Search of human proteins with 7657100

Search of human proteins with 7657100

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7657100 solute carrier family 40 (iron-regulated
transporter), member 1 [Homo sapiens]
         (571 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7657100 solute carrier family 40 (iron-regulated transporter)...  1132   0.0  
gi|32490567 relaxin 3 receptor 2 [Homo sapiens]                        35   0.19 
gi|153945765 mitogen-activated protein kinase kinase kinase 1 [H...    33   0.54 
gi|31415870 dedicator of cytokinesis 3 [Homo sapiens]                  33   0.92 
gi|87159824 CD151 antigen [Homo sapiens]                               32   1.2  
gi|87159822 CD151 antigen [Homo sapiens]                               32   1.2  
gi|21237751 CD151 antigen [Homo sapiens]                               32   1.2  
gi|21237748 CD151 antigen [Homo sapiens]                               32   1.2  
gi|4504659 interleukin 1 receptor, type I precursor [Homo sapiens]     32   1.6  
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        31   3.5  
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    31   3.5  
gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens]      31   3.5  
gi|12232395 lipid phosphate phosphatase-related protein type 2 [...    30   4.6  
gi|157041233 solute carrier family 16 (monocarboxylic acid trans...    30   4.6  
gi|5921992 adenosine A2a receptor [Homo sapiens]                       30   6.0  
gi|5031751 hydroxymethylglutaryl-CoA synthase 2 [Homo sapiens]         30   6.0  
gi|30023826 G-protein coupled purinergic receptor P2Y8 [Homo sap...    30   6.0  
gi|189491628 enamelin [Homo sapiens]                                   30   7.8  

>gi|7657100 solute carrier family 40 (iron-regulated transporter),
           member 1 [Homo sapiens]
          Length = 571

 Score = 1132 bits (2929), Expect = 0.0
 Identities = 571/571 (100%), Positives = 571/571 (100%)

Query: 1   MTRAGDHNRQRGCCGSLADYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLL 60
           MTRAGDHNRQRGCCGSLADYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLL
Sbjct: 1   MTRAGDHNRQRGCCGSLADYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLL 60

Query: 61  TAVYGLVVAGSVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKHEL 120
           TAVYGLVVAGSVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKHEL
Sbjct: 61  TAVYGLVVAGSVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKHEL 120

Query: 121 LTMYHGWVLTSCYILIITIANIANLASTATAITIQRDWIVVVAGEDRSKLANMNATIRRI 180
           LTMYHGWVLTSCYILIITIANIANLASTATAITIQRDWIVVVAGEDRSKLANMNATIRRI
Sbjct: 121 LTMYHGWVLTSCYILIITIANIANLASTATAITIQRDWIVVVAGEDRSKLANMNATIRRI 180

Query: 181 DQLTNILAPMAVGQIMTFGSPVIGCGFISGWNLVSMCVEYVLLWKVYQKTPALAVKAGLK 240
           DQLTNILAPMAVGQIMTFGSPVIGCGFISGWNLVSMCVEYVLLWKVYQKTPALAVKAGLK
Sbjct: 181 DQLTNILAPMAVGQIMTFGSPVIGCGFISGWNLVSMCVEYVLLWKVYQKTPALAVKAGLK 240

Query: 241 EEETELKQLNLHKDTEPKPLEGTHLMGVKDSNIHELEHEQEPTCASQMAEPFRTFRDGWV 300
           EEETELKQLNLHKDTEPKPLEGTHLMGVKDSNIHELEHEQEPTCASQMAEPFRTFRDGWV
Sbjct: 241 EEETELKQLNLHKDTEPKPLEGTHLMGVKDSNIHELEHEQEPTCASQMAEPFRTFRDGWV 300

Query: 301 SYYNQPVFLAGMGLAFLYMTVLGFDCITTGYAYTQGLSGSILSILMGASAITGIMGTVAF 360
           SYYNQPVFLAGMGLAFLYMTVLGFDCITTGYAYTQGLSGSILSILMGASAITGIMGTVAF
Sbjct: 301 SYYNQPVFLAGMGLAFLYMTVLGFDCITTGYAYTQGLSGSILSILMGASAITGIMGTVAF 360

Query: 361 TWLRRKCGLVRTGLISGLAQLSCLILCVISVFMPGSPLDLSVSPFEDIRSRFIQGESITP 420
           TWLRRKCGLVRTGLISGLAQLSCLILCVISVFMPGSPLDLSVSPFEDIRSRFIQGESITP
Sbjct: 361 TWLRRKCGLVRTGLISGLAQLSCLILCVISVFMPGSPLDLSVSPFEDIRSRFIQGESITP 420

Query: 421 TKIPEITTEIYMSNGSNSANIVPETSPESVPIISVSLLFAGVIAARIGLWSFDLTVTQLL 480
           TKIPEITTEIYMSNGSNSANIVPETSPESVPIISVSLLFAGVIAARIGLWSFDLTVTQLL
Sbjct: 421 TKIPEITTEIYMSNGSNSANIVPETSPESVPIISVSLLFAGVIAARIGLWSFDLTVTQLL 480

Query: 481 QENVIESERGIINGVQNSMNYLLDLLHFIMVILAPNPEAFGLLVLISVSFVAMGHIMYFR 540
           QENVIESERGIINGVQNSMNYLLDLLHFIMVILAPNPEAFGLLVLISVSFVAMGHIMYFR
Sbjct: 481 QENVIESERGIINGVQNSMNYLLDLLHFIMVILAPNPEAFGLLVLISVSFVAMGHIMYFR 540

Query: 541 FAQNTLGNKLFACGPDAKEVRKENQANTSVV 571
           FAQNTLGNKLFACGPDAKEVRKENQANTSVV
Sbjct: 541 FAQNTLGNKLFACGPDAKEVRKENQANTSVV 571


>gi|32490567 relaxin 3 receptor 2 [Homo sapiens]
          Length = 374

 Score = 35.0 bits (79), Expect = 0.19
 Identities = 37/150 (24%), Positives = 64/150 (42%), Gaps = 12/150 (8%)

Query: 58  LLLTAVYGLVVAGSVLVLGAIIGDWVDKNA--RLKVAQTSLVVQNVSVILCGIILMMVFL 115
           L++   YGLV  G++ +LG +   WV  N   R     +   V N+++   G+ L + F 
Sbjct: 40  LMVALAYGLV--GAIGLLGNLAVLWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFW 97

Query: 116 HKHELLTMYHGWVLTSC-YILIITIANIANLASTATAITIQRDWIVVVAGEDRSKLANMN 174
                L  +  +    C  +L  T+ N+       TA+++ R W+V +A    + L+   
Sbjct: 98  AAESALDFHWPFGGALCKMVLTATVLNVYASIFLITALSVARYWVVAMAAGPGTHLSLFW 157

Query: 175 ATIRRIDQLTNILAPMAVGQIMTFGSPVIG 204
           A I         LA  A   ++T  + V G
Sbjct: 158 ARIA-------TLAVWAAAALVTVPTAVFG 180


>gi|153945765 mitogen-activated protein kinase kinase kinase 1 [Homo
           sapiens]
          Length = 1512

 Score = 33.5 bits (75), Expect = 0.54
 Identities = 17/57 (29%), Positives = 27/57 (47%)

Query: 162 VAGEDRSKLANMNATIRRIDQLTNILAPMAVGQIMTFGSPVIGCGFISGWNLVSMCV 218
           +AG  R++ +N N T     Q+      +A   I  FG  ++GC F   WN+  M +
Sbjct: 528 LAGSRRNQESNFNLTHYGTQQIPPAYKDLAEPWIQVFGMELVGCLFSRNWNVREMAL 584


>gi|31415870 dedicator of cytokinesis 3 [Homo sapiens]
          Length = 2030

 Score = 32.7 bits (73), Expect = 0.92
 Identities = 24/66 (36%), Positives = 34/66 (51%), Gaps = 4/66 (6%)

Query: 499 MNYLLDLLHFIMVILAPNPEAFGLLVLISVSFV--AMGHIMYFRF--AQNTLGNKLFACG 554
           + +L D+L  + VIL  N E +GLLV  S+ F+   +  I YF F    +T   K FA  
Sbjct: 638 VKFLQDILDTLFVILDDNTEKYGLLVFQSLVFIINLLRDIKYFHFRPVMDTYIQKHFAGA 697

Query: 555 PDAKEV 560
              KE+
Sbjct: 698 LAYKEL 703


>gi|87159824 CD151 antigen [Homo sapiens]
          Length = 253

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 19/77 (24%), Positives = 36/77 (46%), Gaps = 1/77 (1%)

Query: 5  GDHNRQRGCCGSLA-DYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLLTAV 63
          G+ N ++  CG++   YL       +    L+     +W  A+    + L  +   L   
Sbjct: 2  GEFNEKKTTCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATA 61

Query: 64 YGLVVAGSVLVLGAIIG 80
          Y LVVAG+V+++  ++G
Sbjct: 62 YILVVAGTVVMVTGVLG 78


>gi|87159822 CD151 antigen [Homo sapiens]
          Length = 253

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 19/77 (24%), Positives = 36/77 (46%), Gaps = 1/77 (1%)

Query: 5  GDHNRQRGCCGSLA-DYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLLTAV 63
          G+ N ++  CG++   YL       +    L+     +W  A+    + L  +   L   
Sbjct: 2  GEFNEKKTTCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATA 61

Query: 64 YGLVVAGSVLVLGAIIG 80
          Y LVVAG+V+++  ++G
Sbjct: 62 YILVVAGTVVMVTGVLG 78


>gi|21237751 CD151 antigen [Homo sapiens]
          Length = 253

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 19/77 (24%), Positives = 36/77 (46%), Gaps = 1/77 (1%)

Query: 5  GDHNRQRGCCGSLA-DYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLLTAV 63
          G+ N ++  CG++   YL       +    L+     +W  A+    + L  +   L   
Sbjct: 2  GEFNEKKTTCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATA 61

Query: 64 YGLVVAGSVLVLGAIIG 80
          Y LVVAG+V+++  ++G
Sbjct: 62 YILVVAGTVVMVTGVLG 78


>gi|21237748 CD151 antigen [Homo sapiens]
          Length = 253

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 19/77 (24%), Positives = 36/77 (46%), Gaps = 1/77 (1%)

Query: 5  GDHNRQRGCCGSLA-DYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLLTAV 63
          G+ N ++  CG++   YL       +    L+     +W  A+    + L  +   L   
Sbjct: 2  GEFNEKKTTCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATA 61

Query: 64 YGLVVAGSVLVLGAIIG 80
          Y LVVAG+V+++  ++G
Sbjct: 62 YILVVAGTVVMVTGVLG 78


>gi|4504659 interleukin 1 receptor, type I precursor [Homo sapiens]
          Length = 569

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 5/49 (10%)

Query: 240 KEEETELKQLNLHKDTEPKPLEGTHLMGVKD----SNIHELEHEQEPTC 284
           K E  EL +L  +KD +P  L+  H  GVKD     N+ E +H    TC
Sbjct: 149 KNENNELPKLQWYKDCKPLLLDNIHFSGVKDRLIVMNVAE-KHRGNYTC 196


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 19/54 (35%), Positives = 24/54 (44%), Gaps = 1/54 (1%)

Query: 230  TPALAVKAGLKEEETELKQLNLHKDTEPKPLEGTHLMGVKDSNIHELEHEQEPT 283
            TPA +  AGL+EE T  +      DT P P  GT    V+ S  +       PT
Sbjct: 1567 TPASSTSAGLQEESTTFQSWPSSSDTTPSP-PGTTAAPVEVSTTYHSRPSSTPT 1619



 Score = 30.8 bits (68), Expect = 3.5
 Identities = 19/54 (35%), Positives = 24/54 (44%), Gaps = 1/54 (1%)

Query: 230  TPALAVKAGLKEEETELKQLNLHKDTEPKPLEGTHLMGVKDSNIHELEHEQEPT 283
            TPA +  AGL+EE T  +      DT P P  GT    V+ S  +       PT
Sbjct: 3124 TPASSTSAGLQEESTTFQSWPSSSDTTPSP-PGTTAAPVEVSTTYHSRPSSTPT 3176


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 19/54 (35%), Positives = 24/54 (44%), Gaps = 1/54 (1%)

Query: 230  TPALAVKAGLKEEETELKQLNLHKDTEPKPLEGTHLMGVKDSNIHELEHEQEPT 283
            TPA +  AGL+EE T  +      DT P P  GT    V+ S  +       PT
Sbjct: 1054 TPASSTSAGLQEESTTFQSWPSSSDTTPSP-PGTTAAPVEVSTTYHSRPSSTPT 1106


>gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens]
          Length = 4490

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 24/91 (26%), Positives = 46/91 (50%), Gaps = 6/91 (6%)

Query: 205  CGFISGWNLVSMCVEYVLLWKVYQK--TPALAVKAGLKEEETELKQLNLHKDTEPKPLEG 262
            CGF+     V +  ++ +L+K+ ++  T  +    GL+   + L+ L   K   P+  E 
Sbjct: 1988 CGFLEN---VILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSEL 2044

Query: 263  THLM-GVKDSNIHELEHEQEPTCASQMAEPF 292
            + +M G++D N+ +L  E EP   S + + F
Sbjct: 2045 SIVMRGLRDMNLSKLVDEDEPLFLSLINDLF 2075


>gi|12232395 lipid phosphate phosphatase-related protein type 2
           [Homo sapiens]
          Length = 343

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 16/55 (29%), Positives = 26/55 (47%)

Query: 354 IMGTVAFTWLRRKCGLVRTGLISGLAQLSCLILCVISVFMPGSPLDLSVSPFEDI 408
           ++G V     R     V  G ++G A  + L+ CV+  F    P    +SP+ED+
Sbjct: 250 LVGVVRVAEYRNHWSDVLAGFLTGAAIATFLVTCVVHNFQSRPPSGRRLSPWEDL 304


>gi|157041233 solute carrier family 16 (monocarboxylic acid
           transporters), member 12 [Homo sapiens]
          Length = 486

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 32/109 (29%), Positives = 47/109 (43%), Gaps = 5/109 (4%)

Query: 331 YAYTQGLSGSILSILMGASAITGIMGTVAFTWLRRKCGLVRTGLISGLAQLSCLILCVIS 390
           YA + G+S    + LM    +  I+G + F WL  +  L     +  L  +    LC + 
Sbjct: 277 YALSVGVSHQQAAFLMSILGVIDIIGNITFGWLTDRRCLKNYQYVCYLFAVGMDGLCYLC 336

Query: 391 VFMPGSPLDLSVSPFEDIRSRFIQGESITPTKIPEITTEIYMSNGSNSA 439
           + M  S L L V PF      F   +    T IP +TTEI  +   +SA
Sbjct: 337 LPMLQS-LPLLV-PFSCTFGYF---DGAYVTLIPVVTTEIVGTTSLSSA 380


>gi|5921992 adenosine A2a receptor [Homo sapiens]
          Length = 412

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 24/101 (23%), Positives = 50/101 (49%), Gaps = 8/101 (7%)

Query: 53  LYGNSLLLT---AVYGLVVAGSVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGII 109
           + G+S+ +T   A+  L + G+VLV  A+   W++ N +  V    +V    + I  G++
Sbjct: 3   IMGSSVYITVELAIAVLAILGNVLVCWAV---WLNSNLQ-NVTNYFVVSLAAADIAVGVL 58

Query: 110 LM-MVFLHKHELLTMYHGWVLTSCYILIITIANIANLASTA 149
            +              HG +  +C++L++T ++I +L + A
Sbjct: 59  AIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIA 99


>gi|5031751 hydroxymethylglutaryl-CoA synthase 2 [Homo sapiens]
          Length = 508

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 31/100 (31%), Positives = 42/100 (42%), Gaps = 12/100 (12%)

Query: 330 GYAYTQGLSGSILSILMGASAITGIMGTVAFTWLRRKCGLVRTGLISGLAQLSCLILCVI 389
           G  YT  L G + S+L   SA   + G+        + G    G  SGLA  S     V 
Sbjct: 379 GNMYTSSLYGCLASLLSHHSA-QELAGS--------RIGAFSYG--SGLAA-SFFSFRVS 426

Query: 390 SVFMPGSPLDLSVSPFEDIRSRFIQGESITPTKIPEITTE 429
               PGSPLD  VS   D+  R    + ++P +  EI  +
Sbjct: 427 QDAAPGSPLDKLVSSTSDLPKRLASRKCVSPEEFTEIMNQ 466


>gi|30023826 G-protein coupled purinergic receptor P2Y8 [Homo
           sapiens]
          Length = 359

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 13/106 (12%)

Query: 57  SLLLTAVYGLVVAGSVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSV---ILCGIILMMV 113
           ++ L  VY LV A  V + G +   WV        + + + + N+SV   +L  ++   +
Sbjct: 23  AVALPVVYSLVAA--VSIPGNLFSLWVLCRRMGPRSPSVIFMINLSVTDLMLASVLPFQI 80

Query: 114 FLHKHELLTMYHGWVLTSCYILIITIANIANLAS---TATAITIQR 156
           + H +      H WV       ++T+A  AN+ S   T T I+++R
Sbjct: 81  YYHCNR-----HHWVFGVLLCNVVTVAFYANMYSSILTMTCISVER 121


>gi|189491628 enamelin [Homo sapiens]
          Length = 1142

 Score = 29.6 bits (65), Expect = 7.8
 Identities = 16/49 (32%), Positives = 22/49 (44%)

Query: 403  SPFEDIRSRFIQGESITPTKIPEITTEIYMSNGSNSANIVPETSPESVP 451
            +P  D R     G+SITPT+ P    E+       S N+ P  + E  P
Sbjct: 1072 TPSSDGRQSPFDGDSITPTENPNTLVELATEEQFKSINVDPLDADEHSP 1120


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,658,910
Number of Sequences: 37866
Number of extensions: 815626
Number of successful extensions: 1893
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1882
Number of HSP's gapped (non-prelim): 23
length of query: 571
length of database: 18,247,518
effective HSP length: 108
effective length of query: 463
effective length of database: 14,157,990
effective search space: 6555149370
effective search space used: 6555149370
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.