Guide to the Human Genome
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Search of human proteins with 14043022

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14043022 methionyl-tRNA synthetase [Homo sapiens]
         (900 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14043022 methionyl-tRNA synthetase [Homo sapiens]                 1834   0.0  
gi|24308436 methionine-tRNA synthetase 2 precursor [Homo sapiens]     126   8e-29
gi|62241042 glutamyl-prolyl tRNA synthetase [Homo sapiens]             47   8e-05
gi|5454158 valyl-tRNA synthetase [Homo sapiens]                        43   0.002
gi|6996014 histidyl-tRNA synthetase [Homo sapiens]                     40   0.007
gi|7661872 leucyl-tRNA synthetase 2, mitochondrial precursor [Ho...    38   0.037
gi|47419916 tryptophanyl-tRNA synthetase isoform a [Homo sapiens]      38   0.037
gi|47419914 tryptophanyl-tRNA synthetase isoform a [Homo sapiens]      38   0.037
gi|4503481 eukaryotic translation elongation factor 1 gamma [Hom...    38   0.048
gi|51873055 fibulin 2 isoform b precursor [Homo sapiens]               37   0.11 
gi|51873053 fibulin 2 isoform a precursor [Homo sapiens]               37   0.11 
gi|38488767 microtubule associated serine/threonine kinase famil...    34   0.54 
gi|12025678 actinin, alpha 4 [Homo sapiens]                            34   0.70 
gi|30089948 protein phosphatase 1E [Homo sapiens]                      33   0.91 
gi|116256333 membrane metallo-endopeptidase [Homo sapiens]             33   1.2  
gi|116256331 membrane metallo-endopeptidase [Homo sapiens]             33   1.2  
gi|116256327 membrane metallo-endopeptidase [Homo sapiens]             33   1.2  
gi|116256329 membrane metallo-endopeptidase [Homo sapiens]             33   1.2  
gi|198041678 solute carrier family 12 (potassium-chloride transp...    32   2.0  
gi|11968148 solute carrier family 12 (potassium-chloride transpo...    32   2.0  
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi...    32   2.0  
gi|46852147 mitochondrial isoleucine tRNA synthetase [Homo sapiens]    32   2.7  
gi|167466164 glutathione S-transferase theta 1 [Homo sapiens]          31   4.5  
gi|194097352 actinin, alpha 1 isoform c [Homo sapiens]                 31   4.5  
gi|194097350 actinin, alpha 1 isoform a [Homo sapiens]                 31   4.5  
gi|4501891 actinin, alpha 1 isoform b [Homo sapiens]                   31   4.5  
gi|239755252 PREDICTED: hypothetical protein [Homo sapiens]            31   5.9  
gi|169201936 PREDICTED: hypothetical protein [Homo sapiens]            31   5.9  
gi|169191966 PREDICTED: hypothetical protein [Homo sapiens]            31   5.9  
gi|94721239 isoleucine tRNA synthetase [Homo sapiens]                  31   5.9  

>gi|14043022 methionyl-tRNA synthetase [Homo sapiens]
          Length = 900

 Score = 1834 bits (4751), Expect = 0.0
 Identities = 900/900 (100%), Positives = 900/900 (100%)

Query: 1   MRLFVSDGVPGCLPVLAAAGRARGRAEVLISTVGPEDCVVPFLTRPKVPVLQLDSGNYLF 60
           MRLFVSDGVPGCLPVLAAAGRARGRAEVLISTVGPEDCVVPFLTRPKVPVLQLDSGNYLF
Sbjct: 1   MRLFVSDGVPGCLPVLAAAGRARGRAEVLISTVGPEDCVVPFLTRPKVPVLQLDSGNYLF 60

Query: 61  STSAICRYFFLLSGWEQDDLTNQWLEWEATELQPALSAALYYLVVQGKKGEDVLGSVRRA 120
           STSAICRYFFLLSGWEQDDLTNQWLEWEATELQPALSAALYYLVVQGKKGEDVLGSVRRA
Sbjct: 61  STSAICRYFFLLSGWEQDDLTNQWLEWEATELQPALSAALYYLVVQGKKGEDVLGSVRRA 120

Query: 121 LTHIDHSLSRQNCPFLAGETESLADIVLWGALYPLLQDPAYLPEELSALHSWFQTLSTQE 180
           LTHIDHSLSRQNCPFLAGETESLADIVLWGALYPLLQDPAYLPEELSALHSWFQTLSTQE
Sbjct: 121 LTHIDHSLSRQNCPFLAGETESLADIVLWGALYPLLQDPAYLPEELSALHSWFQTLSTQE 180

Query: 181 PCQRAAETVLKQQGVLALRPYLQKQPQPSPAEGRAVTNEPEEEELATLSEEEIAMAVTAW 240
           PCQRAAETVLKQQGVLALRPYLQKQPQPSPAEGRAVTNEPEEEELATLSEEEIAMAVTAW
Sbjct: 181 PCQRAAETVLKQQGVLALRPYLQKQPQPSPAEGRAVTNEPEEEELATLSEEEIAMAVTAW 240

Query: 241 EKGLESLPPLRPQQNPVLPVAGERNVLITSALPYVNNVPHLGNIIGCVLSADVFARYSRL 300
           EKGLESLPPLRPQQNPVLPVAGERNVLITSALPYVNNVPHLGNIIGCVLSADVFARYSRL
Sbjct: 241 EKGLESLPPLRPQQNPVLPVAGERNVLITSALPYVNNVPHLGNIIGCVLSADVFARYSRL 300

Query: 301 RQWNTLYLCGTDEYGTATETKALEEGLTPQEICDKYHIIHADIYRWFNISFDIFGRTTTP 360
           RQWNTLYLCGTDEYGTATETKALEEGLTPQEICDKYHIIHADIYRWFNISFDIFGRTTTP
Sbjct: 301 RQWNTLYLCGTDEYGTATETKALEEGLTPQEICDKYHIIHADIYRWFNISFDIFGRTTTP 360

Query: 361 QQTKITQDIFQQLLKRGFVLQDTVEQLRCEHCARFLADRFVEGVCPFCGYEEARGDQCDK 420
           QQTKITQDIFQQLLKRGFVLQDTVEQLRCEHCARFLADRFVEGVCPFCGYEEARGDQCDK
Sbjct: 361 QQTKITQDIFQQLLKRGFVLQDTVEQLRCEHCARFLADRFVEGVCPFCGYEEARGDQCDK 420

Query: 421 CGKLINAVELKKPQCKVCRSCPVVQSSQHLFLDLPKLEKRLEEWLGRTLPGSDWTPNAQF 480
           CGKLINAVELKKPQCKVCRSCPVVQSSQHLFLDLPKLEKRLEEWLGRTLPGSDWTPNAQF
Sbjct: 421 CGKLINAVELKKPQCKVCRSCPVVQSSQHLFLDLPKLEKRLEEWLGRTLPGSDWTPNAQF 480

Query: 481 ITRSWLRDGLKPRCITRDLKWGTPVPLEGFEDKVFYVWFDATIGYLSITANYTDQWERWW 540
           ITRSWLRDGLKPRCITRDLKWGTPVPLEGFEDKVFYVWFDATIGYLSITANYTDQWERWW
Sbjct: 481 ITRSWLRDGLKPRCITRDLKWGTPVPLEGFEDKVFYVWFDATIGYLSITANYTDQWERWW 540

Query: 541 KNPEQVDLYQFMAKDNVPFHSLVFPCSALGAEDNYTLVSHLIATEYLNYEDGKFSKSRGV 600
           KNPEQVDLYQFMAKDNVPFHSLVFPCSALGAEDNYTLVSHLIATEYLNYEDGKFSKSRGV
Sbjct: 541 KNPEQVDLYQFMAKDNVPFHSLVFPCSALGAEDNYTLVSHLIATEYLNYEDGKFSKSRGV 600

Query: 601 GVFGDMAQDTGIPADIWRFYLLYIRPEGQDSAFSWTDLLLKNNSELLNNLGNFINRAGMF 660
           GVFGDMAQDTGIPADIWRFYLLYIRPEGQDSAFSWTDLLLKNNSELLNNLGNFINRAGMF
Sbjct: 601 GVFGDMAQDTGIPADIWRFYLLYIRPEGQDSAFSWTDLLLKNNSELLNNLGNFINRAGMF 660

Query: 661 VSKFFGGYVPEMVLTPDDQRLLAHVTLELQHYHQLLEKVRIRDALRSILTISRHGNQYIQ 720
           VSKFFGGYVPEMVLTPDDQRLLAHVTLELQHYHQLLEKVRIRDALRSILTISRHGNQYIQ
Sbjct: 661 VSKFFGGYVPEMVLTPDDQRLLAHVTLELQHYHQLLEKVRIRDALRSILTISRHGNQYIQ 720

Query: 721 VNEPWKRIKGSEADRQRAGTVTGLAVNIAALLSVMLQPYMPTVSATIQAQLQLPPPACSI 780
           VNEPWKRIKGSEADRQRAGTVTGLAVNIAALLSVMLQPYMPTVSATIQAQLQLPPPACSI
Sbjct: 721 VNEPWKRIKGSEADRQRAGTVTGLAVNIAALLSVMLQPYMPTVSATIQAQLQLPPPACSI 780

Query: 781 LLTNFLCTLPAGHQIGTVSPLFQKLENDQIESLRQRFGGGQAKTSPKPAVVETVTTAKPQ 840
           LLTNFLCTLPAGHQIGTVSPLFQKLENDQIESLRQRFGGGQAKTSPKPAVVETVTTAKPQ
Sbjct: 781 LLTNFLCTLPAGHQIGTVSPLFQKLENDQIESLRQRFGGGQAKTSPKPAVVETVTTAKPQ 840

Query: 841 QIQALMDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAVAEGKPPEAPKGKKKK 900
           QIQALMDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAVAEGKPPEAPKGKKKK
Sbjct: 841 QIQALMDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAVAEGKPPEAPKGKKKK 900


>gi|24308436 methionine-tRNA synthetase 2 precursor [Homo sapiens]
          Length = 593

 Score =  126 bits (317), Expect = 8e-29
 Identities = 129/524 (24%), Positives = 209/524 (39%), Gaps = 53/524 (10%)

Query: 269 TSALPYVNNVPHLGNIIGCVLSADVFARYSRLRQWNTL---YLCGTDEYGTATETKALEE 325
           T+ + YVN  PH+G++   +L AD   R+ RLR  +T    +  GTDE+G   +  A   
Sbjct: 48  TTPIFYVNAAPHIGHLYSALL-ADALCRHRRLRGPSTAATRFSTGTDEHGLKIQQAAATA 106

Query: 326 GLTPQEICDKYHIIHADIYRWFNISFDIFGRTTTPQQTKITQDIFQQLLKRGFVLQDTVE 385
           GL P E+CD+       +++   IS   F RTT  +     Q  +  L  RG + +   E
Sbjct: 107 GLAPTELCDRVSEQFQQLFQEAGISCTDFIRTTEARHRVAVQHFWGVLKSRGLLYKGVYE 166

Query: 386 QLRCEHCARFLADRFVEGVCPFCGYEEARGDQCDKCGKLINAVELKKPQCKVCRSCPVVQ 445
              C     FL +  V             GD      +  + V   K +  + R      
Sbjct: 167 GWYCASDECFLPEAKVTQ------QPGPSGDSFPVSLESGHPVSWTKEENYIFR------ 214

Query: 446 SSQHLFLDLPKLEKRLEEWLGRTLPGSDWTPNAQFITRSWLRDGLKPRCITR---DLKWG 502
                   L +  K L+ WL R  P +        +   WL + L    ++R    L WG
Sbjct: 215 --------LSQFRKPLQRWL-RGNPQAITPEPFHHVVLQWLDEELPDLSVSRRSSHLHWG 265

Query: 503 TPVPLEGFEDKVFYVWFDATIGYLSITANYTDQWERWWKNPEQVDLYQFMAKDNVPFHSL 562
            PVP  G + +  YVW DA + YL++      +++ WW     +     + KD + FH++
Sbjct: 266 IPVP--GDDSQTIYVWLDALVNYLTVIGYPNAEFKSWWPATSHI-----IGKDILKFHAI 318

Query: 563 VFPCSALGAEDNYTLVSHLIATEYLNYEDGKFSKSRGVGVFGDMAQDTGIPADIWRFYLL 622
            +P   LGA    +    +    +      K SKS G  V            D +R++LL
Sbjct: 319 YWPAFLLGA--GMSPPQRICVHSHWTVCGQKMSKSLG-NVVDPRTCLNRYTVDGFRYFLL 375

Query: 623 YIRPEGQDSAFSWTDLLLKNNSELLNNLGNFINRAGM-----------FVSKFF----GG 667
                  D  +    ++   NSEL + LG  +NR              F +  F    G 
Sbjct: 376 RQGVPNWDCDYYDEKVVKLLNSELADALGGLLNRCTAKRINPSETYPAFCTTCFPSEPGL 435

Query: 668 YVPEMVLTPDDQRLLAHVTLELQHYHQLLEKVRIRDALRSILTISRHGNQYIQVNEPWKR 727
             P +    +D  L++ V    +      +  RI  AL ++ +  R  N ++Q + PWK 
Sbjct: 436 VGPSVRAQAEDYALVSAVATLPKQVADHYDNFRIYKALEAVSSCVRQTNGFVQRHAPWKL 495

Query: 728 IKGSEADRQRAGTVTGLAVNIAALLSVMLQPYMPTVSATIQAQL 771
              S  D    GTV  +A+    +   +LQP  P+++  + ++L
Sbjct: 496 NWESPVDAPWLGTVLHVALECLRVFGTLLQPVTPSLADKLLSRL 539


>gi|62241042 glutamyl-prolyl tRNA synthetase [Homo sapiens]
          Length = 1512

 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 37/112 (33%), Positives = 54/112 (48%), Gaps = 8/112 (7%)

Query: 786 LCTLPAGHQIGTVSPLFQKLENDQIESLRQRFGGGQAKTSPKPAVVETVTTAKPQQIQAL 845
           L  +P GH      P     E  ++E+ +        K  P P++    TT++   +  L
Sbjct: 699 LIYIPDGHT--KEMPTSGSKEKTKVEATKNETSA-PFKERPTPSLNNNCTTSEDSLV--L 753

Query: 846 MDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLK---KQLAVAEGKPPEAP 894
            + V  QG++VRELKA+KA K +V A V +LL LK   K+    E KP   P
Sbjct: 754 YNRVAVQGDVVRELKAKKAPKEDVDAAVKQLLSLKAEYKEKTGQEYKPGNPP 805



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 33/81 (40%), Positives = 44/81 (54%), Gaps = 13/81 (16%)

Query: 827 KPAVVETVTTAKPQQIQALMDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLK---KQL 883
           +PA +ET       + + L D+V  QG +VR+LK +KA K++V   V +LL LK   K L
Sbjct: 892 EPAGLET------PEAKVLFDKVASQGEVVRKLKTEKAPKDQVDIAVQELLQLKAQYKSL 945

Query: 884 AVAEGKPPEA----PKGKKKK 900
              E KP  A     K KKKK
Sbjct: 946 IGVEYKPVSATGAEDKDKKKK 966



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 22/59 (37%), Positives = 35/59 (59%)

Query: 831 VETVTTAKPQQIQALMDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAVAEGK 889
           + + ++A   + ++L DEV  QG +VR+LKA+K+ K ++   V  LL LK Q     GK
Sbjct: 812 ISSNSSASILESKSLYDEVAAQGEVVRKLKAEKSPKAKINEAVECLLSLKAQYKEKTGK 870


>gi|5454158 valyl-tRNA synthetase [Homo sapiens]
          Length = 1264

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 88/400 (22%), Positives = 150/400 (37%), Gaps = 77/400 (19%)

Query: 17  AAAGRARGRAEVLISTVGPEDCVVPFLTRPKVPVLQLDSGN-YLFSTSAICRYFFLLS-- 73
           A  G   G A   I    P     PF   P++P L+   G  +++  +A+ +  +     
Sbjct: 27  AGEGPGWGGAHPRICLQPPPTSRTPF-PPPRLPALEQGPGGLWVWGATAVAQLLWPAGLG 85

Query: 74  ---GWEQDDLTNQWLEWEATELQPALSAALYYLVVQGKKGED---VLGSVRRALTHIDHS 127
              G     L  QW+ +  TEL PA   A    +      +D   VLG++ RAL+ ++  
Sbjct: 86  GPGGSRAAVLVQQWVSYADTELIPAACGATLPALGLRSSAQDPQAVLGALGRALSPLEEW 145

Query: 128 LSRQNCPFLAGETESLADIVLWGAL---YPLLQDPAYLPEELSALHSWFQTLSTQEPCQR 184
           L      +LAGE  +LAD+    AL   +  + DP       + +  WF T   Q   + 
Sbjct: 146 LRLHT--YLAGEAPTLADLAAVTALLLPFRYVLDPP-ARRIWNNVTRWFVTCVRQPEFRA 202

Query: 185 AAETVLKQQGVLAL------------------------RPYLQK--------QPQPSPAE 212
               V+   G   L                        R  L+K        Q QP P E
Sbjct: 203 VLGEVVLYSGARPLSHQPGPEAPALPKTAAQLKKEAKKREKLEKFQQKQKIQQQQPPPGE 262

Query: 213 GRAVTNEPEEEELATLS---------EEEIA----------MAVTAWEKGLESLPPLRPQ 253
            +    + E+ +   ++         +++++              AW    E     +P+
Sbjct: 263 KKPKPEKREKRDPGVITYDLPTPPGEKKDVSGPMPDSYSPRYVEAAWYPWWEQQGFFKPE 322

Query: 254 Q-NPVLPVAGERNV-LITSALPYVNNVPHLGNIIGCVLSADVFARYSRLRQWNTLYLCGT 311
              P +  A  R V ++    P V    HLG+ +   +  D   R+ R+R   TL+  G 
Sbjct: 323 YGRPNVSAANPRGVFMMCIPPPNVTGSLHLGHALTNAIQ-DSLTRWHRMRGETTLWNPGC 381

Query: 312 DEYGTATET---KAL--EEGLTPQEICDKYHIIHADIYRW 346
           D  G AT+    K L  E+GL+  ++  +  +   ++++W
Sbjct: 382 DHAGIATQVVVEKKLWREQGLSRHQLGREAFL--QEVWKW 419


>gi|6996014 histidyl-tRNA synthetase [Homo sapiens]
          Length = 509

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 27/60 (45%), Positives = 34/60 (56%), Gaps = 4/60 (6%)

Query: 843 QALMDEVTK-QGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAVAEGKPP---EAPKGKK 898
           +A ++E+ K QG  VR LK QKA    +  EVAKLL LK QL   E K     + PKG +
Sbjct: 4   RAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPKGTR 63


>gi|7661872 leucyl-tRNA synthetase 2, mitochondrial precursor [Homo
           sapiens]
          Length = 903

 Score = 38.1 bits (87), Expect = 0.037
 Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 3/116 (2%)

Query: 268 ITSALPYVNNVPHLGNIIGCVLSADVFARYSRLRQWNTLYLCGTDEYGTATETKALEEGL 327
           + S  PY +   H+G++    +S D  AR+ ++R    +   G D +G   E  A+E  L
Sbjct: 86  VLSMFPYPSGKLHMGHVRVYTIS-DTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNL 144

Query: 328 TPQEICDK--YHIIHADIYRWFNISFDIFGRTTTPQQTKITQDIFQQLLKRGFVLQ 381
            PQ        H+           S+D    T  P   K TQ +F +L + G   Q
Sbjct: 145 HPQSWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQ 200


>gi|47419916 tryptophanyl-tRNA synthetase isoform a [Homo sapiens]
          Length = 471

 Score = 38.1 bits (87), Expect = 0.037
 Identities = 19/57 (33%), Positives = 31/57 (54%)

Query: 837 AKPQQIQALMDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAVAEGKPPEA 893
           ++P  +  L + +  QG +VR LKA  A K+E+ + V  L+ LK     A G+  +A
Sbjct: 4   SEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA 60


>gi|47419914 tryptophanyl-tRNA synthetase isoform a [Homo sapiens]
          Length = 471

 Score = 38.1 bits (87), Expect = 0.037
 Identities = 19/57 (33%), Positives = 31/57 (54%)

Query: 837 AKPQQIQALMDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAVAEGKPPEA 893
           ++P  +  L + +  QG +VR LKA  A K+E+ + V  L+ LK     A G+  +A
Sbjct: 4   SEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA 60


>gi|4503481 eukaryotic translation elongation factor 1 gamma [Homo
           sapiens]
          Length = 437

 Score = 37.7 bits (86), Expect = 0.048
 Identities = 49/205 (23%), Positives = 86/205 (41%), Gaps = 20/205 (9%)

Query: 47  KVPVLQLDSGNYLFSTSAICRYF----FLLSGWEQDDLTNQWLEWEATELQPALSAALY- 101
           KVP  + D G  +F ++AI  Y        S  E      QW+ +  +++ P  S  ++ 
Sbjct: 57  KVPAFEGDDGFCVFESNAIAYYVSNEELRGSTPEAAAQVVQWVSFADSDIVPPASTWVFP 116

Query: 102 --YLVVQGKKG-EDVLGSVRRALTHIDHSLSRQNCPFLAGETESLADI-----VLWGALY 153
              ++   K+  E+    VRR L  +D  L  +   FL GE  +LADI     +LW  LY
Sbjct: 117 TLGIMHHNKQATENAKEEVRRILGLLDAYLKTRT--FLVGERVTLADITVVCTLLW--LY 172

Query: 154 PLLQDPAYLPEELSALHSWFQTLSTQEPCQRAAETV--LKQQGVLALRPYLQKQPQPSPA 211
             + +P++  +     + WF T   Q   +     V   ++      + + + QP+    
Sbjct: 173 KQVLEPSF-RQAFPNTNRWFLTCINQPQFRAVLGEVKLCEKMAQFDAKKFAETQPKKDTP 231

Query: 212 EGRAVTNEPEEEELATLSEEEIAMA 236
                + E +++  A   EE+ A A
Sbjct: 232 RKEKGSREEKQKPQAERKEEKKAAA 256


>gi|51873055 fibulin 2 isoform b precursor [Homo sapiens]
          Length = 1184

 Score = 36.6 bits (83), Expect = 0.11
 Identities = 23/62 (37%), Positives = 30/62 (48%), Gaps = 4/62 (6%)

Query: 206 PQPSPAEGRAVTNEPEEEELATLSEEEIAMA---VTAWEKGLESLPPLRPQQNPVLPVAG 262
           P P  A+ R VT + EEEE      EE+A+         +GL+ LP   P   P LP+  
Sbjct: 263 PAPVQAKARRVTEDSEEEEEEEEEREEMAVTEQLAAGGHRGLDGLPTTAP-AGPSLPIQE 321

Query: 263 ER 264
           ER
Sbjct: 322 ER 323


>gi|51873053 fibulin 2 isoform a precursor [Homo sapiens]
          Length = 1231

 Score = 36.6 bits (83), Expect = 0.11
 Identities = 23/62 (37%), Positives = 30/62 (48%), Gaps = 4/62 (6%)

Query: 206 PQPSPAEGRAVTNEPEEEELATLSEEEIAMA---VTAWEKGLESLPPLRPQQNPVLPVAG 262
           P P  A+ R VT + EEEE      EE+A+         +GL+ LP   P   P LP+  
Sbjct: 263 PAPVQAKARRVTEDSEEEEEEEEEREEMAVTEQLAAGGHRGLDGLPTTAP-AGPSLPIQE 321

Query: 263 ER 264
           ER
Sbjct: 322 ER 323


>gi|38488767 microtubule associated serine/threonine kinase family
           member 4 isoform b [Homo sapiens]
          Length = 250

 Score = 34.3 bits (77), Expect = 0.54
 Identities = 19/51 (37%), Positives = 27/51 (52%)

Query: 175 TLSTQEPCQRAAETVLKQQGVLALRPYLQKQPQPSPAEGRAVTNEPEEEEL 225
           TL  + P   A  +VL ++GVLAL P L     P    G + + E ++EEL
Sbjct: 72  TLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEEL 122


>gi|12025678 actinin, alpha 4 [Homo sapiens]
          Length = 911

 Score = 33.9 bits (76), Expect = 0.70
 Identities = 14/35 (40%), Positives = 21/35 (60%)

Query: 436 KVCRSCPVVQSSQHLFLDLPKLEKRLEEWLGRTLP 470
           ++C+   V Q ++HL  D  KL   L EW+ RT+P
Sbjct: 280 RICKVLAVNQENEHLMEDYEKLASDLLEWIRRTIP 314


>gi|30089948 protein phosphatase 1E [Homo sapiens]
          Length = 755

 Score = 33.5 bits (75), Expect = 0.91
 Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 18/84 (21%)

Query: 177 STQEPCQRAAETVLKQQGVLALRPYLQKQPQPSPAEGRAVTNEPEEEELATLSEEEIAMA 236
           S +EP + AA     ++G         ++  P P E  AV  E EEE  AT         
Sbjct: 62  SVEEPGEEAATVAATEEG--------DQEQDPEPEEEAAVEGEEEEEGAAT--------- 104

Query: 237 VTAWEKGLESLPPLRPQQNPVLPV 260
             A   G  ++PP  PQ  P+ P+
Sbjct: 105 -AAAAPGHSAVPPPPPQLPPLPPL 127


>gi|116256333 membrane metallo-endopeptidase [Homo sapiens]
          Length = 750

 Score = 33.1 bits (74), Expect = 1.2
 Identities = 14/49 (28%), Positives = 31/49 (63%)

Query: 844 ALMDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAVAEGKPPE 892
           A +D +     ++R+ +    D+N++A E+ K+++L+K++A A  KP +
Sbjct: 244 AYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPED 292


>gi|116256331 membrane metallo-endopeptidase [Homo sapiens]
          Length = 750

 Score = 33.1 bits (74), Expect = 1.2
 Identities = 14/49 (28%), Positives = 31/49 (63%)

Query: 844 ALMDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAVAEGKPPE 892
           A +D +     ++R+ +    D+N++A E+ K+++L+K++A A  KP +
Sbjct: 244 AYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPED 292


>gi|116256327 membrane metallo-endopeptidase [Homo sapiens]
          Length = 750

 Score = 33.1 bits (74), Expect = 1.2
 Identities = 14/49 (28%), Positives = 31/49 (63%)

Query: 844 ALMDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAVAEGKPPE 892
           A +D +     ++R+ +    D+N++A E+ K+++L+K++A A  KP +
Sbjct: 244 AYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPED 292


>gi|116256329 membrane metallo-endopeptidase [Homo sapiens]
          Length = 750

 Score = 33.1 bits (74), Expect = 1.2
 Identities = 14/49 (28%), Positives = 31/49 (63%)

Query: 844 ALMDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAVAEGKPPE 892
           A +D +     ++R+ +    D+N++A E+ K+++L+K++A A  KP +
Sbjct: 244 AYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPED 292


>gi|198041678 solute carrier family 12 (potassium-chloride
           transporter), member 5 isoform 1 [Homo sapiens]
          Length = 1139

 Score = 32.3 bits (72), Expect = 2.0
 Identities = 35/136 (25%), Positives = 55/136 (40%), Gaps = 16/136 (11%)

Query: 730 GSEADRQRA---GTVTGLAVNIAALLS------------VMLQPYMPTVSATIQAQLQLP 774
           G   D Q++   GT+  +A   A  +S            V+   +   V+  +       
Sbjct: 445 GDLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVVGTLAW 504

Query: 775 PPACSILLTNFLCTLPAGHQIGTVSP-LFQKLENDQIESLRQRFGGGQAKTSPKPAVVET 833
           P    I++ +F  T  AG Q  T +P L Q +  D I    Q FG G+A   P  A++ T
Sbjct: 505 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLLT 564

Query: 834 VTTAKPQQIQALMDEV 849
               +   + A +DEV
Sbjct: 565 ACICEIGILIASLDEV 580


>gi|11968148 solute carrier family 12 (potassium-chloride
           transporter), member 5 isoform 2 [Homo sapiens]
          Length = 1116

 Score = 32.3 bits (72), Expect = 2.0
 Identities = 35/136 (25%), Positives = 55/136 (40%), Gaps = 16/136 (11%)

Query: 730 GSEADRQRA---GTVTGLAVNIAALLS------------VMLQPYMPTVSATIQAQLQLP 774
           G   D Q++   GT+  +A   A  +S            V+   +   V+  +       
Sbjct: 422 GDLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVVGTLAW 481

Query: 775 PPACSILLTNFLCTLPAGHQIGTVSP-LFQKLENDQIESLRQRFGGGQAKTSPKPAVVET 833
           P    I++ +F  T  AG Q  T +P L Q +  D I    Q FG G+A   P  A++ T
Sbjct: 482 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLLT 541

Query: 834 VTTAKPQQIQALMDEV 849
               +   + A +DEV
Sbjct: 542 ACICEIGILIASLDEV 557


>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo
           sapiens]
          Length = 1478

 Score = 32.3 bits (72), Expect = 2.0
 Identities = 49/189 (25%), Positives = 78/189 (41%), Gaps = 31/189 (16%)

Query: 83  QWLEWEATELQPA---LSAALYYLVVQGKKGEDVLGSVRRALTHIDHSLSRQNCPF---L 136
           Q LE E T+++      SA L  LV + +  ED   S+ R        L ++  P    L
Sbjct: 408 QALERERTKVEEVNRQQSAQLEQLVKELQLKEDARASLER--------LVKEMAPLQEEL 459

Query: 137 AGETESLADIVLWGALYPLLQDPAYLPEELSALHSWFQTLSTQEPCQRAAETVLKQQGVL 196
           +G+ +      LW  L  LL   +   EEL+ L         +E  Q+  E  L +Q V 
Sbjct: 460 SGKGQEADQ--LWRRLQELLAHTSSWEEELAELR--------REKKQQQEEKELLEQEVR 509

Query: 197 ALRPYLQKQPQPSPAEGRAVTNEPEEEELATLSEEEIAMAVTAWEKGLESLPPLRPQQNP 256
           +L   LQ          + V++  E+++     ++ ++  V   E+       L     P
Sbjct: 510 SLTRQLQFLETQLAQVSQHVSDLEEQKKQLIQDKDHLSQQVGMLER-------LAGPPGP 562

Query: 257 VLPVAGERN 265
            LPVAGE+N
Sbjct: 563 ELPVAGEKN 571


>gi|46852147 mitochondrial isoleucine tRNA synthetase [Homo sapiens]
          Length = 1012

 Score = 32.0 bits (71), Expect = 2.7
 Identities = 26/110 (23%), Positives = 51/110 (46%), Gaps = 16/110 (14%)

Query: 443 VVQSSQHLFLDLPKLEKRLEEWLGRT--LPGSDWTPNAQFITRS--WLRDGLKPRCITRD 498
           V+++S+  F+++  ++   +E L +   +PGS      + + R   W        CI+R 
Sbjct: 474 VIRASKQWFINITDIKTAAKELLKKVKFIPGSALNGMVEMMDRRPYW--------CISRQ 525

Query: 499 LKWGTPVPLEGFEDKVFYVWFDATIGYL--SITANYTDQWERWWKNPEQV 546
             WG P+P+   + K  Y+    T  ++   +  + +D W  W   PEQ+
Sbjct: 526 RVWGVPIPVFHHKTKDEYLINSQTTEHIVKLVEQHGSDIW--WTLPPEQL 573



 Score = 30.4 bits (67), Expect = 7.7
 Identities = 16/53 (30%), Positives = 26/53 (49%), Gaps = 1/53 (1%)

Query: 273 PYVNNVPHLGNIIGCVLSADVFARYSRLRQWNTLYLCGTDEYGTATETKALEE 325
           PY N  PH+G+ +  +L  D+  R+  +      ++ G D +G   E K L E
Sbjct: 116 PYANGDPHVGHALNKILK-DIANRFHMMNGSKIHFVPGWDCHGLPIEIKVLSE 167


>gi|167466164 glutathione S-transferase theta 1 [Homo sapiens]
          Length = 240

 Score = 31.2 bits (69), Expect = 4.5
 Identities = 46/183 (25%), Positives = 77/183 (42%), Gaps = 23/183 (12%)

Query: 47  KVPVLQLDSGNYLFSTSA-----ICRYFFLLSGWEQDDL-----TNQWLEWEATELQPAL 96
           KVP L+   G++  + S      + R + +   W   DL      +++L W+ T L+ + 
Sbjct: 53  KVPALK--DGDFTLTESVAILLYLTRKYKVPDYWYPQDLQARARVDEYLAWQHTTLRRSC 110

Query: 97  SAALYYLVVQGK-KGEDVLGSVRRA-LTHIDHSLSR------QNCPFLAGETESLADIVL 148
             AL++ V+     GE V      A L  +D +L        QN  FL G   SLAD+V 
Sbjct: 111 LRALWHKVMFPVFLGEPVSPQTLAATLAELDVTLQLLEDKFLQNKAFLTGPHISLADLVA 170

Query: 149 WGALYPLLQDPAYLPEELSALHSWFQTLST---QEPCQRAAETVLKQQGVLALRPYLQKQ 205
              L   +     + E    L +W Q +     ++  Q A E +LK +      P ++++
Sbjct: 171 ITELMHPVGAGCQVFEGRPKLATWRQRVEAAVGEDLFQEAHEVILKAKDFPPADPTIKQK 230

Query: 206 PQP 208
             P
Sbjct: 231 LMP 233


>gi|194097352 actinin, alpha 1 isoform c [Homo sapiens]
          Length = 887

 Score = 31.2 bits (69), Expect = 4.5
 Identities = 15/42 (35%), Positives = 22/42 (52%), Gaps = 3/42 (7%)

Query: 436 KVCRSCPVVQSSQHLFLDLPKLEKRLEEWLGRTLPGSDWTPN 477
           ++C+   V Q ++ L  D  KL   L EW+ RT+P   W  N
Sbjct: 261 RICKVLAVNQENEQLMEDYEKLASDLLEWIRRTIP---WLEN 299


>gi|194097350 actinin, alpha 1 isoform a [Homo sapiens]
          Length = 914

 Score = 31.2 bits (69), Expect = 4.5
 Identities = 15/42 (35%), Positives = 22/42 (52%), Gaps = 3/42 (7%)

Query: 436 KVCRSCPVVQSSQHLFLDLPKLEKRLEEWLGRTLPGSDWTPN 477
           ++C+   V Q ++ L  D  KL   L EW+ RT+P   W  N
Sbjct: 261 RICKVLAVNQENEQLMEDYEKLASDLLEWIRRTIP---WLEN 299


>gi|4501891 actinin, alpha 1 isoform b [Homo sapiens]
          Length = 892

 Score = 31.2 bits (69), Expect = 4.5
 Identities = 15/42 (35%), Positives = 22/42 (52%), Gaps = 3/42 (7%)

Query: 436 KVCRSCPVVQSSQHLFLDLPKLEKRLEEWLGRTLPGSDWTPN 477
           ++C+   V Q ++ L  D  KL   L EW+ RT+P   W  N
Sbjct: 261 RICKVLAVNQENEQLMEDYEKLASDLLEWIRRTIP---WLEN 299


>gi|239755252 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 377

 Score = 30.8 bits (68), Expect = 5.9
 Identities = 34/115 (29%), Positives = 46/115 (40%), Gaps = 20/115 (17%)

Query: 421 CGKLINAV-ELKKPQCKVCRSCPVVQSSQHLFLDLPKLEKRLEEWLGRTLPGSDWTPNAQ 479
           C + +NA  EL  P   +CR             D    E RL +  G      +WT  A 
Sbjct: 233 CQEALNAERELCHPDTDLCR------------FDATDEELRLCQACGFEFDMCEWTSEAS 280

Query: 480 FITRSWLRDGLKPRCITRDLKWGTPVPLEGFEDKVFYVWFDATIGYLSITANYTD 534
               SW+R   K R I       TP   +G +D+ +YVW  A  G+   T N+ D
Sbjct: 281 AGQISWMRT--KAREIPAFES--TPQQDQGGDDEGYYVWVGAKHGF---TLNHLD 328


>gi|169201936 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 377

 Score = 30.8 bits (68), Expect = 5.9
 Identities = 34/115 (29%), Positives = 46/115 (40%), Gaps = 20/115 (17%)

Query: 421 CGKLINAV-ELKKPQCKVCRSCPVVQSSQHLFLDLPKLEKRLEEWLGRTLPGSDWTPNAQ 479
           C + +NA  EL  P   +CR             D    E RL +  G      +WT  A 
Sbjct: 233 CQEALNAERELCHPDTDLCR------------FDATDEELRLCQACGFEFDMCEWTSEAS 280

Query: 480 FITRSWLRDGLKPRCITRDLKWGTPVPLEGFEDKVFYVWFDATIGYLSITANYTD 534
               SW+R   K R I       TP   +G +D+ +YVW  A  G+   T N+ D
Sbjct: 281 AGQISWMRT--KAREIPAFES--TPQQDQGGDDEGYYVWVGAKHGF---TLNHLD 328


>gi|169191966 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 377

 Score = 30.8 bits (68), Expect = 5.9
 Identities = 34/115 (29%), Positives = 46/115 (40%), Gaps = 20/115 (17%)

Query: 421 CGKLINAV-ELKKPQCKVCRSCPVVQSSQHLFLDLPKLEKRLEEWLGRTLPGSDWTPNAQ 479
           C + +NA  EL  P   +CR             D    E RL +  G      +WT  A 
Sbjct: 233 CQEALNAERELCHPDTDLCR------------FDATDEELRLCQACGFEFDMCEWTSEAS 280

Query: 480 FITRSWLRDGLKPRCITRDLKWGTPVPLEGFEDKVFYVWFDATIGYLSITANYTD 534
               SW+R   K R I       TP   +G +D+ +YVW  A  G+   T N+ D
Sbjct: 281 AGQISWMRT--KAREIPAFES--TPQQDQGGDDEGYYVWVGAKHGF---TLNHLD 328


>gi|94721239 isoleucine tRNA synthetase [Homo sapiens]
          Length = 1262

 Score = 30.8 bits (68), Expect = 5.9
 Identities = 22/73 (30%), Positives = 37/73 (50%), Gaps = 9/73 (12%)

Query: 450 LFLDLPKLEKRLEEWLGRTLPGSD---WTPNAQFITR--SWLRDGLKPRCITRDLKWGTP 504
           ++  +P    R+E  + + L  +D   W P      R  +WL+D  +   I+R+  WGTP
Sbjct: 408 IYKAVPSWFVRVENMVDQLLRNNDLCYWVPELVREKRFGNWLKDA-RDWTISRNRYWGTP 466

Query: 505 VPL---EGFEDKV 514
           +PL   + FE+ V
Sbjct: 467 IPLWVSDDFEEVV 479


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,905,256
Number of Sequences: 37866
Number of extensions: 1663292
Number of successful extensions: 4987
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 4949
Number of HSP's gapped (non-prelim): 51
length of query: 900
length of database: 18,247,518
effective HSP length: 111
effective length of query: 789
effective length of database: 14,044,392
effective search space: 11081025288
effective search space used: 11081025288
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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