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Search of human proteins with 7661556
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7661556 TruB pseudouridine (psi) synthase homolog 2 [Homo
sapiens]
(331 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7661556 TruB pseudouridine (psi) synthase homolog 2 [Homo sap... 667 0.0
gi|21040257 TruB pseudouridine (psi) synthase homolog 1 [Homo sa... 112 5e-25
gi|222537745 schlafen family member 12-like [Homo sapiens] 32 1.0
gi|239750217 PREDICTED: hypothetical protein [Homo sapiens] 30 2.3
gi|239744524 PREDICTED: hypothetical protein XP_002343168 [Homo ... 30 2.3
gi|11119430 testis-specific kinase substrate [Homo sapiens] 30 3.9
gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [... 29 5.1
gi|19923669 sel-1 suppressor of lin-12-like [Homo sapiens] 29 6.6
gi|44888833 PDZ domain containing 6 [Homo sapiens] 29 6.6
gi|239755705 PREDICTED: hypothetical protein [Homo sapiens] 28 8.7
gi|187761351 growth factor independent 1 [Homo sapiens] 28 8.7
gi|187761349 growth factor independent 1 [Homo sapiens] 28 8.7
gi|71037377 growth factor independent 1 [Homo sapiens] 28 8.7
gi|209915556 cyclin D3 isoform 4 [Homo sapiens] 28 8.7
gi|209862835 cyclin D3 isoform 1 [Homo sapiens] 28 8.7
gi|209915553 cyclin D3 isoform 3 [Homo sapiens] 28 8.7
gi|4502619 cyclin D3 isoform 2 [Homo sapiens] 28 8.7
>gi|7661556 TruB pseudouridine (psi) synthase homolog 2 [Homo
sapiens]
Length = 331
Score = 667 bits (1722), Expect = 0.0
Identities = 331/331 (100%), Positives = 331/331 (100%)
Query: 1 MGSAGLSRLHGLFAVYKPPGLKWKHLRDTVELQLLKGLNARKPPAPKQRVRFLLGPMEGS 60
MGSAGLSRLHGLFAVYKPPGLKWKHLRDTVELQLLKGLNARKPPAPKQRVRFLLGPMEGS
Sbjct: 1 MGSAGLSRLHGLFAVYKPPGLKWKHLRDTVELQLLKGLNARKPPAPKQRVRFLLGPMEGS 60
Query: 61 EEKELTLTATSVPSFINHPLVCGPAFAHLKVGVGHRLDAQASGVLVLGVGHGCRLLTDMY 120
EEKELTLTATSVPSFINHPLVCGPAFAHLKVGVGHRLDAQASGVLVLGVGHGCRLLTDMY
Sbjct: 61 EEKELTLTATSVPSFINHPLVCGPAFAHLKVGVGHRLDAQASGVLVLGVGHGCRLLTDMY 120
Query: 121 NAHLTKDYTVRGLLGKATDDFREDGRLVEKTTYDHVTREKLDRILAVIQGSHQKALVMYS 180
NAHLTKDYTVRGLLGKATDDFREDGRLVEKTTYDHVTREKLDRILAVIQGSHQKALVMYS
Sbjct: 121 NAHLTKDYTVRGLLGKATDDFREDGRLVEKTTYDHVTREKLDRILAVIQGSHQKALVMYS 180
Query: 181 NLDLKTQEAYEMAVRGLIRPMNKSPMLITGIRCLYFAPPEFLLEVQCMHETQKELRKLVH 240
NLDLKTQEAYEMAVRGLIRPMNKSPMLITGIRCLYFAPPEFLLEVQCMHETQKELRKLVH
Sbjct: 181 NLDLKTQEAYEMAVRGLIRPMNKSPMLITGIRCLYFAPPEFLLEVQCMHETQKELRKLVH 240
Query: 241 EIGLELKTTAVCTQVRRTRDGFFTLDSALLRTQWDLTNIQDAIRAATPQVAAELEKSLSP 300
EIGLELKTTAVCTQVRRTRDGFFTLDSALLRTQWDLTNIQDAIRAATPQVAAELEKSLSP
Sbjct: 241 EIGLELKTTAVCTQVRRTRDGFFTLDSALLRTQWDLTNIQDAIRAATPQVAAELEKSLSP 300
Query: 301 GLDTKQLPSPGWSWDSQGPSSTLGLERGAGQ 331
GLDTKQLPSPGWSWDSQGPSSTLGLERGAGQ
Sbjct: 301 GLDTKQLPSPGWSWDSQGPSSTLGLERGAGQ 331
>gi|21040257 TruB pseudouridine (psi) synthase homolog 1 [Homo
sapiens]
Length = 349
Score = 112 bits (280), Expect = 5e-25
Identities = 92/306 (30%), Positives = 140/306 (45%), Gaps = 42/306 (13%)
Query: 6 LSRLHGLFAVYKPPGLKWKHLRDTVELQLLKGLNARKPPAPKQRVRFLLGPMEGSEEKEL 65
L L G+FAV+KP G L + ++ +LL P E ++ K+
Sbjct: 65 LLSLSGVFAVHKPKGPTSAELLNRLKEKLLAEAGMPSP--------------EWTKRKKQ 110
Query: 66 TLTATSVPSFINHPLVCGPAFAHLKVGVGHRLDAQASGVLVLGVGHGCRLLTDMYNAHLT 125
TL K+G G LD+ A GVLV+G+G G ++LT M + +
Sbjct: 111 TL----------------------KIGHGGTLDSAARGVLVVGIGSGTKMLTSMLSG--S 146
Query: 126 KDYTVRGLLGKATDDFREDGRLVEKTTYDHVTREKLDRILAVIQGSHQKALVMYSNLDLK 185
K YT G LGKATD GR+ E+ YD +T+E ++ IL G+ + +YS L
Sbjct: 147 KRYTAIGELGKATDTLDSTGRVTEEKPYDKITQEDIEGILQKFTGNIMQVPPLYSALKKD 206
Query: 186 TQEAYEMAVRG-LIRPMNKSPMLITGIRCLYFAPPEFLLEVQCMHETQKELRKLVHEIGL 244
Q + RG ++ P+ + I F PP F L+V+C +R LV +IG
Sbjct: 207 GQRLSTLMKRGEVVEAKPARPVTVYSISLQKFQPPFFTLDVECGGGFY--IRSLVSDIGK 264
Query: 245 ELKTTAVCTQVRRTRDGFFTLDS-ALLRTQWDLTNIQDAIRAATPQVAAELEKSLSPGLD 303
EL + A ++ RT+ G FTL+ AL +W + +I ++ + AEL S
Sbjct: 265 ELSSCANVLELTRTKQGPFTLEEHALPEDKWTIDDIAQSLEHCSSLFPAELALKKSKPES 324
Query: 304 TKQLPS 309
+Q+ S
Sbjct: 325 NEQVLS 330
>gi|222537745 schlafen family member 12-like [Homo sapiens]
Length = 617
Score = 31.6 bits (70), Expect = 1.0
Identities = 35/147 (23%), Positives = 65/147 (44%), Gaps = 18/147 (12%)
Query: 159 EKLDRILAVIQGSHQKALVMYS---NLDLKTQEAYEMAVRGLIRPMNKSPMLITGIRCLY 215
E L +++ GS K +++S +LDL QE +++ L+ +K P+L T +
Sbjct: 452 EGLKQLICEEMGSVNKGSLIFSRSWSLDLGLQENHKVLCDALLISQDKPPVLYT----FH 507
Query: 216 FAPPEFLLEVQCMHETQKELRKLVHEIGLELKTTAVCTQVRRTRDGFFTLDSALLRTQWD 275
E + +T + L++ + +IG K V T++ F+ Q+D
Sbjct: 508 MVQDEEFKDYST--QTAQTLKQKLAKIGGYTKKVCVMTKI------FYLSPEGKTSCQYD 559
Query: 276 LTN---IQDAIRAATPQVAAELEKSLS 299
L + ++ T Q +LEK+LS
Sbjct: 560 LNSQVIYPESYYWTTAQTMKDLEKALS 586
>gi|239750217 PREDICTED: hypothetical protein [Homo sapiens]
Length = 363
Score = 30.4 bits (67), Expect = 2.3
Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Query: 36 KGLNARKPPAPKQRVRFLLGPMEGSEEKELTLTATSVPSF--INHPLVCGPAFAHLKVGV 93
+G AR+ PAP + L E TS P F L+C + G+
Sbjct: 159 EGRPARRRPAPAPPLLPLPSRALWLGEWRRGRLGTSRPEFKCYQRQLICSGLRFRVLCGI 218
Query: 94 GHRLDAQASGVLVLGVGHGCRLLT 117
G +D + + L G+G GC L+
Sbjct: 219 GRSVDGEGAAALWHGLGRGCLALS 242
>gi|239744524 PREDICTED: hypothetical protein XP_002343168 [Homo
sapiens]
Length = 363
Score = 30.4 bits (67), Expect = 2.3
Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Query: 36 KGLNARKPPAPKQRVRFLLGPMEGSEEKELTLTATSVPSF--INHPLVCGPAFAHLKVGV 93
+G AR+ PAP + L E TS P F L+C + G+
Sbjct: 159 EGRPARRRPAPAPPLLPLPSRALWLGEWRRGRLGTSRPEFKCYQRQLICSGLRFRVLCGI 218
Query: 94 GHRLDAQASGVLVLGVGHGCRLLT 117
G +D + + L G+G GC L+
Sbjct: 219 GRSVDGEGAAALWHGLGRGCLALS 242
>gi|11119430 testis-specific kinase substrate [Homo sapiens]
Length = 592
Score = 29.6 bits (65), Expect = 3.9
Identities = 35/166 (21%), Positives = 61/166 (36%), Gaps = 39/166 (23%)
Query: 158 REKLDRILAVIQGSHQKALVMYSNLDLKTQEAYEMAVRGLIRPMNKSPMLITGIRCLYFA 217
+EK +R+ +Q + V+ NL+ + QEA E
Sbjct: 151 KEKTNRVNQHVQSLQSECSVLSENLERRRQEAEE-------------------------- 184
Query: 218 PPEFLLEVQCMHETQKELRKLVHEIGLELKTTAVCTQVRRTRDGFFTLDSALLRTQW-DL 276
LE C+ +L++ ++ ++ + T V + L+ Q D
Sbjct: 185 -----LEGYCI-----QLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDE 234
Query: 277 TNIQDAIRAATPQVAAELEKSLSPGLDTKQLPSPGWSWDSQGPSST 322
T + P+ E E+ P + KQ P G SW+S GP++T
Sbjct: 235 TPRRQEAELQEPEEKQEPEEKQEP--EEKQKPEAGLSWNSLGPAAT 278
>gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [Homo
sapiens]
Length = 2564
Score = 29.3 bits (64), Expect = 5.1
Identities = 19/73 (26%), Positives = 37/73 (50%)
Query: 225 VQCMHETQKELRKLVHEIGLELKTTAVCTQVRRTRDGFFTLDSALLRTQWDLTNIQDAIR 284
V+ + + ++E+ ++ L+ V QVR R + A QW L+ ++ A++
Sbjct: 973 VELVEQRKEEMSAVLLVENHVLEVAEVRAQVREKRRAVESAPRAGGALQWRLSGLEAALQ 1032
Query: 285 AATPQVAAELEKS 297
A P+ AA LE++
Sbjct: 1033 ALEPRQAALLEEA 1045
>gi|19923669 sel-1 suppressor of lin-12-like [Homo sapiens]
Length = 794
Score = 28.9 bits (63), Expect = 6.6
Identities = 14/25 (56%), Positives = 16/25 (64%)
Query: 136 KATDDFREDGRLVEKTTYDHVTREK 160
+ T D REDGRL TTYD+ EK
Sbjct: 140 ECTSDGREDGRLWCATTYDYKADEK 164
>gi|44888833 PDZ domain containing 6 [Homo sapiens]
Length = 942
Score = 28.9 bits (63), Expect = 6.6
Identities = 37/164 (22%), Positives = 70/164 (42%), Gaps = 13/164 (7%)
Query: 156 VTREKLDRILAVIQGSHQKALVMYSNLDLKTQEAYEMAVRGLIRPMNKSPML----ITGI 211
VT E ++R+L+ I G Q L + D+K + ++ + + +L + GI
Sbjct: 239 VTTENIERVLSCIPGPMQVKLTFENAYDVKRETSHPRQKKTQSNTSDLVKLLWGEEVEGI 298
Query: 212 RCLYFAPPEFL--LEVQCMHETQKELRKLVHEIGLELKTTAVCTQVRRTRDGFFTLDSAL 269
+ P + L +Q ET KE +++++ + + +++ R F TL L
Sbjct: 299 QQSGLNTPHIIMYLTLQLDSETSKEEQEILYHYPM----SEASQKLKSVRGIFLTLCDML 354
Query: 270 LR-TQWDLTNIQDAIRAATPQVA--AELEKSLSPGLDTKQLPSP 310
T +T+ + VA E +K L GL +++P P
Sbjct: 355 ENVTGTQVTSSSLLLNGKQIHVAYWKESDKLLLIGLPAEEVPLP 398
>gi|239755705 PREDICTED: hypothetical protein [Homo sapiens]
Length = 306
Score = 28.5 bits (62), Expect = 8.7
Identities = 15/50 (30%), Positives = 23/50 (46%), Gaps = 2/50 (4%)
Query: 70 TSVPSF--INHPLVCGPAFAHLKVGVGHRLDAQASGVLVLGVGHGCRLLT 117
TS P F L+C + G+G +D + + L G+G GC L+
Sbjct: 218 TSRPEFKCYQRQLICSGLRFRVLCGIGRSVDGEGAAALWHGLGRGCLALS 267
>gi|187761351 growth factor independent 1 [Homo sapiens]
Length = 422
Score = 28.5 bits (62), Expect = 8.7
Identities = 21/67 (31%), Positives = 27/67 (40%), Gaps = 13/67 (19%)
Query: 277 TNIQDAIRAATPQVAAELEKSLSPGLDTKQ---LPSPGWSWDSQGPSSTL---------- 323
+ +D R +P + EKS+ P LD Q LP +SW S
Sbjct: 84 SEFEDFWRPPSPSASPASEKSMCPSLDEAQPFPLPFKPYSWSGLAGSDLRHLVQSYRPCG 143
Query: 324 GLERGAG 330
LERGAG
Sbjct: 144 ALERGAG 150
>gi|187761349 growth factor independent 1 [Homo sapiens]
Length = 422
Score = 28.5 bits (62), Expect = 8.7
Identities = 21/67 (31%), Positives = 27/67 (40%), Gaps = 13/67 (19%)
Query: 277 TNIQDAIRAATPQVAAELEKSLSPGLDTKQ---LPSPGWSWDSQGPSSTL---------- 323
+ +D R +P + EKS+ P LD Q LP +SW S
Sbjct: 84 SEFEDFWRPPSPSASPASEKSMCPSLDEAQPFPLPFKPYSWSGLAGSDLRHLVQSYRPCG 143
Query: 324 GLERGAG 330
LERGAG
Sbjct: 144 ALERGAG 150
>gi|71037377 growth factor independent 1 [Homo sapiens]
Length = 422
Score = 28.5 bits (62), Expect = 8.7
Identities = 21/67 (31%), Positives = 27/67 (40%), Gaps = 13/67 (19%)
Query: 277 TNIQDAIRAATPQVAAELEKSLSPGLDTKQ---LPSPGWSWDSQGPSSTL---------- 323
+ +D R +P + EKS+ P LD Q LP +SW S
Sbjct: 84 SEFEDFWRPPSPSASPASEKSMCPSLDEAQPFPLPFKPYSWSGLAGSDLRHLVQSYRPCG 143
Query: 324 GLERGAG 330
LERGAG
Sbjct: 144 ALERGAG 150
>gi|209915556 cyclin D3 isoform 4 [Homo sapiens]
Length = 96
Score = 28.5 bits (62), Expect = 8.7
Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
Query: 281 DAIRAATPQVAAELEKSLSPGLDTKQLPSP--GWSWDSQGPSST 322
D +RA Q+ A L +SL T P+P SQGPS T
Sbjct: 42 DCLRACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQT 85
>gi|209862835 cyclin D3 isoform 1 [Homo sapiens]
Length = 211
Score = 28.5 bits (62), Expect = 8.7
Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
Query: 281 DAIRAATPQVAAELEKSLSPGLDTKQLPSP--GWSWDSQGPSST 322
D +RA Q+ A L +SL T P+P SQGPS T
Sbjct: 157 DCLRACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQT 200
>gi|209915553 cyclin D3 isoform 3 [Homo sapiens]
Length = 220
Score = 28.5 bits (62), Expect = 8.7
Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
Query: 281 DAIRAATPQVAAELEKSLSPGLDTKQLPSP--GWSWDSQGPSST 322
D +RA Q+ A L +SL T P+P SQGPS T
Sbjct: 166 DCLRACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQT 209
>gi|4502619 cyclin D3 isoform 2 [Homo sapiens]
Length = 292
Score = 28.5 bits (62), Expect = 8.7
Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
Query: 281 DAIRAATPQVAAELEKSLSPGLDTKQLPSP--GWSWDSQGPSST 322
D +RA Q+ A L +SL T P+P SQGPS T
Sbjct: 238 DCLRACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQT 281
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,309,295
Number of Sequences: 37866
Number of extensions: 593668
Number of successful extensions: 1539
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1529
Number of HSP's gapped (non-prelim): 20
length of query: 331
length of database: 18,247,518
effective HSP length: 103
effective length of query: 228
effective length of database: 14,347,320
effective search space: 3271188960
effective search space used: 3271188960
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.