Search of human proteins with 74272287

Search of human proteins with 74272287

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|74272287 matrix metalloproteinase 9 preproprotein [Homo
sapiens]
         (707 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens]  1498   0.0  
gi|11342666 matrix metalloproteinase 2 isoform a preproprotein [...   617   e-176
gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]      601   e-172
gi|4505217 matrix metalloproteinase 3 preproprotein [Homo sapiens]    184   3e-46
gi|4505209 matrix metalloproteinase 13 preproprotein [Homo sapiens]   180   4e-45
gi|4505205 matrix metalloproteinase 10 preproprotein [Homo sapiens]   180   5e-45
gi|4505215 matrix metalloproteinase 1 isoform 1 preproprotein [H...   174   3e-43
gi|225543094 matrix metalloproteinase 1 isoform 2 [Homo sapiens]      161   2e-39
gi|73858572 matrix metalloproteinase 12 preproprotein [Homo sapi...   153   6e-37
gi|45359865 matrix metalloproteinase 20 preproprotein [Homo sapi...   152   1e-36
gi|58331148 matrix metalloproteinase 11 preproprotein [Homo sapi...   148   1e-35
gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens]      142   8e-34
gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens]      142   8e-34
gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens]      142   8e-34
gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens]      142   8e-34
gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens]      142   8e-34
gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens]      142   8e-34
gi|47132547 fibronectin 1 isoform 7 preproprotein [Homo sapiens]      142   8e-34
gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens]    142   1e-33
gi|5729929 matrix metalloproteinase 24 preproprotein [Homo sapiens]   142   1e-33
gi|4505219 matrix metalloproteinase 7 preproprotein [Homo sapiens]    141   2e-33
gi|4505211 matrix metalloproteinase 15 preproprotein [Homo sapiens]   141   2e-33
gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein ...   140   4e-33
gi|73808268 matrix metalloproteinase 27 [Homo sapiens]                140   5e-33
gi|4826834 matrix metalloproteinase 14 preproprotein [Homo sapiens]   135   1e-31
gi|11968059 matrix metalloproteinase 25 preproprotein [Homo sapi...   134   3e-31
gi|149999365 matrix metalloproteinase 16 isoform 2 preproprotein...   129   1e-29
gi|112382270 matrix metalloproteinase 17 preproprotein [Homo sap...   120   4e-27
gi|12408682 epididymal sperm binding protein 1 [Homo sapiens]         119   1e-26
gi|73808266 matrix metalloproteinase 26 preproprotein [Homo sapi...   112   2e-24

>gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens]
          Length = 707

 Score = 1498 bits (3878), Expect = 0.0
 Identities = 707/707 (100%), Positives = 707/707 (100%)

Query: 1   MSLWQPLVLVLLVLGCCFAAPRQRQSTLVLFPGDLRTNLTDRQLAEEYLYRYGYTRVAEM 60
           MSLWQPLVLVLLVLGCCFAAPRQRQSTLVLFPGDLRTNLTDRQLAEEYLYRYGYTRVAEM
Sbjct: 1   MSLWQPLVLVLLVLGCCFAAPRQRQSTLVLFPGDLRTNLTDRQLAEEYLYRYGYTRVAEM 60

Query: 61  RGESKSLGPALLLLQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFQTFEGDLKWHHHN 120
           RGESKSLGPALLLLQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFQTFEGDLKWHHHN
Sbjct: 61  RGESKSLGPALLLLQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFQTFEGDLKWHHHN 120

Query: 121 ITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYP 180
           ITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYP
Sbjct: 121 ITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYP 180

Query: 181 FDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGVVVPTRFGNADGAACHFPFIFEGRS 240
           FDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGVVVPTRFGNADGAACHFPFIFEGRS
Sbjct: 181 FDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGVVVPTRFGNADGAACHFPFIFEGRS 240

Query: 241 YSACTTDGRSDGLPWCSTTANYDTDDRFGFCPSERLYTQDGNADGKPCQFPFIFQGQSYS 300
           YSACTTDGRSDGLPWCSTTANYDTDDRFGFCPSERLYTQDGNADGKPCQFPFIFQGQSYS
Sbjct: 241 YSACTTDGRSDGLPWCSTTANYDTDDRFGFCPSERLYTQDGNADGKPCQFPFIFQGQSYS 300

Query: 301 ACTTDGRSDGYRWCATTANYDRDKLFGFCPTRADSTVMGGNSAGELCVFPFTFLGKEYST 360
           ACTTDGRSDGYRWCATTANYDRDKLFGFCPTRADSTVMGGNSAGELCVFPFTFLGKEYST
Sbjct: 301 ACTTDGRSDGYRWCATTANYDRDKLFGFCPTRADSTVMGGNSAGELCVFPFTFLGKEYST 360

Query: 361 CTSEGRGDGRLWCATTSNFDSDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMY 420
           CTSEGRGDGRLWCATTSNFDSDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMY
Sbjct: 361 CTSEGRGDGRLWCATTSNFDSDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMY 420

Query: 421 PMYRFTEGPPLHKDDVNGIRHLYGPRPEPEPRPPTTTTPQPTAPPTVCPTGPPTVHPSER 480
           PMYRFTEGPPLHKDDVNGIRHLYGPRPEPEPRPPTTTTPQPTAPPTVCPTGPPTVHPSER
Sbjct: 421 PMYRFTEGPPLHKDDVNGIRHLYGPRPEPEPRPPTTTTPQPTAPPTVCPTGPPTVHPSER 480

Query: 481 PTAGPTGPPSAGPTGPPTAGPSTATTVPLSPVDDACNVNIFDAIAEIGNQLYLFKDGKYW 540
           PTAGPTGPPSAGPTGPPTAGPSTATTVPLSPVDDACNVNIFDAIAEIGNQLYLFKDGKYW
Sbjct: 481 PTAGPTGPPSAGPTGPPTAGPSTATTVPLSPVDDACNVNIFDAIAEIGNQLYLFKDGKYW 540

Query: 541 RFSEGRGSRPQGPFLIADKWPALPRKLDSVFEERLSKKLFFFSGRQVWVYTGASVLGPRR 600
           RFSEGRGSRPQGPFLIADKWPALPRKLDSVFEERLSKKLFFFSGRQVWVYTGASVLGPRR
Sbjct: 541 RFSEGRGSRPQGPFLIADKWPALPRKLDSVFEERLSKKLFFFSGRQVWVYTGASVLGPRR 600

Query: 601 LDKLGLGADVAQVTGALRSGRGKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVPLD 660
           LDKLGLGADVAQVTGALRSGRGKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVPLD
Sbjct: 601 LDKLGLGADVAQVTGALRSGRGKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVPLD 660

Query: 661 THDVFQYREKAYFCQDRFYWRVSSRSELNQVDQVGYVTYDILQCPED 707
           THDVFQYREKAYFCQDRFYWRVSSRSELNQVDQVGYVTYDILQCPED
Sbjct: 661 THDVFQYREKAYFCQDRFYWRVSSRSELNQVDQVGYVTYDILQCPED 707


>gi|11342666 matrix metalloproteinase 2 isoform a preproprotein
           [Homo sapiens]
          Length = 660

 Score =  617 bits (1591), Expect = e-176
 Identities = 324/704 (46%), Positives = 430/704 (61%), Gaps = 70/704 (9%)

Query: 11  LLVLGCCFAAPRQRQSTLVLFPGDLRTNLTDRQLAEEYLYR-YGYTRVAEMRGESKSL-- 67
           L +LGC  +      S ++ FPGD+    TD++LA +YL   YG  +      ES +L  
Sbjct: 17  LCLLGCLLSHAAAAPSPIIKFPGDVAPK-TDKELAVQYLNTFYGCPK------ESCNLFV 69

Query: 68  -GPALLLLQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFQTFEGDLKWHHHNITYWIQ 126
               L  +QK   LP+TG+LD  T++ MR PRCG PD+  +  F    KW  + ITY I 
Sbjct: 70  LKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRII 129

Query: 127 NYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDG 186
            Y+ DL    +DDAFARAF +WS VTPL F+R++  +ADI+I FG  EHGDGYPFDGKDG
Sbjct: 130 GYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDG 189

Query: 187 LLAHAFPPGPGIQGDAHFDDDELWSLGKGVVVPTRFGNADGAACHFPFIFEGRSYSACTT 246
           LLAHAF PG G+ GD+HFDDDELW+LG+G VV  ++GNADG  C FPF+F G+ Y++CT 
Sbjct: 190 LLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTD 249

Query: 247 DGRSDGLPWCSTTANYDTDDRFGFCPSERLYTQDGNADGKPCQFPFIFQGQSYSACTTDG 306
            GRSDG  WCSTT N++ D ++GFCP E L+T  GNA+G+PC+FPF FQG SY +CTT+G
Sbjct: 250 TGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEG 309

Query: 307 RSDGYRWCATTANYDRDKLFGFCPTRADSTVMGGNSAGELCVFPFTFLGKEYSTCTSEGR 366
           R+DGYRWC TT +YDRDK +GFCP  A STV GGNS G  CVFPFTFLG +Y +CTS GR
Sbjct: 310 RTDGYRWCGTTEDYDRDKKYGFCPETAMSTV-GGNSEGAPCVFPFTFLGNKYESCTSAGR 368

Query: 367 GDGRLWCATTSNFDSDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFT 426
            DG++WCATT+N+D D+KWGFCPDQGYSLFLVAAHEFGHA+GL+HS  P ALM P+Y +T
Sbjct: 369 SDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYT 428

Query: 427 EGPPLHKDDVNGIRHLYGPRPEPEPRPPTTTTPQPTAPPTVCPTGPPTVHPSERPTAGPT 486
           +   L +DD+ GI+ LYG  P+ +                   TGP        PT GP 
Sbjct: 429 KNFRLSQDDIKGIQELYGASPDID-----------------LGTGP-------TPTLGPV 464

Query: 487 GPPSAGPTGPPTAGPSTATTVPLSPVDDACNVNI-FDAIAEIGNQLYLFKDGKYWRFSEG 545
            P                         + C  +I FD IA+I  +++ FKD   WR    
Sbjct: 465 TP-------------------------EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTP 499

Query: 546 RGSRPQGPFLIADKWPALPRKLDSVFEERLSKKLFFFSGRQVWVYTGASVLG--PRRLDK 603
           R  +P GP L+A  WP LP K+D+V+E    +K  FF+G + W+Y+ +++    P+ L  
Sbjct: 500 R-DKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTS 558

Query: 604 LGLGADVAQVTGALR-SGRGKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVP--LD 660
           LGL  DV +V  A   S   K  +F+G + WR++   + +DP     +   +  +P  LD
Sbjct: 559 LGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLD 618

Query: 661 THDVFQYREKAYFCQDRFYWRVSSRSELNQVDQVGYVTYDILQC 704
                Q    +YF +  +Y ++ ++S L  V + G +  D L C
Sbjct: 619 AVVDLQGGGHSYFFKGAYYLKLENQS-LKSV-KFGSIKSDWLGC 660


>gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]
          Length = 610

 Score =  601 bits (1550), Expect = e-172
 Identities = 305/644 (47%), Positives = 401/644 (62%), Gaps = 59/644 (9%)

Query: 67  LGPALLLLQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFQTFEGDLKWHHHNITYWIQ 126
           L   L  +QK   LP+TG+LD  T++ MR PRCG PD+  +  F    KW  + ITY I 
Sbjct: 20  LKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRII 79

Query: 127 NYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDG 186
            Y+ DL    +DDAFARAF +WS VTPL F+R++  +ADI+I FG  EHGDGYPFDGKDG
Sbjct: 80  GYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDG 139

Query: 187 LLAHAFPPGPGIQGDAHFDDDELWSLGKGVVVPTRFGNADGAACHFPFIFEGRSYSACTT 246
           LLAHAF PG G+ GD+HFDDDELW+LG+G VV  ++GNADG  C FPF+F G+ Y++CT 
Sbjct: 140 LLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTD 199

Query: 247 DGRSDGLPWCSTTANYDTDDRFGFCPSERLYTQDGNADGKPCQFPFIFQGQSYSACTTDG 306
            GRSDG  WCSTT N++ D ++GFCP E L+T  GNA+G+PC+FPF FQG SY +CTT+G
Sbjct: 200 TGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEG 259

Query: 307 RSDGYRWCATTANYDRDKLFGFCPTRADSTVMGGNSAGELCVFPFTFLGKEYSTCTSEGR 366
           R+DGYRWC TT +YDRDK +GFCP  A STV GGNS G  CVFPFTFLG +Y +CTS GR
Sbjct: 260 RTDGYRWCGTTEDYDRDKKYGFCPETAMSTV-GGNSEGAPCVFPFTFLGNKYESCTSAGR 318

Query: 367 GDGRLWCATTSNFDSDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFT 426
            DG++WCATT+N+D D+KWGFCPDQGYSLFLVAAHEFGHA+GL+HS  P ALM P+Y +T
Sbjct: 319 SDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYT 378

Query: 427 EGPPLHKDDVNGIRHLYGPRPEPEPRPPTTTTPQPTAPPTVCPTGPPTVHPSERPTAGPT 486
           +   L +DD+ GI+ LYG  P+ +                   TGP        PT GP 
Sbjct: 379 KNFRLSQDDIKGIQELYGASPDID-----------------LGTGP-------TPTLGPV 414

Query: 487 GPPSAGPTGPPTAGPSTATTVPLSPVDDACNVNI-FDAIAEIGNQLYLFKDGKYWRFSEG 545
            P                         + C  +I FD IA+I  +++ FKD   WR    
Sbjct: 415 TP-------------------------EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTP 449

Query: 546 RGSRPQGPFLIADKWPALPRKLDSVFEERLSKKLFFFSGRQVWVYTGASVLG--PRRLDK 603
           R  +P GP L+A  WP LP K+D+V+E    +K  FF+G + W+Y+ +++    P+ L  
Sbjct: 450 R-DKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTS 508

Query: 604 LGLGADVAQVTGALR-SGRGKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVP--LD 660
           LGL  DV +V  A   S   K  +F+G + WR++   + +DP     +   +  +P  LD
Sbjct: 509 LGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLD 568

Query: 661 THDVFQYREKAYFCQDRFYWRVSSRSELNQVDQVGYVTYDILQC 704
                Q    +YF +  +Y ++ ++S L  V + G +  D L C
Sbjct: 569 AVVDLQGGGHSYFFKGAYYLKLENQS-LKSV-KFGSIKSDWLGC 610


>gi|4505217 matrix metalloproteinase 3 preproprotein [Homo sapiens]
          Length = 477

 Score =  184 bits (466), Expect = 3e-46
 Identities = 98/209 (46%), Positives = 126/209 (60%), Gaps = 15/209 (7%)

Query: 8   VLVLLVLGCCFAAPRQRQSTLVLFPGDLRTNLTDRQLAEEYLYRYGYTRVAEMRG--ESK 65
           +L+LL +  C A P           G  R   T   L ++YL  Y Y    +++     K
Sbjct: 6   ILLLLCVAVCSAYP---------LDGAARGEDTSMNLVQKYLENY-YDLKKDVKQFVRRK 55

Query: 66  SLGPALLLL---QKQLSLPETGELDSATLKAMRTPRCGVPDLGRFQTFEGDLKWHHHNIT 122
             GP +  +   QK L L  TG+LDS TL+ MR PRCGVPD+G F+TF G  KW   ++T
Sbjct: 56  DSGPVVKKIREMQKFLGLEVTGKLDSDTLEVMRKPRCGVPDVGHFRTFPGIPKWRKTHLT 115

Query: 123 YWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFD 182
           Y I NY+ DLP+  +D A  +A  +W  VTPLTF+R+Y  +ADI+I F V EHGD YPFD
Sbjct: 116 YRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFD 175

Query: 183 GKDGLLAHAFPPGPGIQGDAHFDDDELWS 211
           G   +LAHA+ PGPGI GDAHFDDDE W+
Sbjct: 176 GPGNVLAHAYAPGPGINGDAHFDDDEQWT 204



 Score =  130 bits (328), Expect = 3e-30
 Identities = 95/307 (30%), Positives = 135/307 (43%), Gaps = 62/307 (20%)

Query: 377 SNFDSDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMY-------RFTEGP 429
           ++FD D++W      G +LFLVAAHE GH+LGL HS+  EALMYP+Y       RF    
Sbjct: 195 AHFDDDEQWTK-DTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFR--- 250

Query: 430 PLHKDDVNGIRHLYGPRPEPEPRPPTTTTPQPTAPPTVCPTGPPTVHPSERPTAGPTGPP 489
            L +DD+NGI+ LYGP P+    P   T P P  P T                       
Sbjct: 251 -LSQDDINGIQSLYGPPPDSPETPLVPTEPVPPEPGT----------------------- 286

Query: 490 SAGPTGPPTAGPSTATTVPLSPVDDACNVNIFDAIAEIGNQLYLFKDGKYWRFSEGRGSR 549
                 P    P+ +                FDA++ +  ++ +FKD  +WR S  R   
Sbjct: 287 ------PANCDPALS----------------FDAVSTLRGEILIFKDRHFWRKSL-RKLE 323

Query: 550 PQGPFLIADKWPALPRKLDSVFEERLSKKLFFFSGRQVWVYTGASVLG--PRRLDKLGLG 607
           P+   LI+  WP+LP  +D+ +E      +F F G Q W   G  V    PR +  LG  
Sbjct: 324 PE-LHLISSFWPSLPSGVDAAYEVTSKDLVFIFKGNQFWAIRGNEVRAGYPRGIHTLGFP 382

Query: 608 ADVAQVTGALR-SGRGKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVPLDTHDVFQ 666
             V ++  A+    + K   F   + WRFD K   ++P    ++   FPG+      VF+
Sbjct: 383 PTVRKIDAAISDKEKNKTYFFVEDKYWRFDEKRNSMEPGFPKQIAEDFPGIDSKIDAVFE 442

Query: 667 YREKAYF 673
                YF
Sbjct: 443 EFGFFYF 449


>gi|4505209 matrix metalloproteinase 13 preproprotein [Homo sapiens]
          Length = 471

 Score =  180 bits (457), Expect = 4e-45
 Identities = 101/217 (46%), Positives = 130/217 (59%), Gaps = 16/217 (7%)

Query: 41  DRQLAEEYLYRYGY-TRVAEMRGES--KSLGPALLLLQKQLSLPETGELDSATLKAMRTP 97
           D Q AE YL  Y + T +A +  E+   S+   L  +Q    L  TG+LD  TL  M+ P
Sbjct: 35  DLQFAERYLRSYYHPTNLAGILKENAASSMTERLREMQSFFGLEVTGKLDDNTLDVMKKP 94

Query: 98  RCGVPDLGRFQTFEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFT 157
           RCGVPD+G +  F   LKW   N+TY I NY+ D+  + ++ AF +AF +WS VTPL FT
Sbjct: 95  RCGVPDVGEYNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFT 154

Query: 158 RVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELW-SLGKG- 215
           R++   ADI+I FG+ EHGD YPFDG  GLLAHAFPPGP   GDAHFDDDE W S  KG 
Sbjct: 155 RLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGY 214

Query: 216 ---VVVPTRFGNA-------DGAACHFP-FIFEGRSY 241
              +V    FG++       D  A  FP + + G+S+
Sbjct: 215 NLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSH 251



 Score =  139 bits (350), Expect = 9e-33
 Identities = 94/302 (31%), Positives = 136/302 (45%), Gaps = 62/302 (20%)

Query: 377 SNFDSDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTEGPP--LHKD 434
           ++FD D+ W     +GY+LFLVAAHEFGH+LGLDHS  P ALM+P+Y +T      L  D
Sbjct: 199 AHFDDDETWT-SSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDD 257

Query: 435 DVNGIRHLYGPRPEPEPRPPTTTTPQPTAPPTVCPTGPPTVHPSERPTAGPTGPPSAGPT 494
           DV GI+ LYGP  E          P P  P T                            
Sbjct: 258 DVQGIQSLYGPGDED---------PNPKHPKT---------------------------- 280

Query: 495 GPPTAGPSTATTVPLSPVDDACNVNIFDAIAEIGNQLYLFKDGKYWRFSEGRGSRPQGPF 554
            P    PS +                 DAI  +  +  +FKD  +WR    +       F
Sbjct: 281 -PDKCDPSLS----------------LDAITSLRGETMIFKDRFFWRLHPQQVDAEL--F 321

Query: 555 LIADKWPALPRKLDSVFEERLSKKLFFFSGRQVWVYTGASVLG--PRRLDKLGLGADVAQ 612
           L    WP LP ++D+ +E      +F F GR+ W   G  +L   P+++ +LGL  +V +
Sbjct: 322 LTKSFWPELPNRIDAAYEHPSHDLIFIFRGRKFWALNGYDILEGYPKKISELGLPKEVKK 381

Query: 613 VTGALR-SGRGKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVPLDTHDVFQYREKA 671
           ++ A+     GK LLFSG ++WR+D    ++D      ++  FPG+      V++     
Sbjct: 382 ISAAVHFEDTGKTLLFSGNQVWRYDDTNHIMDKDYPRLIEEDFPGIGDKVDAVYEKNGYI 441

Query: 672 YF 673
           YF
Sbjct: 442 YF 443


>gi|4505205 matrix metalloproteinase 10 preproprotein [Homo sapiens]
          Length = 476

 Score =  180 bits (456), Expect = 5e-45
 Identities = 95/207 (45%), Positives = 126/207 (60%), Gaps = 14/207 (6%)

Query: 9   LVLLVLGCCFAAPRQRQSTLVLFPGDLRTNLTDRQLAEEYLYRYGYTRVAEM----RGES 64
           LVLL L  C A P           G  +   +++ LA++YL +Y Y    ++    R +S
Sbjct: 7   LVLLCLPVCSAYP---------LSGAAKEEDSNKDLAQQYLEKY-YNLEKDVKQFRRKDS 56

Query: 65  KSLGPALLLLQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFQTFEGDLKWHHHNITYW 124
             +   +  +QK L L  TG+LD+ TL+ MR PRCGVPD+G F +F G  KW   ++TY 
Sbjct: 57  NLIVKKIQGMQKFLGLEVTGKLDTDTLEVMRKPRCGVPDVGHFSSFPGMPKWRKTHLTYR 116

Query: 125 IQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGK 184
           I NY+ DLPR  +D A  +A  +W  VTPLTF+R+Y  +ADI+I F V EHGD Y FDG 
Sbjct: 117 IVNYTPDLPRDAVDSAIEKALKVWEEVTPLTFSRLYEGEADIMISFAVKEHGDFYSFDGP 176

Query: 185 DGLLAHAFPPGPGIQGDAHFDDDELWS 211
              LAHA+PPGPG+ GD HFDDDE W+
Sbjct: 177 GHSLAHAYPPGPGLYGDIHFDDDEKWT 203



 Score =  126 bits (317), Expect = 6e-29
 Identities = 100/303 (33%), Positives = 136/303 (44%), Gaps = 56/303 (18%)

Query: 378 NFDSDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYR-FTEGPP--LHKD 434
           +FD D+KW      G +LFLVAAHE GH+LGL HS+  EALMYP+Y  FTE     L +D
Sbjct: 195 HFDDDEKWTE-DASGTNLFLVAAHELGHSLGLFHSANTEALMYPLYNSFTELAQFRLSQD 253

Query: 435 DVNGIRHLYGPRPEPEPRPPTTTTPQPTAPPTVCPTGPPTVHPSERPTAGPTGPPSAGPT 494
           DVNGI+ LYG        PP  +T +P  P    P+G      SE P             
Sbjct: 254 DVNGIQSLYG--------PPPASTEEPLVPTKSVPSG------SEMP------------- 286

Query: 495 GPPTAGPSTATTVPLSPVDDACNVNIFDAIAEIGNQLYLFKDGKYWRFSEGRGSRPQGPF 554
                          +  D A +   FDAI+ +  +   FKD  +WR S      P+  F
Sbjct: 287 ---------------AKCDPALS---FDAISTLRGEYLFFKDRYFWRRSHW---NPEPEF 325

Query: 555 -LIADKWPALPRKLDSVFEERLSKKLFFFSGRQVWVYTGASVLG--PRRLDKLGLGADVA 611
            LI+  WP+LP  LD+ +E      +F F G + W   G  V    PR +  LG    + 
Sbjct: 326 HLISAFWPSLPSYLDAAYEVNSRDTVFIFKGNEFWAIRGNEVQAGYPRGIHTLGFPPTIR 385

Query: 612 QVTGALR-SGRGKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVPLDTHDVFQYREK 670
           ++  A+    + K   F+  + WRFD  +Q ++      +   FPGV      V Q    
Sbjct: 386 KIDAAVSDKEKKKTYFFAADKYWRFDENSQSMEQGFPRLIADDFPGVEPKVDAVLQAFGF 445

Query: 671 AYF 673
            YF
Sbjct: 446 FYF 448


>gi|4505215 matrix metalloproteinase 1 isoform 1 preproprotein [Homo
           sapiens]
          Length = 469

 Score =  174 bits (440), Expect = 3e-43
 Identities = 90/185 (48%), Positives = 114/185 (61%), Gaps = 4/185 (2%)

Query: 31  FPGDLRTNLTDRQLAEEYLYRY----GYTRVAEMRGESKSLGPALLLLQKQLSLPETGEL 86
           FP  L T   D  L ++YL +Y       R  E R  S  +   L  +Q+   L  TG+ 
Sbjct: 20  FPATLETQEQDVDLVQKYLEKYYNLKNDGRQVEKRRNSGPVVEKLKQMQEFFGLKVTGKP 79

Query: 87  DSATLKAMRTPRCGVPDLGRFQTFEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFA 146
           D+ TLK M+ PRCGVPD+ +F   EG+ +W   ++TY I+NY+ DLPRA +D A  +AF 
Sbjct: 80  DAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIENYTPDLPRADVDHAIEKAFQ 139

Query: 147 LWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDD 206
           LWS VTPLTFT+V    ADI+I F   +H D  PFDG  G LAHAF PGPGI GDAHFD+
Sbjct: 140 LWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGNLAHAFQPGPGIGGDAHFDE 199

Query: 207 DELWS 211
           DE W+
Sbjct: 200 DERWT 204



 Score =  100 bits (249), Expect = 5e-21
 Identities = 89/314 (28%), Positives = 129/314 (41%), Gaps = 81/314 (25%)

Query: 377 SNFDSDKKW--GFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTEGPPLHKD 434
           ++FD D++W   F   + Y+L  VAAHE GH+LGL HS+   ALMYP Y F+    L +D
Sbjct: 195 AHFDEDERWTNNF---REYNLHRVAAHELGHSLGLSHSTDIGALMYPSYTFSGDVQLAQD 251

Query: 435 DVNGIRHLYGPRPEPEPRPPTTTTPQPTAPPTVCPTGPPTVHPSERPTAGPTGPPSAGPT 494
           D++GI+ +YG    P                 V P GP T                    
Sbjct: 252 DIDGIQAIYGRSQNP-----------------VQPIGPQT-------------------- 274

Query: 495 GPPTAGPSTATTVPLSPVDDACNVNIFDAIAEIGNQLYLFKDGKYWRFSEGRGSRPQGPF 554
             P A  S  T               FDAI  I  ++  FKD  Y R      + P  P 
Sbjct: 275 --PKACDSKLT---------------FDAITTIRGEVMFFKDRFYMR------TNPFYPE 311

Query: 555 L----IADKWPALPRKLDSVFEERLSKKLFFFSGRQVWVYTGASVLG--PRRL-DKLGLG 607
           +    I+  WP LP  L++ +E     ++ FF G + W   G +VL   P+ +    G  
Sbjct: 312 VELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGYPKDIYSSFGFP 371

Query: 608 ADVAQVTGAL-RSGRGKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVPLDTHDVFQ 666
             V  +  AL     GK   F   + WR+D   + +DP     +   FPG+         
Sbjct: 372 RTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFPGI--------G 423

Query: 667 YREKAYFCQDRFYW 680
           ++  A F +D F++
Sbjct: 424 HKVDAVFMKDGFFY 437


>gi|225543094 matrix metalloproteinase 1 isoform 2 [Homo sapiens]
          Length = 403

 Score =  161 bits (408), Expect = 2e-39
 Identities = 76/138 (55%), Positives = 96/138 (69%)

Query: 74  LQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFQTFEGDLKWHHHNITYWIQNYSEDLP 133
           +Q+   L  TG+ D+ TLK M+ PRCGVPD+ +F   EG+ +W   ++TY I+NY+ DLP
Sbjct: 1   MQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIENYTPDLP 60

Query: 134 RAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFP 193
           RA +D A  +AF LWS VTPLTFT+V    ADI+I F   +H D  PFDG  G LAHAF 
Sbjct: 61  RADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGNLAHAFQ 120

Query: 194 PGPGIQGDAHFDDDELWS 211
           PGPGI GDAHFD+DE W+
Sbjct: 121 PGPGIGGDAHFDEDERWT 138



 Score =  100 bits (249), Expect = 5e-21
 Identities = 89/314 (28%), Positives = 129/314 (41%), Gaps = 81/314 (25%)

Query: 377 SNFDSDKKW--GFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTEGPPLHKD 434
           ++FD D++W   F   + Y+L  VAAHE GH+LGL HS+   ALMYP Y F+    L +D
Sbjct: 129 AHFDEDERWTNNF---REYNLHRVAAHELGHSLGLSHSTDIGALMYPSYTFSGDVQLAQD 185

Query: 435 DVNGIRHLYGPRPEPEPRPPTTTTPQPTAPPTVCPTGPPTVHPSERPTAGPTGPPSAGPT 494
           D++GI+ +YG    P                 V P GP T                    
Sbjct: 186 DIDGIQAIYGRSQNP-----------------VQPIGPQT-------------------- 208

Query: 495 GPPTAGPSTATTVPLSPVDDACNVNIFDAIAEIGNQLYLFKDGKYWRFSEGRGSRPQGPF 554
             P A  S  T               FDAI  I  ++  FKD  Y R      + P  P 
Sbjct: 209 --PKACDSKLT---------------FDAITTIRGEVMFFKDRFYMR------TNPFYPE 245

Query: 555 L----IADKWPALPRKLDSVFEERLSKKLFFFSGRQVWVYTGASVLG--PRRL-DKLGLG 607
           +    I+  WP LP  L++ +E     ++ FF G + W   G +VL   P+ +    G  
Sbjct: 246 VELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGYPKDIYSSFGFP 305

Query: 608 ADVAQVTGAL-RSGRGKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVPLDTHDVFQ 666
             V  +  AL     GK   F   + WR+D   + +DP     +   FPG+         
Sbjct: 306 RTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFPGI--------G 357

Query: 667 YREKAYFCQDRFYW 680
           ++  A F +D F++
Sbjct: 358 HKVDAVFMKDGFFY 371


>gi|73858572 matrix metalloproteinase 12 preproprotein [Homo
           sapiens]
          Length = 470

 Score =  153 bits (386), Expect = 6e-37
 Identities = 76/175 (43%), Positives = 104/175 (59%)

Query: 41  DRQLAEEYLYRYGYTRVAEMRGESKSLGPALLLLQKQLSLPETGELDSATLKAMRTPRCG 100
           +R L + Y        V +M+     +   +  +Q  L L  TG+LD++TL+ M  PRCG
Sbjct: 34  ERYLEKFYGLEINKLPVTKMKYSGNLMKEKIQEMQHFLGLKVTGQLDTSTLEMMHAPRCG 93

Query: 101 VPDLGRFQTFEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVY 160
           VPD+  F+   G   W  H ITY I NY+ D+ R  +D A  +AF +WS VTPL F+++ 
Sbjct: 94  VPDVHHFREMPGGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKIN 153

Query: 161 SRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKG 215
           +  ADI++ F    HGD + FDGK G+LAHAF PG GI GDAHFD+DE W+   G
Sbjct: 154 TGMADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSG 208



 Score =  105 bits (263), Expect = 1e-22
 Identities = 80/305 (26%), Positives = 131/305 (42%), Gaps = 66/305 (21%)

Query: 377 SNFDSDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTEGPP--LHKD 434
           ++FD D+ W      G +LFL A HE GH+LGL HSS P+A+M+P Y++ +     L  D
Sbjct: 195 AHFDEDEFWT-THSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSAD 253

Query: 435 DVNGIRHLYGPRPEPEPRPPTTTTPQPTAPPTVCPTGPPTVHPSERPTAGPTGPPSAGPT 494
           D+ GI+ LYG  P+   R P     +P                                 
Sbjct: 254 DIRGIQSLYGD-PKENQRLPNPDNSEPA-------------------------------- 280

Query: 495 GPPTAGPSTATTVPLSPVDDACNVNI-FDAIAEIGNQLYLFKDGKYW-RFSEGRGSRPQG 552
                                C+ N+ FDA+  +GN+++ FKD  +W + SE    RP+ 
Sbjct: 281 --------------------LCDPNLSFDAVTTVGNKIFFFKDRFFWLKVSE----RPKT 316

Query: 553 PF-LIADKWPALPRKLDSVFEERLSKKLFFFSGRQVWVYTG--ASVLGPRRLDKLGLGAD 609
              LI+  WP LP  +++ +E     ++F F   + W+ +        P+ +   G    
Sbjct: 317 SVNLISSLWPTLPSGIEAAYEIEARNQVFLFKDDKYWLISNLRPEPNYPKSIHSFGFPNF 376

Query: 610 VAQVTGALRSGR-GKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVPLDTHDVFQYR 668
           V ++  A+ + R  +   F   + WR+D + QM+DP     + + F G+      VF  +
Sbjct: 377 VKKIDAAVFNPRFYRTYFFVDNQYWRYDERRQMMDPGYPKLITKNFQGIGPKIDAVFYSK 436

Query: 669 EKAYF 673
            K Y+
Sbjct: 437 NKYYY 441


>gi|45359865 matrix metalloproteinase 20 preproprotein [Homo
           sapiens]
          Length = 483

 Score =  152 bits (384), Expect = 1e-36
 Identities = 86/232 (37%), Positives = 121/232 (52%), Gaps = 17/232 (7%)

Query: 8   VLVLLVLGCCFAAPRQRQSTLVLFPGDLRTNLTDRQLAEEYLYRYGYTRVAEMRGESKSL 67
           V +++ L    AAP    S +   P   R N    +LA+ YL +Y   +     GE  + 
Sbjct: 11  VFLIMALKFSTAAP----SLVAASPRTWRNNY---RLAQAYLDKYYTNKEGHQIGEMVAR 63

Query: 68  GPALLL-----LQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFQTFEGDLKWHHHNIT 122
           G   ++     LQ    L  TG+LD  T+  ++ PRCGVPD+  ++ F G+ KW  + +T
Sbjct: 64  GSNSMIRKIKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANYRLFPGEPKWKKNTLT 123

Query: 123 YWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFD 182
           Y I  Y+  +    +D A   A   WS+  PL+F R+ S +ADI+I F   +HGD YPFD
Sbjct: 124 YRISKYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHGDSYPFD 183

Query: 183 GKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKG-----VVVPTRFGNADGAA 229
           G  G LAHAF PG G+ GD HFD+ E W++G        V    FG+A G A
Sbjct: 184 GPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGTNGFNLFTVAAHEFGHALGLA 235



 Score =  110 bits (276), Expect = 3e-24
 Identities = 89/289 (30%), Positives = 127/289 (43%), Gaps = 60/289 (20%)

Query: 377 SNFDSDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTE--GPPLHKD 434
           ++FD+ +KW    + G++LF VAAHEFGHALGL HS+ P ALMYP Y++    G  L KD
Sbjct: 203 THFDNAEKWTMGTN-GFNLFTVAAHEFGHALGLAHSTDPSALMYPTYKYKNPYGFHLPKD 261

Query: 435 DVNGIRHLYGPRPEPEPRPPTTTTPQPTAPPTVCPTGPPTVHPSERPTAGPTGPPSAGPT 494
           DV GI+ LYGPR             +PT P            P  +P+            
Sbjct: 262 DVKGIQALYGPR--------KVFLGKPTLPHA----------PHHKPS------------ 291

Query: 495 GPPTAGPSTATTVPLSPVDDAC-NVNIFDAIAEIGNQLYLFKDGKYWR--FSEGRGSRPQ 551
                            + D C + + FDA+  +G +L LFKD  +WR       G RP 
Sbjct: 292 -----------------IPDLCDSSSSFDAVTMLGKELLLFKDRIFWRRQVHLRTGIRPS 334

Query: 552 GPFLIADKWPALPRKLDSVFEERLSKKLFFFSGRQVWVYTGASVLG-PRRLDKLGLGADV 610
               I   +P L   +D+ +E       +FF G   W+  G  + G PR +   G    V
Sbjct: 335 ---TITSSFPQLMSNVDAAYEVAERGTAYFFKGPHYWITRGFQMQGPPRTIYDFGFPRHV 391

Query: 611 AQVTGA--LRSGRGKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGV 657
            Q+  A  LR  + K L F G   + +D + + ++       +  F GV
Sbjct: 392 QQIDAAVYLREPQ-KTLFFVGDEYYSYDERKRKMEKDYPKNTEEEFSGV 439


>gi|58331148 matrix metalloproteinase 11 preproprotein [Homo
           sapiens]
          Length = 488

 Score =  148 bits (374), Expect = 1e-35
 Identities = 108/311 (34%), Positives = 140/311 (45%), Gaps = 52/311 (16%)

Query: 378 NFDSDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTEGPPLHKDDVN 437
           +FD D+ W    DQG  L  VAAHEFGH LGL H++  +ALM   Y F     L  DD  
Sbjct: 192 HFDYDETWTIGDDQGTDLLQVAAHEFGHVLGLQHTTAAKALMSAFYTFRYPLSLSPDDCR 251

Query: 438 GIRHLYGPRPEPEPRPPTTTTPQPTAPPTVCPTGPPTVHPSERPTAGPTGPPSAGPTGPP 497
           G++HLYG     +P P  T                     S  P  GP            
Sbjct: 252 GVQHLYG-----QPWPTVT---------------------SRTPALGPQ----------- 274

Query: 498 TAGPSTATTVPLSP--VDDACNVNIFDAIAEIGNQLYLFKDGKYWRFSEGRGSRPQGPFL 555
            AG  T    PL P    DAC  + FDA++ I  +L+ FK G  WR   G+  +P  P L
Sbjct: 275 -AGIDTNEIAPLEPDAPPDACEAS-FDAVSTIRGELFFFKAGFVWRLRGGQ-LQPGYPAL 331

Query: 556 IADKWPALPRKLDSVFEERLSKKLFFFSGRQVWVYTGAS-VLGPRRLDKLGLGADVAQVT 614
            +  W  LP  +D+ FE+     ++FF G Q WVY G   VLGP  L +LGL        
Sbjct: 332 ASRHWQGLPSPVDAAFED-AQGHIWFFQGAQYWVYDGEKPVLGPAPLTELGLVRFPVHAA 390

Query: 615 GALRSGRGKMLLFSGRRLWRFDVKAQMVD---PRSASEVDRMFPGVPLDTHDVFQYRE-K 670
                 + K+  F GR  WRF    + VD   PR A++    + GVP +    FQ  +  
Sbjct: 391 LVWGPEKNKIYFFRGRDYWRFHPSTRRVDSPVPRRATD----WRGVPSEIDAAFQDADGY 446

Query: 671 AYFCQDRFYWR 681
           AYF + R YW+
Sbjct: 447 AYFLRGRLYWK 457



 Score =  102 bits (255), Expect = 9e-22
 Identities = 56/131 (42%), Positives = 71/131 (54%), Gaps = 12/131 (9%)

Query: 93  AMRTPRCGVPDLG----------RFQTFEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFA 142
           ++R PRCGVPD            RF    G  +W   ++TY I  +   L +  +    A
Sbjct: 74  SLRPPRCGVPDPSDGLSARNRQKRFVLSGG--RWEKTDLTYRILRFPWQLVQEQVRQTMA 131

Query: 143 RAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDA 202
            A  +WS VTPLTFT V+   ADI+I F    HGD  PFDG  G+LAHAF P    +GD 
Sbjct: 132 EALKVWSDVTPLTFTEVHEGRADIMIDFARYWHGDDLPFDGPGGILAHAFFPKTHREGDV 191

Query: 203 HFDDDELWSLG 213
           HFD DE W++G
Sbjct: 192 HFDYDETWTIG 202


>gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens]
          Length = 2355

 Score =  142 bits (359), Expect = 8e-34
 Identities = 75/174 (43%), Positives = 100/174 (57%), Gaps = 23/174 (13%)

Query: 241 YSACTTDGR---SDGLPWCSTTANYD---TDDRFGFCPSERLYTQD--GNADGKPCQFPF 292
           Y  C TD     S G+ W  T  N     T    G    E   TQ   GN++G+PC  PF
Sbjct: 305 YGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPF 364

Query: 293 IFQGQSYSACTTDGRSDGYRWCATTANYDRDKLFGFCPTRADSTVM----GGNSAGELCV 348
            + G+++ +CTT+GR DG+ WC+TT+NY++D+ + FC    D TV+    GGNS G LC 
Sbjct: 365 TYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFC---TDHTVLVQTRGGNSNGALCH 421

Query: 349 FPFTFLGKEYSTCTSEGRGDGRLWCATTSNFDSDKKWGFCPDQGYSLFLVAAHE 402
           FPF +    Y+ CTSEGR D   WC TT N+D+D+K+GFCP        +AAHE
Sbjct: 422 FPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCP--------MAAHE 467



 Score =  136 bits (342), Expect = 8e-32
 Identities = 60/138 (43%), Positives = 84/138 (60%), Gaps = 8/138 (5%)

Query: 212 LGKGV------VVPTRFGNADGAACHFPFIFEGRSYSACTTDGRSDGLPWCSTTANYDTD 265
           LG GV      V  T  GN++G  C  PF + GR++ +CTT+GR DG  WCSTT+NY+ D
Sbjct: 336 LGNGVSCQETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQD 395

Query: 266 DRFGFCPSERLY--TQDGNADGKPCQFPFIFQGQSYSACTTDGRSDGYRWCATTANYDRD 323
            ++ FC    +   T+ GN++G  C FPF++   +Y+ CT++GR D  +WC TT NYD D
Sbjct: 396 QKYSFCTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDAD 455

Query: 324 KLFGFCPTRADSTVMGGN 341
           + FGFCP  A   +   N
Sbjct: 456 QKFGFCPMAAHEEICTTN 473



 Score = 86.3 bits (212), Expect = 9e-17
 Identities = 34/73 (46%), Positives = 51/73 (69%), Gaps = 2/73 (2%)

Query: 202 AHFDDDELWSL--GKGVVVPTRFGNADGAACHFPFIFEGRSYSACTTDGRSDGLPWCSTT 259
           ++++ D+ +S      V+V TR GN++GA CHFPF++   +Y+ CT++GR D + WC TT
Sbjct: 390 SNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTT 449

Query: 260 ANYDTDDRFGFCP 272
            NYD D +FGFCP
Sbjct: 450 QNYDADQKFGFCP 462



 Score = 83.6 bits (205), Expect = 6e-16
 Identities = 44/103 (42%), Positives = 56/103 (54%), Gaps = 7/103 (6%)

Query: 295 QGQSYSACTTDGR---SDGYRWCATTANYDR-DKLFG---FCPTRADSTVMGGNSAGELC 347
           Q   Y  C TD     S G +W  T  N        G    C   A +   GGNS GE C
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360

Query: 348 VFPFTFLGKEYSTCTSEGRGDGRLWCATTSNFDSDKKWGFCPD 390
           V PFT+ G+ + +CT+EGR DG LWC+TTSN++ D+K+ FC D
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTD 403


>gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens]
          Length = 2477

 Score =  142 bits (359), Expect = 8e-34
 Identities = 75/174 (43%), Positives = 100/174 (57%), Gaps = 23/174 (13%)

Query: 241 YSACTTDGR---SDGLPWCSTTANYD---TDDRFGFCPSERLYTQD--GNADGKPCQFPF 292
           Y  C TD     S G+ W  T  N     T    G    E   TQ   GN++G+PC  PF
Sbjct: 305 YGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPF 364

Query: 293 IFQGQSYSACTTDGRSDGYRWCATTANYDRDKLFGFCPTRADSTVM----GGNSAGELCV 348
            + G+++ +CTT+GR DG+ WC+TT+NY++D+ + FC    D TV+    GGNS G LC 
Sbjct: 365 TYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFC---TDHTVLVQTRGGNSNGALCH 421

Query: 349 FPFTFLGKEYSTCTSEGRGDGRLWCATTSNFDSDKKWGFCPDQGYSLFLVAAHE 402
           FPF +    Y+ CTSEGR D   WC TT N+D+D+K+GFCP        +AAHE
Sbjct: 422 FPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCP--------MAAHE 467



 Score =  136 bits (342), Expect = 8e-32
 Identities = 60/138 (43%), Positives = 84/138 (60%), Gaps = 8/138 (5%)

Query: 212 LGKGV------VVPTRFGNADGAACHFPFIFEGRSYSACTTDGRSDGLPWCSTTANYDTD 265
           LG GV      V  T  GN++G  C  PF + GR++ +CTT+GR DG  WCSTT+NY+ D
Sbjct: 336 LGNGVSCQETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQD 395

Query: 266 DRFGFCPSERLY--TQDGNADGKPCQFPFIFQGQSYSACTTDGRSDGYRWCATTANYDRD 323
            ++ FC    +   T+ GN++G  C FPF++   +Y+ CT++GR D  +WC TT NYD D
Sbjct: 396 QKYSFCTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDAD 455

Query: 324 KLFGFCPTRADSTVMGGN 341
           + FGFCP  A   +   N
Sbjct: 456 QKFGFCPMAAHEEICTTN 473



 Score = 86.3 bits (212), Expect = 9e-17
 Identities = 34/73 (46%), Positives = 51/73 (69%), Gaps = 2/73 (2%)

Query: 202 AHFDDDELWSL--GKGVVVPTRFGNADGAACHFPFIFEGRSYSACTTDGRSDGLPWCSTT 259
           ++++ D+ +S      V+V TR GN++GA CHFPF++   +Y+ CT++GR D + WC TT
Sbjct: 390 SNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTT 449

Query: 260 ANYDTDDRFGFCP 272
            NYD D +FGFCP
Sbjct: 450 QNYDADQKFGFCP 462



 Score = 83.6 bits (205), Expect = 6e-16
 Identities = 44/103 (42%), Positives = 56/103 (54%), Gaps = 7/103 (6%)

Query: 295 QGQSYSACTTDGR---SDGYRWCATTANYDR-DKLFG---FCPTRADSTVMGGNSAGELC 347
           Q   Y  C TD     S G +W  T  N        G    C   A +   GGNS GE C
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360

Query: 348 VFPFTFLGKEYSTCTSEGRGDGRLWCATTSNFDSDKKWGFCPD 390
           V PFT+ G+ + +CT+EGR DG LWC+TTSN++ D+K+ FC D
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTD 403


>gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens]
          Length = 2330

 Score =  142 bits (359), Expect = 8e-34
 Identities = 75/174 (43%), Positives = 100/174 (57%), Gaps = 23/174 (13%)

Query: 241 YSACTTDGR---SDGLPWCSTTANYD---TDDRFGFCPSERLYTQD--GNADGKPCQFPF 292
           Y  C TD     S G+ W  T  N     T    G    E   TQ   GN++G+PC  PF
Sbjct: 305 YGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPF 364

Query: 293 IFQGQSYSACTTDGRSDGYRWCATTANYDRDKLFGFCPTRADSTVM----GGNSAGELCV 348
            + G+++ +CTT+GR DG+ WC+TT+NY++D+ + FC    D TV+    GGNS G LC 
Sbjct: 365 TYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFC---TDHTVLVQTRGGNSNGALCH 421

Query: 349 FPFTFLGKEYSTCTSEGRGDGRLWCATTSNFDSDKKWGFCPDQGYSLFLVAAHE 402
           FPF +    Y+ CTSEGR D   WC TT N+D+D+K+GFCP        +AAHE
Sbjct: 422 FPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCP--------MAAHE 467



 Score =  136 bits (342), Expect = 8e-32
 Identities = 60/138 (43%), Positives = 84/138 (60%), Gaps = 8/138 (5%)

Query: 212 LGKGV------VVPTRFGNADGAACHFPFIFEGRSYSACTTDGRSDGLPWCSTTANYDTD 265
           LG GV      V  T  GN++G  C  PF + GR++ +CTT+GR DG  WCSTT+NY+ D
Sbjct: 336 LGNGVSCQETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQD 395

Query: 266 DRFGFCPSERLY--TQDGNADGKPCQFPFIFQGQSYSACTTDGRSDGYRWCATTANYDRD 323
            ++ FC    +   T+ GN++G  C FPF++   +Y+ CT++GR D  +WC TT NYD D
Sbjct: 396 QKYSFCTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDAD 455

Query: 324 KLFGFCPTRADSTVMGGN 341
           + FGFCP  A   +   N
Sbjct: 456 QKFGFCPMAAHEEICTTN 473



 Score = 86.3 bits (212), Expect = 9e-17
 Identities = 34/73 (46%), Positives = 51/73 (69%), Gaps = 2/73 (2%)

Query: 202 AHFDDDELWSL--GKGVVVPTRFGNADGAACHFPFIFEGRSYSACTTDGRSDGLPWCSTT 259
           ++++ D+ +S      V+V TR GN++GA CHFPF++   +Y+ CT++GR D + WC TT
Sbjct: 390 SNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTT 449

Query: 260 ANYDTDDRFGFCP 272
            NYD D +FGFCP
Sbjct: 450 QNYDADQKFGFCP 462



 Score = 83.6 bits (205), Expect = 6e-16
 Identities = 44/103 (42%), Positives = 56/103 (54%), Gaps = 7/103 (6%)

Query: 295 QGQSYSACTTDGR---SDGYRWCATTANYDR-DKLFG---FCPTRADSTVMGGNSAGELC 347
           Q   Y  C TD     S G +W  T  N        G    C   A +   GGNS GE C
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360

Query: 348 VFPFTFLGKEYSTCTSEGRGDGRLWCATTSNFDSDKKWGFCPD 390
           V PFT+ G+ + +CT+EGR DG LWC+TTSN++ D+K+ FC D
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTD 403


>gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens]
          Length = 2296

 Score =  142 bits (359), Expect = 8e-34
 Identities = 75/174 (43%), Positives = 100/174 (57%), Gaps = 23/174 (13%)

Query: 241 YSACTTDGR---SDGLPWCSTTANYD---TDDRFGFCPSERLYTQD--GNADGKPCQFPF 292
           Y  C TD     S G+ W  T  N     T    G    E   TQ   GN++G+PC  PF
Sbjct: 305 YGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPF 364

Query: 293 IFQGQSYSACTTDGRSDGYRWCATTANYDRDKLFGFCPTRADSTVM----GGNSAGELCV 348
            + G+++ +CTT+GR DG+ WC+TT+NY++D+ + FC    D TV+    GGNS G LC 
Sbjct: 365 TYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFC---TDHTVLVQTRGGNSNGALCH 421

Query: 349 FPFTFLGKEYSTCTSEGRGDGRLWCATTSNFDSDKKWGFCPDQGYSLFLVAAHE 402
           FPF +    Y+ CTSEGR D   WC TT N+D+D+K+GFCP        +AAHE
Sbjct: 422 FPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCP--------MAAHE 467



 Score =  136 bits (342), Expect = 8e-32
 Identities = 60/138 (43%), Positives = 84/138 (60%), Gaps = 8/138 (5%)

Query: 212 LGKGV------VVPTRFGNADGAACHFPFIFEGRSYSACTTDGRSDGLPWCSTTANYDTD 265
           LG GV      V  T  GN++G  C  PF + GR++ +CTT+GR DG  WCSTT+NY+ D
Sbjct: 336 LGNGVSCQETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQD 395

Query: 266 DRFGFCPSERLY--TQDGNADGKPCQFPFIFQGQSYSACTTDGRSDGYRWCATTANYDRD 323
            ++ FC    +   T+ GN++G  C FPF++   +Y+ CT++GR D  +WC TT NYD D
Sbjct: 396 QKYSFCTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDAD 455

Query: 324 KLFGFCPTRADSTVMGGN 341
           + FGFCP  A   +   N
Sbjct: 456 QKFGFCPMAAHEEICTTN 473



 Score = 86.3 bits (212), Expect = 9e-17
 Identities = 34/73 (46%), Positives = 51/73 (69%), Gaps = 2/73 (2%)

Query: 202 AHFDDDELWSL--GKGVVVPTRFGNADGAACHFPFIFEGRSYSACTTDGRSDGLPWCSTT 259
           ++++ D+ +S      V+V TR GN++GA CHFPF++   +Y+ CT++GR D + WC TT
Sbjct: 390 SNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTT 449

Query: 260 ANYDTDDRFGFCP 272
            NYD D +FGFCP
Sbjct: 450 QNYDADQKFGFCP 462



 Score = 83.6 bits (205), Expect = 6e-16
 Identities = 44/103 (42%), Positives = 56/103 (54%), Gaps = 7/103 (6%)

Query: 295 QGQSYSACTTDGR---SDGYRWCATTANYDR-DKLFG---FCPTRADSTVMGGNSAGELC 347
           Q   Y  C TD     S G +W  T  N        G    C   A +   GGNS GE C
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360

Query: 348 VFPFTFLGKEYSTCTSEGRGDGRLWCATTSNFDSDKKWGFCPD 390
           V PFT+ G+ + +CT+EGR DG LWC+TTSN++ D+K+ FC D
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTD 403


>gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens]
          Length = 2421

 Score =  142 bits (359), Expect = 8e-34
 Identities = 75/174 (43%), Positives = 100/174 (57%), Gaps = 23/174 (13%)

Query: 241 YSACTTDGR---SDGLPWCSTTANYD---TDDRFGFCPSERLYTQD--GNADGKPCQFPF 292
           Y  C TD     S G+ W  T  N     T    G    E   TQ   GN++G+PC  PF
Sbjct: 305 YGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPF 364

Query: 293 IFQGQSYSACTTDGRSDGYRWCATTANYDRDKLFGFCPTRADSTVM----GGNSAGELCV 348
            + G+++ +CTT+GR DG+ WC+TT+NY++D+ + FC    D TV+    GGNS G LC 
Sbjct: 365 TYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFC---TDHTVLVQTRGGNSNGALCH 421

Query: 349 FPFTFLGKEYSTCTSEGRGDGRLWCATTSNFDSDKKWGFCPDQGYSLFLVAAHE 402
           FPF +    Y+ CTSEGR D   WC TT N+D+D+K+GFCP        +AAHE
Sbjct: 422 FPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCP--------MAAHE 467



 Score =  136 bits (342), Expect = 8e-32
 Identities = 60/138 (43%), Positives = 84/138 (60%), Gaps = 8/138 (5%)

Query: 212 LGKGV------VVPTRFGNADGAACHFPFIFEGRSYSACTTDGRSDGLPWCSTTANYDTD 265
           LG GV      V  T  GN++G  C  PF + GR++ +CTT+GR DG  WCSTT+NY+ D
Sbjct: 336 LGNGVSCQETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQD 395

Query: 266 DRFGFCPSERLY--TQDGNADGKPCQFPFIFQGQSYSACTTDGRSDGYRWCATTANYDRD 323
            ++ FC    +   T+ GN++G  C FPF++   +Y+ CT++GR D  +WC TT NYD D
Sbjct: 396 QKYSFCTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDAD 455

Query: 324 KLFGFCPTRADSTVMGGN 341
           + FGFCP  A   +   N
Sbjct: 456 QKFGFCPMAAHEEICTTN 473



 Score = 86.3 bits (212), Expect = 9e-17
 Identities = 34/73 (46%), Positives = 51/73 (69%), Gaps = 2/73 (2%)

Query: 202 AHFDDDELWSL--GKGVVVPTRFGNADGAACHFPFIFEGRSYSACTTDGRSDGLPWCSTT 259
           ++++ D+ +S      V+V TR GN++GA CHFPF++   +Y+ CT++GR D + WC TT
Sbjct: 390 SNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTT 449

Query: 260 ANYDTDDRFGFCP 272
            NYD D +FGFCP
Sbjct: 450 QNYDADQKFGFCP 462



 Score = 83.6 bits (205), Expect = 6e-16
 Identities = 44/103 (42%), Positives = 56/103 (54%), Gaps = 7/103 (6%)

Query: 295 QGQSYSACTTDGR---SDGYRWCATTANYDR-DKLFG---FCPTRADSTVMGGNSAGELC 347
           Q   Y  C TD     S G +W  T  N        G    C   A +   GGNS GE C
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360

Query: 348 VFPFTFLGKEYSTCTSEGRGDGRLWCATTSNFDSDKKWGFCPD 390
           V PFT+ G+ + +CT+EGR DG LWC+TTSN++ D+K+ FC D
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTD 403


>gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens]
          Length = 2176

 Score =  142 bits (359), Expect = 8e-34
 Identities = 75/174 (43%), Positives = 100/174 (57%), Gaps = 23/174 (13%)

Query: 241 YSACTTDGR---SDGLPWCSTTANYD---TDDRFGFCPSERLYTQD--GNADGKPCQFPF 292
           Y  C TD     S G+ W  T  N     T    G    E   TQ   GN++G+PC  PF
Sbjct: 305 YGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPF 364

Query: 293 IFQGQSYSACTTDGRSDGYRWCATTANYDRDKLFGFCPTRADSTVM----GGNSAGELCV 348
            + G+++ +CTT+GR DG+ WC+TT+NY++D+ + FC    D TV+    GGNS G LC 
Sbjct: 365 TYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFC---TDHTVLVQTRGGNSNGALCH 421

Query: 349 FPFTFLGKEYSTCTSEGRGDGRLWCATTSNFDSDKKWGFCPDQGYSLFLVAAHE 402
           FPF +    Y+ CTSEGR D   WC TT N+D+D+K+GFCP        +AAHE
Sbjct: 422 FPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCP--------MAAHE 467



 Score =  136 bits (342), Expect = 8e-32
 Identities = 60/138 (43%), Positives = 84/138 (60%), Gaps = 8/138 (5%)

Query: 212 LGKGV------VVPTRFGNADGAACHFPFIFEGRSYSACTTDGRSDGLPWCSTTANYDTD 265
           LG GV      V  T  GN++G  C  PF + GR++ +CTT+GR DG  WCSTT+NY+ D
Sbjct: 336 LGNGVSCQETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQD 395

Query: 266 DRFGFCPSERLY--TQDGNADGKPCQFPFIFQGQSYSACTTDGRSDGYRWCATTANYDRD 323
            ++ FC    +   T+ GN++G  C FPF++   +Y+ CT++GR D  +WC TT NYD D
Sbjct: 396 QKYSFCTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDAD 455

Query: 324 KLFGFCPTRADSTVMGGN 341
           + FGFCP  A   +   N
Sbjct: 456 QKFGFCPMAAHEEICTTN 473



 Score = 86.3 bits (212), Expect = 9e-17
 Identities = 34/73 (46%), Positives = 51/73 (69%), Gaps = 2/73 (2%)

Query: 202 AHFDDDELWSL--GKGVVVPTRFGNADGAACHFPFIFEGRSYSACTTDGRSDGLPWCSTT 259
           ++++ D+ +S      V+V TR GN++GA CHFPF++   +Y+ CT++GR D + WC TT
Sbjct: 390 SNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTT 449

Query: 260 ANYDTDDRFGFCP 272
            NYD D +FGFCP
Sbjct: 450 QNYDADQKFGFCP 462



 Score = 83.6 bits (205), Expect = 6e-16
 Identities = 44/103 (42%), Positives = 56/103 (54%), Gaps = 7/103 (6%)

Query: 295 QGQSYSACTTDGR---SDGYRWCATTANYDR-DKLFG---FCPTRADSTVMGGNSAGELC 347
           Q   Y  C TD     S G +W  T  N        G    C   A +   GGNS GE C
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360

Query: 348 VFPFTFLGKEYSTCTSEGRGDGRLWCATTSNFDSDKKWGFCPD 390
           V PFT+ G+ + +CT+EGR DG LWC+TTSN++ D+K+ FC D
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTD 403


>gi|47132547 fibronectin 1 isoform 7 preproprotein [Homo sapiens]
          Length = 657

 Score =  142 bits (359), Expect = 8e-34
 Identities = 75/174 (43%), Positives = 100/174 (57%), Gaps = 23/174 (13%)

Query: 241 YSACTTDGR---SDGLPWCSTTANYD---TDDRFGFCPSERLYTQD--GNADGKPCQFPF 292
           Y  C TD     S G+ W  T  N     T    G    E   TQ   GN++G+PC  PF
Sbjct: 305 YGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPF 364

Query: 293 IFQGQSYSACTTDGRSDGYRWCATTANYDRDKLFGFCPTRADSTVM----GGNSAGELCV 348
            + G+++ +CTT+GR DG+ WC+TT+NY++D+ + FC    D TV+    GGNS G LC 
Sbjct: 365 TYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFC---TDHTVLVQTRGGNSNGALCH 421

Query: 349 FPFTFLGKEYSTCTSEGRGDGRLWCATTSNFDSDKKWGFCPDQGYSLFLVAAHE 402
           FPF +    Y+ CTSEGR D   WC TT N+D+D+K+GFCP        +AAHE
Sbjct: 422 FPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCP--------MAAHE 467



 Score =  136 bits (342), Expect = 8e-32
 Identities = 60/138 (43%), Positives = 84/138 (60%), Gaps = 8/138 (5%)

Query: 212 LGKGV------VVPTRFGNADGAACHFPFIFEGRSYSACTTDGRSDGLPWCSTTANYDTD 265
           LG GV      V  T  GN++G  C  PF + GR++ +CTT+GR DG  WCSTT+NY+ D
Sbjct: 336 LGNGVSCQETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQD 395

Query: 266 DRFGFCPSERLY--TQDGNADGKPCQFPFIFQGQSYSACTTDGRSDGYRWCATTANYDRD 323
            ++ FC    +   T+ GN++G  C FPF++   +Y+ CT++GR D  +WC TT NYD D
Sbjct: 396 QKYSFCTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDAD 455

Query: 324 KLFGFCPTRADSTVMGGN 341
           + FGFCP  A   +   N
Sbjct: 456 QKFGFCPMAAHEEICTTN 473



 Score = 86.3 bits (212), Expect = 9e-17
 Identities = 34/73 (46%), Positives = 51/73 (69%), Gaps = 2/73 (2%)

Query: 202 AHFDDDELWSL--GKGVVVPTRFGNADGAACHFPFIFEGRSYSACTTDGRSDGLPWCSTT 259
           ++++ D+ +S      V+V TR GN++GA CHFPF++   +Y+ CT++GR D + WC TT
Sbjct: 390 SNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTT 449

Query: 260 ANYDTDDRFGFCP 272
            NYD D +FGFCP
Sbjct: 450 QNYDADQKFGFCP 462



 Score = 83.6 bits (205), Expect = 6e-16
 Identities = 44/103 (42%), Positives = 56/103 (54%), Gaps = 7/103 (6%)

Query: 295 QGQSYSACTTDGR---SDGYRWCATTANYDR-DKLFG---FCPTRADSTVMGGNSAGELC 347
           Q   Y  C TD     S G +W  T  N        G    C   A +   GGNS GE C
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360

Query: 348 VFPFTFLGKEYSTCTSEGRGDGRLWCATTSNFDSDKKWGFCPD 390
           V PFT+ G+ + +CT+EGR DG LWC+TTSN++ D+K+ FC D
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTD 403


>gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens]
          Length = 467

 Score =  142 bits (358), Expect = 1e-33
 Identities = 68/138 (49%), Positives = 87/138 (63%)

Query: 74  LQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFQTFEGDLKWHHHNITYWIQNYSEDLP 133
           +Q+   L  TG+ +  TL  M+ PRCGVPD G F    G+ KW   N+TY I+NY+  L 
Sbjct: 66  MQRFFGLNVTGKPNEETLDMMKKPRCGVPDSGGFMLTPGNPKWERTNLTYRIRNYTPQLS 125

Query: 134 RAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFP 193
            A ++ A   AF LWS  +PL FTR+   +ADI I F   +HGD  PFDG +G+LAHAF 
Sbjct: 126 EAEVERAIKDAFELWSVASPLIFTRISQGEADINIAFYQRDHGDNSPFDGPNGILAHAFQ 185

Query: 194 PGPGIQGDAHFDDDELWS 211
           PG GI GDAHFD +E W+
Sbjct: 186 PGQGIGGDAHFDAEETWT 203



 Score =  120 bits (301), Expect = 4e-27
 Identities = 91/308 (29%), Positives = 134/308 (43%), Gaps = 63/308 (20%)

Query: 377 SNFDSDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRF--TEGPPLHKD 434
           ++FD+++ W       Y+LFLVAAHEFGH+LGL HSS P ALMYP Y F  T    L +D
Sbjct: 194 AHFDAEETWTNT-SANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNYAFRETSNYSLPQD 252

Query: 435 DVNGIRHLYGPRPEPEPRPPTTTTPQPTAPPTVCPTGPPTVHPSERPTAGPTGPPSAGPT 494
           D++GI+ +YG    P                 + PTGP T  P +               
Sbjct: 253 DIDGIQAIYGLSSNP-----------------IQPTGPSTPKPCD--------------- 280

Query: 495 GPPTAGPSTATTVPLSPVDDACNVNIFDAIAEIGNQLYLFKDGKYWRFSEGRGSRPQGPF 554
                 PS                  FDAI  +  ++  FKD  +WR    +  R +  F
Sbjct: 281 ------PSLT----------------FDAITTLRGEILFFKDRYFWR-RHPQLQRVEMNF 317

Query: 555 LIADKWPALPRKLDSVFEERLSKKLFFFSGRQVWVYTGASVLG--PRRLDKLGLGADVAQ 612
            I+  WP+LP  + + +E+     +F F G Q W  +G  +L   P+ +   G  + V  
Sbjct: 318 -ISLFWPSLPTGIQAAYEDFDRDLIFLFKGNQYWALSGYDILQGYPKDISNYGFPSSVQA 376

Query: 613 VTGALRSGRGKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVPLDTHDVFQYREKAY 672
           +  A+   R K   F   + WR+D + Q ++P     +   FPG+      VFQ     +
Sbjct: 377 IDAAV-FYRSKTYFFVNDQFWRYDNQRQFMEPGYPKSISGAFPGIESKVDAVFQQEHFFH 435

Query: 673 -FCQDRFY 679
            F   R+Y
Sbjct: 436 VFSGPRYY 443


>gi|5729929 matrix metalloproteinase 24 preproprotein [Homo sapiens]
          Length = 645

 Score =  142 bits (357), Expect = 1e-33
 Identities = 109/321 (33%), Positives = 152/321 (47%), Gaps = 38/321 (11%)

Query: 377 SNFDSDKKW--GFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRF--TEGPPLH 432
           ++FDSD+ W  G     G  LFLVA HE GHALGL+HSS P A+M P Y++  T    L 
Sbjct: 256 THFDSDEPWTLGNANHDGNDLFLVAVHELGHALGLEHSSDPSAIMAPFYQYMETHNFKLP 315

Query: 433 KDDVNGIRHLYGPRPEP-EPRPPTTTTPQPTAPPTVCPTGPPTVH-PSERPTAGPTGPPS 490
           +DD+ GI+ +YGP  EP EP     T P PT P          +H PSER       PP 
Sbjct: 316 QDDLQGIQKIYGPPAEPLEP-----TRPLPTLPVR-------RIHSPSERKHERQPRPPR 363

Query: 491 AGPTGPPTAG-PSTATTVPLSPVDDACNVNIFDAIAEIGNQLYLFKDGKYWRFSEGRGSR 549
                PP    PST  T P     + C+ N F+ +A    ++++FKD  +WR    R   
Sbjct: 364 -----PPLGDRPSTPGTKP-----NICDGN-FNTVALFRGEMFVFKDRWFWRLRNNRVQE 412

Query: 550 PQGPFLIADKWPALPRKLDSVFEERLSKKLFFFSGRQVWVYTGASVLG--PRRLDKLGLG 607
              P  I   W  LP ++D+ + ER   +  FF G + WV+   +V    P  L +LG  
Sbjct: 413 GY-PMQIEQFWKGLPARIDAAY-ERADGRFVFFKGDKYWVFKEVTVEPGYPHSLGELGSC 470

Query: 608 ADVAQVTGALR-SGRGKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVPLDTHDVFQ 666
                +  ALR    GK   F G R WR+  + +  DP     +  ++ G+P      F 
Sbjct: 471 LPREGIDTALRWEPVGKTYFFKGERYWRYSEERRATDPGYPKPI-TVWKGIPQAPQGAFI 529

Query: 667 YRE--KAYFCQDRFYWRVSSR 685
            +E    YF + R YW+  ++
Sbjct: 530 SKEGYYTYFYKGRDYWKFDNQ 550



 Score =  129 bits (325), Expect = 7e-30
 Identities = 82/233 (35%), Positives = 109/233 (46%), Gaps = 26/233 (11%)

Query: 7   LVLVLLVLGCCF------------AAPRQRQSTLVLFPGDLRTNLTDRQLAEEYLYRYGY 54
           L+L+LL   CC             A  R   +  V    +       +   + Y Y   Y
Sbjct: 35  LLLLLLPALCCLPGAARAAAAAAGAGNRAAVAVAVARADEAEAPFAGQNWLKSYGYLLPY 94

Query: 55  TRVAEMRGESKSLGPALLLLQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFQTFEGDL 114
              A     +K+L  A+  +Q+   +P TG LD  T++ M+ PRCGVPD         + 
Sbjct: 95  DSRASALHSAKALQSAVSTMQQFYGIPVTGVLDQTTIEWMKKPRCGVPDHPHLSRRRRNK 154

Query: 115 -------KWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVY------- 160
                  KW   +ITY I NY+  +       A  +AF +W  VTPLTF  V        
Sbjct: 155 RYALTGQKWRQKHITYSIHNYTPKVGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEIKSD 214

Query: 161 SRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLG 213
            ++ADI+I F    HGD  PFDG+ G LAHA+ PGPGI GD HFD DE W+LG
Sbjct: 215 RKEADIMIFFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLG 267


>gi|4505219 matrix metalloproteinase 7 preproprotein [Homo sapiens]
          Length = 267

 Score =  141 bits (356), Expect = 2e-33
 Identities = 73/172 (42%), Positives = 99/172 (57%), Gaps = 2/172 (1%)

Query: 45  AEEYLYRYGYTRVAEMRGESKSLGPALLLLQKQLSLPETGELDSATLKAMRTPRCGVPDL 104
           A++YL R+ Y   +E +  + SL   L  +QK   LP TG L+S  ++ M+ PRCGVPD+
Sbjct: 35  AQDYLKRF-YLYDSETKN-ANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPDV 92

Query: 105 GRFQTFEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDA 164
             +  F    KW    +TY I +Y+ DLP   +D   ++A  +W    PL F +V    A
Sbjct: 93  AEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTA 152

Query: 165 DIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGV 216
           DI+I F    HGD YPFDG    LAHAF PG G+ GDAHFD+DE W+ G  +
Sbjct: 153 DIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSL 204



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 38/102 (37%), Positives = 52/102 (50%), Gaps = 11/102 (10%)

Query: 349 FPFTFLGKEYSTCTSEGRGDGRLWCATTSNFDSDKKWGFCPDQGYSLFLVAAHEFGHALG 408
           +PF   G   +   + G G G       ++FD D++W      G +    A HE GH+LG
Sbjct: 167 YPFDGPGNTLAHAFAPGTGLGG-----DAHFDEDERWTDGSSLGINFLYAATHELGHSLG 221

Query: 409 LDHSSVPEALMYPMYRFTEGPP----LHKDDVNGIRHLYGPR 446
           + HSS P A+MYP Y    G P    L +DD+ GI+ LYG R
Sbjct: 222 MGHSSDPNAVMYPTY--GNGDPQNFKLSQDDIKGIQKLYGKR 261


>gi|4505211 matrix metalloproteinase 15 preproprotein [Homo sapiens]
          Length = 669

 Score =  141 bits (356), Expect = 2e-33
 Identities = 106/343 (30%), Positives = 155/343 (45%), Gaps = 27/343 (7%)

Query: 377 SNFDSDKKWGFCPDQ--GYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRF--TEGPPLH 432
           ++FD+D+ W F      G +LFLVA HE GHALGL+HSS P A+M P Y++   +   L 
Sbjct: 233 THFDADEPWTFSSTDLHGNNLFLVAVHELGHALGLEHSSNPNAIMAPFYQWKDVDNFKLP 292

Query: 433 KDDVNGIRHLYGPRPEPEPRPPTTTTPQPTAP-PTVCPTGPPTVHPSERPTAGPTGPPSA 491
           +DD+ GI+ LYG  P+ +        PQPT P PTV P  P    P  RP   P  PP  
Sbjct: 293 EDDLRGIQQLYG-TPDGQ--------PQPTQPLPTVTPRRPG--RPDHRPPRPPQPPPPG 341

Query: 492 G-PTGPPTAGPSTATTVPLSPVDDACNV--NIFDAIAEIGNQLYLFKDGKYWRFSEGRGS 548
           G P  PP  GP         P     N+    FD +A +  ++++FK   +WR    R  
Sbjct: 342 GKPERPPKPGPPVQPRATERPDQYGPNICDGDFDTVAMLRGEMFVFKGRWFWRVRHNR-V 400

Query: 549 RPQGPFLIADKWPALPRKLDSVFEERLSKKLFFFSGRQVWVYTGASVLG--PRRLDKLGL 606
               P  I   W  LP  + + + ER   +  FF G + W++  A++    P+ L   GL
Sbjct: 401 LDNYPMPIGHFWRGLPGDISAAY-ERQDGRFVFFKGDRYWLFREANLEPGYPQPLTSYGL 459

Query: 607 GADVAQVTGAL-RSGRGKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVPLDTHDVF 665
           G    ++  A+     G    F   R WRF+ + Q  DP     +  ++ G+P      F
Sbjct: 460 GIPYDRIDTAIWWEPTGHTFFFQEDRYWRFNEETQRGDPGYPKPIS-VWQGIPASPKGAF 518

Query: 666 QYREKA--YFCQDRFYWRVSSRSELNQVDQVGYVTYDILQCPE 706
              + A  YF +   YW+  +     +      +  D + C E
Sbjct: 519 LSNDAAYTYFYKGTKYWKFDNERLRMEPGYPKSILRDFMGCQE 561



 Score =  125 bits (313), Expect = 2e-28
 Identities = 74/190 (38%), Positives = 99/190 (52%), Gaps = 23/190 (12%)

Query: 45  AEEYLYRYGY----TRVAEMRGESKSLGPALLLLQKQLSLPETGELDSATLKAMRTPRCG 100
           AE +L  YGY    +R       ++ L  AL  +Q+   +P TG LD  T + M+ PRCG
Sbjct: 53  AENWLRLYGYLPQPSRHMSTMRSAQILASALAEMQRFYGIPVTGVLDEETKEWMKRPRCG 112

Query: 101 VPDL-----------GRFQTFEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWS 149
           VPD             R +      KW++H++T+ IQNY+E L      +A  RAF +W 
Sbjct: 113 VPDQFGVRVKANLRRRRKRYALTGRKWNNHHLTFSIQNYTEKLGWYHSMEAVRRAFRVWE 172

Query: 150 AVTPLTFTRV--------YSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGD 201
             TPL F  V          ++ADI++ F    HGD  PFDG  G LAHA+ PGPG+ GD
Sbjct: 173 QATPLVFQEVPYEDIRLRRQKEADIMVLFASGFHGDSSPFDGTGGFLAHAYFPGPGLGGD 232

Query: 202 AHFDDDELWS 211
            HFD DE W+
Sbjct: 233 THFDADEPWT 242


>gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein
           [Homo sapiens]
          Length = 607

 Score =  140 bits (353), Expect = 4e-33
 Identities = 102/319 (31%), Positives = 152/319 (47%), Gaps = 35/319 (10%)

Query: 377 SNFDSDKKW--GFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRF--TEGPPLH 432
           ++FDSD+ W  G     G  LFLVA HE GHALGL+HS+ P A+M P Y++  T+   L 
Sbjct: 220 THFDSDEPWTLGNPNHDGNDLFLVAVHELGHALGLEHSNDPTAIMAPFYQYMETDNFKLP 279

Query: 433 KDDVNGIRHLYGPRPEPEPRPPTTTTPQPTAPP-TVCPTGPPTVHPSERPTAGPTGPPSA 491
            DD+ GI+ +YGP   P+  PP  T P PT PP    P   P  +   +P   PTG PS 
Sbjct: 280 NDDLQGIQKIYGP---PDKIPP-PTRPLPTVPPHRSIPPADPRKNDRPKPPRPPTGRPSY 335

Query: 492 GPTGPPTAGPSTATTVPLSPVDDACNVNIFDAIAEIGNQLYLFKDGKYWRFSEGRGSRPQ 551
                P A P            + C+ N F+ +A +  ++++FKD  +WR    R     
Sbjct: 336 -----PGAKP------------NICDGN-FNTLAILRREMFVFKDQWFWRVRNNR-VMDG 376

Query: 552 GPFLIADKWPALPRKLDSVFEERLSKKLFFFSGRQVWVYTGASVLG--PRRLDKLGLGAD 609
            P  I   W  LP  +D+V+E        FF G + WV+   ++    P  L  LG G  
Sbjct: 377 YPMQITYFWRGLPPSIDAVYENS-DGNFVFFKGNKYWVFKDTTLQPGYPHDLITLGSGIP 435

Query: 610 VAQVTGAL-RSGRGKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVPLDTHDVFQYR 668
              +  A+     GK   F G R WR+  + + +DP     +  ++ G+P      F ++
Sbjct: 436 PHGIDSAIWWEDVGKTYFFKGDRYWRYSEEMKTMDPGYPKPI-TVWKGIPESPQGAFVHK 494

Query: 669 EK--AYFCQDRFYWRVSSR 685
           E    YF + + YW+ +++
Sbjct: 495 ENGFTYFYKGKEYWKFNNQ 513



 Score =  129 bits (323), Expect = 1e-29
 Identities = 81/200 (40%), Positives = 104/200 (52%), Gaps = 26/200 (13%)

Query: 46  EEYLYRYGYTRVAEMR----GESKSLGPALLLLQKQLSLPETGELDSATLKAMRTPRCGV 101
           E +L +YGY    + R      ++++  AL  +Q+   +  TG++D  T+  M+ PRCGV
Sbjct: 44  EVWLQKYGYLPPTDPRMSVLRSAETMQSALAAMQQFYGINMTGKVDRNTIDWMKKPRCGV 103

Query: 102 PDLGRFQT----------FEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAV 151
           PD  R  +            G  KW H +ITY I+N +  +       A  RAF +W  V
Sbjct: 104 PDQTRGSSKFHIRRKRYALTGQ-KWQHKHITYSIKNVTPKVGDPETRKAIRRAFDVWQNV 162

Query: 152 TPLTFTRV-YS------RDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHF 204
           TPLTF  V YS      RD DI I F    HGD  PFDG+ G LAHA+ PGPGI GD HF
Sbjct: 163 TPLTFEEVPYSELENGKRDVDITIIFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHF 222

Query: 205 DDDELWSLGKGVVVPTRFGN 224
           D DE W+LG     P   GN
Sbjct: 223 DSDEPWTLGN----PNHDGN 238


>gi|73808268 matrix metalloproteinase 27 [Homo sapiens]
          Length = 513

 Score =  140 bits (352), Expect = 5e-33
 Identities = 86/202 (42%), Positives = 120/202 (59%), Gaps = 16/202 (7%)

Query: 38  NLTDRQLAEEYLYRYGYTRVAE----MRGESKSL-GPALLLLQKQLSLPETGELDSATLK 92
           N  + QLA+ YL ++ Y+   E    ++ +++SL    +  +Q    L  TG+LDS TL+
Sbjct: 26  NEENMQLAQAYLNQF-YSLEIEGNHLVQSKNRSLIDDKIREMQAFFGLTVTGKLDSNTLE 84

Query: 93  AMRTPRCGVPDLGRF-QTFEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAV 151
            M+TPRCGVPD+G++  T  G   W  +N+TY I NY+ D+ RA +D+A      +WS V
Sbjct: 85  IMKTPRCGVPDVGQYGYTLPG---WRKYNLTYRIINYTPDMARAAVDEAIQEGLEVWSKV 141

Query: 152 TPLTFTRVYSRDADIVIQFGVAEHGD-GYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELW 210
           TPL FT++    ADI+I F    HG     FDG  G+L HAFPPGPG+ GD HFD+DE W
Sbjct: 142 TPLKFTKISKGIADIMIAFRTRVHGRCPRYFDGPLGVLGHAFPPGPGLGGDTHFDEDENW 201

Query: 211 SL-GKG----VVVPTRFGNADG 227
           +  G G    +V    FG+A G
Sbjct: 202 TKDGAGFNLFLVAAHEFGHALG 223



 Score =  108 bits (270), Expect = 2e-23
 Identities = 89/304 (29%), Positives = 128/304 (42%), Gaps = 66/304 (21%)

Query: 377 SNFDSDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTEGP--PLHKD 434
           ++FD D+ W      G++LFLVAAHEFGHALGL HS+   ALM+P Y   +    PL +D
Sbjct: 193 THFDEDENWTK-DGAGFNLFLVAAHEFGHALGLSHSNDQTALMFPNYVSLDPRKYPLSQD 251

Query: 435 DVNGIRHLYGPRPEPEPRPPTTTTPQPTAPPTVCPTGPPTVHPSERPTAGPTGPPSAGPT 494
           D+NGI+ +YG  P+   +P      +PT P                              
Sbjct: 252 DINGIQSIYGGLPKEPAKPK-----EPTIP------------------------------ 276

Query: 495 GPPTAGPSTATTVPLSPVDDACNVNI-FDAIAEIGNQLYLFKDGKYWRFSEGRGSRPQGP 553
                               AC+ ++ FDAI     ++  FK    WR            
Sbjct: 277 -------------------HACDPDLTFDAITTFRREVMFFKGRHLWRIYYDITDVEFE- 316

Query: 554 FLIADKWPALPRKLDSVFEERLSKKLFFFSGRQVWVYTGASVLG--PRRLDKLGLGADVA 611
            LIA  WP+LP  L + +E    K +  F     W+  G +VL   P+ +  LG    V 
Sbjct: 317 -LIASFWPSLPADLQAAYENPRDK-ILVFKDENFWMIRGYAVLPDYPKSIHTLGFPGRVK 374

Query: 612 QVTGAL--RSGRGKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVPLDTHDVFQYRE 669
           ++  A+  ++ R K   F G   WRFD   Q +D      V + FPG+ +     FQY+ 
Sbjct: 375 KIDAAVCDKTTR-KTYFFVGIWCWRFDEMTQTMDKGFPQRVVKHFPGISIRVDAAFQYKG 433

Query: 670 KAYF 673
             +F
Sbjct: 434 FFFF 437


>gi|4826834 matrix metalloproteinase 14 preproprotein [Homo sapiens]
          Length = 582

 Score =  135 bits (341), Expect = 1e-31
 Identities = 84/227 (37%), Positives = 115/227 (50%), Gaps = 35/227 (15%)

Query: 7   LVLVLLVLGCCFAAPRQRQSTLVLFPGDLRTNLTDRQLAEEYLYRYGYTRVAEMRGESK- 65
           L+L LL LG   A+    QS+                  E +L +YGY    ++R  ++ 
Sbjct: 11  LLLPLLTLGTALASLGSAQSSSFS--------------PEAWLQQYGYLPPGDLRTHTQR 56

Query: 66  ---SLGPALLLLQKQLSLPETGELDSATLKAMRTPRCGVPD---------LGRFQTFEGD 113
              SL  A+  +QK   L  TG+ D+ T+KAMR PRCGVPD         + R +     
Sbjct: 57  SPQSLSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQG 116

Query: 114 LKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRV--------YSRDAD 165
           LKW H+ IT+ IQNY+  +      +A  +AF +W + TPL F  V        + + AD
Sbjct: 117 LKWQHNEITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEKQAD 176

Query: 166 IVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSL 212
           I+I F    HGD  PFDG+ G LAHA+ PGP I GD HFD  E W++
Sbjct: 177 IMIFFAEGFHGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTV 223



 Score =  116 bits (291), Expect = 6e-26
 Identities = 95/318 (29%), Positives = 147/318 (46%), Gaps = 50/318 (15%)

Query: 377 SNFDSDKKWGFCPDQ--GYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRF--TEGPPLH 432
           ++FDS + W    +   G  +FLVA HE GHALGL+HSS P A+M P Y++  TE   L 
Sbjct: 213 THFDSAEPWTVRNEDLNGNDIFLVAVHELGHALGLEHSSDPSAIMAPFYQWMDTENFVLP 272

Query: 433 KDDVNGIRHLYGPRPEPEPRPPTTTTPQPTAPPTVCPTGPPTVHPSERPTAGPTGPPSAG 492
            DD  GI+ LYG     E   PT   PQP        T  P+V         P  P +  
Sbjct: 273 DDDRRGIQQLYGG----ESGFPTKMPPQPRT------TSRPSV---------PDKPKN-- 311

Query: 493 PTGPPTAGPSTATTVPLSPVDDACNVNIFDAIAEIGNQLYLFKDGKYWRFSEGRGSRPQG 552
               PT GP+             C+ N FD +A +  ++++FK+  +WR    +      
Sbjct: 312 ----PTYGPNI------------CDGN-FDTVAMLRGEMFVFKERWFWRVRNNQ-VMDGY 353

Query: 553 PFLIADKWPALPRKLDSVFEERLSKKLFFFSGRQVWVYTGASVLG--PRRLDKLGLGADV 610
           P  I   W  LP  +++ + ER   K  FF G + WV+  AS+    P+ + +LG G   
Sbjct: 354 PMPIGQFWRGLPASINTAY-ERKDGKFVFFKGDKHWVFDEASLEPGYPKHIKELGRGLPT 412

Query: 611 AQVTGAL-RSGRGKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVPLDTHDVFQYRE 669
            ++  AL     GK   F G + +RF+ + + VD      + +++ G+P      F   +
Sbjct: 413 DKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNI-KVWEGIPESPRGSFMGSD 471

Query: 670 K--AYFCQDRFYWRVSSR 685
           +   YF +   YW+ +++
Sbjct: 472 EVFTYFYKGNKYWKFNNQ 489


>gi|11968059 matrix metalloproteinase 25 preproprotein [Homo
           sapiens]
          Length = 562

 Score =  134 bits (337), Expect = 3e-31
 Identities = 104/342 (30%), Positives = 145/342 (42%), Gaps = 52/342 (15%)

Query: 377 SNFDSDKKWGFCPD--QGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTEGPP---- 430
           ++FD ++ W F     +G  LF VA HEFGHALGL HSS P ++M P Y+   G P    
Sbjct: 207 THFDDEETWTFGSKDGEGTDLFAVAVHEFGHALGLGHSSAPNSIMRPFYQGPVGDPDKYR 266

Query: 431 LHKDDVNGIRHLYGPRPEPEPRPPTTTTPQPTAPPTVCPTGPPTVHPSERPTAGPTGPPS 490
           L +DD +G++ LYG  P+                            P ++PT  P  PP 
Sbjct: 267 LSQDDRDGLQQLYGKAPQT---------------------------PYDKPTRKPLAPPP 299

Query: 491 AGPTGPPTAGPSTATTVPLSPVDDACNVNIFDAIAEIGNQLYLFKDGKYWRFSEGRGSRP 550
             P  P        T  P  P+ D C  N FDAIA I  + + FK   +WR         
Sbjct: 300 QPPASP--------THSPSFPIPDRCEGN-FDAIANIRGETFFFKGPWFWRLQPSGQLVS 350

Query: 551 QGPFLIADKWPALP---RKLDSVFEERLSKKLFFFSGRQVWVYTGASVL-GPRRLDKLGL 606
             P  +   W  LP   R + + +      ++  FSG Q WV+    +  G R L +LGL
Sbjct: 351 PRPARLHRFWEGLPAQVRVVQAAYARHRDGRILLFSGPQFWVFQDRQLEGGARPLTELGL 410

Query: 607 --GADVAQVTGALRSGRGKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVPLDTHDV 664
             G +V  V    ++  GK  L  GR+ WR+D  A   DP    ++  ++ G P    DV
Sbjct: 411 PPGEEVDAVFSWPQN--GKTYLVRGRQYWRYDEAAARPDPGYPRDLS-LWEGAPPSPDDV 467

Query: 665 -FQYREKAYFCQDRFYWRVSSRSELNQVDQVGYVTYDILQCP 705
                   YF +   YWR    S   + D    +  + L CP
Sbjct: 468 TVSNAGDTYFFKGAHYWRFPKNSIKTEPDAPQPMGPNWLDCP 509



 Score =  106 bits (265), Expect = 6e-23
 Identities = 69/193 (35%), Positives = 98/193 (50%), Gaps = 22/193 (11%)

Query: 41  DRQLAEEYLYRYGYT-----RVAEMRGESKSLGPALLLLQKQLSLPETGELDSATLKAMR 95
           D  L  ++L RYGY        A+++   K L  A+ ++Q+   LPETG +D  T+  MR
Sbjct: 28  DVSLGVDWLTRYGYLPPPHPAQAQLQSPEK-LRDAIKVMQRFAGLPETGRMDPGTVATMR 86

Query: 96  TPRCGVPDL---------GRFQTFEGDLKWHHHNITYWIQNY--SEDLPRAVIDDAFARA 144
            PRC +PD+          R     G + W    +T+ ++++  S  L +  +    + A
Sbjct: 87  KPRCSLPDVLGVAGLVRRRRRYALSGSV-WKKRTLTWRVRSFPQSSQLSQETVRVLMSYA 145

Query: 145 FALWSAVTPLTFTRVYS---RDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGP-GIQG 200
              W   + LTF  V S   ++ DI+I F  A H D YPFDG  G LAHAF PG   I G
Sbjct: 146 LMAWGMESGLTFHEVDSPQGQEPDILIDFARAFHQDSYPFDGLGGTLAHAFFPGEHPISG 205

Query: 201 DAHFDDDELWSLG 213
           D HFDD+E W+ G
Sbjct: 206 DTHFDDEETWTFG 218


>gi|149999365 matrix metalloproteinase 16 isoform 2 preproprotein
           [Homo sapiens]
          Length = 457

 Score =  129 bits (323), Expect = 1e-29
 Identities = 81/200 (40%), Positives = 104/200 (52%), Gaps = 26/200 (13%)

Query: 46  EEYLYRYGYTRVAEMR----GESKSLGPALLLLQKQLSLPETGELDSATLKAMRTPRCGV 101
           E +L +YGY    + R      ++++  AL  +Q+   +  TG++D  T+  M+ PRCGV
Sbjct: 44  EVWLQKYGYLPPTDPRMSVLRSAETMQSALAAMQQFYGINMTGKVDRNTIDWMKKPRCGV 103

Query: 102 PDLGRFQT----------FEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAV 151
           PD  R  +            G  KW H +ITY I+N +  +       A  RAF +W  V
Sbjct: 104 PDQTRGSSKFHIRRKRYALTGQ-KWQHKHITYSIKNVTPKVGDPETRKAIRRAFDVWQNV 162

Query: 152 TPLTFTRV-YS------RDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHF 204
           TPLTF  V YS      RD DI I F    HGD  PFDG+ G LAHA+ PGPGI GD HF
Sbjct: 163 TPLTFEEVPYSELENGKRDVDITIIFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHF 222

Query: 205 DDDELWSLGKGVVVPTRFGN 224
           D DE W+LG     P   GN
Sbjct: 223 DSDEPWTLGN----PNHDGN 238



 Score =  109 bits (273), Expect = 8e-24
 Identities = 76/210 (36%), Positives = 105/210 (50%), Gaps = 28/210 (13%)

Query: 377 SNFDSDKKW--GFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRF--TEGPPLH 432
           ++FDSD+ W  G     G  LFLVA HE GHALGL+HS+ P A+M P Y++  T+   L 
Sbjct: 220 THFDSDEPWTLGNPNHDGNDLFLVAVHELGHALGLEHSNDPTAIMAPFYQYMETDNFKLP 279

Query: 433 KDDVNGIRHLYGPRPEPEPRPPTTTTPQPTAPP-TVCPTGPPTVHPSERPTAGPTGPPSA 491
            DD+ GI+ +YGP   P+  PP  T P PT PP    P   P  +   +P   PTG PS 
Sbjct: 280 NDDLQGIQKIYGP---PDKIPP-PTRPLPTVPPHRSIPPADPRKNDRPKPPRPPTGRPSY 335

Query: 492 GPTGPPTAGPSTATTVPLSPVDDACNVNIFDAIAEIGNQLYLFKDGKYWRFSEGRGSRPQ 551
                P A P            + C+ N F+ +A +  ++++FKD  +WR    R     
Sbjct: 336 -----PGAKP------------NICDGN-FNTLAILRREMFVFKDQWFWRVRNNR-VMDG 376

Query: 552 GPFLIADKWPALPRKLDSVFEERLSKKLFF 581
            P  I   W  LP  +D+V+E      +FF
Sbjct: 377 YPMQITYFWRGLPPSIDAVYENSDGNFVFF 406


>gi|112382270 matrix metalloproteinase 17 preproprotein [Homo
           sapiens]
          Length = 603

 Score =  120 bits (301), Expect = 4e-27
 Identities = 80/224 (35%), Positives = 105/224 (46%), Gaps = 32/224 (14%)

Query: 6   PLVLVLLVL-----GCCFAAPRQRQSTLVLFPGDLRTNLTDRQLAEEYLYRYGYTRVAE- 59
           PL L+LL+      GC   AP  R                D  L  E+L R+GY   A+ 
Sbjct: 22  PLPLLLLLALGTRGGCAAPAPAPRAE--------------DLSLGVEWLSRFGYLPPADP 67

Query: 60  ---MRGESKSLGPALLLLQKQLSLPETGELDSATLKAMRTPRCGVPDLG------RFQTF 110
                   + L  A+  +Q+   L  TG LD ATL  M+TPRC +PDL       R +  
Sbjct: 68  TTGQLQTQEELSKAITAMQQFGGLEATGILDEATLALMKTPRCSLPDLPVLTQARRRRQA 127

Query: 111 EGDLKWHHHNITYWIQNYSEDLPRA--VIDDAFARAFALWSAVTPLTFTRVYSRDADIVI 168
               KW+  N+++ ++ +  D P     +      A  +WS + PL F  V    ADI I
Sbjct: 128 PAPTKWNKRNLSWRVRTFPRDSPLGHDTVRALMYYALKVWSDIAPLNFHEVAGSAADIQI 187

Query: 169 QFGVAEHGDGYPFDGKDGLLAHAFPPG-PGIQGDAHFDDDELWS 211
            F  A+H DGYPFDG  G +AHAF PG     GD HFDDDE W+
Sbjct: 188 DFSKADHNDGYPFDGPGGTVAHAFFPGHHHTAGDTHFDDDEAWT 231



 Score =  106 bits (265), Expect = 6e-23
 Identities = 91/324 (28%), Positives = 134/324 (41%), Gaps = 56/324 (17%)

Query: 374 ATTSNFDSDKKWGFCPDQ--GYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTEGPPL 431
           A  ++FD D+ W F      G  LF VA HEFGHA+GL H +   ++M P Y+   G PL
Sbjct: 219 AGDTHFDDDEAWTFRSSDAHGMDLFAVAVHEFGHAIGLSHVAAAHSIMRPYYQGPVGDPL 278

Query: 432 H----KDDVNGIRHLYGPRPEPEPRPPTTTTPQPTAPPTVCPTGPPTVHPSERPTAGPTG 487
                 +D   +  LYG R    P      T QP  PP +                    
Sbjct: 279 RYGLPYEDKVRVWQLYGVRESVSP------TAQPEEPPLL------------------PE 314

Query: 488 PPSAGPTGPPTAGPSTATTVPLSPVDDACNVNIFDAIAEIGNQLYLFKDGKYWRFSEGRG 547
           PP    + PP              V   C+ + FDA+A+I  + + FK   +WR +  R 
Sbjct: 315 PPDNRSSAPPR-----------KDVPHRCSTH-FDAVAQIRGEAFFFKGKYFWRLTRDRH 362

Query: 548 SRPQGPFLIADKWPALPRKLDS---VFEERLSKKLFFFSGRQVWVYTGASVLG--PRRLD 602
                P  +   W  LP  LDS   V+E     K+ FF G + WV+   +V    PR + 
Sbjct: 363 LVSLQPAQMHRFWRGLPLHLDSVDAVYERTSDHKIVFFKGDRYWVFKDNNVEEGYPRPVS 422

Query: 603 KLGL---GADVAQVTGALRSGRGKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVPL 659
              L   G D A       +   +   F  +  WR+D   + +DP   ++   ++ GVP 
Sbjct: 423 DFSLPPGGIDAA----FSWAHNDRTYFFKDQLYWRYDDHTRHMDPGYPAQ-SPLWRGVPS 477

Query: 660 DTHDVFQYREKA-YFCQDRFYWRV 682
              D  ++ + A YF + + YW+V
Sbjct: 478 TLDDAMRWSDGASYFFRGQEYWKV 501


>gi|12408682 epididymal sperm binding protein 1 [Homo sapiens]
          Length = 223

 Score =  119 bits (298), Expect = 1e-26
 Identities = 58/163 (35%), Positives = 84/163 (51%), Gaps = 9/163 (5%)

Query: 226 DGAACHFPFIFEGRSYSACTTDGRSDGLPWCSTTANYDTDDRFGFCPSERLYTQDGNADG 285
           D   C FPFI+ G++Y++C + G   G  WCS T+ +D   ++ FC +       GN+  
Sbjct: 70  DYPRCIFPFIYRGKAYNSCISQGSFLGSLWCSVTSVFDEKQQWKFCETNEY---GGNSLR 126

Query: 286 KPCQFPFIFQGQSYSACTTDGRSDGYRWCATTANYDRDKLFGFCPTRADSTVMGGNSAGE 345
           KPC FP I++    S C  D       WC TT N D+D  + FC     S ++ G     
Sbjct: 127 KPCIFPSIYRNNVVSDCMED--ESNKLWCPTTENMDKDGKWSFCADTRISALVPGFP--- 181

Query: 346 LCVFPFTFLGKEYSTCTSEGRGDGRLWCATTSNFDSDKKWGFC 388
            C FPF +  K Y  CT++G  +  +WCAT+ N+D D  W +C
Sbjct: 182 -CHFPFNYKNKNYFNCTNKGSKENLVWCATSYNYDQDHTWVYC 223



 Score =  107 bits (268), Expect = 3e-23
 Identities = 57/161 (35%), Positives = 81/161 (50%), Gaps = 19/161 (11%)

Query: 230 CHFPFIFEGRSYSACTTDGRSDGLPWCSTTANYDTDDRFGFCPSERLYTQDGNADGKPCQ 289
           C FPF ++G  Y  CT        PWC+T A Y+   ++ +C SE         D   C 
Sbjct: 29  CVFPFTYKGSVYFTCTHIHSLS--PWCATRAVYN--GQWKYCQSE---------DYPRCI 75

Query: 290 FPFIFQGQSYSACTTDGRSDGYRWCATTANYDRDKLFGFCPTRADSTVMGGNSAGELCVF 349
           FPFI++G++Y++C + G   G  WC+ T+ +D  + + FC T       GGNS  + C+F
Sbjct: 76  FPFIYRGKAYNSCISQGSFLGSLWCSVTSVFDEKQQWKFCETNE----YGGNSLRKPCIF 131

Query: 350 PFTFLGKEYSTCTSEGRGDGRLWCATTSNFDSDKKWGFCPD 390
           P  +     S C  +     +LWC TT N D D KW FC D
Sbjct: 132 PSIYRNNVVSDCMEDE--SNKLWCPTTENMDKDGKWSFCAD 170



 Score = 79.7 bits (195), Expect = 8e-15
 Identities = 44/126 (34%), Positives = 61/126 (48%), Gaps = 8/126 (6%)

Query: 204 FDDDELWSLGKGVVVPTRFGNADGAACHFPFIFEGRSYSACTTDGRSDGLPWCSTTANYD 263
           FD+ + W   K        GN+    C FP I+     S C  D  S+ L WC TT N D
Sbjct: 106 FDEKQQW---KFCETNEYGGNSLRKPCIFPSIYRNNVVSDCMED-ESNKL-WCPTTENMD 160

Query: 264 TDDRFGFCPSERLYTQDGNADGKPCQFPFIFQGQSYSACTTDGRSDGYRWCATTANYDRD 323
            D ++ FC   R+        G PC FPF ++ ++Y  CT  G  +   WCAT+ NYD+D
Sbjct: 161 KDGKWSFCADTRI---SALVPGFPCHFPFNYKNKNYFNCTNKGSKENLVWCATSYNYDQD 217

Query: 324 KLFGFC 329
             + +C
Sbjct: 218 HTWVYC 223



 Score = 70.1 bits (170), Expect = 7e-12
 Identities = 37/106 (34%), Positives = 51/106 (48%), Gaps = 14/106 (13%)

Query: 288 CQFPFIFQGQSYSACTTDGRSDGYRWCATTANYDRDKLFGFCPTRADSTVMGGNSAGELC 347
           C FPF ++G  Y  CT         WCAT A Y+    + +C +               C
Sbjct: 29  CVFPFTYKGSVYFTCTHIHSLSP--WCATRAVYNGQ--WKYCQSEDYPR----------C 74

Query: 348 VFPFTFLGKEYSTCTSEGRGDGRLWCATTSNFDSDKKWGFCPDQGY 393
           +FPF + GK Y++C S+G   G LWC+ TS FD  ++W FC    Y
Sbjct: 75  IFPFIYRGKAYNSCISQGSFLGSLWCSVTSVFDEKQQWKFCETNEY 120



 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 25/70 (35%), Positives = 35/70 (50%), Gaps = 5/70 (7%)

Query: 203 HFDDDELWSLGKGVVVPTRFGN-ADGAACHFPFIFEGRSYSACTTDGRSDGLPWCSTTAN 261
           + D D  WS        TR      G  CHFPF ++ ++Y  CT  G  + L WC+T+ N
Sbjct: 158 NMDKDGKWSF----CADTRISALVPGFPCHFPFNYKNKNYFNCTNKGSKENLVWCATSYN 213

Query: 262 YDTDDRFGFC 271
           YD D  + +C
Sbjct: 214 YDQDHTWVYC 223


>gi|73808266 matrix metalloproteinase 26 preproprotein [Homo
           sapiens]
          Length = 261

 Score =  112 bits (279), Expect = 2e-24
 Identities = 57/138 (41%), Positives = 73/138 (52%)

Query: 74  LQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFQTFEGDLKWHHHNITYWIQNYSEDLP 133
           L +Q     T  LD      +  P CGVPD        G  KW+ H +TY I NY  D+ 
Sbjct: 57  LLQQFHRNGTDLLDMQMHALLHQPHCGVPDGSDTSISPGRCKWNKHTLTYRIINYPHDMK 116

Query: 134 RAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFP 193
            + + D+   A ++WS VTPL F +V + DADI + F    H DG+PFDG  G+L HAF 
Sbjct: 117 PSAVKDSIYNAVSIWSNVTPLIFQQVQNGDADIKVSFWQWAHEDGWPFDGPGGILGHAFL 176

Query: 194 PGPGIQGDAHFDDDELWS 211
           P  G  G  HFD +E WS
Sbjct: 177 PNSGNPGVVHFDKNEHWS 194



 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 32/71 (45%), Positives = 44/71 (61%), Gaps = 3/71 (4%)

Query: 378 NFDSDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTEGP--PLHKDD 435
           +FD ++ W    D GY+LFLVA HE GH+LGL HS    ++MYP Y + +     L  DD
Sbjct: 186 HFDKNEHWS-ASDTGYNLFLVATHEIGHSLGLQHSGNQSSIMYPTYWYHDPRTFQLSADD 244

Query: 436 VNGIRHLYGPR 446
           +  I+HLYG +
Sbjct: 245 IQRIQHLYGEK 255


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.139    0.454 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,413,868
Number of Sequences: 37866
Number of extensions: 1969904
Number of successful extensions: 26432
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 407
Number of HSP's successfully gapped in prelim test: 635
Number of HSP's that attempted gapping in prelim test: 12056
Number of HSP's gapped (non-prelim): 8670
length of query: 707
length of database: 18,247,518
effective HSP length: 109
effective length of query: 598
effective length of database: 14,120,124
effective search space: 8443834152
effective search space used: 8443834152
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.