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Search of human proteins with 7661880
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7661880 centaurin beta1 [Homo sapiens]
(740 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7661880 centaurin beta1 [Homo sapiens] 1479 0.0
gi|187608516 centaurin, beta 2 [Homo sapiens] 736 0.0
gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH doma... 605 e-173
gi|206597522 ArfGAP with SH3 domain, ankyrin repeat and PH domai... 177 4e-44
gi|4502249 ArfGAP with SH3 domain, ankyrin repeat and PH domain ... 177 4e-44
gi|19923540 ArfGAP with SH3 domain, ankyrin repeat and PH domain... 174 3e-43
gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domai... 171 3e-42
gi|46094081 development and differentiation enhancing factor 1 [... 165 1e-40
gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens] 149 9e-36
gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH do... 131 3e-30
gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activat... 130 6e-30
gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens] 129 7e-30
gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens] 129 7e-30
gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens] 129 7e-30
gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH do... 129 7e-30
gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repea... 126 6e-29
gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repea... 126 6e-29
gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH do... 126 6e-29
gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH do... 126 8e-29
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens] 116 7e-26
gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens] 116 7e-26
gi|23943872 small ArfGAP2 [Homo sapiens] 100 5e-21
gi|6806913 centaurin, alpha 1 [Homo sapiens] 96 1e-19
gi|208022687 GTPase regulator associated with the focal adhesion... 93 8e-19
gi|7662208 GTPase regulator associated with the focal adhesion k... 93 8e-19
gi|21264558 stromal membrane-associated GTPase-activating protei... 93 8e-19
gi|21264592 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom... 91 3e-18
gi|113204622 stromal membrane-associated GTPase-activating prote... 91 3e-18
gi|206725422 G protein-coupled receptor kinase interacting ArfGA... 88 3e-17
gi|21237786 G protein-coupled receptor kinase interacting ArfGAP... 88 3e-17
>gi|7661880 centaurin beta1 [Homo sapiens]
Length = 740
Score = 1479 bits (3829), Expect = 0.0
Identities = 740/740 (100%), Positives = 740/740 (100%)
Query: 1 MTVKLDFEECLKDSPRFRASIELVEAEVSELETRLEKLLKLGTGLLESGRHYLAASRAFV 60
MTVKLDFEECLKDSPRFRASIELVEAEVSELETRLEKLLKLGTGLLESGRHYLAASRAFV
Sbjct: 1 MTVKLDFEECLKDSPRFRASIELVEAEVSELETRLEKLLKLGTGLLESGRHYLAASRAFV 60
Query: 61 VGICDLARLGPPEPMMAECLEKFTVSLNHKLDSHAELLDATQHTLQQQIQTLVKEGLRGF 120
VGICDLARLGPPEPMMAECLEKFTVSLNHKLDSHAELLDATQHTLQQQIQTLVKEGLRGF
Sbjct: 61 VGICDLARLGPPEPMMAECLEKFTVSLNHKLDSHAELLDATQHTLQQQIQTLVKEGLRGF 120
Query: 121 REARRDFWRGAESLEAALTHNAEVPRRRAQEAEEAGAALRTARAGYRGRALDYALQINVI 180
REARRDFWRGAESLEAALTHNAEVPRRRAQEAEEAGAALRTARAGYRGRALDYALQINVI
Sbjct: 121 REARRDFWRGAESLEAALTHNAEVPRRRAQEAEEAGAALRTARAGYRGRALDYALQINVI 180
Query: 181 EDKRKFDIMEFVLRLVEAQATHFQQGHEELSRLSQYRKELGAQLHQLVLNSAREKRDMEQ 240
EDKRKFDIMEFVLRLVEAQATHFQQGHEELSRLSQYRKELGAQLHQLVLNSAREKRDMEQ
Sbjct: 181 EDKRKFDIMEFVLRLVEAQATHFQQGHEELSRLSQYRKELGAQLHQLVLNSAREKRDMEQ 240
Query: 241 RHVLLKQKELGGEEPEPSLREGPGGLVMEGHLFKRASNAFKTWSRRWFTIQSNQLVYQKK 300
RHVLLKQKELGGEEPEPSLREGPGGLVMEGHLFKRASNAFKTWSRRWFTIQSNQLVYQKK
Sbjct: 241 RHVLLKQKELGGEEPEPSLREGPGGLVMEGHLFKRASNAFKTWSRRWFTIQSNQLVYQKK 300
Query: 301 YKDPVTVVVDDLRLCTVKLCPDSERRFCFEVVSTSKSCLLQADSERLLQLWVSAVQSSIA 360
YKDPVTVVVDDLRLCTVKLCPDSERRFCFEVVSTSKSCLLQADSERLLQLWVSAVQSSIA
Sbjct: 301 YKDPVTVVVDDLRLCTVKLCPDSERRFCFEVVSTSKSCLLQADSERLLQLWVSAVQSSIA 360
Query: 361 SAFSQARLDDSPRGPGQGSGHLAIGSAATLGSGGMARGREPGGVGHVVAQVQSVDGNAQC 420
SAFSQARLDDSPRGPGQGSGHLAIGSAATLGSGGMARGREPGGVGHVVAQVQSVDGNAQC
Sbjct: 361 SAFSQARLDDSPRGPGQGSGHLAIGSAATLGSGGMARGREPGGVGHVVAQVQSVDGNAQC 420
Query: 421 CDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWEPELVKLMCELGNVI 480
CDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWEPELVKLMCELGNVI
Sbjct: 421 CDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWEPELVKLMCELGNVI 480
Query: 481 INQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLTKLPEIRGRRGGRGRPRGQP 540
INQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLTKLPEIRGRRGGRGRPRGQP
Sbjct: 481 INQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLTKLPEIRGRRGGRGRPRGQP 540
Query: 541 PVPPKPSIRPRPGSLRSKPEPPSEDLGSLHPGALLFRASGHPPSLPTMADALAHGADVNW 600
PVPPKPSIRPRPGSLRSKPEPPSEDLGSLHPGALLFRASGHPPSLPTMADALAHGADVNW
Sbjct: 541 PVPPKPSIRPRPGSLRSKPEPPSEDLGSLHPGALLFRASGHPPSLPTMADALAHGADVNW 600
Query: 601 VNGGQDNATPLIQATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILGHTGLACLFL 660
VNGGQDNATPLIQATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILGHTGLACLFL
Sbjct: 601 VNGGQDNATPLIQATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILGHTGLACLFL 660
Query: 661 KRGADLGARDSEGRDPLTIAMETANADIVTLLRLAKMREAEAAQGQAGDETYLDIFRDFS 720
KRGADLGARDSEGRDPLTIAMETANADIVTLLRLAKMREAEAAQGQAGDETYLDIFRDFS
Sbjct: 661 KRGADLGARDSEGRDPLTIAMETANADIVTLLRLAKMREAEAAQGQAGDETYLDIFRDFS 720
Query: 721 LMASDDPEKLSRRSHDLHTL 740
LMASDDPEKLSRRSHDLHTL
Sbjct: 721 LMASDDPEKLSRRSHDLHTL 740
>gi|187608516 centaurin, beta 2 [Homo sapiens]
Length = 778
Score = 736 bits (1900), Expect = 0.0
Identities = 403/783 (51%), Positives = 525/783 (67%), Gaps = 56/783 (7%)
Query: 1 MTVKLDFEECLKDSPRFRASIELVEAEVSELETRLEKLLKLGTGLLESGRHYLAASRAFV 60
M + +DFEECLKDSPRFRA++E VE +V+ELE +L+KL+KL ++++G+ + A++ F+
Sbjct: 1 MKMTVDFEECLKDSPRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCVANKQFM 60
Query: 61 VGICDLARLGPPEPMMAECLEKFTVSLNHKLDSHAELLDATQHTLQQQIQTLVKEGLRGF 120
GI DLA+ + ++ L KF+ SL ++ H L D TQ +++ Q+Q VKE LR F
Sbjct: 61 NGIRDLAQYSSNDAVVETSLTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKEDLRKF 120
Query: 121 REARRDFWRGAESLEAALTHNAEVPRRRAQEAEEAGAALRTARAGYRGRALDYALQINVI 180
++A++ F + +E E AL NA+V R + E EEA L R +R ALDY LQINV+
Sbjct: 121 KDAKKQFEKVSEEKENALVKNAQVQRNKQHEVEEATNILTATRKCFRHIALDYVLQINVL 180
Query: 181 EDKRKFDIMEFVLRLVEAQATHFQQGHEELSRLSQYRKELGAQLHQLVLNSAREKRDMEQ 240
+ KR+ +I++ +L + A F QG++ S L Y K+LGAQL +LV+++A+EKR+MEQ
Sbjct: 181 QSKRRSEILKSMLSFMYAHLAFFHQGYDLFSELGPYMKDLGAQLDRLVVDAAKEKREMEQ 240
Query: 241 RHVLLKQKELGGEEPEPSLR-EGPGGLVMEGHLFKRASNAFKTWSRRWFTIQSNQLVYQK 299
+H ++QK+ ++ + + G+VMEG+LFKRASNAFKTW+RRWF+IQ+NQLVYQK
Sbjct: 241 KHSTIQQKDFSSDDSKLEYNVDAANGIVMEGYLFKRASNAFKTWNRRWFSIQNNQLVYQK 300
Query: 300 KYKDPVTVVVDDLRLCTVKLCPDSERRFCFEVVSTSKSCLLQADSERLLQLWVSAVQSSI 359
K+KD TVVV+DLRLCTVK C D ERRFCFEVVS +KSC+LQADSE+L Q W+ AVQ+SI
Sbjct: 301 KFKDNPTVVVEDLRLCTVKHCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSI 360
Query: 360 ASAFSQARLDDSPRGPGQGSGHLAIGSAATLGSGGMARGREPGGVGHVVAQVQSVDGNAQ 419
A+A+ + + D+S + + S S +L SG ++ + G + +VQ + GNA
Sbjct: 361 ATAYRE-KGDESEKLDKKSSP-----STGSLDSGNESKEKLLKGES-ALQRVQCIPGNAS 413
Query: 420 CCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWEPELVKLMCELGNV 479
CCDC P WASINLG+TLCI+CSGIHRSLGVHFSKVRSLTLD+WEPEL+KLMCELGN
Sbjct: 414 CCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMCELGND 473
Query: 480 IINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVE-----------------KKFLTK 522
+IN++YEA VE M +KKP P RQEKEA+I AKYVE KKF++K
Sbjct: 474 VINRVYEANVEKMGIKKPQPG-QRQEKEAYIRAKYVERKFVDKYSISLSPPEQQKKFVSK 532
Query: 523 LPEIRGRRGGRGRPRGQPPVPPKPSIR-----------------PRPGSLRSKPEPPSE- 564
E + + P Q + S+R P S S EP E
Sbjct: 533 SSEEKRLSISKFGPGDQVRASAQSSVRSNDSGIQQSSDDGRESLPSTVSANSLYEPEGER 592
Query: 565 -------DLGSLHPGALLFRASGHPPSLPTMADALAHGADVNWVNGGQDNATPLIQATAA 617
D L+PG L+RAS + +LP MA+ALAHGADVNW N ++ ATPLIQA
Sbjct: 593 QDSSMFLDSKHLNPGLQLYRAS-YEKNLPKMAEALAHGADVNWANSEENKATPLIQAVLG 651
Query: 618 NSLLACEFLLQNGANVNQADSAGRGPLHHATILGHTGLACLFLKRGADLGARDSEGRDPL 677
SL+ CEFLLQNGANVNQ D GRGPLHHAT+LGHTG CLFLKRGA+ A D EG+DPL
Sbjct: 652 GSLVTCEFLLQNGANVNQRDVQGRGPLHHATVLGHTGQVCLFLKRGANQHATDEEGKDPL 711
Query: 678 TIAMETANADIVTLLRLAK----MREAEAAQGQAGDETYLDIFRDFSLMASDDPEKLSRR 733
+IA+E ANADIVTLLRLA+ MRE+E GQ GDETY DIFRDFS MAS++PEKL+R
Sbjct: 712 SIAVEAANADIVTLLRLARMNEEMRESEGLYGQPGDETYQDIFRDFSQMASNNPEKLNRF 771
Query: 734 SHD 736
D
Sbjct: 772 QQD 774
>gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH domains
3 [Homo sapiens]
Length = 834
Score = 605 bits (1561), Expect = e-173
Identities = 371/819 (45%), Positives = 479/819 (58%), Gaps = 128/819 (15%)
Query: 5 LDFEECLKDSPRFRASIELVEAEVSELETRLEKLLKLGTGLLESGRHYLAASRAFVVGIC 64
++FEEC+KDSPRFRA+I+ VE +V E+E +L+KL+KL +G++E+G+ Y++ SR FV G+
Sbjct: 3 VEFEECVKDSPRFRATIDEVETDVVEIEAKLDKLVKLCSGMVEAGKAYVSTSRLFVSGVR 62
Query: 65 DLARLGPPEPMMAECLEKFTVSLNHKLDSHAELLDATQHTLQQQIQTLVKEGLRGFREAR 124
DL++ + +++ECL++F SL ++ H L D Q +++QQ+Q+ VKE +R F+E +
Sbjct: 63 DLSQQCQGDTVISECLQRFADSLQEVVNYHMILFDQAQRSVRQQLQSFVKEDVRKFKETK 122
Query: 125 RDFWRGAESLEAALTHNAEVPRRRAQEAEEAGAALRTARAGYRGRALDYALQINVIEDKR 184
+ F + E LE +L NA+ PR R E EEA AL R +R ALDY LQINV++ K+
Sbjct: 123 KQFDKVREDLELSLVRNAQAPRHRPHEVEEATGALTLTRKCFRHLALDYVLQINVLQAKK 182
Query: 185 KFDIMEFVLRLVEAQATHFQQGHEELSRLSQYRKELGAQLHQLVLNSAREKRDMEQRHVL 244
KF+I++ +L + AQ++ FQQG+ L +L Y K+L A+L QLV++SA EKR+ME++H
Sbjct: 183 KFEILDSMLSFMHAQSSFFQQGYSLLHQLDPYMKKLAAELDQLVIDSAVEKREMERKHAA 242
Query: 245 LKQKELGGEEPEPSLR-----EGPGGLVMEGHLFKRASNAFKTWSRRWFTIQSNQLVYQK 299
++Q+ L + + + P G+VMEG+LFKRASNAFKTW+RRWF+IQ++QLVYQK
Sbjct: 243 IQQRTLLQDFSYDESKVEFDVDAPSGVVMEGYLFKRASNAFKTWNRRWFSIQNSQLVYQK 302
Query: 300 KYKDPVTVVVDDLRLCTVKLCPDSERRFCFEVVSTSKSCLLQADSERLLQLWVSAVQSSI 359
K KD +TVVVDDLRLC+VK C D ERRFCFEV+S +KSC+LQADSE+L Q WV AVQ+SI
Sbjct: 303 KLKDALTVVVDDLRLCSVKPCEDIERRFCFEVLSPTKSCMLQADSEKLRQAWVQAVQASI 362
Query: 360 ASAFSQA-------RLDDSPRGPGQGSGHLAIGSAATLGSGGMARGREPGGVGHVVAQ-V 411
ASA+ ++ RLD + S +T RE G G V Q V
Sbjct: 363 ASAYRESPDSCYSERLDRT-------------ASPSTSSIDSATDTRERGVKGESVLQRV 409
Query: 412 QSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWEPELVK 471
QSV GN+QC DC +P P WASINLGV LCI+CSGIHRSLGVH SKVRSLTLDSWEPEL+K
Sbjct: 410 QSVAGNSQCGDCGQPDPRWASINLGVLLCIECSGIHRSLGVHCSKVRSLTLDSWEPELLK 469
Query: 472 LMCELGNVIINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLTKLPEIRGRRG 531
LMCELGN +NQIYEA+ E +KP S SRQ+KEAWI KYVEKKFL K P
Sbjct: 470 LMCELGNSAVNQIYEAQCEGAGSRKPTASSSRQDKEAWIKDKYVEKKFLRKAPMAPALEA 529
Query: 532 GRG-------RPRGQPPVP-PKPSIRPRP-----------GSLRSKPEPPS----EDLGS 568
R RP P P + +R P G+L K S ++L S
Sbjct: 530 PRRWRVQKCLRPHSSPRAPTARRKVRLEPVLPCVAALSSVGTLDRKFRRDSLFCPDELDS 589
Query: 569 LHPGALLFRASGHPPSLPT----------MADALA-------------HGADVNWVNGGQ 605
L A P SL + +D LA GA+ +G
Sbjct: 590 LFSYFDAGAAGAGPRSLSSDSGLGGSSDGSSDVLAFGSGSVVDSVTEEEGAESEESSGEA 649
Query: 606 DNATP-----------------LIQATAANSLLACEFLLQNGANVNQADSAGRG------ 642
D T +A A L A L +GA VN AD+ G
Sbjct: 650 DGDTEAEAWGLADVRELHPGLLAHRAARARDLPALAAALAHGAEVNWADAEDEGKTPLVQ 709
Query: 643 -----------------------------PLHHATILGHTGLACLFLKRGADLGARDSEG 673
PLHHAT+LG TG CLFLKRGAD A D E
Sbjct: 710 AVLGGSLIVCEFLLQNGADVNQRDSRGRAPLHHATLLGRTGQVCLFLKRGADQHALDQEQ 769
Query: 674 RDPLTIAMETANADIVTLLRLAK----MREAEAAQGQAG 708
RDPL IA++ ANADIVTLLRLA+ MREAEAA G G
Sbjct: 770 RDPLAIAVQAANADIVTLLRLARMAEEMREAEAAPGPPG 808
>gi|206597522 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
isoform b [Homo sapiens]
Length = 961
Score = 177 bits (448), Expect = 4e-44
Identities = 145/650 (22%), Positives = 264/650 (40%), Gaps = 91/650 (14%)
Query: 73 EPMMAECLEKFTVSLNHKLDSHAELLDATQHTLQQQIQTLVKEGLRGFR-EARRDFWRGA 131
+P + KF+V L+ + + + +L+K L+G + + ++ F +
Sbjct: 91 DPDLGSAFLKFSVFTKELTALFKNLIQNMNNIISFPLDSLLKGDLKGVKGDLKKPFDKAW 150
Query: 132 ESLEAALTHNAEVPRRRAQ---------EAEEAGAALRTARAGYRGRALDYALQINVIED 182
+ E +T + + A+ E + R ++ + +Y L++N I+
Sbjct: 151 KDYETKITKIEKEKKEHAKLHGMIRTEISGAEIAEEMEKERRFFQLQMCEYLLKVNEIKI 210
Query: 183 KRKFDIMEFVLRLVEAQATHFQQGHEELSRLSQYRKELGAQLHQLVLNSAREKRDMEQRH 242
K+ D+++ +++ AQ FQ G + + L + L LH + E+R + Q
Sbjct: 211 KKGVDLLQNLIKYFHAQCNFFQDGLKAVESLKPSIETLSTDLHTIKQAQDEERRQLIQLR 270
Query: 243 VLLKQKELGGEEPEPSLREGPG------------GLVMEGHLFKRASNAFKTWSRRWFTI 290
+LK ++ + +R+ G G L+K++ K W +R ++
Sbjct: 271 DILKSALQVEQKEDSQIRQSTAYSLHQPQGNKEHGTERNGSLYKKSDGIRKVWQKRKCSV 330
Query: 291 QSNQLV--YQKKYKDPVTVVVDDLRLCTVKLCPDSERRFCFEVVSTSKSCLLQADSERLL 348
++ L + + P + +L C VK P+ ++ CF+++S ++ QA+ E+
Sbjct: 331 KNGFLTISHGTANRPPAKL---NLLTCQVKTNPEEKK--CFDLISHDRTYHFQAEDEQEC 385
Query: 349 QLWVSAVQSSIASAFSQARLDDSPRGPGQGSGHLAIGSAATLGSGGMARGREPGGVGHVV 408
Q+W+S +Q+S A + A D G L ++
Sbjct: 386 QIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELT---------------------KEII 424
Query: 409 AQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWEPE 468
++VQ + GN CCDC P P W S NLG+ CI+CSGIHR LGVH+S+++SLTLD
Sbjct: 425 SEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDVLGTS 484
Query: 469 LVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLTKLPEIRG 528
+ L +GN N+I E + A KP P ++ +I AKY+E+++ K
Sbjct: 485 ELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARK------ 538
Query: 529 RRGGRGRPRGQPPVPPKPSIRPRPGSLRSKPEPPSEDLGSLHPGALLFRASGHPPSLPTM 588
+++ LH + L
Sbjct: 539 --------------------------------KHADNAAKLHSLCEAVKTRDIFGLLQAY 566
Query: 589 ADALAHGADVNWVNGGQDNATPL---IQATAANSLLACEFLLQNGANVNQADSAGRGPLH 645
AD + + NG + + T L +++ SL +FL+QN N+++ G LH
Sbjct: 567 ADGVDLTEKIPLANGHEPDETALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALH 626
Query: 646 HATILGHTGLACLFLKRGADLGARDSEGRDPLTIAMETANADIVTLLRLA 695
+ + + L L+ A + + G PL IA + LL A
Sbjct: 627 YCCLTDNAECLKLLLRGKASIEIANESGETPLDIAKRLKHEHCEELLTQA 676
>gi|4502249 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
isoform a [Homo sapiens]
Length = 1006
Score = 177 bits (448), Expect = 4e-44
Identities = 145/650 (22%), Positives = 264/650 (40%), Gaps = 91/650 (14%)
Query: 73 EPMMAECLEKFTVSLNHKLDSHAELLDATQHTLQQQIQTLVKEGLRGFR-EARRDFWRGA 131
+P + KF+V L+ + + + +L+K L+G + + ++ F +
Sbjct: 91 DPDLGSAFLKFSVFTKELTALFKNLIQNMNNIISFPLDSLLKGDLKGVKGDLKKPFDKAW 150
Query: 132 ESLEAALTHNAEVPRRRAQ---------EAEEAGAALRTARAGYRGRALDYALQINVIED 182
+ E +T + + A+ E + R ++ + +Y L++N I+
Sbjct: 151 KDYETKITKIEKEKKEHAKLHGMIRTEISGAEIAEEMEKERRFFQLQMCEYLLKVNEIKI 210
Query: 183 KRKFDIMEFVLRLVEAQATHFQQGHEELSRLSQYRKELGAQLHQLVLNSAREKRDMEQRH 242
K+ D+++ +++ AQ FQ G + + L + L LH + E+R + Q
Sbjct: 211 KKGVDLLQNLIKYFHAQCNFFQDGLKAVESLKPSIETLSTDLHTIKQAQDEERRQLIQLR 270
Query: 243 VLLKQKELGGEEPEPSLREGPG------------GLVMEGHLFKRASNAFKTWSRRWFTI 290
+LK ++ + +R+ G G L+K++ K W +R ++
Sbjct: 271 DILKSALQVEQKEDSQIRQSTAYSLHQPQGNKEHGTERNGSLYKKSDGIRKVWQKRKCSV 330
Query: 291 QSNQLV--YQKKYKDPVTVVVDDLRLCTVKLCPDSERRFCFEVVSTSKSCLLQADSERLL 348
++ L + + P + +L C VK P+ ++ CF+++S ++ QA+ E+
Sbjct: 331 KNGFLTISHGTANRPPAKL---NLLTCQVKTNPEEKK--CFDLISHDRTYHFQAEDEQEC 385
Query: 349 QLWVSAVQSSIASAFSQARLDDSPRGPGQGSGHLAIGSAATLGSGGMARGREPGGVGHVV 408
Q+W+S +Q+S A + A D G L ++
Sbjct: 386 QIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELT---------------------KEII 424
Query: 409 AQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWEPE 468
++VQ + GN CCDC P P W S NLG+ CI+CSGIHR LGVH+S+++SLTLD
Sbjct: 425 SEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDVLGTS 484
Query: 469 LVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLTKLPEIRG 528
+ L +GN N+I E + A KP P ++ +I AKY+E+++ K
Sbjct: 485 ELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARK------ 538
Query: 529 RRGGRGRPRGQPPVPPKPSIRPRPGSLRSKPEPPSEDLGSLHPGALLFRASGHPPSLPTM 588
+++ LH + L
Sbjct: 539 --------------------------------KHADNAAKLHSLCEAVKTRDIFGLLQAY 566
Query: 589 ADALAHGADVNWVNGGQDNATPL---IQATAANSLLACEFLLQNGANVNQADSAGRGPLH 645
AD + + NG + + T L +++ SL +FL+QN N+++ G LH
Sbjct: 567 ADGVDLTEKIPLANGHEPDETALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALH 626
Query: 646 HATILGHTGLACLFLKRGADLGARDSEGRDPLTIAMETANADIVTLLRLA 695
+ + + L L+ A + + G PL IA + LL A
Sbjct: 627 YCCLTDNAECLKLLLRGKASIEIANESGETPLDIAKRLKHEHCEELLTQA 676
>gi|19923540 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
isoform a [Homo sapiens]
Length = 903
Score = 174 bits (441), Expect = 3e-43
Identities = 161/637 (25%), Positives = 263/637 (41%), Gaps = 96/637 (15%)
Query: 113 VKEGLRGFREARRDFWRGAESLEAALTHNAEVPRRRAQEAEEAGAALRTARAGYRGRALD 172
+++G + ++ W+ E+ A L + R E ++ R ++ +
Sbjct: 136 LRDGRQDSKKQLEKAWKDYEAKMAKLEKERDRARVTGGIPGEVAQDMQRERRIFQLHMCE 195
Query: 173 YALQINVIEDKRKFDIMEFVLRLVEAQATHFQQGHEELSRLSQYRKELGAQLHQL----- 227
Y L+ + K+ D ++ +++ AQ FQ G + L + ++L A +H L
Sbjct: 196 YLLKAGESQMKQGPDFLQSLIKFFHAQHNFFQDGWKAAQSLFPFIEKLAASVHALHQAQE 255
Query: 228 --------VLNSAREKRDMEQRHVLLKQKELG-GEEPEPSLREGPGGLVMEGHLFKRASN 278
+ +S R +E R L +K G G G G L+K++
Sbjct: 256 DELQKLTQLRDSLRGTLQLESREEHLSRKNSGCGYSIHQHQGNKQFGTEKVGFLYKKSDG 315
Query: 279 AFKTWSRRWFTIQSNQLVYQKKYKDPVTVVVDDLRLCTVKLCPDSERRFCFEVVSTSKSC 338
+ W +R ++ L + V L L T ++ P+ E + CF++V+ +++
Sbjct: 316 IRRVWQKRKCGVKYGCLTISHSTINRPPV---KLTLLTCQVRPNPEEKKCFDLVTHNRTY 372
Query: 339 LLQADSERLLQLWVSAVQSSIASAFSQARLDDSPRGPGQGSGHLAIGSAATLGSGGMARG 398
QA+ E + WVS +Q+S A S A L + GPG GSA G
Sbjct: 373 HFQAEDEHECEAWVSVLQNSKDEALSSAFLGEPSAGPGSW------GSAGHDG------- 419
Query: 399 REPGGVGHV-VAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKV 457
EP + + +A+V+S GN+QCCDC P W S NLGV CIQCSG+HR LGV FS++
Sbjct: 420 -EPHDLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRM 478
Query: 458 RSLTLDSWEPELVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEK 517
+SLTLD P + L +GN N++ EA++ + KP + +I AKYVE
Sbjct: 479 QSLTLDLLGPSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYVEH 538
Query: 518 KFLTKLPEIRGRRGGRGRPRGQPPVPPKPSIRPRPGSLRSKPEPPSEDLGSLHPGALLFR 577
+F + R PEP L+
Sbjct: 539 RF----------------------------------ARRCTPEPQR-----------LWT 553
Query: 578 ASGHPPSLPTMADALAHGADVNWVNGGQDNATP-------LIQATAANSLLACEFLLQNG 630
A + L ++ +A A+G D G D P ++ SL +F++QNG
Sbjct: 554 AICN-RDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNG 612
Query: 631 ANVNQADSAGRGPLHHATILGHTGLACLFLKRGADLGARDSEGRDPLTIAMETANADIVT 690
+++ + G LH+A + L LK A +G + G L IA + + +
Sbjct: 613 GHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEE 672
Query: 691 LLRLAKMREAEAAQGQAGDETYLDIFRDFSLMASDDP 727
LL Q QAG + + D+S + S +P
Sbjct: 673 LLE----------QAQAGTFAF-PLHVDYSWVISTEP 698
>gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
isoform b [Homo sapiens]
Length = 894
Score = 171 bits (432), Expect = 3e-42
Identities = 167/645 (25%), Positives = 265/645 (41%), Gaps = 109/645 (16%)
Query: 109 IQTLVKEGLRGFREARRDFWRGAESLEAALTHNAEVPRRRAQEAE----EAGAALRTARA 164
+ +L+K LR R+A SL E R RA+ E ++ R
Sbjct: 128 LDSLMKGQLRDGRQA---------SLSLGSRAKLEKERDRARVTGGIPGEVAQDMQRERR 178
Query: 165 GYRGRALDYALQINVIEDKRKFDIMEFVLRLVEAQATHFQQGHEELSRLSQYRKELGAQL 224
++ +Y L+ + K+ D ++ +++ AQ FQ G + L + ++L A +
Sbjct: 179 IFQLHMCEYLLKAGESQMKQGPDFLQSLIKFFHAQHNFFQDGWKAAQSLFPFIEKLAASV 238
Query: 225 HQL-------------VLNSAREKRDMEQRHVLLKQKELG-GEEPEPSLREGPGGLVMEG 270
H L + +S R +E R L +K G G G G
Sbjct: 239 HALHQAQEDELQKLTQLRDSLRGTLQLESREEHLSRKNSGCGYSIHQHQGNKQFGTEKVG 298
Query: 271 HLFKRASNAFKTWSRRWFTIQSNQLVYQKKYKDPVTVVVDDLRLCTVKLCPDSERRFCFE 330
L+K++ + W +R ++ L + V L L T ++ P+ E + CF+
Sbjct: 299 FLYKKSDGIRRVWQKRKCGVKYGCLTISHSTINRPPV---KLTLLTCQVRPNPEEKKCFD 355
Query: 331 VVSTSKSCLLQADSERLLQLWVSAVQSSIASAFSQARLDDSPRGPGQGSGHLAIGSAATL 390
+V+ +++ QA+ E + WVS +Q+S A S A L + GPG GSA
Sbjct: 356 LVTHNRTYHFQAEDEHECEAWVSVLQNSKDEALSSAFLGEPSAGPGSW------GSAGHD 409
Query: 391 GSGGMARGREPGGVGHV-VAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRS 449
G EP + + +A+V+S GN+QCCDC P W S NLGV CIQCSG+HR
Sbjct: 410 G--------EPHDLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRE 461
Query: 450 LGVHFSKVRSLTLDSWEPELVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQEKEAW 509
LGV FS+++SLTLD P + L +GN N++ EA++ + KP + +
Sbjct: 462 LGVRFSRMQSLTLDLLGPSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDY 521
Query: 510 IHAKYVEKKFLTKLPEIRGRRGGRGRPRGQPPVPPKPSIRPRPGSLRSKPEPPSEDLGSL 569
I AKYVE +F + R PEP
Sbjct: 522 IMAKYVEHRF----------------------------------ARRCTPEPQR------ 541
Query: 570 HPGALLFRASGHPPSLPTMADALAHGADVNWVNGGQDNATP-------LIQATAANSLLA 622
L+ A + L ++ +A A+G D G D P ++ SL
Sbjct: 542 -----LWTAICN-RDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPL 595
Query: 623 CEFLLQNGANVNQADSAGRGPLHHATILGHTGLACLFLKRGADLGARDSEGRDPLTIAME 682
+F++QNG +++ + G LH+A + L LK A +G + G L IA +
Sbjct: 596 VDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARK 655
Query: 683 TANADIVTLLRLAKMREAEAAQGQAGDETYLDIFRDFSLMASDDP 727
+ + LL Q QAG + + D+S + S +P
Sbjct: 656 KHHKECEELLE----------QAQAGTFAF-PLHVDYSWVISTEP 689
>gi|46094081 development and differentiation enhancing factor 1
[Homo sapiens]
Length = 1129
Score = 165 bits (418), Expect = 1e-40
Identities = 152/704 (21%), Positives = 284/704 (40%), Gaps = 89/704 (12%)
Query: 18 RASIELVEAEVSELETRLEKLLKLGTGLLESGRHYLAASRAFVVGICDLAR--LGPPEPM 75
R ++ L+E + + T L+K+ K + SG+ ++ + + L P
Sbjct: 54 RNTVTLLEEALDQDRTALQKVKKSVKAIYNSGQDHVQNEENYAQVLDKFGSNFLSRDNPD 113
Query: 76 MAECLEKFTVSLNHKLDSHAELLDATQHTLQQQIQTLVKEGLRGFR-EARRDFWRGAESL 134
+ KF+ LL H + + +L+K L+G + + ++ F + +
Sbjct: 114 LGTAFVKFSTLTKELSTLLKNLLQGLSHNVIFTLDSLLKGDLKGVKGDLKKPFDKAWKDY 173
Query: 135 EAALTHNAEVPRRRAQE---------AEEAGAALRTARAGYRGRALDYALQINVIEDKRK 185
E T + R A++ E + R ++ + +Y +++N I+ K+
Sbjct: 174 ETKFTKIEKEKREHAKQHGMIRTEITGAEIAEEMEKERRLFQLQMCEYLIKVNEIKTKKG 233
Query: 186 FDIMEFVLRLVEAQATHFQQGHEELSRLSQYRKELGAQLHQLVLNSAREKRDMEQRHVLL 245
D+++ +++ AQ FQ G + +L QY ++L A L+ + EK+ + L+
Sbjct: 234 VDLLQNLIKYYHAQCNFFQDGLKTADKLKQYIEKLAADLYNIKQTQDEEKKQLTALRDLI 293
Query: 246 KQKELGGEEPEPSLREG-----------PGGLVMEGHLFKRASNAFKTWSRRWFTIQSNQ 294
K ++ + R+G G +G+L K++ K W RR ++++
Sbjct: 294 KSSLQLDQKEDSQSRQGGYSMHQLQGNKEYGSEKKGYLLKKSDGIRKVWQRRKCSVKNGI 353
Query: 295 LV--YQKKYKDPVTVVVDDLRLCTVKLCPDSERRFCFEVVSTSKSCLLQADSERLLQLWV 352
L + + P L L T ++ P++E + F+++S +++ QA+ E+ W+
Sbjct: 354 LTISHATSNRQPAK-----LNLLTCQVKPNAEDKKSFDLISHNRTYHFQAEDEQDYVAWI 408
Query: 353 SAVQSSIASAFSQARLDDSPRGPGQGSGHLAIGSAATLGSGGMARGREPGGVGHVVAQVQ 412
S + +S A + A + Q +G ++ ++ VQ
Sbjct: 409 SVLTNSKEEALTMAFRGE------QSAGENSLEDLTKA----------------IIEDVQ 446
Query: 413 SVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWEPELVKL 472
+ GN CCDC P W S NLG+ CI+CSGIHR +GVH S+++SL LD + L
Sbjct: 447 RLPGNDICCDCGSSEPTWLSTNLGILTCIECSGIHREMGVHISRIQSLELDKLGTSELLL 506
Query: 473 MCELGNVIINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLTKLPEIRGRRGG 532
+GN N I EA + + + KP PS ++ +I AKYV+ +F K
Sbjct: 507 AKNVGNNSFNDIMEANLPSPS-PKPTPSSDMTVRKEYITAKYVDHRFSRK---------- 555
Query: 533 RGRPRGQPPVPPKPSIRPRPGSLRSKPEPPSEDLGSLHPGALLFRASGHPPSLPTMADAL 592
+ + +E L ++ LL + + M L
Sbjct: 556 ---------------------TCSTSSAKLNELLEAIKSRDLLALIQVYAEGVELMEPLL 594
Query: 593 AHGADVNWVNGGQDNATPLIQATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILGH 652
G ++ G+ ++ SL +FL+QN N+++ + G LH+ ++
Sbjct: 595 EPGQEL-----GETALHLAVRTADQTSLHLVDFLVQNCGNLDKQTALGNTVLHYCSMYSK 649
Query: 653 TGLACLFLKRGADLGARDSEGRDPLTIAMETANADIVTLLRLAK 696
L L+ + + G L IA LL AK
Sbjct: 650 PECLKLLLRSKPTVDIVNQAGETALDIAKRLKATQCEDLLSQAK 693
Score = 30.8 bits (68), Expect = 4.7
Identities = 26/70 (37%), Positives = 32/70 (45%), Gaps = 12/70 (17%)
Query: 536 PRGQPP--VPPKPS-IRPRP--GSLRSKPE--PPSEDLGSLHPGALLFRASGHP-----P 583
P+ PP +PPKP+ + P+P G L KP PP LG L P L P P
Sbjct: 931 PQKPPPGDLPPKPTELAPKPQIGDLPPKPGELPPKPQLGDLPPKPQLSDLPPKPQMKDLP 990
Query: 584 SLPTMADALA 593
P + D LA
Sbjct: 991 PKPQLGDLLA 1000
>gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens]
Length = 911
Score = 149 bits (376), Expect = 9e-36
Identities = 110/361 (30%), Positives = 161/361 (44%), Gaps = 74/361 (20%)
Query: 322 DSERRFCFEVVS-TSKSCLLQADSERLLQLWVSAVQSSIASAFSQARLDDSPRGPGQGSG 380
++E F F VVS T ++ +A + +LWV +VQ+ I ++ R G +
Sbjct: 602 EAEESFEFVVVSLTGQTWHFEASTAEERELWVQSVQAQILASLQGCRSAKDKTRLGNQNA 661
Query: 381 HLAIGSAATLGSGGMARGREPGGVGHVVAQVQSVDGNAQCCDCREPAPEWASINLGVTLC 440
LA+ + V++V GN+ C DC P P+WAS+NLG +C
Sbjct: 662 ALAVQA------------------------VRTVRGNSFCIDCDAPNPDWASLNLGALMC 697
Query: 441 IQCSGIHRSLGVHFSKVRSLTLDSWEPELVKLMCELGNVIINQIYEARVEAMAVKKPGPS 500
I+CSGIHR LG H S+VRSL LD W PEL+ +M +GN + N ++E + + KPGP
Sbjct: 698 IECSGIHRHLGAHLSRVRSLDLDDWPPELLAVMTAMGNALANSVWEGALGGYS--KPGPD 755
Query: 501 CSRQEKEAWIHAKYVEKKFLTKLPEIRGRRGGRGRPRGQPPVPPKPSIRPRPGSLRSKPE 560
R+EKE WI AKY +K FL LP P GQ LR+ E
Sbjct: 756 ACREEKERWIRAKYEQKLFLAPLP-------SSDVPLGQQ-------------LLRAVVE 795
Query: 561 PPSEDLGSLHPGALLFRASGHPPSLPTMADALAHGA--DVNWVNGGQDNATPLIQATAAN 618
L + LAHG+ +VN G D T L ++A
Sbjct: 796 ----------------------DDLRLLVMLLAHGSKEEVNETYGDGDGRTALHLSSAMA 833
Query: 619 SLLACEFLLQNGANVNQADSAGRGPLHHATILGHTGLACLFLKRGA---DLGARDSEGRD 675
+++ + L+ G +V D+ G PL +A G A + ++ G G + R+
Sbjct: 834 NVVFTQLLIWYGVDVRSRDARGLTPLAYARRAGSQECADILIQHGCPGEGCGLAPTPNRE 893
Query: 676 P 676
P
Sbjct: 894 P 894
Score = 34.7 bits (78), Expect = 0.33
Identities = 22/86 (25%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Query: 611 LIQATAANSLLACEFLLQNGA----NVNQADSAGRGPLHHATILGHTGLACLFLKRGADL 666
L++A + L LL +G+ N D GR LH ++ + + L + G D+
Sbjct: 789 LLRAVVEDDLRLLVMLLAHGSKEEVNETYGDGDGRTALHLSSAMANVVFTQLLIWYGVDV 848
Query: 667 GARDSEGRDPLTIAMETANADIVTLL 692
+RD+ G PL A + + +L
Sbjct: 849 RSRDARGLTPLAYARRAGSQECADIL 874
>gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 4 [Homo sapiens]
Length = 663
Score = 131 bits (329), Expect = 3e-30
Identities = 122/428 (28%), Positives = 172/428 (40%), Gaps = 94/428 (21%)
Query: 267 VMEGHLFKRASNAFKTWSRRWFTIQSNQ-LVYQKKYKDPVTVVVD---DLRLCTVKL--- 319
+ +G L KR+ KTW +++ T+ SN L Y D + + DL+ T+K+
Sbjct: 261 IKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLQTSTIKVPGK 320
Query: 320 CPDSERRFCFEVVSTSKSCLLQADSERLLQLWVSAVQSSIASAFSQARLDDSPRGPGQGS 379
P C + STSKS L D + L S S S+ + +L+ P
Sbjct: 321 WPSLATSACTPI-STSKSNGLSKDMDT--GLGDSICFSPSISSTTSPKLNPPPSPHANKK 377
Query: 380 GHLAIGSA-----------------------------------ATLGSGGMARGREP--- 401
HL S A+L S ++ +
Sbjct: 378 KHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTS 437
Query: 402 GGVGHVVAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLT 461
+ +Q++ GNA C DC P+WAS+NLGV +CI+CSGIHRSLG S+VRSL
Sbjct: 438 QSKAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLE 497
Query: 462 LDSWEPELVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLT 521
LD W EL K+M +GN + N I+E + KP +R+EKE WI +KY EK FL
Sbjct: 498 LDDWPVELRKVMSSIGNDLANSIWEGSSQGQT--KPSEKSTREEKERWIRSKYEEKLFLA 555
Query: 522 KLPEIRGRRGGRGRPRGQPPVPPKPSIRPRPGSLRSKPEPPSEDLGSLHPGALLFRASGH 581
LP L G L RA+
Sbjct: 556 PLP-----------------------------------------CTELSLGQQLLRATA- 573
Query: 582 PPSLPTMADALAHGA--DVNWVNGGQDNATPLIQATAANSLLACEFLLQNGANVNQADSA 639
L T LAHG+ +VN G D T L A +++ + L+ G +V D+
Sbjct: 574 DEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAH 633
Query: 640 GRGPLHHA 647
G L +A
Sbjct: 634 GNTALTYA 641
Score = 41.2 bits (95), Expect = 0.004
Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 611 LIQATAANSLLACEFLLQNGANVNQADSAGRGP----LHHATILGHTGLACLFLKRGADL 666
L++ATA L LL +G+ ++ G G LH A G+ LA L + G D+
Sbjct: 568 LLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDV 627
Query: 667 GARDSEGRDPLTIAMETANADIVTLL 692
ARD+ G LT A + ++ + + +L
Sbjct: 628 MARDAHGNTALTYARQASSQECINVL 653
>gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activating
protein 11 [Homo sapiens]
Length = 550
Score = 130 bits (326), Expect = 6e-30
Identities = 100/322 (31%), Positives = 137/322 (42%), Gaps = 71/322 (22%)
Query: 329 FEVVS-TSKSCLLQADSERLLQLWVSAVQSSIASAFSQARLDDSPRGPGQGSGHLAIGSA 387
F +VS T ++C +A + WV A+QS I ++ S S
Sbjct: 275 FMIVSVTGQTCHFKATTYEERDAWVQAIQSQILASLQSCESSKSK-------------SQ 321
Query: 388 ATLGSGGMARGREPGGVGHVVAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIH 447
T S MA + +Q++ GN+ C DC P+WAS+NLGV +CI+CSGIH
Sbjct: 322 LTSQSEAMA-----------LQSIQNMRGNSHCVDCETQNPKWASLNLGVLMCIECSGIH 370
Query: 448 RSLGVHFSKVRSLTLDSWEPELVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQEKE 507
RSLG S+VRSL LD W EL K+M +GN + N I+E + KP +R+EKE
Sbjct: 371 RSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQT--KPSIESTREEKE 428
Query: 508 AWIHAKYVEKKFLTKLPEIRGRRGGRGRPRGQPPVPPKPSIRPRPGSLRSKPEPPSEDLG 567
WI +KY K FL LP
Sbjct: 429 RWIRSKYEHKLFLAPLP-----------------------------------------CT 447
Query: 568 SLHPGALLFRASGHPPSLPTMADALAHGA--DVNWVNGGQDNATPLIQATAANSLLACEF 625
L G L RA+ L T LAHG+ +VN G D T L A +++ +
Sbjct: 448 ELSLGQHLLRATA-DEDLRTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQL 506
Query: 626 LLQNGANVNQADSAGRGPLHHA 647
L+ G +V D+ G L +A
Sbjct: 507 LIWYGVDVMARDAHGNTALTYA 528
Score = 41.2 bits (95), Expect = 0.004
Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 611 LIQATAANSLLACEFLLQNGANVNQADSAGRGP----LHHATILGHTGLACLFLKRGADL 666
L++ATA L LL +G+ ++ G G LH A G+ LA L + G D+
Sbjct: 455 LLRATADEDLRTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDV 514
Query: 667 GARDSEGRDPLTIAMETANADIVTLL 692
ARD+ G LT A + ++ + + +L
Sbjct: 515 MARDAHGNTALTYARQASSQECINVL 540
>gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens]
Length = 686
Score = 129 bits (325), Expect = 7e-30
Identities = 99/319 (31%), Positives = 135/319 (42%), Gaps = 70/319 (21%)
Query: 331 VVSTSKSCLLQADSERLLQLWVSAVQSSIASAFSQARLDDSPRGPGQGSGHLAIGSAATL 390
V +T ++ +A + WV A+QS I ++ S S T
Sbjct: 414 VSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCESSKSK-------------SQLTS 460
Query: 391 GSGGMARGREPGGVGHVVAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSL 450
S MA + +Q++ GNA C DC P+WAS+NLGV +CI+CSGIHRSL
Sbjct: 461 QSEAMA-----------LQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSL 509
Query: 451 GVHFSKVRSLTLDSWEPELVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQEKEAWI 510
G H S+VRSL LD W EL K+M + N + N I+E + KP +R+EKE WI
Sbjct: 510 GPHLSRVRSLELDDWPVELRKVMSSIVNDLANSIWEGSSQGQT--KPSEKSTREEKERWI 567
Query: 511 HAKYVEKKFLTKLPEIRGRRGGRGRPRGQPPVPPKPSIRPRPGSLRSKPEPPSEDLGSLH 570
+KY EK FL LP L
Sbjct: 568 RSKYEEKLFLAPLP-----------------------------------------CTELS 586
Query: 571 PGALLFRASGHPPSLPTMADALAHGA--DVNWVNGGQDNATPLIQATAANSLLACEFLLQ 628
G L RA+ L T LAHG+ +VN G D T L A +++ + L+
Sbjct: 587 LGQQLLRATA-DEDLQTAILLLAHGSCEEVNETCGEGDGCTALHLACRKGNVVLAQLLIW 645
Query: 629 NGANVNQADSAGRGPLHHA 647
G +V D+ G L +A
Sbjct: 646 YGVDVMARDAHGNTALTYA 664
Score = 40.4 bits (93), Expect = 0.006
Identities = 29/86 (33%), Positives = 44/86 (51%), Gaps = 4/86 (4%)
Query: 611 LIQATAANSLLACEFLLQNGA--NVNQADSAGRG--PLHHATILGHTGLACLFLKRGADL 666
L++ATA L LL +G+ VN+ G G LH A G+ LA L + G D+
Sbjct: 591 LLRATADEDLQTAILLLAHGSCEEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDV 650
Query: 667 GARDSEGRDPLTIAMETANADIVTLL 692
ARD+ G LT A + ++ + + +L
Sbjct: 651 MARDAHGNTALTYARQASSQECINVL 676
>gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens]
Length = 804
Score = 129 bits (325), Expect = 7e-30
Identities = 97/329 (29%), Positives = 140/329 (42%), Gaps = 71/329 (21%)
Query: 322 DSERRFCFEVVS-TSKSCLLQADSERLLQLWVSAVQSSIASAFSQARLDDSPRGPGQGSG 380
+ E F F +VS T ++ +A + WV A++S I ++ +
Sbjct: 496 EQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNK-------- 547
Query: 381 HLAIGSAATLGSGGMARGREPGGVGHVVAQVQSVDGNAQCCDCREPAPEWASINLGVTLC 440
S T S MA + ++++ GN+ C DC P WAS+NLG +C
Sbjct: 548 -----SRLTSQSEAMA-----------LQSIRNMRGNSHCVDCETQNPNWASLNLGALMC 591
Query: 441 IQCSGIHRSLGVHFSKVRSLTLDSWEPELVKLMCELGNVIINQIYEARVEAMAVKKPGPS 500
I+CSGIHR+LG H S+VRSL LD W EL+K+M +GN + N ++E + KP
Sbjct: 592 IECSGIHRNLGTHLSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRT--KPSVD 649
Query: 501 CSRQEKEAWIHAKYVEKKFLTKLPEIRGRRGGRGRPRGQPPVPPKPSIRPRPGSLRSKPE 560
+R+EKE WI AKY +K FL LP
Sbjct: 650 STREEKERWIRAKYEQKLFLAPLP------------------------------------ 673
Query: 561 PPSEDLGSLHPGALLFRASGHPPSLPTMADALAHGA--DVNWVNGGQDNATPLIQATAAN 618
L G L RA+ L T LAHG+ +VN G D T L A
Sbjct: 674 -----CTELSLGQHLLRATA-DEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKG 727
Query: 619 SLLACEFLLQNGANVNQADSAGRGPLHHA 647
+++ + L+ G +V D+ G L +A
Sbjct: 728 NVVLAQLLIWYGVDVTARDAHGNTALAYA 756
Score = 39.7 bits (91), Expect = 0.010
Identities = 28/86 (32%), Positives = 44/86 (51%), Gaps = 4/86 (4%)
Query: 611 LIQATAANSLLACEFLLQNGAN--VNQA--DSAGRGPLHHATILGHTGLACLFLKRGADL 666
L++ATA L LL +G+ VN+ + GR LH A G+ LA L + G D+
Sbjct: 683 LLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDV 742
Query: 667 GARDSEGRDPLTIAMETANADIVTLL 692
ARD+ G L A + ++ + + +L
Sbjct: 743 TARDAHGNTALAYARQASSQECIDVL 768
>gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens]
Length = 857
Score = 129 bits (325), Expect = 7e-30
Identities = 97/329 (29%), Positives = 140/329 (42%), Gaps = 71/329 (21%)
Query: 322 DSERRFCFEVVS-TSKSCLLQADSERLLQLWVSAVQSSIASAFSQARLDDSPRGPGQGSG 380
+ E F F +VS T ++ +A + WV A++S I ++ +
Sbjct: 549 EQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNK-------- 600
Query: 381 HLAIGSAATLGSGGMARGREPGGVGHVVAQVQSVDGNAQCCDCREPAPEWASINLGVTLC 440
S T S MA + ++++ GN+ C DC P WAS+NLG +C
Sbjct: 601 -----SRLTSQSEAMA-----------LQSIRNMRGNSHCVDCETQNPNWASLNLGALMC 644
Query: 441 IQCSGIHRSLGVHFSKVRSLTLDSWEPELVKLMCELGNVIINQIYEARVEAMAVKKPGPS 500
I+CSGIHR+LG H S+VRSL LD W EL+K+M +GN + N ++E + KP
Sbjct: 645 IECSGIHRNLGTHLSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRT--KPSVD 702
Query: 501 CSRQEKEAWIHAKYVEKKFLTKLPEIRGRRGGRGRPRGQPPVPPKPSIRPRPGSLRSKPE 560
+R+EKE WI AKY +K FL LP
Sbjct: 703 STREEKERWIRAKYEQKLFLAPLP------------------------------------ 726
Query: 561 PPSEDLGSLHPGALLFRASGHPPSLPTMADALAHGA--DVNWVNGGQDNATPLIQATAAN 618
L G L RA+ L T LAHG+ +VN G D T L A
Sbjct: 727 -----CTELSLGQHLLRATA-DEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKG 780
Query: 619 SLLACEFLLQNGANVNQADSAGRGPLHHA 647
+++ + L+ G +V D+ G L +A
Sbjct: 781 NVVLAQLLIWYGVDVTARDAHGNTALAYA 809
Score = 39.7 bits (91), Expect = 0.010
Identities = 28/86 (32%), Positives = 44/86 (51%), Gaps = 4/86 (4%)
Query: 611 LIQATAANSLLACEFLLQNGAN--VNQA--DSAGRGPLHHATILGHTGLACLFLKRGADL 666
L++ATA L LL +G+ VN+ + GR LH A G+ LA L + G D+
Sbjct: 736 LLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDV 795
Query: 667 GARDSEGRDPLTIAMETANADIVTLL 692
ARD+ G L A + ++ + + +L
Sbjct: 796 TARDAHGNTALAYARQASSQECIDVL 821
>gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 7 [Homo sapiens]
Length = 663
Score = 129 bits (325), Expect = 7e-30
Identities = 99/319 (31%), Positives = 135/319 (42%), Gaps = 70/319 (21%)
Query: 331 VVSTSKSCLLQADSERLLQLWVSAVQSSIASAFSQARLDDSPRGPGQGSGHLAIGSAATL 390
V +T ++ +A + WV A+QS I ++ S S T
Sbjct: 391 VSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCESSKSK-------------SQLTS 437
Query: 391 GSGGMARGREPGGVGHVVAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSL 450
S MA + +Q++ GNA C DC P+WAS+NLGV +CI+CSGIHRSL
Sbjct: 438 QSEAMA-----------LQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSL 486
Query: 451 GVHFSKVRSLTLDSWEPELVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQEKEAWI 510
G S+VRSL LD W EL K+M +GN + N I+E + KP +R+EKE WI
Sbjct: 487 GTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRT--KPTEKSTREEKERWI 544
Query: 511 HAKYVEKKFLTKLPEIRGRRGGRGRPRGQPPVPPKPSIRPRPGSLRSKPEPPSEDLGSLH 570
+KY EK FL LP L
Sbjct: 545 RSKYEEKLFLAPLP-----------------------------------------CTELS 563
Query: 571 PGALLFRASGHPPSLPTMADALAHGA--DVNWVNGGQDNATPLIQATAANSLLACEFLLQ 628
G L RA+ L T LAHG+ +VN G D T L A +++ + L+
Sbjct: 564 LGQQLLRATA-DEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIW 622
Query: 629 NGANVNQADSAGRGPLHHA 647
G +V D+ G L +A
Sbjct: 623 YGVDVMARDAHGNTALTYA 641
Score = 41.2 bits (95), Expect = 0.004
Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 611 LIQATAANSLLACEFLLQNGANVNQADSAGRGP----LHHATILGHTGLACLFLKRGADL 666
L++ATA L LL +G+ ++ G G LH A G+ LA L + G D+
Sbjct: 568 LLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDV 627
Query: 667 GARDSEGRDPLTIAMETANADIVTLL 692
ARD+ G LT A + ++ + + +L
Sbjct: 628 MARDAHGNTALTYARQASSQECINVL 653
>gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
and PH domain 9 [Homo sapiens]
Length = 684
Score = 126 bits (317), Expect = 6e-29
Identities = 73/194 (37%), Positives = 99/194 (51%), Gaps = 26/194 (13%)
Query: 331 VVSTSKSCLLQADSERLLQLWVSAVQSSIASAFSQARLDDSPRGPGQGSGHLAIGSAATL 390
V +T ++ +A + WV A+QS I ++ + S S T
Sbjct: 414 VSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCKSSKSK-------------SQLTS 460
Query: 391 GSGGMARGREPGGVGHVVAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSL 450
S MA + +Q++ GNA C DC P+WAS+NLGV +CI+CSGIHRS
Sbjct: 461 QSEAMA-----------LQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSF 509
Query: 451 GVHFSKVRSLTLDSWEPELVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQEKEAWI 510
G S+VRSL LD W EL K+M +GN + N I+E + KP +R+EKE WI
Sbjct: 510 GTRLSRVRSLELDDWPVELRKVMSSIGNELANSIWEGSSQGQT--KPSIKSTREEKEWWI 567
Query: 511 HAKYVEKKFLTKLP 524
+KY EK FL LP
Sbjct: 568 RSKYEEKLFLAPLP 581
Score = 33.5 bits (75), Expect = 0.73
Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 6/86 (6%)
Query: 611 LIQATAANSLLACEFLLQNGANVNQADSAGRGP----LHHATILGHTGLACLFLKRGADL 666
L++AT L LL +G+ ++ G G LH A G+ L L G D+
Sbjct: 591 LLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLLX--GVDV 648
Query: 667 GARDSEGRDPLTIAMETANADIVTLL 692
ARD+ G LT A + ++ + + +L
Sbjct: 649 MARDAHGNTALTYARQASSQECINVL 674
>gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
and PH domain 10 [Homo sapiens]
Length = 684
Score = 126 bits (317), Expect = 6e-29
Identities = 73/194 (37%), Positives = 99/194 (51%), Gaps = 26/194 (13%)
Query: 331 VVSTSKSCLLQADSERLLQLWVSAVQSSIASAFSQARLDDSPRGPGQGSGHLAIGSAATL 390
V +T ++ +A + WV A+QS I ++ + S S T
Sbjct: 414 VSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCKSSKSK-------------SQLTS 460
Query: 391 GSGGMARGREPGGVGHVVAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSL 450
S MA + +Q++ GNA C DC P+WAS+NLGV +CI+CSGIHRS
Sbjct: 461 QSEAMA-----------LQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSF 509
Query: 451 GVHFSKVRSLTLDSWEPELVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQEKEAWI 510
G S+VRSL LD W EL K+M +GN + N I+E + KP +R+EKE WI
Sbjct: 510 GTRLSRVRSLELDDWPVELRKVMSSIGNELANSIWEGSSQGQT--KPSIKSTREEKEWWI 567
Query: 511 HAKYVEKKFLTKLP 524
+KY EK FL LP
Sbjct: 568 RSKYEEKLFLAPLP 581
Score = 33.5 bits (75), Expect = 0.73
Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 6/86 (6%)
Query: 611 LIQATAANSLLACEFLLQNGANVNQADSAGRGP----LHHATILGHTGLACLFLKRGADL 666
L++AT L LL +G+ ++ G G LH A G+ L L G D+
Sbjct: 591 LLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLLX--GVDV 648
Query: 667 GARDSEGRDPLTIAMETANADIVTLL 692
ARD+ G LT A + ++ + + +L
Sbjct: 649 MARDAHGNTALTYARQASSQECINVL 674
>gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 8 [Homo sapiens]
Length = 663
Score = 126 bits (317), Expect = 6e-29
Identities = 73/194 (37%), Positives = 98/194 (50%), Gaps = 26/194 (13%)
Query: 331 VVSTSKSCLLQADSERLLQLWVSAVQSSIASAFSQARLDDSPRGPGQGSGHLAIGSAATL 390
V +T ++ +A + WV A+QS I ++ S S T
Sbjct: 391 VSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCESSKSK-------------SQLTS 437
Query: 391 GSGGMARGREPGGVGHVVAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSL 450
S MA + +Q++ GNA C DC P+WAS+NLGV +CI+CSGIH SL
Sbjct: 438 QSEAMA-----------LQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHHSL 486
Query: 451 GVHFSKVRSLTLDSWEPELVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQEKEAWI 510
G S+VRSL LD W EL K+M +GN + N I+E + KP +R+EKE WI
Sbjct: 487 GTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQT--KPSEKSTREEKERWI 544
Query: 511 HAKYVEKKFLTKLP 524
+KY EK FL LP
Sbjct: 545 RSKYEEKLFLAPLP 558
Score = 40.0 bits (92), Expect = 0.008
Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 611 LIQATAANSLLACEFLLQNGANVNQADSAGRGP----LHHATILGHTGLACLFLKRGADL 666
L+ ATA L LL +G+ ++ G G LH A G+ LA L + G D+
Sbjct: 568 LLWATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDV 627
Query: 667 GARDSEGRDPLTIAMETANADIVTLL 692
ARD+ G LT A + ++ + + +L
Sbjct: 628 MARDAHGNTALTYARQASSQECINVL 653
>gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 5 [Homo sapiens]
Length = 686
Score = 126 bits (316), Expect = 8e-29
Identities = 121/428 (28%), Positives = 171/428 (39%), Gaps = 94/428 (21%)
Query: 267 VMEGHLFKRASNAFKTWSRRWFTIQSNQ-LVYQKKYKDPVTVVVD---DLRLCTVKL--- 319
+ +G L KR+ KTW +++ T+ SN L Y D + + DLR T+K+
Sbjct: 284 IKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGK 343
Query: 320 CPDSERRFCFEVVSTSKSCLLQADSERLLQLWVSAVQSSIASAFSQARLDDSPRGPGQGS 379
P C + S+SKS L D + L S S S+ + +L+ P
Sbjct: 344 WPSLATSACAPI-SSSKSNGLSKDMDT--GLGDSICFSPSISSTTSPKLNPPPSPHANKK 400
Query: 380 GHLAIGSA-----------------------------------ATLGSGGMARGREP--- 401
HL S A+L S ++ +
Sbjct: 401 KHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTS 460
Query: 402 GGVGHVVAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLT 461
+ +Q++ GNA C D P+WAS+NLGV +CI+CSGIHRSLG S+VRSL
Sbjct: 461 QSEAMALQSIQNMRGNAHCVDYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLE 520
Query: 462 LDSWEPELVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLT 521
LD W EL K+M +GN + N I+E + KP +R+EKE WI +KY EK FL
Sbjct: 521 LDDWPVELRKVMSSIGNDLANSIWEGSSQGQT--KPSVKSTREEKERWIRSKYEEKLFLA 578
Query: 522 KLPEIRGRRGGRGRPRGQPPVPPKPSIRPRPGSLRSKPEPPSEDLGSLHPGALLFRASGH 581
LP L G L RA+
Sbjct: 579 PLP-----------------------------------------CTELSLGQHLLRATA- 596
Query: 582 PPSLPTMADALAHGA--DVNWVNGGQDNATPLIQATAANSLLACEFLLQNGANVNQADSA 639
L T LAHG+ +VN G D T L A +++ + L+ G +V D+
Sbjct: 597 DEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAH 656
Query: 640 GRGPLHHA 647
G L +A
Sbjct: 657 GNTALTYA 664
Score = 41.2 bits (95), Expect = 0.004
Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 611 LIQATAANSLLACEFLLQNGANVNQADSAGRGP----LHHATILGHTGLACLFLKRGADL 666
L++ATA L LL +G+ ++ G G LH A G+ LA L + G D+
Sbjct: 591 LLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDV 650
Query: 667 GARDSEGRDPLTIAMETANADIVTLL 692
ARD+ G LT A + ++ + + +L
Sbjct: 651 MARDAHGNTALTYARQASSQECINVL 676
>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
Length = 1192
Score = 116 bits (291), Expect = 7e-26
Identities = 87/300 (29%), Positives = 131/300 (43%), Gaps = 48/300 (16%)
Query: 408 VAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWEP 467
+ +++ GN+ C DC P P WAS+NLG +CI+CSGIHR+LG H S+VRSL LD W
Sbjct: 934 IQAIRNAKGNSICVDCGAPNPTWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDDWPR 993
Query: 468 ELVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLTKLPEIR 527
EL ++ +GN N+++E+ A KP SR+E+E+WI AKY + FL L
Sbjct: 994 ELTLVLTAIGNDTANRVWESDTRGRA--KPSRDSSREERESWIRAKYEQLLFLAPL---- 1047
Query: 528 GRRGGRGRPRGQPPVPPKPSIRPRPGSLRSKPEPPSEDLGSLHPGALLFRASGHPPSLPT 587
S P + ++D+ ++ LL + H P +
Sbjct: 1048 -------------------STSEEPLGRQLWAAVQAQDVATV---LLLLAHARHGPLDTS 1085
Query: 588 MADALAHGADVNWVNGGQDNATPLIQATAANSLLACEFLLQNGANVNQADSAGRGPLHHA 647
+ D +PL A ++ + LL GA+V D+ GR L +A
Sbjct: 1086 VEDPQLR--------------SPLHLAAELAHVVITQLLLWYGADVAARDAQGRTALFYA 1131
Query: 648 TILGHTGLACLFLKRGADLGARDSEGRDPLTIAMETANADIVTLLRLAKMREAEAAQGQA 707
G A + L+ G EG T A +T + R + A+ G+A
Sbjct: 1132 RQAGSQLCADILLQHGC-----PGEGGSAAT-TPSAATTPSITATPSPRRRSSAASVGRA 1185
>gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens]
Length = 836
Score = 116 bits (291), Expect = 7e-26
Identities = 87/300 (29%), Positives = 131/300 (43%), Gaps = 48/300 (16%)
Query: 408 VAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWEP 467
+ +++ GN+ C DC P P WAS+NLG +CI+CSGIHR+LG H S+VRSL LD W
Sbjct: 578 IQAIRNAKGNSICVDCGAPNPTWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDDWPR 637
Query: 468 ELVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLTKLPEIR 527
EL ++ +GN N+++E+ A KP SR+E+E+WI AKY + FL L
Sbjct: 638 ELTLVLTAIGNDTANRVWESDTRGRA--KPSRDSSREERESWIRAKYEQLLFLAPL---- 691
Query: 528 GRRGGRGRPRGQPPVPPKPSIRPRPGSLRSKPEPPSEDLGSLHPGALLFRASGHPPSLPT 587
S P + ++D+ ++ LL + H P +
Sbjct: 692 -------------------STSEEPLGRQLWAAVQAQDVATV---LLLLAHARHGPLDTS 729
Query: 588 MADALAHGADVNWVNGGQDNATPLIQATAANSLLACEFLLQNGANVNQADSAGRGPLHHA 647
+ D +PL A ++ + LL GA+V D+ GR L +A
Sbjct: 730 VEDPQLR--------------SPLHLAAELAHVVITQLLLWYGADVAARDAQGRTALFYA 775
Query: 648 TILGHTGLACLFLKRGADLGARDSEGRDPLTIAMETANADIVTLLRLAKMREAEAAQGQA 707
G A + L+ G EG T A +T + R + A+ G+A
Sbjct: 776 RQAGSQLCADILLQHGC-----PGEGGSAAT-TPSAATTPSITATPSPRRRSSAASVGRA 829
>gi|23943872 small ArfGAP2 [Homo sapiens]
Length = 429
Score = 100 bits (249), Expect = 5e-21
Identities = 55/142 (38%), Positives = 82/142 (57%), Gaps = 8/142 (5%)
Query: 407 VVAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWE 466
V+A + + N C DC+ P WAS N+GV +CI+C+GIHR+LGVH S+V+S+ LD W
Sbjct: 15 VLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWT 74
Query: 467 PELVKLMCELGNVIINQIYEARV-EAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLTKLPE 525
E ++ M E+GN N++YEA + E + P+ E +I KY +KK++ + +
Sbjct: 75 QEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAV-----EGFIRDKYEKKKYMDRSLD 129
Query: 526 IRGRRGGRGR--PRGQPPVPPK 545
I R + RG PVP K
Sbjct: 130 INAFRKEKDDKWKRGSEPVPEK 151
>gi|6806913 centaurin, alpha 1 [Homo sapiens]
Length = 374
Score = 95.9 bits (237), Expect = 1e-19
Identities = 72/206 (34%), Positives = 103/206 (50%), Gaps = 29/206 (14%)
Query: 416 GNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWEPELVKLMCE 475
GNA+C DC P P+WAS LGV +C+ CSGIHR++ SKV+S+ LD+WE V+ M
Sbjct: 17 GNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVRLDAWEEAQVEFMAS 75
Query: 476 LGNVIINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFL---TKLPEIRGRRGG 532
GN +E++V + +P PS + +E WI AKY ++F+ + P G R G
Sbjct: 76 HGNDAARARFESKVPSF-YYRPTPSDCQLLREQWIRAKYERQEFIYPEKQEPYSAGYREG 134
Query: 533 ----RGRPRGQPPVPPKPSIRPRPGSL----RSKPEPPSEDLGSLHPGALLFRAS-GHPP 583
RGR GQ + K + R G+L R+ + P + H A A GHP
Sbjct: 135 FLWKRGRDNGQ-FLSRKFVLTEREGALKYFNRNDAKEPKAVMKIEHLNATFQPAKIGHP- 192
Query: 584 SLPTMADALAHGADVNWVNGGQDNAT 609
HG V ++ +DN+T
Sbjct: 193 ----------HGLQVTYL---KDNST 205
>gi|208022687 GTPase regulator associated with the focal adhesion
kinase pp125 isoform b [Homo sapiens]
Length = 759
Score = 93.2 bits (230), Expect = 8e-19
Identities = 77/374 (20%), Positives = 161/374 (43%), Gaps = 38/374 (10%)
Query: 5 LDFEECLKDSPRFRASIELVEAEVSELETRLEKLLKLGTGLLESGRHYLAASRAFVVGI- 63
L+F +C DSP FR +++ EAE+ + +++L+K G L+ + ++ +A R F +
Sbjct: 6 LEFSDCCLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKFADSLN 65
Query: 64 -----CDLARLGPPEPMMAECLEKFTVSLNHKLDSHAELLDATQHTLQQQIQTLVKEGLR 118
C E +A L++F L + D +++ L ++ KE +
Sbjct: 66 EFKFQCIGDAETDDEMCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFRKEQIG 125
Query: 119 GFREARRDFWRGAESLEAALTHNAEV-PRRRAQEAEEAGAALRTARAGYRGRALDYALQI 177
+EA++ + + E L + + +++ + +EA + + R + +L+Y ++
Sbjct: 126 AAKEAKKKYDKETEKYCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLEYVFKV 185
Query: 178 NVIEDKRKFDIMEFVLRLVEAQATHFQQGHEELSRLSQYRKELGAQLHQLVLNSAREKRD 237
+++++ F+ +E +L ++ T + G+E ++ +L + + +
Sbjct: 186 QEVQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFEGTRSE 245
Query: 238 MEQRHVLLKQKELGGEEPEPSLREGPGGLVMEGHLFKRASNAFKT-WSRRWFTIQSNQLV 296
+E +K+ L + P MEG+L+ + F T W + + T
Sbjct: 246 VESLMKKMKENPLEHKTISP--------YTMEGYLYVQEKRHFGTSWVKHYCT------- 290
Query: 297 YQKKYKDPVTVVVDD-------------LRLCTVKLCPDSERRFCFEVVSTSKS--CLLQ 341
YQ+ K V D L+ CT + E+RFCF+V + + +Q
Sbjct: 291 YQRDSKQITMVPFDQKSGGKGGEDESVILKSCTRRKTDSIEKRFCFDVEAVDRPGVITMQ 350
Query: 342 ADSERLLQLWVSAV 355
A SE +LW+ A+
Sbjct: 351 ALSEEDRRLWMEAM 364
>gi|7662208 GTPase regulator associated with the focal adhesion
kinase pp125 isoform a [Homo sapiens]
Length = 814
Score = 93.2 bits (230), Expect = 8e-19
Identities = 77/374 (20%), Positives = 161/374 (43%), Gaps = 38/374 (10%)
Query: 5 LDFEECLKDSPRFRASIELVEAEVSELETRLEKLLKLGTGLLESGRHYLAASRAFVVGI- 63
L+F +C DSP FR +++ EAE+ + +++L+K G L+ + ++ +A R F +
Sbjct: 6 LEFSDCCLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKFADSLN 65
Query: 64 -----CDLARLGPPEPMMAECLEKFTVSLNHKLDSHAELLDATQHTLQQQIQTLVKEGLR 118
C E +A L++F L + D +++ L ++ KE +
Sbjct: 66 EFKFQCIGDAETDDEMCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFRKEQIG 125
Query: 119 GFREARRDFWRGAESLEAALTHNAEV-PRRRAQEAEEAGAALRTARAGYRGRALDYALQI 177
+EA++ + + E L + + +++ + +EA + + R + +L+Y ++
Sbjct: 126 AAKEAKKKYDKETEKYCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLEYVFKV 185
Query: 178 NVIEDKRKFDIMEFVLRLVEAQATHFQQGHEELSRLSQYRKELGAQLHQLVLNSAREKRD 237
+++++ F+ +E +L ++ T + G+E ++ +L + + +
Sbjct: 186 QEVQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFEGTRSE 245
Query: 238 MEQRHVLLKQKELGGEEPEPSLREGPGGLVMEGHLFKRASNAFKT-WSRRWFTIQSNQLV 296
+E +K+ L + P MEG+L+ + F T W + + T
Sbjct: 246 VESLMKKMKENPLEHKTISP--------YTMEGYLYVQEKRHFGTSWVKHYCT------- 290
Query: 297 YQKKYKDPVTVVVDD-------------LRLCTVKLCPDSERRFCFEVVSTSKS--CLLQ 341
YQ+ K V D L+ CT + E+RFCF+V + + +Q
Sbjct: 291 YQRDSKQITMVPFDQKSGGKGGEDESVILKSCTRRKTDSIEKRFCFDVEAVDRPGVITMQ 350
Query: 342 ADSERLLQLWVSAV 355
A SE +LW+ A+
Sbjct: 351 ALSEEDRRLWMEAM 364
>gi|21264558 stromal membrane-associated GTPase-activating protein 1
isoform B [Homo sapiens]
Length = 440
Score = 93.2 bits (230), Expect = 8e-19
Identities = 59/202 (29%), Positives = 101/202 (50%), Gaps = 21/202 (10%)
Query: 407 VVAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWE 466
+++++ + N C DC P WAS N+GV +CI+C+GIHR+LGVH S+V+S+ LD W
Sbjct: 20 ILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWT 79
Query: 467 PELVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLTK---- 522
E ++ M ++GN +YEA + ++P + Q E +I KY +KK+ K
Sbjct: 80 AEQIQCMQDMGNTKARLLYEANLPE-NFRRPQ---TDQAVEFFIRDKYEKKKYYDKNAIA 135
Query: 523 -LPEIRGRRGGRGRPRGQPPVPPKP-----------SIRPRPGSLRSKPEPPSEDLGSLH 570
+ + ++ + +P P KP + P+ + K P+ DL L
Sbjct: 136 ITNKEKEKKKEEKKREKEPEKPAKPLTAEKLQKKDQQLEPKKSTSPKKAAEPTVDLLGLD 195
Query: 571 PGALLFRASGHPPSLPTMADAL 592
A+ +G+ ++P + D L
Sbjct: 196 GPAVAPVTNGN-TTVPPLNDDL 216
>gi|21264592 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain
2 [Homo sapiens]
Length = 1704
Score = 91.3 bits (225), Expect = 3e-18
Identities = 93/351 (26%), Positives = 139/351 (39%), Gaps = 94/351 (26%)
Query: 288 FTIQSNQLVY----QKKYKDPVTVVVDDLRLCTVKLCPDSERRFCFEVVSTSKSCLLQAD 343
FT+ S V+ ++ +K + + + + + VK D + FE+++ +S A+
Sbjct: 604 FTVLSGNSVWLCKNEQDFKSGLGITIIPMNVANVKQV-DRTVKQSFEIITPYRSFSFTAE 662
Query: 344 SERLLQLWVSAVQSSIASAFSQARLDDSPRGPGQGSGHLAIGSAATLGSGGMARGREPGG 403
+E+ Q W+ AVQ SIA S
Sbjct: 663 TEKEKQDWIEAVQQSIAETLSDYE------------------------------------ 686
Query: 404 VGHVVAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLD 463
V ++ + N C DC+ P P+WASINL V +C +C+G HRSLG SKVRSL +D
Sbjct: 687 ---VAEKIWFNESNRSCADCKAPDPDWASINLCVVICKKCAGQHRSLGPKDSKVRSLKMD 743
Query: 464 S--WEPELVKLMCELGNVIINQIYEARV---EAMAVKKPGPSCSRQEKEAWIHAKYVEKK 518
+ W EL++L +GN N + + E + + P ++++ +I KY E K
Sbjct: 744 ASIWSNELIELFIVIGNKRANDFWAGNLQKDEELHMDSP-----VEKRKNFITQKYKEGK 798
Query: 519 FLTKLPEIRGRRGGRGRPRGQPPVPPKPSIRPRPGSLRSKPEPPSEDLGSLHPGALLFRA 578
F R L S + E+L L A
Sbjct: 799 F-------------------------------RKTLLASLTK---EELNK-----ALCAA 819
Query: 579 SGHPPSLPTMADALAHGADVNWVNGGQDNATPLIQATAANSLLACEFLLQN 629
P L TMA L GADV G ++TP + A A L EFL N
Sbjct: 820 VVKPDVLETMA-LLFSGADVMCATGDPVHSTPYLLAKKAGQSLQMEFLYHN 869
Score = 30.4 bits (67), Expect = 6.2
Identities = 21/96 (21%), Positives = 45/96 (46%), Gaps = 5/96 (5%)
Query: 267 VMEGHLFKRASNAFKTWSRRWFTIQSNQLVYQKKYKDPVTVVVDDLR-LCTVKLCPDSER 325
V G L K + + + +RW + Y K+ + + L + TV++ D++
Sbjct: 484 VKSGWLDKLSPQGKRMFQKRWVKFDGLSISYYNNEKEMYSKGIIPLSAISTVRVQGDNK- 542
Query: 326 RFCFEVVSTSKSCLLQADSERLLQLWVSAVQSSIAS 361
FEVV+T ++ + + + E W+S + +++ S
Sbjct: 543 ---FEVVTTQRTFVFRVEKEEERNDWISILLNALKS 575
>gi|113204622 stromal membrane-associated GTPase-activating protein
1 isoform A [Homo sapiens]
Length = 467
Score = 91.3 bits (225), Expect = 3e-18
Identities = 44/116 (37%), Positives = 70/116 (60%), Gaps = 4/116 (3%)
Query: 407 VVAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWE 466
+++++ + N C DC P WAS N+GV +CI+C+GIHR+LGVH S+V+S+ LD W
Sbjct: 20 ILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWT 79
Query: 467 PELVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLTK 522
E ++ M ++GN +YEA + ++P + Q E +I KY +KK+ K
Sbjct: 80 AEQIQCMQDMGNTKARLLYEANLPE-NFRRPQ---TDQAVEFFIRDKYEKKKYYDK 131
>gi|206725422 G protein-coupled receptor kinase interacting ArfGAP 2
isoform 5 [Homo sapiens]
Length = 729
Score = 87.8 bits (216), Expect = 3e-17
Identities = 83/324 (25%), Positives = 136/324 (41%), Gaps = 57/324 (17%)
Query: 420 CCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWEPELVKLMCELGNV 479
C DC P P WAS+N G LC +C +HRSLG H S+VR L W P L++++ L N
Sbjct: 11 CADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQMVETLYNN 70
Query: 480 IINQIYE-ARVEAMAVKKPGPSCSRQE-----KEAWIHAKYVEKKFLTKLPEIRGRRGGR 533
N I+E + ++ ++ + Q+ K +I AKY F+ +LP
Sbjct: 71 GANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLP--------- 121
Query: 534 GRPRGQPPVPPKPSIRPRPGSLRSKPEPPSEDLG-SLHPGALLFRASGHPPSLPTMADAL 592
R ++DL LH +S +L T L
Sbjct: 122 ---------------------CRDDDSVTAKDLSKQLH-------SSVRTGNLETCLRLL 153
Query: 593 AHGADVNWVNGGQDNATPLIQATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILGH 652
+ GA N+ + + N TPL A+ A +L E L GA+ DS+G+ P+ +A GH
Sbjct: 154 SLGAQANFFHPEKGN-TPLHVASKAGQILQAELLAVYGADPGTQDSSGKTPVDYARQGGH 212
Query: 653 TGLACLFLKRGADLGAR-----------DSEGRDPLTIAMETANADIVTLLRLAKMREAE 701
LA ++ +L R G+ + M ++ D+ L + AK ++ +
Sbjct: 213 HELAERLVEIQYELTDRLAFYLCGRKPDHKNGQHFIIPQMADSSLDLSELAKAAK-KKLQ 271
Query: 702 AAQGQAGDETYLDIFRDFSLMASD 725
+ +E +D++ + +D
Sbjct: 272 SLSNHLFEELAMDVYDEVDRRETD 295
>gi|21237786 G protein-coupled receptor kinase interacting ArfGAP 2
isoform 3 [Homo sapiens]
Length = 679
Score = 87.8 bits (216), Expect = 3e-17
Identities = 83/324 (25%), Positives = 136/324 (41%), Gaps = 57/324 (17%)
Query: 420 CCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWEPELVKLMCELGNV 479
C DC P P WAS+N G LC +C +HRSLG H S+VR L W P L++++ L N
Sbjct: 11 CADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQMVETLYNN 70
Query: 480 IINQIYE-ARVEAMAVKKPGPSCSRQE-----KEAWIHAKYVEKKFLTKLPEIRGRRGGR 533
N I+E + ++ ++ + Q+ K +I AKY F+ +LP
Sbjct: 71 GANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLP--------- 121
Query: 534 GRPRGQPPVPPKPSIRPRPGSLRSKPEPPSEDLG-SLHPGALLFRASGHPPSLPTMADAL 592
R ++DL LH +S +L T L
Sbjct: 122 ---------------------CRDDDSVTAKDLSKQLH-------SSVRTGNLETCLRLL 153
Query: 593 AHGADVNWVNGGQDNATPLIQATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILGH 652
+ GA N+ + + N TPL A+ A +L E L GA+ DS+G+ P+ +A GH
Sbjct: 154 SLGAQANFFHPEKGN-TPLHVASKAGQILQAELLAVYGADPGTQDSSGKTPVDYARQGGH 212
Query: 653 TGLACLFLKRGADLGAR-----------DSEGRDPLTIAMETANADIVTLLRLAKMREAE 701
LA ++ +L R G+ + M ++ D+ L + AK ++ +
Sbjct: 213 HELAERLVEIQYELTDRLAFYLCGRKPDHKNGQHFIIPQMADSSLDLSELAKAAK-KKLQ 271
Query: 702 AAQGQAGDETYLDIFRDFSLMASD 725
+ +E +D++ + +D
Sbjct: 272 SLSNHLFEELAMDVYDEVDRRETD 295
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,319,734
Number of Sequences: 37866
Number of extensions: 1551785
Number of successful extensions: 11989
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 381
Number of HSP's successfully gapped in prelim test: 255
Number of HSP's that attempted gapping in prelim test: 9477
Number of HSP's gapped (non-prelim): 2393
length of query: 740
length of database: 18,247,518
effective HSP length: 110
effective length of query: 630
effective length of database: 14,082,258
effective search space: 8871822540
effective search space used: 8871822540
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.