 24/97 (24%), Positives = 49/97 (50%), Gaps = 3/97 (3%)

Query: 70  MGASLFASNIGSNHYVGLAGTGAASGVATVTFEWTSSVMLLILGWIFVPIYIKSGV--MT 127
           +G    ++ IGSN +  L G G   G+ T+   + S+V +   G ++  + +   V    
Sbjct: 478 LGDMAVSNTIGSNVFDILVGLGVPWGLQTMVVNYGSTVKINSRGLVYSVVLLLGSVALTV 537

Query: 128 MPEYLKKRFGGERLQVYLSIL-SLFICVVLLISADIF 163
           +  +L K     +L VY+ +L ++F+C  ++I  ++F
Sbjct: 538 LGIHLNKWRLDRKLGVYVLVLYAIFLCFSIMIEFNVF 574


>gi|24111228 solute carrier family 24 member 4 isoform 1 precursor
           [Homo sapiens]
          Length = 605

 Score = 35.4 bits (80), Expect = 0.17
 Identities = 24/97 (24%), Positives = 49/97 (50%), Gaps = 3/97 (3%)

Query: 70  MGASLFASNIGSNHYVGLAGTGAASGVATVTFEWTSSVMLLILGWIFVPIYIKSGV--MT 127
           +G    ++ IGSN +  L G G   G+ T+   + S+V +   G ++  + +   V    
Sbjct: 497 LGDMAVSNTIGSNVFDILVGLGVPWGLQTMVVNYGSTVKINSRGLVYSVVLLLGSVALTV 556

Query: 128 MPEYLKKRFGGERLQVYLSIL-SLFICVVLLISADIF 163
           +  +L K     +L VY+ +L ++F+C  ++I  ++F
Sbjct: 557 LGIHLNKWRLDRKLGVYVLVLYAIFLCFSIMIEFNVF 593


>gi|11545853 concentrative Na+-nucleoside cotransporter [Homo
           sapiens]
          Length = 691

 Score = 32.3 bits (72), Expect = 1.4
 Identities = 13/52 (25%), Positives = 26/52 (50%)

Query: 565 NSTEERIDIDAEEKSQEETDDGVEEDYPEKSRGCLKKAYDLFCGLQKGPKLT 616
           N+ ++   +  E+ S    +   ++D   + +GCL++ YD  CG  +  K T
Sbjct: 49  NTKQDEEQVTVEQDSPRNREHMEDDDEEMQQKGCLERRYDTVCGFCRKHKTT 100


>gi|7657587 solute carrier family 6 (neurotransmitter transporter,
           GABA), member 11 [Homo sapiens]
          Length = 632

 Score = 32.0 bits (71), Expect = 1.9
 Identities = 34/120 (28%), Positives = 54/120 (45%), Gaps = 13/120 (10%)

Query: 360 GCTNYAYPTMVLELMPQGLRGLMLSVMLASLMSSLTSIFNSASTLFT--IDLYTKMRKQA 417
           G    AYP  V  +    L   +  +ML  L   L S F    +L T  +D+Y K+ ++ 
Sbjct: 376 GLAFIAYPKAVTMMPLSPLWATLFFMMLIFL--GLDSQFVCVESLVTAVVDMYPKVFRRG 433

Query: 418 SEKELLIAGRIFVLLLTVVSIVWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFC 477
             +ELLI      L L+V+S  ++ LV +++ G  I   +   SY    +  +FV    C
Sbjct: 434 YRRELLI------LALSVIS-YFLGLVMLTEGGMYIF--QLFDSYAASGMCLLFVAIFEC 484


>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
          Length = 755

 Score = 30.8 bits (68), Expect = 4.1
 Identities = 23/61 (37%), Positives = 32/61 (52%), Gaps = 4/61 (6%)

Query: 574 DAEEKSQEETDDGVEEDYPEKSRGCLKKAYD-LFCGLQKGPKLTKEEEEALSKKLTDTSE 632
           DA+EK  EE+DD  +ED   K    ++ A + LF       KL  EEE++  K   D+ E
Sbjct: 667 DADEKLFEESDDKEDEDADGKE---VEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDE 723

Query: 633 R 633
           R
Sbjct: 724 R 724


>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
          Length = 755

 Score = 30.8 bits (68), Expect = 4.1
 Identities = 23/61 (37%), Positives = 32/61 (52%), Gaps = 4/61 (6%)

Query: 574 DAEEKSQEETDDGVEEDYPEKSRGCLKKAYD-LFCGLQKGPKLTKEEEEALSKKLTDTSE 632
           DA+EK  EE+DD  +ED   K    ++ A + LF       KL  EEE++  K   D+ E
Sbjct: 667 DADEKLFEESDDKEDEDADGKE---VEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDE 723

Query: 633 R 633
           R
Sbjct: 724 R 724


>gi|5729970 claudin 16 [Homo sapiens]
          Length = 305

 Score = 30.0 bits (66), Expect = 7.1
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 11/66 (16%)

Query: 148 LSLFICVVLLISADIFAGAIFIKLALGLDL--------YLAI---FILLAMTAVYTTTGG 196
           L L +   L+I+ADI AG  F+ L LGLD         Y+ +   F+  A   +  T G 
Sbjct: 143 LKLVVTRALMITADILAGFGFLTLLLGLDCVKFLPDEPYIKVRICFVAGATLLIAGTPGI 202

Query: 197 LASVIY 202
           + SV Y
Sbjct: 203 IGSVWY 208


>gi|4506743 ribosomal protein S8 [Homo sapiens]
          Length = 208

 Score = 30.0 bits (66), Expect = 7.1
 Identities = 15/24 (62%), Positives = 17/24 (70%)

Query: 603 YDLFCGLQKGPKLTKEEEEALSKK 626
           Y L  G +KG KLT EEEE L+KK
Sbjct: 117 YALPLGRKKGAKLTPEEEEILNKK 140


>gi|53793658 olfactory receptor, family 10, subfamily A, member 3
           [Homo sapiens]
          Length = 314

 Score = 30.0 bits (66), Expect = 7.1
 Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 1/92 (1%)

Query: 141 LQVYLSILSLFICVVLLISADIFAGAIFIKLALGLDLYLAIFILLAMTAVYTTTGGLASV 200
           LQV L  + L I VV L+   I    I +  +L + +YL +  L  +   ++       +
Sbjct: 23  LQVQLFGVFLVIYVVTLMGNAIITVIISLNQSLHVPMYLFLLNLSVVEVSFSAVITPEML 82

Query: 201 IYTDTLQTIIMLIGSFILMGFAFNEVGGYESF 232
           +   T +T+I  +G F  M F     GG E F
Sbjct: 83  VVLSTEKTMISFVGCFAQMYFIL-LFGGTECF 113


>gi|166197666 putative homeodomain transcription factor 1 [Homo
           sapiens]
          Length = 762

 Score = 29.6 bits (65), Expect = 9.2
 Identities = 18/45 (40%), Positives = 27/45 (60%), Gaps = 2/45 (4%)

Query: 381 LMLSVMLASLMSSLTSIFNSASTLFT--IDLYTKMRKQASEKELL 423
           L+  + LASL S     +++ S L T  I+LY KM K+ ++KE L
Sbjct: 655 LLFLLRLASLGSETNKKYSNVSILLTEQINLYLKMEKKPNKKEQL 699


>gi|157885806 chromosome 12 open reading frame 51 [Homo sapiens]
          Length = 3996

 Score = 29.6 bits (65), Expect = 9.2
 Identities = 17/61 (27%), Positives = 29/61 (47%), Gaps = 2/61 (3%)

Query: 315 IMCAYLKLLPMFLMVMPGMISRILYTDMVACVVPSECVKHCGVDVGCTNYAYPTMVLELM 374
           +M   L+ L M   +MP ++  +LYT   A ++ ++C      +VGC+    P     L 
Sbjct: 550 LMHPNLQTLIMADALMPQLVQLVLYTSQTALLLKTQCPVF--AEVGCSPCGAPDQKCRLF 607

Query: 375 P 375
           P
Sbjct: 608 P 608


>gi|31563526 solute carrier family 24 (sodium/potassium/calcium
           exchanger), member 3 [Homo sapiens]
          Length = 644

 Score = 29.6 bits (65), Expect = 9.2
 Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 17/104 (16%)

Query: 70  MGASLFASNIGSNHYVGLAGTGAASGVATVTFEWTSSVML----------LILGWIFVPI 119
           MG    +++IGSN +  L G G    + T+  ++ S + L          L+L  +FV +
Sbjct: 537 MGDMAVSNSIGSNVFDILIGLGLPWALQTLAVDYGSYIRLNSRGLIYSVGLLLASVFVTV 596

Query: 120 YIKSGVMTMPEYLKKRFGGERLQVYLSILSLFICVVLLISADIF 163
           +   GV      L K+ G   L +Y     +F+C  ++   ++F
Sbjct: 597 F---GVHLNKWQLDKKLGCGCLLLY----GVFLCFSIMTEFNVF 633


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.140    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,442,692
Number of Sequences: 37866
Number of extensions: 1003044
Number of successful extensions: 4425
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 4368
Number of HSP's gapped (non-prelim): 38
length of query: 659
length of database: 18,247,518
effective HSP length: 109
effective length of query: 550
effective length of database: 14,120,124
effective search space: 7766068200
effective search space used: 7766068200
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.