BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|14043022 methionyl-tRNA synthetase [Homo sapiens] (900 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|14043022 methionyl-tRNA synthetase [Homo sapiens] 1834 0.0 gi|24308436 methionine-tRNA synthetase 2 precursor [Homo sapiens] 126 8e-29 gi|62241042 glutamyl-prolyl tRNA synthetase [Homo sapiens] 47 8e-05 gi|5454158 valyl-tRNA synthetase [Homo sapiens] 43 0.002 gi|6996014 histidyl-tRNA synthetase [Homo sapiens] 40 0.007 gi|7661872 leucyl-tRNA synthetase 2, mitochondrial precursor [Ho... 38 0.037 gi|47419916 tryptophanyl-tRNA synthetase isoform a [Homo sapiens] 38 0.037 gi|47419914 tryptophanyl-tRNA synthetase isoform a [Homo sapiens] 38 0.037 gi|4503481 eukaryotic translation elongation factor 1 gamma [Hom... 38 0.048 gi|51873055 fibulin 2 isoform b precursor [Homo sapiens] 37 0.11 gi|51873053 fibulin 2 isoform a precursor [Homo sapiens] 37 0.11 gi|38488767 microtubule associated serine/threonine kinase famil... 34 0.54 gi|12025678 actinin, alpha 4 [Homo sapiens] 34 0.70 gi|30089948 protein phosphatase 1E [Homo sapiens] 33 0.91 gi|116256333 membrane metallo-endopeptidase [Homo sapiens] 33 1.2 gi|116256331 membrane metallo-endopeptidase [Homo sapiens] 33 1.2 gi|116256327 membrane metallo-endopeptidase [Homo sapiens] 33 1.2 gi|116256329 membrane metallo-endopeptidase [Homo sapiens] 33 1.2 gi|198041678 solute carrier family 12 (potassium-chloride transp... 32 2.0 gi|11968148 solute carrier family 12 (potassium-chloride transpo... 32 2.0 gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 32 2.0 gi|46852147 mitochondrial isoleucine tRNA synthetase [Homo sapiens] 32 2.7 gi|167466164 glutathione S-transferase theta 1 [Homo sapiens] 31 4.5 gi|194097352 actinin, alpha 1 isoform c [Homo sapiens] 31 4.5 gi|194097350 actinin, alpha 1 isoform a [Homo sapiens] 31 4.5 gi|4501891 actinin, alpha 1 isoform b [Homo sapiens] 31 4.5 gi|239755252 PREDICTED: hypothetical protein [Homo sapiens] 31 5.9 gi|169201936 PREDICTED: hypothetical protein [Homo sapiens] 31 5.9 gi|169191966 PREDICTED: hypothetical protein [Homo sapiens] 31 5.9 gi|94721239 isoleucine tRNA synthetase [Homo sapiens] 31 5.9 >gi|14043022 methionyl-tRNA synthetase [Homo sapiens] Length = 900 Score = 1834 bits (4751), Expect = 0.0 Identities = 900/900 (100%), Positives = 900/900 (100%) Query: 1 MRLFVSDGVPGCLPVLAAAGRARGRAEVLISTVGPEDCVVPFLTRPKVPVLQLDSGNYLF 60 MRLFVSDGVPGCLPVLAAAGRARGRAEVLISTVGPEDCVVPFLTRPKVPVLQLDSGNYLF Sbjct: 1 MRLFVSDGVPGCLPVLAAAGRARGRAEVLISTVGPEDCVVPFLTRPKVPVLQLDSGNYLF 60 Query: 61 STSAICRYFFLLSGWEQDDLTNQWLEWEATELQPALSAALYYLVVQGKKGEDVLGSVRRA 120 STSAICRYFFLLSGWEQDDLTNQWLEWEATELQPALSAALYYLVVQGKKGEDVLGSVRRA Sbjct: 61 STSAICRYFFLLSGWEQDDLTNQWLEWEATELQPALSAALYYLVVQGKKGEDVLGSVRRA 120 Query: 121 LTHIDHSLSRQNCPFLAGETESLADIVLWGALYPLLQDPAYLPEELSALHSWFQTLSTQE 180 LTHIDHSLSRQNCPFLAGETESLADIVLWGALYPLLQDPAYLPEELSALHSWFQTLSTQE Sbjct: 121 LTHIDHSLSRQNCPFLAGETESLADIVLWGALYPLLQDPAYLPEELSALHSWFQTLSTQE 180 Query: 181 PCQRAAETVLKQQGVLALRPYLQKQPQPSPAEGRAVTNEPEEEELATLSEEEIAMAVTAW 240 PCQRAAETVLKQQGVLALRPYLQKQPQPSPAEGRAVTNEPEEEELATLSEEEIAMAVTAW Sbjct: 181 PCQRAAETVLKQQGVLALRPYLQKQPQPSPAEGRAVTNEPEEEELATLSEEEIAMAVTAW 240 Query: 241 EKGLESLPPLRPQQNPVLPVAGERNVLITSALPYVNNVPHLGNIIGCVLSADVFARYSRL 300 EKGLESLPPLRPQQNPVLPVAGERNVLITSALPYVNNVPHLGNIIGCVLSADVFARYSRL Sbjct: 241 EKGLESLPPLRPQQNPVLPVAGERNVLITSALPYVNNVPHLGNIIGCVLSADVFARYSRL 300 Query: 301 RQWNTLYLCGTDEYGTATETKALEEGLTPQEICDKYHIIHADIYRWFNISFDIFGRTTTP 360 RQWNTLYLCGTDEYGTATETKALEEGLTPQEICDKYHIIHADIYRWFNISFDIFGRTTTP Sbjct: 301 RQWNTLYLCGTDEYGTATETKALEEGLTPQEICDKYHIIHADIYRWFNISFDIFGRTTTP 360 Query: 361 QQTKITQDIFQQLLKRGFVLQDTVEQLRCEHCARFLADRFVEGVCPFCGYEEARGDQCDK 420 QQTKITQDIFQQLLKRGFVLQDTVEQLRCEHCARFLADRFVEGVCPFCGYEEARGDQCDK Sbjct: 361 QQTKITQDIFQQLLKRGFVLQDTVEQLRCEHCARFLADRFVEGVCPFCGYEEARGDQCDK 420 Query: 421 CGKLINAVELKKPQCKVCRSCPVVQSSQHLFLDLPKLEKRLEEWLGRTLPGSDWTPNAQF 480 CGKLINAVELKKPQCKVCRSCPVVQSSQHLFLDLPKLEKRLEEWLGRTLPGSDWTPNAQF Sbjct: 421 CGKLINAVELKKPQCKVCRSCPVVQSSQHLFLDLPKLEKRLEEWLGRTLPGSDWTPNAQF 480 Query: 481 ITRSWLRDGLKPRCITRDLKWGTPVPLEGFEDKVFYVWFDATIGYLSITANYTDQWERWW 540 ITRSWLRDGLKPRCITRDLKWGTPVPLEGFEDKVFYVWFDATIGYLSITANYTDQWERWW Sbjct: 481 ITRSWLRDGLKPRCITRDLKWGTPVPLEGFEDKVFYVWFDATIGYLSITANYTDQWERWW 540 Query: 541 KNPEQVDLYQFMAKDNVPFHSLVFPCSALGAEDNYTLVSHLIATEYLNYEDGKFSKSRGV 600 KNPEQVDLYQFMAKDNVPFHSLVFPCSALGAEDNYTLVSHLIATEYLNYEDGKFSKSRGV Sbjct: 541 KNPEQVDLYQFMAKDNVPFHSLVFPCSALGAEDNYTLVSHLIATEYLNYEDGKFSKSRGV 600 Query: 601 GVFGDMAQDTGIPADIWRFYLLYIRPEGQDSAFSWTDLLLKNNSELLNNLGNFINRAGMF 660 GVFGDMAQDTGIPADIWRFYLLYIRPEGQDSAFSWTDLLLKNNSELLNNLGNFINRAGMF Sbjct: 601 GVFGDMAQDTGIPADIWRFYLLYIRPEGQDSAFSWTDLLLKNNSELLNNLGNFINRAGMF 660 Query: 661 VSKFFGGYVPEMVLTPDDQRLLAHVTLELQHYHQLLEKVRIRDALRSILTISRHGNQYIQ 720 VSKFFGGYVPEMVLTPDDQRLLAHVTLELQHYHQLLEKVRIRDALRSILTISRHGNQYIQ Sbjct: 661 VSKFFGGYVPEMVLTPDDQRLLAHVTLELQHYHQLLEKVRIRDALRSILTISRHGNQYIQ 720 Query: 721 VNEPWKRIKGSEADRQRAGTVTGLAVNIAALLSVMLQPYMPTVSATIQAQLQLPPPACSI 780 VNEPWKRIKGSEADRQRAGTVTGLAVNIAALLSVMLQPYMPTVSATIQAQLQLPPPACSI Sbjct: 721 VNEPWKRIKGSEADRQRAGTVTGLAVNIAALLSVMLQPYMPTVSATIQAQLQLPPPACSI 780 Query: 781 LLTNFLCTLPAGHQIGTVSPLFQKLENDQIESLRQRFGGGQAKTSPKPAVVETVTTAKPQ 840 LLTNFLCTLPAGHQIGTVSPLFQKLENDQIESLRQRFGGGQAKTSPKPAVVETVTTAKPQ Sbjct: 781 LLTNFLCTLPAGHQIGTVSPLFQKLENDQIESLRQRFGGGQAKTSPKPAVVETVTTAKPQ 840 Query: 841 QIQALMDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAVAEGKPPEAPKGKKKK 900 QIQALMDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAVAEGKPPEAPKGKKKK Sbjct: 841 QIQALMDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAVAEGKPPEAPKGKKKK 900 >gi|24308436 methionine-tRNA synthetase 2 precursor [Homo sapiens] Length = 593 Score = 126 bits (317), Expect = 8e-29 Identities = 129/524 (24%), Positives = 209/524 (39%), Gaps = 53/524 (10%) Query: 269 TSALPYVNNVPHLGNIIGCVLSADVFARYSRLRQWNTL---YLCGTDEYGTATETKALEE 325 T+ + YVN PH+G++ +L AD R+ RLR +T + GTDE+G + A Sbjct: 48 TTPIFYVNAAPHIGHLYSALL-ADALCRHRRLRGPSTAATRFSTGTDEHGLKIQQAAATA 106 Query: 326 GLTPQEICDKYHIIHADIYRWFNISFDIFGRTTTPQQTKITQDIFQQLLKRGFVLQDTVE 385 GL P E+CD+ +++ IS F RTT + Q + L RG + + E Sbjct: 107 GLAPTELCDRVSEQFQQLFQEAGISCTDFIRTTEARHRVAVQHFWGVLKSRGLLYKGVYE 166 Query: 386 QLRCEHCARFLADRFVEGVCPFCGYEEARGDQCDKCGKLINAVELKKPQCKVCRSCPVVQ 445 C FL + V GD + + V K + + R Sbjct: 167 GWYCASDECFLPEAKVTQ------QPGPSGDSFPVSLESGHPVSWTKEENYIFR------ 214 Query: 446 SSQHLFLDLPKLEKRLEEWLGRTLPGSDWTPNAQFITRSWLRDGLKPRCITR---DLKWG 502 L + K L+ WL R P + + WL + L ++R L WG Sbjct: 215 --------LSQFRKPLQRWL-RGNPQAITPEPFHHVVLQWLDEELPDLSVSRRSSHLHWG 265 Query: 503 TPVPLEGFEDKVFYVWFDATIGYLSITANYTDQWERWWKNPEQVDLYQFMAKDNVPFHSL 562 PVP G + + YVW DA + YL++ +++ WW + + KD + FH++ Sbjct: 266 IPVP--GDDSQTIYVWLDALVNYLTVIGYPNAEFKSWWPATSHI-----IGKDILKFHAI 318 Query: 563 VFPCSALGAEDNYTLVSHLIATEYLNYEDGKFSKSRGVGVFGDMAQDTGIPADIWRFYLL 622 +P LGA + + + K SKS G V D +R++LL Sbjct: 319 YWPAFLLGA--GMSPPQRICVHSHWTVCGQKMSKSLG-NVVDPRTCLNRYTVDGFRYFLL 375 Query: 623 YIRPEGQDSAFSWTDLLLKNNSELLNNLGNFINRAGM-----------FVSKFF----GG 667 D + ++ NSEL + LG +NR F + F G Sbjct: 376 RQGVPNWDCDYYDEKVVKLLNSELADALGGLLNRCTAKRINPSETYPAFCTTCFPSEPGL 435 Query: 668 YVPEMVLTPDDQRLLAHVTLELQHYHQLLEKVRIRDALRSILTISRHGNQYIQVNEPWKR 727 P + +D L++ V + + RI AL ++ + R N ++Q + PWK Sbjct: 436 VGPSVRAQAEDYALVSAVATLPKQVADHYDNFRIYKALEAVSSCVRQTNGFVQRHAPWKL 495 Query: 728 IKGSEADRQRAGTVTGLAVNIAALLSVMLQPYMPTVSATIQAQL 771 S D GTV +A+ + +LQP P+++ + ++L Sbjct: 496 NWESPVDAPWLGTVLHVALECLRVFGTLLQPVTPSLADKLLSRL 539 >gi|62241042 glutamyl-prolyl tRNA synthetase [Homo sapiens] Length = 1512 Score = 47.0 bits (110), Expect = 8e-05 Identities = 37/112 (33%), Positives = 54/112 (48%), Gaps = 8/112 (7%) Query: 786 LCTLPAGHQIGTVSPLFQKLENDQIESLRQRFGGGQAKTSPKPAVVETVTTAKPQQIQAL 845 L +P GH P E ++E+ + K P P++ TT++ + L Sbjct: 699 LIYIPDGHT--KEMPTSGSKEKTKVEATKNETSA-PFKERPTPSLNNNCTTSEDSLV--L 753 Query: 846 MDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLK---KQLAVAEGKPPEAP 894 + V QG++VRELKA+KA K +V A V +LL LK K+ E KP P Sbjct: 754 YNRVAVQGDVVRELKAKKAPKEDVDAAVKQLLSLKAEYKEKTGQEYKPGNPP 805 Score = 45.4 bits (106), Expect = 2e-04 Identities = 33/81 (40%), Positives = 44/81 (54%), Gaps = 13/81 (16%) Query: 827 KPAVVETVTTAKPQQIQALMDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLK---KQL 883 +PA +ET + + L D+V QG +VR+LK +KA K++V V +LL LK K L Sbjct: 892 EPAGLET------PEAKVLFDKVASQGEVVRKLKTEKAPKDQVDIAVQELLQLKAQYKSL 945 Query: 884 AVAEGKPPEA----PKGKKKK 900 E KP A K KKKK Sbjct: 946 IGVEYKPVSATGAEDKDKKKK 966 Score = 40.8 bits (94), Expect = 0.006 Identities = 22/59 (37%), Positives = 35/59 (59%) Query: 831 VETVTTAKPQQIQALMDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAVAEGK 889 + + ++A + ++L DEV QG +VR+LKA+K+ K ++ V LL LK Q GK Sbjct: 812 ISSNSSASILESKSLYDEVAAQGEVVRKLKAEKSPKAKINEAVECLLSLKAQYKEKTGK 870 >gi|5454158 valyl-tRNA synthetase [Homo sapiens] Length = 1264 Score = 42.7 bits (99), Expect = 0.002 Identities = 88/400 (22%), Positives = 150/400 (37%), Gaps = 77/400 (19%) Query: 17 AAAGRARGRAEVLISTVGPEDCVVPFLTRPKVPVLQLDSGN-YLFSTSAICRYFFLLS-- 73 A G G A I P PF P++P L+ G +++ +A+ + + Sbjct: 27 AGEGPGWGGAHPRICLQPPPTSRTPF-PPPRLPALEQGPGGLWVWGATAVAQLLWPAGLG 85 Query: 74 ---GWEQDDLTNQWLEWEATELQPALSAALYYLVVQGKKGED---VLGSVRRALTHIDHS 127 G L QW+ + TEL PA A + +D VLG++ RAL+ ++ Sbjct: 86 GPGGSRAAVLVQQWVSYADTELIPAACGATLPALGLRSSAQDPQAVLGALGRALSPLEEW 145 Query: 128 LSRQNCPFLAGETESLADIVLWGAL---YPLLQDPAYLPEELSALHSWFQTLSTQEPCQR 184 L +LAGE +LAD+ AL + + DP + + WF T Q + Sbjct: 146 LRLHT--YLAGEAPTLADLAAVTALLLPFRYVLDPP-ARRIWNNVTRWFVTCVRQPEFRA 202 Query: 185 AAETVLKQQGVLAL------------------------RPYLQK--------QPQPSPAE 212 V+ G L R L+K Q QP P E Sbjct: 203 VLGEVVLYSGARPLSHQPGPEAPALPKTAAQLKKEAKKREKLEKFQQKQKIQQQQPPPGE 262 Query: 213 GRAVTNEPEEEELATLS---------EEEIA----------MAVTAWEKGLESLPPLRPQ 253 + + E+ + ++ +++++ AW E +P+ Sbjct: 263 KKPKPEKREKRDPGVITYDLPTPPGEKKDVSGPMPDSYSPRYVEAAWYPWWEQQGFFKPE 322 Query: 254 Q-NPVLPVAGERNV-LITSALPYVNNVPHLGNIIGCVLSADVFARYSRLRQWNTLYLCGT 311 P + A R V ++ P V HLG+ + + D R+ R+R TL+ G Sbjct: 323 YGRPNVSAANPRGVFMMCIPPPNVTGSLHLGHALTNAIQ-DSLTRWHRMRGETTLWNPGC 381 Query: 312 DEYGTATET---KAL--EEGLTPQEICDKYHIIHADIYRW 346 D G AT+ K L E+GL+ ++ + + ++++W Sbjct: 382 DHAGIATQVVVEKKLWREQGLSRHQLGREAFL--QEVWKW 419 >gi|6996014 histidyl-tRNA synthetase [Homo sapiens] Length = 509 Score = 40.4 bits (93), Expect = 0.007 Identities = 27/60 (45%), Positives = 34/60 (56%), Gaps = 4/60 (6%) Query: 843 QALMDEVTK-QGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAVAEGKPP---EAPKGKK 898 +A ++E+ K QG VR LK QKA + EVAKLL LK QL E K + PKG + Sbjct: 4 RAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPKGTR 63 >gi|7661872 leucyl-tRNA synthetase 2, mitochondrial precursor [Homo sapiens] Length = 903 Score = 38.1 bits (87), Expect = 0.037 Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 3/116 (2%) Query: 268 ITSALPYVNNVPHLGNIIGCVLSADVFARYSRLRQWNTLYLCGTDEYGTATETKALEEGL 327 + S PY + H+G++ +S D AR+ ++R + G D +G E A+E L Sbjct: 86 VLSMFPYPSGKLHMGHVRVYTIS-DTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNL 144 Query: 328 TPQEICDK--YHIIHADIYRWFNISFDIFGRTTTPQQTKITQDIFQQLLKRGFVLQ 381 PQ H+ S+D T P K TQ +F +L + G Q Sbjct: 145 HPQSWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQ 200 >gi|47419916 tryptophanyl-tRNA synthetase isoform a [Homo sapiens] Length = 471 Score = 38.1 bits (87), Expect = 0.037 Identities = 19/57 (33%), Positives = 31/57 (54%) Query: 837 AKPQQIQALMDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAVAEGKPPEA 893 ++P + L + + QG +VR LKA A K+E+ + V L+ LK A G+ +A Sbjct: 4 SEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA 60 >gi|47419914 tryptophanyl-tRNA synthetase isoform a [Homo sapiens] Length = 471 Score = 38.1 bits (87), Expect = 0.037 Identities = 19/57 (33%), Positives = 31/57 (54%) Query: 837 AKPQQIQALMDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAVAEGKPPEA 893 ++P + L + + QG +VR LKA A K+E+ + V L+ LK A G+ +A Sbjct: 4 SEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA 60 >gi|4503481 eukaryotic translation elongation factor 1 gamma [Homo sapiens] Length = 437 Score = 37.7 bits (86), Expect = 0.048 Identities = 49/205 (23%), Positives = 86/205 (41%), Gaps = 20/205 (9%) Query: 47 KVPVLQLDSGNYLFSTSAICRYF----FLLSGWEQDDLTNQWLEWEATELQPALSAALY- 101 KVP + D G +F ++AI Y S E QW+ + +++ P S ++ Sbjct: 57 KVPAFEGDDGFCVFESNAIAYYVSNEELRGSTPEAAAQVVQWVSFADSDIVPPASTWVFP 116 Query: 102 --YLVVQGKKG-EDVLGSVRRALTHIDHSLSRQNCPFLAGETESLADI-----VLWGALY 153 ++ K+ E+ VRR L +D L + FL GE +LADI +LW LY Sbjct: 117 TLGIMHHNKQATENAKEEVRRILGLLDAYLKTRT--FLVGERVTLADITVVCTLLW--LY 172 Query: 154 PLLQDPAYLPEELSALHSWFQTLSTQEPCQRAAETV--LKQQGVLALRPYLQKQPQPSPA 211 + +P++ + + WF T Q + V ++ + + + QP+ Sbjct: 173 KQVLEPSF-RQAFPNTNRWFLTCINQPQFRAVLGEVKLCEKMAQFDAKKFAETQPKKDTP 231 Query: 212 EGRAVTNEPEEEELATLSEEEIAMA 236 + E +++ A EE+ A A Sbjct: 232 RKEKGSREEKQKPQAERKEEKKAAA 256 >gi|51873055 fibulin 2 isoform b precursor [Homo sapiens] Length = 1184 Score = 36.6 bits (83), Expect = 0.11 Identities = 23/62 (37%), Positives = 30/62 (48%), Gaps = 4/62 (6%) Query: 206 PQPSPAEGRAVTNEPEEEELATLSEEEIAMA---VTAWEKGLESLPPLRPQQNPVLPVAG 262 P P A+ R VT + EEEE EE+A+ +GL+ LP P P LP+ Sbjct: 263 PAPVQAKARRVTEDSEEEEEEEEEREEMAVTEQLAAGGHRGLDGLPTTAP-AGPSLPIQE 321 Query: 263 ER 264 ER Sbjct: 322 ER 323 >gi|51873053 fibulin 2 isoform a precursor [Homo sapiens] Length = 1231 Score = 36.6 bits (83), Expect = 0.11 Identities = 23/62 (37%), Positives = 30/62 (48%), Gaps = 4/62 (6%) Query: 206 PQPSPAEGRAVTNEPEEEELATLSEEEIAMA---VTAWEKGLESLPPLRPQQNPVLPVAG 262 P P A+ R VT + EEEE EE+A+ +GL+ LP P P LP+ Sbjct: 263 PAPVQAKARRVTEDSEEEEEEEEEREEMAVTEQLAAGGHRGLDGLPTTAP-AGPSLPIQE 321 Query: 263 ER 264 ER Sbjct: 322 ER 323 >gi|38488767 microtubule associated serine/threonine kinase family member 4 isoform b [Homo sapiens] Length = 250 Score = 34.3 bits (77), Expect = 0.54 Identities = 19/51 (37%), Positives = 27/51 (52%) Query: 175 TLSTQEPCQRAAETVLKQQGVLALRPYLQKQPQPSPAEGRAVTNEPEEEEL 225 TL + P A +VL ++GVLAL P L P G + + E ++EEL Sbjct: 72 TLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEEL 122 >gi|12025678 actinin, alpha 4 [Homo sapiens] Length = 911 Score = 33.9 bits (76), Expect = 0.70 Identities = 14/35 (40%), Positives = 21/35 (60%) Query: 436 KVCRSCPVVQSSQHLFLDLPKLEKRLEEWLGRTLP 470 ++C+ V Q ++HL D KL L EW+ RT+P Sbjct: 280 RICKVLAVNQENEHLMEDYEKLASDLLEWIRRTIP 314 >gi|30089948 protein phosphatase 1E [Homo sapiens] Length = 755 Score = 33.5 bits (75), Expect = 0.91 Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 18/84 (21%) Query: 177 STQEPCQRAAETVLKQQGVLALRPYLQKQPQPSPAEGRAVTNEPEEEELATLSEEEIAMA 236 S +EP + AA ++G ++ P P E AV E EEE AT Sbjct: 62 SVEEPGEEAATVAATEEG--------DQEQDPEPEEEAAVEGEEEEEGAAT--------- 104 Query: 237 VTAWEKGLESLPPLRPQQNPVLPV 260 A G ++PP PQ P+ P+ Sbjct: 105 -AAAAPGHSAVPPPPPQLPPLPPL 127 >gi|116256333 membrane metallo-endopeptidase [Homo sapiens] Length = 750 Score = 33.1 bits (74), Expect = 1.2 Identities = 14/49 (28%), Positives = 31/49 (63%) Query: 844 ALMDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAVAEGKPPE 892 A +D + ++R+ + D+N++A E+ K+++L+K++A A KP + Sbjct: 244 AYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPED 292 >gi|116256331 membrane metallo-endopeptidase [Homo sapiens] Length = 750 Score = 33.1 bits (74), Expect = 1.2 Identities = 14/49 (28%), Positives = 31/49 (63%) Query: 844 ALMDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAVAEGKPPE 892 A +D + ++R+ + D+N++A E+ K+++L+K++A A KP + Sbjct: 244 AYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPED 292 >gi|116256327 membrane metallo-endopeptidase [Homo sapiens] Length = 750 Score = 33.1 bits (74), Expect = 1.2 Identities = 14/49 (28%), Positives = 31/49 (63%) Query: 844 ALMDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAVAEGKPPE 892 A +D + ++R+ + D+N++A E+ K+++L+K++A A KP + Sbjct: 244 AYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPED 292 >gi|116256329 membrane metallo-endopeptidase [Homo sapiens] Length = 750 Score = 33.1 bits (74), Expect = 1.2 Identities = 14/49 (28%), Positives = 31/49 (63%) Query: 844 ALMDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAVAEGKPPE 892 A +D + ++R+ + D+N++A E+ K+++L+K++A A KP + Sbjct: 244 AYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPED 292 >gi|198041678 solute carrier family 12 (potassium-chloride transporter), member 5 isoform 1 [Homo sapiens] Length = 1139 Score = 32.3 bits (72), Expect = 2.0 Identities = 35/136 (25%), Positives = 55/136 (40%), Gaps = 16/136 (11%) Query: 730 GSEADRQRA---GTVTGLAVNIAALLS------------VMLQPYMPTVSATIQAQLQLP 774 G D Q++ GT+ +A A +S V+ + V+ + Sbjct: 445 GDLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVVGTLAW 504 Query: 775 PPACSILLTNFLCTLPAGHQIGTVSP-LFQKLENDQIESLRQRFGGGQAKTSPKPAVVET 833 P I++ +F T AG Q T +P L Q + D I Q FG G+A P A++ T Sbjct: 505 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLLT 564 Query: 834 VTTAKPQQIQALMDEV 849 + + A +DEV Sbjct: 565 ACICEIGILIASLDEV 580 >gi|11968148 solute carrier family 12 (potassium-chloride transporter), member 5 isoform 2 [Homo sapiens] Length = 1116 Score = 32.3 bits (72), Expect = 2.0 Identities = 35/136 (25%), Positives = 55/136 (40%), Gaps = 16/136 (11%) Query: 730 GSEADRQRA---GTVTGLAVNIAALLS------------VMLQPYMPTVSATIQAQLQLP 774 G D Q++ GT+ +A A +S V+ + V+ + Sbjct: 422 GDLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVVGTLAW 481 Query: 775 PPACSILLTNFLCTLPAGHQIGTVSP-LFQKLENDQIESLRQRFGGGQAKTSPKPAVVET 833 P I++ +F T AG Q T +P L Q + D I Q FG G+A P A++ T Sbjct: 482 PSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLLT 541 Query: 834 VTTAKPQQIQALMDEV 849 + + A +DEV Sbjct: 542 ACICEIGILIASLDEV 557 >gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapiens] Length = 1478 Score = 32.3 bits (72), Expect = 2.0 Identities = 49/189 (25%), Positives = 78/189 (41%), Gaps = 31/189 (16%) Query: 83 QWLEWEATELQPA---LSAALYYLVVQGKKGEDVLGSVRRALTHIDHSLSRQNCPF---L 136 Q LE E T+++ SA L LV + + ED S+ R L ++ P L Sbjct: 408 QALERERTKVEEVNRQQSAQLEQLVKELQLKEDARASLER--------LVKEMAPLQEEL 459 Query: 137 AGETESLADIVLWGALYPLLQDPAYLPEELSALHSWFQTLSTQEPCQRAAETVLKQQGVL 196 +G+ + LW L LL + EEL+ L +E Q+ E L +Q V Sbjct: 460 SGKGQEADQ--LWRRLQELLAHTSSWEEELAELR--------REKKQQQEEKELLEQEVR 509 Query: 197 ALRPYLQKQPQPSPAEGRAVTNEPEEEELATLSEEEIAMAVTAWEKGLESLPPLRPQQNP 256 +L LQ + V++ E+++ ++ ++ V E+ L P Sbjct: 510 SLTRQLQFLETQLAQVSQHVSDLEEQKKQLIQDKDHLSQQVGMLER-------LAGPPGP 562 Query: 257 VLPVAGERN 265 LPVAGE+N Sbjct: 563 ELPVAGEKN 571 >gi|46852147 mitochondrial isoleucine tRNA synthetase [Homo sapiens] Length = 1012 Score = 32.0 bits (71), Expect = 2.7 Identities = 26/110 (23%), Positives = 51/110 (46%), Gaps = 16/110 (14%) Query: 443 VVQSSQHLFLDLPKLEKRLEEWLGRT--LPGSDWTPNAQFITRS--WLRDGLKPRCITRD 498 V+++S+ F+++ ++ +E L + +PGS + + R W CI+R Sbjct: 474 VIRASKQWFINITDIKTAAKELLKKVKFIPGSALNGMVEMMDRRPYW--------CISRQ 525 Query: 499 LKWGTPVPLEGFEDKVFYVWFDATIGYL--SITANYTDQWERWWKNPEQV 546 WG P+P+ + K Y+ T ++ + + +D W W PEQ+ Sbjct: 526 RVWGVPIPVFHHKTKDEYLINSQTTEHIVKLVEQHGSDIW--WTLPPEQL 573 Score = 30.4 bits (67), Expect = 7.7 Identities = 16/53 (30%), Positives = 26/53 (49%), Gaps = 1/53 (1%) Query: 273 PYVNNVPHLGNIIGCVLSADVFARYSRLRQWNTLYLCGTDEYGTATETKALEE 325 PY N PH+G+ + +L D+ R+ + ++ G D +G E K L E Sbjct: 116 PYANGDPHVGHALNKILK-DIANRFHMMNGSKIHFVPGWDCHGLPIEIKVLSE 167 >gi|167466164 glutathione S-transferase theta 1 [Homo sapiens] Length = 240 Score = 31.2 bits (69), Expect = 4.5 Identities = 46/183 (25%), Positives = 77/183 (42%), Gaps = 23/183 (12%) Query: 47 KVPVLQLDSGNYLFSTSA-----ICRYFFLLSGWEQDDL-----TNQWLEWEATELQPAL 96 KVP L+ G++ + S + R + + W DL +++L W+ T L+ + Sbjct: 53 KVPALK--DGDFTLTESVAILLYLTRKYKVPDYWYPQDLQARARVDEYLAWQHTTLRRSC 110 Query: 97 SAALYYLVVQGK-KGEDVLGSVRRA-LTHIDHSLSR------QNCPFLAGETESLADIVL 148 AL++ V+ GE V A L +D +L QN FL G SLAD+V Sbjct: 111 LRALWHKVMFPVFLGEPVSPQTLAATLAELDVTLQLLEDKFLQNKAFLTGPHISLADLVA 170 Query: 149 WGALYPLLQDPAYLPEELSALHSWFQTLST---QEPCQRAAETVLKQQGVLALRPYLQKQ 205 L + + E L +W Q + ++ Q A E +LK + P ++++ Sbjct: 171 ITELMHPVGAGCQVFEGRPKLATWRQRVEAAVGEDLFQEAHEVILKAKDFPPADPTIKQK 230 Query: 206 PQP 208 P Sbjct: 231 LMP 233 >gi|194097352 actinin, alpha 1 isoform c [Homo sapiens] Length = 887 Score = 31.2 bits (69), Expect = 4.5 Identities = 15/42 (35%), Positives = 22/42 (52%), Gaps = 3/42 (7%) Query: 436 KVCRSCPVVQSSQHLFLDLPKLEKRLEEWLGRTLPGSDWTPN 477 ++C+ V Q ++ L D KL L EW+ RT+P W N Sbjct: 261 RICKVLAVNQENEQLMEDYEKLASDLLEWIRRTIP---WLEN 299 >gi|194097350 actinin, alpha 1 isoform a [Homo sapiens] Length = 914 Score = 31.2 bits (69), Expect = 4.5 Identities = 15/42 (35%), Positives = 22/42 (52%), Gaps = 3/42 (7%) Query: 436 KVCRSCPVVQSSQHLFLDLPKLEKRLEEWLGRTLPGSDWTPN 477 ++C+ V Q ++ L D KL L EW+ RT+P W N Sbjct: 261 RICKVLAVNQENEQLMEDYEKLASDLLEWIRRTIP---WLEN 299 >gi|4501891 actinin, alpha 1 isoform b [Homo sapiens] Length = 892 Score = 31.2 bits (69), Expect = 4.5 Identities = 15/42 (35%), Positives = 22/42 (52%), Gaps = 3/42 (7%) Query: 436 KVCRSCPVVQSSQHLFLDLPKLEKRLEEWLGRTLPGSDWTPN 477 ++C+ V Q ++ L D KL L EW+ RT+P W N Sbjct: 261 RICKVLAVNQENEQLMEDYEKLASDLLEWIRRTIP---WLEN 299 >gi|239755252 PREDICTED: hypothetical protein [Homo sapiens] Length = 377 Score = 30.8 bits (68), Expect = 5.9 Identities = 34/115 (29%), Positives = 46/115 (40%), Gaps = 20/115 (17%) Query: 421 CGKLINAV-ELKKPQCKVCRSCPVVQSSQHLFLDLPKLEKRLEEWLGRTLPGSDWTPNAQ 479 C + +NA EL P +CR D E RL + G +WT A Sbjct: 233 CQEALNAERELCHPDTDLCR------------FDATDEELRLCQACGFEFDMCEWTSEAS 280 Query: 480 FITRSWLRDGLKPRCITRDLKWGTPVPLEGFEDKVFYVWFDATIGYLSITANYTD 534 SW+R K R I TP +G +D+ +YVW A G+ T N+ D Sbjct: 281 AGQISWMRT--KAREIPAFES--TPQQDQGGDDEGYYVWVGAKHGF---TLNHLD 328 >gi|169201936 PREDICTED: hypothetical protein [Homo sapiens] Length = 377 Score = 30.8 bits (68), Expect = 5.9 Identities = 34/115 (29%), Positives = 46/115 (40%), Gaps = 20/115 (17%) Query: 421 CGKLINAV-ELKKPQCKVCRSCPVVQSSQHLFLDLPKLEKRLEEWLGRTLPGSDWTPNAQ 479 C + +NA EL P +CR D E RL + G +WT A Sbjct: 233 CQEALNAERELCHPDTDLCR------------FDATDEELRLCQACGFEFDMCEWTSEAS 280 Query: 480 FITRSWLRDGLKPRCITRDLKWGTPVPLEGFEDKVFYVWFDATIGYLSITANYTD 534 SW+R K R I TP +G +D+ +YVW A G+ T N+ D Sbjct: 281 AGQISWMRT--KAREIPAFES--TPQQDQGGDDEGYYVWVGAKHGF---TLNHLD 328 >gi|169191966 PREDICTED: hypothetical protein [Homo sapiens] Length = 377 Score = 30.8 bits (68), Expect = 5.9 Identities = 34/115 (29%), Positives = 46/115 (40%), Gaps = 20/115 (17%) Query: 421 CGKLINAV-ELKKPQCKVCRSCPVVQSSQHLFLDLPKLEKRLEEWLGRTLPGSDWTPNAQ 479 C + +NA EL P +CR D E RL + G +WT A Sbjct: 233 CQEALNAERELCHPDTDLCR------------FDATDEELRLCQACGFEFDMCEWTSEAS 280 Query: 480 FITRSWLRDGLKPRCITRDLKWGTPVPLEGFEDKVFYVWFDATIGYLSITANYTD 534 SW+R K R I TP +G +D+ +YVW A G+ T N+ D Sbjct: 281 AGQISWMRT--KAREIPAFES--TPQQDQGGDDEGYYVWVGAKHGF---TLNHLD 328 >gi|94721239 isoleucine tRNA synthetase [Homo sapiens] Length = 1262 Score = 30.8 bits (68), Expect = 5.9 Identities = 22/73 (30%), Positives = 37/73 (50%), Gaps = 9/73 (12%) Query: 450 LFLDLPKLEKRLEEWLGRTLPGSD---WTPNAQFITR--SWLRDGLKPRCITRDLKWGTP 504 ++ +P R+E + + L +D W P R +WL+D + I+R+ WGTP Sbjct: 408 IYKAVPSWFVRVENMVDQLLRNNDLCYWVPELVREKRFGNWLKDA-RDWTISRNRYWGTP 466 Query: 505 VPL---EGFEDKV 514 +PL + FE+ V Sbjct: 467 IPLWVSDDFEEVV 479 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.136 0.418 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 35,905,256 Number of Sequences: 37866 Number of extensions: 1663292 Number of successful extensions: 4987 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 16 Number of HSP's successfully gapped in prelim test: 17 Number of HSP's that attempted gapping in prelim test: 4949 Number of HSP's gapped (non-prelim): 51 length of query: 900 length of database: 18,247,518 effective HSP length: 111 effective length of query: 789 effective length of database: 14,044,392 effective search space: 11081025288 effective search space used: 11081025288 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.