Guide to the Human Genome
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Name: HMGCS2 Sequence: fasta or formatted (508aa) NCBI GI: 5031751
Description:

hydroxymethylglutaryl-CoA synthase 2

Referenced in:

Cholesterol Biosynthesis
Fatty Acid Oxidation and Ketone Bodies
Mitochondria

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.1         41           2
 C cysteine            1.8          9           1
 D aspartate           5.9         30           2
 E glutamate           4.5         23           2
 F phenylalanine       4.1         21           2
 G glycine             6.7         34           2
 H histidine           1.6          8           2
 I isoleucine          3.1         16           2
 K lysine              5.7         29           2
 L leucine            10.6         54           2
 M methionine          2.8         14           1
 N asparagine          3.5         18           2
 P proline             4.5         23           2
 Q glutamine           4.7         24           1
 R arginine            5.5         28           2
 S serine              8.7         44           3
 T threonine           6.7         34           2
 V valine              5.7         29           2
 W tryptophan          1.2          6           1
 Y tyrosine            4.5         23           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   hydroxymethylglutaryl-CoA synthase 2 
HMGCS1                0.641   hydroxymethylglutaryl-CoA synthase 1 
HMGCS1                0.641   hydroxymethylglutaryl-CoA synthase 1 
APLP1                 0.005   amyloid precursor-like protein 1 isoform 2 precursor ...
SLC40A1               0.005   solute carrier family 40 (iron-regulated transporter)...
LOC100291802          0.005   PREDICTED: hypothetical protein XP_002346199 
LOC100291215          0.005   PREDICTED: hypothetical protein XP_002347079 
LOC100287684          0.005   PREDICTED: hypothetical protein XP_002342945 
RASSF5                0.004   Ras association (RalGDS/AF-6) domain family 5 isofor...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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