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Search of human proteins with 73390140
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|73390140 LIM domain kinase 2 isoform 1 [Homo sapiens]
(686 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|73390140 LIM domain kinase 2 isoform 1 [Homo sapiens] 1404 0.0
gi|8051618 LIM domain kinase 2 isoform 2b [Homo sapiens] 1169 0.0
gi|5031869 LIM domain kinase 2 isoform 2a [Homo sapiens] 1137 0.0
gi|4505001 LIM domain kinase 1 [Homo sapiens] 633 0.0
gi|66932999 testis-specific protein kinase 1 [Homo sapiens] 224 2e-58
gi|239755567 PREDICTED: similar to protein phosphatase 1 regulat... 216 4e-56
gi|20162550 protein phosphatase 1 regulatory subunit 14B [Homo s... 216 4e-56
gi|110349799 testis-specific protein kinase 2 [Homo sapiens] 202 6e-52
gi|19311006 protein phosphatase 1, regulatory (inhibitor) subuni... 137 3e-32
gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sap... 117 3e-26
gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sap... 117 3e-26
gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapi... 117 4e-26
gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens] 115 1e-25
gi|119964721 fer (fps/fes related) tyrosine kinase [Homo sapiens] 115 2e-25
gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sap... 113 5e-25
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi... 113 5e-25
gi|4758280 ephrin receptor EphA4 [Homo sapiens] 111 3e-24
gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens] 110 6e-24
gi|126362971 serine/threonine kinase 10 [Homo sapiens] 109 1e-23
gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapi... 109 1e-23
gi|4758282 ephrin receptor EphA7 [Homo sapiens] 109 1e-23
gi|21735552 mitogen-activated protein kinase kinase kinase 12 [H... 108 2e-23
gi|32967311 ephrin receptor EphA2 [Homo sapiens] 108 2e-23
gi|32528301 EPH receptor B4 precursor [Homo sapiens] 108 2e-23
gi|5454096 serine/threonine kinase 4 [Homo sapiens] 107 3e-23
gi|219842236 feline sarcoma oncogene isoform 4 [Homo sapiens] 106 6e-23
gi|219842233 feline sarcoma oncogene isoform 3 [Homo sapiens] 106 6e-23
gi|41281453 serine/threonine kinase 2 [Homo sapiens] 106 6e-23
gi|219842230 feline sarcoma oncogene isoform 2 [Homo sapiens] 106 8e-23
gi|4503687 feline sarcoma oncogene isoform 1 [Homo sapiens] 106 8e-23
>gi|73390140 LIM domain kinase 2 isoform 1 [Homo sapiens]
Length = 686
Score = 1404 bits (3633), Expect = 0.0
Identities = 686/686 (100%), Positives = 686/686 (100%)
Query: 1 MGSYLSVPAYFTSRDLFRCSECQDSLTNWYYEKDGKLYCPKDYWGKFGEFCHGCSLLMTG 60
MGSYLSVPAYFTSRDLFRCSECQDSLTNWYYEKDGKLYCPKDYWGKFGEFCHGCSLLMTG
Sbjct: 1 MGSYLSVPAYFTSRDLFRCSECQDSLTNWYYEKDGKLYCPKDYWGKFGEFCHGCSLLMTG 60
Query: 61 PFMVAGEFKYHPECFACMSCKVIIEDGDAYALVQHATLYCGKCHNEVVLAPMFERLSTES 120
PFMVAGEFKYHPECFACMSCKVIIEDGDAYALVQHATLYCGKCHNEVVLAPMFERLSTES
Sbjct: 61 PFMVAGEFKYHPECFACMSCKVIIEDGDAYALVQHATLYCGKCHNEVVLAPMFERLSTES 120
Query: 121 VQEQLPYSVTLISMPATTEGRRGFSVSVESACSNYATTVQVKEVNRMHISPNNRNAIHPG 180
VQEQLPYSVTLISMPATTEGRRGFSVSVESACSNYATTVQVKEVNRMHISPNNRNAIHPG
Sbjct: 121 VQEQLPYSVTLISMPATTEGRRGFSVSVESACSNYATTVQVKEVNRMHISPNNRNAIHPG 180
Query: 181 DRILEINGTPVRTLRVEEVEDAISQTSQTLQLLIEHDPVSQRLDQLRLEARLAPHMQNAG 240
DRILEINGTPVRTLRVEEVEDAISQTSQTLQLLIEHDPVSQRLDQLRLEARLAPHMQNAG
Sbjct: 181 DRILEINGTPVRTLRVEEVEDAISQTSQTLQLLIEHDPVSQRLDQLRLEARLAPHMQNAG 240
Query: 241 HPHALSTLDTKENLEGTLRRRSLRRSNSISKSPGPSSPKEPLLFSRDISRSESLRCSSSY 300
HPHALSTLDTKENLEGTLRRRSLRRSNSISKSPGPSSPKEPLLFSRDISRSESLRCSSSY
Sbjct: 241 HPHALSTLDTKENLEGTLRRRSLRRSNSISKSPGPSSPKEPLLFSRDISRSESLRCSSSY 300
Query: 301 SQQIFRPCDLIHGEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMR 360
SQQIFRPCDLIHGEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMR
Sbjct: 301 SQQIFRPCDLIHGEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMR 360
Query: 361 SLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSMDPFPWQQKVRFAKGIASGMAY 420
SLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSMDPFPWQQKVRFAKGIASGMAY
Sbjct: 361 SLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSMDPFPWQQKVRFAKGIASGMAY 420
Query: 421 LHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRK 480
LHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRK
Sbjct: 421 LHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRK 480
Query: 481 KRYTVVGNPYWMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVK 540
KRYTVVGNPYWMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVK
Sbjct: 481 KRYTVVGNPYWMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVK 540
Query: 541 LFWEKFVPTDCPPAFFPLAAICCRLEPESRAPPGAAGEGPGCADDEGPVRRQGKVTIKYD 600
LFWEKFVPTDCPPAFFPLAAICCRLEPESRAPPGAAGEGPGCADDEGPVRRQGKVTIKYD
Sbjct: 541 LFWEKFVPTDCPPAFFPLAAICCRLEPESRAPPGAAGEGPGCADDEGPVRRQGKVTIKYD 600
Query: 601 PKELRKHLNLEEWILEQLTRLYDCQEEEISELEIDVDELLDMESDDAWASRVKELLVDCY 660
PKELRKHLNLEEWILEQLTRLYDCQEEEISELEIDVDELLDMESDDAWASRVKELLVDCY
Sbjct: 601 PKELRKHLNLEEWILEQLTRLYDCQEEEISELEIDVDELLDMESDDAWASRVKELLVDCY 660
Query: 661 KPTEAFISGLLDKIRAMQKLSTPQKK 686
KPTEAFISGLLDKIRAMQKLSTPQKK
Sbjct: 661 KPTEAFISGLLDKIRAMQKLSTPQKK 686
>gi|8051618 LIM domain kinase 2 isoform 2b [Homo sapiens]
Length = 617
Score = 1169 bits (3024), Expect = 0.0
Identities = 570/570 (100%), Positives = 570/570 (100%)
Query: 1 MGSYLSVPAYFTSRDLFRCSECQDSLTNWYYEKDGKLYCPKDYWGKFGEFCHGCSLLMTG 60
MGSYLSVPAYFTSRDLFRCSECQDSLTNWYYEKDGKLYCPKDYWGKFGEFCHGCSLLMTG
Sbjct: 1 MGSYLSVPAYFTSRDLFRCSECQDSLTNWYYEKDGKLYCPKDYWGKFGEFCHGCSLLMTG 60
Query: 61 PFMVAGEFKYHPECFACMSCKVIIEDGDAYALVQHATLYCGKCHNEVVLAPMFERLSTES 120
PFMVAGEFKYHPECFACMSCKVIIEDGDAYALVQHATLYCGKCHNEVVLAPMFERLSTES
Sbjct: 61 PFMVAGEFKYHPECFACMSCKVIIEDGDAYALVQHATLYCGKCHNEVVLAPMFERLSTES 120
Query: 121 VQEQLPYSVTLISMPATTEGRRGFSVSVESACSNYATTVQVKEVNRMHISPNNRNAIHPG 180
VQEQLPYSVTLISMPATTEGRRGFSVSVESACSNYATTVQVKEVNRMHISPNNRNAIHPG
Sbjct: 121 VQEQLPYSVTLISMPATTEGRRGFSVSVESACSNYATTVQVKEVNRMHISPNNRNAIHPG 180
Query: 181 DRILEINGTPVRTLRVEEVEDAISQTSQTLQLLIEHDPVSQRLDQLRLEARLAPHMQNAG 240
DRILEINGTPVRTLRVEEVEDAISQTSQTLQLLIEHDPVSQRLDQLRLEARLAPHMQNAG
Sbjct: 181 DRILEINGTPVRTLRVEEVEDAISQTSQTLQLLIEHDPVSQRLDQLRLEARLAPHMQNAG 240
Query: 241 HPHALSTLDTKENLEGTLRRRSLRRSNSISKSPGPSSPKEPLLFSRDISRSESLRCSSSY 300
HPHALSTLDTKENLEGTLRRRSLRRSNSISKSPGPSSPKEPLLFSRDISRSESLRCSSSY
Sbjct: 241 HPHALSTLDTKENLEGTLRRRSLRRSNSISKSPGPSSPKEPLLFSRDISRSESLRCSSSY 300
Query: 301 SQQIFRPCDLIHGEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMR 360
SQQIFRPCDLIHGEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMR
Sbjct: 301 SQQIFRPCDLIHGEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMR 360
Query: 361 SLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSMDPFPWQQKVRFAKGIASGMAY 420
SLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSMDPFPWQQKVRFAKGIASGMAY
Sbjct: 361 SLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSMDPFPWQQKVRFAKGIASGMAY 420
Query: 421 LHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRK 480
LHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRK
Sbjct: 421 LHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRK 480
Query: 481 KRYTVVGNPYWMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVK 540
KRYTVVGNPYWMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVK
Sbjct: 481 KRYTVVGNPYWMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVK 540
Query: 541 LFWEKFVPTDCPPAFFPLAAICCRLEPESR 570
LFWEKFVPTDCPPAFFPLAAICCRLEPESR
Sbjct: 541 LFWEKFVPTDCPPAFFPLAAICCRLEPESR 570
>gi|5031869 LIM domain kinase 2 isoform 2a [Homo sapiens]
Length = 638
Score = 1137 bits (2942), Expect = 0.0
Identities = 554/554 (100%), Positives = 554/554 (100%)
Query: 17 FRCSECQDSLTNWYYEKDGKLYCPKDYWGKFGEFCHGCSLLMTGPFMVAGEFKYHPECFA 76
FRCSECQDSLTNWYYEKDGKLYCPKDYWGKFGEFCHGCSLLMTGPFMVAGEFKYHPECFA
Sbjct: 38 FRCSECQDSLTNWYYEKDGKLYCPKDYWGKFGEFCHGCSLLMTGPFMVAGEFKYHPECFA 97
Query: 77 CMSCKVIIEDGDAYALVQHATLYCGKCHNEVVLAPMFERLSTESVQEQLPYSVTLISMPA 136
CMSCKVIIEDGDAYALVQHATLYCGKCHNEVVLAPMFERLSTESVQEQLPYSVTLISMPA
Sbjct: 98 CMSCKVIIEDGDAYALVQHATLYCGKCHNEVVLAPMFERLSTESVQEQLPYSVTLISMPA 157
Query: 137 TTEGRRGFSVSVESACSNYATTVQVKEVNRMHISPNNRNAIHPGDRILEINGTPVRTLRV 196
TTEGRRGFSVSVESACSNYATTVQVKEVNRMHISPNNRNAIHPGDRILEINGTPVRTLRV
Sbjct: 158 TTEGRRGFSVSVESACSNYATTVQVKEVNRMHISPNNRNAIHPGDRILEINGTPVRTLRV 217
Query: 197 EEVEDAISQTSQTLQLLIEHDPVSQRLDQLRLEARLAPHMQNAGHPHALSTLDTKENLEG 256
EEVEDAISQTSQTLQLLIEHDPVSQRLDQLRLEARLAPHMQNAGHPHALSTLDTKENLEG
Sbjct: 218 EEVEDAISQTSQTLQLLIEHDPVSQRLDQLRLEARLAPHMQNAGHPHALSTLDTKENLEG 277
Query: 257 TLRRRSLRRSNSISKSPGPSSPKEPLLFSRDISRSESLRCSSSYSQQIFRPCDLIHGEVL 316
TLRRRSLRRSNSISKSPGPSSPKEPLLFSRDISRSESLRCSSSYSQQIFRPCDLIHGEVL
Sbjct: 278 TLRRRSLRRSNSISKSPGPSSPKEPLLFSRDISRSESLRCSSSYSQQIFRPCDLIHGEVL 337
Query: 317 GKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYK 376
GKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYK
Sbjct: 338 GKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYK 397
Query: 377 DKKLNLLTEYIEGGTLKDFLRSMDPFPWQQKVRFAKGIASGMAYLHSMCIIHRDLNSHNC 436
DKKLNLLTEYIEGGTLKDFLRSMDPFPWQQKVRFAKGIASGMAYLHSMCIIHRDLNSHNC
Sbjct: 398 DKKLNLLTEYIEGGTLKDFLRSMDPFPWQQKVRFAKGIASGMAYLHSMCIIHRDLNSHNC 457
Query: 437 LIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRKKRYTVVGNPYWMAPEM 496
LIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRKKRYTVVGNPYWMAPEM
Sbjct: 458 LIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRKKRYTVVGNPYWMAPEM 517
Query: 497 LNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKFVPTDCPPAFF 556
LNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKFVPTDCPPAFF
Sbjct: 518 LNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKFVPTDCPPAFF 577
Query: 557 PLAAICCRLEPESR 570
PLAAICCRLEPESR
Sbjct: 578 PLAAICCRLEPESR 591
>gi|4505001 LIM domain kinase 1 [Homo sapiens]
Length = 647
Score = 633 bits (1632), Expect = 0.0
Identities = 322/577 (55%), Positives = 412/577 (71%), Gaps = 25/577 (4%)
Query: 2 GSYLSVPAYFTSRDLFRCSECQDSLTNWYYEKDGKLYCPKDYWGKFGEFCHGCSLLMT-G 60
G YL D FRC +C SL++ YYEKDG+L+C KDYW ++GE CHGCS +T G
Sbjct: 35 GQYLQALNADWHADCFRCCDCSASLSHQYYEKDGQLFCKKDYWARYGESCHGCSEQITKG 94
Query: 61 PFMVAGEFKYHPECFACMSCKVIIEDGDAYALVQHATLYCGKCHNEVVLAPMFERLSTES 120
MVAGE KYHPECF C++C I DGD Y LV+H+ LYCG C+ + V+ P+ E++ +S
Sbjct: 95 LVMVAGELKYHPECFICLTCGTFIGDGDTYTLVEHSKLYCGHCYYQTVVTPVIEQILPDS 154
Query: 121 VQEQLPYSVTLISMPATTEGRRGFSVSVES-----AC-SNYATTVQVKEVNRMHISPNNR 174
LP++VTL+S+PA++ G+RG SVS++ C + ++ TV+V+ V+ +SP+ +
Sbjct: 155 PGSHLPHTVTLVSIPASSHGKRGLSVSIDPPHGPPGCGTEHSHTVRVQGVDPGCMSPDVK 214
Query: 175 NAIHPGDRILEINGTPVRTLRVEEVEDAISQTSQTLQLLIEHDPVSQRLDQLRLEARLAP 234
N+IH GDRILEINGTP+R + ++E++ I +TS+ LQL +EHDP L L P
Sbjct: 215 NSIHVGDRILEINGTPIRNVPLDEIDLLIQETSRLLQLTLEHDPHDT------LGHGLGP 268
Query: 235 HMQNAGHPHALSTLDTKENLEGTLRRRSLRRSNSISKSPGPSSPKEPLLFSRDISRSESL 294
P + R++ + RS SI +SPG S P +D+ RSESL
Sbjct: 269 ETSPLSSP----AYTPSGEAGSSARQKPVLRSCSIDRSPGAGSLGSPASQRKDLGRSESL 324
Query: 295 RCSSSYSQQIFRPCDLIHGEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLT 354
R +IFRP DLIHGEVLGKG FGQAIKVTH+ TG+VMVMKELIR DEETQ+TFL
Sbjct: 325 RVVCR-PHRIFRPSDLIHGEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLK 383
Query: 355 EVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSMDP-FPWQQKVRFAKG 413
EVKVMR L+HPNVLKFIGVLYKDK+LN +TEYI+GGTL+ ++SMD +PW Q+V FAK
Sbjct: 384 EVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKD 443
Query: 414 IASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRT 473
IASGMAYLHSM IIHRDLNSHNCL++ +K VVVADFGL+RL+V+E+ + R+
Sbjct: 444 IASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPE------GLRS 497
Query: 474 LRKNDRKKRYTVVGNPYWMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTL 533
L+K DRKKRYTVVGNPYWMAPEM+NG+SYDE VD+FSFGIVLCEIIG+V ADPD LPRT+
Sbjct: 498 LKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTM 557
Query: 534 DFGLNVKLFWEKFVPTDCPPAFFPLAAICCRLEPESR 570
DFGLNV+ F +++ P +CPP+FFP+ CC L+PE R
Sbjct: 558 DFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKR 594
>gi|66932999 testis-specific protein kinase 1 [Homo sapiens]
Length = 626
Score = 224 bits (572), Expect = 2e-58
Identities = 127/286 (44%), Positives = 165/286 (57%), Gaps = 22/286 (7%)
Query: 290 RSESLRCSSSYSQQIFRPCDLIHGEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDEETQ 349
R S R S + R D E +G GFF + KV H+ +G+VMV+K + +
Sbjct: 37 RPSSYRALRSAVSSLARVDDFHCAEKIGAGFFSEVYKVRHRQSGQVMVLK--MNKLPSNR 94
Query: 350 KTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSMDPFPWQQKVR 409
L EV++M L HPN+L+F+GV +L+ LTEY+ GGTL+ L S +P W ++
Sbjct: 95 GNTLREVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLSSPEPLSWPVRLH 154
Query: 410 FAKGIASGMAYLHSMCIIHRDLNSHNCLIKLDK---TVVVADFGLSRLIVEERKRAPMEK 466
A IA G+ YLHS + HRDL S NCL++ + T VV DFGL+ I R+ A
Sbjct: 155 LALDIARGLRYLHSKGVFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGA---- 210
Query: 467 ATTKKRTLRKNDRKKRYTVVGNPYWMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYADP 526
RK+ VVG+PYWMAPE+L G+ YDE D+F+FGIVLCE+I +V ADP
Sbjct: 211 ------------RKEPLAVVGSPYWMAPEVLRGELYDEKADVFAFGIVLCELIARVPADP 258
Query: 527 DCLPRTLDFGLNVKLFWEKFVPTDCPPAFFPLAAICCRLEPESRAP 572
D LPRT DFGL+V F V DCP F LA CC LEP +RAP
Sbjct: 259 DYLPRTEDFGLDVPAF-RTLVGDDCPLPFLLLAIHCCNLEPSTRAP 303
>gi|239755567 PREDICTED: similar to protein phosphatase 1 regulatory
subunit 14B [Homo sapiens]
Length = 147
Score = 216 bits (551), Expect = 4e-56
Identities = 107/117 (91%), Positives = 111/117 (94%)
Query: 570 RAPPGAAGEGPGCADDEGPVRRQGKVTIKYDPKELRKHLNLEEWILEQLTRLYDCQEEEI 629
++PPGAAGEGPG ADDEGPVRRQGKVT+KYD KELRK LNLEEWILEQLTRLYDCQEEEI
Sbjct: 31 QSPPGAAGEGPGGADDEGPVRRQGKVTVKYDRKELRKRLNLEEWILEQLTRLYDCQEEEI 90
Query: 630 SELEIDVDELLDMESDDAWASRVKELLVDCYKPTEAFISGLLDKIRAMQKLSTPQKK 686
ELEIDVDELLDMESDDA A+RVKELLVDCYKPTEAFISGLLDKIR MQKLSTPQKK
Sbjct: 91 PELEIDVDELLDMESDDARAARVKELLVDCYKPTEAFISGLLDKIRGMQKLSTPQKK 147
>gi|20162550 protein phosphatase 1 regulatory subunit 14B [Homo
sapiens]
Length = 147
Score = 216 bits (551), Expect = 4e-56
Identities = 107/117 (91%), Positives = 111/117 (94%)
Query: 570 RAPPGAAGEGPGCADDEGPVRRQGKVTIKYDPKELRKHLNLEEWILEQLTRLYDCQEEEI 629
++PPGAAGEGPG ADDEGPVRRQGKVT+KYD KELRK LNLEEWILEQLTRLYDCQEEEI
Sbjct: 31 QSPPGAAGEGPGGADDEGPVRRQGKVTVKYDRKELRKRLNLEEWILEQLTRLYDCQEEEI 90
Query: 630 SELEIDVDELLDMESDDAWASRVKELLVDCYKPTEAFISGLLDKIRAMQKLSTPQKK 686
ELEIDVDELLDMESDDA A+RVKELLVDCYKPTEAFISGLLDKIR MQKLSTPQKK
Sbjct: 91 PELEIDVDELLDMESDDARAARVKELLVDCYKPTEAFISGLLDKIRGMQKLSTPQKK 147
>gi|110349799 testis-specific protein kinase 2 [Homo sapiens]
Length = 571
Score = 202 bits (515), Expect = 6e-52
Identities = 109/260 (41%), Positives = 153/260 (58%), Gaps = 25/260 (9%)
Query: 314 EVLGKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGV 373
E +G GFF + KV H+A+G+VM +K + + L EV++M L HPN+L+F+GV
Sbjct: 62 EKIGSGFFSEVFKVRHRASGQVMALK--MNTLSSNRANMLKEVQLMNRLSHPNILRFMGV 119
Query: 374 LYKDKKLNLLTEYIEGGTLKDFLRSMDPFPWQQKVRFAKGIASGMAYLHSMCIIHRDLNS 433
+L+ LTEYI G L+ L S PW +V+ A IA G++YLH I HRDL S
Sbjct: 120 CVHQGQLHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTS 179
Query: 434 HNCLIKLDK---TVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRKKRYTVVGNPY 490
NCLIK D+ + VVADFGL+ I + + ++ VVG+P+
Sbjct: 180 KNCLIKRDENGYSAVVADFGLAEKIPDVSMGS------------------EKLAVVGSPF 221
Query: 491 WMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKFVPTD 550
WMAPE+L + Y+E D+FS+GI+LCEII ++ ADPD LPRT +FGL+ F + + D
Sbjct: 222 WMAPEVLRDEPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAF--QHMVGD 279
Query: 551 CPPAFFPLAAICCRLEPESR 570
CPP F L CC ++P+ R
Sbjct: 280 CPPDFLQLTFNCCNMDPKLR 299
>gi|19311006 protein phosphatase 1, regulatory (inhibitor) subunit
14C [Homo sapiens]
Length = 165
Score = 137 bits (346), Expect = 3e-32
Identities = 73/140 (52%), Positives = 93/140 (66%), Gaps = 23/140 (16%)
Query: 570 RAPPGAAGEGPGCA-------DDEGPV----------------RRQGKVTIKYDPKELRK 606
++P G AG PG + +D PV +QGKVT+KYD KELRK
Sbjct: 24 QSPRGGAGGSPGSSSGSGSSREDSAPVATAAAAGQVQQQQQRRHQQGKVTVKYDRKELRK 83
Query: 607 HLNLEEWILEQLTRLYDCQEEEISELEIDVDELLDMESDDAWASRVKELLVDCYKPTEAF 666
L LEEWI+EQL +LY C+EEE+ E+EID+D+LLD +SD+ AS+++E LVDCYKPTE F
Sbjct: 84 RLVLEEWIVEQLGQLYGCEEEEMPEVEIDIDDLLDADSDEERASKLQEALVDCYKPTEEF 143
Query: 667 ISGLLDKIRAMQKLSTPQKK 686
I LL +IR M+KLS PQKK
Sbjct: 144 IKELLSRIRGMRKLSPPQKK 163
>gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo
sapiens]
Length = 1015
Score = 117 bits (294), Expect = 3e-26
Identities = 86/280 (30%), Positives = 133/280 (47%), Gaps = 32/280 (11%)
Query: 300 YSQQIFRPCDLIHGEVLGKGFFGQAIKVTHKATGK----VMVMKELIRCDEETQKTFLTE 355
++++I C I V+G G FG+ K GK V + + E+ ++ FL E
Sbjct: 644 FAKEIEASCITIE-RVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGE 702
Query: 356 VKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSMD-PFPWQQKVRFAKGI 414
+M DHPN++ GV+ K K + ++TEY+E G+L FL+ D F Q V +GI
Sbjct: 703 ASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGI 762
Query: 415 ASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTL 474
++GM YL M +HRDL + N LI + V+DFGLSR++
Sbjct: 763 SAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVL------------------- 803
Query: 475 RKNDRKKRYTVVGNPY---WMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYAD-PDCLP 530
++D + YT G W APE + + + D++S+GIV+ E++ Y + P
Sbjct: 804 -EDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVS--YGERPYWEM 860
Query: 531 RTLDFGLNVKLFWEKFVPTDCPPAFFPLAAICCRLEPESR 570
D V+ + P DCP A + L C + E SR
Sbjct: 861 TNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSR 900
>gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo
sapiens]
Length = 1037
Score = 117 bits (294), Expect = 3e-26
Identities = 86/280 (30%), Positives = 133/280 (47%), Gaps = 32/280 (11%)
Query: 300 YSQQIFRPCDLIHGEVLGKGFFGQAIKVTHKATGK----VMVMKELIRCDEETQKTFLTE 355
++++I C I V+G G FG+ K GK V + + E+ ++ FL E
Sbjct: 666 FAKEIEASCITIE-RVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGE 724
Query: 356 VKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSMD-PFPWQQKVRFAKGI 414
+M DHPN++ GV+ K K + ++TEY+E G+L FL+ D F Q V +GI
Sbjct: 725 ASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGI 784
Query: 415 ASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTL 474
++GM YL M +HRDL + N LI + V+DFGLSR++
Sbjct: 785 SAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVL------------------- 825
Query: 475 RKNDRKKRYTVVGNPY---WMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYAD-PDCLP 530
++D + YT G W APE + + + D++S+GIV+ E++ Y + P
Sbjct: 826 -EDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVS--YGERPYWEM 882
Query: 531 RTLDFGLNVKLFWEKFVPTDCPPAFFPLAAICCRLEPESR 570
D V+ + P DCP A + L C + E SR
Sbjct: 883 TNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSR 922
>gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo
sapiens]
Length = 983
Score = 117 bits (293), Expect = 4e-26
Identities = 82/271 (30%), Positives = 131/271 (48%), Gaps = 41/271 (15%)
Query: 314 EVLGKGFFGQA----IKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLK 369
+V+G G FG+ +K+ K V + + E+ ++ FL E +M DHPN+++
Sbjct: 625 KVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIR 684
Query: 370 FIGVLYKDKKLNLLTEYIEGGTLKDFLRSMD-PFPWQQKVRFAKGIASGMAYLHSMCIIH 428
GV+ K K + ++TEY+E G+L FLR D F Q V +GIASGM YL M +H
Sbjct: 685 LEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVH 744
Query: 429 RDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRKKRYTVVGN 488
RDL + N LI + V+DFGLSR++ ++D + YT G
Sbjct: 745 RDLAARNILINSNLVCKVSDFGLSRVL--------------------EDDPEAAYTTRGG 784
Query: 489 PY---WMAPEMLNGKSYDETVDIFSFGIVLCEIIGQ------VYADPDCLPRTLDFGLNV 539
W +PE + + + D++S+GIVL E++ ++ D + + +D G +
Sbjct: 785 KIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVI-KAVDEGYRL 843
Query: 540 KLFWEKFVPTDCPPAFFPLAAICCRLEPESR 570
P DCP A + L C + + +R
Sbjct: 844 P------PPMDCPAALYQLMLDCWQKDRNNR 868
>gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]
Length = 984
Score = 115 bits (288), Expect = 1e-25
Identities = 80/265 (30%), Positives = 128/265 (48%), Gaps = 27/265 (10%)
Query: 314 EVLGKGFFGQAIKVTHKATGK--VMVMKELIRC--DEETQKTFLTEVKVMRSLDHPNVLK 369
EV+G G FG+ K K GK + V + ++ E+ ++ FL+E +M DHPN+++
Sbjct: 623 EVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIR 682
Query: 370 FIGVLYKDKKLNLLTEYIEGGTLKDFLRSMD-PFPWQQKVRFAKGIASGMAYLHSMCIIH 428
GV+ K + + ++TE++E G L FLR D F Q V +GIA+GM YL M +H
Sbjct: 683 LEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLAEMNYVH 742
Query: 429 RDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRKKRYTVVGN 488
RDL + N L+ + V+DFGLSR + ++ + K +R
Sbjct: 743 RDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVR------------- 789
Query: 489 PYWMAPEMLNGKSYDETVDIFSFGIVLCEIIG---QVYADPDCLPRTLDFGLNVKLFWEK 545
W APE + + + D++S+GIV+ E++ + Y D D ++ +
Sbjct: 790 --WTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMS----NQDVINAIEQDYRL 843
Query: 546 FVPTDCPPAFFPLAAICCRLEPESR 570
P DCP A L C + + SR
Sbjct: 844 PPPMDCPAALHQLMLDCWQKDRNSR 868
>gi|119964721 fer (fps/fes related) tyrosine kinase [Homo sapiens]
Length = 822
Score = 115 bits (287), Expect = 2e-25
Identities = 81/263 (30%), Positives = 122/263 (46%), Gaps = 21/263 (7%)
Query: 309 DLIHGEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVL 368
D+I GE+LGKG FG+ K T K V V +E + FL E K+++ DHPN++
Sbjct: 562 DVILGELLGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIV 621
Query: 369 KFIGVLYKDKKLNLLTEYIEGGTLKDFL-RSMDPFPWQQKVRFAKGIASGMAYLHSMCII 427
K IGV + + + ++ E + GG FL R D +Q V+F+ A+GM YL S I
Sbjct: 622 KLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQLVKFSLDAAAGMLYLESKNCI 681
Query: 428 HRDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRKKRYTVVG 487
HRDL + NCL+ + + ++DFG+SR + + K+ ++
Sbjct: 682 HRDLAARNCLVGENNVLKISDFGMSR----QEDGGVYSSSGLKQIPIK------------ 725
Query: 488 NPYWMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKFV 547
W APE LN Y D++SFGI+L E + P V+ +
Sbjct: 726 ---WTAPEALNYGRYSSESDVWSFGILLWETF-SLGVCPYPGMTNQQAREQVERGYRMSA 781
Query: 548 PTDCPPAFFPLAAICCRLEPESR 570
P CP + C +PE+R
Sbjct: 782 PQHCPEDISKIMMKCWDYKPENR 804
>gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo
sapiens]
Length = 986
Score = 113 bits (283), Expect = 5e-25
Identities = 79/263 (30%), Positives = 126/263 (47%), Gaps = 23/263 (8%)
Query: 314 EVLGKGFFGQAIKVTHKATGK--VMVMKELIRCD--EETQKTFLTEVKVMRSLDHPNVLK 369
+V+G G FG+ K GK + V + ++ E+ ++ FL+E +M DHPNV+
Sbjct: 625 QVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIH 684
Query: 370 FIGVLYKDKKLNLLTEYIEGGTLKDFLRSMD-PFPWQQKVRFAKGIASGMAYLHSMCIIH 428
GV+ K + ++TE++E G+L FLR D F Q V +GIA+GM YL M +H
Sbjct: 685 LEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVH 744
Query: 429 RDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRKKRYTVVGN 488
RDL + N L+ + V+DFGLSR + ++ A K +R
Sbjct: 745 RDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIR------------- 791
Query: 489 PYWMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLN-VKLFWEKFV 547
W APE + + + D++S+GIV+ E++ Y + T +N ++ +
Sbjct: 792 --WTAPEAIQYRKFTSASDVWSYGIVMWEVMS--YGERPYWDMTNQDVINAIEQDYRLPP 847
Query: 548 PTDCPPAFFPLAAICCRLEPESR 570
P DCP A L C + + R
Sbjct: 848 PMDCPSALHQLMLDCWQKDRNHR 870
>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo
sapiens]
Length = 987
Score = 113 bits (283), Expect = 5e-25
Identities = 79/263 (30%), Positives = 126/263 (47%), Gaps = 23/263 (8%)
Query: 314 EVLGKGFFGQAIKVTHKATGK--VMVMKELIRCD--EETQKTFLTEVKVMRSLDHPNVLK 369
+V+G G FG+ K GK + V + ++ E+ ++ FL+E +M DHPNV+
Sbjct: 626 QVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIH 685
Query: 370 FIGVLYKDKKLNLLTEYIEGGTLKDFLRSMD-PFPWQQKVRFAKGIASGMAYLHSMCIIH 428
GV+ K + ++TE++E G+L FLR D F Q V +GIA+GM YL M +H
Sbjct: 686 LEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVH 745
Query: 429 RDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRKKRYTVVGN 488
RDL + N L+ + V+DFGLSR + ++ A K +R
Sbjct: 746 RDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIR------------- 792
Query: 489 PYWMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLN-VKLFWEKFV 547
W APE + + + D++S+GIV+ E++ Y + T +N ++ +
Sbjct: 793 --WTAPEAIQYRKFTSASDVWSYGIVMWEVMS--YGERPYWDMTNQDVINAIEQDYRLPP 848
Query: 548 PTDCPPAFFPLAAICCRLEPESR 570
P DCP A L C + + R
Sbjct: 849 PMDCPSALHQLMLDCWQKDRNHR 871
>gi|4758280 ephrin receptor EphA4 [Homo sapiens]
Length = 986
Score = 111 bits (277), Expect = 3e-24
Identities = 83/280 (29%), Positives = 134/280 (47%), Gaps = 32/280 (11%)
Query: 300 YSQQIFRPCDLIHGEVLGKGFFGQAIKVTHKATGK--VMVMKELIRCD--EETQKTFLTE 355
++++I C I +V+G G FG+ K GK + V + ++ ++ ++ FL+E
Sbjct: 612 FAKEIDASCIKIE-KVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSE 670
Query: 356 VKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSMD-PFPWQQKVRFAKGI 414
+M DHPN++ GV+ K K + ++TEY+E G+L FLR D F Q V +GI
Sbjct: 671 ASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGI 730
Query: 415 ASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTL 474
SGM YL M +HRDL + N L+ + V+DFG+SR++
Sbjct: 731 GSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVL------------------- 771
Query: 475 RKNDRKKRYTVVGNPY---WMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYAD-PDCLP 530
++D + YT G W APE + + + D++S+GIV+ E++ Y + P
Sbjct: 772 -EDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMS--YGERPYWDM 828
Query: 531 RTLDFGLNVKLFWEKFVPTDCPPAFFPLAAICCRLEPESR 570
D ++ + P DCP A L C + E R
Sbjct: 829 SNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDR 868
>gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]
Length = 998
Score = 110 bits (274), Expect = 6e-24
Identities = 76/255 (29%), Positives = 121/255 (47%), Gaps = 23/255 (9%)
Query: 314 EVLGKGFFGQAIKVTHKATGK----VMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLK 369
EV+G G FG+ + K G+ V + + E ++ FL+E +M DHPN+++
Sbjct: 637 EVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIR 696
Query: 370 FIGVLYKDKKLNLLTEYIEGGTLKDFLRSMD-PFPWQQKVRFAKGIASGMAYLHSMCIIH 428
GV+ K + + +LTE++E L FLR D F Q V +GIA+GM YL M +H
Sbjct: 697 LEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVH 756
Query: 429 RDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRKKRYTVVGN 488
RDL + N L+ + V+DFGLSR + ++ + K +R
Sbjct: 757 RDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIR------------- 803
Query: 489 PYWMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLN-VKLFWEKFV 547
W APE + + + D++S+GIV+ E++ Y + + +N V+ +
Sbjct: 804 --WTAPEAIAYRKFTSASDVWSYGIVMWEVMS--YGERPYWDMSNQDVINAVEQDYRLPP 859
Query: 548 PTDCPPAFFPLAAIC 562
P DCP A L C
Sbjct: 860 PMDCPTALHQLMLDC 874
>gi|126362971 serine/threonine kinase 10 [Homo sapiens]
Length = 968
Score = 109 bits (272), Expect = 1e-23
Identities = 64/209 (30%), Positives = 107/209 (51%), Gaps = 26/209 (12%)
Query: 316 LGKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLY 375
LG G FG+ K +K TG + K + EE + ++ E++++ + DHP ++K +G Y
Sbjct: 42 LGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYIVEIEILATCDHPYIVKLLGAYY 101
Query: 376 KDKKLNLLTEYIEGGTLKDFLRSMDPFPWQQKVR-FAKGIASGMAYLHSMCIIHRDLNSH 434
D KL ++ E+ GG + + +D + +++ + + + +LHS IIHRDL +
Sbjct: 102 HDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHSKRIIHRDLKAG 161
Query: 435 NCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRKKRYTVVGNPYWMAP 494
N L+ L+ + +ADFG+S +TL+K D + +G PYWMAP
Sbjct: 162 NVLMTLEGDIRLADFGVS---------------AKNLKTLQKRD-----SFIGTPYWMAP 201
Query: 495 EM-----LNGKSYDETVDIFSFGIVLCEI 518
E+ + YD DI+S GI L E+
Sbjct: 202 EVVMCETMKDTPYDYKADIWSLGITLIEM 230
>gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo
sapiens]
Length = 1005
Score = 109 bits (272), Expect = 1e-23
Identities = 81/298 (27%), Positives = 137/298 (45%), Gaps = 34/298 (11%)
Query: 275 PSSPKEPLLFSRDISRSESLRCSSSYSQQIFRPCDLIHGE-VLGKGFFGQA----IKVTH 329
P EP ++ + E R S++++I IH E ++G G G+ ++V
Sbjct: 601 PGKLPEPQFYAEPHTYEEPGRAGRSFTREI--EASRIHIEKIIGSGDSGEVCYGRLRVPG 658
Query: 330 KATGKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEG 389
+ V + E ++ FL+E +M DHPN+++ GV+ + + ++TEY+E
Sbjct: 659 QRDVPVAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMEN 718
Query: 390 GTLKDFLRSMD-PFPWQQKVRFAKGIASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVAD 448
G+L FLR+ D F Q V +G+ +GM YL + +HRDL + N L+ + V+D
Sbjct: 719 GSLDTFLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSD 778
Query: 449 FGLSRLIVEERKRAPMEKATTKKRTLRKNDRKKRYTVVGNPY---WMAPEMLNGKSYDET 505
FGLSR++ ++D YT G W APE + +++
Sbjct: 779 FGLSRVL--------------------EDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSA 818
Query: 506 VDIFSFGIVLCEIIGQVYAD-PDCLPRTLDFGLNVKLFWEKFVPTDCPPAFFPLAAIC 562
D++SFG+V+ E++ Y + P D +V+ + P CP A L C
Sbjct: 819 SDVWSFGVVMWEVL--AYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDC 874
>gi|4758282 ephrin receptor EphA7 [Homo sapiens]
Length = 998
Score = 109 bits (272), Expect = 1e-23
Identities = 83/285 (29%), Positives = 129/285 (45%), Gaps = 32/285 (11%)
Query: 295 RCSSSYSQQIFRPCDLIHGEVLGKGFFGQAIKVTHKATGK----VMVMKELIRCDEETQK 350
R +++++ C I V+G G FG+ K GK V + + E+ ++
Sbjct: 619 RAVHQFAKELDASCIKIE-RVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRR 677
Query: 351 TFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSMD-PFPWQQKVR 409
FL E +M DHPNV+ GV+ + K + ++ E++E G L FLR D F Q V
Sbjct: 678 DFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVG 737
Query: 410 FAKGIASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATT 469
+GIA+GM YL M +HRDL + N L+ + V+DFGLSR+I
Sbjct: 738 MLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVI-------------- 783
Query: 470 KKRTLRKNDRKKRYTVVGNPY---WMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYAD- 525
++D + YT G W APE + + + D++S+GIV+ E++ Y +
Sbjct: 784 ------EDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMS--YGER 835
Query: 526 PDCLPRTLDFGLNVKLFWEKFVPTDCPPAFFPLAAICCRLEPESR 570
P D ++ + P DCP L C + E R
Sbjct: 836 PYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAER 880
>gi|21735552 mitogen-activated protein kinase kinase kinase 12 [Homo
sapiens]
Length = 859
Score = 108 bits (270), Expect = 2e-23
Identities = 74/219 (33%), Positives = 106/219 (48%), Gaps = 26/219 (11%)
Query: 354 TEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSMDPFPWQQKVRFAKG 413
T++K +R L HPN++ F GV + +L E+ G L + LR+ P V ++ G
Sbjct: 160 TDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDWSMG 219
Query: 414 IASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRT 473
IA GM YLH IIHRDL S N LI D V ++DFG S+ +
Sbjct: 220 IAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKEL------------------ 261
Query: 474 LRKNDRKKRYTVVGNPYWMAPEMLNGKSYDETVDIFSFGIVLCEII-GQV-YADPDCLPR 531
+D+ + + G WMAPE++ + E VDI+SFG+VL E++ G++ Y D D
Sbjct: 262 ---SDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAI 318
Query: 532 TLDFGLNVKLFWEKFVPTDCPPAFFPLAAICCRLEPESR 570
G N VP+ CP F L C +P +R
Sbjct: 319 IWGVGSN---SLHLPVPSSCPDGFKILLRQCWNSKPRNR 354
>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
Length = 976
Score = 108 bits (270), Expect = 2e-23
Identities = 85/280 (30%), Positives = 132/280 (47%), Gaps = 44/280 (15%)
Query: 307 PCDLIHGEVLGKGFFGQAIKVTHK-ATGKVMV---MKELIRCDEETQKT-FLTEVKVMRS 361
P + +V+G G FG+ K K ++GK V +K L E Q+ FL E +M
Sbjct: 610 PSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQ 669
Query: 362 LDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSMD-PFPWQQKVRFAKGIASGMAY 420
H N+++ GV+ K K + ++TEY+E G L FLR D F Q V +GIA+GM Y
Sbjct: 670 FSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVLQLVGMLRGIAAGMKY 729
Query: 421 LHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRK 480
L +M +HRDL + N L+ + V+DFGLSR++ ++D +
Sbjct: 730 LANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVL--------------------EDDPE 769
Query: 481 KRYTVVGNPY---WMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPDC-------LP 530
YT G W APE ++ + + D++SFGIV+ E++ Y + +
Sbjct: 770 ATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVM--TYGERPYWELSNHEVM 827
Query: 531 RTLDFGLNVKLFWEKFVPTDCPPAFFPLAAICCRLEPESR 570
+ ++ G + P DCP A + L C + E R
Sbjct: 828 KAINDGFRLP------TPMDCPSAIYQLMMQCWQQERARR 861
>gi|32528301 EPH receptor B4 precursor [Homo sapiens]
Length = 987
Score = 108 bits (270), Expect = 2e-23
Identities = 79/265 (29%), Positives = 121/265 (45%), Gaps = 27/265 (10%)
Query: 314 EVLGKGFFGQAIKVTHKATGK----VMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLK 369
EV+G G FG+ + KA GK V + E ++ FL+E +M +HPN+++
Sbjct: 619 EVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIR 678
Query: 370 FIGVLYKDKKLNLLTEYIEGGTLKDFLRSMD-PFPWQQKVRFAKGIASGMAYLHSMCIIH 428
GV+ + +LTE++E G L FLR D F Q V +GIASGM YL M +H
Sbjct: 679 LEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVH 738
Query: 429 RDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRKKRYTVVGN 488
RDL + N L+ + V+DFGLSR + E + K +R
Sbjct: 739 RDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIR------------- 785
Query: 489 PYWMAPEMLNGKSYDETVDIFSFGIVLCEIIG---QVYADPDCLPRTLDFGLNVKLFWEK 545
W APE + + + D +S+GIV+ E++ + Y D D ++ +
Sbjct: 786 --WTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMS----NQDVINAIEQDYRL 839
Query: 546 FVPTDCPPAFFPLAAICCRLEPESR 570
P DCP + L C + + +R
Sbjct: 840 PPPPDCPTSLHQLMLDCWQKDRNAR 864
>gi|5454096 serine/threonine kinase 4 [Homo sapiens]
Length = 487
Score = 107 bits (268), Expect = 3e-23
Identities = 90/357 (25%), Positives = 150/357 (42%), Gaps = 53/357 (14%)
Query: 314 EVLGKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGV 373
E LG+G +G K HK TG+++ +K+ + + + Q+ + E+ +M+ D P+V+K+ G
Sbjct: 34 EKLGEGSYGSVYKAIHKETGQIVAIKQ-VPVESDLQE-IIKEISIMQQCDSPHVVKYYGS 91
Query: 374 LYKDKKLNLLTEYIEGGTLKDFLRSMDPFPWQQKVR-FAKGIASGMAYLHSMCIIHRDLN 432
+K+ L ++ EY G++ D +R + + ++ + G+ YLH M IHRD+
Sbjct: 92 YFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIK 151
Query: 433 SHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRKKRYTVVGNPYWM 492
+ N L+ + +ADFG++ + + KR TV+G P+WM
Sbjct: 152 AGNILLNTEGHAKLADFGVAGQLTDTMA--------------------KRNTVIGTPFWM 191
Query: 493 APEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKFVPTDCP 552
APE++ Y+ DI+S GI E+ D P F +PT+ P
Sbjct: 192 APEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIF----------MIPTNPP 241
Query: 553 PA----------FFPLAAICCRLEPESRAPPGAAGEGPGCADDEGPVRRQGKVTIKYDPK 602
P F C PE RA + P +G + + D K
Sbjct: 242 PTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFVRSAKGVSILRDLINEAMDVK 301
Query: 603 ELRKHLNLEEWILEQLTRLYDCQEEEISEL-EIDVDELLDMESDDAWASRVKELLVD 658
R+ E R D +EE SE E+D ++ D+ RV + D
Sbjct: 302 LKRQ---------ESQQREVDQDDEENSEEDEMDSGTMVRAVGDEMGTVRVASTMTD 349
>gi|219842236 feline sarcoma oncogene isoform 4 [Homo sapiens]
Length = 694
Score = 106 bits (265), Expect = 6e-23
Identities = 106/427 (24%), Positives = 175/427 (40%), Gaps = 60/427 (14%)
Query: 172 NNRNAIHPGDRILEINGTPVRTLRVEEVEDAISQTS------QTLQLLIEH-----DPVS 220
N HP +R+ + V ++ ++ A+ + + LQ +EH P
Sbjct: 282 NEEENTHPRERVQLLGKRQVLQEALQGLQVALCSQAKLQAQQELLQTKLEHLGPGEPPPV 341
Query: 221 QRLDQLRLEARLAPHMQNAGHPHALSTLDTKENLEGTLRRRSLRRSNSISKSPGPSSPKE 280
L R + + G L L K ++ G R + +++ + G P
Sbjct: 342 LLLQDDRHSTSSSEQEREGGRTPTLEIL--KSHISGIFRPKF----SNLYRLEGEGFPSI 395
Query: 281 PLLFSRDISRSESLRCSSSY--------SQQIFRPCDLIHGEVLGKGFFGQAIKVTHKAT 332
PLL +S + L S + + DL+ GE +G+G FG+ +A
Sbjct: 396 PLLIDHLLSTQQPLTKKSGVVLHRAVPKDKWVLNHEDLVLGEQIGRGNFGEVFSGRLRAD 455
Query: 333 GKVMVMKELIRCDE----ETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIE 388
++ +K C E + + FL E ++++ HPN+++ IGV + + + ++ E ++
Sbjct: 456 NTLVAVKS---CRETLPPDLKAKFLQEARILKQYSHPNIVRLIGVCTQKQPIYIVMELVQ 512
Query: 389 GGTLKDFLRSMDP-FPWQQKVRFAKGIASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVA 447
GG FLR+ + ++ A+GM YL S C IHRDL + NCL+ + ++
Sbjct: 513 GGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKIS 572
Query: 448 DFGLSRLIVEERKRAPMEKATTKKRTLRKNDRKKRYTVVGNPYWMAPEMLNGKSYDETVD 507
DFG+SR EE ++ ++ W APE LN Y D
Sbjct: 573 DFGMSR---EEADGVYAASGGLRQVPVK---------------WTAPEALNYGRYSSESD 614
Query: 508 IFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKF----VPTDCPPAFFPLAAICC 563
++SFGI+L E + A P P + + F EK P CP A F L C
Sbjct: 615 VWSFGILLWETF-SLGASP--YPNLSN--QQTREFVEKGGRLPCPELCPDAVFRLMEQCW 669
Query: 564 RLEPESR 570
EP R
Sbjct: 670 AYEPGQR 676
>gi|219842233 feline sarcoma oncogene isoform 3 [Homo sapiens]
Length = 752
Score = 106 bits (265), Expect = 6e-23
Identities = 106/427 (24%), Positives = 175/427 (40%), Gaps = 60/427 (14%)
Query: 172 NNRNAIHPGDRILEINGTPVRTLRVEEVEDAISQTS------QTLQLLIEH-----DPVS 220
N HP +R+ + V ++ ++ A+ + + LQ +EH P
Sbjct: 340 NEEENTHPRERVQLLGKRQVLQEALQGLQVALCSQAKLQAQQELLQTKLEHLGPGEPPPV 399
Query: 221 QRLDQLRLEARLAPHMQNAGHPHALSTLDTKENLEGTLRRRSLRRSNSISKSPGPSSPKE 280
L R + + G L L K ++ G R + +++ + G P
Sbjct: 400 LLLQDDRHSTSSSEQEREGGRTPTLEIL--KSHISGIFRPKF----SNLYRLEGEGFPSI 453
Query: 281 PLLFSRDISRSESLRCSSSY--------SQQIFRPCDLIHGEVLGKGFFGQAIKVTHKAT 332
PLL +S + L S + + DL+ GE +G+G FG+ +A
Sbjct: 454 PLLIDHLLSTQQPLTKKSGVVLHRAVPKDKWVLNHEDLVLGEQIGRGNFGEVFSGRLRAD 513
Query: 333 GKVMVMKELIRCDE----ETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIE 388
++ +K C E + + FL E ++++ HPN+++ IGV + + + ++ E ++
Sbjct: 514 NTLVAVKS---CRETLPPDLKAKFLQEARILKQYSHPNIVRLIGVCTQKQPIYIVMELVQ 570
Query: 389 GGTLKDFLRSMDP-FPWQQKVRFAKGIASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVA 447
GG FLR+ + ++ A+GM YL S C IHRDL + NCL+ + ++
Sbjct: 571 GGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKIS 630
Query: 448 DFGLSRLIVEERKRAPMEKATTKKRTLRKNDRKKRYTVVGNPYWMAPEMLNGKSYDETVD 507
DFG+SR EE ++ ++ W APE LN Y D
Sbjct: 631 DFGMSR---EEADGVYAASGGLRQVPVK---------------WTAPEALNYGRYSSESD 672
Query: 508 IFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKF----VPTDCPPAFFPLAAICC 563
++SFGI+L E + A P P + + F EK P CP A F L C
Sbjct: 673 VWSFGILLWETF-SLGASP--YPNLSN--QQTREFVEKGGRLPCPELCPDAVFRLMEQCW 727
Query: 564 RLEPESR 570
EP R
Sbjct: 728 AYEPGQR 734
>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
Length = 1235
Score = 106 bits (265), Expect = 6e-23
Identities = 64/209 (30%), Positives = 100/209 (47%), Gaps = 26/209 (12%)
Query: 316 LGKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLY 375
LG G FG+ K +K T + K + EE + ++ E+ ++ S DHPN++K + Y
Sbjct: 40 LGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFY 99
Query: 376 KDKKLNLLTEYIEGGTLKDFLRSMD-PFPWQQKVRFAKGIASGMAYLHSMCIIHRDLNSH 434
+ L +L E+ GG + + ++ P Q K + YLH IIHRDL +
Sbjct: 100 YENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNKIIHRDLKAG 159
Query: 435 NCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRKKRYTVVGNPYWMAP 494
N L LD + +ADFG+S RT+++ D + +G PYWMAP
Sbjct: 160 NILFTLDGDIKLADFGVS---------------AKNTRTIQRRD-----SFIGTPYWMAP 199
Query: 495 EML-----NGKSYDETVDIFSFGIVLCEI 518
E++ + YD D++S GI L E+
Sbjct: 200 EVVMCETSKDRPYDYKADVWSLGITLIEM 228
>gi|219842230 feline sarcoma oncogene isoform 2 [Homo sapiens]
Length = 764
Score = 106 bits (264), Expect = 8e-23
Identities = 89/333 (26%), Positives = 145/333 (43%), Gaps = 43/333 (12%)
Query: 255 EGTLRRRSLRRSNSISKSPGPSSPKEPLLFSRDISRSESLRCSSSY--------SQQIFR 306
+G R ++ +++ + G P PLL +S + L S + +
Sbjct: 440 DGLPRHFIIQSLDNLYRLEGEGFPSIPLLIDHLLSTQQPLTKKSGVVLHRAVPKDKWVLN 499
Query: 307 PCDLIHGEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDE----ETQKTFLTEVKVMRSL 362
DL+ GE +G+G FG+ +A ++ +K C E + + FL E ++++
Sbjct: 500 HEDLVLGEQIGRGNFGEVFSGRLRADNTLVAVKS---CRETLPPDLKAKFLQEARILKQY 556
Query: 363 DHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSMDP-FPWQQKVRFAKGIASGMAYL 421
HPN+++ IGV + + + ++ E ++GG FLR+ + ++ A+GM YL
Sbjct: 557 SHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYL 616
Query: 422 HSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRKK 481
S C IHRDL + NCL+ + ++DFG+SR EE ++ ++
Sbjct: 617 ESKCCIHRDLAARNCLVTEKNVLKISDFGMSR---EEADGVYAASGGLRQVPVK------ 667
Query: 482 RYTVVGNPYWMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKL 541
W APE LN Y D++SFGI+L E + A P P + +
Sbjct: 668 ---------WTAPEALNYGRYSSESDVWSFGILLWETF-SLGASP--YPNLSN--QQTRE 713
Query: 542 FWEKF----VPTDCPPAFFPLAAICCRLEPESR 570
F EK P CP A F L C EP R
Sbjct: 714 FVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQR 746
>gi|4503687 feline sarcoma oncogene isoform 1 [Homo sapiens]
Length = 822
Score = 106 bits (264), Expect = 8e-23
Identities = 89/333 (26%), Positives = 145/333 (43%), Gaps = 43/333 (12%)
Query: 255 EGTLRRRSLRRSNSISKSPGPSSPKEPLLFSRDISRSESLRCSSSY--------SQQIFR 306
+G R ++ +++ + G P PLL +S + L S + +
Sbjct: 498 DGLPRHFIIQSLDNLYRLEGEGFPSIPLLIDHLLSTQQPLTKKSGVVLHRAVPKDKWVLN 557
Query: 307 PCDLIHGEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDE----ETQKTFLTEVKVMRSL 362
DL+ GE +G+G FG+ +A ++ +K C E + + FL E ++++
Sbjct: 558 HEDLVLGEQIGRGNFGEVFSGRLRADNTLVAVKS---CRETLPPDLKAKFLQEARILKQY 614
Query: 363 DHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSMDP-FPWQQKVRFAKGIASGMAYL 421
HPN+++ IGV + + + ++ E ++GG FLR+ + ++ A+GM YL
Sbjct: 615 SHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYL 674
Query: 422 HSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRKK 481
S C IHRDL + NCL+ + ++DFG+SR EE ++ ++
Sbjct: 675 ESKCCIHRDLAARNCLVTEKNVLKISDFGMSR---EEADGVYAASGGLRQVPVK------ 725
Query: 482 RYTVVGNPYWMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKL 541
W APE LN Y D++SFGI+L E + A P P + +
Sbjct: 726 ---------WTAPEALNYGRYSSESDVWSFGILLWETF-SLGASP--YPNLSN--QQTRE 771
Query: 542 FWEKF----VPTDCPPAFFPLAAICCRLEPESR 570
F EK P CP A F L C EP R
Sbjct: 772 FVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQR 804
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,775,249
Number of Sequences: 37866
Number of extensions: 1333718
Number of successful extensions: 7179
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 769
Number of HSP's successfully gapped in prelim test: 170
Number of HSP's that attempted gapping in prelim test: 4574
Number of HSP's gapped (non-prelim): 1459
length of query: 686
length of database: 18,247,518
effective HSP length: 109
effective length of query: 577
effective length of database: 14,120,124
effective search space: 8147311548
effective search space used: 8147311548
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.