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Search of human proteins with 73747799
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|73747799 vacuolar protein sorting 52 [Homo sapiens]
(723 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|73747799 vacuolar protein sorting 52 [Homo sapiens] 1401 0.0
gi|30794488 kinesin family member 27 [Homo sapiens] 41 0.003
gi|21450705 leucine rich repeat containing 45 [Homo sapiens] 40 0.006
gi|148233596 LPS-responsive vesicle trafficking, beach and ancho... 38 0.029
gi|30410716 exocyst complex component 1 isoform 2 [Homo sapiens] 37 0.049
gi|23503243 Ras association (RalGDS/AF-6) domain family (N-termi... 37 0.064
gi|4503593 epidermal growth factor receptor pathway substrate 15... 37 0.084
gi|67944634 exocyst complex component 1 isoform 1 [Homo sapiens] 36 0.11
gi|30410720 exocyst complex component 1 isoform 1 [Homo sapiens] 36 0.11
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 36 0.14
gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens] 35 0.19
gi|116488398 keratin 32 [Homo sapiens] 35 0.19
gi|31377798 rabaptin, RAB GTPase binding effector protein 1 isof... 35 0.19
gi|205277396 dynactin 1 isoform 4 [Homo sapiens] 35 0.24
gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 35 0.24
gi|13259508 dynactin 1 isoform 2 [Homo sapiens] 35 0.24
gi|13259510 dynactin 1 isoform 1 [Homo sapiens] 35 0.24
gi|194294510 kinesin family member C3 isoform 2 [Homo sapiens] 35 0.24
gi|194294508 kinesin family member C3 isoform 3 [Homo sapiens] 35 0.24
gi|94536858 kinesin family member C3 isoform 1 [Homo sapiens] 35 0.24
gi|10337581 type I hair keratin 3B [Homo sapiens] 35 0.32
gi|22027616 TNF receptor-associated factor 3 isoform 1 [Homo sap... 35 0.32
gi|22027620 TNF receptor-associated factor 3 isoform 2 [Homo sap... 35 0.32
gi|22027618 TNF receptor-associated factor 3 isoform 1 [Homo sap... 35 0.32
gi|71061468 centromere protein E [Homo sapiens] 34 0.42
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 34 0.42
gi|30089960 CDC42-binding protein kinase alpha isoform A [Homo s... 34 0.42
gi|115511012 coiled-coil domain containing 136 [Homo sapiens] 34 0.42
gi|30260188 Golgi autoantigen, golgin subfamily a, 5 [Homo sapiens] 34 0.42
gi|223671870 inhibitor of kappa light polypeptide gene enhancer ... 34 0.54
>gi|73747799 vacuolar protein sorting 52 [Homo sapiens]
Length = 723
Score = 1401 bits (3626), Expect = 0.0
Identities = 723/723 (100%), Positives = 723/723 (100%)
Query: 1 MAAAATMAAAARELVLRAGTSDMEEEEGPLAGGPGLQEPLQLGELDITSDEFILDEVDVH 60
MAAAATMAAAARELVLRAGTSDMEEEEGPLAGGPGLQEPLQLGELDITSDEFILDEVDVH
Sbjct: 1 MAAAATMAAAARELVLRAGTSDMEEEEGPLAGGPGLQEPLQLGELDITSDEFILDEVDVH 60
Query: 61 IQANLEDELVKEALKTGVDLRHYSKQVELELQQIEQKSIRDYIQESENIASLHNQITACD 120
IQANLEDELVKEALKTGVDLRHYSKQVELELQQIEQKSIRDYIQESENIASLHNQITACD
Sbjct: 61 IQANLEDELVKEALKTGVDLRHYSKQVELELQQIEQKSIRDYIQESENIASLHNQITACD 120
Query: 121 AVLERMEQMLGAFQSDLSSISSEIRTLQEQSGAMNIRLRNRQAVRGKLGELVDGLVVPSA 180
AVLERMEQMLGAFQSDLSSISSEIRTLQEQSGAMNIRLRNRQAVRGKLGELVDGLVVPSA
Sbjct: 121 AVLERMEQMLGAFQSDLSSISSEIRTLQEQSGAMNIRLRNRQAVRGKLGELVDGLVVPSA 180
Query: 181 LVTAILEAPVTEPRFLEQLQELDAKAAAVREQEARGTAACADVRGVLDRLRVKAVTKIRE 240
LVTAILEAPVTEPRFLEQLQELDAKAAAVREQEARGTAACADVRGVLDRLRVKAVTKIRE
Sbjct: 181 LVTAILEAPVTEPRFLEQLQELDAKAAAVREQEARGTAACADVRGVLDRLRVKAVTKIRE 240
Query: 241 FILQKIYSFRKPMTNYQIPQTALLKYRFFYQFLLGNERATAKEIRDEYVETLSKIYLSYY 300
FILQKIYSFRKPMTNYQIPQTALLKYRFFYQFLLGNERATAKEIRDEYVETLSKIYLSYY
Sbjct: 241 FILQKIYSFRKPMTNYQIPQTALLKYRFFYQFLLGNERATAKEIRDEYVETLSKIYLSYY 300
Query: 301 RSYLGRLMKVQYEEVAEKDDLMGVEDTAKKGFFSKPSLRSRNTIFTLGTRGSVISPTELE 360
RSYLGRLMKVQYEEVAEKDDLMGVEDTAKKGFFSKPSLRSRNTIFTLGTRGSVISPTELE
Sbjct: 301 RSYLGRLMKVQYEEVAEKDDLMGVEDTAKKGFFSKPSLRSRNTIFTLGTRGSVISPTELE 360
Query: 361 APILVPHTAQRGEQRYPFEALFRSQHYALLDNSCREYLFICEFFVVSGPAAHDLFHAVMG 420
APILVPHTAQRGEQRYPFEALFRSQHYALLDNSCREYLFICEFFVVSGPAAHDLFHAVMG
Sbjct: 361 APILVPHTAQRGEQRYPFEALFRSQHYALLDNSCREYLFICEFFVVSGPAAHDLFHAVMG 420
Query: 421 RTLSMTLKHLDSYLADCYDAIAVFLCIHIVLRFRNIAAKRDVPALDRYWEQVLALLWPRF 480
RTLSMTLKHLDSYLADCYDAIAVFLCIHIVLRFRNIAAKRDVPALDRYWEQVLALLWPRF
Sbjct: 421 RTLSMTLKHLDSYLADCYDAIAVFLCIHIVLRFRNIAAKRDVPALDRYWEQVLALLWPRF 480
Query: 481 ELILEMNVQSVRSTDPQRLGGLDTRPHYITRRYAEFSSALVSINQTIPNERTMQLLGQLQ 540
ELILEMNVQSVRSTDPQRLGGLDTRPHYITRRYAEFSSALVSINQTIPNERTMQLLGQLQ
Sbjct: 481 ELILEMNVQSVRSTDPQRLGGLDTRPHYITRRYAEFSSALVSINQTIPNERTMQLLGQLQ 540
Query: 541 VEVENFVLRVAAEFSSRKEQLVFLINNYDMMLGVLMERAADDSKEVESFQQLLNARTQEF 600
VEVENFVLRVAAEFSSRKEQLVFLINNYDMMLGVLMERAADDSKEVESFQQLLNARTQEF
Sbjct: 541 VEVENFVLRVAAEFSSRKEQLVFLINNYDMMLGVLMERAADDSKEVESFQQLLNARTQEF 600
Query: 601 IEELLSPPFGGLVAFVKEAEALIERGQAERLRGEEARVTQLIRGFGSSWKSSVESLSQDV 660
IEELLSPPFGGLVAFVKEAEALIERGQAERLRGEEARVTQLIRGFGSSWKSSVESLSQDV
Sbjct: 601 IEELLSPPFGGLVAFVKEAEALIERGQAERLRGEEARVTQLIRGFGSSWKSSVESLSQDV 660
Query: 661 MRSFTNFRNGTSIIQGALTQLIQLYHRFHRVLSQPQLRALPARAELINIHHLMVELKKHK 720
MRSFTNFRNGTSIIQGALTQLIQLYHRFHRVLSQPQLRALPARAELINIHHLMVELKKHK
Sbjct: 661 MRSFTNFRNGTSIIQGALTQLIQLYHRFHRVLSQPQLRALPARAELINIHHLMVELKKHK 720
Query: 721 PNF 723
PNF
Sbjct: 721 PNF 723
>gi|30794488 kinesin family member 27 [Homo sapiens]
Length = 1401
Score = 41.2 bits (95), Expect = 0.003
Identities = 32/138 (23%), Positives = 72/138 (52%), Gaps = 14/138 (10%)
Query: 21 SDMEEEEGPLAGGPGLQEPLQLGELDITSDEFILDEV-----DVHIQANLEDELVKEALK 75
SD+E E+ + LQE +L + + E IL E ++ I ++++L+KE +K
Sbjct: 689 SDLENEDLKI---DCLQESQELNLQKLKNSERILTEAKQKMRELTINIKMKEDLIKELIK 745
Query: 76 TGVDLRHYSKQVELELQQIE---QKSIRDYIQESENIASLHNQITACDAVLERMEQMLGA 132
TG D + SKQ L++ ++E +++ + I+ + + L N+ + A+ ++++
Sbjct: 746 TGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQELENKDLSDVAMKVKLQK---E 802
Query: 133 FQSDLSSISSEIRTLQEQ 150
F+ + + ++ LQ++
Sbjct: 803 FRKKMDAAKLRVQVLQKK 820
>gi|21450705 leucine rich repeat containing 45 [Homo sapiens]
Length = 670
Score = 40.4 bits (93), Expect = 0.006
Identities = 40/163 (24%), Positives = 77/163 (47%), Gaps = 14/163 (8%)
Query: 66 EDELVKEALKTGVD----LRHYSKQVELELQQIEQKSIRDYIQESENIASLHNQITACDA 121
E+EL+K + ++ L H ++ L L Q ++ +Q+ + +A +++
Sbjct: 484 EEELIKAKSQARLEEQQRLAHLEDKLRL-LAQARDEAQGACLQQKQVVAEAQTRVSQLGL 542
Query: 122 VLERMEQMLGAFQSDLSSISSE-------IRT-LQEQSGAMNIRLRNRQAVRGKLGELVD 173
+E + + L Q +LS E +R LQEQ+G + L ++A+R K L
Sbjct: 543 QVEGLRRRLEELQQELSLKDQERVAEVSRVRVELQEQNGRLQAELAAQEALREKAAALER 602
Query: 174 GL-VVPSALVTAILEAPVTEPRFLEQLQELDAKAAAVREQEAR 215
L V+ S A+L+ E+L+ +A+ A +R++EA+
Sbjct: 603 QLKVMASDHREALLDRESENASLREKLRLREAEIARIRDEEAQ 645
Score = 38.9 bits (89), Expect = 0.017
Identities = 38/161 (23%), Positives = 76/161 (47%), Gaps = 11/161 (6%)
Query: 84 SKQVELELQQI---EQKSIRDYIQESENIASLHNQITACDAVLERMEQMLGAFQSDLSSI 140
+K+++LE Q+ E K +RD +E L NQ+ + ++ L + +++S+
Sbjct: 341 AKELKLEQQEAAERESKLLRDLSAANEKNLLLQNQVDELERKFRCQQEQLFQTRQEMTSM 400
Query: 141 SSEI--RTLQEQSGAMNIRLRNRQAVRGKLGELVDGLVVPSALVTAILEAPVTEPRFLEQ 198
S+E+ R +Q + + R RQ++ + + +T LE +E E+
Sbjct: 401 SAELKMRAIQAEERLDMEKRRCRQSLEDSESLRIKEV----EHMTRHLEE--SEKAMQER 454
Query: 199 LQELDAKAAAVREQEARGTAACADVRGVLDRLRVKAVTKIR 239
+Q L+A ++ E+ +R AA RG + +KA ++ R
Sbjct: 455 VQRLEAARLSLEEELSRVKAAALSERGQAEEELIKAKSQAR 495
>gi|148233596 LPS-responsive vesicle trafficking, beach and anchor
containing [Homo sapiens]
Length = 2863
Score = 38.1 bits (87), Expect = 0.029
Identities = 23/92 (25%), Positives = 41/92 (44%)
Query: 97 KSIRDYIQESENIASLHNQITACDAVLERMEQMLGAFQSDLSSISSEIRTLQEQSGAMNI 156
K++ D++ S+N+ +HN I V++ M G LS+ +S L+ +
Sbjct: 1339 KTVMDFVNSSDNVIFVHNTIHLISQVMDNMVMACGGILPLLSAATSATHELENIEPTQGL 1398
Query: 157 RLRNRQAVRGKLGELVDGLVVPSALVTAILEA 188
+ +L LVD L+ S+L +EA
Sbjct: 1399 SIEASVTFLQRLISLVDVLIFASSLGFTEIEA 1430
>gi|30410716 exocyst complex component 1 isoform 2 [Homo sapiens]
Length = 879
Score = 37.4 bits (85), Expect = 0.049
Identities = 55/345 (15%), Positives = 150/345 (43%), Gaps = 37/345 (10%)
Query: 36 LQEPLQLGELDITS--DEFILDEV-DVHIQANLEDELVKEALKTGV-DLRHYSKQVELEL 91
L+E + GE + DE ++DE +++ + + E++ E + + + +++++ EL
Sbjct: 137 LEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSREL 196
Query: 92 QQIEQKSIRDYIQESENIASLHNQITACDAVLERMEQMLGAFQSDLSSISSEIRTLQEQS 151
Q ++ +I+ + + + L + ++++E L +++ L S+ ++ + E +
Sbjct: 197 QVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESN 256
Query: 152 GAMNIRLRNRQAVRGKLGELVDGLVVPSALVTAILEAPVTEPRFLEQ--------LQELD 203
+++ N + ++ LV+ + + + A+ E + R +E LQ ++
Sbjct: 257 HLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRGIEACTNAADALLQCMN 316
Query: 204 AKAA-------AVREQEARGTAACADVRGVLDRLRVKAVTKIREFILQKIYSFRKPMTNY 256
AV++Q+ R +D+R + R + + + +Q+ + + +
Sbjct: 317 VALRPGHDLLLAVKQQQQR----FSDLRELFAR---RLASHLNNVFVQQGHDQSSTLAQH 369
Query: 257 QIPQTA---------LLKYRFFYQFLLGNERATAKEIRDEYVETLSKIYLSYYRSYLGRL 307
+ T LL+Y ++L + + + Y++ LS++Y + + +
Sbjct: 370 SVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDYLSRLYEREIKDFF-EV 428
Query: 308 MKVQYEEVAEKDDLMGVEDTAKKGFFSKPSLRSRNTIFTLGTRGS 352
K++ ++ G+ ++ K S SL ++ ++ + G R S
Sbjct: 429 AKIKMTGTTKESKKFGLHGSSGKLTGSTSSL-NKLSVQSSGNRRS 472
>gi|23503243 Ras association (RalGDS/AF-6) domain family
(N-terminal) member 8 [Homo sapiens]
Length = 392
Score = 37.0 bits (84), Expect = 0.064
Identities = 33/138 (23%), Positives = 66/138 (47%), Gaps = 18/138 (13%)
Query: 38 EPLQLGELDITSDEFILDEVDVHIQANLEDELVK---EALKTGVDLRHYSK-QVELELQQ 93
E LQ E + S+E + + +NLE+E+V+ + + V++ + EL+++Q
Sbjct: 175 EKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQ 234
Query: 94 IEQKSIRDYIQESENIASLHNQITACDAVLERMEQMLGAFQSDLSSISSEIRTLQEQSGA 153
+K ++D +QE + +IT C+ L+ + +S L E LQ +
Sbjct: 235 ENEKQLKDQLQE------IRQKITECENKLKDYLAQIRTMESGL-----EAEKLQREVQE 283
Query: 154 MNIRLRNRQAVRGKLGEL 171
+ N + V+GK+G++
Sbjct: 284 AQV---NEEEVKGKIGKV 298
>gi|4503593 epidermal growth factor receptor pathway substrate 15
isoform A [Homo sapiens]
Length = 896
Score = 36.6 bits (83), Expect = 0.084
Identities = 37/162 (22%), Positives = 70/162 (43%), Gaps = 11/162 (6%)
Query: 62 QANLEDELVKEALKTGVDLRHY--------SKQVELELQQIEQKSIRDYIQESENIASLH 113
Q L L+ + L G+D H S + L+ I + D+ E + +L+
Sbjct: 281 QFALAFHLISQKLIKGIDPPHVLTPEMIPPSDRASLQKNIIGSSPVADFSAIKE-LDTLN 339
Query: 114 NQITACDAVLERMEQMLGAFQSDLSSISSEIRTLQEQSGAMNIRLRNRQAVRGKLGELVD 173
N+I +EQ L + + +SE++ LQ++ N L+ QA + ++ EL+D
Sbjct: 340 NEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLD 399
Query: 174 GLVVPSALVTAILEAPVTEPRFLEQLQELDAKAAAVREQEAR 215
L A + L+ + E+ Q + + A + QE++
Sbjct: 400 ELDEQKAQLEEQLKE--VRKKCAEEAQLISSLKAELTSQESQ 439
>gi|67944634 exocyst complex component 1 isoform 1 [Homo sapiens]
Length = 894
Score = 36.2 bits (82), Expect = 0.11
Identities = 46/289 (15%), Positives = 126/289 (43%), Gaps = 35/289 (12%)
Query: 36 LQEPLQLGELDITS--DEFILDEV-DVHIQANLEDELVKEALKTGV-DLRHYSKQVELEL 91
L+E + GE + DE ++DE +++ + + E++ E + + + +++++ EL
Sbjct: 137 LEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSREL 196
Query: 92 QQIEQKSIRDYIQESENIASLHNQITACDAVLERMEQMLGAFQSDLSSISSEIRTLQEQS 151
Q ++ +I+ + + + L + ++++E L +++ L S+ ++ + E +
Sbjct: 197 QVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESN 256
Query: 152 GAMNIRLRNRQAVRGKLGELVDGLVVPSALVTAILEAPVTEPRFLEQ--------LQELD 203
+++ N + ++ LV+ + + + A+ E + R +E LQ ++
Sbjct: 257 HLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRGIEACTNAADALLQCMN 316
Query: 204 AKAA-------AVREQEARGTAACADVRGVLDRLRVKAVTKIREFILQKIYSFRKPMTNY 256
AV++Q+ R +D+R + R + + + +Q+ + + +
Sbjct: 317 VALRPGHDLLLAVKQQQQR----FSDLRELFAR---RLASHLNNVFVQQGHDQSSTLAQH 369
Query: 257 QIPQTA---------LLKYRFFYQFLLGNERATAKEIRDEYVETLSKIY 296
+ T LL+Y ++L + + + Y++ LS++Y
Sbjct: 370 SVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDYLSRLY 418
>gi|30410720 exocyst complex component 1 isoform 1 [Homo sapiens]
Length = 894
Score = 36.2 bits (82), Expect = 0.11
Identities = 46/289 (15%), Positives = 126/289 (43%), Gaps = 35/289 (12%)
Query: 36 LQEPLQLGELDITS--DEFILDEV-DVHIQANLEDELVKEALKTGV-DLRHYSKQVELEL 91
L+E + GE + DE ++DE +++ + + E++ E + + + +++++ EL
Sbjct: 137 LEESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSREL 196
Query: 92 QQIEQKSIRDYIQESENIASLHNQITACDAVLERMEQMLGAFQSDLSSISSEIRTLQEQS 151
Q ++ +I+ + + + L + ++++E L +++ L S+ ++ + E +
Sbjct: 197 QVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESN 256
Query: 152 GAMNIRLRNRQAVRGKLGELVDGLVVPSALVTAILEAPVTEPRFLEQ--------LQELD 203
+++ N + ++ LV+ + + + A+ E + R +E LQ ++
Sbjct: 257 HLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLASSRGIEACTNAADALLQCMN 316
Query: 204 AKAA-------AVREQEARGTAACADVRGVLDRLRVKAVTKIREFILQKIYSFRKPMTNY 256
AV++Q+ R +D+R + R + + + +Q+ + + +
Sbjct: 317 VALRPGHDLLLAVKQQQQR----FSDLRELFAR---RLASHLNNVFVQQGHDQSSTLAQH 369
Query: 257 QIPQTA---------LLKYRFFYQFLLGNERATAKEIRDEYVETLSKIY 296
+ T LL+Y ++L + + + Y++ LS++Y
Sbjct: 370 SVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDYLSRLY 418
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin
(with transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 35.8 bits (81), Expect = 0.14
Identities = 40/148 (27%), Positives = 65/148 (43%), Gaps = 22/148 (14%)
Query: 70 VKEALKTGVDLRHYSKQVELELQQIEQKSIRDYIQE-------SENIASLHNQITACDAV 122
VKE L +LR KQ+E+ L + E++ DY + +E I SL + + D
Sbjct: 753 VKE-LSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVK 811
Query: 123 LERMEQMLGAFQSDLSSISSEIRTLQEQ---------SGAMNIRLRNRQAVRGKLGELVD 173
+E ++ L Q S S+ IR+LQ Q GA +R + K+ EL
Sbjct: 812 IEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVR-----HISSKVEELSQ 866
Query: 174 GLVVPSALVTAILEAPVTEPRFLEQLQE 201
L +T + + + + R +E LQ+
Sbjct: 867 ALSQKELEITKMDQLLLEKKRDVETLQQ 894
Score = 32.0 bits (71), Expect = 2.1
Identities = 41/178 (23%), Positives = 71/178 (39%), Gaps = 30/178 (16%)
Query: 99 IRDYIQE----SENIASLHNQITACDAVLERMEQMLGAFQSDLSSISSEIRTLQEQSGAM 154
I +Y+Q+ E IA L + + +E S +S+ E++ LQE+ M
Sbjct: 1835 INNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKM 1894
Query: 155 NIRLRNRQAVRGKLGELVDGLVVPSALVTAILEAPVTEPRFLEQLQEL---------DAK 205
N+ + Q ++ +L + TA E E R + QL EL D
Sbjct: 1895 NLLNQQIQEELSRVTKLKE---------TAEEEKDDLEERLMNQLAELNGSIGNYCQDVT 1945
Query: 206 AAAVR----EQEARGTAACA----DVRGVLDRLRVKAVTKIREFILQKIYSFRKPMTN 255
A ++ E E + C + + L + + K ++IR+ L+KI +K N
Sbjct: 1946 DAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGN 2003
Score = 32.0 bits (71), Expect = 2.1
Identities = 33/155 (21%), Positives = 64/155 (41%), Gaps = 20/155 (12%)
Query: 3 AAATMAAAARELVLRAGTSDMEEEEGPLAGGPGLQEPLQLGELDITSDEFILDEVDVHIQ 62
+A A E V D+E + LA E + + ++ S + +LD+
Sbjct: 2036 SALERTVKALEFVQTESQKDLEITKENLAQAV---EHRKKAQAELASFKVLLDDTQSEAA 2092
Query: 63 ANLEDELV--------KEALKTGVDLRHYSKQVELELQQIEQKSIRDYIQESENIASLHN 114
L D L KE++K+ ++ + +E L+Q E+K +++ E + +L
Sbjct: 2093 RVLADNLKLKKELQSNKESVKS--QMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRR 2150
Query: 115 QITACDAVLERMEQMLGAFQSDLSSISSEIRTLQE 149
+ +E+ +G Q L+ E++ LQE
Sbjct: 2151 EKV-------HLEETIGEIQVTLNKKDKEVQQLQE 2178
>gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]
Length = 4471
Score = 35.4 bits (80), Expect = 0.19
Identities = 40/200 (20%), Positives = 90/200 (45%), Gaps = 19/200 (9%)
Query: 61 IQANLEDELVKEALKTGVDLRHYSKQVELELQQIEQKSIRDYIQESENIASLHNQITACD 120
I A + +VK + + HYS+Q +L++ + ++Y+ + L ++ T C+
Sbjct: 2981 IPAENIENVVKHVVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCN 3040
Query: 121 -AVLERMEQMLGAFQSDLSSISSEIRTLQEQSGAMNIRLRNRQAVRGKLGELVDGLVVPS 179
A +R++ L +++ Q +N +L ++ V + + L+
Sbjct: 3041 IAQCKRLDGGL-----------DKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEI 3089
Query: 180 ALVTAILEAPVTEPRFL--EQLQELDAKAAAVREQEARGTAACADVRGVLDRLRVKAVTK 237
A+ TA+ E E + L E+ E++ + + ++A A+V +L+ +++ + K
Sbjct: 3090 AVNTAVAE----EKKKLAEEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLE-LQK 3144
Query: 238 IREFILQKIYSFRKPMTNYQ 257
+ + + +I SF KP Q
Sbjct: 3145 LDKSDVTEIRSFAKPPKQVQ 3164
>gi|116488398 keratin 32 [Homo sapiens]
Length = 448
Score = 35.4 bits (80), Expect = 0.19
Identities = 28/129 (21%), Positives = 62/129 (48%), Gaps = 4/129 (3%)
Query: 471 QVLALLWPRFELILEMNVQSVRSTDPQRLGGLDTRPHYITRRYAEFSSALVSINQTIPN- 529
+VL + ++E ++E N + V ++ L+ + + + + S ++ + +T+
Sbjct: 263 RVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNYQSDIIDLRRTVNTL 322
Query: 530 ERTMQLLGQLQVEVENFVLRVAAEFSSRKEQLVFLINNYDMMLGVLMERAADDSKEVESF 589
E +Q L+ +EN + A +SS+ Q+ +I N + L E AD ++ + +
Sbjct: 323 EIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLA---EIRADLERQNQEY 379
Query: 590 QQLLNARTQ 598
Q LL+ R +
Sbjct: 380 QVLLDVRAR 388
>gi|31377798 rabaptin, RAB GTPase binding effector protein 1 isoform
1 [Homo sapiens]
Length = 862
Score = 35.4 bits (80), Expect = 0.19
Identities = 46/226 (20%), Positives = 100/226 (44%), Gaps = 17/226 (7%)
Query: 23 MEEEEGPLAGGPGLQEPLQLGELDITSD------EFILDEVDVHIQANLEDELVKEALKT 76
++++ L G L LQ E I D E +L + I + V+E LK
Sbjct: 645 LQKDNDSLQGKHSLHVSLQQAEDFILPDTTEALRELVLKYREDIINVRTAADHVEEKLKA 704
Query: 77 GVDLRHYSKQVELELQQIEQKSIRDYIQ-ESENIASLHNQITACDAVLERMEQMLGAFQS 135
++ +Q++ E Q ++++ + +Q E EN I++ A LER++ G +S
Sbjct: 705 --EILFLKEQIQAE--QCLKENLEETLQLEIENCKEEIASISSLKAELERIKVEKGQLES 760
Query: 136 DLSSISSEIRTLQEQSGAMNIRLRNRQAVRGKLGELV-DGLVVPSALVTAILEAPVTEPR 194
L S ++ +LQE ++ +L+ A + + +L+ + L T + + +
Sbjct: 761 TLREKSQQLESLQEIKISLEEQLKKETAAKATVEQLMFEEKNKAQRLQTELDVSEQVQRD 820
Query: 195 FLEQLQELDAKAAAVREQEARGTAACADVRGVLDRLRVKAVTKIRE 240
F++ Q L + +R+ + + +R +L+ ++ + ++ E
Sbjct: 821 FVKLSQTLQVQLERIRQAD-----SLERIRAILNDTKLTDINQLPE 861
>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
Length = 1139
Score = 35.0 bits (79), Expect = 0.24
Identities = 49/224 (21%), Positives = 90/224 (40%), Gaps = 21/224 (9%)
Query: 21 SDMEEEEGPLAGGPGLQEPLQLGELDITSDEFILDEVDVH-IQANLEDELVKEALKTGVD 79
S +EEEG A L+E L+ L D+ L E++ H IQ E + + D
Sbjct: 78 SPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQAD 137
Query: 80 LRHYSKQVELELQQIEQKSIRDYIQESENIASLHNQIT-----------ACDAVLERMEQ 128
L+ K+ E ++ + R Y++E + A T + +E +++
Sbjct: 138 LQRRLKEARKEAKEALEAKER-YMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKE 196
Query: 129 MLGAFQSDLSSISSEIRTLQEQSGAMNIRLRNRQAVRGKLGELVDGLVVPSALVTAILEA 188
+ +DL + +EI A + +L+ + + L D LV L ++ +
Sbjct: 197 RVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNAR---LKDALVRMRDLSSSEKQE 253
Query: 189 PVTEPRFLEQL-QELDAKAAAVREQEARGTAACADVRGVLDRLR 231
V + +E+ QEL+ VR+Q R + +D L+
Sbjct: 254 HVKLQKLMEKKNQELE----VVRQQRERLQEELSQAESTIDELK 293
>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
Length = 1253
Score = 35.0 bits (79), Expect = 0.24
Identities = 49/224 (21%), Positives = 90/224 (40%), Gaps = 21/224 (9%)
Query: 21 SDMEEEEGPLAGGPGLQEPLQLGELDITSDEFILDEVDVH-IQANLEDELVKEALKTGVD 79
S +EEEG A L+E L+ L D+ L E++ H IQ E + + D
Sbjct: 192 SPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQAD 251
Query: 80 LRHYSKQVELELQQIEQKSIRDYIQESENIASLHNQIT-----------ACDAVLERMEQ 128
L+ K+ E ++ + R Y++E + A T + +E +++
Sbjct: 252 LQRRLKEARKEAKEALEAKER-YMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKE 310
Query: 129 MLGAFQSDLSSISSEIRTLQEQSGAMNIRLRNRQAVRGKLGELVDGLVVPSALVTAILEA 188
+ +DL + +EI A + +L+ + + L D LV L ++ +
Sbjct: 311 RVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNAR---LKDALVRMRDLSSSEKQE 367
Query: 189 PVTEPRFLEQL-QELDAKAAAVREQEARGTAACADVRGVLDRLR 231
V + +E+ QEL+ VR+Q R + +D L+
Sbjct: 368 HVKLQKLMEKKNQELE----VVRQQRERLQEELSQAESTIDELK 407
>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
Length = 1144
Score = 35.0 bits (79), Expect = 0.24
Identities = 49/224 (21%), Positives = 90/224 (40%), Gaps = 21/224 (9%)
Query: 21 SDMEEEEGPLAGGPGLQEPLQLGELDITSDEFILDEVDVH-IQANLEDELVKEALKTGVD 79
S +EEEG A L+E L+ L D+ L E++ H IQ E + + D
Sbjct: 78 SPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQAD 137
Query: 80 LRHYSKQVELELQQIEQKSIRDYIQESENIASLHNQIT-----------ACDAVLERMEQ 128
L+ K+ E ++ + R Y++E + A T + +E +++
Sbjct: 138 LQRRLKEARKEAKEALEAKER-YMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKE 196
Query: 129 MLGAFQSDLSSISSEIRTLQEQSGAMNIRLRNRQAVRGKLGELVDGLVVPSALVTAILEA 188
+ +DL + +EI A + +L+ + + L D LV L ++ +
Sbjct: 197 RVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNAR---LKDALVRMRDLSSSEKQE 253
Query: 189 PVTEPRFLEQL-QELDAKAAAVREQEARGTAACADVRGVLDRLR 231
V + +E+ QEL+ VR+Q R + +D L+
Sbjct: 254 HVKLQKLMEKKNQELE----VVRQQRERLQEELSQAESTIDELK 293
>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
Length = 1278
Score = 35.0 bits (79), Expect = 0.24
Identities = 49/224 (21%), Positives = 90/224 (40%), Gaps = 21/224 (9%)
Query: 21 SDMEEEEGPLAGGPGLQEPLQLGELDITSDEFILDEVDVH-IQANLEDELVKEALKTGVD 79
S +EEEG A L+E L+ L D+ L E++ H IQ E + + D
Sbjct: 212 SPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQAD 271
Query: 80 LRHYSKQVELELQQIEQKSIRDYIQESENIASLHNQIT-----------ACDAVLERMEQ 128
L+ K+ E ++ + R Y++E + A T + +E +++
Sbjct: 272 LQRRLKEARKEAKEALEAKER-YMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKE 330
Query: 129 MLGAFQSDLSSISSEIRTLQEQSGAMNIRLRNRQAVRGKLGELVDGLVVPSALVTAILEA 188
+ +DL + +EI A + +L+ + + L D LV L ++ +
Sbjct: 331 RVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNAR---LKDALVRMRDLSSSEKQE 387
Query: 189 PVTEPRFLEQL-QELDAKAAAVREQEARGTAACADVRGVLDRLR 231
V + +E+ QEL+ VR+Q R + +D L+
Sbjct: 388 HVKLQKLMEKKNQELE----VVRQQRERLQEELSQAESTIDELK 427
>gi|194294510 kinesin family member C3 isoform 2 [Homo sapiens]
Length = 826
Score = 35.0 bits (79), Expect = 0.24
Identities = 52/216 (24%), Positives = 83/216 (38%), Gaps = 18/216 (8%)
Query: 28 GPLAGGPGLQEPLQLGE------LDITSDEFILDEVDVHIQANLEDELVKEALKTGVDLR 81
GP G QE QL + L++ + +L E+++ +Q D L + L+
Sbjct: 166 GPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKT-DRLAEVELRL----- 219
Query: 82 HYSKQVELELQQIEQKSIRDYIQESENIASLHNQITACDAVLERMEQMLGAFQSDLSSIS 141
K E Q E++ R E IASL Q V++ +E + LS
Sbjct: 220 ---KDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQ 276
Query: 142 SEIRTLQEQSGAMNIRLRNRQAVRGKLGELVDGLVVPSALVTAILEAPVTEPRFLEQLQE 201
+ + LQEQ L+ + +L L A+ + LE + LE++Q
Sbjct: 277 ARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELER--AHGQMLEEMQS 334
Query: 202 LDA-KAAAVREQEARGTAACADVRGVLDRLRVKAVT 236
L+ K A+ E AR V L +R +T
Sbjct: 335 LEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLT 370
>gi|194294508 kinesin family member C3 isoform 3 [Homo sapiens]
Length = 687
Score = 35.0 bits (79), Expect = 0.24
Identities = 52/216 (24%), Positives = 83/216 (38%), Gaps = 18/216 (8%)
Query: 28 GPLAGGPGLQEPLQLGE------LDITSDEFILDEVDVHIQANLEDELVKEALKTGVDLR 81
GP G QE QL + L++ + +L E+++ +Q D L + L+
Sbjct: 27 GPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKT-DRLAEVELRL----- 80
Query: 82 HYSKQVELELQQIEQKSIRDYIQESENIASLHNQITACDAVLERMEQMLGAFQSDLSSIS 141
K E Q E++ R E IASL Q V++ +E + LS
Sbjct: 81 ---KDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQ 137
Query: 142 SEIRTLQEQSGAMNIRLRNRQAVRGKLGELVDGLVVPSALVTAILEAPVTEPRFLEQLQE 201
+ + LQEQ L+ + +L L A+ + LE + LE++Q
Sbjct: 138 ARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELER--AHGQMLEEMQS 195
Query: 202 LDA-KAAAVREQEARGTAACADVRGVLDRLRVKAVT 236
L+ K A+ E AR V L +R +T
Sbjct: 196 LEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLT 231
>gi|94536858 kinesin family member C3 isoform 1 [Homo sapiens]
Length = 833
Score = 35.0 bits (79), Expect = 0.24
Identities = 52/216 (24%), Positives = 83/216 (38%), Gaps = 18/216 (8%)
Query: 28 GPLAGGPGLQEPLQLGE------LDITSDEFILDEVDVHIQANLEDELVKEALKTGVDLR 81
GP G QE QL + L++ + +L E+++ +Q D L + L+
Sbjct: 166 GPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKT-DRLAEVELRL----- 219
Query: 82 HYSKQVELELQQIEQKSIRDYIQESENIASLHNQITACDAVLERMEQMLGAFQSDLSSIS 141
K E Q E++ R E IASL Q V++ +E + LS
Sbjct: 220 ---KDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQ 276
Query: 142 SEIRTLQEQSGAMNIRLRNRQAVRGKLGELVDGLVVPSALVTAILEAPVTEPRFLEQLQE 201
+ + LQEQ L+ + +L L A+ + LE + LE++Q
Sbjct: 277 ARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELER--AHGQMLEEMQS 334
Query: 202 LDA-KAAAVREQEARGTAACADVRGVLDRLRVKAVT 236
L+ K A+ E AR V L +R +T
Sbjct: 335 LEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLT 370
>gi|10337581 type I hair keratin 3B [Homo sapiens]
Length = 404
Score = 34.7 bits (78), Expect = 0.32
Identities = 31/137 (22%), Positives = 64/137 (46%), Gaps = 6/137 (4%)
Query: 463 PALDRYWEQVLALLWPRFELILEMNVQSVRSTDPQRLGGLDTRPHYITRRYAEFSSALVS 522
PA+D QVL ++E ++E N + V + L+ + + + + + ++
Sbjct: 217 PAVDL--NQVLNETRNQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIE 274
Query: 523 INQTIPN-ERTMQLLGQLQVEVENFVLRVAAEFSSRKEQLVFLINNYDMMLGVLMERAAD 581
+ +T+ E +Q L+ +EN + A +SS+ Q+ LI N + L E +D
Sbjct: 275 LRRTVNALEIELQAQHNLRYSLENTLTESEARYSSQLSQVQSLITNVESQLA---EIRSD 331
Query: 582 DSKEVESFQQLLNARTQ 598
++ + +Q LL+ R +
Sbjct: 332 LERQNQEYQVLLDVRAR 348
>gi|22027616 TNF receptor-associated factor 3 isoform 1 [Homo
sapiens]
Length = 568
Score = 34.7 bits (78), Expect = 0.32
Identities = 19/80 (23%), Positives = 46/80 (57%), Gaps = 4/80 (5%)
Query: 80 LRHYSKQVELELQQIEQKSIRDYIQESENIASLHNQITACDAVLERMEQMLGAFQSDLSS 139
L+ +S +E ++ ++ +S+ +++++I SLHNQI + + +ER ++ML +S +
Sbjct: 263 LKEWSNSLEKKVSLLQNESV----EKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILH 318
Query: 140 ISSEIRTLQEQSGAMNIRLR 159
+ I + E+ ++ +R
Sbjct: 319 LQRVIDSQAEKLKELDKEIR 338
>gi|22027620 TNF receptor-associated factor 3 isoform 2 [Homo
sapiens]
Length = 543
Score = 34.7 bits (78), Expect = 0.32
Identities = 19/80 (23%), Positives = 46/80 (57%), Gaps = 4/80 (5%)
Query: 80 LRHYSKQVELELQQIEQKSIRDYIQESENIASLHNQITACDAVLERMEQMLGAFQSDLSS 139
L+ +S +E ++ ++ +S+ +++++I SLHNQI + + +ER ++ML +S +
Sbjct: 238 LKEWSNSLEKKVSLLQNESV----EKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILH 293
Query: 140 ISSEIRTLQEQSGAMNIRLR 159
+ I + E+ ++ +R
Sbjct: 294 LQRVIDSQAEKLKELDKEIR 313
>gi|22027618 TNF receptor-associated factor 3 isoform 1 [Homo
sapiens]
Length = 568
Score = 34.7 bits (78), Expect = 0.32
Identities = 19/80 (23%), Positives = 46/80 (57%), Gaps = 4/80 (5%)
Query: 80 LRHYSKQVELELQQIEQKSIRDYIQESENIASLHNQITACDAVLERMEQMLGAFQSDLSS 139
L+ +S +E ++ ++ +S+ +++++I SLHNQI + + +ER ++ML +S +
Sbjct: 263 LKEWSNSLEKKVSLLQNESV----EKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILH 318
Query: 140 ISSEIRTLQEQSGAMNIRLR 159
+ I + E+ ++ +R
Sbjct: 319 LQRVIDSQAEKLKELDKEIR 338
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 34.3 bits (77), Expect = 0.42
Identities = 60/279 (21%), Positives = 113/279 (40%), Gaps = 35/279 (12%)
Query: 70 VKEALKTGVDLRHYSKQVELELQQIEQKSIRDYIQESENIASLHNQITACDAVLERMEQM 129
+K K DL+ + ++ E Q+++ +I++ + + ++ L+ E+
Sbjct: 1437 MKSVAKEKDDLQRLQEVLQSESDQLKE-NIKEIVAKH---LETEEELKVAHCCLKEQEET 1492
Query: 130 LGAFQSDLSSISSEIRTLQEQSGAMNIRLRNR----------------QAVRGKLGELVD 173
+ + +LS +EI T+Q+Q A+N +L+N+ V+ K+ EL
Sbjct: 1493 INELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQ 1552
Query: 174 GLVVPSALVTAI--LEAPVTE-PRFLEQLQELDAKAAAVREQEARGTAACADVRGVLDRL 230
A +A+ +E+ + E L++ QE +E+ R A R L
Sbjct: 1553 FKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKEN 1612
Query: 231 RVKAVTKIREFILQKIYSFRKPMTNYQIPQTALLKYRFFYQFLLGNERATAKEIRDEYVE 290
+ V K++E +K Y F K MT Q + + E+ +++ E +E
Sbjct: 1613 TKEIVAKMKE-SQEKEYQFLK-MTAVNETQEKMCEIEHL------KEQFETQKLNLENIE 1664
Query: 291 TLSKIYLSYYRSYLGRLMKVQYEEVAEKDDLMGVEDTAK 329
T + L + V E+DDL VE+T K
Sbjct: 1665 TENIRLTQILHENLEEMRSV----TKERDDLRSVEETLK 1699
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 34.3 bits (77), Expect = 0.42
Identities = 35/168 (20%), Positives = 71/168 (42%), Gaps = 25/168 (14%)
Query: 79 DLRHYSKQVELELQQIEQKSIRDYIQESENIASLHNQITACDAVLERMEQMLGAFQSDLS 138
DL+ + +++EQ S + + +ASL +++T +A +++ +Q L +
Sbjct: 470 DLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAK 529
Query: 139 SISSEI-RTLQEQSGAMNIRLRNRQAVRGKLGELVDGLVVPSALVTAILEAPVTEPRFLE 197
+++ +TLQ+Q A Q +R ++ +L L +
Sbjct: 530 EKQAQLAQTLQQQEQA-------SQGLRHQVEQLSSSLKQKE-----------------Q 565
Query: 198 QLQELDAKAAAVREQEARGTAACADVRGVLDRLRVKAVTKIREFILQK 245
QL+E+ K A R+ A+ A A+ R R R A+ ++ +K
Sbjct: 566 QLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEK 613
>gi|30089960 CDC42-binding protein kinase alpha isoform A [Homo
sapiens]
Length = 1638
Score = 34.3 bits (77), Expect = 0.42
Identities = 31/112 (27%), Positives = 55/112 (49%), Gaps = 16/112 (14%)
Query: 54 LDEVDVHIQANLEDELVKEALKTGVDLRHYSKQVELELQQIEQKSIRDYIQESENIASLH 113
L++++VH +A L E K+ K HYSKQ+E EL+ ++QK I S + S+
Sbjct: 547 LNKLEVHTEA-LAAEASKDR-KLREQSEHYSKQLENELEGLKQKQ----ISYSPGVCSIE 600
Query: 114 NQ--ITACDAVLER--------MEQMLGAFQSDLSSISSEIRTLQEQSGAMN 155
+Q IT LE+ + + G +++ ++ E+ + Q A+N
Sbjct: 601 HQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKKELHDSEGQQLALN 652
>gi|115511012 coiled-coil domain containing 136 [Homo sapiens]
Length = 1154
Score = 34.3 bits (77), Expect = 0.42
Identities = 22/75 (29%), Positives = 41/75 (54%), Gaps = 6/75 (8%)
Query: 88 ELELQQIEQKSIRDYIQES-----ENIASLHNQITACDAVLERMEQMLGAFQSDLSSISS 142
EL L Q E +S+R ++S +IASL + LE ME++ G ++ +++S+ +
Sbjct: 142 ELHLAQAEIQSLRQAAEDSATEHESDIASLQEDLCRMQNELEDMERIRGDYEMEIASLRA 201
Query: 143 EIR-TLQEQSGAMNI 156
E+ E SG++ +
Sbjct: 202 EMEMKSSEPSGSLGL 216
Score = 32.7 bits (73), Expect = 1.2
Identities = 27/113 (23%), Positives = 58/113 (51%), Gaps = 6/113 (5%)
Query: 55 DEVDVHIQANLEDELVKEALKTGVDLRHYSKQVELELQQI-EQKSIRDYIQESENIASLH 113
++ + +Q LEDE + A + V + +Q++ EL+ + E+ S+ ++ +ESE + +
Sbjct: 83 EDDSLELQGLLEDERLASAQQAEVFTKQI-QQLQGELRSLREEISLLEHEKESE-LKEIE 140
Query: 114 NQITACDAVLERMEQMLGAFQSDLSSISSEIRTLQEQSGAMNIRLRNRQAVRG 166
++ A ++ + Q A + + S+I +LQE M L + + +RG
Sbjct: 141 QELHLAQAEIQSLRQ---AAEDSATEHESDIASLQEDLCRMQNELEDMERIRG 190
>gi|30260188 Golgi autoantigen, golgin subfamily a, 5 [Homo sapiens]
Length = 731
Score = 34.3 bits (77), Expect = 0.42
Identities = 38/168 (22%), Positives = 74/168 (44%), Gaps = 18/168 (10%)
Query: 66 EDELVKEALKTGVDLRHYSKQVELELQQIEQKSIRDYIQESENIASLHNQITA------- 118
E E+ +E ++ + H Q+ ELQ +E + + + E + LH+QI
Sbjct: 474 EKEMQREEIQKLMGQIH---QLRSELQDMEAQQVNEAESAREQLQDLHDQIAGQKASKQE 530
Query: 119 CDAVLERMEQMLGAFQSDL----SSISSEIRTLQEQSGAMNIRLRNRQAVRGKLGELVDG 174
+ LER++Q + DL +++ S I+ E+ + +L N+ EL +
Sbjct: 531 LETELERLKQEFHYIEEDLYRTKNTLQSRIKDRDEEIQKLRNQLTNKTLSNSSQSELENR 590
Query: 175 L-VVPSALV--TAILEAPVTEPRFLE-QLQELDAKAAAVREQEARGTA 218
L + L+ +LE+ TE L QL+ L+ + + + G++
Sbjct: 591 LHQLTETLIQKQTMLESLSTEKNSLVFQLERLEQQMNSASGSSSNGSS 638
>gi|223671870 inhibitor of kappa light polypeptide gene enhancer in
B-cells, kinase gamma isoform b [Homo sapiens]
Length = 487
Score = 33.9 bits (76), Expect = 0.54
Identities = 66/291 (22%), Positives = 118/291 (40%), Gaps = 35/291 (12%)
Query: 36 LQEPLQLGELDITSDEFILDEVD--VHIQANLEDEL------VKEALKT----GVDLRHY 83
L+E +L + S++ + + + +H QA+ +E +EA K G++
Sbjct: 123 LEENQELRDAIRQSNQILRERCEELLHFQASQREEKEFLMCKFQEARKLVERLGLEKLDL 182
Query: 84 SKQVELELQQIEQKSIRDYIQESENIASLHNQITACDAVLERMEQMLGAFQSDLSSISSE 143
+Q E L+++E R Q +E+ AS+ Q+T+ L+ + L A + ++
Sbjct: 183 KRQKEQALREVEHLK-RCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKECQALEGR 241
Query: 144 IRTLQEQSGAMNIRLRNRQAVRGKLGELVDGLVVPSALVTAIL----EAPVTEPRFLEQL 199
R EQ+ + R+A++ + VD L + V A L +A E R L QL
Sbjct: 242 ARAASEQARQLE---SEREALQQQHSVQVDQLRMQGQSVEAALRMERQAASEEKRKLAQL 298
Query: 200 --------QELD--AKAAAVREQEARGTAACADVRGVLDRLRVKAVTKIREFILQKIYSF 249
QE D K++ V + RG D++ L + V K K +
Sbjct: 299 QVAYHQLFQEYDNHIKSSVVGSERKRG-MQLEDLKQQLQQAEEALVAKQEVIDKLKEEAE 357
Query: 250 RKPMTNYQIP----QTALLKYRFFYQFLLGNERATAKEIRDEYVETLSKIY 296
+ + +P Q + K F + + A KE+ E +E L + Y
Sbjct: 358 QHKIVMETVPVLKAQADIYKADFQAERQAREKLAEKKELLQEQLEQLQREY 408
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,587,508
Number of Sequences: 37866
Number of extensions: 977442
Number of successful extensions: 3357
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 116
Number of HSP's that attempted gapping in prelim test: 3237
Number of HSP's gapped (non-prelim): 269
length of query: 723
length of database: 18,247,518
effective HSP length: 110
effective length of query: 613
effective length of database: 14,082,258
effective search space: 8632424154
effective search space used: 8632424154
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.