Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 7656993
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7656993 copine 7 isoform b [Homo sapiens]
(633 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7656993 copine 7 isoform b [Homo sapiens] 1298 0.0
gi|25141328 copine 7 isoform a [Homo sapiens] 892 0.0
gi|18677733 copine IV [Homo sapiens] 657 0.0
gi|5174421 copine 6 [Homo sapiens] 627 e-180
gi|4503015 copine III [Homo sapiens] 505 e-143
gi|30181236 copine II [Homo sapiens] 502 e-142
gi|25141323 copine V [Homo sapiens] 474 e-133
gi|23397708 copine I isoform a [Homo sapiens] 454 e-128
gi|23397706 copine I isoform a [Homo sapiens] 454 e-128
gi|23397704 copine I isoform a [Homo sapiens] 454 e-128
gi|23397702 copine I isoform a [Homo sapiens] 454 e-128
gi|23397700 copine I isoform a [Homo sapiens] 454 e-128
gi|23397698 copine I isoform a [Homo sapiens] 454 e-128
gi|23397696 copine I isoform a [Homo sapiens] 454 e-128
gi|197333761 copine I isoform b [Homo sapiens] 454 e-128
gi|25121972 copine VIII [Homo sapiens] 421 e-118
gi|88703066 copine-like protein [Homo sapiens] 399 e-111
gi|47157322 protein kinase C, beta isoform 1 [Homo sapiens] 52 2e-06
gi|20127450 protein kinase C, beta isoform 2 [Homo sapiens] 52 2e-06
gi|13384594 protein kinase C, gamma [Homo sapiens] 50 8e-06
gi|150170670 piccolo isoform 2 [Homo sapiens] 46 1e-04
gi|150378539 piccolo isoform 1 [Homo sapiens] 46 1e-04
gi|4506067 protein kinase C, alpha [Homo sapiens] 45 2e-04
gi|209447073 synaptotagmin I [Homo sapiens] 44 5e-04
gi|5032139 synaptotagmin I [Homo sapiens] 44 5e-04
gi|209447070 synaptotagmin I [Homo sapiens] 44 5e-04
gi|28376627 synaptotagmin IX [Homo sapiens] 43 0.001
gi|238550198 synaptotagmin III [Homo sapiens] 42 0.002
gi|238550196 synaptotagmin III [Homo sapiens] 42 0.002
gi|14150054 synaptotagmin III [Homo sapiens] 42 0.002
>gi|7656993 copine 7 isoform b [Homo sapiens]
Length = 633
Score = 1298 bits (3360), Expect = 0.0
Identities = 633/633 (100%), Positives = 633/633 (100%)
Query: 1 MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVG 60
MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVG
Sbjct: 1 MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVG 60
Query: 61 RTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQP 120
RTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQP
Sbjct: 61 RTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQP 120
Query: 121 AQKWLLQVVMRVSVDVLGPAGHCAKHFLCCTESSHLARTGPSFLLRYDDLCLPWATAGAV 180
AQKWLLQVVMRVSVDVLGPAGHCAKHFLCCTESSHLARTGPSFLLRYDDLCLPWATAGAV
Sbjct: 121 AQKWLLQVVMRVSVDVLGPAGHCAKHFLCCTESSHLARTGPSFLLRYDDLCLPWATAGAV 180
Query: 181 RWWTCRGGHTQGWQIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARK 240
RWWTCRGGHTQGWQIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARK
Sbjct: 181 RWWTCRGGHTQGWQIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARK 240
Query: 241 LDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRP 300
LDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRP
Sbjct: 241 LDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRP 300
Query: 301 LKCLVWDYDSRGKHDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVL 360
LKCLVWDYDSRGKHDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVL
Sbjct: 301 LKCLVWDYDSRGKHDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVL 360
Query: 361 ADLKFHRVYSFLDYIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSV 420
ADLKFHRVYSFLDYIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSV
Sbjct: 361 ADLKFHRVYSFLDYIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSV 420
Query: 421 GEICQDYDSDKRFSALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRV 480
GEICQDYDSDKRFSALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRV
Sbjct: 421 GEICQDYDSDKRFSALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRV 480
Query: 481 QLYGPTNVAPIISKVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPM 540
QLYGPTNVAPIISKVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPM
Sbjct: 481 QLYGPTNVAPIISKVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPM 540
Query: 541 SIIIVGVGNADFTDMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLA 600
SIIIVGVGNADFTDMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLA
Sbjct: 541 SIIIVGVGNADFTDMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLA 600
Query: 601 EVPKQVVEYYSHRGLPPRSLGVPAGEASPGCTP 633
EVPKQVVEYYSHRGLPPRSLGVPAGEASPGCTP
Sbjct: 601 EVPKQVVEYYSHRGLPPRSLGVPAGEASPGCTP 633
>gi|25141328 copine 7 isoform a [Homo sapiens]
Length = 558
Score = 892 bits (2304), Expect = 0.0
Identities = 440/440 (100%), Positives = 440/440 (100%)
Query: 194 QIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPF 253
QIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPF
Sbjct: 119 QIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPF 178
Query: 254 LELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGK 313
LELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGK
Sbjct: 179 LELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGK 238
Query: 314 HDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLD 373
HDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLD
Sbjct: 239 HDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLD 298
Query: 374 YIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRF 433
YIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRF
Sbjct: 299 YIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRF 358
Query: 434 SALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIIS 493
SALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIIS
Sbjct: 359 SALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIIS 418
Query: 494 KVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFT 553
KVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFT
Sbjct: 419 KVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFT 478
Query: 554 DMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHR 613
DMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHR
Sbjct: 479 DMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHR 538
Query: 614 GLPPRSLGVPAGEASPGCTP 633
GLPPRSLGVPAGEASPGCTP
Sbjct: 539 GLPPRSLGVPAGEASPGCTP 558
Score = 246 bits (628), Expect = 5e-65
Identities = 119/119 (100%), Positives = 119/119 (100%)
Query: 1 MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVG 60
MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVG
Sbjct: 1 MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVG 60
Query: 61 RTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQ 119
RTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQ
Sbjct: 61 RTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQ 119
Score = 41.6 bits (96), Expect = 0.002
Identities = 41/132 (31%), Positives = 63/132 (47%), Gaps = 8/132 (6%)
Query: 232 VELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVW-EAFKVSLS 290
VEL R L D+D +KSDP + L + Q +Q V RTEVV+++L+PV+ + F V
Sbjct: 24 VELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQ-VGRTEVVRSSLHPVFSKVFTVDY- 81
Query: 291 SLCSCEETRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRR 350
EE + L+ V YD+ G F + M+ + AQ P + R
Sbjct: 82 ---YFEEVQRLRFEV--YDTHGPSGFSCQEDDFLGGMECTLGQIVAQKKVTRPLLLKFGR 136
Query: 351 SYKNSGVVVLAD 362
+ S + V+A+
Sbjct: 137 NAGKSTITVIAE 148
Score = 39.7 bits (91), Expect = 0.009
Identities = 36/100 (36%), Positives = 52/100 (52%), Gaps = 15/100 (15%)
Query: 24 VELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQ-VGRTEVVRSSLHPVFSKVFTVDY- 81
VEL R L D+D +KSDP + L + Q +Q V RTEVV+++L+PV+ + F V
Sbjct: 157 VELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVW-EAFKVSLS 215
Query: 82 ---YFEEVQRLRFEV--YDTHGPSGFSCQEDDFLGGMECT 116
EE + L+ V YD+ G + DF+G T
Sbjct: 216 SLCSCEETRPLKCLVWDYDSRG-------KHDFIGEFSTT 248
>gi|18677733 copine IV [Homo sapiens]
Length = 557
Score = 657 bits (1694), Expect = 0.0
Identities = 313/425 (73%), Positives = 374/425 (88%), Gaps = 1/425 (0%)
Query: 194 QIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPF 253
QIV+Q+K+++ LL K G AGKS+ITVIAE++SGN+ YVEL+F ARKLDDKD FSKSDPF
Sbjct: 120 QIVSQRKLSKSLL-KHGNTAGKSSITVIAEELSGNDDYVELAFNARKLDDKDFFSKSDPF 178
Query: 254 LELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGK 313
LE++R+NDD QLV+RTEVV NNL+P W++FKVS++SLCS + R LKC+VWD+DS GK
Sbjct: 179 LEIFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNGK 238
Query: 314 HDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLD 373
HDFIGEF++TF+EM+ A E Q QW+C+NPKYK K+++YKNSG V+L K H+++SFLD
Sbjct: 239 HDFIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKNSGTVILNLCKIHKMHSFLD 298
Query: 374 YIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRF 433
YIMGGCQI FTVAIDFTASNGDPRNSCSLHYI+PYQPNEYLKALV+VGEICQDYDSDK F
Sbjct: 299 YIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMF 358
Query: 434 SALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIIS 493
A GFGARIPP+Y VSHDFAINFN ++ EC GIQGVVEAYQ+CLP++QLYGPTN+APII
Sbjct: 359 PAFGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQ 418
Query: 494 KVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFT 553
KVA+ A+ E +T +ASQY+ILLILTDGV+TDMADTREAIV AS LPMS+IIVGVGNADF+
Sbjct: 419 KVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFS 478
Query: 554 DMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHR 613
DMQ+LDGDDG+LRSP+GEP LRDIVQFVPFR K+ASPAALAK VLAEVP QVV+YY+ +
Sbjct: 479 DMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGK 538
Query: 614 GLPPR 618
G+ P+
Sbjct: 539 GIKPK 543
Score = 132 bits (333), Expect = 7e-31
Identities = 65/111 (58%), Positives = 83/111 (74%), Gaps = 1/111 (0%)
Query: 9 AAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSS 68
AA T G +PC +KVELR++C+ + DRD L+K DP V L Q+ GQW +V RTEV+R+
Sbjct: 11 AANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFEVDRTEVIRTC 70
Query: 69 LHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQ 119
++PV+SK+FTVD+YFEEVQRLRFEV+D +E DFLGGMECTLGQ
Sbjct: 71 INPVYSKLFTVDFYFEEVQRLRFEVHDISSNHN-GLKEADFLGGMECTLGQ 120
Score = 35.4 bits (80), Expect = 0.16
Identities = 31/101 (30%), Positives = 48/101 (47%), Gaps = 10/101 (9%)
Query: 232 VELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVW-EAFKVSLS 290
VEL + + D+D SK DP + L + Q + V RTEV++ +NPV+ + F V
Sbjct: 26 VELRVACKGISDRDALSKPDPCVILKMQSHGQWFE-VDRTEVIRTCINPVYSKLFTVDF- 83
Query: 291 SLCSCEETRPLKCLVWDYDSR----GKHDFIGEFSTTFEEM 327
EE + L+ V D S + DF+G T ++
Sbjct: 84 ---YFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQI 121
Score = 32.7 bits (73), Expect = 1.0
Identities = 20/51 (39%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 24 VELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQ-VGRTEVVRSSLHPVF 73
VEL + R L D+D +KSDP + + + Q V RTEVV ++L P +
Sbjct: 157 VELAFNARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLSPAW 207
>gi|5174421 copine 6 [Homo sapiens]
Length = 557
Score = 627 bits (1618), Expect = e-180
Identities = 301/426 (70%), Positives = 368/426 (86%), Gaps = 2/426 (0%)
Query: 194 QIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPF 253
QIV+Q KVT+PLLLK G+ AGKSTIT++AE++SG N YV+L+FRA KLD+KDLFSKSDPF
Sbjct: 116 QIVSQTKVTKPLLLKNGKTAGKSTITIVAEEVSGTNDYVQLTFRAYKLDNKDLFSKSDPF 175
Query: 254 LELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGK 313
+E+Y+ N+DQ QLV+RTEVVKNNLNP WE F++SL SLCSC+ RPLK LV+DYDS GK
Sbjct: 176 MEIYKTNEDQSDQLVWRTEVVKNNLNPSWEPFRLSLHSLCSCDVHRPLKFLVYDYDSSGK 235
Query: 314 HDFIGEFSTTFEEMQK--AFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSF 371
HDFIGEF++TF+EMQ+ A + QWDC+NPKY+ K+++YK+SG VVLA +V++F
Sbjct: 236 HDFIGEFTSTFQEMQEGTANPGQEMQWDCINPKYRDKKKNYKSSGTVVLAQCTVEKVHTF 295
Query: 372 LDYIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDK 431
LDYIMGGCQI FTVAIDFTASNGDPR+S SLH ++P QPN YL+AL +VG ICQDYDSDK
Sbjct: 296 LDYIMGGCQISFTVAIDFTASNGDPRSSQSLHCLSPRQPNHYLQALRAVGGICQDYDSDK 355
Query: 432 RFSALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPI 491
RF A GFGARIPP +EVSHDFAINF+PE+ ECE I GV+ +Y+ CLP++QLYGPTNVAPI
Sbjct: 356 RFPAFGFGARIPPNFEVSHDFAINFDPENPECEEISGVIASYRRCLPQIQLYGPTNVAPI 415
Query: 492 ISKVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNAD 551
I++VA A E+STG+A++Y +LL+LTDGVV+DMA+TR AIVRASRLPMSIIIVGVGNAD
Sbjct: 416 INRVAEPAQREQSTGQATKYSVLLVLTDGVVSDMAETRTAIVRASRLPMSIIIVGVGNAD 475
Query: 552 FTDMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYS 611
F+DM++LDGDDG LR PRG PA RDIVQFVPFR+ K+A+P+ALAKCVLAEVP+QVVEYY+
Sbjct: 476 FSDMRLLDGDDGPLRCPRGVPAARDIVQFVPFRDFKDAAPSALAKCVLAEVPRQVVEYYA 535
Query: 612 HRGLPP 617
+G+ P
Sbjct: 536 SQGISP 541
Score = 102 bits (254), Expect = 1e-21
Identities = 54/99 (54%), Positives = 66/99 (66%), Gaps = 1/99 (1%)
Query: 21 ASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVFSKVFTVD 80
AS+VELR+SC LLDRD LTK P V L + QWV+V RTEV+RS PVFS+V ++
Sbjct: 19 ASRVELRVSCHGLLDRDTLTKPHPCVLLKLYSDEQWVEVERTEVLRSCSSPVFSRVLALE 78
Query: 81 YYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQ 119
Y+FEE Q L+F V+D S + D FLG ECTLGQ
Sbjct: 79 YFFEEKQPLQFHVFDAE-DGATSPRNDTFLGSTECTLGQ 116
Score = 32.0 bits (71), Expect = 1.8
Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 4/76 (5%)
Query: 232 VELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSS 291
VEL L D+D +K P + L +D+Q ++ V RTEV+++ +PV F L+
Sbjct: 22 VELRVSCHGLLDRDTLTKPHPCVLLKLYSDEQWVE-VERTEVLRSCSSPV---FSRVLAL 77
Query: 292 LCSCEETRPLKCLVWD 307
EE +PL+ V+D
Sbjct: 78 EYFFEEKQPLQFHVFD 93
Score = 30.8 bits (68), Expect = 4.0
Identities = 31/97 (31%), Positives = 51/97 (52%), Gaps = 9/97 (9%)
Query: 24 VELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQ-VGRTEVVRSSLHPVFS--KVFTVD 80
V+L L ++D +KSDP + + + + Q Q V RTEVV+++L+P + ++
Sbjct: 154 VQLTFRAYKLDNKDLFSKSDPFMEIYKTNEDQSDQLVWRTEVVKNNLNPSWEPFRLSLHS 213
Query: 81 YYFEEVQR-LRFEVYDTHGPSGFSCQEDDFLGGMECT 116
+V R L+F VYD + SG + DF+G T
Sbjct: 214 LCSCDVHRPLKFLVYD-YDSSG----KHDFIGEFTST 245
>gi|4503015 copine III [Homo sapiens]
Length = 537
Score = 505 bits (1301), Expect = e-143
Identities = 247/427 (57%), Positives = 325/427 (76%), Gaps = 2/427 (0%)
Query: 194 QIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPF 253
QIV+ KK+TRPL++K GR AGK +IT+ AE+I N V ARKLD+KDLF KSDP+
Sbjct: 104 QIVSSKKLTRPLVMKTGRPAGKGSITISAEEIKDNR-VVLFEMEARKLDNKDLFGKSDPY 162
Query: 254 LELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGK 313
LE ++ D +V+RTEVVKNNLNPVW FK+SL+SLC + + +K +DYD+ G
Sbjct: 163 LEFHKQTSDGNWLMVHRTEVVKNNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGS 222
Query: 314 HDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLD 373
HD IG F TT ++++A +++C+N K +QK++SYKNSGV+ + + +FLD
Sbjct: 223 HDLIGTFQTTMTKLKEASRSSPVEFECINEKKRQKKKSYKNSGVISVKQCEITVECTFLD 282
Query: 374 YIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRF 433
YIMGGCQ++FTV +DFT SNGDPR+ SLHYI+P NEYL AL SVG + QDYD+DK F
Sbjct: 283 YIMGGCQLNFTVGVDFTGSNGDPRSPDSLHYISPNGVNEYLTALWSVGLVIQDYDADKMF 342
Query: 434 SALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIIS 493
A GFGA+IPP+++VSH+F +NFNP + C GIQG+VEAY++CLP+++LYGPTN +PII+
Sbjct: 343 PAFGFGAQIPPQWQVSHEFPMNFNPSNPYCNGIQGIVEAYRSCLPQIKLYGPTNFSPIIN 402
Query: 494 KVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFT 553
VAR AAA ASQY++LLI+TDGV+TD+ +TR+AIV ASRLPMSIIIVGVG ADF+
Sbjct: 403 HVARFAAAATQQQTASQYFVLLIITDGVITDLDETRQAIVNASRLPMSIIIVGVGGADFS 462
Query: 554 DMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYY-SH 612
M+ LDGD G LRSP GE A+RDIVQFVPFR+ +NA ALA+CVLAE+P+QVV Y+ ++
Sbjct: 463 AMEFLDGDGGSLRSPLGEVAIRDIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNTY 522
Query: 613 RGLPPRS 619
+ LPP++
Sbjct: 523 KLLPPKN 529
Score = 102 bits (253), Expect = 1e-21
Identities = 52/105 (49%), Positives = 68/105 (64%), Gaps = 2/105 (1%)
Query: 16 LPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQ-WVQVGRTEVVRSSLHPVFS 74
+ A C +KV L +SC +LLD+D +KSDP L GQ W +V RTE +++ L+P FS
Sbjct: 1 MAAQCVTKVALNVSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFS 60
Query: 75 KVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQ 119
K F +DYYFE VQ+L+F VYD + +DDFLG ECTLGQ
Sbjct: 61 KTFIIDYYFEVVQKLKFGVYDIDNKT-IELSDDDFLGECECTLGQ 104
Score = 42.0 bits (97), Expect = 0.002
Identities = 34/100 (34%), Positives = 46/100 (46%), Gaps = 7/100 (7%)
Query: 232 VELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSS 291
V L+ L DKD+ SKSDP L+ Q V RTE +KN LNP F +
Sbjct: 9 VALNVSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNP---QFSKTFII 65
Query: 292 LCSCEETRPLKCLVWDYDSR----GKHDFIGEFSTTFEEM 327
E + LK V+D D++ DF+GE T ++
Sbjct: 66 DYYFEVVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQI 105
Score = 38.5 bits (88), Expect = 0.019
Identities = 25/77 (32%), Positives = 43/77 (55%), Gaps = 6/77 (7%)
Query: 24 VELRLSCRHLLDRDPLTKSDPSVALLQQ-AQGQWVQVGRTEVVRSSLHPVFSKVFTVDY- 81
V + R L ++D KSDP + +Q + G W+ V RTEVV+++L+PV+ + F +
Sbjct: 141 VLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVVKNNLNPVW-RPFKISLN 199
Query: 82 ---YFEEVQRLRFEVYD 95
Y + + ++ E YD
Sbjct: 200 SLCYGDMDKTIKVECYD 216
>gi|30181236 copine II [Homo sapiens]
Length = 548
Score = 502 bits (1292), Expect = e-142
Identities = 240/423 (56%), Positives = 317/423 (74%), Gaps = 1/423 (0%)
Query: 195 IVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFL 254
IV+ KK+TRPLLL + AGK IT+ A+++S N + LS R+LD KDLF KSDPFL
Sbjct: 121 IVSSKKITRPLLLLNDKPAGKGLITIAAQELSDNR-VITLSLAGRRLDKKDLFGKSDPFL 179
Query: 255 ELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGKH 314
E Y+ DD LV+RTEV+K L+PVW+ F V L SLC + +P++ + +DYD+ G H
Sbjct: 180 EFYKPGDDGKWMLVHRTEVIKYTLDPVWKPFTVPLVSLCDGDMEKPIQVMCYDYDNDGGH 239
Query: 315 DFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLDY 374
DFIGEF T+ +M +A + +++C+NPK ++K+++YKNSG+++L K +R YSFLDY
Sbjct: 240 DFIGEFQTSVSQMCEARDSVPLEFECINPKKQRKKKNYKNSGIIILRSCKINRDYSFLDY 299
Query: 375 IMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRFS 434
I+GGCQ+ FTV IDFTASNG+P + SLHYINP NEYL A+ +VG+I QDYDSDK F
Sbjct: 300 ILGGCQLMFTVGIDFTASNGNPLDPSSLHYINPMGTNEYLSAIWAVGQIIQDYDSDKMFP 359
Query: 435 ALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISK 494
ALGFGA++PP ++VSH+FAINFNP + C G+ G+ +AY CLP ++ YGPTN +PI++
Sbjct: 360 ALGFGAQLPPDWKVSHEFAINFNPTNPFCSGVDGIAQAYSACLPHIRFYGPTNFSPIVNH 419
Query: 495 VARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFTD 554
VAR AA A+QY+ILLI+TDGV++DM +TR A+V+AS+LPMSIIIVGVGNADF
Sbjct: 420 VARFAAQATQQRTATQYFILLIITDGVISDMEETRHAVVQASKLPMSIIIVGVGNADFAA 479
Query: 555 MQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHRG 614
M+ LDGD +LRS GE A RDIVQFVPFRE +NA+ LAK VLAE+P+QVV+Y+ H+
Sbjct: 480 MEFLDGDSRMLRSHTGEEAARDIVQFVPFREFRNAAKETLAKAVLAELPQQVVQYFKHKN 539
Query: 615 LPP 617
LPP
Sbjct: 540 LPP 542
Score = 100 bits (249), Expect = 4e-21
Identities = 52/116 (44%), Positives = 71/116 (61%), Gaps = 2/116 (1%)
Query: 3 AGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRT 62
+G A A P G P C KVEL +S ++LLDRD +KSDP L + G+W++ RT
Sbjct: 6 SGGAPAAGAAPMG-PQYCVCKVELSVSGQNLLDRDVTSKSDPFCVLFTENNGRWIEYDRT 64
Query: 63 EVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLG 118
E ++L+P FSK F +DY+FEEVQ+L+F ++D S E DFLG C+LG
Sbjct: 65 ETAINNLNPAFSKKFVLDYHFEEVQKLKFALFD-QDKSSMRLDEHDFLGQFSCSLG 119
Score = 55.1 bits (131), Expect = 2e-07
Identities = 37/94 (39%), Positives = 51/94 (54%), Gaps = 8/94 (8%)
Query: 232 VELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSS 291
VELS + L D+D+ SKSDPF L+ N+ + ++ RTE NNLNP AF
Sbjct: 26 VELSVSGQNLLDRDVTSKSDPFCVLFTENNGRWIE-YDRTETAINNLNP---AFSKKFVL 81
Query: 292 LCSCEETRPLKCLVWDYDSRG----KHDFIGEFS 321
EE + LK ++D D +HDF+G+FS
Sbjct: 82 DYHFEEVQKLKFALFDQDKSSMRLDEHDFLGQFS 115
Score = 37.4 bits (85), Expect = 0.042
Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 15/103 (14%)
Query: 24 VELRLSCRHLLDRDPLTKSDPSVALLQQAQ-GQWVQVGRTEVVRSSLHPVFSKVFTV--- 79
+ L L+ R L +D KSDP + + G+W+ V RTEV++ +L PV+ K FTV
Sbjct: 157 ITLSLAGRRLDKKDLFGKSDPFLEFYKPGDDGKWMLVHRTEVIKYTLDPVW-KPFTVPLV 215
Query: 80 ---DYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQ 119
D E+ ++ YD G DF+G + ++ Q
Sbjct: 216 SLCDGDMEKPIQVMCYDYDNDG-------GHDFIGEFQTSVSQ 251
>gi|25141323 copine V [Homo sapiens]
Length = 593
Score = 474 bits (1220), Expect = e-133
Identities = 283/634 (44%), Positives = 371/634 (58%), Gaps = 81/634 (12%)
Query: 14 GGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQG--QWVQVGRTEVVRSSLHP 71
G +PA +KVE+ +SCR+LLD+D +KSDP + Q QW + GRTEV+ ++L+P
Sbjct: 18 GSIPA---TKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNP 74
Query: 72 VFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQPAQKWLLQVVMR 131
F + F VDY+FEE Q LRF++YD S + DFLG CTLG+
Sbjct: 75 DFVRKFIVDYFFEEKQNLRFDLYDVDSKSP-DLSKHDFLGQAFCTLGE------------ 121
Query: 132 VSVDVLGPAGHCAKHFLCCTESSHLARTGPSFLLRYDDLCLPWATAGAVRWWTCRGGHTQ 191
++G G + L S +RTG +P + G V C
Sbjct: 122 ----IVGSPGSRLEKPLTIGAFSLNSRTGKP---------MPAVSNGGVPGKKC------ 162
Query: 192 GWQIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSD 251
TI + AE++S + F A KLD KD F KSD
Sbjct: 163 ------------------------GTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSD 198
Query: 252 PFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSR 311
PFL YR N+D + ++TEV+KN LNPVW+ F + + +LC+ + R +K V+D+D
Sbjct: 199 PFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRD 258
Query: 312 GKHDFIGEFSTTFEEMQKAFEEGQAQ---WDCVNPKYKQKRRSYKNSGVVVLADLKFHRV 368
G HDFIGEF+T++ E+ + GQ+Q ++ VNPK K K++ Y NSG V L
Sbjct: 259 GSHDFIGEFTTSYRELAR----GQSQFNIYEVVNPKKKMKKKKYVNSGTVTLLSFAVESE 314
Query: 369 YSFLDYIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYD 428
+FLDYI GG QI+FTVAIDFTASNG+P S SLHY++PYQ N Y AL +VGEI Q YD
Sbjct: 315 CTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYD 374
Query: 429 SDKRFSALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNV 488
SDK F ALGFGA++PP VSH+F +N N E+ C GI G++EAY L VQLYGPTN
Sbjct: 375 SDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLYGPTNF 434
Query: 489 APIISKVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVG 548
AP+++ VAR AAA + SQY +LLI+TDGV++DMA T+EAIV A++LPMSIIIVGVG
Sbjct: 435 APVVTHVARNAAAVQD---GSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVG 491
Query: 549 NADFTDMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKN------ASPAALAKCVLAEV 602
A+F M LDGDD V S RG+ A RDIVQFVPFR+ + S A LA+ VLAE+
Sbjct: 492 QAEFDAMVELDGDD-VRISSRGKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEI 550
Query: 603 PKQVVEYYSHRGL---PPRSLGVPAGEASPGCTP 633
P Q+V Y +G+ PP + + SP TP
Sbjct: 551 PDQLVSYMKAQGIRPRPPPAAPTHSPSQSPARTP 584
>gi|23397708 copine I isoform a [Homo sapiens]
Length = 537
Score = 454 bits (1169), Expect = e-128
Identities = 228/424 (53%), Positives = 297/424 (70%), Gaps = 6/424 (1%)
Query: 194 QIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPF 253
QIV+ + +T PL+LK G+ AG+ TITV A+++ N V + AR LD KD KSDPF
Sbjct: 103 QIVSSQVLTLPLMLKPGKPAGRGTITVSAQELKDNR-VVTMEVEARNLDKKDFLGKSDPF 161
Query: 254 LELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGK 313
LE +R D + LVYR+EV+KNNLNP W+ F V + C + P++ DYDS G
Sbjct: 162 LEFFRQGDGKW-HLVYRSEVIKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGS 220
Query: 314 HDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLD 373
HD IG F T+ ++Q A+++C++P+ +QK++SYKNSG + + + YSFLD
Sbjct: 221 HDLIGTFHTSLAQLQAV----PAEFECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLD 276
Query: 374 YIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRF 433
Y+MGGCQI+FTV +DFT SNGDP + SLHY++P NEYL AL SVG + QDYDSDK F
Sbjct: 277 YVMGGCQINFTVGVDFTGSNGDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLF 336
Query: 434 SALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIIS 493
A GFGA++PP ++VSH+FA+NFNP + C GIQG+V+AY+ LP+V+LYGPTN APII+
Sbjct: 337 PAFGFGAQVPPDWQVSHEFALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIIN 396
Query: 494 KVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFT 553
VAR AA G ASQY++LL+LTDG VTD+ TREA+VRAS LPMS+IIVGVG ADF
Sbjct: 397 HVARFAAQAAHQGTASQYFMLLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFE 456
Query: 554 DMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHR 613
M+ LD D G L + G+ A RDIVQFVP+R +NA ALA+ VLAEVP Q+V Y+ +
Sbjct: 457 AMEQLDADGGPLHTRSGQAAARDIVQFVPYRRFQNAPREALAQTVLAEVPTQLVSYFRAQ 516
Query: 614 GLPP 617
G P
Sbjct: 517 GWAP 520
Score = 97.8 bits (242), Expect = 3e-20
Identities = 50/103 (48%), Positives = 67/103 (65%), Gaps = 2/103 (1%)
Query: 18 APCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQG-QWVQVGRTEVVRSSLHPVFSKV 76
A C + V+L +SC HL+D+D +KSDP LLQ G W ++GRTE VR+ P FSK
Sbjct: 2 AHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSPEFSKT 61
Query: 77 FTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQ 119
++Y FE VQ+LRF +YD + ++DDFLGG EC+LGQ
Sbjct: 62 LQLEYRFETVQKLRFGIYDIDNKTP-ELRDDDFLGGAECSLGQ 103
Score = 40.8 bits (94), Expect = 0.004
Identities = 18/52 (34%), Positives = 33/52 (63%)
Query: 24 VELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVFSK 75
V + + R+L +D L KSDP + +Q G+W V R+EV++++L+P + +
Sbjct: 140 VTMEVEARNLDKKDFLGKSDPFLEFFRQGDGKWHLVYRSEVIKNNLNPTWKR 191
Score = 32.3 bits (72), Expect = 1.4
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
Query: 232 VELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSS 291
V+LS L DKD+ SKSDP L + + RTE V+N +P F +L
Sbjct: 8 VQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSP---EFSKTLQL 64
Query: 292 LCSCEETRPLKCLVWDYDSRGKH----DFIG 318
E + L+ ++D D++ DF+G
Sbjct: 65 EYRFETVQKLRFGIYDIDNKTPELRDDDFLG 95
>gi|23397706 copine I isoform a [Homo sapiens]
Length = 537
Score = 454 bits (1169), Expect = e-128
Identities = 228/424 (53%), Positives = 297/424 (70%), Gaps = 6/424 (1%)
Query: 194 QIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPF 253
QIV+ + +T PL+LK G+ AG+ TITV A+++ N V + AR LD KD KSDPF
Sbjct: 103 QIVSSQVLTLPLMLKPGKPAGRGTITVSAQELKDNR-VVTMEVEARNLDKKDFLGKSDPF 161
Query: 254 LELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGK 313
LE +R D + LVYR+EV+KNNLNP W+ F V + C + P++ DYDS G
Sbjct: 162 LEFFRQGDGKW-HLVYRSEVIKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGS 220
Query: 314 HDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLD 373
HD IG F T+ ++Q A+++C++P+ +QK++SYKNSG + + + YSFLD
Sbjct: 221 HDLIGTFHTSLAQLQAV----PAEFECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLD 276
Query: 374 YIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRF 433
Y+MGGCQI+FTV +DFT SNGDP + SLHY++P NEYL AL SVG + QDYDSDK F
Sbjct: 277 YVMGGCQINFTVGVDFTGSNGDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLF 336
Query: 434 SALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIIS 493
A GFGA++PP ++VSH+FA+NFNP + C GIQG+V+AY+ LP+V+LYGPTN APII+
Sbjct: 337 PAFGFGAQVPPDWQVSHEFALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIIN 396
Query: 494 KVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFT 553
VAR AA G ASQY++LL+LTDG VTD+ TREA+VRAS LPMS+IIVGVG ADF
Sbjct: 397 HVARFAAQAAHQGTASQYFMLLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFE 456
Query: 554 DMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHR 613
M+ LD D G L + G+ A RDIVQFVP+R +NA ALA+ VLAEVP Q+V Y+ +
Sbjct: 457 AMEQLDADGGPLHTRSGQAAARDIVQFVPYRRFQNAPREALAQTVLAEVPTQLVSYFRAQ 516
Query: 614 GLPP 617
G P
Sbjct: 517 GWAP 520
Score = 97.8 bits (242), Expect = 3e-20
Identities = 50/103 (48%), Positives = 67/103 (65%), Gaps = 2/103 (1%)
Query: 18 APCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQG-QWVQVGRTEVVRSSLHPVFSKV 76
A C + V+L +SC HL+D+D +KSDP LLQ G W ++GRTE VR+ P FSK
Sbjct: 2 AHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSPEFSKT 61
Query: 77 FTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQ 119
++Y FE VQ+LRF +YD + ++DDFLGG EC+LGQ
Sbjct: 62 LQLEYRFETVQKLRFGIYDIDNKTP-ELRDDDFLGGAECSLGQ 103
Score = 40.8 bits (94), Expect = 0.004
Identities = 18/52 (34%), Positives = 33/52 (63%)
Query: 24 VELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVFSK 75
V + + R+L +D L KSDP + +Q G+W V R+EV++++L+P + +
Sbjct: 140 VTMEVEARNLDKKDFLGKSDPFLEFFRQGDGKWHLVYRSEVIKNNLNPTWKR 191
Score = 32.3 bits (72), Expect = 1.4
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
Query: 232 VELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSS 291
V+LS L DKD+ SKSDP L + + RTE V+N +P F +L
Sbjct: 8 VQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSP---EFSKTLQL 64
Query: 292 LCSCEETRPLKCLVWDYDSRGKH----DFIG 318
E + L+ ++D D++ DF+G
Sbjct: 65 EYRFETVQKLRFGIYDIDNKTPELRDDDFLG 95
>gi|23397704 copine I isoform a [Homo sapiens]
Length = 537
Score = 454 bits (1169), Expect = e-128
Identities = 228/424 (53%), Positives = 297/424 (70%), Gaps = 6/424 (1%)
Query: 194 QIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPF 253
QIV+ + +T PL+LK G+ AG+ TITV A+++ N V + AR LD KD KSDPF
Sbjct: 103 QIVSSQVLTLPLMLKPGKPAGRGTITVSAQELKDNR-VVTMEVEARNLDKKDFLGKSDPF 161
Query: 254 LELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGK 313
LE +R D + LVYR+EV+KNNLNP W+ F V + C + P++ DYDS G
Sbjct: 162 LEFFRQGDGKW-HLVYRSEVIKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGS 220
Query: 314 HDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLD 373
HD IG F T+ ++Q A+++C++P+ +QK++SYKNSG + + + YSFLD
Sbjct: 221 HDLIGTFHTSLAQLQAV----PAEFECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLD 276
Query: 374 YIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRF 433
Y+MGGCQI+FTV +DFT SNGDP + SLHY++P NEYL AL SVG + QDYDSDK F
Sbjct: 277 YVMGGCQINFTVGVDFTGSNGDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLF 336
Query: 434 SALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIIS 493
A GFGA++PP ++VSH+FA+NFNP + C GIQG+V+AY+ LP+V+LYGPTN APII+
Sbjct: 337 PAFGFGAQVPPDWQVSHEFALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIIN 396
Query: 494 KVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFT 553
VAR AA G ASQY++LL+LTDG VTD+ TREA+VRAS LPMS+IIVGVG ADF
Sbjct: 397 HVARFAAQAAHQGTASQYFMLLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFE 456
Query: 554 DMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHR 613
M+ LD D G L + G+ A RDIVQFVP+R +NA ALA+ VLAEVP Q+V Y+ +
Sbjct: 457 AMEQLDADGGPLHTRSGQAAARDIVQFVPYRRFQNAPREALAQTVLAEVPTQLVSYFRAQ 516
Query: 614 GLPP 617
G P
Sbjct: 517 GWAP 520
Score = 97.8 bits (242), Expect = 3e-20
Identities = 50/103 (48%), Positives = 67/103 (65%), Gaps = 2/103 (1%)
Query: 18 APCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQG-QWVQVGRTEVVRSSLHPVFSKV 76
A C + V+L +SC HL+D+D +KSDP LLQ G W ++GRTE VR+ P FSK
Sbjct: 2 AHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSPEFSKT 61
Query: 77 FTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQ 119
++Y FE VQ+LRF +YD + ++DDFLGG EC+LGQ
Sbjct: 62 LQLEYRFETVQKLRFGIYDIDNKTP-ELRDDDFLGGAECSLGQ 103
Score = 40.8 bits (94), Expect = 0.004
Identities = 18/52 (34%), Positives = 33/52 (63%)
Query: 24 VELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVFSK 75
V + + R+L +D L KSDP + +Q G+W V R+EV++++L+P + +
Sbjct: 140 VTMEVEARNLDKKDFLGKSDPFLEFFRQGDGKWHLVYRSEVIKNNLNPTWKR 191
Score = 32.3 bits (72), Expect = 1.4
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
Query: 232 VELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSS 291
V+LS L DKD+ SKSDP L + + RTE V+N +P F +L
Sbjct: 8 VQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSP---EFSKTLQL 64
Query: 292 LCSCEETRPLKCLVWDYDSRGKH----DFIG 318
E + L+ ++D D++ DF+G
Sbjct: 65 EYRFETVQKLRFGIYDIDNKTPELRDDDFLG 95
>gi|23397702 copine I isoform a [Homo sapiens]
Length = 537
Score = 454 bits (1169), Expect = e-128
Identities = 228/424 (53%), Positives = 297/424 (70%), Gaps = 6/424 (1%)
Query: 194 QIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPF 253
QIV+ + +T PL+LK G+ AG+ TITV A+++ N V + AR LD KD KSDPF
Sbjct: 103 QIVSSQVLTLPLMLKPGKPAGRGTITVSAQELKDNR-VVTMEVEARNLDKKDFLGKSDPF 161
Query: 254 LELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGK 313
LE +R D + LVYR+EV+KNNLNP W+ F V + C + P++ DYDS G
Sbjct: 162 LEFFRQGDGKW-HLVYRSEVIKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGS 220
Query: 314 HDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLD 373
HD IG F T+ ++Q A+++C++P+ +QK++SYKNSG + + + YSFLD
Sbjct: 221 HDLIGTFHTSLAQLQAV----PAEFECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLD 276
Query: 374 YIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRF 433
Y+MGGCQI+FTV +DFT SNGDP + SLHY++P NEYL AL SVG + QDYDSDK F
Sbjct: 277 YVMGGCQINFTVGVDFTGSNGDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLF 336
Query: 434 SALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIIS 493
A GFGA++PP ++VSH+FA+NFNP + C GIQG+V+AY+ LP+V+LYGPTN APII+
Sbjct: 337 PAFGFGAQVPPDWQVSHEFALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIIN 396
Query: 494 KVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFT 553
VAR AA G ASQY++LL+LTDG VTD+ TREA+VRAS LPMS+IIVGVG ADF
Sbjct: 397 HVARFAAQAAHQGTASQYFMLLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFE 456
Query: 554 DMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHR 613
M+ LD D G L + G+ A RDIVQFVP+R +NA ALA+ VLAEVP Q+V Y+ +
Sbjct: 457 AMEQLDADGGPLHTRSGQAAARDIVQFVPYRRFQNAPREALAQTVLAEVPTQLVSYFRAQ 516
Query: 614 GLPP 617
G P
Sbjct: 517 GWAP 520
Score = 97.8 bits (242), Expect = 3e-20
Identities = 50/103 (48%), Positives = 67/103 (65%), Gaps = 2/103 (1%)
Query: 18 APCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQG-QWVQVGRTEVVRSSLHPVFSKV 76
A C + V+L +SC HL+D+D +KSDP LLQ G W ++GRTE VR+ P FSK
Sbjct: 2 AHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSPEFSKT 61
Query: 77 FTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQ 119
++Y FE VQ+LRF +YD + ++DDFLGG EC+LGQ
Sbjct: 62 LQLEYRFETVQKLRFGIYDIDNKTP-ELRDDDFLGGAECSLGQ 103
Score = 40.8 bits (94), Expect = 0.004
Identities = 18/52 (34%), Positives = 33/52 (63%)
Query: 24 VELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVFSK 75
V + + R+L +D L KSDP + +Q G+W V R+EV++++L+P + +
Sbjct: 140 VTMEVEARNLDKKDFLGKSDPFLEFFRQGDGKWHLVYRSEVIKNNLNPTWKR 191
Score = 32.3 bits (72), Expect = 1.4
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
Query: 232 VELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSS 291
V+LS L DKD+ SKSDP L + + RTE V+N +P F +L
Sbjct: 8 VQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSP---EFSKTLQL 64
Query: 292 LCSCEETRPLKCLVWDYDSRGKH----DFIG 318
E + L+ ++D D++ DF+G
Sbjct: 65 EYRFETVQKLRFGIYDIDNKTPELRDDDFLG 95
>gi|23397700 copine I isoform a [Homo sapiens]
Length = 537
Score = 454 bits (1169), Expect = e-128
Identities = 228/424 (53%), Positives = 297/424 (70%), Gaps = 6/424 (1%)
Query: 194 QIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPF 253
QIV+ + +T PL+LK G+ AG+ TITV A+++ N V + AR LD KD KSDPF
Sbjct: 103 QIVSSQVLTLPLMLKPGKPAGRGTITVSAQELKDNR-VVTMEVEARNLDKKDFLGKSDPF 161
Query: 254 LELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGK 313
LE +R D + LVYR+EV+KNNLNP W+ F V + C + P++ DYDS G
Sbjct: 162 LEFFRQGDGKW-HLVYRSEVIKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGS 220
Query: 314 HDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLD 373
HD IG F T+ ++Q A+++C++P+ +QK++SYKNSG + + + YSFLD
Sbjct: 221 HDLIGTFHTSLAQLQAV----PAEFECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLD 276
Query: 374 YIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRF 433
Y+MGGCQI+FTV +DFT SNGDP + SLHY++P NEYL AL SVG + QDYDSDK F
Sbjct: 277 YVMGGCQINFTVGVDFTGSNGDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLF 336
Query: 434 SALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIIS 493
A GFGA++PP ++VSH+FA+NFNP + C GIQG+V+AY+ LP+V+LYGPTN APII+
Sbjct: 337 PAFGFGAQVPPDWQVSHEFALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIIN 396
Query: 494 KVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFT 553
VAR AA G ASQY++LL+LTDG VTD+ TREA+VRAS LPMS+IIVGVG ADF
Sbjct: 397 HVARFAAQAAHQGTASQYFMLLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFE 456
Query: 554 DMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHR 613
M+ LD D G L + G+ A RDIVQFVP+R +NA ALA+ VLAEVP Q+V Y+ +
Sbjct: 457 AMEQLDADGGPLHTRSGQAAARDIVQFVPYRRFQNAPREALAQTVLAEVPTQLVSYFRAQ 516
Query: 614 GLPP 617
G P
Sbjct: 517 GWAP 520
Score = 97.8 bits (242), Expect = 3e-20
Identities = 50/103 (48%), Positives = 67/103 (65%), Gaps = 2/103 (1%)
Query: 18 APCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQG-QWVQVGRTEVVRSSLHPVFSKV 76
A C + V+L +SC HL+D+D +KSDP LLQ G W ++GRTE VR+ P FSK
Sbjct: 2 AHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSPEFSKT 61
Query: 77 FTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQ 119
++Y FE VQ+LRF +YD + ++DDFLGG EC+LGQ
Sbjct: 62 LQLEYRFETVQKLRFGIYDIDNKTP-ELRDDDFLGGAECSLGQ 103
Score = 40.8 bits (94), Expect = 0.004
Identities = 18/52 (34%), Positives = 33/52 (63%)
Query: 24 VELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVFSK 75
V + + R+L +D L KSDP + +Q G+W V R+EV++++L+P + +
Sbjct: 140 VTMEVEARNLDKKDFLGKSDPFLEFFRQGDGKWHLVYRSEVIKNNLNPTWKR 191
Score = 32.3 bits (72), Expect = 1.4
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
Query: 232 VELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSS 291
V+LS L DKD+ SKSDP L + + RTE V+N +P F +L
Sbjct: 8 VQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSP---EFSKTLQL 64
Query: 292 LCSCEETRPLKCLVWDYDSRGKH----DFIG 318
E + L+ ++D D++ DF+G
Sbjct: 65 EYRFETVQKLRFGIYDIDNKTPELRDDDFLG 95
>gi|23397698 copine I isoform a [Homo sapiens]
Length = 537
Score = 454 bits (1169), Expect = e-128
Identities = 228/424 (53%), Positives = 297/424 (70%), Gaps = 6/424 (1%)
Query: 194 QIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPF 253
QIV+ + +T PL+LK G+ AG+ TITV A+++ N V + AR LD KD KSDPF
Sbjct: 103 QIVSSQVLTLPLMLKPGKPAGRGTITVSAQELKDNR-VVTMEVEARNLDKKDFLGKSDPF 161
Query: 254 LELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGK 313
LE +R D + LVYR+EV+KNNLNP W+ F V + C + P++ DYDS G
Sbjct: 162 LEFFRQGDGKW-HLVYRSEVIKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGS 220
Query: 314 HDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLD 373
HD IG F T+ ++Q A+++C++P+ +QK++SYKNSG + + + YSFLD
Sbjct: 221 HDLIGTFHTSLAQLQAV----PAEFECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLD 276
Query: 374 YIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRF 433
Y+MGGCQI+FTV +DFT SNGDP + SLHY++P NEYL AL SVG + QDYDSDK F
Sbjct: 277 YVMGGCQINFTVGVDFTGSNGDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLF 336
Query: 434 SALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIIS 493
A GFGA++PP ++VSH+FA+NFNP + C GIQG+V+AY+ LP+V+LYGPTN APII+
Sbjct: 337 PAFGFGAQVPPDWQVSHEFALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIIN 396
Query: 494 KVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFT 553
VAR AA G ASQY++LL+LTDG VTD+ TREA+VRAS LPMS+IIVGVG ADF
Sbjct: 397 HVARFAAQAAHQGTASQYFMLLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFE 456
Query: 554 DMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHR 613
M+ LD D G L + G+ A RDIVQFVP+R +NA ALA+ VLAEVP Q+V Y+ +
Sbjct: 457 AMEQLDADGGPLHTRSGQAAARDIVQFVPYRRFQNAPREALAQTVLAEVPTQLVSYFRAQ 516
Query: 614 GLPP 617
G P
Sbjct: 517 GWAP 520
Score = 97.8 bits (242), Expect = 3e-20
Identities = 50/103 (48%), Positives = 67/103 (65%), Gaps = 2/103 (1%)
Query: 18 APCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQG-QWVQVGRTEVVRSSLHPVFSKV 76
A C + V+L +SC HL+D+D +KSDP LLQ G W ++GRTE VR+ P FSK
Sbjct: 2 AHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSPEFSKT 61
Query: 77 FTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQ 119
++Y FE VQ+LRF +YD + ++DDFLGG EC+LGQ
Sbjct: 62 LQLEYRFETVQKLRFGIYDIDNKTP-ELRDDDFLGGAECSLGQ 103
Score = 40.8 bits (94), Expect = 0.004
Identities = 18/52 (34%), Positives = 33/52 (63%)
Query: 24 VELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVFSK 75
V + + R+L +D L KSDP + +Q G+W V R+EV++++L+P + +
Sbjct: 140 VTMEVEARNLDKKDFLGKSDPFLEFFRQGDGKWHLVYRSEVIKNNLNPTWKR 191
Score = 32.3 bits (72), Expect = 1.4
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
Query: 232 VELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSS 291
V+LS L DKD+ SKSDP L + + RTE V+N +P F +L
Sbjct: 8 VQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSP---EFSKTLQL 64
Query: 292 LCSCEETRPLKCLVWDYDSRGKH----DFIG 318
E + L+ ++D D++ DF+G
Sbjct: 65 EYRFETVQKLRFGIYDIDNKTPELRDDDFLG 95
>gi|23397696 copine I isoform a [Homo sapiens]
Length = 537
Score = 454 bits (1169), Expect = e-128
Identities = 228/424 (53%), Positives = 297/424 (70%), Gaps = 6/424 (1%)
Query: 194 QIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPF 253
QIV+ + +T PL+LK G+ AG+ TITV A+++ N V + AR LD KD KSDPF
Sbjct: 103 QIVSSQVLTLPLMLKPGKPAGRGTITVSAQELKDNR-VVTMEVEARNLDKKDFLGKSDPF 161
Query: 254 LELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGK 313
LE +R D + LVYR+EV+KNNLNP W+ F V + C + P++ DYDS G
Sbjct: 162 LEFFRQGDGKW-HLVYRSEVIKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGS 220
Query: 314 HDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLD 373
HD IG F T+ ++Q A+++C++P+ +QK++SYKNSG + + + YSFLD
Sbjct: 221 HDLIGTFHTSLAQLQAV----PAEFECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLD 276
Query: 374 YIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRF 433
Y+MGGCQI+FTV +DFT SNGDP + SLHY++P NEYL AL SVG + QDYDSDK F
Sbjct: 277 YVMGGCQINFTVGVDFTGSNGDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLF 336
Query: 434 SALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIIS 493
A GFGA++PP ++VSH+FA+NFNP + C GIQG+V+AY+ LP+V+LYGPTN APII+
Sbjct: 337 PAFGFGAQVPPDWQVSHEFALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIIN 396
Query: 494 KVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFT 553
VAR AA G ASQY++LL+LTDG VTD+ TREA+VRAS LPMS+IIVGVG ADF
Sbjct: 397 HVARFAAQAAHQGTASQYFMLLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFE 456
Query: 554 DMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHR 613
M+ LD D G L + G+ A RDIVQFVP+R +NA ALA+ VLAEVP Q+V Y+ +
Sbjct: 457 AMEQLDADGGPLHTRSGQAAARDIVQFVPYRRFQNAPREALAQTVLAEVPTQLVSYFRAQ 516
Query: 614 GLPP 617
G P
Sbjct: 517 GWAP 520
Score = 97.8 bits (242), Expect = 3e-20
Identities = 50/103 (48%), Positives = 67/103 (65%), Gaps = 2/103 (1%)
Query: 18 APCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQG-QWVQVGRTEVVRSSLHPVFSKV 76
A C + V+L +SC HL+D+D +KSDP LLQ G W ++GRTE VR+ P FSK
Sbjct: 2 AHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSPEFSKT 61
Query: 77 FTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQ 119
++Y FE VQ+LRF +YD + ++DDFLGG EC+LGQ
Sbjct: 62 LQLEYRFETVQKLRFGIYDIDNKTP-ELRDDDFLGGAECSLGQ 103
Score = 40.8 bits (94), Expect = 0.004
Identities = 18/52 (34%), Positives = 33/52 (63%)
Query: 24 VELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVFSK 75
V + + R+L +D L KSDP + +Q G+W V R+EV++++L+P + +
Sbjct: 140 VTMEVEARNLDKKDFLGKSDPFLEFFRQGDGKWHLVYRSEVIKNNLNPTWKR 191
Score = 32.3 bits (72), Expect = 1.4
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
Query: 232 VELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSS 291
V+LS L DKD+ SKSDP L + + RTE V+N +P F +L
Sbjct: 8 VQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSP---EFSKTLQL 64
Query: 292 LCSCEETRPLKCLVWDYDSRGKH----DFIG 318
E + L+ ++D D++ DF+G
Sbjct: 65 EYRFETVQKLRFGIYDIDNKTPELRDDDFLG 95
>gi|197333761 copine I isoform b [Homo sapiens]
Length = 542
Score = 454 bits (1169), Expect = e-128
Identities = 228/424 (53%), Positives = 297/424 (70%), Gaps = 6/424 (1%)
Query: 194 QIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPF 253
QIV+ + +T PL+LK G+ AG+ TITV A+++ N V + AR LD KD KSDPF
Sbjct: 108 QIVSSQVLTLPLMLKPGKPAGRGTITVSAQELKDNR-VVTMEVEARNLDKKDFLGKSDPF 166
Query: 254 LELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGK 313
LE +R D + LVYR+EV+KNNLNP W+ F V + C + P++ DYDS G
Sbjct: 167 LEFFRQGDGKW-HLVYRSEVIKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGS 225
Query: 314 HDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLD 373
HD IG F T+ ++Q A+++C++P+ +QK++SYKNSG + + + YSFLD
Sbjct: 226 HDLIGTFHTSLAQLQAV----PAEFECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLD 281
Query: 374 YIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRF 433
Y+MGGCQI+FTV +DFT SNGDP + SLHY++P NEYL AL SVG + QDYDSDK F
Sbjct: 282 YVMGGCQINFTVGVDFTGSNGDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLF 341
Query: 434 SALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIIS 493
A GFGA++PP ++VSH+FA+NFNP + C GIQG+V+AY+ LP+V+LYGPTN APII+
Sbjct: 342 PAFGFGAQVPPDWQVSHEFALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIIN 401
Query: 494 KVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFT 553
VAR AA G ASQY++LL+LTDG VTD+ TREA+VRAS LPMS+IIVGVG ADF
Sbjct: 402 HVARFAAQAAHQGTASQYFMLLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFE 461
Query: 554 DMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHR 613
M+ LD D G L + G+ A RDIVQFVP+R +NA ALA+ VLAEVP Q+V Y+ +
Sbjct: 462 AMEQLDADGGPLHTRSGQAAARDIVQFVPYRRFQNAPREALAQTVLAEVPTQLVSYFRAQ 521
Query: 614 GLPP 617
G P
Sbjct: 522 GWAP 525
Score = 97.8 bits (242), Expect = 3e-20
Identities = 50/103 (48%), Positives = 67/103 (65%), Gaps = 2/103 (1%)
Query: 18 APCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQG-QWVQVGRTEVVRSSLHPVFSKV 76
A C + V+L +SC HL+D+D +KSDP LLQ G W ++GRTE VR+ P FSK
Sbjct: 7 AHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSPEFSKT 66
Query: 77 FTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQ 119
++Y FE VQ+LRF +YD + ++DDFLGG EC+LGQ
Sbjct: 67 LQLEYRFETVQKLRFGIYDIDNKTP-ELRDDDFLGGAECSLGQ 108
Score = 40.8 bits (94), Expect = 0.004
Identities = 18/52 (34%), Positives = 33/52 (63%)
Query: 24 VELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVFSK 75
V + + R+L +D L KSDP + +Q G+W V R+EV++++L+P + +
Sbjct: 145 VTMEVEARNLDKKDFLGKSDPFLEFFRQGDGKWHLVYRSEVIKNNLNPTWKR 196
Score = 32.3 bits (72), Expect = 1.4
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
Query: 232 VELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSS 291
V+LS L DKD+ SKSDP L + + RTE V+N +P F +L
Sbjct: 13 VQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSP---EFSKTLQL 69
Query: 292 LCSCEETRPLKCLVWDYDSRGKH----DFIG 318
E + L+ ++D D++ DF+G
Sbjct: 70 EYRFETVQKLRFGIYDIDNKTPELRDDDFLG 100
>gi|25121972 copine VIII [Homo sapiens]
Length = 564
Score = 421 bits (1083), Expect = e-118
Identities = 228/427 (53%), Positives = 295/427 (69%), Gaps = 19/427 (4%)
Query: 200 KVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRV 259
++ +P++ G+ G TI + AE+++ V + F A KLD KD F KSDPFL YR
Sbjct: 130 RLEKPIVGIPGKKCG--TIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRS 187
Query: 260 NDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGE 319
N+D + ++TEVVKN LNPVW+AFK+S+ +LC+ + R +K V+D+D G HDFIGE
Sbjct: 188 NEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRDGSHDFIGE 247
Query: 320 FSTTFEEMQKAFEEGQAQ---WDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLDYIM 376
F+T++ E+ + GQ+Q ++ VNPK K K++ Y NSG V L SFLDYI
Sbjct: 248 FTTSYRELSR----GQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIK 303
Query: 377 GGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRFSAL 436
GG QI+FTVAIDFTASNG+P SLHY+NPYQ N Y AL +VGEI QDYDSDK F AL
Sbjct: 304 GGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQLNAYGMALKAVGEIVQDYDSDKMFPAL 363
Query: 437 GFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISKVA 496
GFGA++PP +SH+FA+N NP++ C+GI+GV+EAY L VQLYGPTN AP+I+ VA
Sbjct: 364 GFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVA 423
Query: 497 RVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFTDMQ 556
R A+ S SQY++LLI+TDGV++DMA T+E+IV AS+LPMSIIIVGVG A+F M
Sbjct: 424 RYAS---SVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMV 480
Query: 557 VLDGDDGVLRSPRGEPALRDIVQFVPFRELKN------ASPAALAKCVLAEVPKQVVEYY 610
LDGDD V S RG+ A RDIVQFVPFR+ + S A LAK VLAE+P+Q + Y
Sbjct: 481 ELDGDD-VRVSSRGKYAERDIVQFVPFRDYIDRSGNHILSMARLAKDVLAEIPEQFLSYM 539
Query: 611 SHRGLPP 617
RG+ P
Sbjct: 540 RARGIKP 546
Score = 92.8 bits (229), Expect = 9e-19
Identities = 47/101 (46%), Positives = 69/101 (68%), Gaps = 3/101 (2%)
Query: 21 ASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQG--QWVQVGRTEVVRSSLHPVFSKVFT 78
A++VE+ +SCR+LLDRD +KSDP L Q G +W + GRTEV+ ++L+P F + F
Sbjct: 23 ATRVEVSVSCRNLLDRDTFSKSDPICVLYVQGVGNKEWREFGRTEVIDNTLNPDFVRKFI 82
Query: 79 VDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQ 119
+DY+FEE + LRF++YD S + + DFLG + CTLG+
Sbjct: 83 LDYFFEERENLRFDLYDVDSKSP-NLSKHDFLGQVFCTLGE 122
Score = 47.8 bits (112), Expect = 3e-05
Identities = 38/101 (37%), Positives = 53/101 (52%), Gaps = 8/101 (7%)
Query: 232 VELSFRARKLDDKDLFSKSDPFLELY-RVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLS 290
VE+S R L D+D FSKSDP LY + ++ + RTEV+ N LNP + K L
Sbjct: 26 VEVSVSCRNLLDRDTFSKSDPICVLYVQGVGNKEWREFGRTEVIDNTLNPDF-VRKFILD 84
Query: 291 SLCSCEETRPLKCLVWDYDSR----GKHDFIGEFSTTFEEM 327
EE L+ ++D DS+ KHDF+G+ T E+
Sbjct: 85 YF--FEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEI 123
>gi|88703066 copine-like protein [Homo sapiens]
Length = 553
Score = 399 bits (1026), Expect = e-111
Identities = 223/440 (50%), Positives = 289/440 (65%), Gaps = 17/440 (3%)
Query: 200 KVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRV 259
+V R L G+ G TI + AE++S + A KLD KD F KSDPFL YR
Sbjct: 120 RVERTLTGVPGKKCG--TILLTAEELSNCRDIATMQLCANKLDKKDFFGKSDPFLVFYRS 177
Query: 260 NDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGE 319
N+D + ++TEVVKN LNPVW+ F + + +LC+ + R +K V+D+D G HDFIGE
Sbjct: 178 NEDGTFTICHKTEVVKNTLNPVWQPFSIPVRALCNGDYDRTVKIDVYDWDRDGSHDFIGE 237
Query: 320 FSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLDYIMGGC 379
F+T++ E+ KA + ++ +NP+ K K++ Y NSG V L ++F+DYI GG
Sbjct: 238 FTTSYRELSKAQNQFTV-YEVLNPRKKCKKKKYVNSGTVTLLSFSVDSEFTFVDYIKGGT 296
Query: 380 QIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRFSALGFG 439
Q++FTVAIDFTASNG+P SLHY++PYQ + Y AL +VGEI QDYDSDK F A GFG
Sbjct: 297 QLNFTVAIDFTASNGNPLQPTSLHYMSPYQLSAYAMALKAVGEIIQDYDSDKLFPAYGFG 356
Query: 440 ARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISKVARVA 499
A++PP+ +SH F +N N ED C GI+GV+E+Y L VQLYGPT AP+I++VAR A
Sbjct: 357 AKLPPEGRISHQFPLNNNDEDPNCAGIEGVLESYFQSLRTVQLYGPTYFAPVINQVAR-A 415
Query: 500 AAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFTDMQVLD 559
AA+ S G SQYY+LLI+TDGV++DM T+EAIV AS LPMSIIIVGVG A F M+ LD
Sbjct: 416 AAKISDG--SQYYVLLIITDGVISDMTQTKEAIVSASSLPMSIIIVGVGPAMFEAMEELD 473
Query: 560 GDDGVLRSPRGEPALRDIVQFVPFRELKN------ASPAALAKCVLAEVPKQVVEYYSHR 613
GDD V S RG A RDIVQFVPFR+ + S A LAK VLAE+P+Q++ Y R
Sbjct: 474 GDD-VRVSSRGRYAERDIVQFVPFRDYVDRSGNQVLSMARLAKDVLAEIPEQLLSYMRTR 532
Query: 614 GLPPRSLGVPAGEASPGCTP 633
+ PR P A+P P
Sbjct: 533 DIQPR----PPPPANPSPIP 548
Score = 88.6 bits (218), Expect = 2e-17
Identities = 45/101 (44%), Positives = 67/101 (66%), Gaps = 3/101 (2%)
Query: 21 ASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQG--QWVQVGRTEVVRSSLHPVFSKVFT 78
A+K+E+ +SCR+LLD D +KSDP V L Q++ +W + GRTEV+ ++L+P F + F
Sbjct: 13 ATKIEITVSCRNLLDLDTFSKSDPMVVLYTQSRASQEWREFGRTEVIDNTLNPDFVRKFV 72
Query: 79 VDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQ 119
+DY+FEE Q LRF+VY+ + S + DFLG LG+
Sbjct: 73 LDYFFEEKQNLRFDVYNVDSKTNIS-KPKDFLGQAFLALGE 112
Score = 39.7 bits (91), Expect = 0.009
Identities = 33/93 (35%), Positives = 48/93 (51%), Gaps = 8/93 (8%)
Query: 232 VELSFRARKLDDKDLFSKSDPFLELY-RVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLS 290
+E++ R L D D FSKSDP + LY + Q + RTEV+ N LNP + K L
Sbjct: 16 IEITVSCRNLLDLDTFSKSDPMVVLYTQSRASQEWREFGRTEVIDNTLNPDF-VRKFVLD 74
Query: 291 SLCSCEETRPLKCLVWDYDSRGK----HDFIGE 319
EE + L+ V++ DS+ DF+G+
Sbjct: 75 YF--FEEKQNLRFDVYNVDSKTNISKPKDFLGQ 105
>gi|47157322 protein kinase C, beta isoform 1 [Homo sapiens]
Length = 671
Score = 52.0 bits (123), Expect = 2e-06
Identities = 31/98 (31%), Positives = 52/98 (53%), Gaps = 5/98 (5%)
Query: 238 ARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVW-EAFKVSLSSLCSCE 296
A+ L D SDP+++L + D + + +T+ +K +LNP W E F+ L +
Sbjct: 180 AKNLVPMDPNGLSDPYVKLKLIPDPKS-ESKQKTKTIKCSLNPEWNETFRFQLKE---SD 235
Query: 297 ETRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQKAFEEG 334
+ R L +WD+D ++DF+G S E+QKA +G
Sbjct: 236 KDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKASVDG 273
>gi|20127450 protein kinase C, beta isoform 2 [Homo sapiens]
Length = 673
Score = 52.0 bits (123), Expect = 2e-06
Identities = 31/98 (31%), Positives = 52/98 (53%), Gaps = 5/98 (5%)
Query: 238 ARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVW-EAFKVSLSSLCSCE 296
A+ L D SDP+++L + D + + +T+ +K +LNP W E F+ L +
Sbjct: 180 AKNLVPMDPNGLSDPYVKLKLIPDPKS-ESKQKTKTIKCSLNPEWNETFRFQLKE---SD 235
Query: 297 ETRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQKAFEEG 334
+ R L +WD+D ++DF+G S E+QKA +G
Sbjct: 236 KDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKASVDG 273
>gi|13384594 protein kinase C, gamma [Homo sapiens]
Length = 697
Score = 49.7 bits (117), Expect = 8e-06
Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 3/97 (3%)
Query: 238 ARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEE 297
AR L D SDP+++L + D + L +T VK LNPVW + + +L +
Sbjct: 180 ARNLIPMDPNGLSDPYVKLKLIPDPRNLTK-QKTRTVKATLNPVWN--ETFVFNLKPGDV 236
Query: 298 TRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQKAFEEG 334
R L VWD+D ++DF+G S E+ KA +G
Sbjct: 237 ERRLSVEVWDWDRTSRNDFMGAMSFGVSELLKAPVDG 273
Score = 38.1 bits (87), Expect = 0.025
Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 7/98 (7%)
Query: 18 APCASKVELRLS-CRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVFSKV 76
AP A ++ + + R+L+ DP SDP V L + + +T V+++L+PV+++
Sbjct: 167 APTADEIHVTVGEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWNET 226
Query: 77 FTVDYYFEEVQ-RLRFEVYDTHGPSGFSCQEDDFLGGM 113
F + +V+ RL EV+D S +DF+G M
Sbjct: 227 FVFNLKPGDVERRLSVEVWDWDRTS-----RNDFMGAM 259
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 45.8 bits (107), Expect = 1e-04
Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 8/91 (8%)
Query: 237 RARKLDDKDLFSKSDPFLELY--------RVNDDQGLQLVYRTEVVKNNLNPVWEAFKVS 288
+AR L +D SDPF+++Y V + + RT+ V+ +LNP W +
Sbjct: 4715 QARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIY 4774
Query: 289 LSSLCSCEETRPLKCLVWDYDSRGKHDFIGE 319
S + + L+ VWDYD +DF+GE
Sbjct: 4775 KSISMEQLKKKTLEVTVWDYDRFSSNDFLGE 4805
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 45.8 bits (107), Expect = 1e-04
Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 8/91 (8%)
Query: 237 RARKLDDKDLFSKSDPFLELY--------RVNDDQGLQLVYRTEVVKNNLNPVWEAFKVS 288
+AR L +D SDPF+++Y V + + RT+ V+ +LNP W +
Sbjct: 4715 QARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIY 4774
Query: 289 LSSLCSCEETRPLKCLVWDYDSRGKHDFIGE 319
S + + L+ VWDYD +DF+GE
Sbjct: 4775 KSISMEQLKKKTLEVTVWDYDRFSSNDFLGE 4805
>gi|4506067 protein kinase C, alpha [Homo sapiens]
Length = 672
Score = 45.1 bits (105), Expect = 2e-04
Identities = 27/93 (29%), Positives = 48/93 (51%), Gaps = 5/93 (5%)
Query: 238 ARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVW-EAFKVSLSSLCSCE 296
A+ L D SDP+++L + D + + +T+ +++ LNP W E+F L +
Sbjct: 180 AKNLIPMDPNGLSDPYVKLKLIPDPKN-ESKQKTKTIRSTLNPQWNESFTFKLKP---SD 235
Query: 297 ETRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQK 329
+ R L +WD+D ++DF+G S E+ K
Sbjct: 236 KDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMK 268
Score = 32.0 bits (71), Expect = 1.8
Identities = 26/99 (26%), Positives = 48/99 (48%), Gaps = 10/99 (10%)
Query: 31 RHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVFSKVFTVDYY-FEEVQRL 89
++L+ DP SDP V L + +T+ +RS+L+P +++ FT ++ +RL
Sbjct: 181 KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRL 240
Query: 90 RFEVYDTHGPSGFSCQEDDFLG----GMECTLGQPAQKW 124
E++D + +DF+G G+ + PA W
Sbjct: 241 SVEIWDWDRTT-----RNDFMGSLSFGVSELMKMPASGW 274
>gi|209447073 synaptotagmin I [Homo sapiens]
Length = 422
Score = 43.9 bits (102), Expect = 5e-04
Identities = 31/96 (32%), Positives = 49/96 (51%), Gaps = 10/96 (10%)
Query: 228 NNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWE---A 284
NN + +A +L D+ SDP+++++ + D + + T+V + LNPV+
Sbjct: 156 NNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKK---FETKVHRKTLNPVFNEQFT 212
Query: 285 FKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGEF 320
FKV S L + L V+D+D KHD IGEF
Sbjct: 213 FKVPYSELGG----KTLVMAVYDFDRFSKHDIIGEF 244
Score = 37.7 bits (86), Expect = 0.032
Identities = 30/115 (26%), Positives = 56/115 (48%), Gaps = 21/115 (18%)
Query: 207 LKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQ 266
L++ AGK T+ ++ A+ L D+ SDP+++++ + + + L+
Sbjct: 281 LRYVPTAGKLTVVIL---------------EAKNLKKMDVGGLSDPYVKIHLMQNGKRLK 325
Query: 267 LVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVW--DYDSRGKHDFIGE 319
+T + KN LNP + S S E+ + ++ +V DYD GK+D IG+
Sbjct: 326 KK-KTTIKKNTLNPYYNE---SFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGK 376
Score = 33.5 bits (75), Expect = 0.61
Identities = 19/76 (25%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Query: 19 PCASKVELR-LSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVFSKVF 77
P A K+ + L ++L D SDP V + G+ ++ +T + +++L+P +++ F
Sbjct: 285 PTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESF 344
Query: 78 TVDYYFEEVQRLRFEV 93
+ + FE++Q+++ V
Sbjct: 345 SFEVPFEQIQKVQVVV 360
>gi|5032139 synaptotagmin I [Homo sapiens]
Length = 422
Score = 43.9 bits (102), Expect = 5e-04
Identities = 31/96 (32%), Positives = 49/96 (51%), Gaps = 10/96 (10%)
Query: 228 NNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWE---A 284
NN + +A +L D+ SDP+++++ + D + + T+V + LNPV+
Sbjct: 156 NNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKK---FETKVHRKTLNPVFNEQFT 212
Query: 285 FKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGEF 320
FKV S L + L V+D+D KHD IGEF
Sbjct: 213 FKVPYSELGG----KTLVMAVYDFDRFSKHDIIGEF 244
Score = 37.7 bits (86), Expect = 0.032
Identities = 30/115 (26%), Positives = 56/115 (48%), Gaps = 21/115 (18%)
Query: 207 LKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQ 266
L++ AGK T+ ++ A+ L D+ SDP+++++ + + + L+
Sbjct: 281 LRYVPTAGKLTVVIL---------------EAKNLKKMDVGGLSDPYVKIHLMQNGKRLK 325
Query: 267 LVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVW--DYDSRGKHDFIGE 319
+T + KN LNP + S S E+ + ++ +V DYD GK+D IG+
Sbjct: 326 KK-KTTIKKNTLNPYYNE---SFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGK 376
Score = 33.5 bits (75), Expect = 0.61
Identities = 19/76 (25%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Query: 19 PCASKVELR-LSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVFSKVF 77
P A K+ + L ++L D SDP V + G+ ++ +T + +++L+P +++ F
Sbjct: 285 PTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESF 344
Query: 78 TVDYYFEEVQRLRFEV 93
+ + FE++Q+++ V
Sbjct: 345 SFEVPFEQIQKVQVVV 360
>gi|209447070 synaptotagmin I [Homo sapiens]
Length = 422
Score = 43.9 bits (102), Expect = 5e-04
Identities = 31/96 (32%), Positives = 49/96 (51%), Gaps = 10/96 (10%)
Query: 228 NNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWE---A 284
NN + +A +L D+ SDP+++++ + D + + T+V + LNPV+
Sbjct: 156 NNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKK---FETKVHRKTLNPVFNEQFT 212
Query: 285 FKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGEF 320
FKV S L + L V+D+D KHD IGEF
Sbjct: 213 FKVPYSELGG----KTLVMAVYDFDRFSKHDIIGEF 244
Score = 37.7 bits (86), Expect = 0.032
Identities = 30/115 (26%), Positives = 56/115 (48%), Gaps = 21/115 (18%)
Query: 207 LKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQ 266
L++ AGK T+ ++ A+ L D+ SDP+++++ + + + L+
Sbjct: 281 LRYVPTAGKLTVVIL---------------EAKNLKKMDVGGLSDPYVKIHLMQNGKRLK 325
Query: 267 LVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVW--DYDSRGKHDFIGE 319
+T + KN LNP + S S E+ + ++ +V DYD GK+D IG+
Sbjct: 326 KK-KTTIKKNTLNPYYNE---SFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGK 376
Score = 33.5 bits (75), Expect = 0.61
Identities = 19/76 (25%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Query: 19 PCASKVELR-LSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVFSKVF 77
P A K+ + L ++L D SDP V + G+ ++ +T + +++L+P +++ F
Sbjct: 285 PTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESF 344
Query: 78 TVDYYFEEVQRLRFEV 93
+ + FE++Q+++ V
Sbjct: 345 SFEVPFEQIQKVQVVV 360
>gi|28376627 synaptotagmin IX [Homo sapiens]
Length = 491
Score = 42.7 bits (99), Expect = 0.001
Identities = 28/86 (32%), Positives = 46/86 (53%), Gaps = 10/86 (11%)
Query: 237 RARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEA---FKVSLSSLC 293
+A L KD SDP++++Y + D + ++T+V + LNPV++ F V + L
Sbjct: 243 KAVNLPAKDFSGTSDPYVKIYLLPDRK---TKHQTKVHRKTLNPVFDEVFLFPVPYNDL- 298
Query: 294 SCEETRPLKCLVWDYDSRGKHDFIGE 319
E R L V+D+D +HD IG+
Sbjct: 299 ---EARKLHFSVYDFDRFSRHDLIGQ 321
Score = 35.4 bits (80), Expect = 0.16
Identities = 31/109 (28%), Positives = 50/109 (45%), Gaps = 23/109 (21%)
Query: 213 AGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTE 272
AG+ TIT+I +AR L D+ SDP++++ + D + L+ +T
Sbjct: 366 AGRLTITII---------------KARNLKAMDITGASDPYVKVSLMCDGRRLK-KRKTS 409
Query: 273 VVKNNLNPVWE---AFKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIG 318
+N LNPV+ F V ++ + L V DYD G ++ IG
Sbjct: 410 TKRNTLNPVYNEAIVFDVPPENI----DQIHLSIAVMDYDRVGHNEIIG 454
Score = 31.6 bits (70), Expect = 2.3
Identities = 17/37 (45%), Positives = 24/37 (64%), Gaps = 2/37 (5%)
Query: 61 RTEVVRSSLHPVFSKV--FTVDYYFEEVQRLRFEVYD 95
+T+V R +L+PVF +V F V Y E ++L F VYD
Sbjct: 273 QTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYD 309
Score = 30.8 bits (68), Expect = 4.0
Identities = 17/76 (22%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Query: 19 PCASKVELRL-SCRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVFSKVF 77
P A ++ + + R+L D SDP V + G+ ++ +T R++L+PV+++
Sbjct: 364 PTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAI 423
Query: 78 TVDYYFEEVQRLRFEV 93
D E + ++ +
Sbjct: 424 VFDVPPENIDQIHLSI 439
>gi|238550198 synaptotagmin III [Homo sapiens]
Length = 590
Score = 42.0 bits (97), Expect = 0.002
Identities = 33/113 (29%), Positives = 54/113 (47%), Gaps = 10/113 (8%)
Query: 210 GRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVY 269
G A I+ + G++ V +A L KD SDP++++Y + D + +
Sbjct: 295 GTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKK---F 351
Query: 270 RTEVVKNNLNPVWEA---FKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGE 319
+T+V + LNPV+ F V L+ L R L V+D+D +HD IG+
Sbjct: 352 QTKVHRKTLNPVFNETFQFSVPLAELAQ----RKLHFSVYDFDRFSRHDLIGQ 400
>gi|238550196 synaptotagmin III [Homo sapiens]
Length = 590
Score = 42.0 bits (97), Expect = 0.002
Identities = 33/113 (29%), Positives = 54/113 (47%), Gaps = 10/113 (8%)
Query: 210 GRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVY 269
G A I+ + G++ V +A L KD SDP++++Y + D + +
Sbjct: 295 GTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKK---F 351
Query: 270 RTEVVKNNLNPVWEA---FKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGE 319
+T+V + LNPV+ F V L+ L R L V+D+D +HD IG+
Sbjct: 352 QTKVHRKTLNPVFNETFQFSVPLAELAQ----RKLHFSVYDFDRFSRHDLIGQ 400
>gi|14150054 synaptotagmin III [Homo sapiens]
Length = 590
Score = 42.0 bits (97), Expect = 0.002
Identities = 33/113 (29%), Positives = 54/113 (47%), Gaps = 10/113 (8%)
Query: 210 GRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVY 269
G A I+ + G++ V +A L KD SDP++++Y + D + +
Sbjct: 295 GTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKK---F 351
Query: 270 RTEVVKNNLNPVWEA---FKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGE 319
+T+V + LNPV+ F V L+ L R L V+D+D +HD IG+
Sbjct: 352 QTKVHRKTLNPVFNETFQFSVPLAELAQ----RKLHFSVYDFDRFSRHDLIGQ 400
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,618,443
Number of Sequences: 37866
Number of extensions: 1164952
Number of successful extensions: 2858
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 89
Number of HSP's that attempted gapping in prelim test: 2519
Number of HSP's gapped (non-prelim): 330
length of query: 633
length of database: 18,247,518
effective HSP length: 108
effective length of query: 525
effective length of database: 14,157,990
effective search space: 7432944750
effective search space used: 7432944750
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.