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Search of human proteins with 73765544
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|73765544 phosphatase and tensin homolog [Homo sapiens]
(403 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|73765544 phosphatase and tensin homolog [Homo sapiens] 845 0.0
gi|213972593 TPTE and PTEN homologous inositol lipid phosphatase... 221 7e-58
gi|213972591 TPTE and PTEN homologous inositol lipid phosphatase... 221 7e-58
gi|213972589 TPTE and PTEN homologous inositol lipid phosphatase... 221 7e-58
gi|40549435 transmembrane phosphatase with tensin homology isofo... 206 4e-53
gi|40549433 transmembrane phosphatase with tensin homology isofo... 206 4e-53
gi|109689707 transmembrane phosphatase with tensin homology isof... 206 4e-53
gi|65288071 tensin 3 [Homo sapiens] 145 5e-35
gi|66529407 tensin [Homo sapiens] 142 5e-34
gi|38787970 tensin like C1 domain containing phosphatase isoform... 129 4e-30
gi|38787957 tensin like C1 domain containing phosphatase isoform... 129 4e-30
gi|38787941 tensin like C1 domain containing phosphatase isoform... 129 4e-30
gi|157384971 cyclin G associated kinase [Homo sapiens] 116 3e-26
gi|7662146 DnaJ (Hsp40) homolog, subfamily C, member 6 [Homo sap... 109 4e-24
gi|239756009 PREDICTED: similar to transmembrane phosphoinositid... 53 6e-07
gi|4506283 protein tyrosine phosphatase type IVA, member 1 [Homo... 44 3e-04
gi|18104971 protein tyrosine phosphatase type IVA, member 2 isof... 43 4e-04
gi|116008458 CDC14 homolog B isoform 3 [Homo sapiens] 42 8e-04
gi|4502699 CDC14 homolog B isoform 1 [Homo sapiens] 42 8e-04
gi|15451936 CDC14 homolog B isoform 2 [Homo sapiens] 42 8e-04
gi|15451933 CDC14 homolog A isoform 3 [Homo sapiens] 42 0.001
gi|15451929 CDC14 homolog A isoform 1 [Homo sapiens] 42 0.001
gi|15451931 CDC14 homolog A isoform 2 [Homo sapiens] 42 0.001
gi|14589856 protein tyrosine phosphatase type IVA, member 3 isof... 42 0.001
gi|241896926 protein tyrosine phosphatase, receptor type, H isof... 39 0.006
gi|241896924 protein tyrosine phosphatase, receptor type, H isof... 39 0.006
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 37 0.024
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 37 0.024
gi|18450371 protein tyrosine phosphatase, receptor type, A isofo... 37 0.024
gi|4506303 protein tyrosine phosphatase, receptor type, A isofor... 37 0.024
>gi|73765544 phosphatase and tensin homolog [Homo sapiens]
Length = 403
Score = 845 bits (2184), Expect = 0.0
Identities = 403/403 (100%), Positives = 403/403 (100%)
Query: 1 MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSK 60
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSK
Sbjct: 1 MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSK 60
Query: 61 HKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVA 120
HKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVA
Sbjct: 61 HKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVA 120
Query: 121 AIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSY 180
AIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSY
Sbjct: 121 AIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSY 180
Query: 181 LLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMY 240
LLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMY
Sbjct: 181 LLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMY 240
Query: 241 FEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEI 300
FEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEI
Sbjct: 241 FEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEI 300
Query: 301 DSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEAS 360
DSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEAS
Sbjct: 301 DSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEAS 360
Query: 361 SSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV 403
SSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV
Sbjct: 361 SSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV 403
>gi|213972593 TPTE and PTEN homologous inositol lipid phosphatase
isoform delta [Homo sapiens]
Length = 411
Score = 221 bits (564), Expect = 7e-58
Identities = 133/358 (37%), Positives = 191/358 (53%), Gaps = 52/358 (14%)
Query: 4 IIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKN 63
+++ +VS NKRRY DGFDLDLTY+ IIAM FP+ + YRN I++VVRFLD KH+N
Sbjct: 89 LMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRN 148
Query: 64 HYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIH 123
HY++YNLC+ER YD F+ RV++ +DHN P L + F +++++W+++D ++ AIH
Sbjct: 149 HYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIH 208
Query: 124 CKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDK-----KGVTIPSQRRYVYYY 178
CK GKGRTG M+CA L+ FL A+E+L ++GE RT +GV PSQ RYV Y+
Sbjct: 209 CKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYF 268
Query: 179 SYLLKNHL---DYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPT--- 232
+ + HL + P +LF K I G C+ + V K ++SS S
Sbjct: 269 AQV--KHLYNWNLPPRRILFIKRFI--IYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSI 324
Query: 233 ---RREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEK 289
DK + + P P+ D+KV+FF + F FW NT FI
Sbjct: 325 LHDIETDKILINVYDGP-PLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFI--------- 374
Query: 290 VENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYF 347
+N LC L +N+LD +K KA + + P F V++ F
Sbjct: 375 -QNNRLC-----------------------LPRNELDNPHKQKAWKIYPPEFAVEILF 408
>gi|213972591 TPTE and PTEN homologous inositol lipid phosphatase
isoform gamma [Homo sapiens]
Length = 522
Score = 221 bits (564), Expect = 7e-58
Identities = 133/358 (37%), Positives = 191/358 (53%), Gaps = 52/358 (14%)
Query: 4 IIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKN 63
+++ +VS NKRRY DGFDLDLTY+ IIAM FP+ + YRN I++VVRFLD KH+N
Sbjct: 200 LMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRN 259
Query: 64 HYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIH 123
HY++YNLC+ER YD F+ RV++ +DHN P L + F +++++W+++D ++ AIH
Sbjct: 260 HYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIH 319
Query: 124 CKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDK-----KGVTIPSQRRYVYYY 178
CK GKGRTG M+CA L+ FL A+E+L ++GE RT +GV PSQ RYV Y+
Sbjct: 320 CKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYF 379
Query: 179 SYLLKNHL---DYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPT--- 232
+ + HL + P +LF K I G C+ + V K ++SS S
Sbjct: 380 AQV--KHLYNWNLPPRRILFIKRFI--IYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSI 435
Query: 233 ---RREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEK 289
DK + + P P+ D+KV+FF + F FW NT FI
Sbjct: 436 LHDIETDKILINVYDGP-PLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFI--------- 485
Query: 290 VENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYF 347
+N LC L +N+LD +K KA + + P F V++ F
Sbjct: 486 -QNNRLC-----------------------LPRNELDNPHKQKAWKIYPPEFAVEILF 519
>gi|213972589 TPTE and PTEN homologous inositol lipid phosphatase
isoform alpha [Homo sapiens]
Length = 445
Score = 221 bits (564), Expect = 7e-58
Identities = 133/358 (37%), Positives = 191/358 (53%), Gaps = 52/358 (14%)
Query: 4 IIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKN 63
+++ +VS NKRRY DGFDLDLTY+ IIAM FP+ + YRN I++VVRFLD KH+N
Sbjct: 123 LMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRN 182
Query: 64 HYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIH 123
HY++YNLC+ER YD F+ RV++ +DHN P L + F +++++W+++D ++ AIH
Sbjct: 183 HYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIH 242
Query: 124 CKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDK-----KGVTIPSQRRYVYYY 178
CK GKGRTG M+CA L+ FL A+E+L ++GE RT +GV PSQ RYV Y+
Sbjct: 243 CKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYF 302
Query: 179 SYLLKNHL---DYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPT--- 232
+ + HL + P +LF K I G C+ + V K ++SS S
Sbjct: 303 AQV--KHLYNWNLPPRRILFIKRFI--IYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSI 358
Query: 233 ---RREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEK 289
DK + + P P+ D+KV+FF + F FW NT FI
Sbjct: 359 LHDIETDKILINVYDGP-PLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFI--------- 408
Query: 290 VENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYF 347
+N LC L +N+LD +K KA + + P F V++ F
Sbjct: 409 -QNNRLC-----------------------LPRNELDNPHKQKAWKIYPPEFAVEILF 442
>gi|40549435 transmembrane phosphatase with tensin homology isoform
gamma [Homo sapiens]
Length = 513
Score = 206 bits (523), Expect = 4e-53
Identities = 126/360 (35%), Positives = 194/360 (53%), Gaps = 56/360 (15%)
Query: 4 IIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKN 63
+I+ VS NKRRY DGFDLDLTY+ IIAM FP+ + YRN I +VVRFLD KH+N
Sbjct: 180 LIRRRVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRN 239
Query: 64 HYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIH 123
HY++YNLC+ER YD F+ RV + +DHN P L + F +++++W+++D ++ AIH
Sbjct: 240 HYRVYNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIH 299
Query: 124 CKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDK------KGVTIPSQRRYVYY 177
CK G RTG M+CA+L+ A+E+L ++GE RT DK +GV PSQ+RYV Y
Sbjct: 300 CKGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRT-DKTHSEKFQGVETPSQKRYVAY 358
Query: 178 YS---YLLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTR- 233
++ +L +L R + + H +++ +IP + + +++ K+ S +
Sbjct: 359 FAQVKHLYNWNLPPRRILFIKHFIIY-SIPRY----VRDLKIQIEMEKKVVFSTISLGKC 413
Query: 234 ------REDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETS 287
DK + F LP+ D+KV+FF+ + F+FW++T FI
Sbjct: 414 SVLDNITTDKILIDVF-DGLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFI------- 465
Query: 288 EKVENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYF 347
+N++ Y L KN+LD +K KA R + +F V++ F
Sbjct: 466 ----------------------ENNRLY----LPKNELDNLHKQKARRIYPSDFAVEILF 499
>gi|40549433 transmembrane phosphatase with tensin homology isoform
beta [Homo sapiens]
Length = 533
Score = 206 bits (523), Expect = 4e-53
Identities = 126/360 (35%), Positives = 194/360 (53%), Gaps = 56/360 (15%)
Query: 4 IIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKN 63
+I+ VS NKRRY DGFDLDLTY+ IIAM FP+ + YRN I +VVRFLD KH+N
Sbjct: 200 LIRRRVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRN 259
Query: 64 HYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIH 123
HY++YNLC+ER YD F+ RV + +DHN P L + F +++++W+++D ++ AIH
Sbjct: 260 HYRVYNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIH 319
Query: 124 CKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDK------KGVTIPSQRRYVYY 177
CK G RTG M+CA+L+ A+E+L ++GE RT DK +GV PSQ+RYV Y
Sbjct: 320 CKGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRT-DKTHSEKFQGVETPSQKRYVAY 378
Query: 178 YS---YLLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTR- 233
++ +L +L R + + H +++ +IP + + +++ K+ S +
Sbjct: 379 FAQVKHLYNWNLPPRRILFIKHFIIY-SIPRY----VRDLKIQIEMEKKVVFSTISLGKC 433
Query: 234 ------REDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETS 287
DK + F LP+ D+KV+FF+ + F+FW++T FI
Sbjct: 434 SVLDNITTDKILIDVF-DGLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFI------- 485
Query: 288 EKVENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYF 347
+N++ Y L KN+LD +K KA R + +F V++ F
Sbjct: 486 ----------------------ENNRLY----LPKNELDNLHKQKARRIYPSDFAVEILF 519
>gi|109689707 transmembrane phosphatase with tensin homology isoform
alpha [Homo sapiens]
Length = 551
Score = 206 bits (523), Expect = 4e-53
Identities = 126/360 (35%), Positives = 194/360 (53%), Gaps = 56/360 (15%)
Query: 4 IIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKN 63
+I+ VS NKRRY DGFDLDLTY+ IIAM FP+ + YRN I +VVRFLD KH+N
Sbjct: 218 LIRRRVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRN 277
Query: 64 HYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIH 123
HY++YNLC+ER YD F+ RV + +DHN P L + F +++++W+++D ++ AIH
Sbjct: 278 HYRVYNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIH 337
Query: 124 CKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDK------KGVTIPSQRRYVYY 177
CK G RTG M+CA+L+ A+E+L ++GE RT DK +GV PSQ+RYV Y
Sbjct: 338 CKGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRT-DKTHSEKFQGVETPSQKRYVAY 396
Query: 178 YS---YLLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTR- 233
++ +L +L R + + H +++ +IP + + +++ K+ S +
Sbjct: 397 FAQVKHLYNWNLPPRRILFIKHFIIY-SIPRY----VRDLKIQIEMEKKVVFSTISLGKC 451
Query: 234 ------REDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETS 287
DK + F LP+ D+KV+FF+ + F+FW++T FI
Sbjct: 452 SVLDNITTDKILIDVF-DGLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFI------- 503
Query: 288 EKVENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYF 347
+N++ Y L KN+LD +K KA R + +F V++ F
Sbjct: 504 ----------------------ENNRLY----LPKNELDNLHKQKARRIYPSDFAVEILF 537
>gi|65288071 tensin 3 [Homo sapiens]
Length = 1445
Score = 145 bits (367), Expect = 5e-35
Identities = 106/347 (30%), Positives = 158/347 (45%), Gaps = 45/347 (12%)
Query: 18 EDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYD 77
E+G LDLTYI IIA+ FPA E Y +N+ +V R L SKH ++Y + NL +E+ YD
Sbjct: 2 EEGHGLDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNYLVLNL-SEKRYD 60
Query: 78 TAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICA 137
K N ++ + + + P L+ + C+ + WL+ + HV IHC+ GKGR GV+I +
Sbjct: 61 LTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIGVVISS 120
Query: 138 YLLHRGKFLKAQEALDFYGEVRTRDKK--GVTIPSQRRYVYYYSYLLKNHLDYRPVALLF 195
Y+ A +ALD + + D K + PSQ+RYV + S LL + L
Sbjct: 121 YMHFTNVSASADQALDRFAMKKFYDDKVSALMQPSQKRYVQFLSGLLSGSVKMNASPLFL 180
Query: 196 HKMMFETIPMF-SGGTCNPQFVVCQLKVKIYSS---NSGPTRREDKFMYFEFPQPLPVCG 251
H ++ P F +GG C P + Q +Y+S N GP + E Q L G
Sbjct: 181 HFVILHGTPNFDTGGVCRPFLKLYQAMQPVYTSGIYNVGPENPSRICIVIEPAQLLK--G 238
Query: 252 DIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADN 311
D+ V+ +HK+ + +D +F +T + G
Sbjct: 239 DVMVKCYHKKYRSATRDVIFRLQFHTGAVQG----------------------------- 269
Query: 312 DKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPE 358
L K DLD A+KD F KV+L F+ T E+ E
Sbjct: 270 ----YGLVFGKEDLDNASKDDR---FPDYGKVELVFSATPEKIQGSE 309
>gi|66529407 tensin [Homo sapiens]
Length = 1735
Score = 142 bits (358), Expect = 5e-34
Identities = 89/267 (33%), Positives = 141/267 (52%), Gaps = 5/267 (1%)
Query: 15 RYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAER 74
R ED +LDL Y+ IIA+ FP+ E +R+N+ +V + L SKH +Y ++NL +ER
Sbjct: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL-SER 63
Query: 75 HYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVM 134
D K + +V ++ + D + P LE I C+ +D WL+ D ++V +H K +GR GV+
Sbjct: 64 RPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVV 123
Query: 135 ICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTI--PSQRRYVYYYSYLLKNHLDYRPVA 192
I AY+ + A +ALD + R + K V I PSQRRYV+Y+S LL +
Sbjct: 124 IAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMNNKP 183
Query: 193 LLFHKMMFETIPMF-SGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQP-LPVC 250
L H ++ IP F S G C P + Q +Y+S + + +P L +
Sbjct: 184 LFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGLLLK 243
Query: 251 GDIKVEFFHKQNKMLKKDKMFHFWVNT 277
GDI ++ +HK+ + +D +F +T
Sbjct: 244 GDILLKCYHKKFRSPARDVIFRVQFHT 270
>gi|38787970 tensin like C1 domain containing phosphatase isoform 3
[Homo sapiens]
Length = 1285
Score = 129 bits (325), Expect = 4e-30
Identities = 83/279 (29%), Positives = 138/279 (49%), Gaps = 11/279 (3%)
Query: 18 EDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYD 77
E +DLDLTY+ I+A FPA E +R ++ ++ L SKH++ Y ++NL +RH D
Sbjct: 2 ERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRH-D 60
Query: 78 TAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICA 137
+ N +V + + + + P L+ + C+ ++ WLS D HV ++CK KG+ GV++ A
Sbjct: 61 LTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSA 120
Query: 138 YLLHRGKFLKAQEALDFYGEVRTRDKKGVT--IPSQRRYVYYYSYLLKNHLDYRPVALLF 195
Y+ + A +AL + + K T PSQRRY+ Y+S LL + L
Sbjct: 121 YMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSPLFL 180
Query: 196 HKMMFETIPMFSGGT-CNPQFVVCQLKVKIYSSN----SGPTRREDKFMYFEFPQPLPVC 250
H ++ +P F GT P + Q +Y+S +GP ++ + L +
Sbjct: 181 HYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQ---LCISLEPALLLK 237
Query: 251 GDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEK 289
GD+ V +HK + + +F +T I GP+ T K
Sbjct: 238 GDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPK 276
>gi|38787957 tensin like C1 domain containing phosphatase isoform 2
[Homo sapiens]
Length = 1409
Score = 129 bits (325), Expect = 4e-30
Identities = 83/279 (29%), Positives = 138/279 (49%), Gaps = 11/279 (3%)
Query: 18 EDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYD 77
E +DLDLTY+ I+A FPA E +R ++ ++ L SKH++ Y ++NL +RH D
Sbjct: 126 ERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRH-D 184
Query: 78 TAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICA 137
+ N +V + + + + P L+ + C+ ++ WLS D HV ++CK KG+ GV++ A
Sbjct: 185 LTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSA 244
Query: 138 YLLHRGKFLKAQEALDFYGEVRTRDKKGVT--IPSQRRYVYYYSYLLKNHLDYRPVALLF 195
Y+ + A +AL + + K T PSQRRY+ Y+S LL + L
Sbjct: 245 YMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSPLFL 304
Query: 196 HKMMFETIPMFSGGT-CNPQFVVCQLKVKIYSSN----SGPTRREDKFMYFEFPQPLPVC 250
H ++ +P F GT P + Q +Y+S +GP ++ + L +
Sbjct: 305 HYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQ---LCISLEPALLLK 361
Query: 251 GDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEK 289
GD+ V +HK + + +F +T I GP+ T K
Sbjct: 362 GDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPK 400
>gi|38787941 tensin like C1 domain containing phosphatase isoform 1
[Homo sapiens]
Length = 1419
Score = 129 bits (325), Expect = 4e-30
Identities = 83/279 (29%), Positives = 138/279 (49%), Gaps = 11/279 (3%)
Query: 18 EDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYD 77
E +DLDLTY+ I+A FPA E +R ++ ++ L SKH++ Y ++NL +RH D
Sbjct: 136 ERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRH-D 194
Query: 78 TAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICA 137
+ N +V + + + + P L+ + C+ ++ WLS D HV ++CK KG+ GV++ A
Sbjct: 195 LTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSA 254
Query: 138 YLLHRGKFLKAQEALDFYGEVRTRDKKGVT--IPSQRRYVYYYSYLLKNHLDYRPVALLF 195
Y+ + A +AL + + K T PSQRRY+ Y+S LL + L
Sbjct: 255 YMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSPLFL 314
Query: 196 HKMMFETIPMFSGGT-CNPQFVVCQLKVKIYSSN----SGPTRREDKFMYFEFPQPLPVC 250
H ++ +P F GT P + Q +Y+S +GP ++ + L +
Sbjct: 315 HYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQ---LCISLEPALLLK 371
Query: 251 GDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEK 289
GD+ V +HK + + +F +T I GP+ T K
Sbjct: 372 GDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPK 410
>gi|157384971 cyclin G associated kinase [Homo sapiens]
Length = 1311
Score = 116 bits (291), Expect = 3e-26
Identities = 94/394 (23%), Positives = 168/394 (42%), Gaps = 41/394 (10%)
Query: 22 DLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKF 81
DLD++YI I M FPAE +E +NNI+DV FLDSKH HY +YNL + R Y ++F
Sbjct: 407 DLDISYITSRIAVMSFPAEGVESALKNNIEDVRLFLDSKHPGHYAVYNL-SPRTYRPSRF 465
Query: 82 NCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLH 141
+ RV++ + P L + C ++ WL +D +V +HC G+ + V +C++L
Sbjct: 466 HNRVSECGWAARRAPHLHTLYNICRNMHAWLRQDHKNVCVVHCMDGRAASAVAVCSFLCF 525
Query: 142 RGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYV-YYYSYLLKNHLDYRPVALLFHKMMF 200
F A+ A+ + R G+ PS +RY+ Y + + + +L ++
Sbjct: 526 CRLFSTAEAAVYMFS--MKRCPPGIW-PSHKRYIEYMCDMVAEEPITPHSKPILVRAVVM 582
Query: 201 ETIPMFSGGTCNPQFVVCQLKVKIYSSN---SGPTRREDKFMYFE-------FPQPLPVC 250
+P+FS Q C+ ++Y + + ++ DK F+ P + V
Sbjct: 583 TPVPLFS-----KQRSGCRPFCEVYVGDERVASTSQEYDKMRDFKIEDGKAVIPLGVTVQ 637
Query: 251 GDIKVEFFHKQNKM-------LKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSI 303
GD+ + +H ++ + + KMF +T F+P T + +
Sbjct: 638 GDVLIVIYHARSTLGGRLQAKMASMKMFQIQFHTGFVPRNATTVKFAK------------ 685
Query: 304 CSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSP--NFKVKLYFTKTVEEPSNPEASS 361
++ D ++Y L +++ +D+ +R P N ++ K + +
Sbjct: 686 YDLDACDIQEKYPDLFQVNLEVEVEPRDRPSREAPPWENSSMRGLNPKILFSSREEQQDI 745
Query: 362 STSVTPDVSDNEPDHYRYSDTTDSDPENEPFDED 395
+ +P D PE EP D D
Sbjct: 746 LSKFGKPELPRQPGSTAQYDAGAGSPEAEPTDSD 779
>gi|7662146 DnaJ (Hsp40) homolog, subfamily C, member 6 [Homo
sapiens]
Length = 913
Score = 109 bits (273), Expect = 4e-24
Identities = 77/275 (28%), Positives = 132/275 (48%), Gaps = 21/275 (7%)
Query: 22 DLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKF 81
DLD TY+ II M FP + ++ +RN +DD+ FLDS+H +HY +YNL + + Y TAKF
Sbjct: 63 DLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVYNL-SPKSYRTAKF 121
Query: 82 NCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLH 141
+ RV++ + P L + C ++ WL ++ +V +HC G+ + +++ A +
Sbjct: 122 HSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIF 181
Query: 142 RGKFLKAQEALDFYGEVRTRDKKGVTI-PSQRRYVYYYSYLLKNHLDYRP--VALLFHKM 198
+ A+ + + G+ + PS RRY+ Y LL + YRP L +
Sbjct: 182 CNLYSTPGPAI----RLLYAKRPGIGLSPSHRRYLGYMCDLLADK-PYRPHFKPLTIKSI 236
Query: 199 MFETIPMFS--GGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMY---FEFPQPLPVCGDI 253
IP F+ C P V + KIYS+ + R ++ + P + V GD+
Sbjct: 237 TVSPIPFFNKQRNGCRPYCDVLIGETKIYSTCTDFERMKEYRVQDGKIFIPLNITVQGDV 296
Query: 254 KVEFFHKQNKM-------LKKDKMFHFWVNTFFIP 281
V +H ++ + + ++F +T FIP
Sbjct: 297 VVSMYHLRSTIGSRLQAKVTNTQIFQLQFHTGFIP 331
>gi|239756009 PREDICTED: similar to transmembrane phosphoinositide
3-phosphatase and tensin homolog 2, partial [Homo
sapiens]
Length = 99
Score = 52.8 bits (125), Expect = 6e-07
Identities = 21/56 (37%), Positives = 35/56 (62%)
Query: 73 ERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGK 128
ER YD F+ RV++ +DHN P L + F +++ +W+++D ++ IHCK GK
Sbjct: 29 ERAYDPKHFHNRVSRIMIDDHNVPTLREMVAFSKEVLEWMAQDSENIVVIHCKGGK 84
>gi|4506283 protein tyrosine phosphatase type IVA, member 1 [Homo
sapiens]
Length = 173
Score = 43.9 bits (102), Expect = 3e-04
Identities = 32/103 (31%), Positives = 48/103 (46%), Gaps = 20/103 (19%)
Query: 67 IYNLCAERHYDTA---KFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLS-------EDD 116
I +C E YDT K V +PF+D PP +++ D WLS E+
Sbjct: 45 IVRVC-EATYDTTLVEKEGIHVLDWPFDDGAPPSNQIV-------DDWLSLVKIKFREEP 96
Query: 117 NHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVR 159
A+HC AG GR V++ L+ G +K ++A+ F + R
Sbjct: 97 GCCIAVHCVAGLGRAPVLVALALIEGG--MKYEDAVQFIRQKR 137
>gi|18104971 protein tyrosine phosphatase type IVA, member 2 isoform
1 [Homo sapiens]
Length = 167
Score = 43.1 bits (100), Expect = 4e-04
Identities = 32/117 (27%), Positives = 54/117 (46%), Gaps = 11/117 (9%)
Query: 76 YDTA---KFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTG 132
YD A K V +PF+D PP +++ + L E+ A+HC AG GR
Sbjct: 50 YDKAPVEKEGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAP 109
Query: 133 VMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYR 189
V++ L+ G +K ++A+ F + R +G + ++ +Y Y K L +R
Sbjct: 110 VLVALALIECG--MKYEDAVQFIRQKR----RGAF--NSKQLLYLEKYRPKMRLRFR 158
>gi|116008458 CDC14 homolog B isoform 3 [Homo sapiens]
Length = 461
Score = 42.4 bits (98), Expect = 8e-04
Identities = 36/133 (27%), Positives = 62/133 (46%), Gaps = 15/133 (11%)
Query: 24 DLTYIYPN-IIAMGFPAERLE---GVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTA 79
DL +I P+ IA P R G ++++ + +++ K+ N I L +R YD
Sbjct: 178 DLNWIIPDRFIAFCGPHSRARLESGYHQHSPETYIQYF--KNHNVTTIIRL-NKRMYDAK 234
Query: 80 KFNCRVAQYP---FEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMIC 136
+F + F D + P ++K F + + E+ A+HCKAG GRTG +I
Sbjct: 235 RFTDAGFDHHDLFFADGSTPTDAIVKEFLD-----ICENAEGAIAVHCKAGLGRTGTLIA 289
Query: 137 AYLLHRGKFLKAQ 149
Y++ + A+
Sbjct: 290 CYIMKHYRMTAAE 302
>gi|4502699 CDC14 homolog B isoform 1 [Homo sapiens]
Length = 459
Score = 42.4 bits (98), Expect = 8e-04
Identities = 36/133 (27%), Positives = 62/133 (46%), Gaps = 15/133 (11%)
Query: 24 DLTYIYPN-IIAMGFPAERLE---GVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTA 79
DL +I P+ IA P R G ++++ + +++ K+ N I L +R YD
Sbjct: 215 DLNWIIPDRFIAFCGPHSRARLESGYHQHSPETYIQYF--KNHNVTTIIRL-NKRMYDAK 271
Query: 80 KFNCRVAQYP---FEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMIC 136
+F + F D + P ++K F + + E+ A+HCKAG GRTG +I
Sbjct: 272 RFTDAGFDHHDLFFADGSTPTDAIVKEFLD-----ICENAEGAIAVHCKAGLGRTGTLIA 326
Query: 137 AYLLHRGKFLKAQ 149
Y++ + A+
Sbjct: 327 CYIMKHYRMTAAE 339
>gi|15451936 CDC14 homolog B isoform 2 [Homo sapiens]
Length = 498
Score = 42.4 bits (98), Expect = 8e-04
Identities = 36/133 (27%), Positives = 62/133 (46%), Gaps = 15/133 (11%)
Query: 24 DLTYIYPN-IIAMGFPAERLE---GVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTA 79
DL +I P+ IA P R G ++++ + +++ K+ N I L +R YD
Sbjct: 215 DLNWIIPDRFIAFCGPHSRARLESGYHQHSPETYIQYF--KNHNVTTIIRL-NKRMYDAK 271
Query: 80 KFNCRVAQYP---FEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMIC 136
+F + F D + P ++K F + + E+ A+HCKAG GRTG +I
Sbjct: 272 RFTDAGFDHHDLFFADGSTPTDAIVKEFLD-----ICENAEGAIAVHCKAGLGRTGTLIA 326
Query: 137 AYLLHRGKFLKAQ 149
Y++ + A+
Sbjct: 327 CYIMKHYRMTAAE 339
>gi|15451933 CDC14 homolog A isoform 3 [Homo sapiens]
Length = 383
Score = 41.6 bits (96), Expect = 0.001
Identities = 32/121 (26%), Positives = 51/121 (42%), Gaps = 21/121 (17%)
Query: 33 IAMGFPAERLEGVY----RNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQY 88
I G+P E + ++N+ VVR +K K + HYD
Sbjct: 200 IENGYPLHAPEAYFPYFKKHNVTAVVRL--NKKIYEAKRFTDAGFEHYDLF--------- 248
Query: 89 PFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKA 148
F D + P +++ F + E+ A+HCKAG GRTG +I Y++ +F A
Sbjct: 249 -FIDGSTPSDNIVRRFLN-----ICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHA 302
Query: 149 Q 149
+
Sbjct: 303 E 303
>gi|15451929 CDC14 homolog A isoform 1 [Homo sapiens]
Length = 594
Score = 41.6 bits (96), Expect = 0.001
Identities = 32/121 (26%), Positives = 51/121 (42%), Gaps = 21/121 (17%)
Query: 33 IAMGFPAERLEGVY----RNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQY 88
I G+P E + ++N+ VVR +K K + HYD
Sbjct: 200 IENGYPLHAPEAYFPYFKKHNVTAVVRL--NKKIYEAKRFTDAGFEHYDLF--------- 248
Query: 89 PFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKA 148
F D + P +++ F + E+ A+HCKAG GRTG +I Y++ +F A
Sbjct: 249 -FIDGSTPSDNIVRRFLN-----ICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHA 302
Query: 149 Q 149
+
Sbjct: 303 E 303
>gi|15451931 CDC14 homolog A isoform 2 [Homo sapiens]
Length = 623
Score = 41.6 bits (96), Expect = 0.001
Identities = 32/121 (26%), Positives = 51/121 (42%), Gaps = 21/121 (17%)
Query: 33 IAMGFPAERLEGVY----RNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQY 88
I G+P E + ++N+ VVR +K K + HYD
Sbjct: 200 IENGYPLHAPEAYFPYFKKHNVTAVVRL--NKKIYEAKRFTDAGFEHYDLF--------- 248
Query: 89 PFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKA 148
F D + P +++ F + E+ A+HCKAG GRTG +I Y++ +F A
Sbjct: 249 -FIDGSTPSDNIVRRFLN-----ICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHA 302
Query: 149 Q 149
+
Sbjct: 303 E 303
>gi|14589856 protein tyrosine phosphatase type IVA, member 3 isoform
1 [Homo sapiens]
Length = 173
Score = 41.6 bits (96), Expect = 0.001
Identities = 28/105 (26%), Positives = 49/105 (46%), Gaps = 8/105 (7%)
Query: 85 VAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGK 144
V +PF+D PP ++++ + + E A+HC AG GR V++ L+ G
Sbjct: 65 VVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESG- 123
Query: 145 FLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYR 189
+K ++A+ F R K+ I S ++ Y Y K L ++
Sbjct: 124 -MKYEDAIQF-----IRQKRRGAINS-KQLTYLEKYRPKQRLRFK 161
>gi|241896926 protein tyrosine phosphatase, receptor type, H isoform
2 precursor [Homo sapiens]
Length = 937
Score = 39.3 bits (90), Expect = 0.006
Identities = 27/95 (28%), Positives = 49/95 (51%), Gaps = 5/95 (5%)
Query: 92 DHNPPQL-ELIKPFCEDLDQWLSED-DNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQ 149
DH P + + F L QWL + + +HC AG GRTG +I +L R L+++
Sbjct: 808 DHGVPSSPDTLLAFWRMLRQWLDQTMEGGPPIVHCSAGVGRTGTLIALDVLLRQ--LQSE 865
Query: 150 EALDFYGEVR-TRDKKGVTIPSQRRYVYYYSYLLK 183
L + VR R+ + + + ++ +YV+ + +L+
Sbjct: 866 GLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILR 900
>gi|241896924 protein tyrosine phosphatase, receptor type, H isoform 1
precursor [Homo sapiens]
Length = 1115
Score = 39.3 bits (90), Expect = 0.006
Identities = 27/95 (28%), Positives = 49/95 (51%), Gaps = 5/95 (5%)
Query: 92 DHNPPQL-ELIKPFCEDLDQWLSED-DNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQ 149
DH P + + F L QWL + + +HC AG GRTG +I +L R L+++
Sbjct: 986 DHGVPSSPDTLLAFWRMLRQWLDQTMEGGPPIVHCSAGVGRTGTLIALDVLLRQ--LQSE 1043
Query: 150 EALDFYGEVR-TRDKKGVTIPSQRRYVYYYSYLLK 183
L + VR R+ + + + ++ +YV+ + +L+
Sbjct: 1044 GLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILR 1078
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1
precursor [Homo sapiens]
Length = 1907
Score = 37.4 bits (85), Expect = 0.024
Identities = 31/119 (26%), Positives = 53/119 (44%), Gaps = 15/119 (12%)
Query: 122 IHCKAGKGRTGVMICA-YLLHRGKFLKAQEALDFYGEVR-TRDKKGVTIPSQRRYVYYYS 179
+HC AG GRTG I +L R +K ++ +D YG V R ++ + ++ +YV+ +
Sbjct: 1546 VHCSAGVGRTGCFIVIDAMLER---MKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHE 1602
Query: 180 YLLK----NHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRR 234
LL+ H + L H +P T +L+ K+ +S+ T R
Sbjct: 1603 ALLEAATCGHTEVPARNLYAHIQKLGQVPPGESVT------AMELEFKLLASSKAHTSR 1655
Score = 30.4 bits (67), Expect = 3.0
Identities = 19/64 (29%), Positives = 35/64 (54%), Gaps = 5/64 (7%)
Query: 122 IHCKAGKGRTGVMI-CAYLLHRGKFLKAQEALDFYGEVRT-RDKKGVTIPSQRRYVYYYS 179
+HC AG GRTGV I + +L R ++ + +D + V+T R ++ + ++ +Y Y
Sbjct: 1837 VHCSAGVGRTGVFITLSIVLER---MRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYR 1893
Query: 180 YLLK 183
L+
Sbjct: 1894 AALE 1897
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
precursor [Homo sapiens]
Length = 1898
Score = 37.4 bits (85), Expect = 0.024
Identities = 31/119 (26%), Positives = 53/119 (44%), Gaps = 15/119 (12%)
Query: 122 IHCKAGKGRTGVMICA-YLLHRGKFLKAQEALDFYGEVR-TRDKKGVTIPSQRRYVYYYS 179
+HC AG GRTG I +L R +K ++ +D YG V R ++ + ++ +YV+ +
Sbjct: 1537 VHCSAGVGRTGCFIVIDAMLER---MKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHE 1593
Query: 180 YLLK----NHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRR 234
LL+ H + L H +P T +L+ K+ +S+ T R
Sbjct: 1594 ALLEAATCGHTEVPARNLYAHIQKLGQVPPGESVT------AMELEFKLLASSKAHTSR 1646
Score = 30.4 bits (67), Expect = 3.0
Identities = 19/64 (29%), Positives = 35/64 (54%), Gaps = 5/64 (7%)
Query: 122 IHCKAGKGRTGVMI-CAYLLHRGKFLKAQEALDFYGEVRT-RDKKGVTIPSQRRYVYYYS 179
+HC AG GRTGV I + +L R ++ + +D + V+T R ++ + ++ +Y Y
Sbjct: 1828 VHCSAGVGRTGVFITLSIVLER---MRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYR 1884
Query: 180 YLLK 183
L+
Sbjct: 1885 AALE 1888
>gi|18450371 protein tyrosine phosphatase, receptor type, A isoform
2 precursor [Homo sapiens]
Length = 793
Score = 37.4 bits (85), Expect = 0.024
Identities = 24/68 (35%), Positives = 38/68 (55%), Gaps = 7/68 (10%)
Query: 122 IHCKAGKGRTG--VMICAYLLHRGKFLKAQEALDFYGEV-RTRDKKGVTIPSQRRYVYYY 178
+HC AG GRTG V+I A L + + +D YG V R R ++ + + +YV+ Y
Sbjct: 431 VHCSAGVGRTGTFVVIDAML----DMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIY 486
Query: 179 SYLLKNHL 186
LL+++L
Sbjct: 487 QALLEHYL 494
Score = 32.7 bits (73), Expect = 0.60
Identities = 23/77 (29%), Positives = 42/77 (54%), Gaps = 8/77 (10%)
Query: 114 EDDNHVAAIHCKAGKGRTGVMICAY--LLHRGKFLKAQEALDFYGEVRT-RDKKGVTIPS 170
+ NH +HC AG GRTG CA +L R +KA+ LD + V++ R ++ + +
Sbjct: 713 QSGNHPITVHCSAGAGRTGT-FCALSTVLER---VKAEGILDVFQTVKSLRLQRPHMVQT 768
Query: 171 QRRYVYYYSYLLKNHLD 187
+Y + Y +++ ++D
Sbjct: 769 LEQYEFCYK-VVQEYID 784
>gi|4506303 protein tyrosine phosphatase, receptor type, A isoform 1
precursor [Homo sapiens]
Length = 802
Score = 37.4 bits (85), Expect = 0.024
Identities = 24/68 (35%), Positives = 38/68 (55%), Gaps = 7/68 (10%)
Query: 122 IHCKAGKGRTG--VMICAYLLHRGKFLKAQEALDFYGEV-RTRDKKGVTIPSQRRYVYYY 178
+HC AG GRTG V+I A L + + +D YG V R R ++ + + +YV+ Y
Sbjct: 440 VHCSAGVGRTGTFVVIDAML----DMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIY 495
Query: 179 SYLLKNHL 186
LL+++L
Sbjct: 496 QALLEHYL 503
Score = 32.7 bits (73), Expect = 0.60
Identities = 23/77 (29%), Positives = 42/77 (54%), Gaps = 8/77 (10%)
Query: 114 EDDNHVAAIHCKAGKGRTGVMICAY--LLHRGKFLKAQEALDFYGEVRT-RDKKGVTIPS 170
+ NH +HC AG GRTG CA +L R +KA+ LD + V++ R ++ + +
Sbjct: 722 QSGNHPITVHCSAGAGRTGT-FCALSTVLER---VKAEGILDVFQTVKSLRLQRPHMVQT 777
Query: 171 QRRYVYYYSYLLKNHLD 187
+Y + Y +++ ++D
Sbjct: 778 LEQYEFCYK-VVQEYID 793
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,788,256
Number of Sequences: 37866
Number of extensions: 785102
Number of successful extensions: 2431
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 69
Number of HSP's that attempted gapping in prelim test: 2320
Number of HSP's gapped (non-prelim): 150
length of query: 403
length of database: 18,247,518
effective HSP length: 105
effective length of query: 298
effective length of database: 14,271,588
effective search space: 4252933224
effective search space used: 4252933224
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.