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Search of human proteins with 7657619
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7657619 sushi-repeat-containing protein, X-linked 2 [Homo
sapiens]
(465 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7657619 sushi-repeat-containing protein, X-linked 2 [Homo sap... 982 0.0
gi|5454086 sushi-repeat-containing protein, X-linked [Homo sapiens] 439 e-123
gi|157419154 selectin P precursor [Homo sapiens] 93 4e-19
gi|187960042 selectin E precursor [Homo sapiens] 89 8e-18
gi|148886654 polydom [Homo sapiens] 87 3e-17
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] 77 3e-14
gi|54792123 complement component (3d/Epstein Barr virus) recepto... 74 2e-13
gi|38045915 pregnancy-associated plasma protein A preproprotein ... 74 3e-13
gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens] 73 5e-13
gi|42544177 complement component (3d/Epstein Barr virus) recepto... 73 6e-13
gi|41152076 steroid-sensitive protein 1 [Homo sapiens] 70 5e-12
gi|41152074 steroid-sensitive protein 1 [Homo sapiens] 70 5e-12
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap... 68 2e-11
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa... 68 2e-11
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap... 68 2e-11
gi|4506875 selectin L precursor [Homo sapiens] 61 2e-09
gi|62912468 complement component 4 binding protein, beta chain i... 58 2e-08
gi|62912466 complement component 4 binding protein, beta chain i... 58 2e-08
gi|62912464 complement component 4 binding protein, beta chain i... 58 2e-08
gi|62912462 complement component 4 binding protein, beta chain i... 58 2e-08
gi|4502505 complement component 4 binding protein, beta chain is... 58 2e-08
gi|86793109 complement receptor 1 isoform S precursor [Homo sapi... 58 2e-08
gi|86793036 complement receptor 1 isoform F precursor [Homo sapi... 58 2e-08
gi|67782358 complement factor B preproprotein [Homo sapiens] 57 4e-08
gi|14550407 complement component 2 isoform 1 preproprotein [Homo... 56 8e-08
gi|153266841 apolipoprotein H precursor [Homo sapiens] 55 2e-07
gi|148922949 complement component (3b/4b) receptor 1-like [Homo ... 54 3e-07
gi|168693643 decay accelerating factor for complement isoform 2 ... 52 1e-06
gi|10835143 decay accelerating factor for complement isoform 1 p... 52 1e-06
gi|27502421 CD46 antigen, complement regulatory protein isoform ... 51 2e-06
>gi|7657619 sushi-repeat-containing protein, X-linked 2 [Homo
sapiens]
Length = 465
Score = 982 bits (2538), Expect = 0.0
Identities = 465/465 (100%), Positives = 465/465 (100%)
Query: 1 MASQLTQRGALFLLFFLTPAVTPTWYAGSGYYPDESYNEVYAEEVPQAPALDYRVPRWCY 60
MASQLTQRGALFLLFFLTPAVTPTWYAGSGYYPDESYNEVYAEEVPQAPALDYRVPRWCY
Sbjct: 1 MASQLTQRGALFLLFFLTPAVTPTWYAGSGYYPDESYNEVYAEEVPQAPALDYRVPRWCY 60
Query: 61 TLNIQDGEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTAYCRQM 120
TLNIQDGEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTAYCRQM
Sbjct: 61 TLNIQDGEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTAYCRQM 120
Query: 121 RCHALPFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDID 180
RCHALPFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDID
Sbjct: 121 RCHALPFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDID 180
Query: 181 PPKIRCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIR 240
PPKIRCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIR
Sbjct: 181 PPKIRCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIR 240
Query: 241 YTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQG 300
YTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQG
Sbjct: 241 YTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQG 300
Query: 301 TPSRVCQSSRQWSGSPPICAPMKINVNVNSAAGLLDQFYEKQRLLIISAPDPSNRYYKMQ 360
TPSRVCQSSRQWSGSPPICAPMKINVNVNSAAGLLDQFYEKQRLLIISAPDPSNRYYKMQ
Sbjct: 301 TPSRVCQSSRQWSGSPPICAPMKINVNVNSAAGLLDQFYEKQRLLIISAPDPSNRYYKMQ 360
Query: 361 ISMLQQSTCGLDLRHVTIIELVGQPPQEVGRIREQQLSANIIEELRQFQRLTRSYFNMVL 420
ISMLQQSTCGLDLRHVTIIELVGQPPQEVGRIREQQLSANIIEELRQFQRLTRSYFNMVL
Sbjct: 361 ISMLQQSTCGLDLRHVTIIELVGQPPQEVGRIREQQLSANIIEELRQFQRLTRSYFNMVL 420
Query: 421 IDKQGIDRDRYMEPVTPEEIFTFIDDYLLSNQELTQRREQRDICE 465
IDKQGIDRDRYMEPVTPEEIFTFIDDYLLSNQELTQRREQRDICE
Sbjct: 421 IDKQGIDRDRYMEPVTPEEIFTFIDDYLLSNQELTQRREQRDICE 465
>gi|5454086 sushi-repeat-containing protein, X-linked [Homo sapiens]
Length = 464
Score = 439 bits (1129), Expect = e-123
Identities = 207/453 (45%), Positives = 294/453 (64%), Gaps = 8/453 (1%)
Query: 13 LLFFLTPAVTPTW-YAGSGYYPDESYNEVYAEEVPQAPALDYRVPRWCYTLNIQDGEATC 71
LL L V P+ + GSG P E Y+ Y+ WC + ++ G+ C
Sbjct: 17 LLLLLLLRVPPSRSFPGSGDSPLEDDEVGYSHP-------RYKDTPWCSPIKVKYGDVYC 69
Query: 72 YSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTAYCRQMRCHALPFITSG 131
+P+GG Y ++LGTRC++ C +G+ L G + C ++RWS C+Q RC L +G
Sbjct: 70 RAPQGGYYKTALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKVICKQKRCPTLAMPANG 129
Query: 132 TYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSRE 191
+ C +G +SRC+Y CS GY L+G+R+ CM++ WSG CVD++PP+I+CP +E
Sbjct: 130 GFKCVDGAYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPPRIKCPSVKE 189
Query: 192 KMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRA 251
++AEP KLT RV W+ P +D+ADG +T V L+G PGS+FPEG+H I+YT YDRA N+
Sbjct: 190 RIAEPNKLTVRVSWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYTVYDRAENKG 249
Query: 252 SCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQ 311
+CKF VKV+V+RC L P++GY+ C+S GDNYGATCE+ C GGY+ QG+P+RVCQS+
Sbjct: 250 TCKFRVKVRVKRCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLA 309
Query: 312 WSGSPPICAPMKINVNVNSAAGLLDQFYEKQRLLIISAPDPSNRYYKMQISMLQQSTCGL 371
WSG+ P CA M +NV V +AA LLDQFYEK+RLLI+S P N Y++Q+ MLQQ+ CGL
Sbjct: 310 WSGTEPTCAAMNVNVGVRTAAALLDQFYEKRRLLIVSTPTARNLLYRLQLGMLQQAQCGL 369
Query: 372 DLRHVTIIELVGQPPQEVGRIREQQLSANIIEELRQFQRLTRSYFNMVLIDKQGIDRDRY 431
DLRH+T++ELVG P +GRI + + + +LR R+ F+MVL+DK G+D++RY
Sbjct: 370 DLRHITVVELVGVFPTLIGRIGAKIMPPALALQLRLLLRIPLYSFSMVLVDKHGMDKERY 429
Query: 432 MEPVTPEEIFTFIDDYLLSNQELTQRREQRDIC 464
+ V P +F ID + L +E+ + E C
Sbjct: 430 VSLVMPVALFNLIDTFPLRKEEMVLQAEMSQTC 462
>gi|157419154 selectin P precursor [Homo sapiens]
Length = 830
Score = 93.2 bits (230), Expect = 4e-19
Identities = 75/270 (27%), Positives = 111/270 (41%), Gaps = 34/270 (12%)
Query: 62 LNIQDGEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQM 120
L+ Q+G TC P G SS + C+ CD G+ L G + C S RW+ + C +
Sbjct: 514 LSPQNGTMTCVQPLGS---SSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAI 570
Query: 121 RCHALPFITSGTYTC--TNGVL-LDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVC- 176
+C L G+ C T G + S C +SC +G+ LEG + C GRWS P C
Sbjct: 571 KCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCK 630
Query: 177 --VDIDPPKIRCPHSREKMAEPEKLTARVYWDPPLVKDSAD---GTITRVTLRGPEPGSH 231
+ P ++CP + P + T P + G TL G S
Sbjct: 631 GIASLPTPGVQCP----ALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSC 686
Query: 232 FPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDN--YGATCE 289
P G+ +TA A C+ + +C L + + C++ N YG+ C
Sbjct: 687 RPSGQ----WTAVTPA-----CRAV------KCSELHVNKPIAMNCSNLWGNFSYGSICS 731
Query: 290 YHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
+HC G G+ CQ + WS + P C
Sbjct: 732 FHCLEGQLLNGSAQTACQENGHWSTTVPTC 761
Score = 87.4 bits (215), Expect = 2e-17
Identities = 72/287 (25%), Positives = 106/287 (36%), Gaps = 48/287 (16%)
Query: 59 CYTLNIQD------GEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWS 112
C L QD C P G + S+ C +C+ G L+G +QCL + W+
Sbjct: 443 CQALQCQDLPVPNEARVNCSHPFGAFRYQSV---CSFTCNEGLLLVGASVLQCLATGNWN 499
Query: 113 GTA-YCRQMRCHALPFITSGTYTCTNGV---LLDSRCDYSCSSGYHLEGDRSRICMEDGR 168
C+ + C L +GT TC + S C + C GY L G C GR
Sbjct: 500 SVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGR 559
Query: 169 WSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEP 228
W+ P+C I P++ P + S D + TR
Sbjct: 560 WTDSPPMCEAIKCPELFAPE----------------------QGSLDCSDTRGEFNVGST 597
Query: 229 GSHFP-------EGEHVIRYTAYDR-AYNRASCKFIVKVQVR--RCPTLKPPQHGYLTCT 278
HF EG + + T R + +CK I + +CP L P G + C
Sbjct: 598 -CHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCR 656
Query: 279 SAGDNYG--ATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPMK 323
+G TC + C+ G+ G + C+ S QW+ P C +K
Sbjct: 657 HHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVK 703
Score = 81.3 bits (199), Expect = 2e-15
Identities = 65/246 (26%), Positives = 96/246 (39%), Gaps = 37/246 (15%)
Query: 85 TRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTN---GVL 140
T C C GF L G V+C +W+ A C+ ++C LP C++
Sbjct: 410 TNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFR 469
Query: 141 LDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLT 200
S C ++C+ G L G C+ G W+ P C I + P +
Sbjct: 470 YQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQN----------- 518
Query: 201 ARVYWDPPLVKDSADGTITRV-----TLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKF 255
+ PL S T + +L GPE G R+T + C+
Sbjct: 519 GTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSG----RWTD-----SPPMCEA 569
Query: 256 IVKVQVRRCPTLKPPQHGYLTC--TSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWS 313
I +CP L P+ G L C T N G+TC + CD G+ +G + C +S +WS
Sbjct: 570 I------KCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWS 623
Query: 314 GSPPIC 319
+PP C
Sbjct: 624 ATPPTC 629
Score = 78.2 bits (191), Expect = 1e-14
Identities = 69/269 (25%), Positives = 103/269 (38%), Gaps = 33/269 (12%)
Query: 59 CYTLNIQD-GEATC-YSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA- 115
C L I + G TC +S K + SS C SC+ GF L+G VQC S W+ A
Sbjct: 262 CPPLKIPERGNMTCLHSAKAFQHQSS----CSFSCEEGFALVGPEVVQCTASGVWTAPAP 317
Query: 116 YCRQMRCHALPFITSGTYTCTNGVLL---DSRCDYSCSSGYHLEGDRSRICMEDGRWSGG 172
C+ ++C L + GT C + + S C + C GY + G C++ G WS
Sbjct: 318 VCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAP 377
Query: 173 EPVCVDIDPPKIRCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHF 232
P C I + P P L A Y D A+G + R G+
Sbjct: 378 LPTCEAISCEPLESPVHGSMDCSP-SLRAFQY-DTNCSFRCAEGFMLR--------GADI 427
Query: 233 PEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTS--AGDNYGATCEY 290
+++ ++TA Q +C L P + C+ Y + C +
Sbjct: 428 VRCDNLGQWTAPAPV-----------CQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSF 476
Query: 291 HCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
C+ G G C ++ W+ PP C
Sbjct: 477 TCNEGLLLVGASVLQCLATGNWNSVPPEC 505
Score = 71.2 bits (173), Expect = 2e-12
Identities = 60/253 (23%), Positives = 96/253 (37%), Gaps = 29/253 (11%)
Query: 77 GNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTC 135
GN+ S ++C C G+++ G ++CL S W+ C +C L G TC
Sbjct: 218 GNF--SFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTC 275
Query: 136 TNGVLL---DSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREK 192
+ S C +SC G+ L G C G W+ PVC + + P S
Sbjct: 276 LHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQCQHLEAP-SEGT 334
Query: 193 MAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRAS 252
M LTA Y G+ + +PG G ++R D + A
Sbjct: 335 MDCVHPLTAFAY-----------GSSCKFEC---QPGYRV-RGLDMLR--CIDSGHWSAP 377
Query: 253 CKFIVKVQVRRCPTLKPPQHGYLTCTSA--GDNYGATCEYHCDGGYDRQGTPSRVCQSSR 310
+ + C L+ P HG + C+ + Y C + C G+ +G C +
Sbjct: 378 ---LPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLG 434
Query: 311 QWSGSPPICAPMK 323
QW+ P+C ++
Sbjct: 435 QWTAPAPVCQALQ 447
Score = 57.4 bits (137), Expect = 3e-08
Identities = 67/309 (21%), Positives = 109/309 (35%), Gaps = 44/309 (14%)
Query: 34 DESYNEVYAEEVPQAPALDYRVPRWCYTLNIQDGEATCYSPKGGNYHSSLGTRCELSCDR 93
+E E+Y + P AP +W ++ A CY+ + S C
Sbjct: 128 NEDCVEIYIKS-PSAPG------KWNDEHCLKKKHALCYTASCQDMSCSKQGEC------ 174
Query: 94 GFRLIGRRSVQCLPSRRWSGTAYCRQMRCHALPFITSGTYTCTNGV---LLDSRCDYSCS 150
IG + C P Y R+ C L C++ + +S+C + C+
Sbjct: 175 -LETIGNYTCSCYPGFYGPECEYVRE--CGELELPQHVLMNCSHPLGNFSFNSQCSFHCT 231
Query: 151 SGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTARVYWDPPLV 210
GY + G C+ G W+ P C+ P ++ P E+ +A+ +
Sbjct: 232 DGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIP---ERGNMTCLHSAKAFQHQSSC 288
Query: 211 KDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRAS-CKFIVKVQVRRCPTLKP 269
S + V GPE V++ TA A CK + +C L+
Sbjct: 289 SFSCEEGFALV---GPE----------VVQCTASGVWTAPAPVCKAV------QCQHLEA 329
Query: 270 PQHGYLTCTS--AGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPMKINVN 327
P G + C YG++C++ C GY +G C S WS P C +
Sbjct: 330 PSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPL 389
Query: 328 VNSAAGLLD 336
+ G +D
Sbjct: 390 ESPVHGSMD 398
>gi|187960042 selectin E precursor [Homo sapiens]
Length = 610
Score = 89.0 bits (219), Expect = 8e-18
Identities = 66/283 (23%), Positives = 110/283 (38%), Gaps = 40/283 (14%)
Query: 65 QDGEATCYSPKGG-NYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRC 122
+ G C P G +Y+SS C +SCDRG+ ++QC+ S WS C + C
Sbjct: 187 EHGSLVCSHPLGNFSYNSS----CSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVEC 242
Query: 123 HALPFITSGTYTC---TNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDI 179
A+ +G C ++ C + C G+ L G +S C G W +P C +
Sbjct: 243 DAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAV 302
Query: 180 DPPKIRCPHSREKMAEPEKLTARVYWDPP---LVKDSADGTITR-VTLRGPEPGSHFPEG 235
+R +P+ + R P K S + T L+GP +G
Sbjct: 303 TCRAVR---------QPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQG 353
Query: 236 EHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTC---TSAGDNYGATCEYHC 292
+ + I + +C L P+ GY+ C S YG++CE+ C
Sbjct: 354 QWT---------------QQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSC 398
Query: 293 DGGYDRQGTPSRVCQSSRQWSGSPPICAPMKINVNVNSAAGLL 335
+ G+ +G+ C + +W P C ++ + GL+
Sbjct: 399 EQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLV 441
Score = 82.8 bits (203), Expect = 6e-16
Identities = 70/279 (25%), Positives = 111/279 (39%), Gaps = 32/279 (11%)
Query: 65 QDGEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCH 123
Q+G C G + + + C +C+ GF L G V+C +W+ C +C
Sbjct: 311 QNGSVRCSHSPAGEF--TFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCT 368
Query: 124 ALPFITSGTYTC----TNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDI 179
AL G C + S C++SC G+ L+G + C G W +P C
Sbjct: 369 ALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTC--- 425
Query: 180 DPPKIRCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVI 239
+RC + + +P K R P I T + S EG +
Sbjct: 426 --EAVRC----DAVHQPPKGLVRCAHSP----------IGEFTYKSSCAFS-CEEGFELH 468
Query: 240 RYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQ 299
T + + + QV +C +L P ++C S +G C++ C G+
Sbjct: 469 GSTQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSC-SGEPVFGTVCKFACPEGWTLN 527
Query: 300 GTPSRVCQSSRQWSGSPPIC-APMKINVNV---NSAAGL 334
G+ +R C ++ WSG P C AP + N+ + SAAGL
Sbjct: 528 GSAARTCGATGHWSGLLPTCEAPTESNIPLVAGLSAAGL 566
Score = 78.6 bits (192), Expect = 1e-14
Identities = 62/270 (22%), Positives = 107/270 (39%), Gaps = 33/270 (12%)
Query: 63 NIQDGEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMR 121
N +G C+ G T C C+ GF L+G +S+QC S W C+ +
Sbjct: 247 NPANGFVECFQNPGS---FPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVT 303
Query: 122 CHALPFITSGTYTCTNG----VLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCV 177
C A+ +G+ C++ S C+++C G+ L+G C G+W+ PVC
Sbjct: 304 CRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCE 363
Query: 178 DIDPPKIRCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITR-VTLRGPEPGSHFPEGE 236
+ P P + Y S + + + L+G + P GE
Sbjct: 364 AFQCTALSNPERGYMNCLPSASGSFRY------GSSCEFSCEQGFVLKGSKRLQCGPTGE 417
Query: 237 HVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSA--GD-NYGATCEYHCD 293
+D + +C+ + RC + P G + C + G+ Y ++C + C+
Sbjct: 418 -------WDN--EKPTCEAV------RCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCE 462
Query: 294 GGYDRQGTPSRVCQSSRQWSGSPPICAPMK 323
G++ G+ C S QW+ P C +K
Sbjct: 463 EGFELHGSTQLECTSQGQWTEEVPSCQVVK 492
Score = 55.8 bits (133), Expect = 8e-08
Identities = 53/245 (21%), Positives = 94/245 (38%), Gaps = 29/245 (11%)
Query: 98 IGRRSVQCLPSRRWSGTAYCRQMRCHALPFITSGTYTCTNGV---LLDSRCDYSCSSGYH 154
I + +C P +SG + + C AL G+ C++ + +S C SC GY
Sbjct: 158 INNYTCKCDPG--FSGLKCEQIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYL 215
Query: 155 LEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTARVYWDPPLVKDSA 214
+ CM G WS P C ++ + P + E + W+ D
Sbjct: 216 PSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANG--FVECFQNPGSFPWNTTCTFDCE 273
Query: 215 DGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGY 274
+G L G + G +D + +CK + C ++ PQ+G
Sbjct: 274 EG----FELMGAQSLQCTSSGN-------WDN--EKPTCKAVT------CRAVRQPQNGS 314
Query: 275 LTCTS--AGD-NYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPMKINVNVNSA 331
+ C+ AG+ + ++C + C+ G+ QG C + QW+ P+C + N
Sbjct: 315 VRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPE 374
Query: 332 AGLLD 336
G ++
Sbjct: 375 RGYMN 379
Score = 54.7 bits (130), Expect = 2e-07
Identities = 53/233 (22%), Positives = 81/233 (34%), Gaps = 21/233 (9%)
Query: 114 TAYCRQMRCHALPFITSGTYTCTNGVLLDSRCDY-----SCSSGYHLEGDRSRICMEDGR 168
+AYC+Q H + N +L S Y ++ + G + + E
Sbjct: 37 SAYCQQRYTHLVAIQNKEEIEYLNSILSYSPSYYWIGIRKVNNVWVWVGTQKPLTEEAKN 96
Query: 169 WSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEP 228
W+ GEP D + REK W+
Sbjct: 97 WAPGEPNNRQKDEDCVEIYIKREKDVG--------MWNDERCSKKKLALCYTAACTNTSC 148
Query: 229 GSHFPEGEHVIRYTAY-DRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDN--YG 285
H E + YT D ++ C+ IV C L+ P+HG L C+ N Y
Sbjct: 149 SGHGECVETINNYTCKCDPGFSGLKCEQIVN-----CTALESPEHGSLVCSHPLGNFSYN 203
Query: 286 ATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPMKINVNVNSAAGLLDQF 338
++C CD GY + C SS +WS P C ++ + N A G ++ F
Sbjct: 204 SSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECF 256
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 87.0 bits (214), Expect = 3e-17
Identities = 73/297 (24%), Positives = 117/297 (39%), Gaps = 54/297 (18%)
Query: 84 GTRCELSCDRGFRLIGRRSVQCLPSRRWS-GTAYCRQMRCHALPFITSGTYTCTNGVLLD 142
G + C +GF+L+G + C +WS G +C C +LP I + + T+ +
Sbjct: 3025 GKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPMIPNAFISETSS-WKE 3083
Query: 143 SRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDI---DPP----------------- 182
+ YSC SGY ++G IC E G WS PVC + PP
Sbjct: 3084 NVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPSVANAVATGEAHTYESE 3143
Query: 183 -KIRCPHSREKMAEPEKLTARV--YWDPPLV-----KDSADGTITRVTLRGPE------- 227
K+RC + + T + W P + K IT + + G +
Sbjct: 3144 VKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCPLPENITHILVHGDDFSVNRQV 3203
Query: 228 -----PGSHFPEGEHVIRYT---AYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTS 279
G F EG ++ ++ ++ SC + C + P+HG++
Sbjct: 3204 SVSCAEGYTF-EGVNISVCQLDGTWEPPFSDESCSPV------SCGKPESPEHGFV--VG 3254
Query: 280 AGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPMKINVNVNSAAGLLD 336
+ + +T Y C+ GY+ +G RVCQ +RQWSG IC + + G D
Sbjct: 3255 SKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKETRCETPLEFLNGKAD 3311
Score = 84.3 bits (207), Expect = 2e-16
Identities = 54/183 (29%), Positives = 83/183 (45%), Gaps = 8/183 (4%)
Query: 85 TRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPF---ITSGTYTC-TNGV 139
T C ++CD G+RL G + C + +W G C + C + + C
Sbjct: 460 TTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPA 519
Query: 140 LLDSRCDYSCSSGYHLEGDRSRI-CMEDGRWSGG--EPVCVDIDPPKIRCPHSREKMAEP 196
+ C SC G+ L G + + C G+W+ G VC D++ P+I CP E
Sbjct: 520 KFGTICYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAPQINCPKDIEAKTLE 579
Query: 197 EKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFI 256
++ +A V W P KD++ ++ P FP G+ I YTA D + N+ASC F
Sbjct: 580 QQDSANVTWQIPTAKDNSGEKVSVHVHPAFTPPYLFPIGDVAIVYTATDLSGNQASCIFH 639
Query: 257 VKV 259
+KV
Sbjct: 640 IKV 642
Score = 84.0 bits (206), Expect = 3e-16
Identities = 66/276 (23%), Positives = 110/276 (39%), Gaps = 32/276 (11%)
Query: 84 GTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGVLLD 142
G++ L CD GF+L+G CL +W+ +C ++ C P + +G ++ +
Sbjct: 1651 GSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGVPPPLENGFHSADD-FYAG 1709
Query: 143 SRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTAR 202
S Y C++GY+L GD C ++G W+G P C+D+D + S +
Sbjct: 1710 STVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYI 1769
Query: 203 VYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCK-------- 254
PP + DG ++ PG+ PE H A SC+
Sbjct: 1770 CSCVPPY---TGDGKNCAEPIKCKAPGN--PENGHSSGEIYTVGAEVTFSCQEGYQLMGV 1824
Query: 255 -------------FIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGT 301
I + C P++G + +G+ Y C+ GY G
Sbjct: 1825 TKITCLESGEWNHLIPYCKAVSCGKPAIPENGCI--EELAFTFGSKVTYRCNKGYTLAGD 1882
Query: 302 PSRVCQSSRQWSGSPPICAPMKIN--VNVNSAAGLL 335
C ++ WS SPP+C P+K + N+N+ +L
Sbjct: 1883 KESSCLANSSWSHSPPVCEPVKCSSPENINNGKYIL 1918
Score = 76.3 bits (186), Expect = 6e-14
Identities = 68/262 (25%), Positives = 99/262 (37%), Gaps = 35/262 (13%)
Query: 81 SSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGV 139
+S+G+ + SC G L G CL +R+WSG + C + C + +G+ +N
Sbjct: 2733 TSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYT 2792
Query: 140 LLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKL 199
L S Y C GY L G R C +D W EP+C+ +D P S ++
Sbjct: 2793 YL-STLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSP--PVSANGQVRGDEY 2849
Query: 200 TARVYWDPPLVKDSA-DGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVK 258
T + + + +G +RV L P+ V
Sbjct: 2850 TFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPV-------------------- 2889
Query: 259 VQVRRCPTLKPPQHGYLTCTSAGDNYGATCE--YHCDGGYDRQGTPSRVCQSSRQWSGSP 316
RC T PPQ + G +YG E +HC GY G P CQS W
Sbjct: 2890 ----RCAT--PPQ--LANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEI 2941
Query: 317 PICAPMKINVNVNSAAGLLDQF 338
P+C P+ + A G + F
Sbjct: 2942 PLCKPVNCGPPEDLAHGFPNGF 2963
Score = 73.6 bits (179), Expect = 4e-13
Identities = 73/261 (27%), Positives = 107/261 (40%), Gaps = 39/261 (14%)
Query: 73 SPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWS-GTAYCRQMRCHALPFITSG 131
S KG NY + L T CD G+ L G C + W C + C + P +G
Sbjct: 2785 SIKGSNY-TYLST-LYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANG 2842
Query: 132 TYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSRE 191
+ +Y+C+ G+ LEG RSR+C+ +G WSG P CV + RC
Sbjct: 2843 QVR-GDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPV-----RC----- 2891
Query: 192 KMAEPEKLTARVYWDPPLVKDSAD-GTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNR 250
A P +L V + D G + VT H EG I + A + +
Sbjct: 2892 --ATPPQLANGV-------TEGLDYGFMKEVTF-------HCHEG--YILHGA-PKLTCQ 2932
Query: 251 ASCKFIVKVQVRRCPTLKPPQ---HGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQ 307
+ + ++ + + PP+ HG+ S +G +Y C GY G SR C
Sbjct: 2933 SDGNWDAEIPLCKPVNCGPPEDLAHGFPNGFSF--IHGGHIQYQCFPGYKLHGNSSRRCL 2990
Query: 308 SSRQWSGSPPICAPMKINVNV 328
S+ WSGS P C P + + V
Sbjct: 2991 SNGSWSGSSPSCLPCRCSTPV 3011
Score = 72.0 bits (175), Expect = 1e-12
Identities = 57/231 (24%), Positives = 91/231 (39%), Gaps = 28/231 (12%)
Query: 90 SCDRGFRLIGRRSVQCLPSRRWSGT-AYCRQMRCHALPFITSGTYTCTNGVLLDSRCDYS 148
SC G L G ++CLPS++W+ + C+ + C P I+ G ++ + S YS
Sbjct: 2348 SCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFGVPIPSSALHFGSTVKYS 2407
Query: 149 CSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTARVYWDPP 208
C G+ L G+ + +C DG WS P CV ++ CP +PE++ P
Sbjct: 2408 CVGGFFLRGNSTTLCQPDGTWSSPLPECVPVE-----CP-------QPEEI-------PN 2448
Query: 209 LVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLK 268
+ D L +PG + + +CK I C K
Sbjct: 2449 GIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAI------ECLKPK 2502
Query: 269 PPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
+G + T +YG T Y C+ G+ +G + C + W P C
Sbjct: 2503 EILNGKFSYTDL--HYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSC 2551
Score = 70.9 bits (172), Expect = 2e-12
Identities = 70/301 (23%), Positives = 108/301 (35%), Gaps = 35/301 (11%)
Query: 41 YAEEVPQAPALDYRVPRWCYTLNI--QDGEATCYSPKGGNYHSSLGTRCELSCDRGFRLI 98
Y E+ + Y P Y L + E T SP + + GT +C+ G+ L+
Sbjct: 2633 YFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELL 2692
Query: 99 GRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGVLLDSRCDYSCSSGYHLEG 157
G + C W+G+A C + C LP + + S YSC G+ L G
Sbjct: 2693 GNPVLICQEDGTWNGSAPSCISIECD-LPTAPENGFLRFTETSMGSAVQYSCKPGHILAG 2751
Query: 158 DRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTARVYWDPPLVKDSADGT 217
R+C+E+ +WSG P C I C M K + Y +
Sbjct: 2752 SDLRLCLENRKWSGASPRC-----EAISCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYV 2806
Query: 218 ITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTC 277
+ R + ++ E E + + V P Q
Sbjct: 2807 LNGTERRTCQDDKNWDEDEPI-----------------CIPVDCSSPPVSANGQ------ 2843
Query: 278 TSAGDNY--GATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPMKINVNVNSAAGLL 335
GD Y EY C+ G+ +G SRVC ++ WSG+ P C P++ A G+
Sbjct: 2844 -VRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVT 2902
Query: 336 D 336
+
Sbjct: 2903 E 2903
Score = 69.7 bits (169), Expect = 5e-12
Identities = 35/94 (37%), Positives = 48/94 (51%), Gaps = 2/94 (2%)
Query: 87 CELSCDRGFRLIGRRSVQCLPSRRWSGT-AYCRQMRCHALPFITSGTYTC-TNGVLLDSR 144
C + C GF L+G + CLP+ WSG+ +YCR C L G +C T +L +
Sbjct: 402 CGVRCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTT 461
Query: 145 CDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVD 178
C +C GY LEG C + +W G EP CV+
Sbjct: 462 CLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVE 495
Score = 69.7 bits (169), Expect = 5e-12
Identities = 72/298 (24%), Positives = 116/298 (38%), Gaps = 41/298 (13%)
Query: 76 GGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYT 134
G NY S G SC++GF + G + C + +WS C + C P + +G
Sbjct: 2159 GSNY--SFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLE 2216
Query: 135 CTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEP-VCVDID---PPKIRCPHSR 190
T G + +S Y C+ GY G +C + W P +CV +D PP I+ +
Sbjct: 2217 HTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFMK 2276
Query: 191 -EKMAEPEKLTARVYWDPPLVKDSA-----DGTITR------VTLRGPEPGSHFPEGEHV 238
E K+ LV DS+ G + + + PEP E + V
Sbjct: 2277 GENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEP--PLLENQLV 2334
Query: 239 IRYTAYDRAYNRASCK---FIVKVQVRRC----------PTLK------PPQHGY-LTCT 278
++ + SCK + V +C P K PP + +
Sbjct: 2335 LKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFGVPIP 2394
Query: 279 SAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPMKINVNVNSAAGLLD 336
S+ ++G+T +Y C GG+ +G + +CQ WS P C P++ G++D
Sbjct: 2395 SSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPVECPQPEEIPNGIID 2452
Score = 67.0 bits (162), Expect = 3e-11
Identities = 62/240 (25%), Positives = 91/240 (37%), Gaps = 30/240 (12%)
Query: 84 GTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGVLLD 142
G+ + SC GF L G + C P WS C + C I +G G+
Sbjct: 2401 GSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPVECPQPEEIPNGIID-VQGLAYL 2459
Query: 143 SRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTAR 202
S Y+C G+ L G+ + +C E+G W GG+P C I C +E + T
Sbjct: 2460 STALYTCKPGFELVGNTTTLCGENGHWLGGKPTC-----KAIECLKPKEILNGKFSYTDL 2514
Query: 203 VYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVR 262
Y + L GP + G D + SC I
Sbjct: 2515 HYGQTVTYSCNRG-----FRLEGPSALTCLETG---------DWDVDAPSCNAI------ 2554
Query: 263 RCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPM 322
C + +P ++G++ A +YGA Y C G+ G + C+ S WS S P C P+
Sbjct: 2555 HCDSPQPIENGFV--EGADYSYGAIIIYSCFPGFQVAGHAMQTCEES-GWSSSIPTCMPI 2611
Score = 65.5 bits (158), Expect = 1e-10
Identities = 60/252 (23%), Positives = 104/252 (41%), Gaps = 46/252 (18%)
Query: 84 GTRCELSCDRGFRLIGRRSVQCLPSRRWSGTAY---CRQMRCHALPFITSGTYTCTNGVL 140
G+ C GF L ++C+ +W+ + C +RC P I +G Y +
Sbjct: 2105 GSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNG-YASGSNYS 2163
Query: 141 LDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDI---DPPKIR---CPHSREKMA 194
+ YSC+ G++++G++ C G+WS P C + +PPK+ H+ ++
Sbjct: 2164 FGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIF 2223
Query: 195 EPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCK 254
E E R +P + G V A +R ++ S
Sbjct: 2224 ESE---VRYQCNP----------------------GYKSVGSPVFVCQA-NRHWHSESPL 2257
Query: 255 FIVKVQVRRCPTLKPPQHGYLTCTSAGDNY--GATCEYHCDGGYDRQGTPSRVCQSSRQW 312
V + + P P Q+G++ G+N+ G+ ++ C+ GY+ G S CQ S +W
Sbjct: 2258 MCVPLDCGKPP---PIQNGFM----KGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKW 2310
Query: 313 S-GSPPICAPMK 323
+ S P C P K
Sbjct: 2311 NKKSNPKCMPAK 2322
Score = 65.1 bits (157), Expect = 1e-10
Identities = 64/253 (25%), Positives = 94/253 (37%), Gaps = 44/253 (17%)
Query: 78 NYHSS-----LGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSG 131
N HSS +G SC G++L+G + CL S W+ YC+ + C P I
Sbjct: 1797 NGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSC-GKPAIPEN 1855
Query: 132 TYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSRE 191
S+ Y C+ GY L GD+ C+ + WS PVC +
Sbjct: 1856 GCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPV------------ 1903
Query: 192 KMAEPEKLTARVYWDPPL--VKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTA---YDR 246
K + PE + Y L + ++ T +L+GP +I TA +DR
Sbjct: 1904 KCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPS----------IIECTASGIWDR 1953
Query: 247 AYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVC 306
A +C + C +PP T + T Y C GY G + C
Sbjct: 1954 A--PPACHLVF------CG--EPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIEC 2003
Query: 307 QSSRQWSGSPPIC 319
+ +WS S C
Sbjct: 2004 LADGKWSRSDQQC 2016
Score = 63.9 bits (154), Expect = 3e-10
Identities = 68/265 (25%), Positives = 105/265 (39%), Gaps = 40/265 (15%)
Query: 84 GTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTN---GV 139
G SC+RGFRL G ++ CL + W A C + C + I +G + G
Sbjct: 2517 GQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYSYGA 2576
Query: 140 LLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDID---PPKI---RCPHSREKM 193
++ YSC G+ + G + C E G WS P C+ ID PP I C ++
Sbjct: 2577 II----IYSCFPGFQVAGHAMQTCEESG-WSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQ 2631
Query: 194 A--EPEKLTARVYW---DPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYT---AYD 245
E E V + PP + T S+F G ++ YT Y+
Sbjct: 2632 GYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSSNFLYGT-MVSYTCNPGYE 2690
Query: 246 RAYN-----------RASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDG 294
N S + ++ C P++G+L T + G+ +Y C
Sbjct: 2691 LLGNPVLICQEDGTWNGSAPSCISIE---CDLPTAPENGFLRFTET--SMGSAVQYSCKP 2745
Query: 295 GYDRQGTPSRVCQSSRQWSGSPPIC 319
G+ G+ R+C +R+WSG+ P C
Sbjct: 2746 GHILAGSDLRLCLENRKWSGASPRC 2770
Score = 63.5 bits (153), Expect = 4e-10
Identities = 63/233 (27%), Positives = 85/233 (36%), Gaps = 35/233 (15%)
Query: 91 CDRGFRLIGRRSVQCLPSRRWSG-TAYCRQMRCHALPFITSGTYTCTNGVLLDSRCDYSC 149
C+ G+ L G R C +R+WSG A C++ RC +G N YSC
Sbjct: 3267 CEPGYELEGNRERVCQENRQWSGGVAICKETRCETPLEFLNGKADIENRTT-GPNVVYSC 3325
Query: 150 SSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTARVYWDPPL 209
+ GY LEG C E+G WS P+C P ++E E Y D +
Sbjct: 3326 NRGYSLEGPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENALLSEKE-----FYVDQNV 3380
Query: 210 VKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLK- 268
+G + L+G H I D + + S K C +
Sbjct: 3381 SIKCREGFL----LQG-----------HGIITCNPDETWTQTSAK---------CEKISC 3416
Query: 269 -PPQH-GYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
PP H YG Y C GY +G VC + W+ SPPIC
Sbjct: 3417 GPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWT-SPPIC 3468
Score = 62.8 bits (151), Expect = 6e-10
Identities = 64/249 (25%), Positives = 96/249 (38%), Gaps = 33/249 (13%)
Query: 77 GNYHSSLGTRCELSCDRGFRLIG-RRSVQCLPSRRWS---GTAYCR-----QMRC----- 122
G + GT C +SC +GF L G + ++C S +W+ A C+ Q+ C
Sbjct: 515 GKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAPQINCPKDIE 574
Query: 123 -HALPFITSGTYTC-------TNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEP 174
L S T +G + + + Y I SG +
Sbjct: 575 AKTLEQQDSANVTWQIPTAKDNSGEKVSVHVHPAFTPPYLFPIGDVAIVYTATDLSGNQA 634
Query: 175 VCV------DIDPPKIRCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEP 228
C+ D +PP I S + EK+ A WD P D++ + V R
Sbjct: 635 SCIFHIKVIDAEPPVIDWCRSPPPVQVSEKVHA-ASWDEPQFSDNSGAEL--VITRSHTQ 691
Query: 229 GSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATC 288
G FP+GE +++YTA D + N +C + ++ C P +G CT DN G C
Sbjct: 692 GDLFPQGETIVQYTATDPSGNNRTCDIHIVIKGSPCEIPFTPVNGDFICTP--DNTGVNC 749
Query: 289 EYHCDGGYD 297
C GYD
Sbjct: 750 TLTCLEGYD 758
Score = 60.5 bits (145), Expect = 3e-09
Identities = 24/60 (40%), Positives = 35/60 (58%)
Query: 260 QVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
+VR CP L+ P+HG+++C++ Y TC CD GY +G+ CQ + QW G P C
Sbjct: 434 RVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRC 493
Score = 60.5 bits (145), Expect = 3e-09
Identities = 72/306 (23%), Positives = 108/306 (35%), Gaps = 59/306 (19%)
Query: 63 NIQDGEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWS-GTAYCRQMR 121
NI +G+ Y G Y S+ SCD G+ L G ++C S W C +
Sbjct: 1910 NINNGK---YILSGLTYLST----ASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVF 1962
Query: 122 CHALPFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVC--VDI 179
C P I T N ++ Y+C GY L G + C+ DG+WS + C V
Sbjct: 1963 CGEPPAIKDAVITGNNFTFRNT-VTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSC 2021
Query: 180 DPPKIRCPHSRE------------------KMAEPEKL--TARVYWDPPLVKDSADGTIT 219
D P I S E +A+ +L A+ W PP +D I
Sbjct: 2022 DEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQD-MPRCIA 2080
Query: 220 RVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVR----------------- 262
+ P E ++ A + F++ +
Sbjct: 2081 HFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQ 2140
Query: 263 ----RCPTLKPPQHGYLTCTSAGDNY--GATCEYHCDGGYDRQGTPSRVCQSSRQWSGSP 316
RC +GY ++G NY GA Y C+ G+ +G C+++ QWS
Sbjct: 2141 CIPVRCGEPPSIMNGY----ASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPI 2196
Query: 317 PICAPM 322
P C P+
Sbjct: 2197 PTCHPV 2202
Score = 55.8 bits (133), Expect = 8e-08
Identities = 66/294 (22%), Positives = 93/294 (31%), Gaps = 88/294 (29%)
Query: 88 ELSCDRGFRLIGRRSVQCLPSRRWSG-TAYCRQMRCHALPFITSG-------------TY 133
E +C+ GF L G RS CL + WSG T C +RC P + +G T+
Sbjct: 2856 EYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVTF 2915
Query: 134 TCTNGVLL----------DSRCD----------------------------------YSC 149
C G +L D D Y C
Sbjct: 2916 HCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHGFPNGFSFIHGGHIQYQC 2975
Query: 150 SSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTARVYWDPPL 209
GY L G+ SR C+ +G WSG P C+ P + P
Sbjct: 2976 FPGYKLHGNSSRRCLSNGSWSGSSPSCL---PCRCSTPVIEYGTVNGTDFDCGKAARIQC 3032
Query: 210 VKDSADGTITRVTLRGP-EPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLK 268
K ++ +T + S FP EH C +L
Sbjct: 3033 FKGFKLLGLSEITCEADGQWSSGFPHCEHT------------------------SCGSLP 3068
Query: 269 PPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPM 322
+ +++ TS+ T Y C GY QG+ +C WS P+C P+
Sbjct: 3069 MIPNAFISETSSWKENVIT--YSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPL 3120
Score = 50.8 bits (120), Expect = 3e-06
Identities = 20/56 (35%), Positives = 30/56 (53%)
Query: 264 CPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
CP LKPP++GY + +++ A C C G+D G+ +C + WSGS C
Sbjct: 378 CPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGSESYC 433
Score = 50.4 bits (119), Expect = 3e-06
Identities = 30/93 (32%), Positives = 43/93 (46%), Gaps = 11/93 (11%)
Query: 89 LSCDRGFRLIGRRSVQCLPSRRWSGT-AYCRQMRC----HALPFITSGTYTCTNGVLLDS 143
+ C GF L G + C P W+ T A C ++ C H I G + ++
Sbjct: 3382 IKCREGFLLQGHGIITCNPDETWTQTSAKCEKISCGPPAHVENAIARGVHYQYGDMIT-- 3439
Query: 144 RCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVC 176
YSC SGY LEG +C+E+G W+ P+C
Sbjct: 3440 ---YSCYSGYMLEGFLRSVCLENGTWT-SPPIC 3468
Score = 49.7 bits (117), Expect = 6e-06
Identities = 33/96 (34%), Positives = 43/96 (44%), Gaps = 7/96 (7%)
Query: 84 GTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGVLLD 142
G + C G++L G S +CL + WSG++ C RC + P I GT NG D
Sbjct: 2968 GGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRC-STPVIEYGT---VNGTDFD 3023
Query: 143 --SRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVC 176
C G+ L G C DG+WS G P C
Sbjct: 3024 CGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHC 3059
Score = 49.3 bits (116), Expect = 7e-06
Identities = 27/103 (26%), Positives = 41/103 (39%), Gaps = 14/103 (13%)
Query: 82 SLGTRCELSCDRGFRLIGRRSVQCLPSRRWS--------GTAYCRQMRCHALPFITSGTY 133
S+ + +SC G+ G C W C + F+ Y
Sbjct: 3198 SVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKY 3257
Query: 134 TCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVC 176
T + ++ Y C GY LEG+R R+C E+ +WSGG +C
Sbjct: 3258 TFESTII------YQCEPGYELEGNRERVCQENRQWSGGVAIC 3294
Score = 48.1 bits (113), Expect = 2e-05
Identities = 53/260 (20%), Positives = 93/260 (35%), Gaps = 57/260 (21%)
Query: 75 KGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWS--GTAYCRQMRCHALPFITSGT 132
KG N+ +G++ + C+ G+ L+G S C S +W+ C +C P + +
Sbjct: 2276 KGENFE--VGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLENQL 2333
Query: 133 Y----TCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPH 188
T GV+ +SC G+ L+G C+ +W+ PVC +
Sbjct: 2334 VLKELTTEVGVVT-----FSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIV--------- 2379
Query: 189 SREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAY 248
+ P PPL+ P P S G ++Y+ +
Sbjct: 2380 ----LCTP----------PPLISFGV-----------PIPSSALHFGS-TVKYSCVGGFF 2413
Query: 249 NRASCKFIVKVQ------VRRCPTLKPPQHGYL---TCTSAGDNYGATCEYHCDGGYDRQ 299
R + + + + C ++ PQ + G Y +T Y C G++
Sbjct: 2414 LRGNSTTLCQPDGTWSSPLPECVPVECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELV 2473
Query: 300 GTPSRVCQSSRQWSGSPPIC 319
G + +C + W G P C
Sbjct: 2474 GNTTTLCGENGHWLGGKPTC 2493
Score = 43.1 bits (100), Expect = 5e-04
Identities = 29/91 (31%), Positives = 41/91 (45%), Gaps = 13/91 (14%)
Query: 105 CLPSRRWSGTAYCRQMRCHALPFITSGTY---TCTNGVLLDSRCDYSCSSGYHLEGDRSR 161
C R SG C + C AL +G + TC N ++ C C G+ L G
Sbjct: 362 CREGYRASGQT-CELVHCPALKPPENGYFIQNTCNNH--FNAACGVRCHPGFDLVGSSII 418
Query: 162 ICMEDGRWSGGEPVCVDIDPPKIR-CPHSRE 191
+C+ +G WSG E C ++R CPH R+
Sbjct: 419 LCLPNGLWSGSESYC------RVRTCPHLRQ 443
Score = 39.7 bits (91), Expect = 0.006
Identities = 64/285 (22%), Positives = 93/285 (32%), Gaps = 72/285 (25%)
Query: 90 SCDRGFRLIGRRSVQCLPSRRWSGT-AYCRQMRCHALPFITSGTYTCTNGVLLDSRCDYS 148
SC G+ + G + C WS C + C + P + + T +S
Sbjct: 3089 SCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPSVANAVAT-GEAHTYESEVKLR 3147
Query: 149 CSSGYHLEGDRSRI-CMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLT------- 200
C GY ++ D C +DGRW P +I C S +K PE +T
Sbjct: 3148 CLEGYTMDTDTDTFTCQKDGRWF----------PERISC--SPKKCPLPENITHILVHGD 3195
Query: 201 ------------ARVY---------------WDPPLVKDSADGTITRVTLRGPEPGSH-F 232
A Y W+PP +D + + V+ PE H F
Sbjct: 3196 DFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPF----SDESCSPVSCGKPESPEHGF 3251
Query: 233 PEG-----EHVIRYTA---YDRAYNRAS-CKF-------IVKVQVRRCPTLKPPQHGYLT 276
G E I Y Y+ NR C+ + + RC T +G
Sbjct: 3252 VVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKETRCETPLEFLNGKAD 3311
Query: 277 CTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAP 321
+ G Y C+ GY +G C + WS P+C P
Sbjct: 3312 IENR--TTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKP 3354
Score = 37.0 bits (84), Expect = 0.038
Identities = 28/124 (22%), Positives = 40/124 (32%), Gaps = 9/124 (7%)
Query: 68 EATCYSP------KGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWS-GTAYCRQM 120
E C +P K + + G SC+RG+ L G C + WS C+
Sbjct: 3296 ETRCETPLEFLNGKADIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPN 3355
Query: 121 RCHALPFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVC--VD 178
C I +D C G+ L+G C D W+ C +
Sbjct: 3356 PCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAKCEKIS 3415
Query: 179 IDPP 182
PP
Sbjct: 3416 CGPP 3419
Score = 29.6 bits (65), Expect = 6.1
Identities = 24/98 (24%), Positives = 34/98 (34%), Gaps = 23/98 (23%)
Query: 80 HSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTAYCRQMRCHALPFITSGTYTCTNGV 139
H G SC G+ L G CL + W+ CR + C + C NG
Sbjct: 3431 HYQYGDMITYSCYSGYMLEGFLRSVCLENGTWTSPPICRAV-CR---------FPCQNGG 3480
Query: 140 LLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCV 177
+ SC G+ R+C EP+C+
Sbjct: 3481 ICQRPNACSCPEGW-----MGRLC--------EEPICI 3505
>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
Length = 3565
Score = 77.0 bits (188), Expect = 3e-14
Identities = 71/250 (28%), Positives = 109/250 (43%), Gaps = 36/250 (14%)
Query: 82 SLGTRCELSCDRGFRLIGRRSVQC----LPSRRWSG-TAYCRQMRCHALPFITSGTYTCT 136
++G++ C G+R++G + C L +W T C+ + C +G++T
Sbjct: 2451 AVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFT-G 2509
Query: 137 NGVLLDSRCDYSCSSGYHLEGDR--SRICMEDGRWS--GGEPVCVDIDPPKIRCPHSREK 192
N LDS+ Y C G+ LE + + +C EDG WS G P C + P I
Sbjct: 2510 NEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEA------ 2563
Query: 193 MAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTA---YDRAYN 249
+L+ V W LV S + +V L PG ++ EG ++R A ++
Sbjct: 2564 -----QLSEHVIWR--LVSGSLNEYGAQVLL-SCSPG-YYLEGWRLLRCQANGTWNIGDE 2614
Query: 250 RASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSS 309
R SC+ I C +L P +G T YGAT + C+ GY G+ R C ++
Sbjct: 2615 RPSCRVI------SCGSLSFPPNGNKIGTLTV--YGATAIFTCNTGYTLVGSHVRECLAN 2666
Query: 310 RQWSGSPPIC 319
WSGS C
Sbjct: 2667 GLWSGSETRC 2676
Score = 73.2 bits (178), Expect = 5e-13
Identities = 79/311 (25%), Positives = 113/311 (36%), Gaps = 57/311 (18%)
Query: 61 TLNIQDGEATCYS--------PKGGNYHSSL---GTRCELSCDRGFRLIGRRSVQCLPSR 109
T NI D +C P GN +L G +C+ G+ L+G +CL +
Sbjct: 2608 TWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANG 2667
Query: 110 RWSGT-AYCRQMRCHALPFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGR 168
WSG+ C C + I +G + +G Y C+ G+ L G RIC++D +
Sbjct: 2668 LWSGSETRCLAGHCGSPDPIVNG-HISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHK 2726
Query: 169 WSGGEPVCVDI------DPPKIRCPHSREKMAEPEKLTARV----------------YWD 206
WSG PVCV I +P S + + T W
Sbjct: 2727 WSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWS 2786
Query: 207 PPL-----VKDSADGTITRVTLRGPE--PGS---------HFPEGEHVIRYTAYDRAYNR 250
PL V S G + G + P S H +G +++ +A N
Sbjct: 2787 SPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANG 2846
Query: 251 ASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGD--NYGATCEYHCDGGYDRQGTPSRVCQS 308
+ + K C P + LT G+ YGA Y C G G +RVCQ
Sbjct: 2847 LWDRSLPKCLAISCGHPGVPANAVLT----GELFTYGAVVHYSCRGSESLIGNDTRVCQE 2902
Query: 309 SRQWSGSPPIC 319
WSG+ P C
Sbjct: 2903 DSHWSGALPHC 2913
Score = 68.6 bits (166), Expect = 1e-11
Identities = 57/236 (24%), Positives = 89/236 (37%), Gaps = 30/236 (12%)
Query: 90 SCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGVLLDSRCDYS 148
SC+ G +L G CL + WSG C + C T+G ++G+L S Y+
Sbjct: 2946 SCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYA 3005
Query: 149 CSSGYHLEGDRSRICMEDGRWSGGEPVC--VDIDPPKIRCPHSREKMAEPEKLTARVYWD 206
C GY G +R C +G W+G P C + P + T +
Sbjct: 3006 CWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCN 3065
Query: 207 PPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPT 266
P V ++ +T T+R + G P ++ CK ++ CP
Sbjct: 3066 PGYVMEA----VTSATIRCTKDGRWNP---------------SKPVCKAVL------CPQ 3100
Query: 267 LKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPM 322
P Q+G T + +G++ Y C GY + C+ W G P C P+
Sbjct: 3101 PPPVQNG--TVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPV 3154
Score = 53.9 bits (128), Expect = 3e-07
Identities = 53/238 (22%), Positives = 88/238 (36%), Gaps = 35/238 (14%)
Query: 91 CDRGFRL--IGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGVLLDSRCDY 147
C+ G+ + + +++C RW+ + C+ + C P + +GT ++ S Y
Sbjct: 3064 CNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSD-FRWGSSISY 3122
Query: 148 SCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTARVYWD- 206
SC GY L C G W G P C+ + P + + V++
Sbjct: 3123 SCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSFTYKSEVFFQC 3182
Query: 207 -PPLVKDSADGTITRV--TLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRR 263
P + + + + T G +P T D A+N
Sbjct: 3183 KSPFILVGSSRRVCQADGTWSGIQP-------------TCIDPAHNT------------- 3216
Query: 264 CPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAP 321
CP P G + +S G G+T + C GY QG+ +R C ++ WSG C P
Sbjct: 3217 CPDPGTPHFG-IQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIP 3273
Score = 53.1 bits (126), Expect = 5e-07
Identities = 57/242 (23%), Positives = 81/242 (33%), Gaps = 33/242 (13%)
Query: 84 GTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGVLLD 142
G+ SC G++L + C W G C + C P I +
Sbjct: 3117 GSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGD-PGIPAEGRLSGKSFTYK 3175
Query: 143 SRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTAR 202
S + C S + L G R+C DG WSG +P C IDP CP
Sbjct: 3176 SEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTC--IDPAHNTCP--------------- 3218
Query: 203 VYWDPPLVKDSADGTITRVTLRGPEPGS----HFPEGEHVIRYTAYDRAYNRASCKFIVK 258
DP + RG E GS +G H+ T N +
Sbjct: 3219 ---DPGTPHFGIQN-----SSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTE 3270
Query: 259 VQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYD-RQGTPSRVCQSSRQWSGSPP 317
C + P H + +G T Y C G+ G+ R C++ +W+G P
Sbjct: 3271 CIPHACRQPETPAHADVRAIDL-PTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSP 3329
Query: 318 IC 319
+C
Sbjct: 3330 VC 3331
Score = 51.2 bits (121), Expect = 2e-06
Identities = 52/231 (22%), Positives = 84/231 (36%), Gaps = 27/231 (11%)
Query: 91 CDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGVLLDSRCDYSC 149
C +GF L+G ++ C+ + W + C + C P + + + YSC
Sbjct: 2828 CKKGFYLLGSSALTCMANGLWDRSLPKCLAISC-GHPGVPANAVLTGELFTYGAVVHYSC 2886
Query: 150 SSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTARVYWDPPL 209
L G+ +R+C ED WSG P C +P P + P
Sbjct: 2887 RGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGT-----------------PAH 2929
Query: 210 VKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKV-QVRRCPTLK 268
D T+ LR E H +R + S + V + C
Sbjct: 2930 GSRLGDDFKTKSLLR------FSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPG 2983
Query: 269 PPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
P +G + +S G + ++ Y C GY G +R C ++ W+G+ P C
Sbjct: 2984 TPTNGMIV-SSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDC 3033
Score = 40.8 bits (94), Expect = 0.003
Identities = 30/100 (30%), Positives = 38/100 (38%), Gaps = 11/100 (11%)
Query: 84 GTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGVLLD 142
G SC LIG + C WSG +C P T +G L
Sbjct: 2879 GAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNN----PGFCGDPGTPAHGSRLG 2934
Query: 143 ------SRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVC 176
S +SC G+ L G R C+ +G WSG +PVC
Sbjct: 2935 DDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVC 2974
Score = 40.4 bits (93), Expect = 0.003
Identities = 49/212 (23%), Positives = 80/212 (37%), Gaps = 47/212 (22%)
Query: 147 YSCSSGYHLEGDRSRICMEDGRWSGGEPVCV-------DIDPPKIRCPHSREK------- 192
+ C + + L G+R C ++ +WSG +P CV I P+ E+
Sbjct: 552 FECPAAFELVGERVITCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNC 611
Query: 193 ----MAEPEKLTARVY--------WDPPLVKDSADGTITRV-TLRGPEPGSHFPEGEHVI 239
++EP ++ +D VKD IT + T G E S H++
Sbjct: 612 VWLIISEPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIV 671
Query: 240 R------YTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNY--GATCEYH 291
R ++ R +N F C P +G GD + G++ +H
Sbjct: 672 RLEFQSDHSTTGRGFNITYTTF----GQNECHDPGIPING----RRFGDRFLLGSSVSFH 723
Query: 292 CDGGYDR-QGTPSRVC---QSSRQWSGSPPIC 319
CD G+ + QG+ S C + WS + P C
Sbjct: 724 CDDGFVKTQGSESITCILQDGNVVWSSTVPRC 755
Score = 39.7 bits (91), Expect = 0.006
Identities = 27/101 (26%), Positives = 41/101 (40%), Gaps = 12/101 (11%)
Query: 83 LGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTAY------CRQMRCHALPFITSGTYTCT 136
+G+ C +G+ + G + CL + WSG CRQ A + +
Sbjct: 3236 VGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTF 3295
Query: 137 NGVLLDSRCDYSCSSGYHLEG-DRSRICMEDGRWSGGEPVC 176
L+ Y+C G+ L G R C D +W+G PVC
Sbjct: 3296 GYTLV-----YTCHPGFFLAGGSEHRTCKADMKWTGKSPVC 3331
Score = 36.6 bits (83), Expect = 0.050
Identities = 51/219 (23%), Positives = 73/219 (33%), Gaps = 41/219 (18%)
Query: 138 GVLLDSRCDYSCSSGYHLEGDRSRICMEDGR--WSGGEPVCVD-------------IDPP 182
G D+ YSC+ GY + G + C+ R W P C+ I P
Sbjct: 1234 GHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAECGGQIHAATSGRILSP 1293
Query: 183 KIRCPHSREKM------AEPEKLTAR--VYWDPPLVKDSA---DGTITRVTLRGPEPGSH 231
P+ A+P K + + +D + D DG + L GS
Sbjct: 1294 GYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDILKVWDGPVDSDILLKEWSGSA 1353
Query: 232 FPEGEHVIRYTA---YDRAYNRASCKFIVKVQVRRCPTLKPP---QHGYLTCTSAGDNY- 284
PE H + +D + + F ++ T P Q+G T GD+
Sbjct: 1354 LPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCNDPGMPQNG----TRYGDSRE 1409
Query: 285 -GATCEYHCDGGYDRQGTPSRVCQSSRQ---WSGSPPIC 319
G T + CD GY QG C W PP C
Sbjct: 1410 AGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC 1448
Score = 35.4 bits (80), Expect = 0.11
Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 11/79 (13%)
Query: 264 CPTLKPPQHGYLTCTSAGDNY---GATCEYHCDGGYDRQGTPSRVCQSSRQ----WSGSP 316
CP P++G AG ++ GA ++ C+ Y QG+ S CQ + WS
Sbjct: 349 CPDPGIPENG----RRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHR 404
Query: 317 PICAPMKINVNVNSAAGLL 335
PIC N+ +G++
Sbjct: 405 PICRARTCGSNLRGPSGVI 423
Score = 33.5 bits (75), Expect = 0.42
Identities = 14/52 (26%), Positives = 25/52 (48%), Gaps = 1/52 (1%)
Query: 284 YGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPMKINVNVNSAAGLL 335
+G T + C ++ G CQ + QWSG+ P C N +++G++
Sbjct: 546 HGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCV-FSCFFNFTASSGII 596
Score = 32.3 bits (72), Expect = 0.94
Identities = 55/256 (21%), Positives = 96/256 (37%), Gaps = 58/256 (22%)
Query: 83 LGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTAYCRQMRCHALPFITSGTYTCTNGVLLD 142
LG+ CD G++++ S+ C+ + C+A G YT + GV+L
Sbjct: 1583 LGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNAP---CGGQYTGSEGVVLS 1639
Query: 143 SRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTAR 202
++ ++G +IC+ I PK E
Sbjct: 1640 PNYPHNYTAG--------QICL------------YSITVPK-----------EFVVFGQF 1668
Query: 203 VYWDPPL--VKDSADGTITRVTLRGPEPGSHFPE-------GEHVIRYTAYDRAYNRASC 253
Y+ L + + DGT + L GSH E + ++R++A A R
Sbjct: 1669 AYFQTALNDLAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGF- 1727
Query: 254 KFIVKVQVR----RCPTLKPPQHGYLTCTSAGDNY--GATCEYHCDGGYDRQGTPSRVCQ 307
F+ + R +C ++ P++G G + G+ + C+ GY QG+ + CQ
Sbjct: 1728 HFVYQAVPRTSDTQCSSVPEPRYG----RRIGSEFSAGSIVRFECNPGYLLQGSTALHCQ 1783
Query: 308 S----SRQWSGSPPIC 319
S QW+ + P C
Sbjct: 1784 SVPNALAQWNDTIPSC 1799
Score = 30.8 bits (68), Expect = 2.7
Identities = 52/222 (23%), Positives = 82/222 (36%), Gaps = 51/222 (22%)
Query: 140 LLDSRCDYSCSSGY-HLEGDRSRIC-MEDGR--WSGGEPVCVD------------IDPP- 182
LL S + C G+ +G S C ++DG WS P C I PP
Sbjct: 715 LLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPG 774
Query: 183 -------KIRCPHSREKMAEP--------EKLTARVYWDPPLVKDSADGTITRVTLRGPE 227
+ C E A+P ++ V +D V+D G + L G
Sbjct: 775 WPGYYKDSLHCEWIIE--AKPGHSIKITFDRFQTEVNYDTLEVRD---GPASSSPLIGEY 829
Query: 228 PGSHFPE---GEHVIRYTAYDRAYNRASCKFIV---KVQVRRCPTLKP--PQHGYLTCTS 279
G+ P+ Y + +R+S F++ V + L P P +G+
Sbjct: 830 HGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDPGIPVNGH----R 885
Query: 280 AGDNYG--ATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
G ++G +T + CD GY VC+ + QW+ + P C
Sbjct: 886 HGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSC 927
Score = 30.4 bits (67), Expect = 3.6
Identities = 15/33 (45%), Positives = 17/33 (51%), Gaps = 2/33 (6%)
Query: 147 YSCSSGYHLEGDRSRICMEDGR--WSGGEPVCV 177
+SC GY LEG C+ GR WS P CV
Sbjct: 1070 FSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCV 1102
>gi|54792123 complement component (3d/Epstein Barr virus) receptor 2
isoform 1 [Homo sapiens]
Length = 1092
Score = 74.3 bits (181), Expect = 2e-13
Identities = 78/328 (23%), Positives = 113/328 (34%), Gaps = 61/328 (18%)
Query: 68 EATCYSPKGGNYHSSLGTRCEL---SCDRGFRLIGRRSVQCLPSRR---WSGTAYCRQMR 121
E TC + G+R EL SC G++L G C + + C+ +
Sbjct: 718 EETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIH 777
Query: 122 CHALPFITSGTYT--CTNGVLLDSRCDYSCSSGYHLEGDRSRICMED----GRWSGGEPV 175
CH P I +G +T L + Y C G++L G++ C D G WSG P
Sbjct: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
Query: 176 CVDIDPPKIRCPHSREKMAEPEKLTARVYWDPPLVK-DSADG------------------ 216
C+ PP RCP+ K T Y +V D G
Sbjct: 838 CLR-SPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWV 896
Query: 217 ----TITRVTLRGPEPGSHFPEGEH----VIRYT-AYDRAYNRASCKFIVKVQVRRCP-- 265
T + G P P G H + R++ Y+ +V + C
Sbjct: 897 PGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHE 956
Query: 266 ---TLKPPQHGYLTCTSAGD--------------NYGATCEYHCDGGYDRQGTPSRVCQS 308
+ P + C+S D YGA C+ GY +G+P CQS
Sbjct: 957 GTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQS 1016
Query: 309 SRQWSGSPPICAPMKI-NVNVNSAAGLL 335
QW+ +C + V AAGL+
Sbjct: 1017 DHQWNPPLAVCRSRSLAPVLCGIAAGLI 1044
Score = 58.9 bits (141), Expect = 9e-09
Identities = 60/238 (25%), Positives = 82/238 (34%), Gaps = 38/238 (15%)
Query: 91 CDRGFRLIGRRSVQCLPSRRWSGTAYCRQMRCHALPFITSGTYTCTNGVLLDS--RCDYS 148
C GF L G ++C W + C + P + G +T N V S DY+
Sbjct: 630 CYSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYT 689
Query: 149 CSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTARVYWDPP 208
C GY L G++S CM G WS P C + C H R+ + E
Sbjct: 690 CDPGYLLVGNKSIHCMPSGNWSPSAPRCEE------TCQHVRQSLQE------------- 730
Query: 209 LVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRC---P 265
L S + G + H Y A N K I +V C P
Sbjct: 731 LPAGSRVELVNTSCQDGYQLTGH--------AYQMCQDAENGIWFKKIPLCKVIHCHPPP 782
Query: 266 TLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQ----WSGSPPIC 319
+ +H + + YG Y CD G+ G C+S + WSG P C
Sbjct: 783 VIVNGKHTGMMAENF--LYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQC 838
Score = 58.2 bits (139), Expect = 2e-08
Identities = 64/282 (22%), Positives = 100/282 (35%), Gaps = 54/282 (19%)
Query: 90 SCDRGFRLIGRRSVQCLPSRRWSGTAYCRQMRCHALPFITSGTYTCTNGVLLD--SRCDY 147
+C GF L G + ++C W +A + C A P I +G + V D + Y
Sbjct: 378 ACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKY 437
Query: 148 SCSSGYHLEGDRSRICMEDGRWSGGEPVC------------VDIDPPKIRCPHSREKMAE 195
SC+ GY L G+ S C +G W+ P C + + P E
Sbjct: 438 SCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGE 497
Query: 196 PEKLTARVYWD---------------------PPLVKDSA-----------DGTITRVTL 223
KL+ VY + PP++ + A T+T
Sbjct: 498 GYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCN 557
Query: 224 RGPEPGSHFP-EGEHVIRYTAYDRAYNRAS-----CKFIVKVQVRRCPTLKPPQHGYLTC 277
GPE G F GE IR T+ D+ S CK + + +C + ++
Sbjct: 558 PGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCK--LSLLAVQCSHVHIANGYKISG 615
Query: 278 TSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
A Y T + C G+ +G+ C++ W P+C
Sbjct: 616 KEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVC 657
Score = 57.4 bits (137), Expect = 3e-08
Identities = 62/258 (24%), Positives = 96/258 (37%), Gaps = 48/258 (18%)
Query: 84 GTRCELSCDRGFRLIGRRSVQCLPSRRWSGTAYCR-----QMRCHALPFITSGTYTCTN- 137
G +C F + G +SV C + W T + C ALP I +G +T N
Sbjct: 111 GDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENV 170
Query: 138 -GVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKI-RCPHSREKMAE 195
+ YSC SGY L G++ C+ G+WS P C + + R P+ + K
Sbjct: 171 GSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVK--- 227
Query: 196 PEKLTARVYWDPPLVKDSADGTI---TRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRAS 252
+PP+++ L+GP P S + +T
Sbjct: 228 ----------EPPILRVGVTANFFCDEGYRLQGP-PSSRCVIAGQGVAWT------KMPV 270
Query: 253 CKFIVKVQVRRCPTLKPPQHG-YLTCTSAGDNYGATCEYHCDGGYDRQ------GTPSRV 305
C+ I CP+ P +G ++ + A +YG+ Y CD + G +
Sbjct: 271 CEEIF------CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLR 324
Query: 306 C----QSSRQWSGSPPIC 319
C Q + WSG P C
Sbjct: 325 CTVDSQKTGTWSGPAPRC 342
Score = 53.1 bits (126), Expect = 5e-07
Identities = 61/279 (21%), Positives = 103/279 (36%), Gaps = 61/279 (21%)
Query: 68 EATCYSPKGGNY--HSS-------LGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA--- 115
E C SP G ++ H+ G + +CD G+ L+G +S+ C+PS WS +A
Sbjct: 658 EKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRC 717
Query: 116 --YCRQMRCHALPFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICM--EDGRWSG 171
C+ +R +L + +G+ + SC GY L G ++C E+G W
Sbjct: 718 EETCQHVR-QSLQELPAGSRV--------ELVNTSCQDGYQLTGHAYQMCQDAENGIWFK 768
Query: 172 GEPVC--VDIDPPKIRCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPG 229
P+C + PP P +V G + L G E
Sbjct: 769 KIPLCKVIHCHPP------------------------PVIVNGKHTGMMAENFLYGNEVS 804
Query: 230 SHFPEGEHVIRYTAYD--------RAYNRASCKFIVKVQVRRCPTLKPPQHGY-LTCTSA 280
+G +++ +++ S + + V RCP +HGY L T +
Sbjct: 805 YECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPN-PEVKHGYKLNKTHS 863
Query: 281 GDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
++ C+ G+ G+ C + W P C
Sbjct: 864 AYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTC 902
Score = 45.8 bits (107), Expect = 8e-05
Identities = 32/121 (26%), Positives = 54/121 (44%), Gaps = 16/121 (13%)
Query: 83 LGTRCELSCDRGFRLIGRRSVQCLPSRR---WSGTAYCRQMRCHALPFITSGTY------ 133
+G CD G+RL G S +C+ + + W+ C ++ C + P I +G +
Sbjct: 234 VGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLA 293
Query: 134 TCTNGVLLDSRCDYSCSSG--YHLEGDRSRICMED----GRWSGGEPVCVDIDPPKIRCP 187
+ G ++ CD G + L G+ + C D G WSG P C ++ ++CP
Sbjct: 294 NVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRC-ELSTSAVQCP 352
Query: 188 H 188
H
Sbjct: 353 H 353
Score = 43.1 bits (100), Expect = 5e-04
Identities = 59/262 (22%), Positives = 91/262 (34%), Gaps = 56/262 (21%)
Query: 82 SLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTAYCRQMRCHALPFITS-------GTYT 134
++GT SC FRLIG +S+ C+ + GT +C +S G Y
Sbjct: 42 AVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKYSSCPEPIVPGGYK 101
Query: 135 CTNGVLL--DSRCDYSCSSGYHLEGDRSRICMEDGRWSGGE-PVCVDIDPPKIRCP---- 187
++C + + + G++S C + W P CV + P + CP
Sbjct: 102 IRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVFP--LECPALPM 159
Query: 188 -HSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVI------R 240
H+ +E V A G + + GE +I +
Sbjct: 160 IHNGHHTSEN-------------VGSIAPGLSVTYSCE----SGYLLVGEKIINCLSSGK 202
Query: 241 YTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQG 300
++A A CK + R P K + L G T + CD GY QG
Sbjct: 203 WSAVPPTCEEARCK-----SLGRFPNGKVKEPPIL-------RVGVTANFFCDEGYRLQG 250
Query: 301 TPSRVCQSSRQ---WSGSPPIC 319
PS C + Q W+ P+C
Sbjct: 251 PPSSRCVIAGQGVAWT-KMPVC 271
Score = 40.8 bits (94), Expect = 0.003
Identities = 71/305 (23%), Positives = 107/305 (35%), Gaps = 70/305 (22%)
Query: 78 NYHSSLGTRCELSCDRG--FRLIGRRSVQCLPSRRWSGTAYCRQMRCHALPFITSGTYTC 135
+Y S + C+ + G F LIG +++C + +GT RC +++ C
Sbjct: 296 SYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCE----LSTSAVQC 351
Query: 136 TNGVLLDSRCD--------------YSCSSGYHLEGDRSRICMEDGRWSGGEPVC----- 176
+ +L R ++C G+ L+G + C G W PVC
Sbjct: 352 PHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQ 411
Query: 177 ---------------VDIDPP---KIRCPHSREKMAEPE-KLTARVYWDPPL--VKDSAD 215
V DP K C + E + T+ W PP+ K +A
Sbjct: 412 APPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAAC 471
Query: 216 GTITRVTLRGPE-----PGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCP--TLK 268
R L P+ P + GE Y Y +++R C T
Sbjct: 472 EATGRQLLTKPQHQFVRPDVNSSCGE---GYKLSGSVYQECQGTIPWFMEIRLCKEITCP 528
Query: 269 PP---QHGYLTCTSAGD-NYGATCEYHCDGGYDRQ------GTPSRVCQSSRQ----WSG 314
PP +G T +S D YG T Y C+ G +R G + C S+ Q WSG
Sbjct: 529 PPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSG 588
Query: 315 SPPIC 319
P+C
Sbjct: 589 PAPLC 593
>gi|38045915 pregnancy-associated plasma protein A preproprotein [Homo
sapiens]
Length = 1627
Score = 73.9 bits (180), Expect = 3e-13
Identities = 68/299 (22%), Positives = 114/299 (38%), Gaps = 72/299 (24%)
Query: 59 CYTLNIQDGEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSR--------- 109
C L +++ C S YH G +C +SC G+ L RR + + S+
Sbjct: 1215 CPELAVENASLNCSS--SDRYH---GAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTC 1269
Query: 110 ---RWSGTAYCRQMRCHALPF---ITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRI- 162
+W+ C + C ++P + + +++C G S+C + C L+G+ S +
Sbjct: 1270 TEGKWNKQVACEPVDC-SIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLT 1328
Query: 163 CMEDGRWSGGEPVC--VDIDPPKI--------RCPHSREKMAEPEKLTARVYWDPPLVKD 212
CMEDG WS E +C + + PP + RC ++ K+ K +
Sbjct: 1329 CMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCK---------- 1378
Query: 213 SADGTITRVTLRGPEPGSHFPEGEHVIRYTAY------DRAYNRASCKFIVKVQVRRCPT 266
PG H P + A+ D ++ +C + C
Sbjct: 1379 ---------------PGYHVPGSSRKSKKRAFKTQCTQDGSWQEGACVPVT------CDP 1417
Query: 267 LKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRV--CQSSRQWSGSPPICAPMK 323
P HG CT+ G + + C C+ QG S V C+ W+GS +C M+
Sbjct: 1418 PPPKFHGLYQCTN-GFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQ 1475
>gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens]
Length = 3487
Score = 73.2 bits (178), Expect = 5e-13
Identities = 65/242 (26%), Positives = 90/242 (37%), Gaps = 30/242 (12%)
Query: 81 SSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTAY-CRQMRCHALPFITSGTYTCTNGV 139
S G SC+ G+ L+G R +C+ + WSG+ C C I +G N
Sbjct: 2674 SVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGHINGENYS 2733
Query: 140 LLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKL 199
S Y C++G+ L G RIC +D WSG P CV + C H
Sbjct: 2734 YRGSVV-YQCNAGFRLIGMSVRICQQDHHWSGKTPFCV-----LVSCGHPGS-------- 2779
Query: 200 TARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKV 259
PP + S D +R G G R D + S
Sbjct: 2780 -------PPHSQMSGDSYTVGAVVRYSCIGKRTLVGNST-RMCGLDGHWT-GSLPHCSGT 2830
Query: 260 QVRRCPTLKPPQHGYLTCTSAGDNY--GATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPP 317
V C P HG GD++ G + C+ G+ +G+ R CQ++ WSGS P
Sbjct: 2831 SVGVCGDPGIPAHGI----RLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQP 2886
Query: 318 IC 319
C
Sbjct: 2887 EC 2888
Score = 71.2 bits (173), Expect = 2e-12
Identities = 82/319 (25%), Positives = 122/319 (38%), Gaps = 49/319 (15%)
Query: 22 TPTWYAGSGYYPDESYNEVYAEEVPQAPALDYRVPRWCYTLNIQDGEATCYSPKGGNYHS 81
T Y+ S Y ++ E AE + + VP C + D + S + G +
Sbjct: 2551 TKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPD--VSSISVEHGRWRL 2608
Query: 82 SLGTRCE------LSCDRGFRLIGRRSVQCLPSRRWS---GTAYCRQMRCHALPFITSGT 132
T+ + L CD G+ G+R ++C + +WS T CR + C LP +G
Sbjct: 2609 IFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNGH 2668
Query: 133 YTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREK 192
T V + +SC+SGY L G R R CM +G WSG E +RC
Sbjct: 2669 RIGTLSVY-GATAIFSCNSGYTLVGSRVRECMANGLWSGSE----------VRC------ 2711
Query: 193 MAEPEKLTARVYWDPPLVKDSADGTITRVTLRGP---EPGSHFPEGEHVIRYTAYDRAYN 249
L P+V +G + RG + + F +R D ++
Sbjct: 2712 ------LAGHCGTPEPIVNGHING--ENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWS 2763
Query: 250 RASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNY--GATCEYHCDGGYDRQGTPSRVCQ 307
F V V C P H + +GD+Y GA Y C G G +R+C
Sbjct: 2764 -GKTPFCVLVS---CGHPGSPPHSQM----SGDSYTVGAVVRYSCIGKRTLVGNSTRMCG 2815
Query: 308 SSRQWSGSPPICAPMKINV 326
W+GS P C+ + V
Sbjct: 2816 LDGHWTGSLPHCSGTSVGV 2834
Score = 65.9 bits (159), Expect = 8e-11
Identities = 59/238 (24%), Positives = 88/238 (36%), Gaps = 35/238 (14%)
Query: 91 CDRGFRLIGRRS--VQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGVLLDSRCDY 147
C G+ + R + C R W+GT C+ + C P I +G ++ + S Y
Sbjct: 2978 CVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGSD-FMWGSSVTY 3036
Query: 148 SCSSGYHLEGDRSRICMEDGRWSGGEPVCVDI--DPPKIRCPHSREKMAEPEKLTARVYW 205
+C GY L C +G W+G P C + P + RE + +
Sbjct: 3037 ACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGDPGVPSRGRREDRGFSYRSSVSFSC 3096
Query: 206 DPPLVKDSADGTITRV--TLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRR 263
PPLV + + T G +P SC + +
Sbjct: 3097 HPPLVLVGSPRRFCQSDGTWSGTQP-----------------------SC---IDPTLTT 3130
Query: 264 CPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAP 321
C PQ G + S G G+T + C GY QG+ +R C + WSG+PP C P
Sbjct: 3131 CADPGVPQFG-IQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVP 3187
Score = 61.2 bits (147), Expect = 2e-09
Identities = 63/258 (24%), Positives = 100/258 (38%), Gaps = 42/258 (16%)
Query: 77 GNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRR----WS-GTAYCRQMRCHALPFITSG 131
G + G C+ G+RL+G C + WS C+ + C LP
Sbjct: 2481 GQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSC-GLPEAPKN 2539
Query: 132 TYTCTNGVLLDSRCDYSCSSGYHLE--GDRSRICMEDGRWSGGE--PVCVDI---DPPKI 184
+ ++ YSCS GYHL+ + + C++ G WS P CV + D I
Sbjct: 2540 GMVFGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSI 2599
Query: 185 RCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTA- 243
H R ++ + + L+ +PG ++ G+ VIR A
Sbjct: 2600 SVEHGRWRLI----FETQYQFQAQLMLIC-------------DPGYYY-TGQRVIRCQAN 2641
Query: 244 --YDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGT 301
+ + +C+ I C L P +G+ T + YGAT + C+ GY G+
Sbjct: 2642 GKWSLGDSTPTCRII------SCGELPIPPNGHRIGTLS--VYGATAIFSCNSGYTLVGS 2693
Query: 302 PSRVCQSSRQWSGSPPIC 319
R C ++ WSGS C
Sbjct: 2694 RVRECMANGLWSGSEVRC 2711
Score = 57.4 bits (137), Expect = 3e-08
Identities = 55/240 (22%), Positives = 93/240 (38%), Gaps = 26/240 (10%)
Query: 84 GTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGVLLD 142
GT SC+ G L G C + WSG+ C + C ++ ++G++
Sbjct: 2854 GTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFS 2913
Query: 143 SRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTAR 202
S Y C GY+ G SR C +G W+G +P C+ I+ P + ++ +
Sbjct: 2914 SSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPGIPANGLRLGNDFRY--- 2970
Query: 203 VYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVR 262
+ T+T + G SH + DR +N K + K +
Sbjct: 2971 ------------NKTVTYQCVPGYMMESH----RVSVLSCTKDRTWN--GTKPVCKALMC 3012
Query: 263 RCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPM 322
+ P L P +G + + +G++ Y C GY C+ + W+G P C P+
Sbjct: 3013 KPPPLIP--NGKV--VGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPV 3068
Score = 55.5 bits (132), Expect = 1e-07
Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 2/101 (1%)
Query: 83 LGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTAY-CRQMRCHALPFITSGTYTCTNGVLL 141
+G+ C +G+ L G + CLP+ WSGT C C T + +
Sbjct: 3150 VGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCRQPETPTHANVGALDLPSM 3209
Query: 142 DSRCDYSCSSGYHLEG-DRSRICMEDGRWSGGEPVCVDIDP 181
YSC G+ L+G R C DG W+G P+C+++ P
Sbjct: 3210 GYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEVRP 3250
Score = 45.1 bits (105), Expect = 1e-04
Identities = 55/250 (22%), Positives = 83/250 (33%), Gaps = 41/250 (16%)
Query: 84 GTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGVLLD 142
G+ +C G++L C + W+G C + C P + S G
Sbjct: 3031 GSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGD-PGVPSRGRREDRGFSYR 3089
Query: 143 SRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVD------IDP--PKIRCPHSREKMA 194
S +SC L G R C DG WSG +P C+D DP P+ ++ +
Sbjct: 3090 SSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFGIQNNSQGYQ 3149
Query: 195 EPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCK 254
+ R L + + +T G P
Sbjct: 3150 VGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPD------------------------- 3184
Query: 255 FIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYD-RQGTPSRVCQSSRQWS 313
V R+ T G L S G T Y C G+ + G+ R C++ W+
Sbjct: 3185 -CVPHHCRQPETPTHANVGALDLPSMG----YTLIYSCQEGFSLKGGSEHRTCKADGSWT 3239
Query: 314 GSPPICAPMK 323
G PPIC ++
Sbjct: 3240 GKPPICLEVR 3249
Score = 42.0 bits (97), Expect = 0.001
Identities = 33/112 (29%), Positives = 46/112 (41%), Gaps = 18/112 (16%)
Query: 75 KGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTAYCRQMRCHALPFITS---- 130
+G +Y SS+ SC L+G C WSGT Q C P +T+
Sbjct: 3084 RGFSYRSSVS----FSCHPPLVLVGSPRRFCQSDGTWSGT----QPSCID-PTLTTCADP 3134
Query: 131 -----GTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCV 177
G + G + S + C GY L+G +R C+ + WSG P CV
Sbjct: 3135 GVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCV 3186
Score = 34.7 bits (78), Expect = 0.19
Identities = 22/76 (28%), Positives = 35/76 (46%), Gaps = 5/76 (6%)
Query: 260 QVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQ--SSRQWSGSPP 317
+++ CP +P +G + AG N G + + C GY G P CQ ++R W P
Sbjct: 2119 ELQECPDPEPFANGIVR--GAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLP 2176
Query: 318 ICAPMKINVNVNSAAG 333
C + N+ S+ G
Sbjct: 2177 KC-EVPCGGNITSSNG 2191
Score = 32.7 bits (73), Expect = 0.72
Identities = 50/220 (22%), Positives = 77/220 (35%), Gaps = 43/220 (19%)
Query: 138 GVLLDSRCDYSCSSGYHLEGDRSRICMEDGR--WSGGEPVCVDIDPPKIRCPHSREKMAE 195
G S +SC GY L G +C+ R W P CV +R S + ++
Sbjct: 1227 GHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAECGGTVRGEVSGQVLSP 1286
Query: 196 ----PEKLTARVYW-----------------DPPLVKDSA---DGTITRVTLRGPEPGSH 231
P + W D V D DG + L G
Sbjct: 1287 GYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGPA 1346
Query: 232 FPEGEH------VIRY-TAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNY 284
P+ H V+++ T + + + +F V C PQ+G + +GD++
Sbjct: 1347 LPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATS-CNDPGIPQNG----SRSGDSW 1401
Query: 285 --GATCEYHCDGGYDRQGTPSRVC---QSSRQWSGSPPIC 319
G + + CD GY QG+ C ++ W SPP C
Sbjct: 1402 EAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTC 1441
Score = 32.3 bits (72), Expect = 0.94
Identities = 18/78 (23%), Positives = 34/78 (43%), Gaps = 10/78 (12%)
Query: 264 CPTLKPPQHGYLTCTSAGDNY--GATCEYHCDGGYDRQGTPSRVCQSSRQ----WSGSPP 317
CP P+ G G ++ G++ ++ C+ GYD QG+ C WS P
Sbjct: 343 CPDPGIPERG----KRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRP 398
Query: 318 ICAPMKINVNVNSAAGLL 335
+C + ++ +G++
Sbjct: 399 VCRARMCDAHLRGPSGII 416
Score = 32.3 bits (72), Expect = 0.94
Identities = 48/219 (21%), Positives = 80/219 (36%), Gaps = 42/219 (19%)
Query: 141 LDSRCDYSCSSGYHLEGDRSRICM--EDGR--WSGGEPVC-------------VDIDPPK 183
L S Y C GY +EG + C+ DG+ W+ PVC V + P
Sbjct: 1576 LGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAPCGGQYVGSDGVVLSPNY 1635
Query: 184 IR-------CPHSREKMAEPEKLTARVYWDPPL--VKDSADGTITRVTLRGPEPGSHFPE 234
+ C + + ++ L V + DG L GSH E
Sbjct: 1636 PQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQHSRLLSSLSGSHTGE 1695
Query: 235 -------GEHVIRYTAYDRAYNRA---SCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNY 284
+ +I+++A A R + + + +C ++ P++G + +
Sbjct: 1696 SLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSATQCSSVPEPRYG--KRLGSDFSV 1753
Query: 285 GATCEYHCDGGYDRQGTPSRVC----QSSRQWSGSPPIC 319
GA + C+ GY QG+P C + QW+ S P C
Sbjct: 1754 GAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTC 1792
Score = 32.0 bits (71), Expect = 1.2
Identities = 11/37 (29%), Positives = 19/37 (51%)
Query: 283 NYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
++G T ++ C ++ G + CQ + QWS P C
Sbjct: 538 HHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGC 574
Score = 30.8 bits (68), Expect = 2.7
Identities = 14/40 (35%), Positives = 20/40 (50%), Gaps = 4/40 (10%)
Query: 141 LDSRCDYSCSSGYHLEGDRSRICME----DGRWSGGEPVC 176
L S ++C+ GY L+G + CM+ WS PVC
Sbjct: 361 LGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVC 400
Score = 30.4 bits (67), Expect = 3.6
Identities = 17/59 (28%), Positives = 25/59 (42%), Gaps = 3/59 (5%)
Query: 263 RCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSS--RQWSGSPPIC 319
+C P+ GY G G++ + CD GY +G+ +C S R W P C
Sbjct: 1210 KCEDPGTPKFGYKV-HDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTC 1267
Score = 29.3 bits (64), Expect = 7.9
Identities = 9/31 (29%), Positives = 17/31 (54%)
Query: 147 YSCSSGYHLEGDRSRICMEDGRWSGGEPVCV 177
+ C + L G ++ C ++ +WS +P CV
Sbjct: 545 FECQPAFELVGQKAITCQKNNQWSAKKPGCV 575
>gi|42544177 complement component (3d/Epstein Barr virus) receptor 2
isoform 2 [Homo sapiens]
Length = 1033
Score = 72.8 bits (177), Expect = 6e-13
Identities = 77/326 (23%), Positives = 112/326 (34%), Gaps = 61/326 (18%)
Query: 70 TCYSPKGGNYHSSLGTRCEL---SCDRGFRLIGRRSVQCLPSRR---WSGTAYCRQMRCH 123
TC + G+R EL SC G++L G C + + C+ + CH
Sbjct: 661 TCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCH 720
Query: 124 ALPFITSGTYT--CTNGVLLDSRCDYSCSSGYHLEGDRSRICMED----GRWSGGEPVCV 177
P I +G +T L + Y C G++L G++ C D G WSG P C+
Sbjct: 721 PPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCL 780
Query: 178 DIDPPKIRCPHSREKMAEPEKLTARVYWDPPLVK-DSADG-------------------- 216
PP RCP+ K T Y +V D G
Sbjct: 781 R-SPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPG 839
Query: 217 --TITRVTLRGPEPGSHFPEGEH----VIRYT-AYDRAYNRASCKFIVKVQVRRCP---- 265
T + G P P G H + R++ Y+ +V + C
Sbjct: 840 VPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGT 899
Query: 266 -TLKPPQHGYLTCTSAGD--------------NYGATCEYHCDGGYDRQGTPSRVCQSSR 310
+ P + C+S D YGA C+ GY +G+P CQS
Sbjct: 900 WSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDH 959
Query: 311 QWSGSPPICAPMKI-NVNVNSAAGLL 335
QW+ +C + V AAGL+
Sbjct: 960 QWNPPLAVCRSRSLAPVLCGIAAGLI 985
Score = 58.2 bits (139), Expect = 2e-08
Identities = 64/282 (22%), Positives = 100/282 (35%), Gaps = 54/282 (19%)
Query: 90 SCDRGFRLIGRRSVQCLPSRRWSGTAYCRQMRCHALPFITSGTYTCTNGVLLD--SRCDY 147
+C GF L G + ++C W +A + C A P I +G + V D + Y
Sbjct: 378 ACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKY 437
Query: 148 SCSSGYHLEGDRSRICMEDGRWSGGEPVC------------VDIDPPKIRCPHSREKMAE 195
SC+ GY L G+ S C +G W+ P C + + P E
Sbjct: 438 SCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGE 497
Query: 196 PEKLTARVYWD---------------------PPLVKDSA-----------DGTITRVTL 223
KL+ VY + PP++ + A T+T
Sbjct: 498 GYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCN 557
Query: 224 RGPEPGSHFP-EGEHVIRYTAYDRAYNRAS-----CKFIVKVQVRRCPTLKPPQHGYLTC 277
GPE G F GE IR T+ D+ S CK + + +C + ++
Sbjct: 558 PGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCK--LSLLAVQCSHVHIANGYKISG 615
Query: 278 TSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
A Y T + C G+ +G+ C++ W P+C
Sbjct: 616 KEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVC 657
Score = 57.4 bits (137), Expect = 3e-08
Identities = 62/258 (24%), Positives = 96/258 (37%), Gaps = 48/258 (18%)
Query: 84 GTRCELSCDRGFRLIGRRSVQCLPSRRWSGTAYCR-----QMRCHALPFITSGTYTCTN- 137
G +C F + G +SV C + W T + C ALP I +G +T N
Sbjct: 111 GDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENV 170
Query: 138 -GVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKI-RCPHSREKMAE 195
+ YSC SGY L G++ C+ G+WS P C + + R P+ + K
Sbjct: 171 GSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVK--- 227
Query: 196 PEKLTARVYWDPPLVKDSADGTI---TRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRAS 252
+PP+++ L+GP P S + +T
Sbjct: 228 ----------EPPILRVGVTANFFCDEGYRLQGP-PSSRCVIAGQGVAWT------KMPV 270
Query: 253 CKFIVKVQVRRCPTLKPPQHG-YLTCTSAGDNYGATCEYHCDGGYDRQ------GTPSRV 305
C+ I CP+ P +G ++ + A +YG+ Y CD + G +
Sbjct: 271 CEEIF------CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLR 324
Query: 306 C----QSSRQWSGSPPIC 319
C Q + WSG P C
Sbjct: 325 CTVDSQKTGTWSGPAPRC 342
Score = 45.8 bits (107), Expect = 8e-05
Identities = 32/121 (26%), Positives = 54/121 (44%), Gaps = 16/121 (13%)
Query: 83 LGTRCELSCDRGFRLIGRRSVQCLPSRR---WSGTAYCRQMRCHALPFITSGTY------ 133
+G CD G+RL G S +C+ + + W+ C ++ C + P I +G +
Sbjct: 234 VGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLA 293
Query: 134 TCTNGVLLDSRCDYSCSSG--YHLEGDRSRICMED----GRWSGGEPVCVDIDPPKIRCP 187
+ G ++ CD G + L G+ + C D G WSG P C ++ ++CP
Sbjct: 294 NVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRC-ELSTSAVQCP 352
Query: 188 H 188
H
Sbjct: 353 H 353
Score = 43.1 bits (100), Expect = 5e-04
Identities = 59/262 (22%), Positives = 91/262 (34%), Gaps = 56/262 (21%)
Query: 82 SLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTAYCRQMRCHALPFITS-------GTYT 134
++GT SC FRLIG +S+ C+ + GT +C +S G Y
Sbjct: 42 AVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKYSSCPEPIVPGGYK 101
Query: 135 CTNGVLL--DSRCDYSCSSGYHLEGDRSRICMEDGRWSGGE-PVCVDIDPPKIRCP---- 187
++C + + + G++S C + W P CV + P + CP
Sbjct: 102 IRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVFP--LECPALPM 159
Query: 188 -HSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVI------R 240
H+ +E V A G + + GE +I +
Sbjct: 160 IHNGHHTSEN-------------VGSIAPGLSVTYSCE----SGYLLVGEKIINCLSSGK 202
Query: 241 YTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQG 300
++A A CK + R P K + L G T + CD GY QG
Sbjct: 203 WSAVPPTCEEARCK-----SLGRFPNGKVKEPPIL-------RVGVTANFFCDEGYRLQG 250
Query: 301 TPSRVCQSSRQ---WSGSPPIC 319
PS C + Q W+ P+C
Sbjct: 251 PPSSRCVIAGQGVAWT-KMPVC 271
Score = 40.8 bits (94), Expect = 0.003
Identities = 71/305 (23%), Positives = 107/305 (35%), Gaps = 70/305 (22%)
Query: 78 NYHSSLGTRCELSCDRG--FRLIGRRSVQCLPSRRWSGTAYCRQMRCHALPFITSGTYTC 135
+Y S + C+ + G F LIG +++C + +GT RC +++ C
Sbjct: 296 SYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCE----LSTSAVQC 351
Query: 136 TNGVLLDSRCD--------------YSCSSGYHLEGDRSRICMEDGRWSGGEPVC----- 176
+ +L R ++C G+ L+G + C G W PVC
Sbjct: 352 PHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQ 411
Query: 177 ---------------VDIDPP---KIRCPHSREKMAEPE-KLTARVYWDPPL--VKDSAD 215
V DP K C + E + T+ W PP+ K +A
Sbjct: 412 APPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAAC 471
Query: 216 GTITRVTLRGPE-----PGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCP--TLK 268
R L P+ P + GE Y Y +++R C T
Sbjct: 472 EATGRQLLTKPQHQFVRPDVNSSCGE---GYKLSGSVYQECQGTIPWFMEIRLCKEITCP 528
Query: 269 PP---QHGYLTCTSAGD-NYGATCEYHCDGGYDRQ------GTPSRVCQSSRQ----WSG 314
PP +G T +S D YG T Y C+ G +R G + C S+ Q WSG
Sbjct: 529 PPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSG 588
Query: 315 SPPIC 319
P+C
Sbjct: 589 PAPLC 593
>gi|41152076 steroid-sensitive protein 1 [Homo sapiens]
Length = 950
Score = 69.7 bits (169), Expect = 5e-12
Identities = 41/138 (29%), Positives = 75/138 (54%), Gaps = 14/138 (10%)
Query: 330 SAAGLLDQFYEKQRLLIISAPDPSNRYYKMQISMLQQSTCGLDLRHVTIIELVGQPPQEV 389
S L +F ++RLL+ISAP+ + Y Q+S L C LRH+TI++L+G +EV
Sbjct: 767 SLENFLSRFRWRRRLLVISAPNDEDWAYSQQLSALSGQACNFGLRHITILKLLG-VGEEV 825
Query: 390 GRIRE------------QQLSANIIEELRQFQRLTRSYFNMVLIDKQGIDRDRYMEPV-T 436
G + E + + A++++++R + +++ YF+M+L+ K G + Y P+ +
Sbjct: 826 GGVLELFPINGSSVVEREDVPAHLVKDIRNYFQVSPEYFSMLLVGKDGNVKSWYPSPMWS 885
Query: 437 PEEIFTFIDDYLLSNQEL 454
++ ID L QE+
Sbjct: 886 MVIVYDLIDSMQLRRQEM 903
Score = 66.6 bits (161), Expect = 4e-11
Identities = 43/127 (33%), Positives = 66/127 (51%), Gaps = 10/127 (7%)
Query: 329 NSAAGLLDQFYEKQRLLIISAPDPSNRYYKMQISMLQQST-CGLDLRHVTIIELVGQPPQ 387
+S+ +L F K R+ +ISAP S YY++ +S+L+ C L RH+ I L Q +
Sbjct: 136 SSSPNILASFAGKNRVWVISAPHASEGYYRLMMSLLKDDVYCELAERHIQQIVLFHQAGE 195
Query: 388 EVGRIR---------EQQLSANIIEELRQFQRLTRSYFNMVLIDKQGIDRDRYMEPVTPE 438
E G++R EQ L ++I +L F +L + F MVL+ K +RY PV E
Sbjct: 196 EGGKVRRITSEGQILEQPLDPSLIPKLMSFLKLEKGKFGMVLLKKTLQVEERYPYPVRLE 255
Query: 439 EIFTFID 445
++ ID
Sbjct: 256 AMYEVID 262
Score = 58.2 bits (139), Expect = 2e-08
Identities = 40/151 (26%), Positives = 69/151 (45%), Gaps = 15/151 (9%)
Query: 330 SAAGLLDQFYEKQRLLIISAPDPSNRYYKMQISMLQQSTCGLDLRHVTIIELVGQPPQEV 389
S A LL F K+RLL+I+AP N Y Q +S C + R +++I + G
Sbjct: 611 SVADLLGSFEGKRRLLLITAPKAENNMYVQQRDEYLESFCKMATRKISVITIFGPVNNST 670
Query: 390 GRIREQQL---------------SANIIEELRQFQRLTRSYFNMVLIDKQGIDRDRYMEP 434
+I QL +I ELR+ +T + F MVL D + Y P
Sbjct: 671 MKIDHFQLDNEKPMRVVDDEDLVDQRLISELRKEYGMTYNDFFMVLTDVDLRVKQYYEVP 730
Query: 435 VTPEEIFTFIDDYLLSNQELTQRREQRDICE 465
+T + +F ID + +++ +++++ +C+
Sbjct: 731 ITMKSVFDLIDTFQSRIKDMEKQKKEGIVCK 761
>gi|41152074 steroid-sensitive protein 1 [Homo sapiens]
Length = 950
Score = 69.7 bits (169), Expect = 5e-12
Identities = 41/138 (29%), Positives = 75/138 (54%), Gaps = 14/138 (10%)
Query: 330 SAAGLLDQFYEKQRLLIISAPDPSNRYYKMQISMLQQSTCGLDLRHVTIIELVGQPPQEV 389
S L +F ++RLL+ISAP+ + Y Q+S L C LRH+TI++L+G +EV
Sbjct: 767 SLENFLSRFRWRRRLLVISAPNDEDWAYSQQLSALSGQACNFGLRHITILKLLG-VGEEV 825
Query: 390 GRIRE------------QQLSANIIEELRQFQRLTRSYFNMVLIDKQGIDRDRYMEPV-T 436
G + E + + A++++++R + +++ YF+M+L+ K G + Y P+ +
Sbjct: 826 GGVLELFPINGSSVVEREDVPAHLVKDIRNYFQVSPEYFSMLLVGKDGNVKSWYPSPMWS 885
Query: 437 PEEIFTFIDDYLLSNQEL 454
++ ID L QE+
Sbjct: 886 MVIVYDLIDSMQLRRQEM 903
Score = 66.6 bits (161), Expect = 4e-11
Identities = 43/127 (33%), Positives = 66/127 (51%), Gaps = 10/127 (7%)
Query: 329 NSAAGLLDQFYEKQRLLIISAPDPSNRYYKMQISMLQQST-CGLDLRHVTIIELVGQPPQ 387
+S+ +L F K R+ +ISAP S YY++ +S+L+ C L RH+ I L Q +
Sbjct: 136 SSSPNILASFAGKNRVWVISAPHASEGYYRLMMSLLKDDVYCELAERHIQQIVLFHQAGE 195
Query: 388 EVGRIR---------EQQLSANIIEELRQFQRLTRSYFNMVLIDKQGIDRDRYMEPVTPE 438
E G++R EQ L ++I +L F +L + F MVL+ K +RY PV E
Sbjct: 196 EGGKVRRITSEGQILEQPLDPSLIPKLMSFLKLEKGKFGMVLLKKTLQVEERYPYPVRLE 255
Query: 439 EIFTFID 445
++ ID
Sbjct: 256 AMYEVID 262
Score = 58.2 bits (139), Expect = 2e-08
Identities = 40/151 (26%), Positives = 69/151 (45%), Gaps = 15/151 (9%)
Query: 330 SAAGLLDQFYEKQRLLIISAPDPSNRYYKMQISMLQQSTCGLDLRHVTIIELVGQPPQEV 389
S A LL F K+RLL+I+AP N Y Q +S C + R +++I + G
Sbjct: 611 SVADLLGSFEGKRRLLLITAPKAENNMYVQQRDEYLESFCKMATRKISVITIFGPVNNST 670
Query: 390 GRIREQQL---------------SANIIEELRQFQRLTRSYFNMVLIDKQGIDRDRYMEP 434
+I QL +I ELR+ +T + F MVL D + Y P
Sbjct: 671 MKIDHFQLDNEKPMRVVDDEDLVDQRLISELRKEYGMTYNDFFMVLTDVDLRVKQYYEVP 730
Query: 435 VTPEEIFTFIDDYLLSNQELTQRREQRDICE 465
+T + +F ID + +++ +++++ +C+
Sbjct: 731 ITMKSVFDLIDTFQSRIKDMEKQKKEGIVCK 761
>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sapiens]
Length = 3667
Score = 68.2 bits (165), Expect = 2e-11
Identities = 63/265 (23%), Positives = 91/265 (34%), Gaps = 36/265 (13%)
Query: 66 DGEATCYSP----KGGNYHSSLGTRCEL--SCDRGFRLIGRRSVQCLPSRRWSGTA-YCR 118
D TC P G S+ T+ + +CD G+ L G CL + W+G C+
Sbjct: 3011 DATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECK 3070
Query: 119 QMRCHALPFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVD 178
++C +G +G S YSC GY L G R C +G WSG P C
Sbjct: 3071 AVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTI 3130
Query: 179 IDPPKIRCPHSREKMAEPEKLTARVYW--DPPLVKDSADGTITRVTLRGPEPGSHFPEGE 236
I P + + + + V + P + I T+ G G
Sbjct: 3131 ISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGV------ 3184
Query: 237 HVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGY 296
+C+ + CPT PPQ ++G + Y C GY
Sbjct: 3185 -------------MPTCRAVT------CPT--PPQISNGRLEGTNFDWGFSISYICSPGY 3223
Query: 297 DRQGTPSRVCQSSRQWSGSPPICAP 321
+ C + WSG P C P
Sbjct: 3224 ELSFPAVLTCVGNGTWSGEVPQCLP 3248
Score = 65.5 bits (158), Expect = 1e-10
Identities = 71/280 (25%), Positives = 101/280 (36%), Gaps = 48/280 (17%)
Query: 90 SCDRGFRLIGRRSVQCLPS----RRWSGTA-YCRQMRCHALPFITSGTYTCTNGVLLDSR 144
+CDRGFRL+G+ S C S W C+ + C +P + T L+ +R
Sbjct: 2555 ACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISC-GIPKAPTNGGILTTDYLVGTR 2613
Query: 145 CDYSCSSGYHLEGDR--SRICMEDGRWSGGE--PVCVDIDPPKIRC---PHSREKMAEP- 196
Y C+ GY L + +C DG WS P CV + P I H R ++
Sbjct: 2614 VTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHGRWRIVNGS 2673
Query: 197 --EKLTARVYWDPPLVKDSADGTITRV-----TLRGPEPGSHF---------PEGEHVIR 240
E T V+ P +I + + R P P G +
Sbjct: 2674 HYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGT 2733
Query: 241 YTAY-DRAYNRASCKF-IVKVQVRRCPTLKPPQHGYLTCTSA--------------GDNY 284
T+Y A F +V VR C + C + G+NY
Sbjct: 2734 QTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGENY 2793
Query: 285 GA--TCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPM 322
G T Y C+ G+ G+ R+CQ WSG P C P+
Sbjct: 2794 GYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPV 2833
Score = 60.8 bits (146), Expect = 2e-09
Identities = 64/244 (26%), Positives = 87/244 (35%), Gaps = 31/244 (12%)
Query: 83 LGTRCELSCDRGF--RLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGV 139
+G C G+ L G R C + WSG CR + C P I++G TN
Sbjct: 3151 VGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFD 3210
Query: 140 LLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVD--IDPPKIRCPHSREKMAEPE 197
S Y CS GY L C+ +G WSG P C+ P I RE +
Sbjct: 3211 WGFS-ISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIY 3269
Query: 198 KLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIV 257
+ + P + G+ TR+ G+ H I T
Sbjct: 3270 QSEVSFSCNFPFI---LVGSSTRIC---QADGTWSGSSPHCIEPTQTS------------ 3311
Query: 258 KVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPP 317
C P+HG T G G+ ++HC G+ QG+ +R C WSG P
Sbjct: 3312 ------CENPGVPRHGSQNNTF-GFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQP 3364
Query: 318 ICAP 321
C P
Sbjct: 3365 ECIP 3368
Score = 60.5 bits (145), Expect = 3e-09
Identities = 63/266 (23%), Positives = 91/266 (34%), Gaps = 58/266 (21%)
Query: 73 SPKGGNY---HSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGT-AYCRQMRCHALPFI 128
+P GN +S G+ +CD GF L+G +CL S WS + C C I
Sbjct: 2724 TPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELI 2783
Query: 129 TSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPH 188
+G N D+ Y C+ G+ L G RIC +D WSG P CV + C H
Sbjct: 2784 VNGQVIGENYGYRDTVV-YQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVS-----CGH 2837
Query: 189 SREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAY 248
+ G G+ F + V+ ++
Sbjct: 2838 PGS------------------------------PIYGRTSGNGFNFND-VVTFSCNIGYL 2866
Query: 249 NRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAG---------------DNYGATCEYHCD 293
+ K + Q R + PP + C+ G YG Y C+
Sbjct: 2867 MQGPTK--AQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCN 2924
Query: 294 GGYDRQGTPSRVCQSSRQWSGSPPIC 319
GY G+ +CQ + QW P C
Sbjct: 2925 PGYFLFGSSVLICQPNGQWDKPLPEC 2950
Score = 57.4 bits (137), Expect = 3e-08
Identities = 32/101 (31%), Positives = 46/101 (45%), Gaps = 4/101 (3%)
Query: 80 HSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWS---GTAYCRQMRCHALPFITSGTYTCT 136
H T+ SCD G+ +G S++CLP+ WS YC+ + C LP +G T
Sbjct: 2674 HYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGT 2733
Query: 137 NGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCV 177
S ++C G+ L G R C+ G WS E C+
Sbjct: 2734 Q-TSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCL 2773
Score = 53.9 bits (128), Expect = 3e-07
Identities = 56/231 (24%), Positives = 82/231 (35%), Gaps = 25/231 (10%)
Query: 91 CDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGVLLDSRCDYSC 149
C G+ L + C+ + WSG C C P I + + S +SC
Sbjct: 3219 CSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGD-PGIPAQGKREGKSFIYQSEVSFSC 3277
Query: 150 SSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTARVYWDPPL 209
+ + L G +RIC DG WSG P C I+P + C + + T +
Sbjct: 3278 NFPFILVGSSTRICQADGTWSGSSPHC--IEPTQTSCENPGVPRHGSQNNTFGFQVGSVV 3335
Query: 210 VKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKP 269
G + L+G + P+ + ++ SCK +
Sbjct: 3336 QFHCKKGHL----LQGSTTRTCLPD----LTWSGIQPECIPHSCKQPETPAHANVVGMDL 3387
Query: 270 PQHGYLTCTSAGDNYGATCEYHCDGGYD-RQGTPSRVCQSSRQWSGSPPIC 319
P HGY T Y C G+ GT RVC+S W+G PIC
Sbjct: 3388 PSHGY------------TLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPIC 3426
Score = 52.8 bits (125), Expect = 7e-07
Identities = 55/240 (22%), Positives = 82/240 (34%), Gaps = 40/240 (16%)
Query: 90 SCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCH--ALPF-------ITSGTYTCTNGV 139
SC+ G+ + G QC +R+WS C+ + C +P I G +T V
Sbjct: 2860 SCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVV 2919
Query: 140 LLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKL 199
Y C+ GY L G IC +G+W P C+ ID P + E
Sbjct: 2920 F------YDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTF 2973
Query: 200 TARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKV 259
+ V++ + + L G GS P T D
Sbjct: 2974 GSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQ-PHCSGDATGTCGD-------------- 3018
Query: 260 QVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
P G+ + + +T Y CD GY G+ R C ++ W+G P C
Sbjct: 3019 ---------PGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPEC 3069
Score = 51.6 bits (122), Expect = 1e-06
Identities = 74/330 (22%), Positives = 112/330 (33%), Gaps = 49/330 (14%)
Query: 56 PRWCYTLNIQDGEATCYSPKG-----GNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRR 110
P C +N D S + GN+ + GT C+ G+ L G + C P+ +
Sbjct: 2885 PPMCKVVNCSDPGIPANSKRESKIEHGNF--TYGTVVFYDCNPGYFLFGSSVLICQPNGQ 2942
Query: 111 WSGTA-YCRQMRCHALPFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRW 169
W C + C P + S YSC+ L G SR C +G W
Sbjct: 2943 WDKPLPECIMIDC-GHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHW 3001
Query: 170 SGGEPVCV-----DIDPPKIRCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLR 224
SG +P C P SR++ K T R D T L
Sbjct: 3002 SGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACD------------TGYILH 3049
Query: 225 GPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNY 284
G E + G R + CK + +C +G + G +
Sbjct: 3050 GSEERTCLANGSWTGR---------QPECKAV------QCGNPGTTANGKVFRID-GTTF 3093
Query: 285 GATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPMKINVNVNSAAGLL--DQFYEKQ 342
++ Y C GY G R C ++ WSG+ P C + A GL D + Q
Sbjct: 3094 SSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQ 3153
Query: 343 RLLIISAPDPSNRYYKMQISMLQQSTCGLD 372
+ + P Y M+++ + TC ++
Sbjct: 3154 NVSYMCQPG-----YTMELNGSRIRTCTIN 3178
Score = 50.1 bits (118), Expect = 4e-06
Identities = 42/168 (25%), Positives = 69/168 (41%), Gaps = 35/168 (20%)
Query: 38 NEVYAEEVPQAPALDYRVPRWCYTLNI-----QDGEATCYSPKGGNYHSSLGTRCELSCD 92
N ++ EVPQ +P++C I ++G++ Y + SC+
Sbjct: 3236 NGTWSGEVPQC------LPKFCGDPGIPAQGKREGKSFIYQ-----------SEVSFSCN 3278
Query: 93 RGFRLIGRRSVQCLPSRRWSGTA-YC---RQMRCHALPFITSGTYTCTNGVLLDSRCDYS 148
F L+G + C WSG++ +C Q C G+ T G + S +
Sbjct: 3279 FPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFH 3338
Query: 149 CSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEP 196
C G+ L+G +R C+ D WSG +P C+ PHS ++ P
Sbjct: 3339 CKKGHLLQGSTTRTCLPDLTWSGIQPECI---------PHSCKQPETP 3377
Score = 45.8 bits (107), Expect = 8e-05
Identities = 37/159 (23%), Positives = 65/159 (40%), Gaps = 22/159 (13%)
Query: 64 IQDGEATCYSP-------KGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTAY 116
I+ + +C +P + + +G+ + C +G L G + CLP WSG
Sbjct: 3305 IEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGI-- 3362
Query: 117 CRQMRC--HALPFITSGTYTCTNGVLLDSR---CDYSCSSGYHLEGDRS-RICMEDGRWS 170
Q C H+ + + G+ L S Y+C G+ L G R+C D W+
Sbjct: 3363 --QPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWT 3420
Query: 171 GGEPVC-----VDIDPPKIRCPHSREKMAEPEKLTARVY 204
G P+C + + P+ K++ P+ + A+ Y
Sbjct: 3421 GKVPICEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNY 3459
Score = 39.3 bits (90), Expect = 0.008
Identities = 49/211 (23%), Positives = 79/211 (37%), Gaps = 45/211 (21%)
Query: 147 YSCSSGYHLEGDRSRICMEDGRWSGGEPVCV---------------DIDPPK-------- 183
+ C G+ L G++S +C E+ +WS P+C+ D P+
Sbjct: 648 FECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNC 707
Query: 184 ----IRCPHSREKMAEPEKLTARVYWDPPLVK--DSADGTITRVTLRGPEPGSHFPEGEH 237
I P SR ++ + +D VK DS + I T G E SH H
Sbjct: 708 IWTIISDPGSRIHLSFND-FDLESQFDFLAVKDGDSPESPILG-TFTGAEVPSHLTSNSH 765
Query: 238 VIRYTAYDRAYNRASCKFIVKVQV---RRCPTLKPPQHGYLTCTSAGDNY--GATCEYHC 292
++R + ++ + F + CP P + GDN+ G++ C
Sbjct: 766 ILR-LEFQADHSMSGRGFNITYNTFGHNECPDPGIP----INARRFGDNFQLGSSISVIC 820
Query: 293 DGGYDR-QGTPSRVC---QSSRQWSGSPPIC 319
+ G+ + QGT + C WSG P C
Sbjct: 821 EEGFIKTQGTETITCILMDGKVMWSGLIPKC 851
Score = 38.1 bits (87), Expect = 0.017
Identities = 50/208 (24%), Positives = 74/208 (35%), Gaps = 38/208 (18%)
Query: 147 YSCSSGYHLEGDRSRICMEDGR--WSGGEPVCVD-------------IDP-------PKI 184
+SCSSGY LEG IC+ GR WS P CV + P
Sbjct: 1166 FSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNH 1225
Query: 185 RCPHSREKMA-EPEKLTARVY----WDPPLVKDSAD------GTITRVTLRGPEPGSHFP 233
C +S + A + ++AR + D + D D G T ++RG S
Sbjct: 1226 ECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSS--T 1283
Query: 234 EGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCD 293
+ + + + + ++ C PQ GY + G G+T Y C+
Sbjct: 1284 SNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGY-KISDQGHFAGSTIIYGCN 1342
Query: 294 GGYDRQGTPSRVCQSS--RQWSGSPPIC 319
GY G+ C + R W P C
Sbjct: 1343 PGYTLHGSSLLKCMTGERRAWDYPLPSC 1370
Score = 38.1 bits (87), Expect = 0.017
Identities = 58/228 (25%), Positives = 78/228 (34%), Gaps = 38/228 (16%)
Query: 147 YSCSSGYHLEGDRSRICMEDGR--WSGGEPVCVDIDPPKIRCPHSREKMAE----PEKLT 200
Y C+ GY L G CM R W P C+ + + S ++ P
Sbjct: 1339 YGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNN 1398
Query: 201 ARVYW----DPPLVKD--------SADGTITRVTLRGPE--------PGSHFPEGEHV-- 238
R W DP + A I RV PE GS PEG H
Sbjct: 1399 LRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTL 1458
Query: 239 -IRYTAYDRAYNRASCKFIVKVQ---VRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDG 294
I +D + + F ++ C P +G T G G T + CD
Sbjct: 1459 NIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNG--TRNGDGREPGDTVVFQCDP 1516
Query: 295 GYDRQGTPSRVC---QSSRQWSGSPPIC-APMKINVNVNSAAGLLDQF 338
GY+ QG C ++ W SPP+C AP N+ +S L F
Sbjct: 1517 GYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNF 1564
Score = 35.8 bits (81), Expect = 0.085
Identities = 23/96 (23%), Positives = 36/96 (37%), Gaps = 7/96 (7%)
Query: 235 GEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDG 294
G V + D N+ F ++ C T + P HGY+ + G + + CD
Sbjct: 2502 GHEVFLQWSADHGNNKKG--FRIRYIAFYCSTPESPPHGYII-SQTGGQLNSVVRWACDR 2558
Query: 295 GYDRQGTPSRVCQSS----RQWSGSPPICAPMKINV 326
G+ G S VC+ S W P C + +
Sbjct: 2559 GFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGI 2594
Score = 35.0 bits (79), Expect = 0.14
Identities = 21/81 (25%), Positives = 33/81 (40%), Gaps = 6/81 (7%)
Query: 257 VKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQ----W 312
+K CP P++G + + G+T ++ CD Y QG S CQ + W
Sbjct: 439 IKTASNLCPDPGEPENGKRI--GSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAW 496
Query: 313 SGSPPICAPMKINVNVNSAAG 333
S P+C N+ +G
Sbjct: 497 SDHRPVCKVKTCGSNLQGPSG 517
Score = 32.7 bits (73), Expect = 0.72
Identities = 20/60 (33%), Positives = 24/60 (40%), Gaps = 8/60 (13%)
Query: 264 CPTLKPPQHGYLTCTSAGDNY--GATCEYHCDGGYDRQGTPSRVCQSS--RQWSGSPPIC 319
CP + P G GD Y G + CD GY QG C R+W+ PIC
Sbjct: 2012 CPEPQTPSSGI----KIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC 2067
Score = 32.3 bits (72), Expect = 0.94
Identities = 51/246 (20%), Positives = 81/246 (32%), Gaps = 65/246 (26%)
Query: 128 ITSGTYTCTNGVL------------LDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPV 175
+T TY+C + + + S +SC SGY L + +C ++ WS P
Sbjct: 963 VTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPT 1022
Query: 176 C--------------------VDIDPPKIRC------PHSREKMAEPEKLTARVYWDPPL 209
C + P + C H + + D L
Sbjct: 1023 CDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLL 1082
Query: 210 VKDSADGT--ITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQ------- 260
+ ++ T + R+T GS P + Y + RA R F + +
Sbjct: 1083 ITENGSFTQPLARLT------GSDLPPTINAGLYGNF-RAQLRFISDFSISYEGFNITFS 1135
Query: 261 ---VRRCPTLKPPQHGYLTCTSAGDNYGA--TCEYHCDGGYDRQGTPSRVCQSS--RQWS 313
+ C PQ+G + G N+G T + C GY +GT +C R WS
Sbjct: 1136 EYNLEPCEDPGIPQYG----SRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWS 1191
Query: 314 GSPPIC 319
P C
Sbjct: 1192 APLPRC 1197
>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
sapiens]
Length = 3538
Score = 68.2 bits (165), Expect = 2e-11
Identities = 63/265 (23%), Positives = 91/265 (34%), Gaps = 36/265 (13%)
Query: 66 DGEATCYSP----KGGNYHSSLGTRCEL--SCDRGFRLIGRRSVQCLPSRRWSGTA-YCR 118
D TC P G S+ T+ + +CD G+ L G CL + W+G C+
Sbjct: 2882 DATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECK 2941
Query: 119 QMRCHALPFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVD 178
++C +G +G S YSC GY L G R C +G WSG P C
Sbjct: 2942 AVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTI 3001
Query: 179 IDPPKIRCPHSREKMAEPEKLTARVYW--DPPLVKDSADGTITRVTLRGPEPGSHFPEGE 236
I P + + + + V + P + I T+ G G
Sbjct: 3002 ISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGV------ 3055
Query: 237 HVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGY 296
+C+ + CPT PPQ ++G + Y C GY
Sbjct: 3056 -------------MPTCRAVT------CPT--PPQISNGRLEGTNFDWGFSISYICSPGY 3094
Query: 297 DRQGTPSRVCQSSRQWSGSPPICAP 321
+ C + WSG P C P
Sbjct: 3095 ELSFPAVLTCVGNGTWSGEVPQCLP 3119
Score = 64.7 bits (156), Expect = 2e-10
Identities = 62/244 (25%), Positives = 90/244 (36%), Gaps = 41/244 (16%)
Query: 90 SCDRGFRLIGRRSVQCLPS----RRWSG-TAYCRQMRCHALPFITSGTYTCTNGVLLDSR 144
+CDRGFRL+G+ S C S W C+ + C +P + T L+ +R
Sbjct: 2491 ACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISC-GIPKAPTNGGILTTDYLVGTR 2549
Query: 145 CDYSCSSGYHLEGDR--SRICMEDGRWSGGE--PVCVDIDPPKIRCPHSREKMAEPEKLT 200
Y C+ GY L + +C DG WS P CV I ++ P + K+ T
Sbjct: 2550 VTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNGNKIG-----T 2604
Query: 201 ARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQ 260
Y + + +R + E E A + + IV Q
Sbjct: 2605 QTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESE------TRCLAGHCGIPELIVNGQ 2658
Query: 261 VRRCPTLKPPQHGYLTCTSAGDNYG--ATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPI 318
V G+NYG T Y C+ G+ G+ R+CQ WSG P
Sbjct: 2659 V------------------IGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPS 2700
Query: 319 CAPM 322
C P+
Sbjct: 2701 CVPV 2704
Score = 60.8 bits (146), Expect = 2e-09
Identities = 64/244 (26%), Positives = 87/244 (35%), Gaps = 31/244 (12%)
Query: 83 LGTRCELSCDRGF--RLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGV 139
+G C G+ L G R C + WSG CR + C P I++G TN
Sbjct: 3022 VGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFD 3081
Query: 140 LLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVD--IDPPKIRCPHSREKMAEPE 197
S Y CS GY L C+ +G WSG P C+ P I RE +
Sbjct: 3082 WGFS-ISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIY 3140
Query: 198 KLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIV 257
+ + P + G+ TR+ G+ H I T
Sbjct: 3141 QSEVSFSCNFPFI---LVGSSTRIC---QADGTWSGSSPHCIEPTQTS------------ 3182
Query: 258 KVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPP 317
C P+HG T G G+ ++HC G+ QG+ +R C WSG P
Sbjct: 3183 ------CENPGVPRHGSQNNTF-GFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQP 3235
Query: 318 ICAP 321
C P
Sbjct: 3236 ECIP 3239
Score = 60.5 bits (145), Expect = 3e-09
Identities = 63/266 (23%), Positives = 91/266 (34%), Gaps = 58/266 (21%)
Query: 73 SPKGGNY---HSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGT-AYCRQMRCHALPFI 128
+P GN +S G+ +CD GF L+G +CL S WS + C C I
Sbjct: 2595 TPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELI 2654
Query: 129 TSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPH 188
+G N D+ Y C+ G+ L G RIC +D WSG P CV + C H
Sbjct: 2655 VNGQVIGENYGYRDTVV-YQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVS-----CGH 2708
Query: 189 SREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAY 248
+ G G+ F + V+ ++
Sbjct: 2709 PGS------------------------------PIYGRTSGNGFNFND-VVTFSCNIGYL 2737
Query: 249 NRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAG---------------DNYGATCEYHCD 293
+ K + Q R + PP + C+ G YG Y C+
Sbjct: 2738 MQGPTK--AQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCN 2795
Query: 294 GGYDRQGTPSRVCQSSRQWSGSPPIC 319
GY G+ +CQ + QW P C
Sbjct: 2796 PGYFLFGSSVLICQPNGQWDKPLPEC 2821
Score = 53.9 bits (128), Expect = 3e-07
Identities = 56/231 (24%), Positives = 82/231 (35%), Gaps = 25/231 (10%)
Query: 91 CDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGVLLDSRCDYSC 149
C G+ L + C+ + WSG C C P I + + S +SC
Sbjct: 3090 CSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGD-PGIPAQGKREGKSFIYQSEVSFSC 3148
Query: 150 SSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTARVYWDPPL 209
+ + L G +RIC DG WSG P C I+P + C + + T +
Sbjct: 3149 NFPFILVGSSTRICQADGTWSGSSPHC--IEPTQTSCENPGVPRHGSQNNTFGFQVGSVV 3206
Query: 210 VKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKP 269
G + L+G + P+ + ++ SCK +
Sbjct: 3207 QFHCKKGHL----LQGSTTRTCLPD----LTWSGIQPECIPHSCKQPETPAHANVVGMDL 3258
Query: 270 PQHGYLTCTSAGDNYGATCEYHCDGGYD-RQGTPSRVCQSSRQWSGSPPIC 319
P HGY T Y C G+ GT RVC+S W+G PIC
Sbjct: 3259 PSHGY------------TLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPIC 3297
Score = 52.8 bits (125), Expect = 7e-07
Identities = 55/240 (22%), Positives = 82/240 (34%), Gaps = 40/240 (16%)
Query: 90 SCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCH--ALPF-------ITSGTYTCTNGV 139
SC+ G+ + G QC +R+WS C+ + C +P I G +T V
Sbjct: 2731 SCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVV 2790
Query: 140 LLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKL 199
Y C+ GY L G IC +G+W P C+ ID P + E
Sbjct: 2791 F------YDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTF 2844
Query: 200 TARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKV 259
+ V++ + + L G GS P T D
Sbjct: 2845 GSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQ-PHCSGDATGTCGD-------------- 2889
Query: 260 QVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
P G+ + + +T Y CD GY G+ R C ++ W+G P C
Sbjct: 2890 ---------PGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPEC 2940
Score = 51.6 bits (122), Expect = 1e-06
Identities = 74/330 (22%), Positives = 112/330 (33%), Gaps = 49/330 (14%)
Query: 56 PRWCYTLNIQDGEATCYSPKG-----GNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRR 110
P C +N D S + GN+ + GT C+ G+ L G + C P+ +
Sbjct: 2756 PPMCKVVNCSDPGIPANSKRESKIEHGNF--TYGTVVFYDCNPGYFLFGSSVLICQPNGQ 2813
Query: 111 WSGTA-YCRQMRCHALPFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRW 169
W C + C P + S YSC+ L G SR C +G W
Sbjct: 2814 WDKPLPECIMIDC-GHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHW 2872
Query: 170 SGGEPVCV-----DIDPPKIRCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLR 224
SG +P C P SR++ K T R D T L
Sbjct: 2873 SGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACD------------TGYILH 2920
Query: 225 GPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNY 284
G E + G R + CK + +C +G + G +
Sbjct: 2921 GSEERTCLANGSWTGR---------QPECKAV------QCGNPGTTANGKVFRID-GTTF 2964
Query: 285 GATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPMKINVNVNSAAGLL--DQFYEKQ 342
++ Y C GY G R C ++ WSG+ P C + A GL D + Q
Sbjct: 2965 SSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQ 3024
Query: 343 RLLIISAPDPSNRYYKMQISMLQQSTCGLD 372
+ + P Y M+++ + TC ++
Sbjct: 3025 NVSYMCQPG-----YTMELNGSRIRTCTIN 3049
Score = 50.1 bits (118), Expect = 4e-06
Identities = 42/168 (25%), Positives = 69/168 (41%), Gaps = 35/168 (20%)
Query: 38 NEVYAEEVPQAPALDYRVPRWCYTLNI-----QDGEATCYSPKGGNYHSSLGTRCELSCD 92
N ++ EVPQ +P++C I ++G++ Y + SC+
Sbjct: 3107 NGTWSGEVPQC------LPKFCGDPGIPAQGKREGKSFIYQ-----------SEVSFSCN 3149
Query: 93 RGFRLIGRRSVQCLPSRRWSGTA-YC---RQMRCHALPFITSGTYTCTNGVLLDSRCDYS 148
F L+G + C WSG++ +C Q C G+ T G + S +
Sbjct: 3150 FPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFH 3209
Query: 149 CSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEP 196
C G+ L+G +R C+ D WSG +P C+ PHS ++ P
Sbjct: 3210 CKKGHLLQGSTTRTCLPDLTWSGIQPECI---------PHSCKQPETP 3248
Score = 45.8 bits (107), Expect = 8e-05
Identities = 37/159 (23%), Positives = 65/159 (40%), Gaps = 22/159 (13%)
Query: 64 IQDGEATCYSP-------KGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTAY 116
I+ + +C +P + + +G+ + C +G L G + CLP WSG
Sbjct: 3176 IEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGI-- 3233
Query: 117 CRQMRC--HALPFITSGTYTCTNGVLLDSR---CDYSCSSGYHLEGDRS-RICMEDGRWS 170
Q C H+ + + G+ L S Y+C G+ L G R+C D W+
Sbjct: 3234 --QPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWT 3291
Query: 171 GGEPVC-----VDIDPPKIRCPHSREKMAEPEKLTARVY 204
G P+C + + P+ K++ P+ + A+ Y
Sbjct: 3292 GKVPICEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNY 3330
Score = 39.3 bits (90), Expect = 0.008
Identities = 49/211 (23%), Positives = 79/211 (37%), Gaps = 45/211 (21%)
Query: 147 YSCSSGYHLEGDRSRICMEDGRWSGGEPVCV---------------DIDPPK-------- 183
+ C G+ L G++S +C E+ +WS P+C+ D P+
Sbjct: 584 FECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNC 643
Query: 184 ----IRCPHSREKMAEPEKLTARVYWDPPLVK--DSADGTITRVTLRGPEPGSHFPEGEH 237
I P SR ++ + +D VK DS + I T G E SH H
Sbjct: 644 IWTIISDPGSRIHLSFND-FDLESQFDFLAVKDGDSPESPILG-TFTGAEVPSHLTSNSH 701
Query: 238 VIRYTAYDRAYNRASCKFIVKVQV---RRCPTLKPPQHGYLTCTSAGDNY--GATCEYHC 292
++R + ++ + F + CP P + GDN+ G++ C
Sbjct: 702 ILR-LEFQADHSMSGRGFNITYNTFGHNECPDPGIP----INARRFGDNFQLGSSISVIC 756
Query: 293 DGGYDR-QGTPSRVC---QSSRQWSGSPPIC 319
+ G+ + QGT + C WSG P C
Sbjct: 757 EEGFIKTQGTETITCILMDGKVMWSGLIPKC 787
Score = 38.1 bits (87), Expect = 0.017
Identities = 50/208 (24%), Positives = 74/208 (35%), Gaps = 38/208 (18%)
Query: 147 YSCSSGYHLEGDRSRICMEDGR--WSGGEPVCVD-------------IDP-------PKI 184
+SCSSGY LEG IC+ GR WS P CV + P
Sbjct: 1102 FSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNH 1161
Query: 185 RCPHSREKMA-EPEKLTARVY----WDPPLVKDSAD------GTITRVTLRGPEPGSHFP 233
C +S + A + ++AR + D + D D G T ++RG S
Sbjct: 1162 ECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSS--T 1219
Query: 234 EGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCD 293
+ + + + + ++ C PQ GY + G G+T Y C+
Sbjct: 1220 SNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGY-KISDQGHFAGSTIIYGCN 1278
Query: 294 GGYDRQGTPSRVCQSS--RQWSGSPPIC 319
GY G+ C + R W P C
Sbjct: 1279 PGYTLHGSSLLKCMTGERRAWDYPLPSC 1306
Score = 38.1 bits (87), Expect = 0.017
Identities = 58/228 (25%), Positives = 78/228 (34%), Gaps = 38/228 (16%)
Query: 147 YSCSSGYHLEGDRSRICMEDGR--WSGGEPVCVDIDPPKIRCPHSREKMAE----PEKLT 200
Y C+ GY L G CM R W P C+ + + S ++ P
Sbjct: 1275 YGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNN 1334
Query: 201 ARVYW----DPPLVKD--------SADGTITRVTLRGPE--------PGSHFPEGEHV-- 238
R W DP + A I RV PE GS PEG H
Sbjct: 1335 LRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTL 1394
Query: 239 -IRYTAYDRAYNRASCKFIVKVQ---VRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDG 294
I +D + + F ++ C P +G T G G T + CD
Sbjct: 1395 NIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNG--TRNGDGREPGDTVVFQCDP 1452
Query: 295 GYDRQGTPSRVC---QSSRQWSGSPPIC-APMKINVNVNSAAGLLDQF 338
GY+ QG C ++ W SPP+C AP N+ +S L F
Sbjct: 1453 GYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNF 1500
Score = 35.8 bits (81), Expect = 0.085
Identities = 23/96 (23%), Positives = 36/96 (37%), Gaps = 7/96 (7%)
Query: 235 GEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDG 294
G V + D N+ F ++ C T + P HGY+ + G + + CD
Sbjct: 2438 GHEVFLQWSADHGNNKKG--FRIRYIAFYCSTPESPPHGYII-SQTGGQLNSVVRWACDR 2494
Query: 295 GYDRQGTPSRVCQSS----RQWSGSPPICAPMKINV 326
G+ G S VC+ S W P C + +
Sbjct: 2495 GFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGI 2530
Score = 35.0 bits (79), Expect = 0.14
Identities = 21/81 (25%), Positives = 33/81 (40%), Gaps = 6/81 (7%)
Query: 257 VKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQ----W 312
+K CP P++G + + G+T ++ CD Y QG S CQ + W
Sbjct: 375 IKTASNLCPDPGEPENGKRI--GSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAW 432
Query: 313 SGSPPICAPMKINVNVNSAAG 333
S P+C N+ +G
Sbjct: 433 SDHRPVCKVKTCGSNLQGPSG 453
Score = 32.7 bits (73), Expect = 0.72
Identities = 20/60 (33%), Positives = 24/60 (40%), Gaps = 8/60 (13%)
Query: 264 CPTLKPPQHGYLTCTSAGDNY--GATCEYHCDGGYDRQGTPSRVCQSS--RQWSGSPPIC 319
CP + P G GD Y G + CD GY QG C R+W+ PIC
Sbjct: 1948 CPEPQTPSSGI----KIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC 2003
Score = 32.3 bits (72), Expect = 0.94
Identities = 51/246 (20%), Positives = 81/246 (32%), Gaps = 65/246 (26%)
Query: 128 ITSGTYTCTNGVL------------LDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPV 175
+T TY+C + + + S +SC SGY L + +C ++ WS P
Sbjct: 899 VTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPT 958
Query: 176 C--------------------VDIDPPKIRC------PHSREKMAEPEKLTARVYWDPPL 209
C + P + C H + + D L
Sbjct: 959 CDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLL 1018
Query: 210 VKDSADGT--ITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQ------- 260
+ ++ T + R+T GS P + Y + RA R F + +
Sbjct: 1019 ITENGSFTQPLARLT------GSDLPPTINAGLYGNF-RAQLRFISDFSISYEGFNITFS 1071
Query: 261 ---VRRCPTLKPPQHGYLTCTSAGDNYGA--TCEYHCDGGYDRQGTPSRVCQSS--RQWS 313
+ C PQ+G + G N+G T + C GY +GT +C R WS
Sbjct: 1072 EYNLEPCEDPGIPQYG----SRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWS 1127
Query: 314 GSPPIC 319
P C
Sbjct: 1128 APLPRC 1133
>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sapiens]
Length = 3707
Score = 68.2 bits (165), Expect = 2e-11
Identities = 63/265 (23%), Positives = 91/265 (34%), Gaps = 36/265 (13%)
Query: 66 DGEATCYSP----KGGNYHSSLGTRCEL--SCDRGFRLIGRRSVQCLPSRRWSGTA-YCR 118
D TC P G S+ T+ + +CD G+ L G CL + W+G C+
Sbjct: 3051 DATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECK 3110
Query: 119 QMRCHALPFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVD 178
++C +G +G S YSC GY L G R C +G WSG P C
Sbjct: 3111 AVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTI 3170
Query: 179 IDPPKIRCPHSREKMAEPEKLTARVYW--DPPLVKDSADGTITRVTLRGPEPGSHFPEGE 236
I P + + + + V + P + I T+ G G
Sbjct: 3171 ISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGV------ 3224
Query: 237 HVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGY 296
+C+ + CPT PPQ ++G + Y C GY
Sbjct: 3225 -------------MPTCRAVT------CPT--PPQISNGRLEGTNFDWGFSISYICSPGY 3263
Query: 297 DRQGTPSRVCQSSRQWSGSPPICAP 321
+ C + WSG P C P
Sbjct: 3264 ELSFPAVLTCVGNGTWSGEVPQCLP 3288
Score = 65.5 bits (158), Expect = 1e-10
Identities = 71/280 (25%), Positives = 101/280 (36%), Gaps = 48/280 (17%)
Query: 90 SCDRGFRLIGRRSVQCLPS----RRWSGTA-YCRQMRCHALPFITSGTYTCTNGVLLDSR 144
+CDRGFRL+G+ S C S W C+ + C +P + T L+ +R
Sbjct: 2595 ACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISC-GIPKAPTNGGILTTDYLVGTR 2653
Query: 145 CDYSCSSGYHLEGDR--SRICMEDGRWSGGE--PVCVDIDPPKIRC---PHSREKMAEP- 196
Y C+ GY L + +C DG WS P CV + P I H R ++
Sbjct: 2654 VTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHGRWRIVNGS 2713
Query: 197 --EKLTARVYWDPPLVKDSADGTITRV-----TLRGPEPGSHF---------PEGEHVIR 240
E T V+ P +I + + R P P G +
Sbjct: 2714 HYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGT 2773
Query: 241 YTAY-DRAYNRASCKF-IVKVQVRRCPTLKPPQHGYLTCTSA--------------GDNY 284
T+Y A F +V VR C + C + G+NY
Sbjct: 2774 QTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGENY 2833
Query: 285 GA--TCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPM 322
G T Y C+ G+ G+ R+CQ WSG P C P+
Sbjct: 2834 GYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPV 2873
Score = 60.8 bits (146), Expect = 2e-09
Identities = 64/244 (26%), Positives = 87/244 (35%), Gaps = 31/244 (12%)
Query: 83 LGTRCELSCDRGF--RLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGV 139
+G C G+ L G R C + WSG CR + C P I++G TN
Sbjct: 3191 VGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFD 3250
Query: 140 LLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVD--IDPPKIRCPHSREKMAEPE 197
S Y CS GY L C+ +G WSG P C+ P I RE +
Sbjct: 3251 WGFS-ISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIY 3309
Query: 198 KLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIV 257
+ + P + G+ TR+ G+ H I T
Sbjct: 3310 QSEVSFSCNFPFI---LVGSSTRIC---QADGTWSGSSPHCIEPTQTS------------ 3351
Query: 258 KVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPP 317
C P+HG T G G+ ++HC G+ QG+ +R C WSG P
Sbjct: 3352 ------CENPGVPRHGSQNNTF-GFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQP 3404
Query: 318 ICAP 321
C P
Sbjct: 3405 ECIP 3408
Score = 60.5 bits (145), Expect = 3e-09
Identities = 63/266 (23%), Positives = 91/266 (34%), Gaps = 58/266 (21%)
Query: 73 SPKGGNY---HSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGT-AYCRQMRCHALPFI 128
+P GN +S G+ +CD GF L+G +CL S WS + C C I
Sbjct: 2764 TPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELI 2823
Query: 129 TSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPH 188
+G N D+ Y C+ G+ L G RIC +D WSG P CV + C H
Sbjct: 2824 VNGQVIGENYGYRDTVV-YQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVS-----CGH 2877
Query: 189 SREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAY 248
+ G G+ F + V+ ++
Sbjct: 2878 PGS------------------------------PIYGRTSGNGFNFND-VVTFSCNIGYL 2906
Query: 249 NRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAG---------------DNYGATCEYHCD 293
+ K + Q R + PP + C+ G YG Y C+
Sbjct: 2907 MQGPTK--AQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCN 2964
Query: 294 GGYDRQGTPSRVCQSSRQWSGSPPIC 319
GY G+ +CQ + QW P C
Sbjct: 2965 PGYFLFGSSVLICQPNGQWDKPLPEC 2990
Score = 57.4 bits (137), Expect = 3e-08
Identities = 32/101 (31%), Positives = 46/101 (45%), Gaps = 4/101 (3%)
Query: 80 HSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWS---GTAYCRQMRCHALPFITSGTYTCT 136
H T+ SCD G+ +G S++CLP+ WS YC+ + C LP +G T
Sbjct: 2714 HYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGT 2773
Query: 137 NGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCV 177
S ++C G+ L G R C+ G WS E C+
Sbjct: 2774 Q-TSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCL 2813
Score = 53.9 bits (128), Expect = 3e-07
Identities = 56/231 (24%), Positives = 82/231 (35%), Gaps = 25/231 (10%)
Query: 91 CDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGVLLDSRCDYSC 149
C G+ L + C+ + WSG C C P I + + S +SC
Sbjct: 3259 CSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGD-PGIPAQGKREGKSFIYQSEVSFSC 3317
Query: 150 SSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTARVYWDPPL 209
+ + L G +RIC DG WSG P C I+P + C + + T +
Sbjct: 3318 NFPFILVGSSTRICQADGTWSGSSPHC--IEPTQTSCENPGVPRHGSQNNTFGFQVGSVV 3375
Query: 210 VKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKP 269
G + L+G + P+ + ++ SCK +
Sbjct: 3376 QFHCKKGHL----LQGSTTRTCLPD----LTWSGIQPECIPHSCKQPETPAHANVVGMDL 3427
Query: 270 PQHGYLTCTSAGDNYGATCEYHCDGGYD-RQGTPSRVCQSSRQWSGSPPIC 319
P HGY T Y C G+ GT RVC+S W+G PIC
Sbjct: 3428 PSHGY------------TLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPIC 3466
Score = 52.8 bits (125), Expect = 7e-07
Identities = 55/240 (22%), Positives = 82/240 (34%), Gaps = 40/240 (16%)
Query: 90 SCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCH--ALPF-------ITSGTYTCTNGV 139
SC+ G+ + G QC +R+WS C+ + C +P I G +T V
Sbjct: 2900 SCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVV 2959
Query: 140 LLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKL 199
Y C+ GY L G IC +G+W P C+ ID P + E
Sbjct: 2960 F------YDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTF 3013
Query: 200 TARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKV 259
+ V++ + + L G GS P T D
Sbjct: 3014 GSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQ-PHCSGDATGTCGD-------------- 3058
Query: 260 QVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
P G+ + + +T Y CD GY G+ R C ++ W+G P C
Sbjct: 3059 ---------PGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPEC 3109
Score = 51.6 bits (122), Expect = 1e-06
Identities = 74/330 (22%), Positives = 112/330 (33%), Gaps = 49/330 (14%)
Query: 56 PRWCYTLNIQDGEATCYSPKG-----GNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRR 110
P C +N D S + GN+ + GT C+ G+ L G + C P+ +
Sbjct: 2925 PPMCKVVNCSDPGIPANSKRESKIEHGNF--TYGTVVFYDCNPGYFLFGSSVLICQPNGQ 2982
Query: 111 WSGTA-YCRQMRCHALPFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRW 169
W C + C P + S YSC+ L G SR C +G W
Sbjct: 2983 WDKPLPECIMIDC-GHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHW 3041
Query: 170 SGGEPVCV-----DIDPPKIRCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLR 224
SG +P C P SR++ K T R D T L
Sbjct: 3042 SGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACD------------TGYILH 3089
Query: 225 GPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNY 284
G E + G R + CK + +C +G + G +
Sbjct: 3090 GSEERTCLANGSWTGR---------QPECKAV------QCGNPGTTANGKVFRID-GTTF 3133
Query: 285 GATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPMKINVNVNSAAGLL--DQFYEKQ 342
++ Y C GY G R C ++ WSG+ P C + A GL D + Q
Sbjct: 3134 SSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQ 3193
Query: 343 RLLIISAPDPSNRYYKMQISMLQQSTCGLD 372
+ + P Y M+++ + TC ++
Sbjct: 3194 NVSYMCQPG-----YTMELNGSRIRTCTIN 3218
Score = 50.1 bits (118), Expect = 4e-06
Identities = 42/168 (25%), Positives = 69/168 (41%), Gaps = 35/168 (20%)
Query: 38 NEVYAEEVPQAPALDYRVPRWCYTLNI-----QDGEATCYSPKGGNYHSSLGTRCELSCD 92
N ++ EVPQ +P++C I ++G++ Y + SC+
Sbjct: 3276 NGTWSGEVPQC------LPKFCGDPGIPAQGKREGKSFIYQ-----------SEVSFSCN 3318
Query: 93 RGFRLIGRRSVQCLPSRRWSGTA-YC---RQMRCHALPFITSGTYTCTNGVLLDSRCDYS 148
F L+G + C WSG++ +C Q C G+ T G + S +
Sbjct: 3319 FPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFH 3378
Query: 149 CSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEP 196
C G+ L+G +R C+ D WSG +P C+ PHS ++ P
Sbjct: 3379 CKKGHLLQGSTTRTCLPDLTWSGIQPECI---------PHSCKQPETP 3417
Score = 45.8 bits (107), Expect = 8e-05
Identities = 37/159 (23%), Positives = 65/159 (40%), Gaps = 22/159 (13%)
Query: 64 IQDGEATCYSP-------KGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTAY 116
I+ + +C +P + + +G+ + C +G L G + CLP WSG
Sbjct: 3345 IEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGI-- 3402
Query: 117 CRQMRC--HALPFITSGTYTCTNGVLLDSR---CDYSCSSGYHLEGDRS-RICMEDGRWS 170
Q C H+ + + G+ L S Y+C G+ L G R+C D W+
Sbjct: 3403 --QPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWT 3460
Query: 171 GGEPVC-----VDIDPPKIRCPHSREKMAEPEKLTARVY 204
G P+C + + P+ K++ P+ + A+ Y
Sbjct: 3461 GKVPICEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNY 3499
Score = 39.3 bits (90), Expect = 0.008
Identities = 49/211 (23%), Positives = 79/211 (37%), Gaps = 45/211 (21%)
Query: 147 YSCSSGYHLEGDRSRICMEDGRWSGGEPVCV---------------DIDPPK-------- 183
+ C G+ L G++S +C E+ +WS P+C+ D P+
Sbjct: 688 FECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNC 747
Query: 184 ----IRCPHSREKMAEPEKLTARVYWDPPLVK--DSADGTITRVTLRGPEPGSHFPEGEH 237
I P SR ++ + +D VK DS + I T G E SH H
Sbjct: 748 IWTIISDPGSRIHLSFND-FDLESQFDFLAVKDGDSPESPILG-TFTGAEVPSHLTSNSH 805
Query: 238 VIRYTAYDRAYNRASCKFIVKVQV---RRCPTLKPPQHGYLTCTSAGDNY--GATCEYHC 292
++R + ++ + F + CP P + GDN+ G++ C
Sbjct: 806 ILR-LEFQADHSMSGRGFNITYNTFGHNECPDPGIP----INARRFGDNFQLGSSISVIC 860
Query: 293 DGGYDR-QGTPSRVC---QSSRQWSGSPPIC 319
+ G+ + QGT + C WSG P C
Sbjct: 861 EEGFIKTQGTETITCILMDGKVMWSGLIPKC 891
Score = 38.1 bits (87), Expect = 0.017
Identities = 50/208 (24%), Positives = 74/208 (35%), Gaps = 38/208 (18%)
Query: 147 YSCSSGYHLEGDRSRICMEDGR--WSGGEPVCVD-------------IDP-------PKI 184
+SCSSGY LEG IC+ GR WS P CV + P
Sbjct: 1206 FSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNH 1265
Query: 185 RCPHSREKMA-EPEKLTARVY----WDPPLVKDSAD------GTITRVTLRGPEPGSHFP 233
C +S + A + ++AR + D + D D G T ++RG S
Sbjct: 1266 ECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSS--T 1323
Query: 234 EGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCD 293
+ + + + + ++ C PQ GY + G G+T Y C+
Sbjct: 1324 SNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGY-KISDQGHFAGSTIIYGCN 1382
Query: 294 GGYDRQGTPSRVCQSS--RQWSGSPPIC 319
GY G+ C + R W P C
Sbjct: 1383 PGYTLHGSSLLKCMTGERRAWDYPLPSC 1410
Score = 38.1 bits (87), Expect = 0.017
Identities = 58/228 (25%), Positives = 78/228 (34%), Gaps = 38/228 (16%)
Query: 147 YSCSSGYHLEGDRSRICMEDGR--WSGGEPVCVDIDPPKIRCPHSREKMAE----PEKLT 200
Y C+ GY L G CM R W P C+ + + S ++ P
Sbjct: 1379 YGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNN 1438
Query: 201 ARVYW----DPPLVKD--------SADGTITRVTLRGPE--------PGSHFPEGEHV-- 238
R W DP + A I RV PE GS PEG H
Sbjct: 1439 LRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTL 1498
Query: 239 -IRYTAYDRAYNRASCKFIVKVQ---VRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDG 294
I +D + + F ++ C P +G T G G T + CD
Sbjct: 1499 NIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNG--TRNGDGREPGDTVVFQCDP 1556
Query: 295 GYDRQGTPSRVC---QSSRQWSGSPPIC-APMKINVNVNSAAGLLDQF 338
GY+ QG C ++ W SPP+C AP N+ +S L F
Sbjct: 1557 GYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNF 1604
Score = 35.8 bits (81), Expect = 0.085
Identities = 23/96 (23%), Positives = 36/96 (37%), Gaps = 7/96 (7%)
Query: 235 GEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDG 294
G V + D N+ F ++ C T + P HGY+ + G + + CD
Sbjct: 2542 GHEVFLQWSADHGNNKKG--FRIRYIAFYCSTPESPPHGYII-SQTGGQLNSVVRWACDR 2598
Query: 295 GYDRQGTPSRVCQSS----RQWSGSPPICAPMKINV 326
G+ G S VC+ S W P C + +
Sbjct: 2599 GFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGI 2634
Score = 35.0 bits (79), Expect = 0.14
Identities = 21/81 (25%), Positives = 33/81 (40%), Gaps = 6/81 (7%)
Query: 257 VKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQ----W 312
+K CP P++G + + G+T ++ CD Y QG S CQ + W
Sbjct: 479 IKTASNLCPDPGEPENGKRI--GSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAW 536
Query: 313 SGSPPICAPMKINVNVNSAAG 333
S P+C N+ +G
Sbjct: 537 SDHRPVCKVKTCGSNLQGPSG 557
Score = 32.7 bits (73), Expect = 0.72
Identities = 20/60 (33%), Positives = 24/60 (40%), Gaps = 8/60 (13%)
Query: 264 CPTLKPPQHGYLTCTSAGDNY--GATCEYHCDGGYDRQGTPSRVCQSS--RQWSGSPPIC 319
CP + P G GD Y G + CD GY QG C R+W+ PIC
Sbjct: 2052 CPEPQTPSSGI----KIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC 2107
Score = 32.3 bits (72), Expect = 0.94
Identities = 51/246 (20%), Positives = 81/246 (32%), Gaps = 65/246 (26%)
Query: 128 ITSGTYTCTNGVL------------LDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPV 175
+T TY+C + + + S +SC SGY L + +C ++ WS P
Sbjct: 1003 VTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPT 1062
Query: 176 C--------------------VDIDPPKIRC------PHSREKMAEPEKLTARVYWDPPL 209
C + P + C H + + D L
Sbjct: 1063 CDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLL 1122
Query: 210 VKDSADGT--ITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQ------- 260
+ ++ T + R+T GS P + Y + RA R F + +
Sbjct: 1123 ITENGSFTQPLARLT------GSDLPPTINAGLYGNF-RAQLRFISDFSISYEGFNITFS 1175
Query: 261 ---VRRCPTLKPPQHGYLTCTSAGDNYGA--TCEYHCDGGYDRQGTPSRVCQSS--RQWS 313
+ C PQ+G + G N+G T + C GY +GT +C R WS
Sbjct: 1176 EYNLEPCEDPGIPQYG----SRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWS 1231
Query: 314 GSPPIC 319
P C
Sbjct: 1232 APLPRC 1237
>gi|4506875 selectin L precursor [Homo sapiens]
Length = 372
Score = 60.8 bits (146), Expect = 2e-09
Identities = 35/118 (29%), Positives = 48/118 (40%), Gaps = 7/118 (5%)
Query: 67 GEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHAL 125
G C P G + S ++C SC G L G C P WS C+ ++C L
Sbjct: 206 GTMDCTHPLG---NFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPL 262
Query: 126 PFITSGTYTCTNGVL---LDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDID 180
G C++ + S C + CS G L G + IC G WS P+C +D
Sbjct: 263 SAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLD 320
Score = 42.0 bits (97), Expect = 0.001
Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 3/71 (4%)
Query: 120 MRCHALPFITSGTYTCTNGV---LLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVC 176
++C L GT CT+ + S+C +SCS G +L G C G WS EP C
Sbjct: 195 IQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTC 254
Query: 177 VDIDPPKIRCP 187
I + P
Sbjct: 255 QVIQCEPLSAP 265
Score = 42.0 bits (97), Expect = 0.001
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 2/62 (3%)
Query: 260 QVRRCPTLKPPQHGYLTCTS--AGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPP 317
QV +C L P G + C+ A ++ + C + C G + G +C+SS WS P
Sbjct: 255 QVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSP 314
Query: 318 IC 319
IC
Sbjct: 315 IC 316
Score = 38.9 bits (89), Expect = 0.010
Identities = 20/77 (25%), Positives = 31/77 (40%), Gaps = 7/77 (9%)
Query: 245 DRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYG--ATCEYHCDGGYDRQGTP 302
D Y C+F+++ C L+ P+ G + CT N+ + C + C G + G
Sbjct: 183 DVGYYGPQCQFVIQ-----CEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIE 237
Query: 303 SRVCQSSRQWSGSPPIC 319
C WS P C
Sbjct: 238 ETTCGPFGNWSSPEPTC 254
>gi|62912468 complement component 4 binding protein, beta chain
isoform 1 precursor [Homo sapiens]
Length = 252
Score = 58.2 bits (139), Expect = 2e-08
Identities = 28/95 (29%), Positives = 49/95 (51%), Gaps = 4/95 (4%)
Query: 91 CDRGFRLIGRRSVQCLPSRRWSGTAY-CRQMRCHALPFITSGTYTCTNGVLLDSRCDYSC 149
C +G+ L+G++++ C S+ W T CR C P + +G ++ + V + + + C
Sbjct: 49 CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPD-PVLVNGEFSSSGPVNVSDKITFMC 107
Query: 150 SSGYHLEGDRSRICMEDGRWSGGEPVCV--DIDPP 182
+ Y L+G C+ED W+ P+C D DPP
Sbjct: 108 NDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPP 142
Score = 42.4 bits (98), Expect = 0.001
Identities = 33/111 (29%), Positives = 44/111 (39%), Gaps = 4/111 (3%)
Query: 91 CDRGFRLIGRRSVQCLPSRRWSGT-AYCRQMRCHALPFITSGTYTCTNGVLLDSRCDYSC 149
C+ + L G QCL W+ C+ C G Y N L S Y C
Sbjct: 107 CNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHG-YFEGNNFTLGSTISYYC 165
Query: 150 SSGYHLEGDRSRICMEDGRWSGGEPVCVDI-DPPKIRCPHSREKMAEPEKL 199
Y+L G + + C+ DG WS PVC I + PK C + E + L
Sbjct: 166 EDRYYLVGVQEQQCV-DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNL 215
Score = 36.2 bits (82), Expect = 0.065
Identities = 50/213 (23%), Positives = 72/213 (33%), Gaps = 59/213 (27%)
Query: 122 CHALPFITSGTYTC--TNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDI 179
C LP + + + G +L + Y C GYHL G ++ C W C
Sbjct: 23 CPELPPVDNSIFVAKEVEGQILGT---YVCIKGYHLVGKKTLFCNASKEWDNTTTEC--- 76
Query: 180 DPPKIRCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSH---FPEGE 236
CP DP LV + GP S F +
Sbjct: 77 --RLGHCP------------------DPVLVNGEFSSS-------GPVNVSDKITFMCND 109
Query: 237 HVIRYTAYDRAYNRASC--------KFIVKVQVRRCPTLKPPQHGYLTCTSAGDNY--GA 286
H I + NR+ C F + + R C P HGY G+N+ G+
Sbjct: 110 HYIL-----KGSNRSQCLEDHTWAPPFPI-CKSRDCDPPGNPVHGYFE----GNNFTLGS 159
Query: 287 TCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
T Y+C+ Y G + C +WS + P+C
Sbjct: 160 TISYYCEDRYYLVGVQEQQCVDG-EWSSALPVC 191
>gi|62912466 complement component 4 binding protein, beta chain
isoform 2 precursor [Homo sapiens]
Length = 251
Score = 58.2 bits (139), Expect = 2e-08
Identities = 28/95 (29%), Positives = 49/95 (51%), Gaps = 4/95 (4%)
Query: 91 CDRGFRLIGRRSVQCLPSRRWSGTAY-CRQMRCHALPFITSGTYTCTNGVLLDSRCDYSC 149
C +G+ L+G++++ C S+ W T CR C P + +G ++ + V + + + C
Sbjct: 48 CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPD-PVLVNGEFSSSGPVNVSDKITFMC 106
Query: 150 SSGYHLEGDRSRICMEDGRWSGGEPVCV--DIDPP 182
+ Y L+G C+ED W+ P+C D DPP
Sbjct: 107 NDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPP 141
Score = 42.4 bits (98), Expect = 0.001
Identities = 33/111 (29%), Positives = 44/111 (39%), Gaps = 4/111 (3%)
Query: 91 CDRGFRLIGRRSVQCLPSRRWSGT-AYCRQMRCHALPFITSGTYTCTNGVLLDSRCDYSC 149
C+ + L G QCL W+ C+ C G Y N L S Y C
Sbjct: 106 CNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHG-YFEGNNFTLGSTISYYC 164
Query: 150 SSGYHLEGDRSRICMEDGRWSGGEPVCVDI-DPPKIRCPHSREKMAEPEKL 199
Y+L G + + C+ DG WS PVC I + PK C + E + L
Sbjct: 165 EDRYYLVGVQEQQCV-DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNL 214
Score = 36.2 bits (82), Expect = 0.065
Identities = 50/213 (23%), Positives = 72/213 (33%), Gaps = 59/213 (27%)
Query: 122 CHALPFITSGTYTC--TNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDI 179
C LP + + + G +L + Y C GYHL G ++ C W C
Sbjct: 22 CPELPPVDNSIFVAKEVEGQILGT---YVCIKGYHLVGKKTLFCNASKEWDNTTTEC--- 75
Query: 180 DPPKIRCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSH---FPEGE 236
CP DP LV + GP S F +
Sbjct: 76 --RLGHCP------------------DPVLVNGEFSSS-------GPVNVSDKITFMCND 108
Query: 237 HVIRYTAYDRAYNRASC--------KFIVKVQVRRCPTLKPPQHGYLTCTSAGDNY--GA 286
H I + NR+ C F + + R C P HGY G+N+ G+
Sbjct: 109 HYIL-----KGSNRSQCLEDHTWAPPFPI-CKSRDCDPPGNPVHGYFE----GNNFTLGS 158
Query: 287 TCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
T Y+C+ Y G + C +WS + P+C
Sbjct: 159 TISYYCEDRYYLVGVQEQQCVDG-EWSSALPVC 190
>gi|62912464 complement component 4 binding protein, beta chain
isoform 1 precursor [Homo sapiens]
Length = 252
Score = 58.2 bits (139), Expect = 2e-08
Identities = 28/95 (29%), Positives = 49/95 (51%), Gaps = 4/95 (4%)
Query: 91 CDRGFRLIGRRSVQCLPSRRWSGTAY-CRQMRCHALPFITSGTYTCTNGVLLDSRCDYSC 149
C +G+ L+G++++ C S+ W T CR C P + +G ++ + V + + + C
Sbjct: 49 CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPD-PVLVNGEFSSSGPVNVSDKITFMC 107
Query: 150 SSGYHLEGDRSRICMEDGRWSGGEPVCV--DIDPP 182
+ Y L+G C+ED W+ P+C D DPP
Sbjct: 108 NDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPP 142
Score = 42.4 bits (98), Expect = 0.001
Identities = 33/111 (29%), Positives = 44/111 (39%), Gaps = 4/111 (3%)
Query: 91 CDRGFRLIGRRSVQCLPSRRWSGT-AYCRQMRCHALPFITSGTYTCTNGVLLDSRCDYSC 149
C+ + L G QCL W+ C+ C G Y N L S Y C
Sbjct: 107 CNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHG-YFEGNNFTLGSTISYYC 165
Query: 150 SSGYHLEGDRSRICMEDGRWSGGEPVCVDI-DPPKIRCPHSREKMAEPEKL 199
Y+L G + + C+ DG WS PVC I + PK C + E + L
Sbjct: 166 EDRYYLVGVQEQQCV-DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNL 215
Score = 36.2 bits (82), Expect = 0.065
Identities = 50/213 (23%), Positives = 72/213 (33%), Gaps = 59/213 (27%)
Query: 122 CHALPFITSGTYTC--TNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDI 179
C LP + + + G +L + Y C GYHL G ++ C W C
Sbjct: 23 CPELPPVDNSIFVAKEVEGQILGT---YVCIKGYHLVGKKTLFCNASKEWDNTTTEC--- 76
Query: 180 DPPKIRCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSH---FPEGE 236
CP DP LV + GP S F +
Sbjct: 77 --RLGHCP------------------DPVLVNGEFSSS-------GPVNVSDKITFMCND 109
Query: 237 HVIRYTAYDRAYNRASC--------KFIVKVQVRRCPTLKPPQHGYLTCTSAGDNY--GA 286
H I + NR+ C F + + R C P HGY G+N+ G+
Sbjct: 110 HYIL-----KGSNRSQCLEDHTWAPPFPI-CKSRDCDPPGNPVHGYFE----GNNFTLGS 159
Query: 287 TCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
T Y+C+ Y G + C +WS + P+C
Sbjct: 160 TISYYCEDRYYLVGVQEQQCVDG-EWSSALPVC 191
>gi|62912462 complement component 4 binding protein, beta chain
isoform 2 precursor [Homo sapiens]
Length = 251
Score = 58.2 bits (139), Expect = 2e-08
Identities = 28/95 (29%), Positives = 49/95 (51%), Gaps = 4/95 (4%)
Query: 91 CDRGFRLIGRRSVQCLPSRRWSGTAY-CRQMRCHALPFITSGTYTCTNGVLLDSRCDYSC 149
C +G+ L+G++++ C S+ W T CR C P + +G ++ + V + + + C
Sbjct: 48 CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPD-PVLVNGEFSSSGPVNVSDKITFMC 106
Query: 150 SSGYHLEGDRSRICMEDGRWSGGEPVCV--DIDPP 182
+ Y L+G C+ED W+ P+C D DPP
Sbjct: 107 NDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPP 141
Score = 42.4 bits (98), Expect = 0.001
Identities = 33/111 (29%), Positives = 44/111 (39%), Gaps = 4/111 (3%)
Query: 91 CDRGFRLIGRRSVQCLPSRRWSGT-AYCRQMRCHALPFITSGTYTCTNGVLLDSRCDYSC 149
C+ + L G QCL W+ C+ C G Y N L S Y C
Sbjct: 106 CNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHG-YFEGNNFTLGSTISYYC 164
Query: 150 SSGYHLEGDRSRICMEDGRWSGGEPVCVDI-DPPKIRCPHSREKMAEPEKL 199
Y+L G + + C+ DG WS PVC I + PK C + E + L
Sbjct: 165 EDRYYLVGVQEQQCV-DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNL 214
Score = 36.2 bits (82), Expect = 0.065
Identities = 50/213 (23%), Positives = 72/213 (33%), Gaps = 59/213 (27%)
Query: 122 CHALPFITSGTYTC--TNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDI 179
C LP + + + G +L + Y C GYHL G ++ C W C
Sbjct: 22 CPELPPVDNSIFVAKEVEGQILGT---YVCIKGYHLVGKKTLFCNASKEWDNTTTEC--- 75
Query: 180 DPPKIRCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSH---FPEGE 236
CP DP LV + GP S F +
Sbjct: 76 --RLGHCP------------------DPVLVNGEFSSS-------GPVNVSDKITFMCND 108
Query: 237 HVIRYTAYDRAYNRASC--------KFIVKVQVRRCPTLKPPQHGYLTCTSAGDNY--GA 286
H I + NR+ C F + + R C P HGY G+N+ G+
Sbjct: 109 HYIL-----KGSNRSQCLEDHTWAPPFPI-CKSRDCDPPGNPVHGYFE----GNNFTLGS 158
Query: 287 TCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
T Y+C+ Y G + C +WS + P+C
Sbjct: 159 TISYYCEDRYYLVGVQEQQCVDG-EWSSALPVC 190
>gi|4502505 complement component 4 binding protein, beta chain
isoform 1 precursor [Homo sapiens]
Length = 252
Score = 58.2 bits (139), Expect = 2e-08
Identities = 28/95 (29%), Positives = 49/95 (51%), Gaps = 4/95 (4%)
Query: 91 CDRGFRLIGRRSVQCLPSRRWSGTAY-CRQMRCHALPFITSGTYTCTNGVLLDSRCDYSC 149
C +G+ L+G++++ C S+ W T CR C P + +G ++ + V + + + C
Sbjct: 49 CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPD-PVLVNGEFSSSGPVNVSDKITFMC 107
Query: 150 SSGYHLEGDRSRICMEDGRWSGGEPVCV--DIDPP 182
+ Y L+G C+ED W+ P+C D DPP
Sbjct: 108 NDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPP 142
Score = 42.4 bits (98), Expect = 0.001
Identities = 33/111 (29%), Positives = 44/111 (39%), Gaps = 4/111 (3%)
Query: 91 CDRGFRLIGRRSVQCLPSRRWSGT-AYCRQMRCHALPFITSGTYTCTNGVLLDSRCDYSC 149
C+ + L G QCL W+ C+ C G Y N L S Y C
Sbjct: 107 CNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHG-YFEGNNFTLGSTISYYC 165
Query: 150 SSGYHLEGDRSRICMEDGRWSGGEPVCVDI-DPPKIRCPHSREKMAEPEKL 199
Y+L G + + C+ DG WS PVC I + PK C + E + L
Sbjct: 166 EDRYYLVGVQEQQCV-DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNL 215
Score = 36.2 bits (82), Expect = 0.065
Identities = 50/213 (23%), Positives = 72/213 (33%), Gaps = 59/213 (27%)
Query: 122 CHALPFITSGTYTC--TNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDI 179
C LP + + + G +L + Y C GYHL G ++ C W C
Sbjct: 23 CPELPPVDNSIFVAKEVEGQILGT---YVCIKGYHLVGKKTLFCNASKEWDNTTTEC--- 76
Query: 180 DPPKIRCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSH---FPEGE 236
CP DP LV + GP S F +
Sbjct: 77 --RLGHCP------------------DPVLVNGEFSSS-------GPVNVSDKITFMCND 109
Query: 237 HVIRYTAYDRAYNRASC--------KFIVKVQVRRCPTLKPPQHGYLTCTSAGDNY--GA 286
H I + NR+ C F + + R C P HGY G+N+ G+
Sbjct: 110 HYIL-----KGSNRSQCLEDHTWAPPFPI-CKSRDCDPPGNPVHGYFE----GNNFTLGS 159
Query: 287 TCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
T Y+C+ Y G + C +WS + P+C
Sbjct: 160 TISYYCEDRYYLVGVQEQQCVDG-EWSSALPVC 191
>gi|86793109 complement receptor 1 isoform S precursor [Homo sapiens]
Length = 2489
Score = 57.8 bits (138), Expect = 2e-08
Identities = 70/260 (26%), Positives = 100/260 (38%), Gaps = 50/260 (19%)
Query: 83 LGTRCELSCDRGFRLIGRRSVQCLPS---RRWS-GTAYCRQMRCHALPFITSGTYTCTN- 137
+G+R SC G RLIG S +C+ S WS C+++ C P I +G + TN
Sbjct: 1473 VGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNR 1532
Query: 138 -GVLLDSRCDYSCSSG------YHLEGDRSRICMED----GRWSGGEPVCVDIDPPKIRC 186
S Y C+ G + L G+ S C + G WSG P C+
Sbjct: 1533 ENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCI--------- 1583
Query: 187 PHSREKMAEPEKLTARVYWDPPLVKDSAD-GTITRVTLRGPEPGSHFPEGEHVIRYTAYD 245
P K T + LV D+ ++ V +PG +G ++ A +
Sbjct: 1584 --------IPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPG-FVMKGPRRVKCQALN 1634
Query: 246 R-AYNRASCKFIVKVQVRRCPTLKPPQ--HGYLTCTSAGDNY--GATCEYHCDGGYDRQG 300
+ SC + + PP+ HG T S DN+ G Y C+ GYD +G
Sbjct: 1635 KWEPELPSCSRVCQ---------PPPEILHGEHT-PSHQDNFSPGQEVFYSCEPGYDLRG 1684
Query: 301 TPSRVCQSSRQWSGSPPICA 320
S C WS P CA
Sbjct: 1685 AASLHCTPQGDWSPEAPRCA 1704
Score = 55.5 bits (132), Expect = 1e-07
Identities = 66/257 (25%), Positives = 98/257 (38%), Gaps = 48/257 (18%)
Query: 84 GTRCELSCDRGFRLIGRRSVQCLPSRR---WSG-TAYCRQMRCHALPFITSGTYTCTN-- 137
G++ + SC +G+RLIG S C+ S W T C ++ C P IT+G + TN
Sbjct: 124 GSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRE 183
Query: 138 GVLLDSRCDYSCSSG------YHLEGDRSRICMED----GRWSGGEPVCVDIDPPKIRCP 187
S Y C+ G + L G+ S C + G WSG P C+
Sbjct: 184 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCII--------- 234
Query: 188 HSREKMAEPEKLTARVYWDPPLVKDSAD-GTITRVTLRGPEPGSHFPEGEHVIRYTAYDR 246
P K T + LV D+ ++ V +PG +G ++ A ++
Sbjct: 235 --------PNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPG-FVMKGPRRVKCQALNK 285
Query: 247 -AYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAG-DNY--GATCEYHCDGGYDRQGTP 302
SC + + PP + T DN+ G Y C+ GYD +G
Sbjct: 286 WEPELPSCSRVCQ---------PPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAA 336
Query: 303 SRVCQSSRQWSGSPPIC 319
S C WS + P C
Sbjct: 337 SMRCTPQGDWSPAAPTC 353
Score = 55.1 bits (131), Expect = 1e-07
Identities = 67/263 (25%), Positives = 94/263 (35%), Gaps = 48/263 (18%)
Query: 78 NYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRR---WSGTA-YCRQMRCHALPFITSGTY 133
N + G+ SC+ GFRLIG S CL S W A C + C P I++G +
Sbjct: 1921 NTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDF 1980
Query: 134 TCTNGVLLDSRC--DYSCSSG------YHLEGDRSRICMED----GRWSGGEPVCVDIDP 181
N + Y C +G + L G+RS C G WS P C+ +
Sbjct: 1981 YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTN- 2039
Query: 182 PKIRCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRY 241
K P + P R ++ T+T + +PG G H ++
Sbjct: 2040 -KCTAPEVENAIRVPGN---RSFF-----------TLTEIIRFRCQPG-FVMVGSHTVQC 2083
Query: 242 TAYDR-AYNRASCKFIVKVQVRRCPTLKPPQ--HGYLTCTSAGDNY--GATCEYHCDGGY 296
R C + + PP+ HG T S DN+ G Y C+ Y
Sbjct: 2084 QTNGRWGPKLPHCSRVCQ---------PPPEILHGEHTL-SHQDNFSPGQEVFYSCEPSY 2133
Query: 297 DRQGTPSRVCQSSRQWSGSPPIC 319
D +G S C WS P C
Sbjct: 2134 DLRGAASLHCTPQGDWSPEAPRC 2156
Score = 54.7 bits (130), Expect = 2e-07
Identities = 67/257 (26%), Positives = 95/257 (36%), Gaps = 46/257 (17%)
Query: 83 LGTRCELSCDRGFRLIGRRSVQCLPS---RRWS-GTAYCRQMRCHALPFITSGTYTCTN- 137
+G+R SC G RLIG S +C+ S WS C+++ C P I +G + TN
Sbjct: 573 VGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNR 632
Query: 138 -GVLLDSRCDYSCSSG------YHLEGDRSRICMED----GRWSGGEPVCVDIDPPKIRC 186
S Y C+ G + L G+ S C + G WSG P C+
Sbjct: 633 ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCI--------- 683
Query: 187 PHSREKMAEPEKLTARVYWDPPLVKDSAD-GTITRVTLRGPEPGSHFPEGEHVIRYTAYD 245
P K T + LV D+ ++ V +PG +G ++ A +
Sbjct: 684 --------IPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPG-FVMKGPRRVKCQALN 734
Query: 246 R-AYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNY--GATCEYHCDGGYDRQGTP 302
+ SC R C H T DN+ G Y C+ GYD +G
Sbjct: 735 KWEPELPSCS-------RVCQPPPDVLHAERTQRDK-DNFSPGQEVFYSCEPGYDLRGAA 786
Query: 303 SRVCQSSRQWSGSPPIC 319
S C WS + P C
Sbjct: 787 SMRCTPQGDWSPAAPTC 803
Score = 54.7 bits (130), Expect = 2e-07
Identities = 67/257 (26%), Positives = 95/257 (36%), Gaps = 46/257 (17%)
Query: 83 LGTRCELSCDRGFRLIGRRSVQCLPS---RRWS-GTAYCRQMRCHALPFITSGTYTCTN- 137
+G+R SC G RLIG S +C+ S WS C+++ C P I +G + TN
Sbjct: 1023 VGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNR 1082
Query: 138 -GVLLDSRCDYSCSSG------YHLEGDRSRICMED----GRWSGGEPVCVDIDPPKIRC 186
S Y C+ G + L G+ S C + G WSG P C+
Sbjct: 1083 ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCI--------- 1133
Query: 187 PHSREKMAEPEKLTARVYWDPPLVKDSAD-GTITRVTLRGPEPGSHFPEGEHVIRYTAYD 245
P K T + LV D+ ++ V +PG +G ++ A +
Sbjct: 1134 --------IPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPG-FVMKGPRRVKCQALN 1184
Query: 246 R-AYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNY--GATCEYHCDGGYDRQGTP 302
+ SC R C H T DN+ G Y C+ GYD +G
Sbjct: 1185 KWEPELPSCS-------RVCQPPPDVLHAERTQRDK-DNFSPGQEVFYSCEPGYDLRGAA 1236
Query: 303 SRVCQSSRQWSGSPPIC 319
S C WS + P C
Sbjct: 1237 SMRCTPQGDWSPAAPTC 1253
Score = 50.8 bits (120), Expect = 3e-06
Identities = 68/276 (24%), Positives = 95/276 (34%), Gaps = 37/276 (13%)
Query: 49 PALDYRVPRWCYTLNIQDGEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPS 108
PA +P C N+++G SL E C GF + G R V+C
Sbjct: 1578 PAPQCIIPNKCTPPNVENGILV----SDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQAL 1633
Query: 109 RRWSGTAYCRQMRCHALPFITSGTYTCTN--GVLLDSRCDYSCSSGYHLEGDRSRICMED 166
+W C P I G +T ++ YSC GY L G S C
Sbjct: 1634 NKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQ 1693
Query: 167 GRWSGGEPVCV--DIDPPKIRCPHSREKMAEPEKLTARVYW---DPPLVKDSADGTITRV 221
G WS P C D + PH R +L A+V + + +K S+ V
Sbjct: 1694 GDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLV 1753
Query: 222 TLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAG 281
+R S P EH+ CP +G T T +G
Sbjct: 1754 GMRSLWNNS-VPVCEHIF------------------------CPNPPAILNGRHTGTPSG 1788
Query: 282 D-NYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSP 316
D YG Y CD DR T + + +S+ + + P
Sbjct: 1789 DIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDP 1824
Score = 49.7 bits (117), Expect = 6e-06
Identities = 35/110 (31%), Positives = 47/110 (42%), Gaps = 10/110 (9%)
Query: 83 LGTRCELSCDRGFRLIGRR-SVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGVL 140
+GT C G+ GR S+ CL + W+G CR+ C P +G G+
Sbjct: 65 IGTYLNYECRPGYS--GRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQ 122
Query: 141 LDSRCDYSCSSGYHLEGDRSRICMEDGR---WSGGEPVCVDID---PPKI 184
S+ YSC+ GY L G S C+ G W P+C I PP I
Sbjct: 123 FGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTI 172
Score = 48.1 bits (113), Expect = 2e-05
Identities = 63/259 (24%), Positives = 98/259 (37%), Gaps = 50/259 (19%)
Query: 83 LGTRCELSCDRGFRLIGRRSVQCL---PSRRW-SGTAYCRQMRCHALPFITSGTYTCT-- 136
LG + CD GFRL GR + C+ W S C Q+ C P I +G +T T
Sbjct: 2181 LGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPF 2240
Query: 137 NGVLLDSRCDYSCSS------GYHLEGDRSRICMED----GRWSGGEPVCVDIDPPKIRC 186
+ Y+C + ++L G+ S C D G WS P C ++ P C
Sbjct: 2241 GDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRC-ELSVP-AAC 2298
Query: 187 PHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVI------R 240
PH P K+ Y + TI+ + +PG + G+ I
Sbjct: 2299 PH-------PPKIQNGHYIGGHVSLYLPGMTISYIC----DPG-YLLVGKGFIFCTDQGI 2346
Query: 241 YTAYDRAYNRASCKFIVKVQ-VRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQ 299
++ D +C F + + + + +K H YG C+ GY +
Sbjct: 2347 WSQLDHYCKEVNCSFPLFMNGISKELEMKKVYH-----------YGDYVTLKCEDGYTLE 2395
Query: 300 GTPSRVCQSSRQWSGSPPI 318
G+P CQ+ +W PP+
Sbjct: 2396 GSPWSQCQADDRW--DPPL 2412
Score = 46.6 bits (109), Expect = 5e-05
Identities = 35/118 (29%), Positives = 49/118 (41%), Gaps = 6/118 (5%)
Query: 91 CDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTN--GVLLDSRCDY 147
C GF ++G +VQC + RW +C ++ C P I G +T ++ Y
Sbjct: 2069 CQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV-CQPPPEILHGEHTLSHQDNFSPGQEVFY 2127
Query: 148 SCSSGYHLEGDRSRICMEDGRWSGGEPVCV--DIDPPKIRCPHSREKMAEPEKLTARV 203
SC Y L G S C G WS P C D + PH R + +L A+V
Sbjct: 2128 SCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKV 2185
Score = 45.8 bits (107), Expect = 8e-05
Identities = 41/145 (28%), Positives = 56/145 (38%), Gaps = 22/145 (15%)
Query: 48 APALDYRVPRWC-YTLNIQDGEATCYSPKGGNYHSSL-GTRCELSCDRGFRLIGRRSVQC 105
AP + VP C + IQ+G GG+ L G CD G+ L+G+ + C
Sbjct: 2287 APRCELSVPAACPHPPKIQNGHYI-----GGHVSLYLPGMTISYICDPGYLLVGKGFIFC 2341
Query: 106 LPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGVLLDSRCDY---SCSSGYHLEGDRSR 161
WS YC+++ C + P +G + DY C GY LEG
Sbjct: 2342 TDQGIWSQLDHYCKEVNC-SFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWS 2400
Query: 162 ICMEDGRWSGGEPVCVDIDPPKIRC 186
C D RW DPP +C
Sbjct: 2401 QCQADDRW----------DPPLAKC 2415
Score = 45.1 bits (105), Expect = 1e-04
Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 7/90 (7%)
Query: 102 SVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRS 160
S+ CL + WS C++ C P +G + + SR +YSC++G+ L G S
Sbjct: 533 SITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSS 592
Query: 161 RICMEDG---RWSGGEPVCVDID---PPKI 184
C+ G WS P+C I PP I
Sbjct: 593 AECILSGNAAHWSTKPPICQRIPCGLPPTI 622
Score = 45.1 bits (105), Expect = 1e-04
Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 7/90 (7%)
Query: 102 SVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRS 160
S+ CL + WS C++ C P +G + + SR +YSC++G+ L G S
Sbjct: 983 SITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSS 1042
Query: 161 RICMEDG---RWSGGEPVCVDID---PPKI 184
C+ G WS P+C I PP I
Sbjct: 1043 AECILSGNAAHWSTKPPICQRIPCGLPPTI 1072
Score = 45.1 bits (105), Expect = 1e-04
Identities = 30/112 (26%), Positives = 46/112 (41%), Gaps = 9/112 (8%)
Query: 78 NYHSSLGTRCELSCDRGFRLIGRR-SVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTC 135
++ +GT C G+ G+ S+ CL + WS CR+ C P +G
Sbjct: 1863 DFEFPVGTSLNYECRPGY--FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHI 1920
Query: 136 TNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGR---WSGGEPVC--VDIDPP 182
S +YSC+ G+ L G S C+ G W P+C + +PP
Sbjct: 1921 NTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPP 1972
Score = 44.7 bits (104), Expect = 2e-04
Identities = 34/130 (26%), Positives = 43/130 (33%), Gaps = 6/130 (4%)
Query: 49 PALDYRVPRWCYTLNIQDGEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPS 108
PA +P C N+++G SL E C GF + G R V+C
Sbjct: 228 PAPQCIIPNKCTPPNVENGILV----SDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQAL 283
Query: 109 RRWSGTAYCRQMRCHALPFITSG--TYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMED 166
+W C P + T + YSC GY L G S C
Sbjct: 284 NKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQ 343
Query: 167 GRWSGGEPVC 176
G WS P C
Sbjct: 344 GDWSPAAPTC 353
Score = 44.7 bits (104), Expect = 2e-04
Identities = 34/130 (26%), Positives = 43/130 (33%), Gaps = 6/130 (4%)
Query: 49 PALDYRVPRWCYTLNIQDGEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPS 108
PA +P C N+++G SL E C GF + G R V+C
Sbjct: 678 PAPQCIIPNKCTPPNVENGILV----SDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQAL 733
Query: 109 RRWSGTAYCRQMRCHALPFITSG--TYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMED 166
+W C P + T + YSC GY L G S C
Sbjct: 734 NKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQ 793
Query: 167 GRWSGGEPVC 176
G WS P C
Sbjct: 794 GDWSPAAPTC 803
Score = 44.7 bits (104), Expect = 2e-04
Identities = 34/130 (26%), Positives = 43/130 (33%), Gaps = 6/130 (4%)
Query: 49 PALDYRVPRWCYTLNIQDGEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPS 108
PA +P C N+++G SL E C GF + G R V+C
Sbjct: 1128 PAPQCIIPNKCTPPNVENGILV----SDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQAL 1183
Query: 109 RRWSGTAYCRQMRCHALPFITSG--TYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMED 166
+W C P + T + YSC GY L G S C
Sbjct: 1184 NKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQ 1243
Query: 167 GRWSGGEPVC 176
G WS P C
Sbjct: 1244 GDWSPAAPTC 1253
Score = 42.0 bits (97), Expect = 0.001
Identities = 63/250 (25%), Positives = 90/250 (36%), Gaps = 27/250 (10%)
Query: 82 SLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRC-HALPFITSGTYTCTNGV 139
S G SC+ + L G S+ C P WS A C C L + G +
Sbjct: 2120 SPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNL 2179
Query: 140 LLDSRCDYSCSSGYHLEGDRSRICMEDGR---WSGGEPVCVDIDPPKIRCPHSREKMAEP 196
L ++ + C G+ L+G + C+ G W+ PVC +I CP+ +
Sbjct: 2180 QLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVC-----EQIFCPNPPAIL--N 2232
Query: 197 EKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFP-EGEHVIRYTAYDRAYNRAS--- 252
+ T + D P K+ + T P+ G F GE IR T+ + S
Sbjct: 2233 GRHTGTPFGDIPYGKEISYACDTH-----PDRGMTFNLIGESSIRCTSDPQGNGVWSSPA 2287
Query: 253 --CKFIVKVQVRRCPTLKPPQHG-YLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSS 309
C+ V CP Q+G Y+ + G T Y CD GY G C
Sbjct: 2288 PRCELSVPA---ACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQ 2344
Query: 310 RQWSGSPPIC 319
WS C
Sbjct: 2345 GIWSQLDHYC 2354
Score = 41.6 bits (96), Expect = 0.002
Identities = 62/260 (23%), Positives = 90/260 (34%), Gaps = 46/260 (17%)
Query: 83 LGTRCELSCDRGFRLIGRRSVQCL---PSRRWSGTA-YCRQMRCHALPFITSGTYTCT-- 136
LG + CD GFRL G C+ W+ + C + C P I +G +T T
Sbjct: 1728 LGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPS 1787
Query: 137 ----NGVLLDSRCDYSCSSG--YHLEGDRSRICMED----GRWSGGEPVCVDIDPPKIRC 186
G + CD G ++L G+ + C D G WS P C +R
Sbjct: 1788 GDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRC----ELSVRA 1843
Query: 187 PHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEG--EHVIRYTAY 244
H + PE+ P + GT R G F E+++ +
Sbjct: 1844 GHCK----TPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVE 1899
Query: 245 DRAYNRASCKFIVKVQVRRCPTLKPPQHGY--LTCTSAGDNYGATCEYHCDGGYDRQGTP 302
D R SC PP + + + +G+T Y C+ G+ G+P
Sbjct: 1900 DNC-RRKSC--------------GPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSP 1944
Query: 303 SRVCQSSRQ---WSGSPPIC 319
S C S W PIC
Sbjct: 1945 STTCLVSGNNVTWDKKAPIC 1964
Score = 40.8 bits (94), Expect = 0.003
Identities = 77/322 (23%), Positives = 110/322 (34%), Gaps = 57/322 (17%)
Query: 83 LGTRCELSCDRGFRLIGRRSVQC----LPSRRWSGTAYCRQMRCHALPFITSGTYT---- 134
LG + + CD GF+L G + C + S S C Q+ C + P I +G +T
Sbjct: 1278 LGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPL 1337
Query: 135 --CTNGVLLDSRCDYSCSSG--YHLEGDRSRICMED----GRWSGGEPVCVDIDPPKIRC 186
G ++ CD G + L G+ + C D G WS P RC
Sbjct: 1338 EVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAP----------RC 1387
Query: 187 PHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDR 246
A L A++ D GT + R G F T D
Sbjct: 1388 GILGHCQAPDHFLFAKLKTQTN-ASDFPIGTSLKYECRPEYYGRPF-------SITCLDN 1439
Query: 247 AYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVC 306
+S K + K + C T P +G + G+ Y C G+ G S C
Sbjct: 1440 LV-WSSPKDVCK--RKSCKTPPDPVNG-MVHVITDIQVGSRINYSCTTGHRLIGHSSAEC 1495
Query: 307 ---QSSRQWSGSPPICAPMKINVNVNSAAGLLDQFYEKQRLLIISAPDPSNRYYKMQISM 363
++ WS PPIC + + A G F R N +Y ++
Sbjct: 1496 ILSGNTAHWSTKPPICQRIPCGLPPTIANG---DFISTNR---------ENFHYGSVVTY 1543
Query: 364 LQQSTCGLDLRHVTIIELVGQP 385
C L R + ELVG+P
Sbjct: 1544 ----RCNLGSRGRKVFELVGEP 1561
Score = 37.7 bits (86), Expect = 0.022
Identities = 63/256 (24%), Positives = 89/256 (34%), Gaps = 41/256 (16%)
Query: 83 LGTRCELSCDRGFRLIGRRSVQC----LPSRRWSGTAYCRQMRCHALPFITSGTYT---- 134
LG + + CD GF+L G + C + S S C Q+ C + P I +G +T
Sbjct: 378 LGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPL 437
Query: 135 --CTNGVLLDSRCDYSCSSG--YHLEGDRSRICMED----GRWSGGEPVCVDIDPPKIRC 186
G ++ CD G + L G+ + C D G WS P RC
Sbjct: 438 EVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAP----------RC 487
Query: 187 PHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDR 246
A L A++ D GT + R G F T D
Sbjct: 488 GILGHCQAPDHFLFAKLKTQTN-ASDFPIGTSLKYECRPEYYGRPF-------SITCLDN 539
Query: 247 AYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVC 306
+S K + K + C T P +G + G+ Y C G+ G S C
Sbjct: 540 LV-WSSPKDVCK--RKSCKTPPDPVNG-MVHVITDIQVGSRINYSCTTGHRLIGHSSAEC 595
Query: 307 ---QSSRQWSGSPPIC 319
++ WS PPIC
Sbjct: 596 ILSGNAAHWSTKPPIC 611
Score = 37.7 bits (86), Expect = 0.022
Identities = 63/256 (24%), Positives = 89/256 (34%), Gaps = 41/256 (16%)
Query: 83 LGTRCELSCDRGFRLIGRRSVQC----LPSRRWSGTAYCRQMRCHALPFITSGTYT---- 134
LG + + CD GF+L G + C + S S C Q+ C + P I +G +T
Sbjct: 828 LGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPL 887
Query: 135 --CTNGVLLDSRCDYSCSSG--YHLEGDRSRICMED----GRWSGGEPVCVDIDPPKIRC 186
G ++ CD G + L G+ + C D G WS P RC
Sbjct: 888 EVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAP----------RC 937
Query: 187 PHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDR 246
A L A++ D GT + R G F T D
Sbjct: 938 GILGHCQAPDHFLFAKLKTQTN-ASDFPIGTSLKYECRPEYYGRPF-------SITCLDN 989
Query: 247 AYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVC 306
+S K + K + C T P +G + G+ Y C G+ G S C
Sbjct: 990 LV-WSSPKDVCK--RKSCKTPPDPVNG-MVHVITDIQVGSRINYSCTTGHRLIGHSSAEC 1045
Query: 307 ---QSSRQWSGSPPIC 319
++ WS PPIC
Sbjct: 1046 ILSGNAAHWSTKPPIC 1061
Score = 37.4 bits (85), Expect = 0.029
Identities = 30/114 (26%), Positives = 43/114 (37%), Gaps = 12/114 (10%)
Query: 79 YHSSLGTRCELSCDRG--FRLIGRRSVQCLPSRRWSGTAYCRQMRCHAL--------PFI 128
Y + C+ DRG F LIG S++C + +G RC P I
Sbjct: 2245 YGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKI 2304
Query: 129 TSGTYTCTNGVLL--DSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDID 180
+G Y + L Y C GY L G C + G WS + C +++
Sbjct: 2305 QNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEVN 2358
Score = 34.7 bits (78), Expect = 0.19
Identities = 53/270 (19%), Positives = 93/270 (34%), Gaps = 39/270 (14%)
Query: 64 IQDGEATCYSPKGGNYHSSLGTRCELSCD--RGFRLIGRRSVQCLPSRR----WSGTA-Y 116
I +G+ + + +Y S + RC + F L+G S+ C + WSG A
Sbjct: 172 ITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQ 231
Query: 117 CRQMRCHALPFITSGTYTCTNGVL--LDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEP 174
C P + +G N L L+ ++ C G+ ++G R C +W P
Sbjct: 232 CIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELP 291
Query: 175 VCVDIDPPKIRCPHSREKMAEPEKLT--ARVYWDPPLVKDSADGTITRVTLRGPEPGSHF 232
C + P H+ + + + V++ D LRG
Sbjct: 292 SCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYD----------LRGAASMRCT 341
Query: 233 PEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHC 292
P+G D + +C +V+ C GA ++ C
Sbjct: 342 PQG---------DWSPAAPTC------EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVC 386
Query: 293 DGGYDRQGTPSRVCQSSRQ---WSGSPPIC 319
D G+ +G+ + C + W+ S P+C
Sbjct: 387 DEGFQLKGSSASYCVLAGMESLWNSSVPVC 416
Score = 34.7 bits (78), Expect = 0.19
Identities = 53/270 (19%), Positives = 93/270 (34%), Gaps = 39/270 (14%)
Query: 64 IQDGEATCYSPKGGNYHSSLGTRCELSCD--RGFRLIGRRSVQCLPSRR----WSGTA-Y 116
I +G+ + + +Y S + RC + F L+G S+ C + WSG A
Sbjct: 622 IANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQ 681
Query: 117 CRQMRCHALPFITSGTYTCTNGVL--LDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEP 174
C P + +G N L L+ ++ C G+ ++G R C +W P
Sbjct: 682 CIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELP 741
Query: 175 VCVDIDPPKIRCPHSREKMAEPEKLT--ARVYWDPPLVKDSADGTITRVTLRGPEPGSHF 232
C + P H+ + + + V++ D LRG
Sbjct: 742 SCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYD----------LRGAASMRCT 791
Query: 233 PEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHC 292
P+G D + +C +V+ C GA ++ C
Sbjct: 792 PQG---------DWSPAAPTC------EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVC 836
Query: 293 DGGYDRQGTPSRVCQSSRQ---WSGSPPIC 319
D G+ +G+ + C + W+ S P+C
Sbjct: 837 DEGFQLKGSSASYCVLAGMESLWNSSVPVC 866
Score = 34.7 bits (78), Expect = 0.19
Identities = 53/270 (19%), Positives = 93/270 (34%), Gaps = 39/270 (14%)
Query: 64 IQDGEATCYSPKGGNYHSSLGTRCELSCD--RGFRLIGRRSVQCLPSRR----WSGTA-Y 116
I +G+ + + +Y S + RC + F L+G S+ C + WSG A
Sbjct: 1072 IANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQ 1131
Query: 117 CRQMRCHALPFITSGTYTCTNGVL--LDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEP 174
C P + +G N L L+ ++ C G+ ++G R C +W P
Sbjct: 1132 CIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELP 1191
Query: 175 VCVDIDPPKIRCPHSREKMAEPEKLT--ARVYWDPPLVKDSADGTITRVTLRGPEPGSHF 232
C + P H+ + + + V++ D LRG
Sbjct: 1192 SCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYD----------LRGAASMRCT 1241
Query: 233 PEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHC 292
P+G D + +C +V+ C GA ++ C
Sbjct: 1242 PQG---------DWSPAAPTC------EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVC 1286
Query: 293 DGGYDRQGTPSRVCQSSRQ---WSGSPPIC 319
D G+ +G+ + C + W+ S P+C
Sbjct: 1287 DEGFQLKGSSASYCVLAGMESLWNSSVPVC 1316
Score = 31.6 bits (70), Expect = 1.6
Identities = 30/142 (21%), Positives = 47/142 (33%), Gaps = 15/142 (10%)
Query: 72 YSPKGGNYHSSLGTRCELSCDRG------FRLIGRRSVQCLPSRRWSGTAYCRQMRCHAL 125
YS ++H+ GT C G F L+G RS+ C G RC +
Sbjct: 1981 YSNNRTSFHN--GTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCIST 2038
Query: 126 PFITSGTYTCTNGV-------LLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVD 178
T+ V L + C G+ + G + C +GRW P C
Sbjct: 2039 NKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSR 2098
Query: 179 IDPPKIRCPHSREKMAEPEKLT 200
+ P H ++ + +
Sbjct: 2099 VCQPPPEILHGEHTLSHQDNFS 2120
>gi|86793036 complement receptor 1 isoform F precursor [Homo sapiens]
Length = 2039
Score = 57.8 bits (138), Expect = 2e-08
Identities = 70/260 (26%), Positives = 100/260 (38%), Gaps = 50/260 (19%)
Query: 83 LGTRCELSCDRGFRLIGRRSVQCLPS---RRWS-GTAYCRQMRCHALPFITSGTYTCTN- 137
+G+R SC G RLIG S +C+ S WS C+++ C P I +G + TN
Sbjct: 1023 VGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNR 1082
Query: 138 -GVLLDSRCDYSCSSG------YHLEGDRSRICMED----GRWSGGEPVCVDIDPPKIRC 186
S Y C+ G + L G+ S C + G WSG P C+
Sbjct: 1083 ENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCI--------- 1133
Query: 187 PHSREKMAEPEKLTARVYWDPPLVKDSAD-GTITRVTLRGPEPGSHFPEGEHVIRYTAYD 245
P K T + LV D+ ++ V +PG +G ++ A +
Sbjct: 1134 --------IPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPG-FVMKGPRRVKCQALN 1184
Query: 246 R-AYNRASCKFIVKVQVRRCPTLKPPQ--HGYLTCTSAGDNY--GATCEYHCDGGYDRQG 300
+ SC + + PP+ HG T S DN+ G Y C+ GYD +G
Sbjct: 1185 KWEPELPSCSRVCQ---------PPPEILHGEHT-PSHQDNFSPGQEVFYSCEPGYDLRG 1234
Query: 301 TPSRVCQSSRQWSGSPPICA 320
S C WS P CA
Sbjct: 1235 AASLHCTPQGDWSPEAPRCA 1254
Score = 55.5 bits (132), Expect = 1e-07
Identities = 66/257 (25%), Positives = 98/257 (38%), Gaps = 48/257 (18%)
Query: 84 GTRCELSCDRGFRLIGRRSVQCLPSRR---WSG-TAYCRQMRCHALPFITSGTYTCTN-- 137
G++ + SC +G+RLIG S C+ S W T C ++ C P IT+G + TN
Sbjct: 124 GSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRE 183
Query: 138 GVLLDSRCDYSCSSG------YHLEGDRSRICMED----GRWSGGEPVCVDIDPPKIRCP 187
S Y C+ G + L G+ S C + G WSG P C+
Sbjct: 184 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCII--------- 234
Query: 188 HSREKMAEPEKLTARVYWDPPLVKDSAD-GTITRVTLRGPEPGSHFPEGEHVIRYTAYDR 246
P K T + LV D+ ++ V +PG +G ++ A ++
Sbjct: 235 --------PNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPG-FVMKGPRRVKCQALNK 285
Query: 247 -AYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAG-DNY--GATCEYHCDGGYDRQGTP 302
SC + + PP + T DN+ G Y C+ GYD +G
Sbjct: 286 WEPELPSCSRVCQ---------PPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAA 336
Query: 303 SRVCQSSRQWSGSPPIC 319
S C WS + P C
Sbjct: 337 SMRCTPQGDWSPAAPTC 353
Score = 55.1 bits (131), Expect = 1e-07
Identities = 67/263 (25%), Positives = 94/263 (35%), Gaps = 48/263 (18%)
Query: 78 NYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRR---WSGTA-YCRQMRCHALPFITSGTY 133
N + G+ SC+ GFRLIG S CL S W A C + C P I++G +
Sbjct: 1471 NTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDF 1530
Query: 134 TCTNGVLLDSRC--DYSCSSG------YHLEGDRSRICMED----GRWSGGEPVCVDIDP 181
N + Y C +G + L G+RS C G WS P C+ +
Sbjct: 1531 YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTN- 1589
Query: 182 PKIRCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRY 241
K P + P R ++ T+T + +PG G H ++
Sbjct: 1590 -KCTAPEVENAIRVPGN---RSFF-----------TLTEIIRFRCQPG-FVMVGSHTVQC 1633
Query: 242 TAYDR-AYNRASCKFIVKVQVRRCPTLKPPQ--HGYLTCTSAGDNY--GATCEYHCDGGY 296
R C + + PP+ HG T S DN+ G Y C+ Y
Sbjct: 1634 QTNGRWGPKLPHCSRVCQ---------PPPEILHGEHTL-SHQDNFSPGQEVFYSCEPSY 1683
Query: 297 DRQGTPSRVCQSSRQWSGSPPIC 319
D +G S C WS P C
Sbjct: 1684 DLRGAASLHCTPQGDWSPEAPRC 1706
Score = 54.7 bits (130), Expect = 2e-07
Identities = 67/257 (26%), Positives = 95/257 (36%), Gaps = 46/257 (17%)
Query: 83 LGTRCELSCDRGFRLIGRRSVQCLPS---RRWS-GTAYCRQMRCHALPFITSGTYTCTN- 137
+G+R SC G RLIG S +C+ S WS C+++ C P I +G + TN
Sbjct: 573 VGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNR 632
Query: 138 -GVLLDSRCDYSCSSG------YHLEGDRSRICMED----GRWSGGEPVCVDIDPPKIRC 186
S Y C+ G + L G+ S C + G WSG P C+
Sbjct: 633 ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCI--------- 683
Query: 187 PHSREKMAEPEKLTARVYWDPPLVKDSAD-GTITRVTLRGPEPGSHFPEGEHVIRYTAYD 245
P K T + LV D+ ++ V +PG +G ++ A +
Sbjct: 684 --------IPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPG-FVMKGPRRVKCQALN 734
Query: 246 R-AYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNY--GATCEYHCDGGYDRQGTP 302
+ SC R C H T DN+ G Y C+ GYD +G
Sbjct: 735 KWEPELPSCS-------RVCQPPPDVLHAERTQRDK-DNFSPGQEVFYSCEPGYDLRGAA 786
Query: 303 SRVCQSSRQWSGSPPIC 319
S C WS + P C
Sbjct: 787 SMRCTPQGDWSPAAPTC 803
Score = 50.8 bits (120), Expect = 3e-06
Identities = 68/276 (24%), Positives = 95/276 (34%), Gaps = 37/276 (13%)
Query: 49 PALDYRVPRWCYTLNIQDGEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPS 108
PA +P C N+++G SL E C GF + G R V+C
Sbjct: 1128 PAPQCIIPNKCTPPNVENGILV----SDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQAL 1183
Query: 109 RRWSGTAYCRQMRCHALPFITSGTYTCTN--GVLLDSRCDYSCSSGYHLEGDRSRICMED 166
+W C P I G +T ++ YSC GY L G S C
Sbjct: 1184 NKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQ 1243
Query: 167 GRWSGGEPVCV--DIDPPKIRCPHSREKMAEPEKLTARVYW---DPPLVKDSADGTITRV 221
G WS P C D + PH R +L A+V + + +K S+ V
Sbjct: 1244 GDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLV 1303
Query: 222 TLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAG 281
+R S P EH+ CP +G T T +G
Sbjct: 1304 GMRSLWNNS-VPVCEHIF------------------------CPNPPAILNGRHTGTPSG 1338
Query: 282 D-NYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSP 316
D YG Y CD DR T + + +S+ + + P
Sbjct: 1339 DIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDP 1374
Score = 49.7 bits (117), Expect = 6e-06
Identities = 35/110 (31%), Positives = 47/110 (42%), Gaps = 10/110 (9%)
Query: 83 LGTRCELSCDRGFRLIGRR-SVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGVL 140
+GT C G+ GR S+ CL + W+G CR+ C P +G G+
Sbjct: 65 IGTYLNYECRPGYS--GRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQ 122
Query: 141 LDSRCDYSCSSGYHLEGDRSRICMEDGR---WSGGEPVCVDID---PPKI 184
S+ YSC+ GY L G S C+ G W P+C I PP I
Sbjct: 123 FGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTI 172
Score = 48.1 bits (113), Expect = 2e-05
Identities = 63/259 (24%), Positives = 98/259 (37%), Gaps = 50/259 (19%)
Query: 83 LGTRCELSCDRGFRLIGRRSVQCL---PSRRW-SGTAYCRQMRCHALPFITSGTYTCT-- 136
LG + CD GFRL GR + C+ W S C Q+ C P I +G +T T
Sbjct: 1731 LGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPF 1790
Query: 137 NGVLLDSRCDYSCSS------GYHLEGDRSRICMED----GRWSGGEPVCVDIDPPKIRC 186
+ Y+C + ++L G+ S C D G WS P C ++ P C
Sbjct: 1791 GDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRC-ELSVP-AAC 1848
Query: 187 PHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVI------R 240
PH P K+ Y + TI+ + +PG + G+ I
Sbjct: 1849 PH-------PPKIQNGHYIGGHVSLYLPGMTISYIC----DPG-YLLVGKGFIFCTDQGI 1896
Query: 241 YTAYDRAYNRASCKFIVKVQ-VRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQ 299
++ D +C F + + + + +K H YG C+ GY +
Sbjct: 1897 WSQLDHYCKEVNCSFPLFMNGISKELEMKKVYH-----------YGDYVTLKCEDGYTLE 1945
Query: 300 GTPSRVCQSSRQWSGSPPI 318
G+P CQ+ +W PP+
Sbjct: 1946 GSPWSQCQADDRW--DPPL 1962
Score = 46.6 bits (109), Expect = 5e-05
Identities = 35/118 (29%), Positives = 49/118 (41%), Gaps = 6/118 (5%)
Query: 91 CDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTN--GVLLDSRCDY 147
C GF ++G +VQC + RW +C ++ C P I G +T ++ Y
Sbjct: 1619 CQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV-CQPPPEILHGEHTLSHQDNFSPGQEVFY 1677
Query: 148 SCSSGYHLEGDRSRICMEDGRWSGGEPVCV--DIDPPKIRCPHSREKMAEPEKLTARV 203
SC Y L G S C G WS P C D + PH R + +L A+V
Sbjct: 1678 SCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKV 1735
Score = 45.8 bits (107), Expect = 8e-05
Identities = 41/145 (28%), Positives = 56/145 (38%), Gaps = 22/145 (15%)
Query: 48 APALDYRVPRWC-YTLNIQDGEATCYSPKGGNYHSSL-GTRCELSCDRGFRLIGRRSVQC 105
AP + VP C + IQ+G GG+ L G CD G+ L+G+ + C
Sbjct: 1837 APRCELSVPAACPHPPKIQNGHYI-----GGHVSLYLPGMTISYICDPGYLLVGKGFIFC 1891
Query: 106 LPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGVLLDSRCDY---SCSSGYHLEGDRSR 161
WS YC+++ C + P +G + DY C GY LEG
Sbjct: 1892 TDQGIWSQLDHYCKEVNC-SFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWS 1950
Query: 162 ICMEDGRWSGGEPVCVDIDPPKIRC 186
C D RW DPP +C
Sbjct: 1951 QCQADDRW----------DPPLAKC 1965
Score = 45.1 bits (105), Expect = 1e-04
Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 7/90 (7%)
Query: 102 SVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRS 160
S+ CL + WS C++ C P +G + + SR +YSC++G+ L G S
Sbjct: 533 SITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSS 592
Query: 161 RICMEDG---RWSGGEPVCVDID---PPKI 184
C+ G WS P+C I PP I
Sbjct: 593 AECILSGNAAHWSTKPPICQRIPCGLPPTI 622
Score = 45.1 bits (105), Expect = 1e-04
Identities = 30/112 (26%), Positives = 46/112 (41%), Gaps = 9/112 (8%)
Query: 78 NYHSSLGTRCELSCDRGFRLIGRR-SVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTC 135
++ +GT C G+ G+ S+ CL + WS CR+ C P +G
Sbjct: 1413 DFEFPVGTSLNYECRPGY--FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHI 1470
Query: 136 TNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGR---WSGGEPVC--VDIDPP 182
S +YSC+ G+ L G S C+ G W P+C + +PP
Sbjct: 1471 NTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPP 1522
Score = 44.7 bits (104), Expect = 2e-04
Identities = 34/130 (26%), Positives = 43/130 (33%), Gaps = 6/130 (4%)
Query: 49 PALDYRVPRWCYTLNIQDGEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPS 108
PA +P C N+++G SL E C GF + G R V+C
Sbjct: 228 PAPQCIIPNKCTPPNVENGILV----SDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQAL 283
Query: 109 RRWSGTAYCRQMRCHALPFITSG--TYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMED 166
+W C P + T + YSC GY L G S C
Sbjct: 284 NKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQ 343
Query: 167 GRWSGGEPVC 176
G WS P C
Sbjct: 344 GDWSPAAPTC 353
Score = 44.7 bits (104), Expect = 2e-04
Identities = 34/130 (26%), Positives = 43/130 (33%), Gaps = 6/130 (4%)
Query: 49 PALDYRVPRWCYTLNIQDGEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPS 108
PA +P C N+++G SL E C GF + G R V+C
Sbjct: 678 PAPQCIIPNKCTPPNVENGILV----SDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQAL 733
Query: 109 RRWSGTAYCRQMRCHALPFITSG--TYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMED 166
+W C P + T + YSC GY L G S C
Sbjct: 734 NKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQ 793
Query: 167 GRWSGGEPVC 176
G WS P C
Sbjct: 794 GDWSPAAPTC 803
Score = 42.0 bits (97), Expect = 0.001
Identities = 63/250 (25%), Positives = 90/250 (36%), Gaps = 27/250 (10%)
Query: 82 SLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRC-HALPFITSGTYTCTNGV 139
S G SC+ + L G S+ C P WS A C C L + G +
Sbjct: 1670 SPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNL 1729
Query: 140 LLDSRCDYSCSSGYHLEGDRSRICMEDGR---WSGGEPVCVDIDPPKIRCPHSREKMAEP 196
L ++ + C G+ L+G + C+ G W+ PVC +I CP+ +
Sbjct: 1730 QLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVC-----EQIFCPNPPAIL--N 1782
Query: 197 EKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFP-EGEHVIRYTAYDRAYNRAS--- 252
+ T + D P K+ + T P+ G F GE IR T+ + S
Sbjct: 1783 GRHTGTPFGDIPYGKEISYACDTH-----PDRGMTFNLIGESSIRCTSDPQGNGVWSSPA 1837
Query: 253 --CKFIVKVQVRRCPTLKPPQHG-YLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSS 309
C+ V CP Q+G Y+ + G T Y CD GY G C
Sbjct: 1838 PRCELSVPA---ACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQ 1894
Query: 310 RQWSGSPPIC 319
WS C
Sbjct: 1895 GIWSQLDHYC 1904
Score = 41.6 bits (96), Expect = 0.002
Identities = 62/260 (23%), Positives = 90/260 (34%), Gaps = 46/260 (17%)
Query: 83 LGTRCELSCDRGFRLIGRRSVQCL---PSRRWSGTA-YCRQMRCHALPFITSGTYTCT-- 136
LG + CD GFRL G C+ W+ + C + C P I +G +T T
Sbjct: 1278 LGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPS 1337
Query: 137 ----NGVLLDSRCDYSCSSG--YHLEGDRSRICMED----GRWSGGEPVCVDIDPPKIRC 186
G + CD G ++L G+ + C D G WS P C +R
Sbjct: 1338 GDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRC----ELSVRA 1393
Query: 187 PHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEG--EHVIRYTAY 244
H + PE+ P + GT R G F E+++ +
Sbjct: 1394 GHCK----TPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVE 1449
Query: 245 DRAYNRASCKFIVKVQVRRCPTLKPPQHGY--LTCTSAGDNYGATCEYHCDGGYDRQGTP 302
D R SC PP + + + +G+T Y C+ G+ G+P
Sbjct: 1450 DNC-RRKSC--------------GPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSP 1494
Query: 303 SRVCQSSRQ---WSGSPPIC 319
S C S W PIC
Sbjct: 1495 STTCLVSGNNVTWDKKAPIC 1514
Score = 40.8 bits (94), Expect = 0.003
Identities = 77/322 (23%), Positives = 110/322 (34%), Gaps = 57/322 (17%)
Query: 83 LGTRCELSCDRGFRLIGRRSVQC----LPSRRWSGTAYCRQMRCHALPFITSGTYT---- 134
LG + + CD GF+L G + C + S S C Q+ C + P I +G +T
Sbjct: 828 LGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPL 887
Query: 135 --CTNGVLLDSRCDYSCSSG--YHLEGDRSRICMED----GRWSGGEPVCVDIDPPKIRC 186
G ++ CD G + L G+ + C D G WS P RC
Sbjct: 888 EVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAP----------RC 937
Query: 187 PHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDR 246
A L A++ D GT + R G F T D
Sbjct: 938 GILGHCQAPDHFLFAKLKTQTN-ASDFPIGTSLKYECRPEYYGRPF-------SITCLDN 989
Query: 247 AYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVC 306
+S K + K + C T P +G + G+ Y C G+ G S C
Sbjct: 990 LV-WSSPKDVCK--RKSCKTPPDPVNG-MVHVITDIQVGSRINYSCTTGHRLIGHSSAEC 1045
Query: 307 ---QSSRQWSGSPPICAPMKINVNVNSAAGLLDQFYEKQRLLIISAPDPSNRYYKMQISM 363
++ WS PPIC + + A G F R N +Y ++
Sbjct: 1046 ILSGNTAHWSTKPPICQRIPCGLPPTIANG---DFISTNR---------ENFHYGSVVTY 1093
Query: 364 LQQSTCGLDLRHVTIIELVGQP 385
C L R + ELVG+P
Sbjct: 1094 ----RCNLGSRGRKVFELVGEP 1111
Score = 37.7 bits (86), Expect = 0.022
Identities = 63/256 (24%), Positives = 89/256 (34%), Gaps = 41/256 (16%)
Query: 83 LGTRCELSCDRGFRLIGRRSVQC----LPSRRWSGTAYCRQMRCHALPFITSGTYT---- 134
LG + + CD GF+L G + C + S S C Q+ C + P I +G +T
Sbjct: 378 LGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPL 437
Query: 135 --CTNGVLLDSRCDYSCSSG--YHLEGDRSRICMED----GRWSGGEPVCVDIDPPKIRC 186
G ++ CD G + L G+ + C D G WS P RC
Sbjct: 438 EVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAP----------RC 487
Query: 187 PHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDR 246
A L A++ D GT + R G F T D
Sbjct: 488 GILGHCQAPDHFLFAKLKTQTN-ASDFPIGTSLKYECRPEYYGRPF-------SITCLDN 539
Query: 247 AYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVC 306
+S K + K + C T P +G + G+ Y C G+ G S C
Sbjct: 540 LV-WSSPKDVCK--RKSCKTPPDPVNG-MVHVITDIQVGSRINYSCTTGHRLIGHSSAEC 595
Query: 307 ---QSSRQWSGSPPIC 319
++ WS PPIC
Sbjct: 596 ILSGNAAHWSTKPPIC 611
Score = 37.4 bits (85), Expect = 0.029
Identities = 30/114 (26%), Positives = 43/114 (37%), Gaps = 12/114 (10%)
Query: 79 YHSSLGTRCELSCDRG--FRLIGRRSVQCLPSRRWSGTAYCRQMRCHAL--------PFI 128
Y + C+ DRG F LIG S++C + +G RC P I
Sbjct: 1795 YGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKI 1854
Query: 129 TSGTYTCTNGVLL--DSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDID 180
+G Y + L Y C GY L G C + G WS + C +++
Sbjct: 1855 QNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEVN 1908
Score = 34.7 bits (78), Expect = 0.19
Identities = 53/270 (19%), Positives = 93/270 (34%), Gaps = 39/270 (14%)
Query: 64 IQDGEATCYSPKGGNYHSSLGTRCELSCD--RGFRLIGRRSVQCLPSRR----WSGTA-Y 116
I +G+ + + +Y S + RC + F L+G S+ C + WSG A
Sbjct: 172 ITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQ 231
Query: 117 CRQMRCHALPFITSGTYTCTNGVL--LDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEP 174
C P + +G N L L+ ++ C G+ ++G R C +W P
Sbjct: 232 CIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELP 291
Query: 175 VCVDIDPPKIRCPHSREKMAEPEKLT--ARVYWDPPLVKDSADGTITRVTLRGPEPGSHF 232
C + P H+ + + + V++ D LRG
Sbjct: 292 SCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYD----------LRGAASMRCT 341
Query: 233 PEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHC 292
P+G D + +C +V+ C GA ++ C
Sbjct: 342 PQG---------DWSPAAPTC------EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVC 386
Query: 293 DGGYDRQGTPSRVCQSSRQ---WSGSPPIC 319
D G+ +G+ + C + W+ S P+C
Sbjct: 387 DEGFQLKGSSASYCVLAGMESLWNSSVPVC 416
Score = 34.7 bits (78), Expect = 0.19
Identities = 53/270 (19%), Positives = 93/270 (34%), Gaps = 39/270 (14%)
Query: 64 IQDGEATCYSPKGGNYHSSLGTRCELSCD--RGFRLIGRRSVQCLPSRR----WSGTA-Y 116
I +G+ + + +Y S + RC + F L+G S+ C + WSG A
Sbjct: 622 IANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQ 681
Query: 117 CRQMRCHALPFITSGTYTCTNGVL--LDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEP 174
C P + +G N L L+ ++ C G+ ++G R C +W P
Sbjct: 682 CIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELP 741
Query: 175 VCVDIDPPKIRCPHSREKMAEPEKLT--ARVYWDPPLVKDSADGTITRVTLRGPEPGSHF 232
C + P H+ + + + V++ D LRG
Sbjct: 742 SCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYD----------LRGAASMRCT 791
Query: 233 PEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHC 292
P+G D + +C +V+ C GA ++ C
Sbjct: 792 PQG---------DWSPAAPTC------EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVC 836
Query: 293 DGGYDRQGTPSRVCQSSRQ---WSGSPPIC 319
D G+ +G+ + C + W+ S P+C
Sbjct: 837 DEGFQLKGSSASYCVLAGMESLWNSSVPVC 866
Score = 31.6 bits (70), Expect = 1.6
Identities = 30/142 (21%), Positives = 47/142 (33%), Gaps = 15/142 (10%)
Query: 72 YSPKGGNYHSSLGTRCELSCDRG------FRLIGRRSVQCLPSRRWSGTAYCRQMRCHAL 125
YS ++H+ GT C G F L+G RS+ C G RC +
Sbjct: 1531 YSNNRTSFHN--GTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCIST 1588
Query: 126 PFITSGTYTCTNGV-------LLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVD 178
T+ V L + C G+ + G + C +GRW P C
Sbjct: 1589 NKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSR 1648
Query: 179 IDPPKIRCPHSREKMAEPEKLT 200
+ P H ++ + +
Sbjct: 1649 VCQPPPEILHGEHTLSHQDNFS 1670
>gi|67782358 complement factor B preproprotein [Homo sapiens]
Length = 764
Score = 57.0 bits (136), Expect = 4e-08
Identities = 40/118 (33%), Positives = 52/118 (44%), Gaps = 7/118 (5%)
Query: 63 NIQDGEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSG-TAYCRQMR 121
+ ++GE Y P+ Y+ S C G+ L G + C + RWSG TA C
Sbjct: 108 DFENGE---YWPRSPYYNVS--DEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGA 162
Query: 122 CHAL-PFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVD 178
+ P I GT + L+ Y CS G L G + R C E G WSG EP C D
Sbjct: 163 GYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQD 220
Score = 39.7 bits (91), Expect = 0.006
Identities = 41/189 (21%), Positives = 58/189 (30%), Gaps = 44/189 (23%)
Query: 146 DYSCSSGYHLEGDRSRICMEDGRWSG----GEPVCVDIDPPKIRCPHSREKMAEPEKLTA 201
+Y C SG++ ++R C G WS + + I CP P
Sbjct: 59 EYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPR-------PHDFEN 111
Query: 202 RVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQV 261
YW P S + I + YD R S +V
Sbjct: 112 GEYW----------------------PRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNG 149
Query: 262 RRCPTLKPPQHGYLTCTSAGDNYGA-----------TCEYHCDGGYDRQGTPSRVCQSSR 310
R +G C++ G G + YHC G +G+ R CQ
Sbjct: 150 RWSGQTAICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGG 209
Query: 311 QWSGSPPIC 319
WSG+ P C
Sbjct: 210 SWSGTEPSC 218
>gi|14550407 complement component 2 isoform 1 preproprotein [Homo
sapiens]
Length = 752
Score = 55.8 bits (133), Expect = 8e-08
Identities = 37/107 (34%), Positives = 47/107 (43%), Gaps = 4/107 (3%)
Query: 72 YSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSG-TAYCRQMRCHAL-PFIT 129
Y+P+ G+Y +G C+ GF L G QC P+ W G TA C H P I+
Sbjct: 100 YTPRLGSY--PVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGIS 157
Query: 130 SGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVC 176
G + Y CSS L G R C +G WSG EP+C
Sbjct: 158 LGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPIC 204
Score = 40.8 bits (94), Expect = 0.003
Identities = 22/94 (23%), Positives = 38/94 (40%), Gaps = 6/94 (6%)
Query: 226 PEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYG 285
P P S + + R+ ++A CK + RCP ++G T G
Sbjct: 57 PSPASRLCKSSGQWQTPGATRSLSKAVCKPV------RCPAPVSFENGIYTPRLGSYPVG 110
Query: 286 ATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
+ C+ G+ +G+P R C+ + W G +C
Sbjct: 111 GNVSFECEDGFILRGSPVRQCRPNGMWDGETAVC 144
Score = 38.9 bits (89), Expect = 0.010
Identities = 49/204 (24%), Positives = 65/204 (31%), Gaps = 41/204 (20%)
Query: 128 ITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRW-------SGGEPVCVDID 180
I+ GT+T ++G S YSC G + SR+C G+W S + VC
Sbjct: 30 ISGGTFTLSHGWAPGSLLTYSCPQGLY-PSPASRLCKSSGQWQTPGATRSLSKAVC---- 84
Query: 181 PPKIRCPHSREKMAEPEKLTARVYWDPPLVKDSADGTIT-----RVTLRGPEPGSHFPEG 235
+RCP P +Y P L G ++ LRG P G
Sbjct: 85 -KPVRCP-------APVSFENGIY-TPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNG 135
Query: 236 EHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGG 295
D I VR T +G Y C
Sbjct: 136 MWDGETAVCDNGAGHCPNPGISLGAVR---------------TGFRFGHGDKVRYRCSSN 180
Query: 296 YDRQGTPSRVCQSSRQWSGSPPIC 319
G+ R CQ + WSG+ PIC
Sbjct: 181 LVLTGSSERECQGNGVWSGTEPIC 204
>gi|153266841 apolipoprotein H precursor [Homo sapiens]
Length = 345
Score = 54.7 bits (130), Expect = 2e-07
Identities = 62/249 (24%), Positives = 87/249 (34%), Gaps = 30/249 (12%)
Query: 84 GTRCELSCDRGF-RLIGRRSVQCLPSRRWS-GTAYCRQMRCHALPFITSGTYTCTNGVLL 141
G SC G+ G R C + W T C C + +G T
Sbjct: 44 GEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTT-FEY 102
Query: 142 DSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDI--DPPKIRCPHSREKMAEPEKL 199
+ +SC++G++L G S C E+G+WS PVC I PP I P
Sbjct: 103 PNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSI-----------PTFA 151
Query: 200 TARVYWDPPLVKDSA-DGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVK 258
T RVY K SA + ++ R T H G I T + C+ +
Sbjct: 152 TLRVY------KPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLPECREV-- 203
Query: 259 VQVRRCPTLKPPQHGYLTCTSAGD-NYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPP 317
+CP P +G++ + Y + C GY G C WS P
Sbjct: 204 ----KCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAMPS 259
Query: 318 ICAPMKINV 326
A K+ V
Sbjct: 260 CKASCKVPV 268
>gi|148922949 complement component (3b/4b) receptor 1-like [Homo
sapiens]
Length = 569
Score = 53.9 bits (128), Expect = 3e-07
Identities = 34/112 (30%), Positives = 51/112 (45%), Gaps = 10/112 (8%)
Query: 83 LGTRCELSCDRGFRLIGRRSVQCLPSRR---W-SGTAYCRQMRCHALPFITSGTYTCTNG 138
LG + + CD GF+L G + C+ + W S C + C P +G
Sbjct: 370 LGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITD 429
Query: 139 VLLDSRCDYSCSSGYHLEGDRSRICMEDG---RWSGGEPVCVDI---DPPKI 184
+ + SR +YSC++G+ L G S C+ G WS P+C I +PP I
Sbjct: 430 IHVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSMKPPICQQIFCPNPPAI 481
Score = 43.5 bits (101), Expect = 4e-04
Identities = 30/104 (28%), Positives = 42/104 (40%), Gaps = 7/104 (6%)
Query: 78 NYHSSLGTRCELSCDRGFRLIGRR-SVQCLPSRRW-SGTAYCRQMRCHALPFITSGTYTC 135
++ +GT C G+ GR S+ CL + W S C++ C P +G
Sbjct: 52 DFEFPIGTYLNYECRPGYS--GRPFSIICLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHV 109
Query: 136 TNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGR---WSGGEPVC 176
+ S+ YSC GY L G S C+ G W PVC
Sbjct: 110 IKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVC 153
Score = 39.7 bits (91), Expect = 0.006
Identities = 32/130 (24%), Positives = 41/130 (31%), Gaps = 6/130 (4%)
Query: 49 PALDYRVPRWCYTLNIQDGEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPS 108
PA +P C N+++G SL E C GF + G V+C
Sbjct: 220 PAPQCIIPNKCTPPNVENGILV----SDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQAL 275
Query: 109 RRWSGTAYCRQMRCHALPFITSG--TYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMED 166
+W C P + T + YSC GY L G C
Sbjct: 276 NKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQ 335
Query: 167 GRWSGGEPVC 176
G WS P C
Sbjct: 336 GDWSPAAPRC 345
Score = 35.4 bits (80), Expect = 0.11
Identities = 49/253 (19%), Positives = 88/253 (34%), Gaps = 41/253 (16%)
Query: 79 YHSSLGTRCELSCDRGFRLIGRRSVQCLPSRR----WSGTA-YCRQMRCHALPFITSGTY 133
YH +LG+R + + F L+G S+ C WSG A C P + +G
Sbjct: 185 YHCNLGSRGK----KVFELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCTPPNVENGIL 240
Query: 134 TCTNGVL--LDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSRE 191
N L L+ ++ C G+ ++G C +W P C + P H+
Sbjct: 241 VSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSRVCQPPPDVLHAER 300
Query: 192 KMAEPEKLT--ARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYN 249
+ + + V++ D T T P+G+ ++
Sbjct: 301 TQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCT----------PQGD-----------WS 339
Query: 250 RASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSS 309
A+ + +V+ C GA ++ CD G+ +G+ + C +
Sbjct: 340 PAA----PRCEVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLA 395
Query: 310 RQ---WSGSPPIC 319
W+ S P+C
Sbjct: 396 GMESLWNSSVPVC 408
>gi|168693643 decay accelerating factor for complement isoform 2
precursor [Homo sapiens]
Length = 440
Score = 51.6 bits (122), Expect = 1e-06
Identities = 34/111 (30%), Positives = 52/111 (46%), Gaps = 9/111 (8%)
Query: 83 LGTRCELSCDRGFRLIGRRS--VQCLPSRRWS-GTAYCRQMRCHALPFITSGTYTCTNGV 139
+GT E C G+R S + CL + +WS +C++ C I +G G+
Sbjct: 121 VGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGI 180
Query: 140 LLDSRCDYSCSSGYHLEGDRSRICMEDG---RWSGGEPVCVDI---DPPKI 184
L + +SC++GY L G S C+ G +WS P C +I PP+I
Sbjct: 181 LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQI 231
Score = 47.4 bits (111), Expect = 3e-05
Identities = 33/108 (30%), Positives = 48/108 (44%), Gaps = 22/108 (20%)
Query: 84 GTRCELSCDRGFRLIGRRSVQCL---PSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGV 139
G SC+ G++L G S CL S +WS CR++ C A P I NG+
Sbjct: 183 GATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQID-------NGI 235
Query: 140 LLDSR--------CDYSCSSGYHLEGDRSRICM---EDGRWSGGEPVC 176
+ R Y+C+ G+ + G+ S C ++G WSG P C
Sbjct: 236 IQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 32.7 bits (73), Expect = 0.72
Identities = 43/184 (23%), Positives = 69/184 (37%), Gaps = 27/184 (14%)
Query: 142 DSRCDYSCSSGY-HLEGDR-SRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKL 199
D+ Y C + + G++ S IC++ +WS E C P +L
Sbjct: 58 DTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFC-------------NRSCEVPTRL 104
Query: 200 TARVYWDPPLVKDSAD-GTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVK 258
+ P + ++ GT+ R PG + E + T + +F K
Sbjct: 105 NSASLKQPYITQNYFPVGTVVEYECR---PG-YRREPSLSPKLTCLQNLKWSTAVEFCKK 160
Query: 259 VQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVC---QSSRQWSGS 315
+ CP ++G + G +GAT + C+ GY G+ S C SS QWS
Sbjct: 161 ---KSCPNPGEIRNGQID-VPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDP 216
Query: 316 PPIC 319
P C
Sbjct: 217 LPEC 220
Score = 31.6 bits (70), Expect = 1.6
Identities = 54/242 (22%), Positives = 81/242 (33%), Gaps = 36/242 (14%)
Query: 91 CDRGF-RLIGRR-SVQCLPSRRWSGTAYCRQMRCHALPFITSGT----YTCTNGVLLDSR 144
C+ F ++ G + SV CL +WS C + S + Y N + +
Sbjct: 65 CEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTV 124
Query: 145 CDYSCSSGYHLEGDRSR--ICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTAR 202
+Y C GY E S C+++ +WS C K CP+ E +
Sbjct: 125 VEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFC-----KKKSCPNPGEIRNGQIDVPGG 179
Query: 203 VYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVR 262
+ + + G L G G V + C+ I
Sbjct: 180 ILFGATISFSCNTG----YKLFGSTSSFCLISGSSV------QWSDPLPECREIY----- 224
Query: 263 RCPTLKPPQHGYLTCTSAGDNYG--ATCEYHCDGGYDRQGTPSRVCQSSR---QWSGSPP 317
CP PPQ D+YG + Y C+ G+ G S C + +WSG PP
Sbjct: 225 -CPA--PPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPP 281
Query: 318 IC 319
C
Sbjct: 282 EC 283
>gi|10835143 decay accelerating factor for complement isoform 1
preproprotein [Homo sapiens]
Length = 381
Score = 51.6 bits (122), Expect = 1e-06
Identities = 34/111 (30%), Positives = 52/111 (46%), Gaps = 9/111 (8%)
Query: 83 LGTRCELSCDRGFRLIGRRS--VQCLPSRRWS-GTAYCRQMRCHALPFITSGTYTCTNGV 139
+GT E C G+R S + CL + +WS +C++ C I +G G+
Sbjct: 121 VGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGI 180
Query: 140 LLDSRCDYSCSSGYHLEGDRSRICMEDG---RWSGGEPVCVDI---DPPKI 184
L + +SC++GY L G S C+ G +WS P C +I PP+I
Sbjct: 181 LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQI 231
Score = 47.4 bits (111), Expect = 3e-05
Identities = 33/108 (30%), Positives = 48/108 (44%), Gaps = 22/108 (20%)
Query: 84 GTRCELSCDRGFRLIGRRSVQCL---PSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGV 139
G SC+ G++L G S CL S +WS CR++ C A P I NG+
Sbjct: 183 GATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQID-------NGI 235
Query: 140 LLDSR--------CDYSCSSGYHLEGDRSRICM---EDGRWSGGEPVC 176
+ R Y+C+ G+ + G+ S C ++G WSG P C
Sbjct: 236 IQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 32.7 bits (73), Expect = 0.72
Identities = 43/184 (23%), Positives = 69/184 (37%), Gaps = 27/184 (14%)
Query: 142 DSRCDYSCSSGY-HLEGDR-SRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKL 199
D+ Y C + + G++ S IC++ +WS E C P +L
Sbjct: 58 DTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFC-------------NRSCEVPTRL 104
Query: 200 TARVYWDPPLVKDSAD-GTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVK 258
+ P + ++ GT+ R PG + E + T + +F K
Sbjct: 105 NSASLKQPYITQNYFPVGTVVEYECR---PG-YRREPSLSPKLTCLQNLKWSTAVEFCKK 160
Query: 259 VQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVC---QSSRQWSGS 315
+ CP ++G + G +GAT + C+ GY G+ S C SS QWS
Sbjct: 161 ---KSCPNPGEIRNGQID-VPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDP 216
Query: 316 PPIC 319
P C
Sbjct: 217 LPEC 220
Score = 31.6 bits (70), Expect = 1.6
Identities = 54/242 (22%), Positives = 81/242 (33%), Gaps = 36/242 (14%)
Query: 91 CDRGF-RLIGRR-SVQCLPSRRWSGTAYCRQMRCHALPFITSGT----YTCTNGVLLDSR 144
C+ F ++ G + SV CL +WS C + S + Y N + +
Sbjct: 65 CEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTV 124
Query: 145 CDYSCSSGYHLEGDRSR--ICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTAR 202
+Y C GY E S C+++ +WS C K CP+ E +
Sbjct: 125 VEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFC-----KKKSCPNPGEIRNGQIDVPGG 179
Query: 203 VYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVR 262
+ + + G L G G V + C+ I
Sbjct: 180 ILFGATISFSCNTG----YKLFGSTSSFCLISGSSV------QWSDPLPECREIY----- 224
Query: 263 RCPTLKPPQHGYLTCTSAGDNYG--ATCEYHCDGGYDRQGTPSRVCQSSR---QWSGSPP 317
CP PPQ D+YG + Y C+ G+ G S C + +WSG PP
Sbjct: 225 -CPA--PPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPP 281
Query: 318 IC 319
C
Sbjct: 282 EC 283
>gi|27502421 CD46 antigen, complement regulatory protein isoform 13
precursor [Homo sapiens]
Length = 373
Score = 51.2 bits (121), Expect = 2e-06
Identities = 63/262 (24%), Positives = 102/262 (38%), Gaps = 33/262 (12%)
Query: 83 LGTRCELSCDRGFRLIGRRSVQCLPSRR--WSGTA--YCRQMRCHALPFITSGTYTCTNG 138
+G R + C +G+ I + + R W + C + C + +G NG
Sbjct: 56 IGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANG 115
Query: 139 VL-LDSRCDYSCSSGYHLEGDRSRICMEDGR---WSGGEPVCVDI---DPPKIRC-PHSR 190
+ + C+ GY+L G+ C G WSG P+C + PPKI+ H+
Sbjct: 116 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 175
Query: 191 EKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNR 250
++ E L A Y P GP+P S GE I Y + ++R
Sbjct: 176 SEVEVFEYLDAVTYSCDPAP--------------GPDPFSLI--GESTI-YCGDNSVWSR 218
Query: 251 ASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSR 310
A+ + KV R P ++ + ++ Y AT + CD G+ G+ + VC S+
Sbjct: 219 AAPE--CKVVKCRFPVVENGKQ--ISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNS 274
Query: 311 QWSGSPPICAPMKINVNVNSAA 332
W P C + + S A
Sbjct: 275 TWDPPVPKCLKVSTSSTTKSPA 296
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,827,221
Number of Sequences: 37866
Number of extensions: 1066638
Number of successful extensions: 3161
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 35
Number of HSP's that attempted gapping in prelim test: 2113
Number of HSP's gapped (non-prelim): 776
length of query: 465
length of database: 18,247,518
effective HSP length: 106
effective length of query: 359
effective length of database: 14,233,722
effective search space: 5109906198
effective search space used: 5109906198
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.