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Search of human proteins with 72534750
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
(727 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 1486 0.0
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 1442 0.0
gi|38505213 YTH domain containing 2 [Homo sapiens] 130 3e-30
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 91 3e-18
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 89 1e-17
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 89 1e-17
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 89 1e-17
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 89 1e-17
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 89 1e-17
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 89 1e-17
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 87 5e-17
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 87 5e-17
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 85 2e-16
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 84 5e-16
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 83 8e-16
gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Hom... 79 1e-14
gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Hom... 79 1e-14
gi|17975763 myelin transcription factor 1 [Homo sapiens] 78 3e-14
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 78 3e-14
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 78 3e-14
gi|4504487 histidine rich calcium binding protein precursor [Hom... 78 3e-14
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 77 6e-14
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 74 4e-13
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 74 4e-13
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 74 4e-13
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 74 5e-13
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 74 5e-13
gi|31377750 YTH domain family, member 1 [Homo sapiens] 74 6e-13
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 73 1e-12
gi|148746195 trichohyalin [Homo sapiens] 73 1e-12
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 1486 bits (3848), Expect = 0.0
Identities = 727/727 (100%), Positives = 727/727 (100%)
Query: 1 MAADSREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQ 60
MAADSREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQ
Sbjct: 1 MAADSREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQ 60
Query: 61 KPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSS 120
KPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSS
Sbjct: 61 KPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSS 120
Query: 121 ASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYG 180
ASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYG
Sbjct: 121 ASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYG 180
Query: 181 SDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEE 240
SDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEE
Sbjct: 181 SDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEE 240
Query: 241 EEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKE 300
EEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKE
Sbjct: 241 EEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKE 300
Query: 301 RKRARGISPIVFDRSGSSASESYAGSEKKHEKLSSSVRAVRKDQTSKLKYVLQDARFFLI 360
RKRARGISPIVFDRSGSSASESYAGSEKKHEKLSSSVRAVRKDQTSKLKYVLQDARFFLI
Sbjct: 301 RKRARGISPIVFDRSGSSASESYAGSEKKHEKLSSSVRAVRKDQTSKLKYVLQDARFFLI 360
Query: 361 KSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARSVILIFSVRESGKFQGFARLSSESH 420
KSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARSVILIFSVRESGKFQGFARLSSESH
Sbjct: 361 KSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARSVILIFSVRESGKFQGFARLSSESH 420
Query: 421 HGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEI 480
HGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEI
Sbjct: 421 HGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEI 480
Query: 481 ELECGTQLCLLFPPDESIDLYQVIHKMRHKRRMHSQPRSRGRPSRREPVRDVGRRRPEDY 540
ELECGTQLCLLFPPDESIDLYQVIHKMRHKRRMHSQPRSRGRPSRREPVRDVGRRRPEDY
Sbjct: 481 ELECGTQLCLLFPPDESIDLYQVIHKMRHKRRMHSQPRSRGRPSRREPVRDVGRRRPEDY 540
Query: 541 DIHNSRKKPRIDYPPEFHQRPGYLKDPRYQEVDRRFSGVRRDVFLNGSYNDYVREFHNMG 600
DIHNSRKKPRIDYPPEFHQRPGYLKDPRYQEVDRRFSGVRRDVFLNGSYNDYVREFHNMG
Sbjct: 541 DIHNSRKKPRIDYPPEFHQRPGYLKDPRYQEVDRRFSGVRRDVFLNGSYNDYVREFHNMG 600
Query: 601 PPPPWQGMPPYPGMEQPPHHPYYQHHAPPPQAHPPYSGHHPVPHEARYRDKRVHDYDMRV 660
PPPPWQGMPPYPGMEQPPHHPYYQHHAPPPQAHPPYSGHHPVPHEARYRDKRVHDYDMRV
Sbjct: 601 PPPPWQGMPPYPGMEQPPHHPYYQHHAPPPQAHPPYSGHHPVPHEARYRDKRVHDYDMRV 660
Query: 661 DDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRG 720
DDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRG
Sbjct: 661 DDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRG 720
Query: 721 ERGRYRR 727
ERGRYRR
Sbjct: 721 ERGRYRR 727
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 1442 bits (3733), Expect = 0.0
Identities = 709/727 (97%), Positives = 709/727 (97%), Gaps = 18/727 (2%)
Query: 1 MAADSREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQ 60
MAADSREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQ
Sbjct: 1 MAADSREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQ 60
Query: 61 KPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSS 120
KPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSS
Sbjct: 61 KPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSS 120
Query: 121 ASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYG 180
ASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYG
Sbjct: 121 ASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYG 180
Query: 181 SDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEE 240
SDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEE
Sbjct: 181 SDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEE 240
Query: 241 EEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKE 300
EEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKE
Sbjct: 241 EEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKE 300
Query: 301 RKRARGISPIVFDRSGSSASESYAGSEKKHEKLSSSVRAVRKDQTSKLKYVLQDARFFLI 360
RKRARGISPIVFDRSGSSASESYA DQTSKLKYVLQDARFFLI
Sbjct: 301 RKRARGISPIVFDRSGSSASESYA------------------DQTSKLKYVLQDARFFLI 342
Query: 361 KSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARSVILIFSVRESGKFQGFARLSSESH 420
KSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARSVILIFSVRESGKFQGFARLSSESH
Sbjct: 343 KSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARSVILIFSVRESGKFQGFARLSSESH 402
Query: 421 HGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEI 480
HGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEI
Sbjct: 403 HGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEI 462
Query: 481 ELECGTQLCLLFPPDESIDLYQVIHKMRHKRRMHSQPRSRGRPSRREPVRDVGRRRPEDY 540
ELECGTQLCLLFPPDESIDLYQVIHKMRHKRRMHSQPRSRGRPSRREPVRDVGRRRPEDY
Sbjct: 463 ELECGTQLCLLFPPDESIDLYQVIHKMRHKRRMHSQPRSRGRPSRREPVRDVGRRRPEDY 522
Query: 541 DIHNSRKKPRIDYPPEFHQRPGYLKDPRYQEVDRRFSGVRRDVFLNGSYNDYVREFHNMG 600
DIHNSRKKPRIDYPPEFHQRPGYLKDPRYQEVDRRFSGVRRDVFLNGSYNDYVREFHNMG
Sbjct: 523 DIHNSRKKPRIDYPPEFHQRPGYLKDPRYQEVDRRFSGVRRDVFLNGSYNDYVREFHNMG 582
Query: 601 PPPPWQGMPPYPGMEQPPHHPYYQHHAPPPQAHPPYSGHHPVPHEARYRDKRVHDYDMRV 660
PPPPWQGMPPYPGMEQPPHHPYYQHHAPPPQAHPPYSGHHPVPHEARYRDKRVHDYDMRV
Sbjct: 583 PPPPWQGMPPYPGMEQPPHHPYYQHHAPPPQAHPPYSGHHPVPHEARYRDKRVHDYDMRV 642
Query: 661 DDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRG 720
DDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRG
Sbjct: 643 DDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRG 702
Query: 721 ERGRYRR 727
ERGRYRR
Sbjct: 703 ERGRYRR 709
>gi|38505213 YTH domain containing 2 [Homo sapiens]
Length = 1430
Score = 130 bits (328), Expect = 3e-30
Identities = 76/180 (42%), Positives = 104/180 (57%), Gaps = 7/180 (3%)
Query: 313 DRSGSSASESYAGSEKKHEKLSSSVRAVRKDQTSKLKYVLQDARFFLIKSNNHENVSLAK 372
DRS S+ +S S S S + K S R+F++KS+N N+ +++
Sbjct: 1246 DRSDQSSLKSTDSSSYPSPCASPSPPSSGKGSKSPSPRPNMPVRYFIMKSSNLRNLEISQ 1305
Query: 373 AKGVWSTLPVNEKKLNLAFRSARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPA 432
KG+WST P NE+KLN AF + V L+FSV+ SG FQGF+R+SSE S W
Sbjct: 1306 QKGIWSTTPSNERKLNRAFWESSIVYLVFSVQGSGHFQGFSRMSSEIGREKSQ-DW---- 1360
Query: 433 GMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLF 492
+ LGGVFK++WI + LPF + HL NPWN++K V+I RDGQE+E G QL L+
Sbjct: 1361 --GSAGLGGVFKVEWIRKESLPFQFAHHLLNPWNDNKKVQISRDGQELEPLVGEQLLQLW 1418
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 91.3 bits (225), Expect = 3e-18
Identities = 86/319 (26%), Positives = 137/319 (42%), Gaps = 45/319 (14%)
Query: 23 VPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNK 82
+P +++ P + +D NE G K+K D+ + K +K ++ P ++V +
Sbjct: 292 IPASEEKAETPTAAEDDNE--GDKKKKDKKKKKGEKEEK----EKEKKKGPSKATVKAMQ 345
Query: 83 RIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKT--------- 133
++ + K EE +R +R + L+A RK + K Q EK
Sbjct: 346 EALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEG 405
Query: 134 -CVRKRDPERRAKSP-TPDGSERIGLEVDRRAS----------RSSQSSKEEVNSEEYGS 181
+ K E RA++ T + G+EV + S + + +++ S+E
Sbjct: 406 KLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSE 465
Query: 182 DHETGSSGSSDEQGNNTENE-----EEGVEEDVEE-----------DEEVE--EDAEEDE 223
E ++ EQG + E E EED E+ DEE E E +
Sbjct: 466 SMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHI 525
Query: 224 EVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDG 283
EV E+ EEEEEEEEEEEE+EE EEEE E+ E + E + + S+ DSG
Sbjct: 526 EVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSK 585
Query: 284 SVRSGSGTDGSDEKKKERK 302
+ S S D D++ KE +
Sbjct: 586 EMSSDSEYDSDDDRTKEER 604
Score = 83.2 bits (204), Expect = 8e-16
Identities = 73/306 (23%), Positives = 132/306 (43%), Gaps = 27/306 (8%)
Query: 6 REEKDGE----LNVLDDILTEVPEQDDELYNPESEQDKN--EKKGSKRKSDRMESTDTKR 59
+E+K G + + + L ++ E+++ E E+ K E + +++ +R+E +R
Sbjct: 330 KEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRER 389
Query: 60 QKPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSS 119
+K R K + +GK T+ + E R+E +L + + + S
Sbjct: 390 KKQKEKER--------------KERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPS 435
Query: 120 SASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIG-LEVDRRASRSSQSSKEEVNSEE 178
S P K + RK+ P++ + E +EV + + + V EE
Sbjct: 436 KDSL-PKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEE 494
Query: 179 YGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEE 238
+ +T +G D + ++ E E VE + E E EE+EE +E+ E+EE EEEE
Sbjct: 495 ---EEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEE 551
Query: 239 EEEEEEEEEEEYEQDER--DQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDE 296
EEE E E E E+DE+ D+K+ G D + S D + D +
Sbjct: 552 EEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKR 611
Query: 297 KKKERK 302
+ ++R+
Sbjct: 612 RIEKRR 617
Score = 59.7 bits (143), Expect = 9e-09
Identities = 56/258 (21%), Positives = 111/258 (43%), Gaps = 28/258 (10%)
Query: 27 DDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNKRIVS 86
DD+ +N ++ K + + S +K D E + +K + R ++ S +++ + S
Sbjct: 139 DDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKK--IKERSRINSSGESGDESDEFLQS 196
Query: 87 TKGKSATEYKNEEYQRSERNKRLDADRKIRL-----SSSASREPYKNQPEKTCVRKRDPE 141
KG+ + N+ DA KI+ + RE K EK +RK +
Sbjct: 197 RKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEK 256
Query: 142 RRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENE 201
++ D S++ E R+ + SK V++ + E + ++ E N + +
Sbjct: 257 EELETGKKDQSKQ--KESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKK 314
Query: 202 EEGVEEDVEEDEEVEEDAE-------------------EDEEVDEDGEEEEEEEEEEEEE 242
++ ++ E EE E++ + E+EE + EEE + EE E
Sbjct: 315 KKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEA 374
Query: 243 EEEEEEEYEQDERDQKEE 260
+ +EEE EQ++R++K++
Sbjct: 375 KRKEEERLEQEKRERKKQ 392
Score = 58.9 bits (141), Expect = 2e-08
Identities = 63/322 (19%), Positives = 131/322 (40%), Gaps = 23/322 (7%)
Query: 6 REEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVH 65
+++ E + DDI + + E EQ+ + KG K+K + + D +
Sbjct: 4 KQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELE 63
Query: 66 SRQLVSKPLSSS--------VSNNKRIVSTKGKS--ATEYKNEEYQRSERNKRLDADRKI 115
L ++ + + NN+ ++K K + K + + ++ + D D K
Sbjct: 64 ELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKS 123
Query: 116 RLSSSASREPYKNQPEKTCVRKRDPERRAKSPTP----DGSERI--GLEVDRRASRSSQS 169
+ ++ E Y + K + + K+ DGSE + + SR + S
Sbjct: 124 KKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSS 183
Query: 170 SKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDG 229
+ S+E+ + ++ G N E+ E + + ++ AE+ E E
Sbjct: 184 GESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKER--ERK 241
Query: 230 EEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEAS----DSGSESVSFTDGSV 285
+ +EE+ + + +E+EE E ++D+ QKE ++ + S D+G S
Sbjct: 242 KRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAET 301
Query: 286 RSGSGTDG-SDEKKKERKRARG 306
+ + D D+KKK++K+ +G
Sbjct: 302 PTAAEDDNEGDKKKKDKKKKKG 323
Score = 57.8 bits (138), Expect = 4e-08
Identities = 55/259 (21%), Positives = 114/259 (44%), Gaps = 27/259 (10%)
Query: 24 PEQDDELYNPESEQDKNEKKGSKRK-----SDRMESTDTKRQKPSVHSRQLVSKPLSSSV 78
P +++E ++ K +KG K+ S+ +E D+K +K + ++ S S
Sbjct: 83 PTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYS---GSDD 139
Query: 79 SNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKR 138
++ + K K + N+++ SE ++ K R ++S E E RK
Sbjct: 140 DDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKG 199
Query: 139 DPERRAKSPTP---------DGSERIGLEVDRRASRSSQSSKE------EVNSEEYGSDH 183
+ + P P D S +I ++A + + K+ ++ + +
Sbjct: 200 QKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEEL 259
Query: 184 ETGSSGSSDEQGNNTENEEEGVEEDVEEDEEV----EEDAEEDEEVDEDGEEEEEEEEEE 239
ETG S ++ + + EEE V+ V D V EE AE ++D E ++++++++
Sbjct: 260 ETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKK 319
Query: 240 EEEEEEEEEEYEQDERDQK 258
+++ E+EE+E E+ + K
Sbjct: 320 KKKGEKEEKEKEKKKGPSK 338
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 89.4 bits (220), Expect = 1e-17
Identities = 71/276 (25%), Positives = 118/276 (42%), Gaps = 30/276 (10%)
Query: 25 EQDDELYNPESEQDKNE--KKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNK 82
E+ D+ Q + E ++ S+R+ DR+E + KR++ +
Sbjct: 127 EEQDKARREWERQKRREMAREHSRRERDRLEQLERKRER--------------------E 166
Query: 83 RIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPER 142
R + + K E K E + ER K +A R++ RE Y ++ K R P R
Sbjct: 167 RKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKV-KASHWSRSPPR 225
Query: 143 RAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEE 202
+ G R ++ ++ R S ++++ E + SS S E EE
Sbjct: 226 PPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE 285
Query: 203 EGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEE-- 260
E EE+ EE EE+ EE+EE +E+ EE E+ EE EEE E +ER+ +
Sbjct: 286 EEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLL 345
Query: 261 ---GNDYDTRSEASDSGSESVSFTDGSVRSGSGTDG 293
+ +D S S+ E V +G+ +S + T+G
Sbjct: 346 VVPESRFDRDSGESEEAEEEVG--EGTPQSSALTEG 379
Score = 75.5 bits (184), Expect = 2e-13
Identities = 68/313 (21%), Positives = 129/313 (41%), Gaps = 27/313 (8%)
Query: 17 DDILTEVPEQDDEL-YNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLS 75
+D + + E+DD L P + + EK ++ R E R K H R+
Sbjct: 70 EDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHERR------- 122
Query: 76 SSVSNNKRIVSTKGKSATEYKNEEYQRSER-NKRLDADRKIRLSSSASREPYKNQPEKTC 134
KR + K+ E++ ++ + R + R + DR +L RE + +K
Sbjct: 123 ------KRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQ 176
Query: 135 VRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQ 194
+++ ERRA+ + R + R R S K + + H + S +
Sbjct: 177 REQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKAS-------HWSRSPPRPPRE 229
Query: 195 GNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEE----EEEEEEEEEEY 250
+ + V+E+ E+ ++ D ++ + + E E EEEEEEEEEE
Sbjct: 230 RFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEE 289
Query: 251 EQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGISP- 309
E+ ++ E + + E ++GS S ++ S S + S+++++E + + P
Sbjct: 290 EEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPE 349
Query: 310 IVFDRSGSSASES 322
FDR + E+
Sbjct: 350 SRFDRDSGESEEA 362
Score = 48.9 bits (115), Expect = 2e-05
Identities = 71/336 (21%), Positives = 131/336 (38%), Gaps = 40/336 (11%)
Query: 7 EEKDG-ELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVH 65
+EKD ++ LD+IL E + ++ ++K E K K DR D+KR S+
Sbjct: 3 DEKDSWKVKTLDEILQEKKRRKEQ-------EEKAEIKRLKNSDDR----DSKRD--SLE 49
Query: 66 SRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREP 125
+L + ++ N+ + + + E + EE RK ++ E
Sbjct: 50 EGELRDHCMEITIRNSPY----RREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKD-EK 104
Query: 126 YKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEE---VNSEEYGSD 182
K + + V++R+ ERR + R E +R + + S+ E + E +
Sbjct: 105 RKEKWKHARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRE 164
Query: 183 HETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEE 242
E EQ E E EE +E E E + + ED ++ +
Sbjct: 165 RERKMREQQKEQREQKERERRA-EERRKEREARREVSAHHRTMREDYSDKVKASHWSRSP 223
Query: 243 EEEEEEEYEQDE------RDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDE 296
E +E + ++ EE + + SDS ++ S S SGSG++ +E
Sbjct: 224 PRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEE 283
Query: 297 KKKERKRARGISPIVFDRSGSSASESYAGSEKKHEK 332
+++E + GS++ ES E++ E+
Sbjct: 284 EEEEE-----------EEEGSTSEESEEEEEEEEEE 308
Score = 36.2 bits (82), Expect = 0.11
Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 8/107 (7%)
Query: 628 PPPQAHPPYSGHHPVPHEARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRE--- 684
PP Q HH + + + K + + R + RR R++ RE
Sbjct: 87 PPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREWERQKRREMAR 146
Query: 685 ----RERDRPRDNRRDRERDRG-RDRERERERLCDRDRDRGERGRYR 726
RERDR R RER+R R++++E+ +R+R ER + R
Sbjct: 147 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKER 193
Score = 36.2 bits (82), Expect = 0.11
Identities = 30/81 (37%), Positives = 40/81 (49%), Gaps = 9/81 (11%)
Query: 644 HEARYRDKRVHDYDMRV-DDFLRRTQAVVSGRRSRPR----ERDRERE---RDRPRDNRR 695
HE R R + D R + RR A RR R R ER RERE R++ ++ R
Sbjct: 119 HERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQRE 178
Query: 696 DRERDRGRDRERERERLCDRD 716
+ER+R R ER +ER R+
Sbjct: 179 QKERER-RAEERRKEREARRE 198
Score = 35.4 bits (80), Expect = 0.19
Identities = 46/214 (21%), Positives = 73/214 (34%), Gaps = 36/214 (16%)
Query: 506 KMRHKRRMHSQPRSRGRPSRREPVRDVGRRRPEDYD-IHNSRKKPRIDYPPEFHQRPGYL 564
+ RH+ R R RRE R+ RR + + + R++ R + QR
Sbjct: 122 RKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKE 181
Query: 565 KDPRYQEVDRRFSGVRRDV-----FLNGSYNDYVREFHNMGPPPPWQGMPPYPGMEQPPH 619
++ R +E R+ RR+V + Y+D V+ H W PP
Sbjct: 182 RERRAEE-RRKEREARREVSAHHRTMREDYSDKVKASH-------WSRSPP--------- 224
Query: 620 HPYYQHHAPPPQAHPPYSGHHPVPHEARYRDKRVHDYDMRVDDFLRRT-----QAVVSGR 674
PP + G PV E + D + D R+T + SG
Sbjct: 225 -------RPPRERFELGDGRKPVKEEKMEERDLLSDL-QDISDSERKTSSAESSSAESGS 276
Query: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDRERE 708
S E + E E + + E + + E E
Sbjct: 277 GSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEE 310
Score = 32.0 bits (71), Expect = 2.1
Identities = 39/156 (25%), Positives = 63/156 (40%), Gaps = 19/156 (12%)
Query: 562 GYLKDPRYQEVDRRFSGVRRDVFLNGSYNDYVREFHNMGPPPPWQGMPPYPGMEQPPHH- 620
G L+D E+ R S RR+ S D E ++ PP Q ++ HH
Sbjct: 51 GELRD-HCMEITIRNSPYRRE----DSMEDRGEEDDSLAIKPPQQ-----MSRKEKVHHR 100
Query: 621 ------PYYQHHAPPPQAHPPYSGHHPVPHEARYRDKRVHDYDMRVDDFLRRTQAVVSGR 674
++H + H H +AR +R +M + R +
Sbjct: 101 KDEKRKEKWKHARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLE 160
Query: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDRERERE 710
R R RER + RE+ + + +++RER R +R +ERE
Sbjct: 161 RKRERER-KMREQQKEQREQKERER-RAEERRKERE 194
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 89.4 bits (220), Expect = 1e-17
Identities = 71/276 (25%), Positives = 118/276 (42%), Gaps = 30/276 (10%)
Query: 25 EQDDELYNPESEQDKNE--KKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNK 82
E+ D+ Q + E ++ S+R+ DR+E + KR++ +
Sbjct: 137 EEQDKARREWERQKRREMAREHSRRERDRLEQLERKRER--------------------E 176
Query: 83 RIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPER 142
R + + K E K E + ER K +A R++ RE Y ++ K R P R
Sbjct: 177 RKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKV-KASHWSRSPPR 235
Query: 143 RAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEE 202
+ G R ++ ++ R S ++++ E + SS S E EE
Sbjct: 236 PPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE 295
Query: 203 EGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEE-- 260
E EE+ EE EE+ EE+EE +E+ EE E+ EE EEE E +ER+ +
Sbjct: 296 EEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLL 355
Query: 261 ---GNDYDTRSEASDSGSESVSFTDGSVRSGSGTDG 293
+ +D S S+ E V +G+ +S + T+G
Sbjct: 356 VVPESRFDRDSGESEEAEEEVG--EGTPQSSALTEG 389
Score = 71.2 bits (173), Expect = 3e-12
Identities = 66/317 (20%), Positives = 128/317 (40%), Gaps = 25/317 (7%)
Query: 17 DDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSS 76
+D + + E+DD L +Q ++K RK D KR++ H +
Sbjct: 70 EDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRK-------DEKRKEKCRHHSHSAEGGKHA 122
Query: 77 SVSNNKRIVSTKGKSATEYKNEEYQRSERNK------RLDADRKIRLSSSASREPYKNQP 130
V + + + + E++R +R + R + DR +L RE +
Sbjct: 123 RVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQ 182
Query: 131 EKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGS 190
+K +++ ERRA+ + R + R R S K + + H + S
Sbjct: 183 QKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKAS-------HWSRSPPR 235
Query: 191 SDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEE----EEEEEEE 246
+ + + V+E+ E+ ++ D ++ + + E E EEEEEEE
Sbjct: 236 PPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE 295
Query: 247 EEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARG 306
EEE E+ ++ E + + E ++GS S ++ S S + S+++++E +
Sbjct: 296 EEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLL 355
Query: 307 ISP-IVFDRSGSSASES 322
+ P FDR + E+
Sbjct: 356 VVPESRFDRDSGESEEA 372
Score = 48.1 bits (113), Expect = 3e-05
Identities = 68/341 (19%), Positives = 133/341 (39%), Gaps = 40/341 (11%)
Query: 7 EEKDG-ELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVH 65
+EKD ++ LD+IL E + ++ ++K E K K DR D+KR S+
Sbjct: 3 DEKDSWKVKTLDEILQEKKRRKEQ-------EEKAEIKRLKNSDDR----DSKRD--SLE 49
Query: 66 SRQLVSKPLSSSVSNN----KRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSA 121
+L + ++ N+ + + +G+ + Q+ R +++ + +
Sbjct: 50 EGELRDHCMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKC 109
Query: 122 SREPYKNQPEKTC-VRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEE---VNSE 177
+ + K V++R+ ERR + R E +R + + S+ E +
Sbjct: 110 RHHSHSAEGGKHARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQL 169
Query: 178 EYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEE 237
E + E EQ E E EE +E E E + + ED ++ +
Sbjct: 170 ERKRERERKMREQQKEQREQKERERRA-EERRKEREARREVSAHHRTMREDYSDKVKASH 228
Query: 238 EEEEEEEEEEEEYEQDE------RDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGT 291
E +E + ++ EE + + SDS ++ S S SGSG+
Sbjct: 229 WSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGS 288
Query: 292 DGSDEKKKERKRARGISPIVFDRSGSSASESYAGSEKKHEK 332
+ +E+++E + GS++ ES E++ E+
Sbjct: 289 EEEEEEEEEE-----------EEEGSTSEESEEEEEEEEEE 318
Score = 36.6 bits (83), Expect = 0.085
Identities = 31/104 (29%), Positives = 47/104 (45%), Gaps = 11/104 (10%)
Query: 624 QHHAPPPQAHPPYSGHHPVPHEARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDR 683
+HH+ H G H E + ++ H R + R + RR RE R
Sbjct: 110 RHHS-----HSAEGGKHARVKEREHERRKRH----REEQDKARREWERQKRREMAREHSR 160
Query: 684 ERERDRPRDNRRDRERDRG-RDRERERERLCDRDRDRGERGRYR 726
RERDR R RER+R R++++E+ +R+R ER + R
Sbjct: 161 -RERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKER 203
Score = 36.2 bits (82), Expect = 0.11
Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 8/90 (8%)
Query: 643 PHEARYRDKRVHDY--DMRVDDFLRRTQAVVSGRRSRPRERD---RERERDRPRDNRRDR 697
P + R ++VH + R + + + G+ +R +ER+ R+R R+ RR+
Sbjct: 87 PPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGKHARVKEREHERRKRHREEQDKARREW 146
Query: 698 ERDRGRDRERERERLCDRDRDRGERGRYRR 727
ER + R+ RE R R+RDR E+ +R
Sbjct: 147 ERQKRREMAREHSR---RERDRLEQLERKR 173
Score = 36.2 bits (82), Expect = 0.11
Identities = 30/81 (37%), Positives = 40/81 (49%), Gaps = 9/81 (11%)
Query: 644 HEARYRDKRVHDYDMRV-DDFLRRTQAVVSGRRSRPR----ERDRERE---RDRPRDNRR 695
HE R R + D R + RR A RR R R ER RERE R++ ++ R
Sbjct: 129 HERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQRE 188
Query: 696 DRERDRGRDRERERERLCDRD 716
+ER+R R ER +ER R+
Sbjct: 189 QKERER-RAEERRKEREARRE 208
Score = 35.4 bits (80), Expect = 0.19
Identities = 46/214 (21%), Positives = 73/214 (34%), Gaps = 36/214 (16%)
Query: 506 KMRHKRRMHSQPRSRGRPSRREPVRDVGRRRPEDYD-IHNSRKKPRIDYPPEFHQRPGYL 564
+ RH+ R R RRE R+ RR + + + R++ R + QR
Sbjct: 132 RKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKE 191
Query: 565 KDPRYQEVDRRFSGVRRDV-----FLNGSYNDYVREFHNMGPPPPWQGMPPYPGMEQPPH 619
++ R +E R+ RR+V + Y+D V+ H W PP
Sbjct: 192 RERRAEE-RRKEREARREVSAHHRTMREDYSDKVKASH-------WSRSPP--------- 234
Query: 620 HPYYQHHAPPPQAHPPYSGHHPVPHEARYRDKRVHDYDMRVDDFLRRT-----QAVVSGR 674
PP + G PV E + D + D R+T + SG
Sbjct: 235 -------RPPRERFELGDGRKPVKEEKMEERDLLSDL-QDISDSERKTSSAESSSAESGS 286
Query: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDRERE 708
S E + E E + + E + + E E
Sbjct: 287 GSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEE 320
Score = 33.9 bits (76), Expect = 0.55
Identities = 34/110 (30%), Positives = 45/110 (40%), Gaps = 11/110 (10%)
Query: 628 PPPQAHPPYSGHHPVPHEARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERD---RE 684
PP Q HH E R R H + R + R+ E+D RE
Sbjct: 87 PPQQMSRKEKVHHR-KDEKRKEKCRHHSHSAEGGKHARVKEREHERRKRHREEQDKARRE 145
Query: 685 RERDRPRDNRRD---RERDR----GRDRERERERLCDRDRDRGERGRYRR 727
ER + R+ R+ RERDR R RERER+ + R ++ R RR
Sbjct: 146 WERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERR 195
Score = 30.8 bits (68), Expect = 4.6
Identities = 26/100 (26%), Positives = 44/100 (44%), Gaps = 6/100 (6%)
Query: 615 EQPPHHPYY----QHHAPPPQAHPPYSGHHPVPHEARYRDKRVHDYDMRVDDFLRRTQAV 670
E+ HH + +H + H H +AR +R +M + R +
Sbjct: 107 EKCRHHSHSAEGGKHARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRL 166
Query: 671 VSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERE 710
R R RER + RE+ + + +++RER R +R +ERE
Sbjct: 167 EQLERKRERER-KMREQQKEQREQKERER-RAEERRKERE 204
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 89.4 bits (220), Expect = 1e-17
Identities = 71/276 (25%), Positives = 118/276 (42%), Gaps = 30/276 (10%)
Query: 25 EQDDELYNPESEQDKNE--KKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNK 82
E+ D+ Q + E ++ S+R+ DR+E + KR++ +
Sbjct: 128 EEQDKARREWERQKRREMAREHSRRERDRLEQLERKRER--------------------E 167
Query: 83 RIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPER 142
R + + K E K E + ER K +A R++ RE Y ++ K R P R
Sbjct: 168 RKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKV-KASHWSRSPPR 226
Query: 143 RAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEE 202
+ G R ++ ++ R S ++++ E + SS S E EE
Sbjct: 227 PPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE 286
Query: 203 EGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEE-- 260
E EE+ EE EE+ EE+EE +E+ EE E+ EE EEE E +ER+ +
Sbjct: 287 EEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLL 346
Query: 261 ---GNDYDTRSEASDSGSESVSFTDGSVRSGSGTDG 293
+ +D S S+ E V +G+ +S + T+G
Sbjct: 347 VVPESRFDRDSGESEEAEEEVG--EGTPQSSALTEG 380
Score = 73.6 bits (179), Expect = 6e-13
Identities = 67/314 (21%), Positives = 131/314 (41%), Gaps = 28/314 (8%)
Query: 17 DDILTEVPEQDDEL-YNPESEQDKNEKKGSKRKSDRMESTDTK-RQKPSVHSRQLVSKPL 74
+D + + E+DD L P + + EK ++ R E + ++K H R+
Sbjct: 70 EDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERR------ 123
Query: 75 SSSVSNNKRIVSTKGKSATEYKNEEYQRSER-NKRLDADRKIRLSSSASREPYKNQPEKT 133
KR + K+ E++ ++ + R + R + DR +L RE + +K
Sbjct: 124 -------KRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKE 176
Query: 134 CVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDE 193
+++ ERRA+ + R + R R S K + + H + S
Sbjct: 177 QREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKAS-------HWSRSPPRPPR 229
Query: 194 QGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEE----EEEEEEEEEE 249
+ + + V+E+ E+ ++ D ++ + + E E EEEEEEEEEE
Sbjct: 230 ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE 289
Query: 250 YEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGISP 309
E+ ++ E + + E ++GS S ++ S S + S+++++E + + P
Sbjct: 290 EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVP 349
Query: 310 -IVFDRSGSSASES 322
FDR + E+
Sbjct: 350 ESRFDRDSGESEEA 363
Score = 48.9 bits (115), Expect = 2e-05
Identities = 68/336 (20%), Positives = 130/336 (38%), Gaps = 39/336 (11%)
Query: 7 EEKDG-ELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVH 65
+EKD ++ LD+IL E + ++ ++K E K K DR D+KR S+
Sbjct: 3 DEKDSWKVKTLDEILQEKKRRKEQ-------EEKAEIKRLKNSDDR----DSKRD--SLE 49
Query: 66 SRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREP 125
+L + ++ N+ + + + E + EE RK ++ +
Sbjct: 50 EGELRDHCMEITIRNSPY----RREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKR 105
Query: 126 YKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEE---VNSEEYGSD 182
+ + + ++R+ ERR + R E +R + + S+ E + E +
Sbjct: 106 KEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRE 165
Query: 183 HETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEE 242
E EQ E E EE +E E E + + ED ++ +
Sbjct: 166 RERKMREQQKEQREQKERERRA-EERRKEREARREVSAHHRTMREDYSDKVKASHWSRSP 224
Query: 243 EEEEEEEYEQDE------RDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDE 296
E +E + ++ EE + + SDS ++ S S SGSG++ +E
Sbjct: 225 PRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEE 284
Query: 297 KKKERKRARGISPIVFDRSGSSASESYAGSEKKHEK 332
+++E + GS++ ES E++ E+
Sbjct: 285 EEEEE-----------EEEGSTSEESEEEEEEEEEE 309
Score = 38.9 bits (89), Expect = 0.017
Identities = 39/209 (18%), Positives = 87/209 (41%), Gaps = 27/209 (12%)
Query: 159 VDRRASRSSQSSKEEV----NSEEYGSDHETGSSGSSDEQ------GNNTENEEEGVEED 208
+ + R Q K E+ NS++ S ++ G + N+ E+ +E+
Sbjct: 17 LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDR 76
Query: 209 VEEDEEV----EEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDY 264
EED+ + + E+V +E+ +E++ +E+E E E + R+++++
Sbjct: 77 GEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARRE 136
Query: 265 DTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYA 324
R + + E S D ++ +++R+R R + ++ E A
Sbjct: 137 WERQKRREMARE---------HSRRERDRLEQLERKRERERKMREQQKEQREQKERERRA 187
Query: 325 GSEKK----HEKLSSSVRAVRKDQTSKLK 349
+K ++S+ R +R+D + K+K
Sbjct: 188 EERRKEREARREVSAHHRTMREDYSDKVK 216
Score = 36.2 bits (82), Expect = 0.11
Identities = 30/81 (37%), Positives = 40/81 (49%), Gaps = 9/81 (11%)
Query: 644 HEARYRDKRVHDYDMRV-DDFLRRTQAVVSGRRSRPR----ERDRERE---RDRPRDNRR 695
HE R R + D R + RR A RR R R ER RERE R++ ++ R
Sbjct: 120 HERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQRE 179
Query: 696 DRERDRGRDRERERERLCDRD 716
+ER+R R ER +ER R+
Sbjct: 180 QKERER-RAEERRKEREARRE 199
Score = 35.4 bits (80), Expect = 0.19
Identities = 30/108 (27%), Positives = 48/108 (44%), Gaps = 9/108 (8%)
Query: 628 PPPQAHPPYSGHHPVPHEARYRDK-RVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRE-- 684
PP Q HH + + + RV + + + R + RR R++ RE
Sbjct: 87 PPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMA 146
Query: 685 -----RERDRPRDNRRDRERDRG-RDRERERERLCDRDRDRGERGRYR 726
RERDR R RER+R R++++E+ +R+R ER + R
Sbjct: 147 REHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKER 194
Score = 35.4 bits (80), Expect = 0.19
Identities = 46/214 (21%), Positives = 73/214 (34%), Gaps = 36/214 (16%)
Query: 506 KMRHKRRMHSQPRSRGRPSRREPVRDVGRRRPEDYD-IHNSRKKPRIDYPPEFHQRPGYL 564
+ RH+ R R RRE R+ RR + + + R++ R + QR
Sbjct: 123 RKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKE 182
Query: 565 KDPRYQEVDRRFSGVRRDV-----FLNGSYNDYVREFHNMGPPPPWQGMPPYPGMEQPPH 619
++ R +E R+ RR+V + Y+D V+ H W PP
Sbjct: 183 RERRAEE-RRKEREARREVSAHHRTMREDYSDKVKASH-------WSRSPP--------- 225
Query: 620 HPYYQHHAPPPQAHPPYSGHHPVPHEARYRDKRVHDYDMRVDDFLRRT-----QAVVSGR 674
PP + G PV E + D + D R+T + SG
Sbjct: 226 -------RPPRERFELGDGRKPVKEEKMEERDLLSDL-QDISDSERKTSSAESSSAESGS 277
Query: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDRERE 708
S E + E E + + E + + E E
Sbjct: 278 GSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEE 311
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 89.4 bits (220), Expect = 1e-17
Identities = 71/276 (25%), Positives = 118/276 (42%), Gaps = 30/276 (10%)
Query: 25 EQDDELYNPESEQDKNE--KKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNK 82
E+ D+ Q + E ++ S+R+ DR+E + KR++ +
Sbjct: 105 EEQDKARREWERQKRREMAREHSRRERDRLEQLERKRER--------------------E 144
Query: 83 RIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPER 142
R + + K E K E + ER K +A R++ RE Y ++ K R P R
Sbjct: 145 RKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKV-KASHWSRSPPR 203
Query: 143 RAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEE 202
+ G R ++ ++ R S ++++ E + SS S E EE
Sbjct: 204 PPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE 263
Query: 203 EGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEE-- 260
E EE+ EE EE+ EE+EE +E+ EE E+ EE EEE E +ER+ +
Sbjct: 264 EEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLL 323
Query: 261 ---GNDYDTRSEASDSGSESVSFTDGSVRSGSGTDG 293
+ +D S S+ E V +G+ +S + T+G
Sbjct: 324 VVPESRFDRDSGESEEAEEEVG--EGTPQSSALTEG 357
Score = 75.5 bits (184), Expect = 2e-13
Identities = 65/312 (20%), Positives = 129/312 (41%), Gaps = 13/312 (4%)
Query: 17 DDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSS 76
+D + + E+DD L +Q ++K RK ++ + R + + K
Sbjct: 36 EDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKER 95
Query: 77 SVSNNKRIVSTKGKSATEYKNEEYQRSER-NKRLDADRKIRLSSSASREPYKNQPEKTCV 135
KR + K+ E++ ++ + R + R + DR +L RE + +K
Sbjct: 96 EHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQR 155
Query: 136 RKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQG 195
+++ ERRA+ + R + R R S K + + H + S +
Sbjct: 156 EQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKAS-------HWSRSPPRPPRER 208
Query: 196 NNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEE----EEEEEEEEEEYE 251
+ + V+E+ E+ ++ D ++ + + E E EEEEEEEEEE E
Sbjct: 209 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 268
Query: 252 QDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGISP-I 310
+ ++ E + + E ++GS S ++ S S + S+++++E + + P
Sbjct: 269 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES 328
Query: 311 VFDRSGSSASES 322
FDR + E+
Sbjct: 329 RFDRDSGESEEA 340
Score = 36.6 bits (83), Expect = 0.085
Identities = 47/171 (27%), Positives = 74/171 (43%), Gaps = 22/171 (12%)
Query: 562 GYLKDPRYQEVDRRFSGVRRDVFLNGSYNDYVREFHNMGPPPPWQGMPPYPGMEQPPHHP 621
G L+D R E+ R S RR+ S D E ++ PP Q ++ HH
Sbjct: 17 GELRDHR-MEITIRNSPYRRE----DSMEDRGEEDDSLAIKPPQQ-----MSRKEKVHHR 66
Query: 622 YYQHHAPPPQ--AHPPYSGHHPVPHEARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPR 679
+ + +H G H AR ++K +++ R + +A R + R
Sbjct: 67 KDEKRKEKRRHRSHSAEGGKH-----ARVKEKE-REHERRKRHREEQDKARREWERQKRR 120
Query: 680 ERDRE---RERDRPRDNRRDRERDRG-RDRERERERLCDRDRDRGERGRYR 726
E RE RERDR R RER+R R++++E+ +R+R ER + R
Sbjct: 121 EMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKER 171
Score = 35.4 bits (80), Expect = 0.19
Identities = 46/214 (21%), Positives = 73/214 (34%), Gaps = 36/214 (16%)
Query: 506 KMRHKRRMHSQPRSRGRPSRREPVRDVGRRRPEDYD-IHNSRKKPRIDYPPEFHQRPGYL 564
+ RH+ R R RRE R+ RR + + + R++ R + QR
Sbjct: 100 RKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKE 159
Query: 565 KDPRYQEVDRRFSGVRRDV-----FLNGSYNDYVREFHNMGPPPPWQGMPPYPGMEQPPH 619
++ R +E R+ RR+V + Y+D V+ H W PP
Sbjct: 160 RERRAEE-RRKEREARREVSAHHRTMREDYSDKVKASH-------WSRSPP--------- 202
Query: 620 HPYYQHHAPPPQAHPPYSGHHPVPHEARYRDKRVHDYDMRVDDFLRRT-----QAVVSGR 674
PP + G PV E + D + D R+T + SG
Sbjct: 203 -------RPPRERFELGDGRKPVKEEKMEERDLLSDL-QDISDSERKTSSAESSSAESGS 254
Query: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDRERE 708
S E + E E + + E + + E E
Sbjct: 255 GSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEE 288
Score = 34.7 bits (78), Expect = 0.32
Identities = 31/111 (27%), Positives = 49/111 (44%), Gaps = 26/111 (23%)
Query: 643 PHEARYRDKRVHDY--DMRVDDFLRRTQAVVSGRRSRPRERDRERERDR----------- 689
P + R ++VH + R + R+ + G+ +R +E++RE ER +
Sbjct: 53 PPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARR 112
Query: 690 --PRDNRRD-------RERDR----GRDRERERERLCDRDRDRGERGRYRR 727
R RR+ RERDR R RERER+ + R ++ R RR
Sbjct: 113 EWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERR 163
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 89.4 bits (220), Expect = 1e-17
Identities = 71/276 (25%), Positives = 118/276 (42%), Gaps = 30/276 (10%)
Query: 25 EQDDELYNPESEQDKNE--KKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNK 82
E+ D+ Q + E ++ S+R+ DR+E + KR++ +
Sbjct: 94 EEQDKARREWERQKRREMAREHSRRERDRLEQLERKRER--------------------E 133
Query: 83 RIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPER 142
R + + K E K E + ER K +A R++ RE Y ++ K R P R
Sbjct: 134 RKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKV-KASHWSRSPPR 192
Query: 143 RAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEE 202
+ G R ++ ++ R S ++++ E + SS S E EE
Sbjct: 193 PPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE 252
Query: 203 EGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEE-- 260
E EE+ EE EE+ EE+EE +E+ EE E+ EE EEE E +ER+ +
Sbjct: 253 EEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLL 312
Query: 261 ---GNDYDTRSEASDSGSESVSFTDGSVRSGSGTDG 293
+ +D S S+ E V +G+ +S + T+G
Sbjct: 313 VVPESRFDRDSGESEEAEEEVG--EGTPQSSALTEG 346
Score = 73.6 bits (179), Expect = 6e-13
Identities = 67/314 (21%), Positives = 131/314 (41%), Gaps = 28/314 (8%)
Query: 17 DDILTEVPEQDDEL-YNPESEQDKNEKKGSKRKSDRMESTDTK-RQKPSVHSRQLVSKPL 74
+D + + E+DD L P + + EK ++ R E + ++K H R+
Sbjct: 36 EDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERR------ 89
Query: 75 SSSVSNNKRIVSTKGKSATEYKNEEYQRSER-NKRLDADRKIRLSSSASREPYKNQPEKT 133
KR + K+ E++ ++ + R + R + DR +L RE + +K
Sbjct: 90 -------KRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKE 142
Query: 134 CVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDE 193
+++ ERRA+ + R + R R S K + + H + S
Sbjct: 143 QREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKAS-------HWSRSPPRPPR 195
Query: 194 QGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEE----EEEEEEEEEE 249
+ + + V+E+ E+ ++ D ++ + + E E EEEEEEEEEE
Sbjct: 196 ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE 255
Query: 250 YEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGISP 309
E+ ++ E + + E ++GS S ++ S S + S+++++E + + P
Sbjct: 256 EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVP 315
Query: 310 -IVFDRSGSSASES 322
FDR + E+
Sbjct: 316 ESRFDRDSGESEEA 329
Score = 43.1 bits (100), Expect = 0.001
Identities = 58/301 (19%), Positives = 107/301 (35%), Gaps = 56/301 (18%)
Query: 32 NPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNKRIVSTKGKS 91
+P +D E +G + S ++ +K VH R+ K+ K K
Sbjct: 31 SPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRK-------DEKRKEKKHARVKEKE 83
Query: 92 ATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDG 151
+ + ++ + R + +R+ R + + + RKR+ ER+ + +
Sbjct: 84 REHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQ 143
Query: 152 SERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEE 211
E+ R R+ + KE E + H T SD+ V+
Sbjct: 144 REQ-----KERERRAEERRKEREARREVSAHHRTMREDYSDK---------------VKA 183
Query: 212 DEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEAS 271
E E G+ + +EE+ EE RD + D S
Sbjct: 184 SHWSRSPPRPPRERFELGDGRKPVKEEKMEE------------RDLLSDLQDI------S 225
Query: 272 DSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYAGSEKKHE 331
DS ++ S S SGSG++ +E+++E + GS++ ES E++ E
Sbjct: 226 DSERKTSSAESSSAESGSGSEEEEEEEEEE-----------EEEGSTSEESEEEEEEEEE 274
Query: 332 K 332
+
Sbjct: 275 E 275
Score = 36.6 bits (83), Expect = 0.085
Identities = 48/163 (29%), Positives = 66/163 (40%), Gaps = 22/163 (13%)
Query: 562 GYLKDPRYQEVDRRFSGVRRDVFLNGSYNDYVREFHNMGPPPPWQGMPPYPGMEQPPHHP 621
G L+D R E+ R S RR+ S D E ++ PP Q ++ HH
Sbjct: 17 GELRDHR-MEITIRNSPYRRE----DSMEDRGEEDDSLAIKPPQQ-----MSRKEKVHHR 66
Query: 622 YYQHHAPPPQAHPPYSGHHPVPHEARYRDKRVHDYDMRV-DDFLRRTQAVVSGRRSRPR- 679
+ A HE R R + D R + RR A RR R R
Sbjct: 67 KDEKRKEKKHARVKEKERE---HERRKRHREEQDKARREWERQKRREMAREHSRRERDRL 123
Query: 680 ---ERDRERE---RDRPRDNRRDRERDRGRDRERERERLCDRD 716
ER RERE R++ ++ R +ER+R R ER +ER R+
Sbjct: 124 EQLERKRERERKMREQQKEQREQKERER-RAEERRKEREARRE 165
Score = 36.6 bits (83), Expect = 0.085
Identities = 31/162 (19%), Positives = 71/162 (43%), Gaps = 17/162 (10%)
Query: 196 NNTENEEEGVEEDVEEDEEV----EEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYE 251
N+ E+ +E+ EED+ + + E+V +E+ +E++ +E+E E E
Sbjct: 30 NSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERR 89
Query: 252 QDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGISPIV 311
+ R+++++ R + + E S D ++ +++R+R R +
Sbjct: 90 KRHREEQDKARREWERQKRREMARE---------HSRRERDRLEQLERKRERERKMREQQ 140
Query: 312 FDRSGSSASESYAGSEKK----HEKLSSSVRAVRKDQTSKLK 349
++ E A +K ++S+ R +R+D + K+K
Sbjct: 141 KEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVK 182
Score = 35.4 bits (80), Expect = 0.19
Identities = 30/108 (27%), Positives = 48/108 (44%), Gaps = 9/108 (8%)
Query: 628 PPPQAHPPYSGHHPVPHEARYRDK-RVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRE-- 684
PP Q HH + + + RV + + + R + RR R++ RE
Sbjct: 53 PPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMA 112
Query: 685 -----RERDRPRDNRRDRERDRG-RDRERERERLCDRDRDRGERGRYR 726
RERDR R RER+R R++++E+ +R+R ER + R
Sbjct: 113 REHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKER 160
Score = 35.4 bits (80), Expect = 0.19
Identities = 46/214 (21%), Positives = 73/214 (34%), Gaps = 36/214 (16%)
Query: 506 KMRHKRRMHSQPRSRGRPSRREPVRDVGRRRPEDYD-IHNSRKKPRIDYPPEFHQRPGYL 564
+ RH+ R R RRE R+ RR + + + R++ R + QR
Sbjct: 89 RKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKE 148
Query: 565 KDPRYQEVDRRFSGVRRDV-----FLNGSYNDYVREFHNMGPPPPWQGMPPYPGMEQPPH 619
++ R +E R+ RR+V + Y+D V+ H W PP
Sbjct: 149 RERRAEE-RRKEREARREVSAHHRTMREDYSDKVKASH-------WSRSPP--------- 191
Query: 620 HPYYQHHAPPPQAHPPYSGHHPVPHEARYRDKRVHDYDMRVDDFLRRT-----QAVVSGR 674
PP + G PV E + D + D R+T + SG
Sbjct: 192 -------RPPRERFELGDGRKPVKEEKMEERDLLSDL-QDISDSERKTSSAESSSAESGS 243
Query: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDRERE 708
S E + E E + + E + + E E
Sbjct: 244 GSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEE 277
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 89.4 bits (220), Expect = 1e-17
Identities = 71/276 (25%), Positives = 118/276 (42%), Gaps = 30/276 (10%)
Query: 25 EQDDELYNPESEQDKNE--KKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNK 82
E+ D+ Q + E ++ S+R+ DR+E + KR++ +
Sbjct: 139 EEQDKARREWERQKRREMAREHSRRERDRLEQLERKRER--------------------E 178
Query: 83 RIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPER 142
R + + K E K E + ER K +A R++ RE Y ++ K R P R
Sbjct: 179 RKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKV-KASHWSRSPPR 237
Query: 143 RAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEE 202
+ G R ++ ++ R S ++++ E + SS S E EE
Sbjct: 238 PPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE 297
Query: 203 EGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEE-- 260
E EE+ EE EE+ EE+EE +E+ EE E+ EE EEE E +ER+ +
Sbjct: 298 EEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLL 357
Query: 261 ---GNDYDTRSEASDSGSESVSFTDGSVRSGSGTDG 293
+ +D S S+ E V +G+ +S + T+G
Sbjct: 358 VVPESRFDRDSGESEEAEEEVG--EGTPQSSALTEG 391
Score = 75.5 bits (184), Expect = 2e-13
Identities = 65/312 (20%), Positives = 129/312 (41%), Gaps = 13/312 (4%)
Query: 17 DDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSS 76
+D + + E+DD L +Q ++K RK ++ + R + + K
Sbjct: 70 EDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKER 129
Query: 77 SVSNNKRIVSTKGKSATEYKNEEYQRSER-NKRLDADRKIRLSSSASREPYKNQPEKTCV 135
KR + K+ E++ ++ + R + R + DR +L RE + +K
Sbjct: 130 EHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQR 189
Query: 136 RKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQG 195
+++ ERRA+ + R + R R S K + + H + S +
Sbjct: 190 EQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKAS-------HWSRSPPRPPRER 242
Query: 196 NNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEE----EEEEEEEEEEYE 251
+ + V+E+ E+ ++ D ++ + + E E EEEEEEEEEE E
Sbjct: 243 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 302
Query: 252 QDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGISP-I 310
+ ++ E + + E ++GS S ++ S S + S+++++E + + P
Sbjct: 303 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES 362
Query: 311 VFDRSGSSASES 322
FDR + E+
Sbjct: 363 RFDRDSGESEEA 374
Score = 51.6 bits (122), Expect = 3e-06
Identities = 71/337 (21%), Positives = 132/337 (39%), Gaps = 30/337 (8%)
Query: 7 EEKDG-ELNVLDDILTEVPEQDDELYNPESEQDKN-EKKGSKRKSDRMESTDTKRQKPSV 64
+EKD ++ LD+IL E + ++ E ++ KN + + SKR D +E + + + +
Sbjct: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKR--DSLEEGELRDHRMEI 60
Query: 65 HSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASRE 124
R + S + S K + +E ++++ R+ R S SA
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHR-SHSAEGG 119
Query: 125 PYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEE---VNSEEYGS 181
+ EK +R+ ERR + R E +R + + S+ E + E
Sbjct: 120 KHARVKEK----EREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKR 175
Query: 182 DHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEE 241
+ E EQ E E EE +E E E + + ED ++ +
Sbjct: 176 ERERKMREQQKEQREQKERERRA-EERRKEREARREVSAHHRTMREDYSDKVKASHWSRS 234
Query: 242 EEEEEEEEYEQDE------RDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSD 295
E +E + ++ EE + + SDS ++ S S SGSG++ +
Sbjct: 235 PPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEE 294
Query: 296 EKKKERKRARGISPIVFDRSGSSASESYAGSEKKHEK 332
E+++E + GS++ ES E++ E+
Sbjct: 295 EEEEEE-----------EEEGSTSEESEEEEEEEEEE 320
Score = 36.6 bits (83), Expect = 0.085
Identities = 47/171 (27%), Positives = 74/171 (43%), Gaps = 22/171 (12%)
Query: 562 GYLKDPRYQEVDRRFSGVRRDVFLNGSYNDYVREFHNMGPPPPWQGMPPYPGMEQPPHHP 621
G L+D R E+ R S RR+ S D E ++ PP Q ++ HH
Sbjct: 51 GELRDHR-MEITIRNSPYRRE----DSMEDRGEEDDSLAIKPPQQ-----MSRKEKVHHR 100
Query: 622 YYQHHAPPPQ--AHPPYSGHHPVPHEARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPR 679
+ + +H G H AR ++K +++ R + +A R + R
Sbjct: 101 KDEKRKEKRRHRSHSAEGGKH-----ARVKEKE-REHERRKRHREEQDKARREWERQKRR 154
Query: 680 ERDRE---RERDRPRDNRRDRERDRG-RDRERERERLCDRDRDRGERGRYR 726
E RE RERDR R RER+R R++++E+ +R+R ER + R
Sbjct: 155 EMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKER 205
Score = 35.4 bits (80), Expect = 0.19
Identities = 46/214 (21%), Positives = 73/214 (34%), Gaps = 36/214 (16%)
Query: 506 KMRHKRRMHSQPRSRGRPSRREPVRDVGRRRPEDYD-IHNSRKKPRIDYPPEFHQRPGYL 564
+ RH+ R R RRE R+ RR + + + R++ R + QR
Sbjct: 134 RKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKE 193
Query: 565 KDPRYQEVDRRFSGVRRDV-----FLNGSYNDYVREFHNMGPPPPWQGMPPYPGMEQPPH 619
++ R +E R+ RR+V + Y+D V+ H W PP
Sbjct: 194 RERRAEE-RRKEREARREVSAHHRTMREDYSDKVKASH-------WSRSPP--------- 236
Query: 620 HPYYQHHAPPPQAHPPYSGHHPVPHEARYRDKRVHDYDMRVDDFLRRT-----QAVVSGR 674
PP + G PV E + D + D R+T + SG
Sbjct: 237 -------RPPRERFELGDGRKPVKEEKMEERDLLSDL-QDISDSERKTSSAESSSAESGS 288
Query: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDRERE 708
S E + E E + + E + + E E
Sbjct: 289 GSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEE 322
Score = 34.7 bits (78), Expect = 0.32
Identities = 31/111 (27%), Positives = 49/111 (44%), Gaps = 26/111 (23%)
Query: 643 PHEARYRDKRVHDY--DMRVDDFLRRTQAVVSGRRSRPRERDRERERDR----------- 689
P + R ++VH + R + R+ + G+ +R +E++RE ER +
Sbjct: 87 PPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARR 146
Query: 690 --PRDNRRD-------RERDR----GRDRERERERLCDRDRDRGERGRYRR 727
R RR+ RERDR R RERER+ + R ++ R RR
Sbjct: 147 EWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERR 197
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 87.0 bits (214), Expect = 5e-17
Identities = 79/344 (22%), Positives = 150/344 (43%), Gaps = 39/344 (11%)
Query: 18 DILTE---VPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPL 74
D++ E P + + P+ E + EK+G R + + + S S + S
Sbjct: 477 DVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSY 536
Query: 75 SSSVSNNKRIVSTKGKSATEYKNEEYQRSE-------RNKRLDADRKIRLSSSASREPYK 127
SSS +++ T +S++ + + + RS R++ R+I++ S+ +R +
Sbjct: 537 SSSSGSSR----TSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIR 592
Query: 128 NQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGS 187
++ RR +SP+ + DRR +R+S+S + +
Sbjct: 593 DRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKID--------- 643
Query: 188 SGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEE 247
D++GN + N + E E++ + E D++ + +E E E+++ +E+++ EE
Sbjct: 644 ----DQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREE 699
Query: 248 EEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGI 307
++++ +D + + R+ S SGS SV +R S D K+ K+ G
Sbjct: 700 KDFKFSSQDDRLKRKRESERT-FSRSGSISVKI----IRHDSRQDSKKSTTKDSKKHSG- 753
Query: 308 SPIVFDRSGSSASESYAGSEKKHEK--LSSSVRAVRKDQTSKLK 349
D SG S+SES S++K K S R+V K Q S K
Sbjct: 754 ----SDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKK 793
Score = 45.4 bits (106), Expect = 2e-04
Identities = 68/349 (19%), Positives = 128/349 (36%), Gaps = 52/349 (14%)
Query: 34 ESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSAT 93
E + + +KK K + ++ S +K++K + + P + +
Sbjct: 241 EKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGP--------------RLPQRS 286
Query: 94 EYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSE 153
++ ++E + N + K+ S S + + PE T + + E + T
Sbjct: 287 KFDSDEEEEDTENVEAASSGKVTRSPSPVPQEEHSDPEMT---EEEKEYQMMLLTKMLLT 343
Query: 154 RIGLEV----------DRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEE 203
I L+V D + +K+ S S G G + E +
Sbjct: 344 EILLDVTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDR 403
Query: 204 GVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEE---YEQDERDQKEE 260
G E +DEE+ + +E E+E++ +++ EEE+++ E E +E KE+
Sbjct: 404 GSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQ 463
Query: 261 GN---------DYDTRSEASDSGSESVSFTD-----------GSVRSGSGTDGSDEKKKE 300
+ D D +E + +E+ S + G RSGS + GS
Sbjct: 464 NSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSR 523
Query: 301 RKRARGI--SPIVFDRSGSSASESYAGSEKKHEKLSSSVRAVRKDQTSK 347
S SGSS + S + S K+ ++ S S K + S+
Sbjct: 524 TSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSR 572
Score = 42.0 bits (97), Expect = 0.002
Identities = 42/185 (22%), Positives = 83/185 (44%), Gaps = 37/185 (20%)
Query: 175 NSEEYGSDHETGSSGSSDEQGNNTENEEEGV------EEDVEEDEEVEEDAEEDEEVDED 228
+SE+ SD + SS + DE+ + +++ E+ + D+++EE+ ++ E V ++
Sbjct: 395 DSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKE 454
Query: 229 GEEEEEEEEE----------------EEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASD 272
E +E+ E++ E + +++ KE+ +RS +S
Sbjct: 455 MNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSS 514
Query: 273 SGSES-----------VSFTDGSVRSGSG--TDGSDEKKKERKRARGISPIVFDRSGSSA 319
SGS S VS + S SGS + S K++++ +R SP + ++ S
Sbjct: 515 SGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTI--KARRSR 572
Query: 320 SESYA 324
S SY+
Sbjct: 573 SRSYS 577
Score = 38.9 bits (89), Expect = 0.017
Identities = 25/81 (30%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Query: 646 ARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDR 705
+R R + R + RR + + R+R + RDR R + R R R R+R
Sbjct: 559 SRSRSPTIKARRSRSRSYSRRIK--IESNRARVKIRDRRRSNRNSIERERRRNRSPSRER 616
Query: 706 ERERERLCDRDRDRGERGRYR 726
R R R DR +R R R R
Sbjct: 617 RRSRSRSRDRRTNRASRSRSR 637
Score = 36.2 bits (82), Expect = 0.11
Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 27/80 (33%)
Query: 674 RRSRPRERDRERERDRPRDNR-----RDRERDRGR----------------------DRE 706
RR+R R+R R R R RD R R R RDR + +R+
Sbjct: 607 RRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERK 666
Query: 707 RERERLCDRDRDRGERGRYR 726
+ER R D+DR + ++ R R
Sbjct: 667 KERSRSIDKDRKKKDKERER 686
Score = 35.8 bits (81), Expect = 0.14
Identities = 19/74 (25%), Positives = 41/74 (55%), Gaps = 9/74 (12%)
Query: 646 ARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDN---RRDRERDRG 702
+R RD+R ++DD + +E++R++ER R D ++D+ER+R
Sbjct: 634 SRSRDRR------KIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKERERE 687
Query: 703 RDRERERERLCDRD 716
+D+ +E+++ ++D
Sbjct: 688 QDKRKEKQKREEKD 701
Score = 34.3 bits (77), Expect = 0.42
Identities = 21/52 (40%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Query: 665 RRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDR-GRDRERERERLCDR 715
RR S R R R R RER R R RDR +R R R R+R ++ D+
Sbjct: 594 RRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQ 645
Score = 32.3 bits (72), Expect = 1.6
Identities = 35/142 (24%), Positives = 53/142 (37%), Gaps = 23/142 (16%)
Query: 597 HNMGPPPPWQGMPPYPGMEQ-------PP----HHPYYQHHAPPPQAHPPYSGHHPVPHE 645
HN G PP + P + PP H PY+Q P P A P P
Sbjct: 147 HNFGGPPDNFAVGPVNQFDYQHGAAFGPPQGGFHPPYWQPGPPGPPAPPQNRRERPSSFR 206
Query: 646 ARYRDK---RVHDYDMRVDDFLRRTQA--VVSGRRSRPRERDRERERDRPRDNRRDRERD 700
R R V ++D RRT + G RE+ ++ E++R E+
Sbjct: 207 DRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKER-------MEQQ 259
Query: 701 RGRDRERERERLCDRDRDRGER 722
R + ++E++ D + G R
Sbjct: 260 RSQLSKKEKKATEDAEGGDGPR 281
Score = 30.8 bits (68), Expect = 4.6
Identities = 32/151 (21%), Positives = 59/151 (39%), Gaps = 12/151 (7%)
Query: 172 EEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEE 231
+++ E+ ++ T + N+ + E E D + E + E V E +E
Sbjct: 439 KQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKE 498
Query: 232 EEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGT 291
+E+E++ ++ T S +S S S S + GS R+ S
Sbjct: 499 HKEKEKQGRS---------RSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSS-- 547
Query: 292 DGSDEKKKERKRARGISPIVFDRSGSSASES 322
S K++++ +R SP + R S S S
Sbjct: 548 -RSSSPKRKKRHSRSRSPTIKARRSRSRSYS 577
Score = 30.4 bits (67), Expect = 6.1
Identities = 14/55 (25%), Positives = 32/55 (58%), Gaps = 5/55 (9%)
Query: 666 RTQAVVSGRRSRPRERDRERERDRPRDNRRDRE-----RDRGRDRERERERLCDR 715
R++++ R+ + +ER+RE+++ + + R +++ +D R+RE ER R
Sbjct: 669 RSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSR 723
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 87.0 bits (214), Expect = 5e-17
Identities = 79/344 (22%), Positives = 150/344 (43%), Gaps = 39/344 (11%)
Query: 18 DILTE---VPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPL 74
D++ E P + + P+ E + EK+G R + + + S S + S
Sbjct: 477 DVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSY 536
Query: 75 SSSVSNNKRIVSTKGKSATEYKNEEYQRSE-------RNKRLDADRKIRLSSSASREPYK 127
SSS +++ T +S++ + + + RS R++ R+I++ S+ +R +
Sbjct: 537 SSSSGSSR----TSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIR 592
Query: 128 NQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGS 187
++ RR +SP+ + DRR +R+S+S + +
Sbjct: 593 DRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKID--------- 643
Query: 188 SGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEE 247
D++GN + N + E E++ + E D++ + +E E E+++ +E+++ EE
Sbjct: 644 ----DQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREE 699
Query: 248 EEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGI 307
++++ +D + + R+ S SGS SV +R S D K+ K+ G
Sbjct: 700 KDFKFSSQDDRLKRKRESERT-FSRSGSISVKI----IRHDSRQDSKKSTTKDSKKHSG- 753
Query: 308 SPIVFDRSGSSASESYAGSEKKHEK--LSSSVRAVRKDQTSKLK 349
D SG S+SES S++K K S R+V K Q S K
Sbjct: 754 ----SDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKK 793
Score = 45.4 bits (106), Expect = 2e-04
Identities = 68/349 (19%), Positives = 128/349 (36%), Gaps = 52/349 (14%)
Query: 34 ESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSAT 93
E + + +KK K + ++ S +K++K + + P + +
Sbjct: 241 EKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGP--------------RLPQRS 286
Query: 94 EYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSE 153
++ ++E + N + K+ S S + + PE T + + E + T
Sbjct: 287 KFDSDEEEEDTENVEAASSGKVTRSPSPVPQEEHSDPEMT---EEEKEYQMMLLTKMLLT 343
Query: 154 RIGLEV----------DRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEE 203
I L+V D + +K+ S S G G + E +
Sbjct: 344 EILLDVTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDR 403
Query: 204 GVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEE---YEQDERDQKEE 260
G E +DEE+ + +E E+E++ +++ EEE+++ E E +E KE+
Sbjct: 404 GSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQ 463
Query: 261 GN---------DYDTRSEASDSGSESVSFTD-----------GSVRSGSGTDGSDEKKKE 300
+ D D +E + +E+ S + G RSGS + GS
Sbjct: 464 NSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSR 523
Query: 301 RKRARGI--SPIVFDRSGSSASESYAGSEKKHEKLSSSVRAVRKDQTSK 347
S SGSS + S + S K+ ++ S S K + S+
Sbjct: 524 TSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSR 572
Score = 42.0 bits (97), Expect = 0.002
Identities = 42/185 (22%), Positives = 83/185 (44%), Gaps = 37/185 (20%)
Query: 175 NSEEYGSDHETGSSGSSDEQGNNTENEEEGV------EEDVEEDEEVEEDAEEDEEVDED 228
+SE+ SD + SS + DE+ + +++ E+ + D+++EE+ ++ E V ++
Sbjct: 395 DSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKE 454
Query: 229 GEEEEEEEEE----------------EEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASD 272
E +E+ E++ E + +++ KE+ +RS +S
Sbjct: 455 MNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSS 514
Query: 273 SGSES-----------VSFTDGSVRSGSG--TDGSDEKKKERKRARGISPIVFDRSGSSA 319
SGS S VS + S SGS + S K++++ +R SP + ++ S
Sbjct: 515 SGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTI--KARRSR 572
Query: 320 SESYA 324
S SY+
Sbjct: 573 SRSYS 577
Score = 38.9 bits (89), Expect = 0.017
Identities = 25/81 (30%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Query: 646 ARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDR 705
+R R + R + RR + + R+R + RDR R + R R R R+R
Sbjct: 559 SRSRSPTIKARRSRSRSYSRRIK--IESNRARVKIRDRRRSNRNSIERERRRNRSPSRER 616
Query: 706 ERERERLCDRDRDRGERGRYR 726
R R R DR +R R R R
Sbjct: 617 RRSRSRSRDRRTNRASRSRSR 637
Score = 36.2 bits (82), Expect = 0.11
Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 27/80 (33%)
Query: 674 RRSRPRERDRERERDRPRDNR-----RDRERDRGR----------------------DRE 706
RR+R R+R R R R RD R R R RDR + +R+
Sbjct: 607 RRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERK 666
Query: 707 RERERLCDRDRDRGERGRYR 726
+ER R D+DR + ++ R R
Sbjct: 667 KERSRSIDKDRKKKDKERER 686
Score = 35.8 bits (81), Expect = 0.14
Identities = 19/74 (25%), Positives = 41/74 (55%), Gaps = 9/74 (12%)
Query: 646 ARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDN---RRDRERDRG 702
+R RD+R ++DD + +E++R++ER R D ++D+ER+R
Sbjct: 634 SRSRDRR------KIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKERERE 687
Query: 703 RDRERERERLCDRD 716
+D+ +E+++ ++D
Sbjct: 688 QDKRKEKQKREEKD 701
Score = 34.3 bits (77), Expect = 0.42
Identities = 21/52 (40%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Query: 665 RRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDR-GRDRERERERLCDR 715
RR S R R R R RER R R RDR +R R R R+R ++ D+
Sbjct: 594 RRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQ 645
Score = 32.3 bits (72), Expect = 1.6
Identities = 35/142 (24%), Positives = 53/142 (37%), Gaps = 23/142 (16%)
Query: 597 HNMGPPPPWQGMPPYPGMEQ-------PP----HHPYYQHHAPPPQAHPPYSGHHPVPHE 645
HN G PP + P + PP H PY+Q P P A P P
Sbjct: 147 HNFGGPPDNFAVGPVNQFDYQHGAAFGPPQGGFHPPYWQPGPPGPPAPPQNRRERPSSFR 206
Query: 646 ARYRDK---RVHDYDMRVDDFLRRTQA--VVSGRRSRPRERDRERERDRPRDNRRDRERD 700
R R V ++D RRT + G RE+ ++ E++R E+
Sbjct: 207 DRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKER-------MEQQ 259
Query: 701 RGRDRERERERLCDRDRDRGER 722
R + ++E++ D + G R
Sbjct: 260 RSQLSKKEKKATEDAEGGDGPR 281
Score = 30.8 bits (68), Expect = 4.6
Identities = 32/151 (21%), Positives = 59/151 (39%), Gaps = 12/151 (7%)
Query: 172 EEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEE 231
+++ E+ ++ T + N+ + E E D + E + E V E +E
Sbjct: 439 KQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKE 498
Query: 232 EEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGT 291
+E+E++ ++ T S +S S S S + GS R+ S
Sbjct: 499 HKEKEKQGRS---------RSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSS-- 547
Query: 292 DGSDEKKKERKRARGISPIVFDRSGSSASES 322
S K++++ +R SP + R S S S
Sbjct: 548 -RSSSPKRKKRHSRSRSPTIKARRSRSRSYS 577
Score = 30.4 bits (67), Expect = 6.1
Identities = 14/55 (25%), Positives = 32/55 (58%), Gaps = 5/55 (9%)
Query: 666 RTQAVVSGRRSRPRERDRERERDRPRDNRRDRE-----RDRGRDRERERERLCDR 715
R++++ R+ + +ER+RE+++ + + R +++ +D R+RE ER R
Sbjct: 669 RSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSR 723
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 85.1 bits (209), Expect = 2e-16
Identities = 70/270 (25%), Positives = 115/270 (42%), Gaps = 21/270 (7%)
Query: 36 EQDKNEKKGSKRKSDRMESTDTKRQKPSV-------HSRQLVSKPLSSSVSNNKRIVSTK 88
EQDK ++ ++K M ++R++ + QL K +R + +
Sbjct: 129 EQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQLERK------RERERKMREQ 182
Query: 89 GKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPT 148
K E K E + ER K +A R++ RE Y ++ K R P R +
Sbjct: 183 QKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKV-KASHWSRSPPRPPRERF 241
Query: 149 PDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEED 208
G R ++ ++ R S ++++ E + SS S E EEE EE+
Sbjct: 242 ELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE 301
Query: 209 VEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEE-----GND 263
EE EE+ EE+EE +E+ EE E+ EE EEE E +ER+ + +
Sbjct: 302 GSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESR 361
Query: 264 YDTRSEASDSGSESVSFTDGSVRSGSGTDG 293
+D S S+ E V +G+ +S + T+G
Sbjct: 362 FDRDSGESEEAEEEVG--EGTPQSSALTEG 389
Score = 70.1 bits (170), Expect = 7e-12
Identities = 70/323 (21%), Positives = 131/323 (40%), Gaps = 37/323 (11%)
Query: 17 DDILTEVPEQDDEL-YNPESEQDKNEKKGSKRKSDRMESTDTK-RQKPSVHSRQLVSKPL 74
+D + + E+DD L P + + EK ++ R E + ++K H R+
Sbjct: 70 EDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERR------ 123
Query: 75 SSSVSNNKRIVSTKGKSATEYKNE-------EYQRSERNKR---LDADRKIRLSSSASRE 124
KR + K+ E++ + E+ R ER L DR +L RE
Sbjct: 124 -------KRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERE 176
Query: 125 PYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHE 184
+ +K +++ ERRA+ + R + R R S K + + H
Sbjct: 177 RKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKAS-------HW 229
Query: 185 TGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEE----E 240
+ S + + + V+E+ E+ ++ D ++ + + E E E
Sbjct: 230 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 289
Query: 241 EEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKE 300
EEEEEEEEE E+ ++ E + + E ++GS S ++ S S + S+++++E
Sbjct: 290 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 349
Query: 301 RKRARGISP-IVFDRSGSSASES 322
+ + P FDR + E+
Sbjct: 350 NENHLLVVPESRFDRDSGESEEA 372
Score = 46.6 bits (109), Expect = 8e-05
Identities = 69/350 (19%), Positives = 133/350 (38%), Gaps = 58/350 (16%)
Query: 7 EEKDG-ELNVLDDILTEVP-----EQDDELYNPESEQDKNEKKGSKRKSDR----MEST- 55
+EKD ++ LD+IL E E+ E+ ++ D++ K+ S + + ME T
Sbjct: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITI 62
Query: 56 --DTKRQKPSVHSR-----QLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKR 108
R++ S+ R L KP +S +++ K + E K+ + ER
Sbjct: 63 RNSPYRREDSMEDRGEEDDSLAIKP-PQQMSRKEKVHHRKDEKRKEKKHARVKEKEREH- 120
Query: 109 LDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQ 168
+ ++ R +R ++ Q + R+ R G++ + L DR +
Sbjct: 121 -ERRKRHREEQDKARREWERQKRREMAREHSRRER-------GNDGVCLFRDRLEQLERK 172
Query: 169 SSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDED 228
+E E+ E + E EE +E E E + + ED
Sbjct: 173 RERERKMREQQKEQREQ-------------KERERRAEERRKEREARREVSAHHRTMRED 219
Query: 229 GEEEEEEEEEEEEEEEEEEEEYEQDE------RDQKEEGNDYDTRSEASDSGSESVSFTD 282
++ + E +E + ++ EE + + SDS ++ S
Sbjct: 220 YSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAES 279
Query: 283 GSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYAGSEKKHEK 332
S SGSG++ +E+++E + GS++ ES E++ E+
Sbjct: 280 SSAESGSGSEEEEEEEEEE-----------EEEGSTSEESEEEEEEEEEE 318
Score = 40.0 bits (92), Expect = 0.008
Identities = 39/209 (18%), Positives = 88/209 (42%), Gaps = 18/209 (8%)
Query: 159 VDRRASRSSQSSKEEV----NSEEYGSDHETGSSGSSDEQ------GNNTENEEEGVEED 208
+ + R Q K E+ NS++ S ++ G + N+ E+ +E+
Sbjct: 17 LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDR 76
Query: 209 VEEDEEV----EEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDY 264
EED+ + + E+V +E+ +E++ +E+E E E + R+++++
Sbjct: 77 GEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARRE 136
Query: 265 DTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYA 324
R + + E G+ D ++ +++R+R R + ++ E A
Sbjct: 137 WERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERERKMREQQKEQREQKERERRA 196
Query: 325 GSEKK----HEKLSSSVRAVRKDQTSKLK 349
+K ++S+ R +R+D + K+K
Sbjct: 197 EERRKEREARREVSAHHRTMREDYSDKVK 225
Score = 35.4 bits (80), Expect = 0.19
Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 674 RRSRPRERDRERERDRPRDNRRDRERDRG-RDRERERERLCDRDRDRGERG 723
R+ + R +E+ER+ R R E+D+ R+ ER++ R R+ R ERG
Sbjct: 105 RKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERG 155
Score = 33.1 bits (74), Expect = 0.94
Identities = 29/109 (26%), Positives = 43/109 (39%), Gaps = 9/109 (8%)
Query: 628 PPPQAHPPYSGHHPVPHEARYRDK-RVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERE 686
PP Q HH + + + RV + + + R + RR R++ RE
Sbjct: 87 PPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMA 146
Query: 687 RDRPRDNR--------RDRERDRGRDRERERERLCDRDRDRGERGRYRR 727
R+ R R RDR R RERER+ + R ++ R RR
Sbjct: 147 REHSRRERGNDGVCLFRDRLEQLERKRERERKMREQQKEQREQKERERR 195
Score = 31.6 bits (70), Expect = 2.7
Identities = 47/223 (21%), Positives = 72/223 (32%), Gaps = 45/223 (20%)
Query: 506 KMRHKRRMHSQPRSRGRPSRREPVRDVGRR----------RPEDYDIHNSRKKPRIDYPP 555
+ RH+ R R RRE R+ RR R + R++ R
Sbjct: 123 RKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERERKMREQ 182
Query: 556 EFHQRPGYLKDPRYQEVDRRFSGVRRDV-----FLNGSYNDYVREFHNMGPPPPWQGMPP 610
+ QR ++ R +E R+ RR+V + Y+D V+ H W PP
Sbjct: 183 QKEQREQKERERRAEE-RRKEREARREVSAHHRTMREDYSDKVKASH-------WSRSPP 234
Query: 611 YPGMEQPPHHPYYQHHAPPPQAHPPYSGHHPVPHEARYRDKRVHDYDMRVDDFLRRT--- 667
PP + G PV E + D + D R+T
Sbjct: 235 ----------------RPPRERFELGDGRKPVKEEKMEERDLLSDL-QDISDSERKTSSA 277
Query: 668 --QAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERE 708
+ SG S E + E E + + E + + E E
Sbjct: 278 ESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEE 320
Score = 30.8 bits (68), Expect = 4.6
Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 18/90 (20%)
Query: 644 HEARYRDKRVHDYDMRV-DDFLRRTQAVVSGRRSR---------------PRERDRERE- 686
HE R R + D R + RR A RR R R+R+RER+
Sbjct: 120 HERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERERKM 179
Query: 687 RDRPRDNRRDRERDRGRDRERERERLCDRD 716
R++ ++ R +ER+R R ER +ER R+
Sbjct: 180 REQQKEQREQKERER-RAEERRKEREARRE 208
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 84.0 bits (206), Expect = 5e-16
Identities = 55/154 (35%), Positives = 73/154 (47%), Gaps = 22/154 (14%)
Query: 123 REPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSD 182
R+ QP++ +++ +A S + D E D KEE EEY D
Sbjct: 61 RKTQDKQPQEPAPKRKPFAVKADSSSVD-------ECDDSDGTEDMDEKEEDEGEEYSED 113
Query: 183 HETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEE 242
+ DE G+ E +EEG E+ EE EE +ED +ED E ED EEEEEEEEEEEEE
Sbjct: 114 N--------DEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEE 165
Query: 243 EEEEEEEYE-------QDERDQKEEGNDYDTRSE 269
EE E+ + QD ++YD E
Sbjct: 166 EENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDE 199
Score = 64.3 bits (155), Expect = 4e-10
Identities = 34/112 (30%), Positives = 60/112 (53%), Gaps = 8/112 (7%)
Query: 161 RRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAE 220
+R ++ Q + + + ++ S D+ + +E+ +E E E+ +E +
Sbjct: 60 KRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGD 119
Query: 221 EDEEVDEDGEEEEEEEEEEEEE--------EEEEEEEYEQDERDQKEEGNDY 264
EDEE +E EEEEE EEE+E+ E+EEEEE E++E +++EE D+
Sbjct: 120 EDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDH 171
Score = 60.8 bits (146), Expect = 4e-09
Identities = 36/114 (31%), Positives = 59/114 (51%), Gaps = 2/114 (1%)
Query: 187 SSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEE 246
+ SS ++ ++++ E+ E++ +E EE ED DE DED E+EE + EEEEE EEE+
Sbjct: 82 ADSSSVDECDDSDGTEDMDEKEEDEGEEYSED--NDEPGDEDEEDEEGDREEEEEIEEED 139
Query: 247 EEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKE 300
E++ E E + EE + + E + +E + R T+ D E
Sbjct: 140 EDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDE 193
Score = 44.7 bits (104), Expect = 3e-04
Identities = 20/70 (28%), Positives = 37/70 (52%)
Query: 209 VEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRS 268
V+ D ++ ++ + ++ E+EE+E EE E+ +E +E E+DE +EE + +
Sbjct: 80 VKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEED 139
Query: 269 EASDSGSESV 278
E D E V
Sbjct: 140 EDDDEDGEDV 149
Score = 34.7 bits (78), Expect = 0.32
Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
Query: 221 EDEEVDE-DGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVS 279
+ VDE D + E+ +E+EE+E EE E + D+ EE + D E +
Sbjct: 83 DSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDD 142
Query: 280 FTDGSVRSGSGTDGSDEKKKERK 302
DG + +E+++E +
Sbjct: 143 DEDGEDVEDEEEEEEEEEEEEEE 165
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 83.2 bits (204), Expect = 8e-16
Identities = 77/327 (23%), Positives = 130/327 (39%), Gaps = 22/327 (6%)
Query: 8 EKD---GELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSV 64
EKD GE+ + E+ E+++ EQ++ E++ +K E + ++
Sbjct: 678 EKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGE 737
Query: 65 HSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASRE 124
+ + + +G+ E + EE + + + ++ R E
Sbjct: 738 GEEE---------EGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGE 788
Query: 125 PYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHE 184
+Q E + + E R + +G E G EV+ + +E EE G E
Sbjct: 789 EEGDQGEG---EEEETEGRGEEKE-EGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEE 844
Query: 185 TGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEE 244
G +E+ + EEEG E + EE+ E E E+EE + +GEEE E E EEEE E
Sbjct: 845 --EEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEG 902
Query: 245 EEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRA 304
E EEE E + +++ EG + E G E +G G G + E + E +
Sbjct: 903 EGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEG 962
Query: 305 RGISPIVFDRSGSSASESYAGSEKKHE 331
G + G E G ++ E
Sbjct: 963 EGEG----EEEGEGEGEEGEGEGEEEE 985
Score = 74.3 bits (181), Expect = 4e-13
Identities = 76/335 (22%), Positives = 123/335 (36%), Gaps = 31/335 (9%)
Query: 4 DSREEKDGELNVLDDILTEVPEQDDELYNPESEQD-----KNEKKGSKRKSDRMESTDTK 58
+ +E+K+ E + E+ E +E + E++ + EK+G ++ E + +
Sbjct: 708 EEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGE 767
Query: 59 RQKPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLS 118
R+K ++ GK E EE + E + R
Sbjct: 768 REKEE----------------GERKKEERAGKE--EKGEEEGDQGEGEEEETEGRGEEKE 809
Query: 119 SSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEE 178
E + + K + + E + +G E G + + EE EE
Sbjct: 810 EGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEE 869
Query: 179 YGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEE 238
G + E E E E EG EE+ E + E E + E +EE E EEE EE E
Sbjct: 870 EGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGE 929
Query: 239 EEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSG--TDGSDE 296
E EEEE E E E E + +EE +++ E + E +G G G +G E
Sbjct: 930 GEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGE 989
Query: 297 KKKERKRARGISPIVFDRSGSSASESYAGSEKKHE 331
++E G + G E E++ E
Sbjct: 990 GEEEEGEEEG------EEEGEGEEEGEGEGEEEEE 1018
Score = 73.9 bits (180), Expect = 5e-13
Identities = 71/309 (22%), Positives = 130/309 (42%), Gaps = 38/309 (12%)
Query: 27 DDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHS-RQLVSKPLSSSVSNNKRIV 85
D+E+ PE ++ + KG+ + +E+ + + VH R+ ++ LS +++ +
Sbjct: 581 DEEVEIPEEKEGAEDSKGNGIEEQEVEANE---ENVKVHGGRKEKTEILSDDLTDKAEVS 637
Query: 86 STKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAK 145
K KS E ++ R D SS + + EK ++D R
Sbjct: 638 EGKAKSVGEAEDGPEGRG--------DGTCEEGSSGAEHWQDEEREKG---EKDKGRGEM 686
Query: 146 SPTPDGSERIGLEVD---RRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEE 202
+G + + + + R Q +E+ + +E + E G +E G E E
Sbjct: 687 ERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEME---EGGEEEHGEGEEEEG 743
Query: 203 EGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGN 262
+ EE+ +E E EE E+ E + + EE E ++EE +EE+ EEE +Q E +++E
Sbjct: 744 DREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEET-- 801
Query: 263 DYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASES 322
+ R E + G G V G +G E+++E + G + G E
Sbjct: 802 --EGRGEEKEEG--------GEVEGGEVEEGKGEREEEEEEGEG-----EEEEGEGEEEE 846
Query: 323 YAGSEKKHE 331
G E++ E
Sbjct: 847 GEGEEEEGE 855
Score = 73.9 bits (180), Expect = 5e-13
Identities = 60/195 (30%), Positives = 81/195 (41%), Gaps = 15/195 (7%)
Query: 150 DGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHE-TGSSGSSDEQGNNTENEEEGVEED 208
+G E G + EE E G D E G + +G E E EG EE
Sbjct: 911 EGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEG 970
Query: 209 VEEDEEVEEDAEEDEEV----DEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDY 264
E EE E + EE+E +E+GEEE EEE E EEE E E EE E+ E + + EG
Sbjct: 971 EGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEG--- 1027
Query: 265 DTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYA 324
E G E +G R G + + +E + + +G +E
Sbjct: 1028 ---EEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGK---YQETGEEENERQD 1081
Query: 325 GSE-KKHEKLSSSVR 338
G E KK K+ SV+
Sbjct: 1082 GEEYKKVSKIKGSVK 1096
Score = 72.0 bits (175), Expect = 2e-12
Identities = 72/321 (22%), Positives = 119/321 (37%), Gaps = 19/321 (5%)
Query: 22 EVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNN 81
E EQ + + E+++ ++G + + E + R++ +
Sbjct: 708 EEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGE------GKEEGEG 761
Query: 82 KRIVSTKGKSATEYKNEEYQRSERNKRLDADR----KIRLSSSASREPYKNQPEKTCVRK 137
+ + + K E K EE E + D+ + + + E V +
Sbjct: 762 EEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEE 821
Query: 138 RDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDE-QGN 196
ER + +G E G + + + E EE G + E G E +G
Sbjct: 822 GKGEREEEEEEGEGEEEEGEGEEEEGE--GEEEEGEGKGEEEGEEGEGEEEGEEGEGEGE 879
Query: 197 NTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEE------EEEEEEEEEEEEEEEEY 250
E E EG EE E EE E + E +EE + +GEEEE EE EE E E EEEE E
Sbjct: 880 EEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEG 939
Query: 251 EQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGISPI 310
E ++ + + E + + E + E +G G G +E + E + G
Sbjct: 940 EGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEG 999
Query: 311 VFDRSGSSASESYAGSEKKHE 331
+ G E E++ E
Sbjct: 1000 EEEGEGEEEGEGEGEEEEEGE 1020
Score = 66.2 bits (160), Expect = 1e-10
Identities = 46/183 (25%), Positives = 86/183 (46%), Gaps = 10/183 (5%)
Query: 150 DGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDV 209
+G E G + + + E EE G E G +E+ E E EG E +
Sbjct: 973 EGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEG 1032
Query: 210 EEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYD--TR 267
E +EE E+ E+ E + +GEE EEEEEEE + +E E E +++++G +Y ++
Sbjct: 1033 EGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGE--EENERQDGEEYKKVSK 1090
Query: 268 SEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYAGSE 327
+ S + ++ SV + G +G +++ K +++ + ++G S S+ + +
Sbjct: 1091 IKGSVKYGKHKTYQKKSVTNTQG-NGKEQRSKMPVQSKRLL-----KNGPSGSKKFWNNV 1144
Query: 328 KKH 330
H
Sbjct: 1145 LPH 1147
Score = 37.0 bits (84), Expect = 0.065
Identities = 62/262 (23%), Positives = 101/262 (38%), Gaps = 49/262 (18%)
Query: 84 IVSTKGKSATEYKNEEYQR-SERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPER 142
I T G SA N + R SERN L S E QPE+ + +
Sbjct: 431 IEGTLGLSACFLPNSVFPRCSERN----------LQESVLSEQDLMQPEEPDYLLDEMTK 480
Query: 143 RAKSPTPDGSERIGLEVD---RRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTE 199
A+ E +G D S S+++ + + + G + TE
Sbjct: 481 EAEIDNSSTVESLGETTDILNMTHIMSLNSNEKSLKLSPVQKQKKQQTIGELTQDTALTE 540
Query: 200 NEEEGVEEDVEEDEEVEE------------------DAEEDEEVDEDGEEEEEEEE---- 237
N++ E++ E +E + +A DEEV+ E+E E+
Sbjct: 541 NDDSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEVEIPEEKEGAEDSKGNG 600
Query: 238 -EEEEEEEEEEEEYEQDERDQKEE--GNDYDTRSEASDSGSESV-SFTDGSVRSGSGT-- 291
EE+E E EE R +K E +D ++E S+ ++SV DG G GT
Sbjct: 601 IEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCE 660
Query: 292 DGS-------DEKKKERKRARG 306
+GS DE++++ ++ +G
Sbjct: 661 EGSSGAEHWQDEEREKGEKDKG 682
>gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Homo
sapiens]
Length = 1108
Score = 79.0 bits (193), Expect = 1e-14
Identities = 51/117 (43%), Positives = 67/117 (57%), Gaps = 3/117 (2%)
Query: 158 EVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVE-EDVEEDEEVE 216
E + R S + + E+ S E+ + S G SDE+ + T E+E E E+ EED+E+E
Sbjct: 973 EAEERDSTEQEEAGPEILSNEHVGARASPSQGDSDERESLTREEDEDSEKEEEEEDKEME 1032
Query: 217 EDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDS 273
E EE E G+EEEEEEEEE EEEE EE E E +E K EG D R+E+ S
Sbjct: 1033 ELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEE--AKTEGLMKDDRAESQAS 1087
Score = 49.7 bits (117), Expect = 1e-05
Identities = 46/163 (28%), Positives = 71/163 (43%), Gaps = 14/163 (8%)
Query: 116 RLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVN 175
R S S S + N C KR+ E R + + I L + +R+S S +
Sbjct: 952 RFSHSGSYSQHMNHRYSYC--KREAEERDSTEQEEAGPEI-LSNEHVGARASPSQGDSDE 1008
Query: 176 SEEYGSDHETGSSGSSDEQGNNTEN--EEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEE 233
E + + S +E+ E EE+ E+ ++EE EE+ EEV EEE
Sbjct: 1009 RESLTREEDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEE----EEV-----EEE 1059
Query: 234 EEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSE 276
E EE E E EE + E +D+R + + + E+S+ SE
Sbjct: 1060 EVEEAENEGEEAKTEGLMKDDRAESQASSLGQKVGESSEQVSE 1102
Score = 32.3 bits (72), Expect = 1.6
Identities = 28/132 (21%), Positives = 51/132 (38%)
Query: 150 DGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDV 209
D + L + S + + E V ++ +D SS+ +GN E+ ++
Sbjct: 15 DSDDEDKLHIVEEESVTDAADCEGVPEDDLPTDQTVLPGRSSEREGNAKNCWEDDTGKEG 74
Query: 210 EEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSE 269
+E E A+E +D E E + E E+ + EE +QD E + D R
Sbjct: 75 QEILGPEAQADEAGCTVKDDECESDAENEQNHDPNVEEFLQQQDTAVIFPEAPEEDQRQG 134
Query: 270 ASDSGSESVSFT 281
++ + T
Sbjct: 135 TPEASGHDENGT 146
Score = 30.8 bits (68), Expect = 4.6
Identities = 40/194 (20%), Positives = 72/194 (37%), Gaps = 57/194 (29%)
Query: 46 KRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSER 105
KR+++ +ST+ + P + S + V S S + S + +S T ++E+ ++ E
Sbjct: 971 KREAEERDSTEQEEAGPEILSNEHVGARASPSQGD-----SDERESLTREEDEDSEKEEE 1025
Query: 106 NKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASR 165
+ +E + Q EK C + P G E
Sbjct: 1026 EE--------------DKEMEELQEEKECEK------------PQGDE------------ 1047
Query: 166 SSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEV 225
+ +EEV EE E+ N E EE E +++D + + ++V
Sbjct: 1048 EEEEEEEEVEEEEV-------------EEAEN-EGEEAKTEGLMKDDRAESQASSLGQKV 1093
Query: 226 DEDGEEEEEEEEEE 239
E E+ EE+ E
Sbjct: 1094 GESSEQVSEEKTNE 1107
>gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Homo
sapiens]
Length = 1124
Score = 79.0 bits (193), Expect = 1e-14
Identities = 51/117 (43%), Positives = 67/117 (57%), Gaps = 3/117 (2%)
Query: 158 EVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVE-EDVEEDEEVE 216
E + R S + + E+ S E+ + S G SDE+ + T E+E E E+ EED+E+E
Sbjct: 989 EAEERDSTEQEEAGPEILSNEHVGARASPSQGDSDERESLTREEDEDSEKEEEEEDKEME 1048
Query: 217 EDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDS 273
E EE E G+EEEEEEEEE EEEE EE E E +E K EG D R+E+ S
Sbjct: 1049 ELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEE--AKTEGLMKDDRAESQAS 1103
Score = 49.7 bits (117), Expect = 1e-05
Identities = 46/163 (28%), Positives = 71/163 (43%), Gaps = 14/163 (8%)
Query: 116 RLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVN 175
R S S S + N C KR+ E R + + I L + +R+S S +
Sbjct: 968 RFSHSGSYSQHMNHRYSYC--KREAEERDSTEQEEAGPEI-LSNEHVGARASPSQGDSDE 1024
Query: 176 SEEYGSDHETGSSGSSDEQGNNTEN--EEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEE 233
E + + S +E+ E EE+ E+ ++EE EE+ EEV EEE
Sbjct: 1025 RESLTREEDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEE----EEV-----EEE 1075
Query: 234 EEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSE 276
E EE E E EE + E +D+R + + + E+S+ SE
Sbjct: 1076 EVEEAENEGEEAKTEGLMKDDRAESQASSLGQKVGESSEQVSE 1118
Score = 31.6 bits (70), Expect = 2.7
Identities = 30/135 (22%), Positives = 54/135 (40%), Gaps = 7/135 (5%)
Query: 150 DGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDV 209
D + L + S + + E V ++ +D SS+ +GN + E+D
Sbjct: 32 DSDDEDKLHIVEEESVTDAADCEGVPEDDLPTDQTVLPGRSSEREGN----AKNCWEDDR 87
Query: 210 EEDEEV---EEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDT 266
+E +E+ E A+E +D E E + E E+ + EE +QD E + D
Sbjct: 88 KEGQEILGPEAQADEAGCTVKDDECESDAENEQNHDPNVEEFLQQQDTAVIFPEAPEEDQ 147
Query: 267 RSEASDSGSESVSFT 281
R ++ + T
Sbjct: 148 RQGTPEASGHDENGT 162
Score = 30.8 bits (68), Expect = 4.6
Identities = 40/194 (20%), Positives = 72/194 (37%), Gaps = 57/194 (29%)
Query: 46 KRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSER 105
KR+++ +ST+ + P + S + V S S + S + +S T ++E+ ++ E
Sbjct: 987 KREAEERDSTEQEEAGPEILSNEHVGARASPSQGD-----SDERESLTREEDEDSEKEEE 1041
Query: 106 NKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASR 165
+ +E + Q EK C + P G E
Sbjct: 1042 EE--------------DKEMEELQEEKECEK------------PQGDE------------ 1063
Query: 166 SSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEV 225
+ +EEV EE E+ N E EE E +++D + + ++V
Sbjct: 1064 EEEEEEEEVEEEEV-------------EEAEN-EGEEAKTEGLMKDDRAESQASSLGQKV 1109
Query: 226 DEDGEEEEEEEEEE 239
E E+ EE+ E
Sbjct: 1110 GESSEQVSEEKTNE 1123
Score = 30.0 bits (66), Expect = 7.9
Identities = 27/123 (21%), Positives = 53/123 (43%), Gaps = 8/123 (6%)
Query: 162 RASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEE 221
R R Q++ N Y + ET S SD++ EEE V + + + E+D
Sbjct: 6 RCKRRKQANPRRNNVTNYNTVVETNSD--SDDEDKLHIVEEESVTDAADCEGVPEDDLPT 63
Query: 222 DEEV------DEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGS 275
D+ V + +G + E++ +E +E E + DE + ++ ++ +E +
Sbjct: 64 DQTVLPGRSSEREGNAKNCWEDDRKEGQEILGPEAQADEAGCTVKDDECESDAENEQNHD 123
Query: 276 ESV 278
+V
Sbjct: 124 PNV 126
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 78.2 bits (191), Expect = 3e-14
Identities = 52/131 (39%), Positives = 71/131 (54%), Gaps = 13/131 (9%)
Query: 149 PDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEED 208
P+ +E + R+ S E+ SEE SS ++G + EE+ EE+
Sbjct: 218 PEDAEEVVEVTTERSQDLCPQSLEDAASEE-----------SSKQKGILSHEEED--EEE 264
Query: 209 VEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRS 268
EE+EE EED EE+EE +E+ EEEEEEEEEEEEEEEEEEEE + +E+ + +
Sbjct: 265 EEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQK 324
Query: 269 EASDSGSESVS 279
G ES S
Sbjct: 325 APELRGPESPS 335
Score = 69.3 bits (168), Expect = 1e-11
Identities = 34/80 (42%), Positives = 50/80 (62%)
Query: 202 EEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEG 261
E+ E+ + + + EEDEE +E+ EEEEE+EEEEEEEEEEEEEE E++E +++EE
Sbjct: 241 EDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE 300
Query: 262 NDYDTRSEASDSGSESVSFT 281
+ + + E S T
Sbjct: 301 EEEEEEAAPDVIFQEDTSHT 320
Score = 65.1 bits (157), Expect = 2e-10
Identities = 40/120 (33%), Positives = 65/120 (54%), Gaps = 19/120 (15%)
Query: 184 ETGSSGSSDEQGNN-----TENEEEGVEEDVEEDEEV----EEDAEEDE----------E 224
+ + G++ E+G E+ EE VE E +++ EDA +E E
Sbjct: 199 QEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHE 258
Query: 225 VDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGS 284
+++ EEEEEEEEEE+EEEEEEEEE E++E +++EE + + E ++ + + D S
Sbjct: 259 EEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTS 318
Score = 59.3 bits (142), Expect = 1e-08
Identities = 75/291 (25%), Positives = 110/291 (37%), Gaps = 33/291 (11%)
Query: 21 TEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSN 80
+E E D + ESE + D + +T + V S S P+ S+ ++
Sbjct: 94 SEDTEVKDASVSDESEGTLEGAEAETSGQDEIHRPETAEGRSPVKSH-FGSNPIGSATAS 152
Query: 81 NKRIVST-KGKSATEYKNEEYQRSERNKRLDADRK-------IRLSSSASREPYKNQPEK 132
+K S+ +G AT N E D + + L A+ + EK
Sbjct: 153 SKGSYSSYQGIIATSLLNLGQIAEETLVEEDLGQAAKPGPGIVHLLQEAAEGAASEEGEK 212
Query: 133 TC-VRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSS 191
++ D E + T + ++ AS S K ++ EE + E
Sbjct: 213 GLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEE------- 265
Query: 192 DEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYE 251
E+ E +EE EE+ EE+EE EE+ EEEEEEEEEEEEEEE +
Sbjct: 266 -EEEEEEEEDEEEEEEEEEEEEEEEEE-----------EEEEEEEEEEEEEEEAAPDVIF 313
Query: 252 QDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERK 302
Q++ + R S S S VRS D DE RK
Sbjct: 314 QEDTSHTSAQKAPELRGPESPSPKPEYSVI-VEVRS---DDDKDEDTHSRK 360
Score = 32.7 bits (73), Expect = 1.2
Identities = 44/166 (26%), Positives = 64/166 (38%), Gaps = 14/166 (8%)
Query: 112 DRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSK 171
D++ R S A R P PE T P +P GS + + R RS QS
Sbjct: 7 DKRARTRSKALRGP----PETTAADLSCP-----TPGCTGSGHVRGKYSRH--RSLQSCP 55
Query: 172 EEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEE 231
+ G++ E S +E GV+ D ED EV++ + DE +G
Sbjct: 56 LAKKRKLEGAEAEHLVSKRKSHPLKLALDEGYGVDSDGSEDTEVKDASVSDE---SEGTL 112
Query: 232 EEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSES 277
E E E ++E E E + G++ + AS GS S
Sbjct: 113 EGAEAETSGQDEIHRPETAEGRSPVKSHFGSNPIGSATASSKGSYS 158
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 77.8 bits (190), Expect = 3e-14
Identities = 67/285 (23%), Positives = 115/285 (40%), Gaps = 29/285 (10%)
Query: 4 DSREEKDGELNVLDDILTE-----VPEQDDELYNPESEQDKNEKKGSKRKSDRM------ 52
D E D E D ++ + E EL P E D + +K K K + +
Sbjct: 191 DDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPV 250
Query: 53 ---------ESTDTKRQKPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRS 103
D + R L+S+ +S +K++ KGK E + E +R
Sbjct: 251 APLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERR 310
Query: 104 ERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPER-RAKSPTPDGSERIGLEVDRR 162
ER + + +R+ R + + EK R+R+ +R R ++ D + DR
Sbjct: 311 ERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRD 370
Query: 163 ASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEED 222
RSS +K+ S E D E E+ E E E E + E + E E + E +
Sbjct: 371 RERSSDRNKDRSRSREKSRDRER-------ERERERERERER-ERERERERERERERERE 422
Query: 223 EEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTR 267
E ++D + + EE+EE+ E + E + + E +E +++ R
Sbjct: 423 REREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIR 467
Score = 64.3 bits (155), Expect = 4e-10
Identities = 63/288 (21%), Positives = 125/288 (43%), Gaps = 44/288 (15%)
Query: 4 DSREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPS 63
+ +EK+ E D + ++ D + E ++D++ ++ S R DR S + R +
Sbjct: 334 EREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRER 393
Query: 64 VHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNK-----RLDADRKIRLS 118
R+ + +R + + E + ++ + E ++ R +RK+R
Sbjct: 394 EREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREK 453
Query: 119 SSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEE 178
+A +E KN + + R+ E+ A+ E +RR + ++ + + E+
Sbjct: 454 EAAYQERLKNWEIRERKKTREYEKEAER-----------EEERRREMAKEAKRLKEFLED 502
Query: 179 YGSDHET-----GSS-----------GSSDEQGNNTENEE----------EGVEEDVEED 212
Y D + GS+ +DE+ E EE EG + E
Sbjct: 503 YDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAEL 562
Query: 213 EEVEEDAEE--DEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQK 258
+ +E++AE ++ ++ E EEEEEE++E+EE+ EE E++E +QK
Sbjct: 563 QRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQK 610
Score = 63.9 bits (154), Expect = 5e-10
Identities = 30/53 (56%), Positives = 38/53 (71%)
Query: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGERGRYRR 727
R R RER+RERER+R R+ R+RER+R R+RERERE+ RDR+ E Y R
Sbjct: 391 REREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYER 443
Score = 63.5 bits (153), Expect = 6e-10
Identities = 31/53 (58%), Positives = 41/53 (77%), Gaps = 1/53 (1%)
Query: 674 RRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGERGRYR 726
RR R RER+RERER++ ++ R+RERDR RDR +ER+R DR+RDR +R R R
Sbjct: 322 RREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDR-DRDRER 373
Score = 63.5 bits (153), Expect = 6e-10
Identities = 30/47 (63%), Positives = 37/47 (78%)
Query: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGE 721
R R RER+RERER+R R+ R+RER+R R+RERERER D+ RDR E
Sbjct: 389 RDREREREREREREREREREREREREREREREREREREKDKKRDREE 435
Score = 62.4 bits (150), Expect = 1e-09
Identities = 27/45 (60%), Positives = 36/45 (80%)
Query: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDR 719
+ + RER+RER+RDR R RDR+RDR RDR+R+RER DR++DR
Sbjct: 337 KEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDR 381
Score = 61.2 bits (147), Expect = 3e-09
Identities = 27/48 (56%), Positives = 39/48 (81%)
Query: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGER 722
RSR + RDRERER+R R+ R+RER+R R+RERERER +R+R++ ++
Sbjct: 383 RSREKSRDREREREREREREREREREREREREREREREREREREKDKK 430
Score = 60.8 bits (146), Expect = 4e-09
Identities = 32/53 (60%), Positives = 40/53 (75%), Gaps = 3/53 (5%)
Query: 674 RRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGERGRYR 726
R R RER+RERER+R ++ R+RER+R RDR+R +ER DRDRDR ER R R
Sbjct: 320 RERREREREREREREREKEKERERERERDRDRDRTKER--DRDRDR-ERDRDR 369
Score = 60.1 bits (144), Expect = 7e-09
Identities = 27/45 (60%), Positives = 37/45 (82%)
Query: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDR 719
RSR RE+ R+RER+R R+ R+RER+R R+RERERER +R+R+R
Sbjct: 381 RSRSREKSRDRERERERERERERERERERERERERERERERERER 425
Score = 59.7 bits (143), Expect = 9e-09
Identities = 31/52 (59%), Positives = 36/52 (69%), Gaps = 1/52 (1%)
Query: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGERGRYR 726
R R RERDR+R+R + RD RDRERDR RDRER +R DR R R E+ R R
Sbjct: 341 RERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSR-EKSRDR 391
Score = 58.2 bits (139), Expect = 3e-08
Identities = 29/53 (54%), Positives = 38/53 (71%), Gaps = 1/53 (1%)
Query: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRG-ERGRYR 726
R R +E++RERER+R RD R +ERDR RDRER+R+R +R DR +R R R
Sbjct: 333 REREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSR 385
Score = 58.2 bits (139), Expect = 3e-08
Identities = 30/52 (57%), Positives = 37/52 (71%), Gaps = 1/52 (1%)
Query: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGERGRYR 726
R R R+RDRER DR +D R RE+ R R+RERERER +R+R+R ER R R
Sbjct: 363 RERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERER-ERERER 413
Score = 57.4 bits (137), Expect = 5e-08
Identities = 28/52 (53%), Positives = 37/52 (71%), Gaps = 1/52 (1%)
Query: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGERGRYR 726
R R +ERDR+R+R+R RD R+R DR +DR R RE+ DR+R+R ER R R
Sbjct: 351 RDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERER-ERERER 401
Score = 57.0 bits (136), Expect = 6e-08
Identities = 34/68 (50%), Positives = 40/68 (58%), Gaps = 17/68 (25%)
Query: 675 RSRPRERDRERERDRPRDNRRDRERDR----------------GRDRERERERLCDRDRD 718
R R R+RDR +ERDR RD RDR+RDR RDRERERER +R+R+
Sbjct: 345 RERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERE 404
Query: 719 RGERGRYR 726
R ER R R
Sbjct: 405 R-ERERER 411
Score = 52.0 bits (123), Expect = 2e-06
Identities = 35/69 (50%), Positives = 41/69 (59%), Gaps = 14/69 (20%)
Query: 665 RRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDR------ERERERLCDRDRD 718
+ Q + RR R RER+RERER R+RER+R R+R ERERER DRDRD
Sbjct: 300 KERQEIEKERRERERERERERER-------REREREREREREREKEKERERERERDRDRD 352
Query: 719 R-GERGRYR 726
R ER R R
Sbjct: 353 RTKERDRDR 361
Score = 48.1 bits (113), Expect = 3e-05
Identities = 39/139 (28%), Positives = 59/139 (42%), Gaps = 6/139 (4%)
Query: 168 QSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDE 227
+ K ++ S E +T +E+ E E + +E++ E E E E E +
Sbjct: 270 EEDKRDLISREISKFRDTHKK--LEEEKGKKEKERQEIEKERRERERERE--RERERRER 325
Query: 228 DGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYD-TRSEASDSGSESVSFTDGSVR 286
+ E E E E E+E+E E E E ++D KE D D R D S D S
Sbjct: 326 EREREREREREKEKERERERER-DRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRS 384
Query: 287 SGSGTDGSDEKKKERKRAR 305
D E+++ER+R R
Sbjct: 385 REKSRDRERERERERERER 403
Score = 47.8 bits (112), Expect = 4e-05
Identities = 22/48 (45%), Positives = 33/48 (68%)
Query: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGER 722
R R RER+RERER+R R+ R+RER++ + R+RE + +R + ER
Sbjct: 401 REREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLER 448
Score = 42.7 bits (99), Expect = 0.001
Identities = 21/52 (40%), Positives = 31/52 (59%)
Query: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGERGRYR 726
R R RER+RERER+R +D +RDRE D ER + R+++ + R +
Sbjct: 411 REREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLK 462
Score = 42.0 bits (97), Expect = 0.002
Identities = 22/54 (40%), Positives = 36/54 (66%), Gaps = 4/54 (7%)
Query: 673 GRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGERGRYR 726
G++ + R+ + R+R R+ R+RER R+RERERER +R++++ ER R R
Sbjct: 296 GKKEKERQEIEKERRERERERERERER---REREREREREREREKEK-ERERER 345
Score = 41.2 bits (95), Expect = 0.003
Identities = 68/303 (22%), Positives = 111/303 (36%), Gaps = 44/303 (14%)
Query: 67 RQLVSKPLSSSVSNNKRIVSTKGKSAT----EYKNEEYQRSERNKRLDADRKIRLSSSAS 122
RQL++K V + KR+ GK EYK E + R RL D +I
Sbjct: 104 RQLLAK--CGLVLSWKRVQGASGKLQAFGFCEYKEPE--STLRALRLLHDLQIGEKKLLV 159
Query: 123 REPYKNQPE----KTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEE 178
+ K + + K + + R ++ T D E + E RR + EV E
Sbjct: 160 KVDAKTKAQLDEWKAKKKASNGNARPETVTNDDEEALDEETKRRDQMIKGAI--EVLIRE 217
Query: 179 YGSDHETGSSGSSDEQGNNTENEEEGV----------------EEDVEEDEEVEE----- 217
Y S+ S S + ++E + +ED+ E E+
Sbjct: 218 YSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLI 277
Query: 218 --------DAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSE 269
D + E ++ +E+E +E E+E E E E E E++ R+++ E R +
Sbjct: 278 SREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREK 337
Query: 270 ASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYAGSEKK 329
+ E D D E+ ++R R R S DRS S E++
Sbjct: 338 EKERERERERDRDRDRTKERDRDRDRERDRDRDRERS-SDRNKDRSRSREKSRDRERERE 396
Query: 330 HEK 332
E+
Sbjct: 397 RER 399
Score = 36.2 bits (82), Expect = 0.11
Identities = 20/59 (33%), Positives = 33/59 (55%), Gaps = 1/59 (1%)
Query: 662 DFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERE-RERLCDRDRDR 719
D + R + + E ++E++R + RER+R R+RERE RER +R+R+R
Sbjct: 275 DLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERERERER 333
Score = 33.5 bits (75), Expect = 0.72
Identities = 20/50 (40%), Positives = 30/50 (60%), Gaps = 5/50 (10%)
Query: 677 RPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGERGRYR 726
R + E E+ + R++ E++R R+RERERE R+R+R ER R R
Sbjct: 285 RDTHKKLEEEKGKKEKERQEIEKER-RERERERE----RERERRERERER 329
Score = 30.8 bits (68), Expect = 4.6
Identities = 20/83 (24%), Positives = 41/83 (49%), Gaps = 9/83 (10%)
Query: 644 HEARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGR 703
+E R ++++ + + + L+ + R R + R+ E+E +R +R R+ +
Sbjct: 441 YERRKLERKLREKEAAYQERLKNWEI-----RERKKTREYEKEAER----EEERRREMAK 491
Query: 704 DRERERERLCDRDRDRGERGRYR 726
+ +R +E L D D DR + YR
Sbjct: 492 EAKRLKEFLEDYDDDRDDPKYYR 514
Score = 30.8 bits (68), Expect = 4.6
Identities = 21/70 (30%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Query: 651 KRVHDYDMRVD-DFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERER 709
K+ +Y+ + + RR + +R + D + +RD P+ R + R RDRE+E
Sbjct: 470 KKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEM 529
Query: 710 ERLCDRDRDR 719
E +RDR R
Sbjct: 530 E-ADERDRKR 538
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 77.8 bits (190), Expect = 3e-14
Identities = 42/93 (45%), Positives = 56/93 (60%)
Query: 197 NTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERD 256
N+ +EEE EE+ EE+EE EE+ EED E +E+ EEE EEEEEEEEE EEE E E+ E +
Sbjct: 884 NSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELE 943
Query: 257 QKEEGNDYDTRSEASDSGSESVSFTDGSVRSGS 289
++EE D + E + G V G+
Sbjct: 944 EEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGA 976
Score = 77.0 bits (188), Expect = 6e-14
Identities = 42/87 (48%), Positives = 57/87 (65%)
Query: 190 SSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEE 249
SSDE+ E EEE EE+ EE+E+ EE+ E++EE E+ EEEEEE EEE EEEE E EE
Sbjct: 885 SSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEE 944
Query: 250 YEQDERDQKEEGNDYDTRSEASDSGSE 276
E++E +++EE + E +G E
Sbjct: 945 EEEEEDEEEEEELEEVEDLEFGTAGGE 971
Score = 75.1 bits (183), Expect = 2e-13
Identities = 48/122 (39%), Positives = 62/122 (50%), Gaps = 12/122 (9%)
Query: 140 PERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTE 199
P + TP G LE D + S +EE EE +E+ E
Sbjct: 857 PPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEE------------EEEEEEEEE 904
Query: 200 NEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKE 259
EEE EE+ E++EE E+ EE+EE E+ EEEE E EEEEEEE+EEEE E +E + E
Sbjct: 905 EEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLE 964
Query: 260 EG 261
G
Sbjct: 965 FG 966
Score = 62.8 bits (151), Expect = 1e-09
Identities = 34/80 (42%), Positives = 49/80 (61%), Gaps = 4/80 (5%)
Query: 201 EEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEE----EEEEEEYEQDERD 256
EE+ ++ +E EE+ EE+EE +E+ EEEEE+ EEEEE+E EEEEEE E+ E +
Sbjct: 875 EEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEE 934
Query: 257 QKEEGNDYDTRSEASDSGSE 276
+EE + + E D E
Sbjct: 935 FEEEEGELEEEEEEEDEEEE 954
Score = 60.1 bits (144), Expect = 7e-09
Identities = 36/113 (31%), Positives = 56/113 (49%), Gaps = 12/113 (10%)
Query: 209 VEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRS 268
+EED V DEE +E+ EEEEEEEEEEEEEE+ EEEE +++E ++EE + +
Sbjct: 874 LEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEE 933
Query: 269 EASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASE 321
E + E + +E ++E + + + F +G E
Sbjct: 934 EFEEEEGELEE------------EEEEEDEEEEEELEEVEDLEFGTAGGEVEE 974
Score = 35.4 bits (80), Expect = 0.19
Identities = 46/237 (19%), Positives = 84/237 (35%), Gaps = 24/237 (10%)
Query: 22 EVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNN 81
E E+++E E E+++ E+ + + D E + + ++ + +
Sbjct: 888 EEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEE--------- 938
Query: 82 KRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPE 141
+G+ E EE + E + L+ + ++ P T P
Sbjct: 939 ------EGELEEE---EEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPP 989
Query: 142 RRAKS--PTPDGSERIGLEVDRRASRSSQSSKEE--VNSEEYGSDHETGSSGSSDEQGNN 197
P P+ + LEV+ + + + + E S E G S G
Sbjct: 990 ESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPP 1049
Query: 198 TENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDE 254
+ E EE +EE+ E+ + + E EEE E E E E +E EQD+
Sbjct: 1050 PQELVE--EEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDD 1104
Score = 31.2 bits (69), Expect = 3.6
Identities = 29/128 (22%), Positives = 40/128 (31%), Gaps = 12/128 (9%)
Query: 601 PPP-----PWQGMPPYPGMEQPPHHPYYQHHAPPPQAHPPYSGHHPVPHEARYRDKRV-- 653
PPP P PP P E+P P PPP PP PVP ++
Sbjct: 808 PPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPP-----PVPGPVTLPPPQLVP 862
Query: 654 HDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLC 713
V S E + E E + + + E D + E E E
Sbjct: 863 EGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFE 922
Query: 714 DRDRDRGE 721
+ + + E
Sbjct: 923 EEEEEEEE 930
>gi|4504487 histidine rich calcium binding protein precursor [Homo
sapiens]
Length = 699
Score = 77.8 bits (190), Expect = 3e-14
Identities = 62/204 (30%), Positives = 88/204 (43%), Gaps = 20/204 (9%)
Query: 93 TEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGS 152
TE + + R R + D + L A +Q E+T +R + P +
Sbjct: 412 TEVPHHHHHRVPREE--DEEVSAELGHQAPSHRQSHQDEETGHGQRGSIKEMSHHPPGHT 469
Query: 153 ERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEED 212
+ DR R S +E+ E+ GS E S E+G + + ++ EED EE
Sbjct: 470 ----VVKDRSHLRKDDSEEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRDQEDEEDEEEG 525
Query: 213 EEVEEDAEEDEEVDEDGEEEEEEEEEEE--------------EEEEEEEEEYEQDERDQK 258
+ + EE+EE D++ EEEEE+EE E EEEEEEEE E+DE
Sbjct: 526 HGLSLNQEEEEEEDKEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEEEGLEEDEPRFT 585
Query: 259 EEGNDYDTRSEASDSGSESVSFTD 282
N D R EA + SE S D
Sbjct: 586 IIPNPLDRREEAGGASSEEESGED 609
Score = 51.2 bits (121), Expect = 3e-06
Identities = 38/131 (29%), Positives = 55/131 (41%), Gaps = 15/131 (11%)
Query: 150 DGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDV 209
D S+ G + S+ + E V+ EE ++H + G +TE+ E
Sbjct: 94 DVSKEYGHLLPGHRSQDHKVGDEGVSGEEVFAEHGGQARGHRGHGSEDTEDSAEHRHHLP 153
Query: 210 EEDEEVEEDAEEDEEVDE--------------DGEEEE-EEEEEEEEEEEEEEEEYEQDE 254
+D +EDE V DGE++E EEEEEEEEEEEE EY
Sbjct: 154 SHRSHSHQDEDEDEVVSSEHHHHILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQA 213
Query: 255 RDQKEEGNDYD 265
+ G++ D
Sbjct: 214 HRHRGHGSEED 224
Score = 47.0 bits (110), Expect = 6e-05
Identities = 34/148 (22%), Positives = 66/148 (44%), Gaps = 26/148 (17%)
Query: 148 TPDGSE-RIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVE 206
T D +E R L R S + E V+SE + H G G + E EEE E
Sbjct: 142 TEDSAEHRHHLPSHRSHSHQDEDEDEVVSSEHH---HHILRHGHRGHDGEDDEGEEEEEE 198
Query: 207 EDVEEDEEVE----------EDAEEDEEVD------------EDGEEEEEEEEEEEEEEE 244
E+ EE+ E +EEDE+V + EE+++++++++++++
Sbjct: 199 EEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQGHEEDDDDDDDDDDDDD 258
Query: 245 EEEEEYEQDERDQKEEGNDYDTRSEASD 272
+++ E + + +G+ + + SD
Sbjct: 259 DDDVSIEYRHQAHRHQGHGIEEDEDVSD 286
Score = 45.1 bits (105), Expect = 2e-04
Identities = 37/165 (22%), Positives = 61/165 (36%), Gaps = 32/165 (19%)
Query: 164 SRSSQSSKEEVNSEEYG--------SDHETGSSGSSDEQ-------------GNNTENEE 202
S + ++E S+EYG DH+ G G S E+ G+ +E+ E
Sbjct: 84 SHPDREKEDEDVSKEYGHLLPGHRSQDHKVGDEGVSGEEVFAEHGGQARGHRGHGSEDTE 143
Query: 203 EGVEE-----------DVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYE 251
+ E +EDE+ +E + G + E++E EEEEEEEEE E
Sbjct: 144 DSAEHRHHLPSHRSHSHQDEDEDEVVSSEHHHHILRHGHRGHDGEDDEGEEEEEEEEEEE 203
Query: 252 QDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDE 296
+ + + + + D G G + D+
Sbjct: 204 EASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQGHEEDDD 248
Score = 41.2 bits (95), Expect = 0.003
Identities = 27/131 (20%), Positives = 56/131 (42%), Gaps = 11/131 (8%)
Query: 158 EVDRRASRSSQSSKEEVNSEEYGSD-HETGSSGSSDEQG-------NNTENEEEGVEEDV 209
E D + +EE S EYG H GS +++ + + +G EED
Sbjct: 188 EDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQGHEEDD 247
Query: 210 EEDEEVEEDAEEDE---EVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDT 266
++D++ ++D ++D+ E + EE+E+ + + R + E +D D
Sbjct: 248 DDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSHRHRSHEEDDNDD 307
Query: 267 RSEASDSGSES 277
+++ G ++
Sbjct: 308 DDVSTEYGHQA 318
Score = 37.0 bits (84), Expect = 0.065
Identities = 48/212 (22%), Positives = 78/212 (36%), Gaps = 29/212 (13%)
Query: 138 RDPERRAKSPTPDGSER--IGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQG 195
RDP R +S D ++ + E +A R KEEV + H QG
Sbjct: 291 RDPSHRHRSHEEDDNDDDDVSTEYGHQAHRHQDHRKEEVEAVSGEHHHHVPDHR---HQG 347
Query: 196 NNTENEEEGVEEDV--------------EEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEE 241
+ E E+E V + EE+EE E + V + +EE+ +
Sbjct: 348 HRDEEEDEDVSTERWHQGPQHVHHGLVDEEEEEEEITVQFGHYVASHQPRGHKSDEEDFQ 407
Query: 242 EEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDG--SVRSGSGTDGSDEKKK 299
+E + E + R +EE + +++ G ++ S +G G GS K
Sbjct: 408 DEYKTEVPHHHHHRVPREEDEEV-----SAELGHQAPSHRQSHQDEETGHGQRGS---IK 459
Query: 300 ERKRARGISPIVFDRSGSSASESYAGSEKKHE 331
E +V DRS +S EK+ +
Sbjct: 460 EMSHHPPGHTVVKDRSHLRKDDSEEEKEKEED 491
Score = 30.8 bits (68), Expect = 4.6
Identities = 22/131 (16%), Positives = 46/131 (35%)
Query: 150 DGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDV 209
D + + +E +A R EE G H S + ++ ++++ E
Sbjct: 257 DDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSHRHRSHEEDDNDDDDVSTEYGH 316
Query: 210 EEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSE 269
+ + EE E V + + + +EEE+E+ + Q + + E
Sbjct: 317 QAHRHQDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDEDVSTERWHQGPQHVHHGLVDE 376
Query: 270 ASDSGSESVSF 280
+ +V F
Sbjct: 377 EEEEEEITVQF 387
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 77.0 bits (188), Expect = 6e-14
Identities = 79/357 (22%), Positives = 151/357 (42%), Gaps = 21/357 (5%)
Query: 10 DGELNVLDDILTEVPEQDDELYNPES---EQDKNEKKGSKRKSDRMESTDTKRQ-KPSVH 65
+ LNV D L V + DDE N ++ +N K K + DTK+ K S
Sbjct: 240 ENSLNV--DFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSD 297
Query: 66 SRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSE----RNKRLDADR-KIRLSSS 120
+ SK K+ V K K+ E +E +++R D + K +L
Sbjct: 298 AESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKD 357
Query: 121 ASREPYKNQPEKTCVRKRDPE--RRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEE 178
++ K PE T D + R S+ + D + S S+ E+ S+E
Sbjct: 358 DKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKE 417
Query: 179 YGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEE 238
D + S + + +N+EE + D E + ++ +++++ +D ++++++++
Sbjct: 418 SQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDA 477
Query: 239 EEEEEEEEEE---EYEQDERDQKE-EGNDYDTRSEA-SDSGSESVSFTDGS---VRSGSG 290
++ E E E E ++D++ KE +G+ D + +A D+ S F + S ++ +
Sbjct: 478 KKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTK 537
Query: 291 TDGSDEKKKERKRARGISPIVFDRSGSSASESYAGSEKKHEKLSSSVRAVRKDQTSK 347
GSD + +E G + + G+SA+ G E K SS + ++ K
Sbjct: 538 IKGSDTESEESLYKPGAKKKIDESDGTSANSKMEGLESKRGFRMSSKKTTFNEKGEK 594
Score = 60.5 bits (145), Expect = 5e-09
Identities = 61/342 (17%), Positives = 142/342 (41%), Gaps = 26/342 (7%)
Query: 32 NPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNKRIVSTKGKS 91
NPES+ K K +K + K +H++ K L S ++N I ++
Sbjct: 182 NPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSEN 241
Query: 92 ATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDG 151
+ ++ ++ D +R S + + Y + K K+D ++ AK +
Sbjct: 242 SLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTK--YTKKDTKKNAKKSSDAE 299
Query: 152 SE--RIGLEVDRRASRS--SQSSKEEVNSEEYGSDHETGSSG-------------SSDEQ 194
SE + + ++ ++ K++V + +D E+G S D++
Sbjct: 300 SEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDK 359
Query: 195 GNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDE 254
+T+ E + + + ++ D+ ++ ++ +++++ ++ + E E E ++ +
Sbjct: 360 KKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQ 419
Query: 255 RDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGISPIVFDR 314
+D+K++ D T ++ S E + D S G G ++KK +K ++ +
Sbjct: 420 KDEKKDKKDSKTDNKKSVKNDEESTDAD-SEPKGDSKKGKKDEKKGKKDSKKDDKKKDAK 478
Query: 315 SGSSASESYAGSEKKHEKLSSSVRAVRKDQTSKLKYVLQDAR 356
+ ++E + E K +K S K++ K + +DAR
Sbjct: 479 KNAESTEMESDLELKKDKKHS------KEKKGSKKDIKKDAR 514
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 74.3 bits (181), Expect = 4e-13
Identities = 82/346 (23%), Positives = 144/346 (41%), Gaps = 32/346 (9%)
Query: 4 DSREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPS 63
D EE++ E + D L S + K++ + +SD + T +
Sbjct: 1068 DEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSL 1127
Query: 64 VHSRQLVSKPLSSSVSN--NKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSA 121
+ R + + PL S K+ KGKS ++ + +L + + +
Sbjct: 1128 LRKRDVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQAC 1187
Query: 122 SREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGS 181
EP + P+ R P+ + T + E + L +R+ Q+ EE E G
Sbjct: 1188 VIEPIVSIPKAG----RKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEA---EEGE 1240
Query: 182 DHETGSS----GSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEE 237
+ + SS S + N+ E E + E +VEE+EE +EE + +E+ +E EE E
Sbjct: 1241 EEDAASSEVPAASPADSSNSPETETK--EPEVEEEEEKPRVSEEQRQSEEEQQELEEPEP 1298
Query: 238 EEEEE---EEEEEEEYEQDERD-------QKEEGNDYDTRSEASDSGSESVSFTDGSVRS 287
EEEE+ E + ++++ D+ D +K+E + TR + + SF D +++
Sbjct: 1299 EEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQK 1358
Query: 288 GSGTDGSDEKKKERKRARGISPIVFDRSGSS-ASESYAGSEKKHEK 332
S EK K+++ S +S SE AGSE HE+
Sbjct: 1359 ------SREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEE 1398
Score = 54.3 bits (129), Expect = 4e-07
Identities = 73/352 (20%), Positives = 137/352 (38%), Gaps = 36/352 (10%)
Query: 6 REEKDGELNVLDDILTEVPEQDDELY-NPESEQDKNEKKGSKRKSDRMESTDTKRQKPSV 64
R+ K +V+ + ++E E DE + + +SE+ + + + E D P
Sbjct: 1024 RKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPRE 1083
Query: 65 HSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASRE 124
+ R+L S+ + S++KR K+++ + E + D ++ S +
Sbjct: 1084 YFRRLSSQDVLRCQSSSKR------------KSKDEEEDEESDDADDTPILKPVSLLRKR 1131
Query: 125 PYKNQP----EKTCVRKRDPERRAKSPTP-DGSERIGLEVDRRASRSSQS-SKEEVNSEE 178
KN P T ++K+ + KS P +R G + + SR S + E
Sbjct: 1132 DVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEP 1191
Query: 179 YGSDHETGSSGSSDEQGNNTENEEE-GVEEDVEEDEEVEEDAEEDEEVDED--------- 228
S + G E E +E+ + E+ +E+EE++ +AEE EE +E+
Sbjct: 1192 IVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPA 1251
Query: 229 -------GEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFT 281
E E +E E EEEEE+ E+ + ++E+ + E + + +
Sbjct: 1252 ASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQN 1311
Query: 282 DGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYAGSEKKHEKL 333
D + KK+ + V + G S A +K EK+
Sbjct: 1312 DDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKI 1363
Score = 50.4 bits (119), Expect = 6e-06
Identities = 70/305 (22%), Positives = 116/305 (38%), Gaps = 51/305 (16%)
Query: 1 MAADSREEKDGELNVLDDILTEVPEQD--DELYNPESEQDKNEKKGSKRKSDRMESTDTK 58
M A++ E ++GE D +EVP D +PE+E + E + +
Sbjct: 1229 MQAEAEEAEEGEEE--DAASSEVPAASPADSSNSPETETKEPE-------------VEEE 1273
Query: 59 RQKPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLS 118
+KP V Q S+ + + + T ++ E + L++ +K L
Sbjct: 1274 EEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELE 1333
Query: 119 SSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEE--VNS 176
+RE K +P G + L+ + + SR KEE ++S
Sbjct: 1334 EQPTREDVKEEP--------------------GVQESFLDANMQKSREKIKDKEETELDS 1373
Query: 177 EEYGSDHETG-----SSGSSDEQGNNTENEEEGVEEDVEED-EEVEEDAEEDEEVDEDGE 230
EE H+T +GS D+ ++ +EE +E EE+ E D E + V +
Sbjct: 1374 EEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQ 1433
Query: 231 EEEEEEEEEEEEEEE------EEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGS 284
EE E E ++ EE + Y Q + D + + SE + S S S
Sbjct: 1434 EESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQS 1493
Query: 285 VRSGS 289
VRS S
Sbjct: 1494 VRSVS 1498
Score = 47.4 bits (111), Expect = 5e-05
Identities = 64/303 (21%), Positives = 120/303 (39%), Gaps = 35/303 (11%)
Query: 7 EEKDGELNVLDDI-------LTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKR 59
EE+D E + DD L + + P++ +KKG + R KR
Sbjct: 1107 EEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKR 1166
Query: 60 --QKPSVH-SRQLVSKPLSSSVSNNKRIVSTK--GKSATEYKNEEYQRSERNKRLDADRK 114
+KP SR+++ P+S+ + IVS G+ ++EE + + L +RK
Sbjct: 1167 PGRKPGFKLSREIM--PVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERK 1224
Query: 115 IRLSSSASREPYKNQPEKTCVRKR-----------DPERRAKSP-TPDGSERIGLEVDRR 162
A E + E+ PE K P + E+ + ++R
Sbjct: 1225 EEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQR 1284
Query: 163 ASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEED 222
S Q EE EE E ++ ++ ++ ++E++G E ++ E E+ ED
Sbjct: 1285 QSEEEQQELEEPEPEE----EEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTRED 1340
Query: 223 EEVDEDGEEEE----EEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESV 278
+ +E G +E ++ E+ +++EE E + +E + + + S+ E
Sbjct: 1341 VK-EEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEED 1399
Query: 279 SFT 281
S T
Sbjct: 1400 SHT 1402
Score = 44.3 bits (103), Expect = 4e-04
Identities = 51/253 (20%), Positives = 93/253 (36%), Gaps = 30/253 (11%)
Query: 22 EVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNN 81
E E +++ PE +++ E + +++ E D + S + P SS S
Sbjct: 1209 ETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEED------AASSEVPAASPADSSNSPE 1262
Query: 82 KRIVSTKGKSATEYKNEEYQRSERNKRLDAD-RKIRLSSSASREPYKNQPEKTCVRKRDP 140
TE K E + E R+ + R+ EP + E
Sbjct: 1263 -----------TETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQN 1311
Query: 141 ERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEE------YGSDHETGSSGSSDEQ 194
+ DG LE ++ Q ++E+V E ++ + D++
Sbjct: 1312 DDHDADDEDDGH----LESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKE 1367
Query: 195 GNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEE--EEEEEEEEYEQ 252
++EEE D E +E+D E D +EE E +EEEE E + E +
Sbjct: 1368 ETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQA 1427
Query: 253 DERDQKEEGNDYD 265
+ +EE ++++
Sbjct: 1428 VQSLTQEESSEHE 1440
Score = 32.3 bits (72), Expect = 1.6
Identities = 18/51 (35%), Positives = 19/51 (37%), Gaps = 14/51 (27%)
Query: 601 PPPPWQGMPPYP--------------GMEQPPHHPYYQHHAPPPQAHPPYS 637
PPPP Q PP P +QP P PPPQ PP S
Sbjct: 1653 PPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPLS 1703
Score = 31.2 bits (69), Expect = 3.6
Identities = 41/186 (22%), Positives = 74/186 (39%), Gaps = 34/186 (18%)
Query: 78 VSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRK 137
+ +N + + + A E +NEE Q ER + +I + S S E K Q + +
Sbjct: 780 IVSNSVVSEEEEEEAEEGENEEPQCQER------ELEISVGKSVSHEN-KEQDSYSVESE 832
Query: 138 RDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNN 197
+ PE A P S R+ SK+ + + ++ + G +
Sbjct: 833 KKPEVMA----PVSSTRL--------------SKQVLPHDSLPANSQPSRRGRWGRKNRK 874
Query: 198 TENEEEGVEEDVEEDEEV---EEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDE 254
T+ E ++D ++ E + E+ E GE+ E +E+ E EE+ EQ
Sbjct: 875 TQ------ERFGDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTESEEQLVASEEQPS 928
Query: 255 RDQKEE 260
+D K +
Sbjct: 929 QDGKPD 934
Score = 31.2 bits (69), Expect = 3.6
Identities = 36/157 (22%), Positives = 53/157 (33%), Gaps = 23/157 (14%)
Query: 235 EEEEEEEEEEEEEEEYEQDER----------DQKEEGNDYDTRSEASDSGSESVSFT--- 281
EEEEEE EE E EE Q+ + +E + Y SE VS T
Sbjct: 788 EEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLS 847
Query: 282 ----------DGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYAGSEKKHE 331
S S G G +K + + S ++ + + S+ E Y +K E
Sbjct: 848 KQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKSE 907
Query: 332 KLSSSVRAVRKDQTSKLKYVLQDARFFLIKSNNHENV 368
+ + + QD + L K E V
Sbjct: 908 ATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGV 944
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 74.3 bits (181), Expect = 4e-13
Identities = 82/346 (23%), Positives = 144/346 (41%), Gaps = 32/346 (9%)
Query: 4 DSREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPS 63
D EE++ E + D L S + K++ + +SD + T +
Sbjct: 1068 DEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSL 1127
Query: 64 VHSRQLVSKPLSSSVSN--NKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSA 121
+ R + + PL S K+ KGKS ++ + +L + + +
Sbjct: 1128 LRKRDVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQAC 1187
Query: 122 SREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGS 181
EP + P+ R P+ + T + E + L +R+ Q+ EE E G
Sbjct: 1188 VIEPIVSIPKAG----RKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEA---EEGE 1240
Query: 182 DHETGSS----GSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEE 237
+ + SS S + N+ E E + E +VEE+EE +EE + +E+ +E EE E
Sbjct: 1241 EEDAASSEVPAASPADSSNSPETETK--EPEVEEEEEKPRVSEEQRQSEEEQQELEEPEP 1298
Query: 238 EEEEE---EEEEEEEYEQDERD-------QKEEGNDYDTRSEASDSGSESVSFTDGSVRS 287
EEEE+ E + ++++ D+ D +K+E + TR + + SF D +++
Sbjct: 1299 EEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQK 1358
Query: 288 GSGTDGSDEKKKERKRARGISPIVFDRSGSS-ASESYAGSEKKHEK 332
S EK K+++ S +S SE AGSE HE+
Sbjct: 1359 ------SREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEE 1398
Score = 54.3 bits (129), Expect = 4e-07
Identities = 73/352 (20%), Positives = 137/352 (38%), Gaps = 36/352 (10%)
Query: 6 REEKDGELNVLDDILTEVPEQDDELY-NPESEQDKNEKKGSKRKSDRMESTDTKRQKPSV 64
R+ K +V+ + ++E E DE + + +SE+ + + + E D P
Sbjct: 1024 RKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPRE 1083
Query: 65 HSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASRE 124
+ R+L S+ + S++KR K+++ + E + D ++ S +
Sbjct: 1084 YFRRLSSQDVLRCQSSSKR------------KSKDEEEDEESDDADDTPILKPVSLLRKR 1131
Query: 125 PYKNQP----EKTCVRKRDPERRAKSPTP-DGSERIGLEVDRRASRSSQS-SKEEVNSEE 178
KN P T ++K+ + KS P +R G + + SR S + E
Sbjct: 1132 DVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEP 1191
Query: 179 YGSDHETGSSGSSDEQGNNTENEEE-GVEEDVEEDEEVEEDAEEDEEVDED--------- 228
S + G E E +E+ + E+ +E+EE++ +AEE EE +E+
Sbjct: 1192 IVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPA 1251
Query: 229 -------GEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFT 281
E E +E E EEEEE+ E+ + ++E+ + E + + +
Sbjct: 1252 ASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQN 1311
Query: 282 DGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYAGSEKKHEKL 333
D + KK+ + V + G S A +K EK+
Sbjct: 1312 DDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKI 1363
Score = 50.4 bits (119), Expect = 6e-06
Identities = 70/305 (22%), Positives = 116/305 (38%), Gaps = 51/305 (16%)
Query: 1 MAADSREEKDGELNVLDDILTEVPEQD--DELYNPESEQDKNEKKGSKRKSDRMESTDTK 58
M A++ E ++GE D +EVP D +PE+E + E + +
Sbjct: 1229 MQAEAEEAEEGEEE--DAASSEVPAASPADSSNSPETETKEPE-------------VEEE 1273
Query: 59 RQKPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLS 118
+KP V Q S+ + + + T ++ E + L++ +K L
Sbjct: 1274 EEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELE 1333
Query: 119 SSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEE--VNS 176
+RE K +P G + L+ + + SR KEE ++S
Sbjct: 1334 EQPTREDVKEEP--------------------GVQESFLDANMQKSREKIKDKEETELDS 1373
Query: 177 EEYGSDHETG-----SSGSSDEQGNNTENEEEGVEEDVEED-EEVEEDAEEDEEVDEDGE 230
EE H+T +GS D+ ++ +EE +E EE+ E D E + V +
Sbjct: 1374 EEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQ 1433
Query: 231 EEEEEEEEEEEEEEE------EEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGS 284
EE E E ++ EE + Y Q + D + + SE + S S S
Sbjct: 1434 EESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQS 1493
Query: 285 VRSGS 289
VRS S
Sbjct: 1494 VRSVS 1498
Score = 47.4 bits (111), Expect = 5e-05
Identities = 64/303 (21%), Positives = 120/303 (39%), Gaps = 35/303 (11%)
Query: 7 EEKDGELNVLDDI-------LTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKR 59
EE+D E + DD L + + P++ +KKG + R KR
Sbjct: 1107 EEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKR 1166
Query: 60 --QKPSVH-SRQLVSKPLSSSVSNNKRIVSTK--GKSATEYKNEEYQRSERNKRLDADRK 114
+KP SR+++ P+S+ + IVS G+ ++EE + + L +RK
Sbjct: 1167 PGRKPGFKLSREIM--PVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERK 1224
Query: 115 IRLSSSASREPYKNQPEKTCVRKR-----------DPERRAKSP-TPDGSERIGLEVDRR 162
A E + E+ PE K P + E+ + ++R
Sbjct: 1225 EEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQR 1284
Query: 163 ASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEED 222
S Q EE EE E ++ ++ ++ ++E++G E ++ E E+ ED
Sbjct: 1285 QSEEEQQELEEPEPEE----EEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTRED 1340
Query: 223 EEVDEDGEEEE----EEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESV 278
+ +E G +E ++ E+ +++EE E + +E + + + S+ E
Sbjct: 1341 VK-EEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEED 1399
Query: 279 SFT 281
S T
Sbjct: 1400 SHT 1402
Score = 44.3 bits (103), Expect = 4e-04
Identities = 51/253 (20%), Positives = 93/253 (36%), Gaps = 30/253 (11%)
Query: 22 EVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNN 81
E E +++ PE +++ E + +++ E D + S + P SS S
Sbjct: 1209 ETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEED------AASSEVPAASPADSSNSPE 1262
Query: 82 KRIVSTKGKSATEYKNEEYQRSERNKRLDAD-RKIRLSSSASREPYKNQPEKTCVRKRDP 140
TE K E + E R+ + R+ EP + E
Sbjct: 1263 -----------TETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQN 1311
Query: 141 ERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEE------YGSDHETGSSGSSDEQ 194
+ DG LE ++ Q ++E+V E ++ + D++
Sbjct: 1312 DDHDADDEDDGH----LESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKE 1367
Query: 195 GNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEE--EEEEEEEEYEQ 252
++EEE D E +E+D E D +EE E +EEEE E + E +
Sbjct: 1368 ETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQA 1427
Query: 253 DERDQKEEGNDYD 265
+ +EE ++++
Sbjct: 1428 VQSLTQEESSEHE 1440
Score = 32.3 bits (72), Expect = 1.6
Identities = 18/51 (35%), Positives = 19/51 (37%), Gaps = 14/51 (27%)
Query: 601 PPPPWQGMPPYP--------------GMEQPPHHPYYQHHAPPPQAHPPYS 637
PPPP Q PP P +QP P PPPQ PP S
Sbjct: 1653 PPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPLS 1703
Score = 31.2 bits (69), Expect = 3.6
Identities = 41/186 (22%), Positives = 74/186 (39%), Gaps = 34/186 (18%)
Query: 78 VSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRK 137
+ +N + + + A E +NEE Q ER + +I + S S E K Q + +
Sbjct: 780 IVSNSVVSEEEEEEAEEGENEEPQCQER------ELEISVGKSVSHEN-KEQDSYSVESE 832
Query: 138 RDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNN 197
+ PE A P S R+ SK+ + + ++ + G +
Sbjct: 833 KKPEVMA----PVSSTRL--------------SKQVLPHDSLPANSQPSRRGRWGRKNRK 874
Query: 198 TENEEEGVEEDVEEDEEV---EEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDE 254
T+ E ++D ++ E + E+ E GE+ E +E+ E EE+ EQ
Sbjct: 875 TQ------ERFGDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTESEEQLVASEEQPS 928
Query: 255 RDQKEE 260
+D K +
Sbjct: 929 QDGKPD 934
Score = 31.2 bits (69), Expect = 3.6
Identities = 36/157 (22%), Positives = 53/157 (33%), Gaps = 23/157 (14%)
Query: 235 EEEEEEEEEEEEEEEYEQDER----------DQKEEGNDYDTRSEASDSGSESVSFT--- 281
EEEEEE EE E EE Q+ + +E + Y SE VS T
Sbjct: 788 EEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLS 847
Query: 282 ----------DGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYAGSEKKHE 331
S S G G +K + + S ++ + + S+ E Y +K E
Sbjct: 848 KQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKSE 907
Query: 332 KLSSSVRAVRKDQTSKLKYVLQDARFFLIKSNNHENV 368
+ + + QD + L K E V
Sbjct: 908 ATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGV 944
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 74.3 bits (181), Expect = 4e-13
Identities = 82/346 (23%), Positives = 144/346 (41%), Gaps = 32/346 (9%)
Query: 4 DSREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPS 63
D EE++ E + D L S + K++ + +SD + T +
Sbjct: 1068 DEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSL 1127
Query: 64 VHSRQLVSKPLSSSVSN--NKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSA 121
+ R + + PL S K+ KGKS ++ + +L + + +
Sbjct: 1128 LRKRDVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQAC 1187
Query: 122 SREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGS 181
EP + P+ R P+ + T + E + L +R+ Q+ EE E G
Sbjct: 1188 VIEPIVSIPKAG----RKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEA---EEGE 1240
Query: 182 DHETGSS----GSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEE 237
+ + SS S + N+ E E + E +VEE+EE +EE + +E+ +E EE E
Sbjct: 1241 EEDAASSEVPAASPADSSNSPETETK--EPEVEEEEEKPRVSEEQRQSEEEQQELEEPEP 1298
Query: 238 EEEEE---EEEEEEEYEQDERD-------QKEEGNDYDTRSEASDSGSESVSFTDGSVRS 287
EEEE+ E + ++++ D+ D +K+E + TR + + SF D +++
Sbjct: 1299 EEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQK 1358
Query: 288 GSGTDGSDEKKKERKRARGISPIVFDRSGSS-ASESYAGSEKKHEK 332
S EK K+++ S +S SE AGSE HE+
Sbjct: 1359 ------SREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEE 1398
Score = 54.3 bits (129), Expect = 4e-07
Identities = 73/352 (20%), Positives = 137/352 (38%), Gaps = 36/352 (10%)
Query: 6 REEKDGELNVLDDILTEVPEQDDELY-NPESEQDKNEKKGSKRKSDRMESTDTKRQKPSV 64
R+ K +V+ + ++E E DE + + +SE+ + + + E D P
Sbjct: 1024 RKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPRE 1083
Query: 65 HSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASRE 124
+ R+L S+ + S++KR K+++ + E + D ++ S +
Sbjct: 1084 YFRRLSSQDVLRCQSSSKR------------KSKDEEEDEESDDADDTPILKPVSLLRKR 1131
Query: 125 PYKNQP----EKTCVRKRDPERRAKSPTP-DGSERIGLEVDRRASRSSQS-SKEEVNSEE 178
KN P T ++K+ + KS P +R G + + SR S + E
Sbjct: 1132 DVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEP 1191
Query: 179 YGSDHETGSSGSSDEQGNNTENEEE-GVEEDVEEDEEVEEDAEEDEEVDED--------- 228
S + G E E +E+ + E+ +E+EE++ +AEE EE +E+
Sbjct: 1192 IVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPA 1251
Query: 229 -------GEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFT 281
E E +E E EEEEE+ E+ + ++E+ + E + + +
Sbjct: 1252 ASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQN 1311
Query: 282 DGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYAGSEKKHEKL 333
D + KK+ + V + G S A +K EK+
Sbjct: 1312 DDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKI 1363
Score = 50.4 bits (119), Expect = 6e-06
Identities = 70/305 (22%), Positives = 116/305 (38%), Gaps = 51/305 (16%)
Query: 1 MAADSREEKDGELNVLDDILTEVPEQD--DELYNPESEQDKNEKKGSKRKSDRMESTDTK 58
M A++ E ++GE D +EVP D +PE+E + E + +
Sbjct: 1229 MQAEAEEAEEGEEE--DAASSEVPAASPADSSNSPETETKEPE-------------VEEE 1273
Query: 59 RQKPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLS 118
+KP V Q S+ + + + T ++ E + L++ +K L
Sbjct: 1274 EEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELE 1333
Query: 119 SSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEE--VNS 176
+RE K +P G + L+ + + SR KEE ++S
Sbjct: 1334 EQPTREDVKEEP--------------------GVQESFLDANMQKSREKIKDKEETELDS 1373
Query: 177 EEYGSDHETG-----SSGSSDEQGNNTENEEEGVEEDVEED-EEVEEDAEEDEEVDEDGE 230
EE H+T +GS D+ ++ +EE +E EE+ E D E + V +
Sbjct: 1374 EEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQ 1433
Query: 231 EEEEEEEEEEEEEEE------EEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGS 284
EE E E ++ EE + Y Q + D + + SE + S S S
Sbjct: 1434 EESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQS 1493
Query: 285 VRSGS 289
VRS S
Sbjct: 1494 VRSVS 1498
Score = 47.4 bits (111), Expect = 5e-05
Identities = 64/303 (21%), Positives = 120/303 (39%), Gaps = 35/303 (11%)
Query: 7 EEKDGELNVLDDI-------LTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKR 59
EE+D E + DD L + + P++ +KKG + R KR
Sbjct: 1107 EEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKR 1166
Query: 60 --QKPSVH-SRQLVSKPLSSSVSNNKRIVSTK--GKSATEYKNEEYQRSERNKRLDADRK 114
+KP SR+++ P+S+ + IVS G+ ++EE + + L +RK
Sbjct: 1167 PGRKPGFKLSREIM--PVSTQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERK 1224
Query: 115 IRLSSSASREPYKNQPEKTCVRKR-----------DPERRAKSP-TPDGSERIGLEVDRR 162
A E + E+ PE K P + E+ + ++R
Sbjct: 1225 EEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQR 1284
Query: 163 ASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEED 222
S Q EE EE E ++ ++ ++ ++E++G E ++ E E+ ED
Sbjct: 1285 QSEEEQQELEEPEPEE----EEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTRED 1340
Query: 223 EEVDEDGEEEE----EEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESV 278
+ +E G +E ++ E+ +++EE E + +E + + + S+ E
Sbjct: 1341 VK-EEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEED 1399
Query: 279 SFT 281
S T
Sbjct: 1400 SHT 1402
Score = 44.3 bits (103), Expect = 4e-04
Identities = 51/253 (20%), Positives = 93/253 (36%), Gaps = 30/253 (11%)
Query: 22 EVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNN 81
E E +++ PE +++ E + +++ E D + S + P SS S
Sbjct: 1209 ETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEED------AASSEVPAASPADSSNSPE 1262
Query: 82 KRIVSTKGKSATEYKNEEYQRSERNKRLDAD-RKIRLSSSASREPYKNQPEKTCVRKRDP 140
TE K E + E R+ + R+ EP + E
Sbjct: 1263 -----------TETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQN 1311
Query: 141 ERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEE------YGSDHETGSSGSSDEQ 194
+ DG LE ++ Q ++E+V E ++ + D++
Sbjct: 1312 DDHDADDEDDGH----LESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKE 1367
Query: 195 GNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEE--EEEEEEEEYEQ 252
++EEE D E +E+D E D +EE E +EEEE E + E +
Sbjct: 1368 ETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQA 1427
Query: 253 DERDQKEEGNDYD 265
+ +EE ++++
Sbjct: 1428 VQSLTQEESSEHE 1440
Score = 32.3 bits (72), Expect = 1.6
Identities = 18/51 (35%), Positives = 19/51 (37%), Gaps = 14/51 (27%)
Query: 601 PPPPWQGMPPYP--------------GMEQPPHHPYYQHHAPPPQAHPPYS 637
PPPP Q PP P +QP P PPPQ PP S
Sbjct: 1653 PPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPLS 1703
Score = 31.2 bits (69), Expect = 3.6
Identities = 41/186 (22%), Positives = 74/186 (39%), Gaps = 34/186 (18%)
Query: 78 VSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRK 137
+ +N + + + A E +NEE Q ER + +I + S S E K Q + +
Sbjct: 780 IVSNSVVSEEEEEEAEEGENEEPQCQER------ELEISVGKSVSHEN-KEQDSYSVESE 832
Query: 138 RDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNN 197
+ PE A P S R+ SK+ + + ++ + G +
Sbjct: 833 KKPEVMA----PVSSTRL--------------SKQVLPHDSLPANSQPSRRGRWGRKNRK 874
Query: 198 TENEEEGVEEDVEEDEEV---EEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDE 254
T+ E ++D ++ E + E+ E GE+ E +E+ E EE+ EQ
Sbjct: 875 TQ------ERFGDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTESEEQLVASEEQPS 928
Query: 255 RDQKEE 260
+D K +
Sbjct: 929 QDGKPD 934
Score = 31.2 bits (69), Expect = 3.6
Identities = 36/157 (22%), Positives = 53/157 (33%), Gaps = 23/157 (14%)
Query: 235 EEEEEEEEEEEEEEEYEQDER----------DQKEEGNDYDTRSEASDSGSESVSFT--- 281
EEEEEE EE E EE Q+ + +E + Y SE VS T
Sbjct: 788 EEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLS 847
Query: 282 ----------DGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYAGSEKKHE 331
S S G G +K + + S ++ + + S+ E Y +K E
Sbjct: 848 KQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKSE 907
Query: 332 KLSSSVRAVRKDQTSKLKYVLQDARFFLIKSNNHENV 368
+ + + QD + L K E V
Sbjct: 908 ATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGV 944
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 73.9 bits (180), Expect = 5e-13
Identities = 73/300 (24%), Positives = 125/300 (41%), Gaps = 37/300 (12%)
Query: 3 ADSREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKP 62
A +++DG+ +D E D+E E +Q+ N+ + +R+ + + +
Sbjct: 279 ASRLDDEDGDFQPQED----EEEDDEETIEVEEQQEGNDAEAQRREIELLRREGELPLEE 334
Query: 63 SVHSR--QLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSS 120
+ S QL+ P S S + + S T EE E + L+ +
Sbjct: 335 LLRSLPPQLLEGPSSPSQTPSSH------DSDTRDGPEEGAEEEPPQVLEIKPPPSAVTQ 388
Query: 121 ASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEE-- 178
+++P+ + + E + T E++ EVD S + + E++ EE
Sbjct: 389 RNKQPWHPDEDDEEFTANEEEAEDEEDTIAAEEQLEGEVDHAMELSELAREGELSMEELL 448
Query: 179 --YGSDHETGSSGSSDEQ-----GNNTENEEEG---VEEDVEEDEEVEEDAEEDEEVDED 228
Y + GS S DE N+++ E EG EE +ED + D+ ED DE+
Sbjct: 449 QQYAGAYAPGSGSSEDEDEDEVDANSSDCEPEGPVEAEEPPQEDSSSQSDSVEDRSEDEE 508
Query: 229 GEEEEEEEEE----EEEEEEEEEEEYE-QDERDQKEEGNDY--------DTRSEASDSGS 275
E EEEE EE E EE E+ + Q + D++EE +D+ D +D+GS
Sbjct: 509 DEHSEEEETSGSSASEESESEESEDAQSQSQADEEEEDDDFGVEYLLARDEEQSEADAGS 568
Score = 49.7 bits (117), Expect = 1e-05
Identities = 58/246 (23%), Positives = 95/246 (38%), Gaps = 50/246 (20%)
Query: 119 SSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEE 178
SS S+ P + + + PE A+ P LE+ S +Q +K+ + +E
Sbjct: 348 SSPSQTPSSHDSDT----RDGPEEGAEEEPPQV-----LEIKPPPSAVTQRNKQPWHPDE 398
Query: 179 YGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEE 238
DE+ E E E E+ + +E++E + + E+ E E E EE
Sbjct: 399 ------------DDEEFTANEEEAEDEEDTIAAEEQLEGEVDHAMELSELAREGELSMEE 446
Query: 239 EEEE------------EEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVR 286
++ E+E+E+E + + D + EG DS S+S S D S
Sbjct: 447 LLQQYAGAYAPGSGSSEDEDEDEVDANSSDCEPEGPVEAEEPPQEDSSSQSDSVEDRS-- 504
Query: 287 SGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYAGSEKKHEKLSSSVRAVRKDQTS 346
D DE +E + SGSSASE E + + S +D
Sbjct: 505 ----EDEEDEHSEEE-----------ETSGSSASEESESEESEDAQSQSQADEEEEDDDF 549
Query: 347 KLKYVL 352
++Y+L
Sbjct: 550 GVEYLL 555
Score = 42.7 bits (99), Expect = 0.001
Identities = 50/209 (23%), Positives = 95/209 (45%), Gaps = 14/209 (6%)
Query: 95 YKNEEYQRSERNKRLDADRKIRLSSSASRE--PYKNQPEKTCVRKRDP--ERRAKSPTPD 150
+ E+ Q+ ER +R + + R++S+ +++ + + EK K+ E + K
Sbjct: 172 HHEEQRQKEERARREEQAKLRRIASTMAKDVRQFWSNVEKVVQFKQQSRLEEKRKKALDL 231
Query: 151 GSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSG--SSDEQGNNTENEEEGVEED 208
+ I + ++ + SQS + + S + GS GSS SS + ++E+G +
Sbjct: 232 HLDFIVGQTEKYSDLLSQSLNQPLTSSKAGSSPCLGSSSAASSPPPPASRLDDEDGDFQP 291
Query: 209 VEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRS 268
E++EE +E+ E EE ++G + E + E E E E E+ R +
Sbjct: 292 QEDEEEDDEETIEVEE-QQEGNDAEAQRREIELLRREGELPLEELLRSLPPQ------LL 344
Query: 269 EASDSGSESVSFTDGSVRSGSGTDGSDEK 297
E S S++ S D R G +G++E+
Sbjct: 345 EGPSSPSQTPSSHDSDTRDGP-EEGAEEE 372
Score = 36.6 bits (83), Expect = 0.085
Identities = 51/249 (20%), Positives = 96/249 (38%), Gaps = 20/249 (8%)
Query: 60 QKPSVHSRQLVS-KPLSSSV---SNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKI 115
Q VH +L+S + + ++ +N KR++ + +++ + D +
Sbjct: 2157 QTRDVHIYRLISERTVEENILKKANQKRMLGDMAIEGGNFTTAYFKQQTIRELFDMPLEE 2216
Query: 116 RLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSK-EEV 174
SSS P + E+T K+ + E I +A + ++ ++ E
Sbjct: 2217 PSSSSVPSAP--EEEEETVASKQTHILEQALCRAEDEEDIRAATQAKAEQVAELAEFNEN 2274
Query: 175 NSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEE 234
+ G E G G+ DE+ + E E + E + E E + EE ++
Sbjct: 2275 DGFPAGEGEEAGRPGAEDEEMSRAEQEIAALVEQLTPIERYAMKFLEASLEEVSREELKQ 2334
Query: 235 EEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGS 294
EE+ E ++ ++ E+ R +EE E +G ES S +G GT
Sbjct: 2335 AEEQVEAARKDLDQAKEEVFRLPQEE-------EEGPGAGDES------SCGTGGGTHRR 2381
Query: 295 DEKKKERKR 303
+K K +R
Sbjct: 2382 SKKAKAPER 2390
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 73.9 bits (180), Expect = 5e-13
Identities = 72/339 (21%), Positives = 128/339 (37%), Gaps = 25/339 (7%)
Query: 28 DELYNPESEQDKNEKKGSKR-----------KSDRMESTDTKRQKPSVHSRQLVSKPLSS 76
+E N + +N++ G R + R D+ + H S S
Sbjct: 545 NESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHD----SWETRS 600
Query: 77 SVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVR 136
S R + + E + ER++R + +R R SS + ++ E+
Sbjct: 601 SYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERD--- 657
Query: 137 KRDPERRAKSPTPDGSERIG-LEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQG 195
+R ERR ER + +R R + +E E + E + + +
Sbjct: 658 ERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARERER 717
Query: 196 NNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDER 255
+ + + D + D E E + E D E + + E EE E E E E E E E E E++
Sbjct: 718 EREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERA 777
Query: 256 DQKEEGNDYDTRSEASDSGSESVSFTDGSVRSG-SGTDGSDEKKKERKRARGISPIVFD- 313
++++ + E D G + +R + DG DE+K +++ SP
Sbjct: 778 RERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQS 837
Query: 314 ----RSGSSASESYAGSEKKHEKLSSSVRAVRKDQTSKL 348
R S S++Y + K+EK + VR ++ L
Sbjct: 838 PKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSL 876
Score = 66.2 bits (160), Expect = 1e-10
Identities = 38/80 (47%), Positives = 50/80 (62%), Gaps = 2/80 (2%)
Query: 647 RYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRE 706
R RD+ R D R + + R+R RER+RE+ERDR RD RDR+ DR R+RE
Sbjct: 683 RERDRERERERERERDREREKERELERERAREREREREKERDRERD--RDRDHDRERERE 740
Query: 707 RERERLCDRDRDRGERGRYR 726
RER+R +R+R+R ER R R
Sbjct: 741 RERDREKEREREREERERER 760
Score = 65.1 bits (157), Expect = 2e-10
Identities = 42/89 (47%), Positives = 55/89 (61%), Gaps = 8/89 (8%)
Query: 641 PVPHEARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERD 700
P+ H+ R + + D R ++ RR V R R RERDRERERDR R+ R+RERD
Sbjct: 644 PIRHQGRNDEL---ERDERREE--RRVDRVDDRRDERARERDRERERDRERERERERERD 698
Query: 701 RGRDRER--ERERLCDRDRDR-GERGRYR 726
R R++ER ERER +R+R+R ER R R
Sbjct: 699 REREKERELERERAREREREREKERDRER 727
Score = 63.2 bits (152), Expect = 8e-10
Identities = 37/85 (43%), Positives = 50/85 (58%), Gaps = 3/85 (3%)
Query: 645 EARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRD 704
+ R ++RV D R D+ R R R RER+RER+R+R ++ +RER R R+
Sbjct: 657 DERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARERE 716
Query: 705 RERERERLCDRDRDRG---ERGRYR 726
RERE+ER +RDRDR ER R R
Sbjct: 717 REREKERDRERDRDRDHDRERERER 741
Score = 60.1 bits (144), Expect = 7e-09
Identities = 35/76 (46%), Positives = 48/76 (63%), Gaps = 7/76 (9%)
Query: 651 KRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERE 710
+R D + + L R +A R R RE++R+RERDR RD+ R+RER+R RDRE+ERE
Sbjct: 694 ERERDREREKERELERERA---REREREREKERDRERDRDRDHDRERERERERDREKERE 750
Query: 711 RLCDRDRDRGERGRYR 726
R+R+ ER R R
Sbjct: 751 ----REREERERERER 762
Score = 59.3 bits (142), Expect = 1e-08
Identities = 31/52 (59%), Positives = 40/52 (76%), Gaps = 2/52 (3%)
Query: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGERGRYR 726
R R +ERDRER+RDR D R+RER+R R++ERERER +R+R+R ER R R
Sbjct: 717 REREKERDRERDRDRDHDRERERERERDREKERERERE-ERERER-ERERER 766
Score = 57.4 bits (137), Expect = 5e-08
Identities = 32/53 (60%), Positives = 40/53 (75%), Gaps = 2/53 (3%)
Query: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRG-ERGRYR 726
R R RERDRE+ER+R R+ R +RER+R R+RERERER +R R+R ER R R
Sbjct: 737 RERERERDREKEREREREER-ERERERERERERERERERERARERDKERERQR 788
Score = 57.0 bits (136), Expect = 6e-08
Identities = 35/81 (43%), Positives = 47/81 (58%), Gaps = 2/81 (2%)
Query: 647 RYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRE 706
R RD R D+D + R + R RER+RERER+R R+ R+RER R RD+E
Sbjct: 725 RERD-RDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKE 783
Query: 707 RERER-LCDRDRDRGERGRYR 726
RER+R D+D+ R +R R
Sbjct: 784 RERQRDWEDKDKGRDDRREKR 804
Score = 53.9 bits (128), Expect = 5e-07
Identities = 28/53 (52%), Positives = 40/53 (75%), Gaps = 2/53 (3%)
Query: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDRER-ERERLCDRDRDRGERGRYR 726
+ R RERDR+R+ DR R+ R+R+R++ R+RER ERER +R+R+R ER R R
Sbjct: 721 KERDRERDRDRDHDRERERERERDREKEREREREERERERERERER-ERERER 772
Score = 51.2 bits (121), Expect = 3e-06
Identities = 61/219 (27%), Positives = 81/219 (36%), Gaps = 41/219 (18%)
Query: 527 EPVRDVGRRRPEDYDIHNSRK-KPRIDYPPEFHQRPGYLKDPRYQEVDRRFSGVRRDVFL 585
E RD G+ R D++ ++ KPR P H P + + + S ++R
Sbjct: 292 EKTRD-GKDRGRDFERQREKRDKPRSTSPAGQHHSP--ISSRHHSSSSQSGSSIQR---- 344
Query: 586 NGSYNDYVREFHNMGPPPPWQGMPPYPGMEQPPHH----PYYQHHAPPPQAHPPYSGHHP 641
H+ P P Y PP PY H PQ P
Sbjct: 345 -----------HSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRK-----QSP 388
Query: 642 VPHEARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERD------RPRDNRR 695
H + R+K HD++ RR + R R RE+D ER+ RD+R
Sbjct: 389 PRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRD 448
Query: 696 DRERDRGRDRE-----RERERLCD-RD-RDRGERGRYRR 727
DRE GRDR R+R L D RD RD E Y R
Sbjct: 449 DREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSR 487
Score = 51.2 bits (121), Expect = 3e-06
Identities = 33/80 (41%), Positives = 40/80 (50%), Gaps = 9/80 (11%)
Query: 640 HPVPHEARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRER 699
H E RD R ++D D R+R R+R RERER+R RD RRD +R
Sbjct: 1307 HDRERERERRDTRQREWDRDADK---------DWPRNRDRDRLRERERERERDKRRDLDR 1357
Query: 700 DRGRDRERERERLCDRDRDR 719
+R R ER DRDRDR
Sbjct: 1358 ERERLISDSVERDRDRDRDR 1377
Score = 50.8 bits (120), Expect = 4e-06
Identities = 67/320 (20%), Positives = 117/320 (36%), Gaps = 28/320 (8%)
Query: 27 DDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNKRIVS 86
+D + +Q ++ GS R + T + + PS S + S KR++
Sbjct: 1176 EDAQHRKPMDQKRSSSLGSNRSN--RSHTSGRLRSPSNDS----AHRSGDDQSGRKRVLH 1229
Query: 87 TKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKS 146
+ + + K+ E ER R+D ++ S S S + ++ + R+ PE +
Sbjct: 1230 SGSRDREKTKSLEIT-GERKSRIDQLKRGEPSRSTSSDRQDSRSHSS--RRSSPESDRQV 1286
Query: 147 PTPDGS--------ERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNT 198
+ GS ER E DR R + +++ + D +
Sbjct: 1287 HSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERE 1346
Query: 199 ENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQK 258
++ + D E + + + E D + D D E + E + E + E E+E+D
Sbjct: 1347 RERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTS 1406
Query: 259 EEGNDYDTRSEASDSGS-ESVSFTDGSVRSGSGTDGSDEKKKERKRA------RGISPIV 311
+ D D GS + T+ S R+ S G DE K + + G PI
Sbjct: 1407 RDSLALDKERMDKDLGSVQGFEETNKSERTESLEAGDDESKLDDAHSLGSGAGEGYEPI- 1465
Query: 312 FDRSGSSASESYAGSEKKHE 331
S E AG +K E
Sbjct: 1466 ---SDDELDEILAGDAEKRE 1482
Score = 49.3 bits (116), Expect = 1e-05
Identities = 36/96 (37%), Positives = 45/96 (46%), Gaps = 29/96 (30%)
Query: 650 DKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRE--------------------RERDR 689
D++VH R F R + R RER+RE R+RDR
Sbjct: 1283 DRQVHS---RSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDR 1339
Query: 690 PRDNRRDRERDRGRDRERERERLC------DRDRDR 719
R+ R+RERD+ RD +RERERL DRDRDR
Sbjct: 1340 LRERERERERDKRRDLDRERERLISDSVERDRDRDR 1375
Score = 48.1 bits (113), Expect = 3e-05
Identities = 64/239 (26%), Positives = 85/239 (35%), Gaps = 32/239 (13%)
Query: 519 SRGRPSRREPVRDVGRRRPEDYDIHNSRKKPRIDYPPEFHQRPGYLKDPRYQEVDRRFSG 578
SR RE +RD R E D +SR + R + K+ Y E R +
Sbjct: 473 SRDMRDSRE-MRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGR 531
Query: 579 VR------RDVFLNGSYNDYVREFHN--MG------PPPPWQGMPPYPGMEQPPHHPYYQ 624
R N S N+ E N MG P P +G G + H
Sbjct: 532 NHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSN 591
Query: 625 HHAPPPQAHPPYSGHHPVPHEARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRP------ 678
+H + Y P R ++ R + RR R S P
Sbjct: 592 YH-DSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGR 650
Query: 679 ---RERDRERER-------DRPRDNRRDRERDRGRDRERERERLCDRDRDRGERGRYRR 727
ERD RE DR + R+R+R+R RDRERERER +RDR+R + R
Sbjct: 651 NDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELER 709
Score = 47.8 bits (112), Expect = 4e-05
Identities = 69/345 (20%), Positives = 124/345 (35%), Gaps = 63/345 (18%)
Query: 8 EKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSR 67
EK E+ + ++ EV +P K+ K ++ S + S K +K S S
Sbjct: 186 EKREEIIIKKEVSPEVVRSK---LSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSS 242
Query: 68 QLVSKPLSSSVSNNKR----------------IVSTKGKSATEYKN--EEYQRSERNKRL 109
L+ + +S + +K+ + K K + K+ EE R +++
Sbjct: 243 PLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGR 302
Query: 110 DADR------KIRLSSSA--------SREPYKNQPEKTCVRKRDPE-RRAKSPTPDGSER 154
D +R K R +S A SR + + +++ P RR ++P+P
Sbjct: 303 DFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRT 362
Query: 155 IGLEVDRRAS-------------------RSSQSSKEEVNSEEYGSDHETGSSGSSDEQG 195
+ + R AS RS K + E H+ D +G
Sbjct: 363 LTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRG 422
Query: 196 NNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDER 255
++ E + E+D+ D +D E DG + + + + E + +D R
Sbjct: 423 KRDREKDSREEREYEQDQSSSRDHRDDRE-PRDGRDRRDARDTRDRRELRDS----RDMR 477
Query: 256 DQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKE 300
D +E DY ++ S +S S D +G D +KE
Sbjct: 478 DSREM-RDYSRDTKESRDPRDSRSTRDA--HDYRDREGRDTHRKE 519
Score = 47.4 bits (111), Expect = 5e-05
Identities = 28/64 (43%), Positives = 35/64 (54%), Gaps = 12/64 (18%)
Query: 675 RSRPRERDRERERDRPRDNRRDRER-----DRGRDRERERERLCDRDR-------DRGER 722
R R RER+RERER R RD R+R+R D+GRD RE+ DR +R +
Sbjct: 764 RERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSK 823
Query: 723 GRYR 726
RYR
Sbjct: 824 KRYR 827
Score = 47.0 bits (110), Expect = 6e-05
Identities = 55/278 (19%), Positives = 103/278 (37%), Gaps = 27/278 (9%)
Query: 34 ESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSAT 93
E E++ ++ +R+ +R + D +R + H R+ + +
Sbjct: 702 EKERELERERAREREREREKERDRERDRDRDHDRE-----------------RERERERD 744
Query: 94 EYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSE 153
K E +R ER + + +R+ RE + + +K R+RD E + K +
Sbjct: 745 REKEREREREERERERERERERERERERERERARER-DKERERQRDWEDKDKGRDDRREK 803
Query: 154 RIGLEVDR--RASRSSQSSKEEVNSEEYGSDHETG------SSGSSDEQGNNTENEEEGV 205
R + DR R + SK+ +E S ++ S S + +NE+ +
Sbjct: 804 REEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRL 863
Query: 206 EEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYD 265
V +E + D G +EE+ + E +E EE E E+ +
Sbjct: 864 LSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQ 923
Query: 266 TR-SEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERK 302
T E+S ++ + S + DE KK+ K
Sbjct: 924 TEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAK 961
Score = 45.8 bits (107), Expect = 1e-04
Identities = 56/268 (20%), Positives = 108/268 (40%), Gaps = 33/268 (12%)
Query: 32 NPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNKRIVSTKGKS 91
+PES++ + + GS DR++ D + ++ +K + +
Sbjct: 1279 SPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRD 1338
Query: 92 ATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDG 151
+ E +R +R + LD +R+ +S S R+ R RD +R +S +
Sbjct: 1339 RLRERERERERDKR-RDLDRERERLISDSVERD-----------RDRDRDRTFESSQIES 1386
Query: 152 SERIGLEVDRRASRSSQS-SKEEVNSEEYGSDHETGSSGSSDE--QGNNTENEEEGVEED 208
+R +++ R +S S++ + ++ D + GS +E + TE+ E G +E
Sbjct: 1387 VKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSERTESLEAGDDES 1446
Query: 209 VEEDE-----------EVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQ 257
+D E D E DE + D E+ E++++EE+ + D D
Sbjct: 1447 KLDDAHSLGSGAGEGYEPISDDELDEILAGDAEKREDQQDEEKMPD-------PLDVIDV 1499
Query: 258 KEEGNDYDTRSEASDSGSESVSFTDGSV 285
G E + G+ + FT G+V
Sbjct: 1500 DWSGLMPKHPKEPREPGAALLKFTPGAV 1527
Score = 45.1 bits (105), Expect = 2e-04
Identities = 51/226 (22%), Positives = 93/226 (41%), Gaps = 32/226 (14%)
Query: 137 KRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGN 196
+R PER PT D ER+ ++ +++V++E + E SS E
Sbjct: 75 RRSPER----PTGDLRERM------------KNKRQDVDTEPQKRNTEESSSPVRKESSR 118
Query: 197 NTENEEEGVEEDVE-----EDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYE 251
E+E ++ E E+E VE + D+ + D + E E + ++ + E
Sbjct: 119 GRHREKEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELM 178
Query: 252 QDERDQKEEGNDYDTRSEASD-------SGSESVSFTDGSVRSGSGTDGSDEKKKERKRA 304
+ E++ E+ + + E S S S S+ + S + S S KK+RK +
Sbjct: 179 KLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTS 238
Query: 305 RGISPIVFDRSGSSASESYAGSEKKHEKLSSSVRAVRKDQTSKLKY 350
SP++ + S ++ S+KK + S + +D KY
Sbjct: 239 AVSSPLLDQQRNSKTNQ----SKKKGPRTPSPPPPIPEDIALGKKY 280
Score = 43.9 bits (102), Expect = 5e-04
Identities = 31/58 (53%), Positives = 35/58 (60%), Gaps = 15/58 (25%)
Query: 680 ERDRERERDRPRDNR-------------RDRERDRGRDRERERERLCDRDRDRGERGR 724
E DRERER+R RD R R+R+RDR R+RERERER RD DR ER R
Sbjct: 1306 EHDRERERER-RDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDR-ERER 1361
Score = 43.5 bits (101), Expect = 7e-04
Identities = 53/264 (20%), Positives = 96/264 (36%), Gaps = 18/264 (6%)
Query: 40 NEKKGSKRKSDRMESTDTKRQ--KPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKN 97
NE K R+E +T + + H + + K SS SN T G+ + +
Sbjct: 1153 NEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSND 1212
Query: 98 EEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGL 157
++ + D + R+ S SR+ K + + ++ + K P S
Sbjct: 1213 SAHRSGD-----DQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRST---- 1263
Query: 158 EVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEE 217
DR+ SRS S + S+ SGS D + E + + + E +
Sbjct: 1264 SSDRQDSRSHSSRRSSPESDRQVHSR----SGSFDSRDRLQERDRYEHDRERERERRDTR 1319
Query: 218 DAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSES 277
E D + D+D + + E E E E ++ +R+++ +D R D
Sbjct: 1320 QREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRD---RD 1376
Query: 278 VSFTDGSVRSGSGTDGSDEKKKER 301
+F + S + E + ER
Sbjct: 1377 RTFESSQIESVKRCEAKLEGEHER 1400
Score = 40.0 bits (92), Expect = 0.008
Identities = 50/261 (19%), Positives = 113/261 (43%), Gaps = 19/261 (7%)
Query: 4 DSREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPS 63
D E+ + D + E+ +E+ + +D ++++ SK++ R E + + RQ P
Sbjct: 781 DKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRY-RNEGSPSPRQSPK 839
Query: 64 VHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASR 123
R+ P S N+ + K + ++ + RS L DR+ R R
Sbjct: 840 ---RRREHSP-DSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEE-DR 894
Query: 124 EPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDH 183
+P + + + R + E + K + D +R E+ SS+ +++ D
Sbjct: 895 KPERKESSR---RYEEQELKEKVSSVD-KQREQTEI----LESSRMRAQDIIGHHQSEDR 946
Query: 184 ETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVE----EDAEEDEEVDEDGEEEEEEEEEE 239
ET S + DE + +++ +++ E+D +E E ED +V + ++++ E+
Sbjct: 947 ET-SDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEK 1005
Query: 240 EEEEEEEEEEYEQDERDQKEE 260
+ ++ + + + +E Q+ +
Sbjct: 1006 KRKKSKGDSDISDEEAAQQSK 1026
Score = 32.7 bits (73), Expect = 1.2
Identities = 50/266 (18%), Positives = 106/266 (39%), Gaps = 26/266 (9%)
Query: 32 NPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNKRIVSTKGKS 91
+P Q ++ SD S D K +K + S Q+V S S+S + +G+
Sbjct: 831 SPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLS-QVVRPQESRSLSPSHLTEDRQGRW 889
Query: 92 ATEYKNEE-------YQRSERNKRLDADRKIR-----LSSSASREP-----YKNQPEKTC 134
E + E Y+ E +++ + K R L SS R ++++ +T
Sbjct: 890 KEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETS 949
Query: 135 VRKRDPERRA----KSPTPDGSER-IGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSG 189
R D ++ K P E +G+E R + + S +V S + G ++
Sbjct: 950 DRAHDENKKKAKIQKKPIKKKKEDDVGIE---RGNIETTSEDGQVFSPKKGQKKKSIEKK 1006
Query: 190 SSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEE 249
+G++ ++EE ++ ++ EE+ E + E+ +++E+ +
Sbjct: 1007 RKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKEDTAFSD 1066
Query: 250 YEQDERDQKEEGNDYDTRSEASDSGS 275
+ ++ + E + + + A+ GS
Sbjct: 1067 WSDEDVPDRTEVTEAEHTATATTPGS 1092
Score = 31.2 bits (69), Expect = 3.6
Identities = 53/302 (17%), Positives = 103/302 (34%), Gaps = 38/302 (12%)
Query: 5 SREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSV 64
++EE N + IL + +++D ++ S++D ++ +++ + T PS
Sbjct: 1038 TKEELVEMCNGKNGILEDSQKKEDTAFSDWSDEDVPDRT-EVTEAEHTATATTPGSTPSP 1096
Query: 65 HSRQLVSKP---LSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSA 121
S L P +++ + + +T +AT + S + + +
Sbjct: 1097 LSSLLPPPPPVATATATTVPATLAATTAAAATSFSTSAITISTSATPTNTTNNTFANEDS 1156
Query: 122 SREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGS 181
R+ ++ + EK D R ++ R +S S S S S
Sbjct: 1157 HRKCHRTRVEKV--------ETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRS 1208
Query: 182 DHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEE 241
+ S D+Q G D E+ + ++ GE + ++ +
Sbjct: 1209 PSNDSAHRSGDDQSGRKRVLHSG-----------SRDREKTKSLEITGERKSRIDQLKRG 1257
Query: 242 EEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKER 301
E QD R S S S +D V S SG+ S ++ +ER
Sbjct: 1258 EPSRSTSSDRQDSR---------------SHSSRRSSPESDRQVHSRSGSFDSRDRLQER 1302
Query: 302 KR 303
R
Sbjct: 1303 DR 1304
>gi|31377750 YTH domain family, member 1 [Homo sapiens]
Length = 559
Score = 73.6 bits (179), Expect = 6e-13
Identities = 55/189 (29%), Positives = 88/189 (46%), Gaps = 19/189 (10%)
Query: 312 FDRSGSSASESY---------AGSEKKHEKLSSSVRAVRKDQTSKLKYVLQDARFFLIKS 362
F +SG + S+S A S + H L ++A + ++ L+ R F+IKS
Sbjct: 338 FGQSGGAGSDSNSPGNVQPNSAPSVESHPVLEK-LKAAHSYNPKEFEWNLKSGRVFIIKS 396
Query: 363 NNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARS---VILIFSVRESGKFQGFARLSSES 419
+ +++ + +W + K+L+ AFR S V L+FSV SG F G A + S
Sbjct: 397 YSEDDIHRSIKYSIWCSTEHGNKRLDSAFRCMSSKGPVYLLFSVNGSGHFCGVAEMKSPV 456
Query: 420 HHGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQE 479
+G S W S G F + WI +++P + H+ N++KPV RD QE
Sbjct: 457 DYGTSAGVW------SQDKWKGKFDVQWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQE 510
Query: 480 IELECGTQL 488
+ LE Q+
Sbjct: 511 VPLEKAKQV 519
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 72.8 bits (177), Expect = 1e-12
Identities = 58/312 (18%), Positives = 127/312 (40%), Gaps = 9/312 (2%)
Query: 22 EVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNN 81
+ + D E+D++ K+ R+ R + +RQ RQ + +
Sbjct: 70 QTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKE--RNRQKER 127
Query: 82 KRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPE 141
+R +G+ + + + + ER + + +R+ + R+ +N+ ++ R+R+
Sbjct: 128 ERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKE---REREKN 184
Query: 142 RRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENE 201
R+ + E+ DR + R + +E E ++ + + D Q
Sbjct: 185 RQERRERERQREKENKTEDRHSERGRERERERETETE--TERKRQTDRERDRQRKTERER 242
Query: 202 EEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQD-ERDQKEE 260
E+ E + + E E D E + E D D + + ++E E + + + + E+D E ++K E
Sbjct: 243 EKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRE 302
Query: 261 GNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSAS 320
R + E + T+ EK++ERKR R + + +R+ +
Sbjct: 303 RQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQ-TEMDRERNRQTGR 361
Query: 321 ESYAGSEKKHEK 332
E +E++ E+
Sbjct: 362 EGRRQAERERER 373
Score = 71.2 bits (173), Expect = 3e-12
Identities = 69/335 (20%), Positives = 127/335 (37%), Gaps = 41/335 (12%)
Query: 36 EQDKNEKKGSKRKSDRMESTDTKR--QKPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSAT 93
++D++ ++ R+ +R TD +R Q+ +RQ + + R T G+
Sbjct: 90 KRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRER 149
Query: 94 EYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSE 153
E + + + ER + R+ + RE KN+ E+ R+R+ +R ++ T D
Sbjct: 150 ERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQER---RERERQREKENKTEDRHS 206
Query: 154 RIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDE 213
G E +R +++ ++ E D + + ++Q E E D E +
Sbjct: 207 ERGRERERERETETETERKRQTDRE--RDRQRKTEREREKQAERERASERETERDKERER 264
Query: 214 EVEED---------------------AEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQ 252
E + D E D E + E + E E E E + E E +
Sbjct: 265 ERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERE 324
Query: 253 DERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGISPIVF 312
ER+++ E + D E D +G +G + ++ER+R R
Sbjct: 325 RERERQRE-TERDREKERERKRKRQTEM-DRERNRQTGREGRRQAERERERER------- 375
Query: 313 DRSGSSASESYAGSEKKHEKLSSSVRAVRKDQTSK 347
+R SA E E++ + R+ QT K
Sbjct: 376 ERDRQSARE----REERERDRDRDRQKERERQTEK 406
Score = 70.9 bits (172), Expect = 4e-12
Identities = 65/284 (22%), Positives = 113/284 (39%), Gaps = 30/284 (10%)
Query: 34 ESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSAT 93
E+E + K+ + R+ DR T+ +R+K + R ++ + K +
Sbjct: 217 ETETETERKRQTDRERDRQRKTEREREKQAERER-----------ASERETERDKERERE 265
Query: 94 EYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSE 153
++ + R ++ + DRK + + RE + + E+ R+R+ ER K E
Sbjct: 266 RDRDRDRDRRQKERERQTDRKRQRRTERDRETERKR-ERQRERERERERNRKRERERERE 324
Query: 154 RIGLEVDRRASRSSQSSKEEVNSEEYGSDHE----TGSSGSSDEQGNNTENEEEGVEEDV 209
R E R R + +E + D E TG G + E E E +
Sbjct: 325 R-ERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAE-RERERERERDRQSA 382
Query: 210 EEDEEVEEDAEEDE--------EVDEDGEEEEEEEEEEEEEEEEE---EEEYEQDERDQK 258
E EE E D + D E D DG+ E E++ E E++ E E E E++++ +
Sbjct: 383 REREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGR 442
Query: 259 EEGNDYDTRSEASDSGSESVSFTDGSVRSG-SGTDGSDEKKKER 301
E + T +A S + + R+ SG SD + R
Sbjct: 443 ERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTR 486
Score = 67.0 bits (162), Expect = 6e-11
Identities = 83/405 (20%), Positives = 155/405 (38%), Gaps = 52/405 (12%)
Query: 34 ESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNKRI-VSTKGKSA 92
+ + ++N +K +R+ +R E + +RQ+ + + + T+ K
Sbjct: 168 QRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQ 227
Query: 93 TEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGS 152
T+ + + +++ER + A+R+ R+ + E+ R RD +RR K
Sbjct: 228 TDRERDRQRKTEREREKQAERERASERETERD---KERERERDRDRDRDRRQKE-----R 279
Query: 153 ERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEED 212
ER + DR+ R ++ +E E + E + + N E E + E
Sbjct: 280 ER---QTDRKRQRRTERDRETERKRERQRERER------ERERNRKRERERERERERERQ 330
Query: 213 EEVEEDAEEDEEVDEDGEEEEEEEE------------EEEEEEEEEEEEYEQDERDQKEE 260
E E D E++ E + E + E E E E E E + ER+++E
Sbjct: 331 RETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERER 390
Query: 261 GNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSAS 320
D D + E ++ DG T+ E++K+R+ RG R
Sbjct: 391 DRDRDRQKERE---RQTEKDRDGQ----RETEKQREREKDRESERG-------RERGRER 436
Query: 321 ESYAGSEKKHEKLSS-SVRAVRKDQTSKLKYVLQDARFFLIKSNNHENVSLAKAKGV-WS 378
E G E+ E+ + RK T + + AR +++S+ + +G+ W
Sbjct: 437 EKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNR-----PTRGIRWK 491
Query: 379 TLPVNEKKLNLAFRSARSVILIFSVRESGKFQGFARLSSESHHGG 423
+ P + K + F R R +G+ + RL + GG
Sbjct: 492 SSPEDPKAASTRFPWGRPA-KASRGRVAGRRRWEPRLGEKRGQGG 535
Score = 65.1 bits (157), Expect = 2e-10
Identities = 65/343 (18%), Positives = 133/343 (38%), Gaps = 34/343 (9%)
Query: 8 EKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSR 67
+++ E N + E + + + +++ + ++ + +R TD +RQ+ + +R
Sbjct: 116 QREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNR 175
Query: 68 QLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASRE-PY 126
Q + + K+ E + E QR + NK D + RE
Sbjct: 176 QKERE---------------REKNRQERRERERQREKENKTEDRHSERGRERERERETET 220
Query: 127 KNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETG 186
+ + ++ R+RD +R+ + +ER +R + R ++ KE + D +
Sbjct: 221 ETERKRQTDRERDRQRKTEREREKQAER-----ERASERETERDKERERERDRDRDRD-- 273
Query: 187 SSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEE 246
+ + + E D E + + E E + E + + + E E E E E E + E
Sbjct: 274 -RRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRE 332
Query: 247 EEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARG 306
E + ER++K + R +G E R + + E++++R+ AR
Sbjct: 333 TERDREKERERKRKRQTEMDRERNRQTGREG--------RRQAERERERERERDRQSARE 384
Query: 307 ISPIVFDRSGSSASESYAGSEKKH--EKLSSSVRAVRKDQTSK 347
DR E +EK ++ + R KD+ S+
Sbjct: 385 REERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESE 427
Score = 63.2 bits (152), Expect = 8e-10
Identities = 35/81 (43%), Positives = 52/81 (64%), Gaps = 4/81 (4%)
Query: 647 RYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRE 706
R RD+R + + + D R+ Q R R+R+R+RER+R R+ R RER+R R+RE
Sbjct: 270 RDRDRRQKERERQTD---RKRQRRTERDRETERKRERQRERERERERNRKRERERERERE 326
Query: 707 RERERLCDRDRDRGERGRYRR 727
RER+R +RDR++ ER R R+
Sbjct: 327 RERQRETERDREK-ERERKRK 346
Score = 62.0 bits (149), Expect = 2e-09
Identities = 40/108 (37%), Positives = 58/108 (53%), Gaps = 20/108 (18%)
Query: 631 QAHPPYSGHHPVPHEARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRP 690
QAH G + + R++R R+T+ +R R RE+DR R+RDR
Sbjct: 44 QAHKDADGDDRERNRQKERERRREK---------RQTERETDRKRERRREKDRHRKRDRH 94
Query: 691 RDNRRDRER------DRGRDRERERERLCDRDRDR-----GERGRYRR 727
R+ +RDRE+ DR RDR+RE+ER ++R+R GERGR R+
Sbjct: 95 RERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQ 142
Score = 58.2 bits (139), Expect = 3e-08
Identities = 29/56 (51%), Positives = 41/56 (73%), Gaps = 3/56 (5%)
Query: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDR---GERGRYRR 727
R R RE++RER+ DR RD +R++ER+R ++RERE ER +R RDR G+R R R+
Sbjct: 97 RQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQ 152
Score = 58.2 bits (139), Expect = 3e-08
Identities = 34/74 (45%), Positives = 41/74 (55%), Gaps = 3/74 (4%)
Query: 649 RDK---RVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDR 705
RDK R D D D + + +R R ERDRE ER R R R+RER+R R R
Sbjct: 258 RDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKR 317
Query: 706 ERERERLCDRDRDR 719
ERERER +R+R R
Sbjct: 318 ERERERERERERQR 331
Score = 57.8 bits (138), Expect = 4e-08
Identities = 30/67 (44%), Positives = 43/67 (64%), Gaps = 4/67 (5%)
Query: 665 RRTQAVVSGRRSRPRERDRERERDRPRDNRRDRER----DRGRDRERERERLCDRDRDRG 720
R T+ +R RERDR+R+ +R R+ + +RER + RD+ERERER DRDRDR
Sbjct: 216 RETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRR 275
Query: 721 ERGRYRR 727
++ R R+
Sbjct: 276 QKERERQ 282
Score = 56.6 bits (135), Expect = 8e-08
Identities = 29/64 (45%), Positives = 41/64 (64%), Gaps = 4/64 (6%)
Query: 665 RRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDR----G 720
R Q R R R+R+RERER+R R+ +R+ ERDR ++RER+R+R + DR+R G
Sbjct: 301 RERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTG 360
Query: 721 ERGR 724
GR
Sbjct: 361 REGR 364
Score = 54.3 bits (129), Expect = 4e-07
Identities = 50/255 (19%), Positives = 100/255 (39%), Gaps = 35/255 (13%)
Query: 95 YKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSER 154
+K+ + ERN++ + +R+ RE K Q E+ RKR+ R
Sbjct: 46 HKDADGDDRERNRQKERERR--------RE--KRQTERETDRKRERRR------------ 83
Query: 155 IGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEE 214
E DR R ++ +E + +++ N + E E + E +
Sbjct: 84 ---EKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRD 140
Query: 215 VEEDAEEDEEVDEDGEEEEE-----EEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSE 269
+ D + + E D E+E E E + + E ++E E E++ ++++E + ++
Sbjct: 141 RQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENK 200
Query: 270 ASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYAGSEKK 329
D SE + + + T+ + +ER R R +R +E SE++
Sbjct: 201 TEDRHSERGRERERERETETETERKRQTDRERDRQRKT-----EREREKQAERERASERE 255
Query: 330 HEKLSSSVRAVRKDQ 344
E+ R +D+
Sbjct: 256 TERDKERERERDRDR 270
Score = 54.3 bits (129), Expect = 4e-07
Identities = 26/56 (46%), Positives = 39/56 (69%), Gaps = 1/56 (1%)
Query: 672 SGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRG-ERGRYR 726
S R RERDR+R+R + R+ + +++RD R+ E++RER DR+ +RG ERGR R
Sbjct: 381 SAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRER 436
Score = 53.9 bits (128), Expect = 5e-07
Identities = 29/75 (38%), Positives = 45/75 (60%), Gaps = 1/75 (1%)
Query: 646 ARYRDKRVHDYDM-RVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRD 704
AR R++R D D R + R+T+ G+R ++R+RE++R+ R R RER++ +
Sbjct: 382 AREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKG 441
Query: 705 RERERERLCDRDRDR 719
RER+RER DR R
Sbjct: 442 RERDRERQTDRQAGR 456
Score = 53.1 bits (126), Expect = 9e-07
Identities = 32/76 (42%), Positives = 38/76 (50%), Gaps = 3/76 (3%)
Query: 647 RYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRE 706
R R+ R D R Q R + ER+R ER+ RD R+RERDR RDR+
Sbjct: 214 RERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRD 273
Query: 707 R---ERERLCDRDRDR 719
R ERER DR R R
Sbjct: 274 RRQKERERQTDRKRQR 289
Score = 52.0 bits (123), Expect = 2e-06
Identities = 29/81 (35%), Positives = 46/81 (56%), Gaps = 2/81 (2%)
Query: 647 RYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRE 706
R RD++ R + R T+ G R R R+ D +RER+R RD ++RER R+R+
Sbjct: 111 RERDRQREKERNRQKERERETER--EGERGRDRQTDGQRERERQRDAEKERERQTDRERQ 168
Query: 707 RERERLCDRDRDRGERGRYRR 727
R+ ER ++R+R + + RR
Sbjct: 169 RQTERNRQKEREREKNRQERR 189
Score = 50.8 bits (120), Expect = 4e-06
Identities = 25/54 (46%), Positives = 35/54 (64%), Gaps = 3/54 (5%)
Query: 673 GRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGERGRYR 726
G+R R R+RD E+ER+R D R R+ +R R +ERERE+ ++R ER R R
Sbjct: 145 GQRERERQRDAEKERERQTDRERQRQTERNRQKEREREK---NRQERRERERQR 195
Score = 49.7 bits (117), Expect = 1e-05
Identities = 31/67 (46%), Positives = 39/67 (58%), Gaps = 18/67 (26%)
Query: 677 RPRERDRERERDRPRDNR-----------------RDRERDRGRDRERERERLCDRDRDR 719
R +ER+RER+RDR RD R RDRE +R R+R+RERER +R+R R
Sbjct: 258 RDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKR 317
Query: 720 GERGRYR 726
ER R R
Sbjct: 318 -ERERER 323
Score = 49.3 bits (116), Expect = 1e-05
Identities = 35/91 (38%), Positives = 48/91 (52%), Gaps = 11/91 (12%)
Query: 647 RYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRP--------RDNRRD-- 696
R+R + H R + R Q R R +ER+R++ER+R RD + D
Sbjct: 87 RHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQ 146
Query: 697 RERDRGRDRERERERLCDRDRDR-GERGRYR 726
RER+R RD E+ERER DR+R R ER R +
Sbjct: 147 RERERQRDAEKERERQTDRERQRQTERNRQK 177
Score = 49.3 bits (116), Expect = 1e-05
Identities = 27/53 (50%), Positives = 32/53 (60%), Gaps = 7/53 (13%)
Query: 674 RRSRPRERDRERERDRPRDNRRDRERDRGRDRERER-------ERLCDRDRDR 719
+R R E DRER R R+ RR ER+R R+RER+R ER DRDRDR
Sbjct: 344 KRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDR 396
Score = 48.9 bits (115), Expect = 2e-05
Identities = 27/59 (45%), Positives = 38/59 (64%), Gaps = 8/59 (13%)
Query: 675 RSRPRERDRERERDRPR-------DNRRDRERDRGRDRERERERLCDRDRDRGERGRYR 726
+ R RERDR+R+RDR + D +R R +R R+ ER+RER +R+R+R ER R R
Sbjct: 260 KERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERER-ERNRKR 317
Score = 48.9 bits (115), Expect = 2e-05
Identities = 33/78 (42%), Positives = 40/78 (51%), Gaps = 26/78 (33%)
Query: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDR----------------------ERERERL 712
R R RER+RERER+R R+ RDRE++R R R ERERER
Sbjct: 315 RKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERE 374
Query: 713 CDRD----RDRGERGRYR 726
+RD R+R ER R R
Sbjct: 375 RERDRQSAREREERERDR 392
Score = 48.5 bits (114), Expect = 2e-05
Identities = 34/94 (36%), Positives = 48/94 (51%), Gaps = 13/94 (13%)
Query: 647 RYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDR----ERERDRPRDNR-RDRERDR 701
R R + R D R+ Q + ++ R RE++R ERER R ++N+ DR +R
Sbjct: 149 RERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSER 208
Query: 702 GRDRERERE--------RLCDRDRDRGERGRYRR 727
GR+RERERE R DR+RDR + R
Sbjct: 209 GRERERERETETETERKRQTDRERDRQRKTERER 242
Score = 48.5 bits (114), Expect = 2e-05
Identities = 27/57 (47%), Positives = 38/57 (66%), Gaps = 2/57 (3%)
Query: 672 SGRRSRPRERDRERERDRPRD-NRRDRERDRGRDRERERERLCDRDRDR-GERGRYR 726
+ R R+++RERERDR RD +RR +ER+R DR+R+R DR+ +R ER R R
Sbjct: 251 ASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRER 307
Score = 48.5 bits (114), Expect = 2e-05
Identities = 29/85 (34%), Positives = 45/85 (52%), Gaps = 10/85 (11%)
Query: 645 EARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRR--------- 695
E R + +R + + D R + R R R+++RER+ ++ RD +R
Sbjct: 362 EGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQRERE 421
Query: 696 -DRERDRGRDRERERERLCDRDRDR 719
DRE +RGR+R RERE+ R+RDR
Sbjct: 422 KDRESERGRERGREREKQKGRERDR 446
Score = 47.8 bits (112), Expect = 4e-05
Identities = 23/54 (42%), Positives = 33/54 (61%)
Query: 674 RRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGERGRYRR 727
+ R RE+ ERER R+ RD+ER+R RDR+R+R+R + +R R RR
Sbjct: 237 KTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRR 290
Score = 47.4 bits (111), Expect = 5e-05
Identities = 27/72 (37%), Positives = 40/72 (55%), Gaps = 4/72 (5%)
Query: 659 RVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRD-- 716
R D R + + R R+ DRER+R R+ +++RER++ R RERER +++
Sbjct: 141 RQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENK 200
Query: 717 -RDR-GERGRYR 726
DR ERGR R
Sbjct: 201 TEDRHSERGRER 212
Score = 47.4 bits (111), Expect = 5e-05
Identities = 23/54 (42%), Positives = 36/54 (66%), Gaps = 1/54 (1%)
Query: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRG-ERGRYRR 727
R + RER E++RD R+ + RER++ R+ ER RER +R++ +G ER R R+
Sbjct: 396 RQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQ 449
Score = 47.0 bits (110), Expect = 6e-05
Identities = 28/78 (35%), Positives = 44/78 (56%), Gaps = 1/78 (1%)
Query: 647 RYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRE 706
R R++R R D R Q R R +R+R+R+R++ R+ +++RER+ R+ E
Sbjct: 77 RKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGE 136
Query: 707 RERERLCDRDRDRGERGR 724
R R+R D R+R ER R
Sbjct: 137 RGRDRQTDGQRER-ERQR 153
Score = 46.2 bits (108), Expect = 1e-04
Identities = 26/69 (37%), Positives = 39/69 (56%), Gaps = 12/69 (17%)
Query: 665 RRTQAVVSGRRSRPRERDRERERDRPRDNRR-----------DRERDRGRDRERERERLC 713
R+ Q + R+R R+ R+ +R R+ R +RERDR RDR++ERER
Sbjct: 345 RKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQT 404
Query: 714 DRDRDRGER 722
++DRD G+R
Sbjct: 405 EKDRD-GQR 412
Score = 44.3 bits (103), Expect = 4e-04
Identities = 25/63 (39%), Positives = 37/63 (58%), Gaps = 12/63 (19%)
Query: 674 RRSRPRERDRE-----------RERDRPRDNRRDRERDRGRDRERERERLCDRDRDR-GE 721
RR R R+R++E RER+R R+ + ER R DRER+R+R +R+R++ E
Sbjct: 188 RRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAE 247
Query: 722 RGR 724
R R
Sbjct: 248 RER 250
Score = 41.6 bits (96), Expect = 0.003
Identities = 36/173 (20%), Positives = 67/173 (38%), Gaps = 18/173 (10%)
Query: 144 AKSPTPDGSERIG-----LEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNT 198
AK P ++++G + + SR S+E G H+ D++ N
Sbjct: 2 AKKIVPATADQLGTLWVEVTIPLDFSRRRPGSQESPRRRGLGQAHK---DADGDDRERNR 58
Query: 199 ENEEEGVEEDVEEDEEVEEDAEEDEEVDEDG------EEEEEEEEEEEEEEEEEEEEYEQ 252
+ E E E + + E + E E D E + + E+E E + + E + +
Sbjct: 59 QKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQRE 118
Query: 253 DERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRAR 305
ER++++E + +T E TDG D E++++ R R
Sbjct: 119 KERNRQKE-RERETEREGERGRDRQ---TDGQRERERQRDAEKERERQTDRER 167
Score = 32.3 bits (72), Expect = 1.6
Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 2/67 (2%)
Query: 662 DFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRD-RG 720
DF RR R R + + R+ R +ER+R R++ R+ ER DR R+ R
Sbjct: 25 DFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREK-RQTERETDRKRERRR 83
Query: 721 ERGRYRR 727
E+ R+R+
Sbjct: 84 EKDRHRK 90
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 72.8 bits (177), Expect = 1e-12
Identities = 63/273 (23%), Positives = 115/273 (42%), Gaps = 11/273 (4%)
Query: 4 DSREEKDGE-LNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKP 62
D R+E+D D L E P Q E E++ E + K +R+E D +R+
Sbjct: 112 DRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDE 171
Query: 63 SVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSAS 122
+ ++ + + +++ S KG E+ +EE R R + L+ RK R
Sbjct: 172 ELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLR--RRELLELRRKGREEKQQQ 229
Query: 123 REP-----YKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSE 177
R ++ + EK ++ R+ + + + E+ + + ++E+ E
Sbjct: 230 RRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRE 289
Query: 178 EYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEE 237
+ E EQ + EEE E+ E E+ E +++E ++ E+EE
Sbjct: 290 R--QEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERR 347
Query: 238 EEEEEEEEEEEEYEQD-ERDQKEEGNDYDTRSE 269
E++ E+EEE EQ R+Q+EE + R E
Sbjct: 348 EQQLRREQEEERREQQLRREQEEERREQQLRRE 380
Score = 67.4 bits (163), Expect = 4e-11
Identities = 58/311 (18%), Positives = 134/311 (43%), Gaps = 14/311 (4%)
Query: 6 REEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVH 65
+EE++ E + +L + E+ E P+ +++ E++ RK +R E ++++
Sbjct: 239 QEEEEKEWRKRETVLRKEEEKLQE-EEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQ 297
Query: 66 SRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREP 125
R + L +R + + E + ++ +R E+ R + + R RE
Sbjct: 298 QRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEE--RREQQLRREQ 355
Query: 126 YKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRAS--------RSSQSSKEEVNSE 177
+ + E+ R+++ ERR + + R ++ R R Q +E+
Sbjct: 356 EEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 415
Query: 178 EYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEE 237
E E +E+ + ++E+E E+ ++ ++E D + EE E E+E +++
Sbjct: 416 EQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQ 475
Query: 238 EEEEEEEEEEEEY---EQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGS 294
+ ++EEE E + E++ER +++E + R E + + + + R
Sbjct: 476 LKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSE 535
Query: 295 DEKKKERKRAR 305
+ ++E++ R
Sbjct: 536 QQLRREQEERR 546
Score = 60.5 bits (145), Expect = 5e-09
Identities = 63/317 (19%), Positives = 123/317 (38%), Gaps = 37/317 (11%)
Query: 25 EQDDELYNPESEQDKNEKKGSKRKSDRME----STDTKRQKPSVHSRQLVSKPLSSSVSN 80
EQ++E + + EQ++ E++ + + +R + +T+R + +QL
Sbjct: 428 EQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
Query: 81 NKRIVSTKGKSATEYKNEEYQRSERNKR----------------LDADRKIRLSSSASRE 124
++ + + E + ++ +R + +R L +++++R RE
Sbjct: 488 WLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERRE 547
Query: 125 PY-KNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDH 183
K + EK ++R +R + + + E +RR R + +E + +
Sbjct: 548 QLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEV 607
Query: 184 ETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEE--------DAEEDEEVDEDGEEEEE- 234
E EQ E EE + + + EE EE + +E E EEEEE
Sbjct: 608 ERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEER 667
Query: 235 -------EEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRS 287
E EEE E+E EEE EQ K + + E+ +S ++ +
Sbjct: 668 LEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQE 727
Query: 288 GSGTDGSDEKKKERKRA 304
G E+K+ R+ +
Sbjct: 728 GQRRRQEQEEKRRRRES 744
Score = 56.6 bits (135), Expect = 8e-08
Identities = 60/285 (21%), Positives = 117/285 (41%), Gaps = 9/285 (3%)
Query: 26 QDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNKRIV 85
+++E E EQ E++ +R+ +R E K +K QL+ + +R
Sbjct: 931 REEEQLQQEEEQLLREEREKRRRQER-ERQYRKDKKLQQKEEQLLGEEPEKR-RRQEREK 988
Query: 86 STKGKSATEYKNEEYQRSERNKRL--DADRKIRLSSSASREP---YKNQPEKTCVRKRDP 140
+ + + + E+ R ER KR + +R+ R +E + + EK +++R+
Sbjct: 989 KYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERER 1048
Query: 141 ERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTEN 200
+ R + E+ L + R +R Q + + EE E E+ E
Sbjct: 1049 QYREEEELQQEEEQ--LLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQER 1106
Query: 201 EEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEE 260
E + EE+ + EE + EE E+ E + EEEE ++EEE+ E ++R ++E
Sbjct: 1107 ERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQEL 1166
Query: 261 GNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRAR 305
Y E + + R +E++ +R++ +
Sbjct: 1167 ERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRK 1211
Score = 56.2 bits (134), Expect = 1e-07
Identities = 49/259 (18%), Positives = 108/259 (41%), Gaps = 14/259 (5%)
Query: 22 EVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNN 81
E +Q L + + K E++ +++ +R E + + Q+ +QL +
Sbjct: 292 EEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQL 351
Query: 82 KRIVSTKGKSATEYKNEEYQRSE----RNKRLDADRKIRLSSSASREPYKNQPEKTCVRK 137
+R + + + +E +R E R ++L ++++R RE + ++ +R+
Sbjct: 352 RREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQ--LRR 409
Query: 138 RDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNN 197
RR + + R E +R + Q +E+ E + + + +
Sbjct: 410 EQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQ-EERRDWLKREEETERHE 468
Query: 198 TENEEEGVEEDVEEDE-------EVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEY 250
E ++ ++ D EE+ E EE E+ E ++ E+EE E+ + +EEEE
Sbjct: 469 QERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERL 528
Query: 251 EQDERDQKEEGNDYDTRSE 269
+Q R +++ + + R E
Sbjct: 529 QQRLRSEQQLRREQEERRE 547
Score = 56.2 bits (134), Expect = 1e-07
Identities = 58/252 (23%), Positives = 103/252 (40%), Gaps = 34/252 (13%)
Query: 17 DDILTEVPE-----QDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVS 71
+ +L E PE + ++ Y E E + E++ + + ++ + +RQ Q
Sbjct: 971 EQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEE 1030
Query: 72 KPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKN--- 128
+ L +R+ + +Y+ EE + E + L +R+ R R+ K
Sbjct: 1031 EQLLREEREKRRLQERE----RQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEEL 1086
Query: 129 QPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSS 188
Q E+ + + +PE+R RR R Q +EE +E E
Sbjct: 1087 QQEEEQLLREEPEKR-----------------RRQERERQCREEEELQQE-----EEQLL 1124
Query: 189 GSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEE 248
E+ E E + EE+ + EE + EE E+ E + EEEE ++EEE+
Sbjct: 1125 REEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLL 1184
Query: 249 EYEQDERDQKEE 260
EQ++R Q+ E
Sbjct: 1185 REEQEKRRQERE 1196
Score = 53.9 bits (128), Expect = 5e-07
Identities = 56/253 (22%), Positives = 102/253 (40%), Gaps = 5/253 (1%)
Query: 20 LTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVS 79
L E ++ +L E E+ + E++ KR+ E + ++ QL+ +
Sbjct: 895 LQEQLRKEQQLLQEEEEELQREER-EKRRRQEQERQYREEEQLQQEEEQLLREEREKRRR 953
Query: 80 NNKRIVSTKGKSATEYKNEEY--QRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRK 137
+ K K + K E+ + E+ +R + ++K R +E + E+ R+
Sbjct: 954 QERERQYRKDKKLQQ-KEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRR 1012
Query: 138 RDP-ERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGN 196
R ER+ + E L + R R Q + + EE E G E
Sbjct: 1013 RQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRR 1072
Query: 197 NTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERD 256
E E + +E+ + EE + EE E+ E + EEEE ++EEE+ E+++R
Sbjct: 1073 RQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRR 1132
Query: 257 QKEEGNDYDTRSE 269
++E Y E
Sbjct: 1133 RQELERQYREEEE 1145
Score = 52.4 bits (124), Expect = 1e-06
Identities = 64/322 (19%), Positives = 118/322 (36%), Gaps = 43/322 (13%)
Query: 22 EVPEQDDELYNPESE--QDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVS 79
E E+ D+L E E Q + +++ +R R++ + +R + Q + +
Sbjct: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEER 629
Query: 80 NNKRIVSTKGKSATEY---KNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVR 136
+ + S + + + + ++ +R +R KR + + ++ E + + E
Sbjct: 630 RQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEE 689
Query: 137 KRDPERRAKSPTPDGSERIGLEVDRRAS------RSSQSSKEEVNSEEYGSDHETGSSGS 190
+ R KS P ++ E D R S R + + EE E+
Sbjct: 690 QEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQ 749
Query: 191 SDEQGNNTENEEEG---------VEEDVE-------------EDEEVEEDAEEDEEVDED 228
+E+ + + EEE EE E E E + AEE ++ ++
Sbjct: 750 EEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQR 809
Query: 229 GEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSG 288
EEEE+E+ + E E+E + EE R A E + R
Sbjct: 810 FLPEEEEKEQRRRQRREREKELQ-----FLEEEEQLQRRERAQQLQEEEDGLQEDQERRR 864
Query: 289 SGTDGSDEK-----KKERKRAR 305
S D+K ++ERKR R
Sbjct: 865 SQEQRRDQKWRWQLEEERKRRR 886
Score = 52.4 bits (124), Expect = 1e-06
Identities = 60/281 (21%), Positives = 111/281 (39%), Gaps = 28/281 (9%)
Query: 6 REEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVH 65
R+E+D + + +L E EQ +L+ E ++ E++ R+ +R + R +
Sbjct: 1614 RQERDRKFREDEQLLQEREEQ--QLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFRE 1671
Query: 66 SRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEE----YQRSERNKRLDADRKIRLSSSA 121
QL+ + + +R + + + E Q ++ +R + +RK R
Sbjct: 1672 EEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQL 1731
Query: 122 SREP----------YKNQPEKTCVRKRDPERRAKSPTPDGS----ERIGLEVDRRASRSS 167
+E Y+ E+ +R E++ + D E++ E + + RS
Sbjct: 1732 RQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQ 1791
Query: 168 QSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEED----AEEDE 223
+S ++ E+ + E G EE+ E+ E+ E D AEE
Sbjct: 1792 ESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQF 1851
Query: 224 EVDEDGEEEEEEEEEEEEEEEEEEEE----YEQDERDQKEE 260
E EE+E +EEE++ +E E E R QKEE
Sbjct: 1852 ATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEE 1892
Score = 52.0 bits (123), Expect = 2e-06
Identities = 53/257 (20%), Positives = 106/257 (41%), Gaps = 32/257 (12%)
Query: 26 QDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNKRIV 85
+D +L + +S+QD G +++ DR + +Q+ + + L +
Sbjct: 1254 EDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEE---EQLEREEQKEAKRR 1310
Query: 86 STKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAK 145
K + + EE R E+ +R + DRK R +E + QP + ++RD + R +
Sbjct: 1311 DRKSQEEKQLLREE--REEKRRRQETDRKFREEEQLLQER-EEQPLRR--QERDRKFREE 1365
Query: 146 SPTPDGSERIGLEVDRRASRSSQSSK--------------EEVNSEEYGSDHETGSSGSS 191
R LE ++R R + K +++ + E S
Sbjct: 1366 ELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSR 1425
Query: 192 DEQGNNTENEEEGVEEDVEEDEEVEEDAE----------EDEEVDEDGEEEEEEEEEEEE 241
E+ EE+ V E + +EE+ + E+E++ ++ EE++ +E +
Sbjct: 1426 QERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDR 1485
Query: 242 EEEEEEEEYEQDERDQK 258
+ EEE++ + ERD+K
Sbjct: 1486 KFLEEEQQLRRQERDRK 1502
Score = 51.6 bits (122), Expect = 3e-06
Identities = 58/309 (18%), Positives = 123/309 (39%), Gaps = 42/309 (13%)
Query: 7 EEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEK----KGSKRKSDRMESTDTKRQKP 62
E ++ L + ++ E E+ ++ E E+ + ++ + +R R+ S R++
Sbjct: 483 ERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ 542
Query: 63 SVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSE--RNKRLDADRKIRLSSS 120
QL+ + + +R K + E +++ +R E R +RL +++ RL
Sbjct: 543 EERREQLLKREEEKRLEQERREQRLK-REQEERRDQLLKREEERRQQRLKREQEERLEQR 601
Query: 121 ASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYG 180
RE + ++ +R+ + + P + +++ ++ R Q +E+ E
Sbjct: 602 LKREEVERLEQE---ERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQR 658
Query: 181 SDHETGSSGSSDEQGNNTENEEEGVEEDVEEDE-------------------EVEEDAEE 221
E EQ E+EEE E+++ E+E E E DA +
Sbjct: 659 LKREEEEERL--EQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQ 716
Query: 222 DEEVDEDGEEEEEEEEEEEEE-----------EEEEEEEYEQDERDQKEEGNDYDTRSEA 270
+ ++E + +E+EE +EEE +Q E +Q+ + E
Sbjct: 717 SKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEK 776
Query: 271 SDSGSESVS 279
S+ G + +S
Sbjct: 777 SERGRQRLS 785
Score = 50.4 bits (119), Expect = 6e-06
Identities = 47/255 (18%), Positives = 104/255 (40%), Gaps = 11/255 (4%)
Query: 22 EVPEQDDELYNPESEQDKN---EKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSV 78
E+ +++++L E E+ + E++ + + + E R++P RQ + +
Sbjct: 1115 ELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEE 1174
Query: 79 S---NNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEK-TC 134
++++ + + + + +Y+ E +R ++ R S ++ +PEK
Sbjct: 1175 ELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENA 1234
Query: 135 VRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQ 194
VR + + + + LE + R SQ + + E+ D E
Sbjct: 1235 VR----DNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRD 1290
Query: 195 GNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDE 254
+ E E+ EE E + EE + + E+ EE+ +E + + EEE+ E++E
Sbjct: 1291 RHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREE 1350
Query: 255 RDQKEEGNDYDTRSE 269
+ + + D R E
Sbjct: 1351 QPLRRQERDRKFREE 1365
Score = 50.1 bits (118), Expect = 7e-06
Identities = 63/350 (18%), Positives = 135/350 (38%), Gaps = 37/350 (10%)
Query: 22 EVPEQDDELYNPESEQDKN---EKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSV 78
E+ +++++L E E + E++ K + + E R++P RQ
Sbjct: 1055 ELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQ---------- 1104
Query: 79 SNNKRIVSTKGKSATEYKNEEYQRSERNKRL--DADRKIRLSSSASREP---YKNQPEKT 133
+R + + + + E+ R ER KR + +R+ R +E + +PEK
Sbjct: 1105 ---ERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKR 1161
Query: 134 CVRKRDPERRAKSPTPDGSERIGLEVD--RRASRSSQSSKEEVNSEEYGSDHETGSSGSS 191
++ + + R + E++ E RR R Q +EE + S
Sbjct: 1162 RRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRS 1221
Query: 192 DEQGNNTENEEEGVEEDV--------EEDEEVEEDAEEDEEVDED-----GEEEEEEEEE 238
D + +E V ++ E+ ++E+ D + +D GE++E + E+
Sbjct: 1222 DLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQ 1281
Query: 239 EEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKK 298
E ++ + + ++E+ ++EE + R S + + R TD ++
Sbjct: 1282 ERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREE 1341
Query: 299 KERKRARGISPI-VFDRSGSSASESYAGSEKKHEKLSSSVRAVRKDQTSK 347
++ + R P+ +R E E+ + L R R+++ K
Sbjct: 1342 EQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERK 1391
Score = 50.1 bits (118), Expect = 7e-06
Identities = 57/297 (19%), Positives = 122/297 (41%), Gaps = 25/297 (8%)
Query: 22 EVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVS----KPLSSS 77
E+ +++++L E E+ + E++ R+ + ++ K++ R + ++
Sbjct: 1175 ELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENA 1234
Query: 78 VSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRK 137
V +NK V KG+ +NE++++ E ++ D + L + +++ ++ R+
Sbjct: 1235 VRDNK--VYCKGR-----ENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQE---RR 1284
Query: 138 RDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNS--EEYGSDHETGSSGSSDEQ- 194
R +R P + ER + +R R SQ K+ + EE ET +EQ
Sbjct: 1285 RWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQL 1344
Query: 195 --------GNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEE 246
E + + EE++ E+ + EE++ + E + +EE++ +E
Sbjct: 1345 LQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQER 1404
Query: 247 EEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKR 303
E++ QD + E +R E E R + + ++ER R
Sbjct: 1405 EQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHR 1461
Score = 49.3 bits (116), Expect = 1e-05
Identities = 57/297 (19%), Positives = 118/297 (39%), Gaps = 41/297 (13%)
Query: 6 REEKDGELNVLDDILTEVPEQD------DELYNPESEQDKNEKKGSKRKSDRMESTDTKR 59
R+E+ + + +L E EQ D + E +Q + +++ K + + S + +R
Sbjct: 1456 RQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPER 1515
Query: 60 ----QKPSVHSRQLVSKPLSSS--VSNNKRIVSTKGKSATEYKNEEYQRSERNK----RL 109
++ +H +Q K L + +R + +++ EE R ER + R
Sbjct: 1516 KFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQ 1575
Query: 110 DADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQS 169
+ DRK RL R + + E+ + RR +G +++ E DR+ Q
Sbjct: 1576 ERDRKFRLEEQKVR---RQEQERKFMEDEQQLRRQ-----EGQQQLRQERDRKFREDEQL 1627
Query: 170 SKEEVNSEEYGSDH--------------ETGSSGSSDEQGNNTENEE---EGVEEDVEED 212
+E + + + E D E E+ EG E+ +
Sbjct: 1628 LQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQ 1687
Query: 213 EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSE 269
E + EE++++ E + +EE++ +E E ++ ++E+ ++E + R E
Sbjct: 1688 ERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQE 1744
Score = 47.8 bits (112), Expect = 4e-05
Identities = 54/275 (19%), Positives = 114/275 (41%), Gaps = 25/275 (9%)
Query: 4 DSREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPS 63
+ R E+ E + + E+ ++ E E+ + ++ +++ +R E + Q+
Sbjct: 312 EERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEE 371
Query: 64 VHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASR 123
+QL ++ + + + E + Q+ R ++L ++++R R
Sbjct: 372 RREQQL----------RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 421
Query: 124 EPY--KNQPEKTCVRKRDPERRAKSPTPDGSERIG-LEVDRRASRSSQSS-KEEVNSEEY 179
E + Q E+ +K + ERR + + ER L+ + R Q K+++ ++
Sbjct: 422 EQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQE 481
Query: 180 GSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEE-------VDEDGEEE 232
E +E+ E E+ + + EE E +E+EE ++ E
Sbjct: 482 EERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRRE 541
Query: 233 EEEEEEE---EEEEEE-EEEEYEQDERDQKEEGND 263
+EE E+ EEE+ E+E EQ + ++EE D
Sbjct: 542 QEERREQLLKREEEKRLEQERREQRLKREQEERRD 576
Score = 47.4 bits (111), Expect = 5e-05
Identities = 57/293 (19%), Positives = 122/293 (41%), Gaps = 34/293 (11%)
Query: 5 SREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSK-------RKSDRMESTDT 57
SR+E+D + + + +V Q+ E E EQ ++G + RK E
Sbjct: 1573 SRQERDRKFRLEEQ---KVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQ 1629
Query: 58 KRQKPSVHSRQLVSKPLSSS--VSNNKRIVSTKGKSATEYKNEEYQRSERN----KRLDA 111
+R++ +H ++ K L + +R + +++ EE E +R +
Sbjct: 1630 EREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQER 1689
Query: 112 DRKIRLSSSASREPYKNQP---EKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQ 168
DRK R R + + E+ +R+++ ER+ + E++ E ++ R +
Sbjct: 1690 DRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFRE-----EEQLRQETEQEQLRRQE 1744
Query: 169 SSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAE--EDEEVD 226
++ + E+ + E + E E+ E + ++ E D + E+E++
Sbjct: 1745 RYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLR 1804
Query: 227 EDGEEEEEEEE--------EEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEAS 271
++ EE++ + EEE+ + EE+E+ + ERD++ + E S
Sbjct: 1805 QEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKS 1857
Score = 47.0 bits (110), Expect = 6e-05
Identities = 44/254 (17%), Positives = 101/254 (39%), Gaps = 17/254 (6%)
Query: 22 EVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNN 81
++ + D + E +Q +++ K + + + +R++ + Q + +
Sbjct: 1407 QLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREE 1466
Query: 82 KRIVSTKGKSATEYKNEE---YQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKR 138
++++ + + + + + ++ +R + DRK R S+EP + E+ R
Sbjct: 1467 EQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHR 1526
Query: 139 DPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEV----NSEEYGSDHETGSSGSSDEQ 194
+R R RR R + +EE E+ S E +EQ
Sbjct: 1527 QQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQ 1586
Query: 195 GNNTENEEEGVEEDVEE----------DEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEE 244
+ +E ED ++ +E + EDE++ ++ EE++ +E + +
Sbjct: 1587 KVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFL 1646
Query: 245 EEEEEYEQDERDQK 258
EEE + + ER+Q+
Sbjct: 1647 EEEPQLRRQEREQQ 1660
Score = 45.8 bits (107), Expect = 1e-04
Identities = 53/270 (19%), Positives = 108/270 (40%), Gaps = 20/270 (7%)
Query: 25 EQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNKRI 84
+Q + E +Q + +++G +R+ DR + Q Q +S+ +
Sbjct: 1527 QQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQ 1586
Query: 85 VSTKGKSATEYKNEEYQ----RSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDP 140
+ + ++ +E Q ++ R + DRK R +E + Q + ++RD
Sbjct: 1587 KVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHR---QERDR 1643
Query: 141 ERRAKSPTPDGSERIG-LEVDR-RASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNT 198
+ + P ER L DR R R + +E ++ ++Q
Sbjct: 1644 KFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQ 1703
Query: 199 ENEEEGVEEDVE-EDEEVEEDAEEDEEVDEDGEEEEE----------EEEEEEEEEEEEE 247
E E + ++E+ + +E+E E+E++ ++ E+E+ EEE+ E EE++
Sbjct: 1704 ERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQ 1763
Query: 248 EEYEQDERDQKEEGNDYDTRSEASDSGSES 277
++ +R +EE R E ES
Sbjct: 1764 LRRQERDRKFREEEQLRQEREEQQLRSQES 1793
Score = 45.4 bits (106), Expect = 2e-04
Identities = 44/240 (18%), Positives = 97/240 (40%), Gaps = 11/240 (4%)
Query: 25 EQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNKRI 84
E+++E +++ E++ + ++ + +R K + Q + S + + ++
Sbjct: 662 EEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLE--SEADARQSKV 719
Query: 85 VSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRA 144
S K + + +E + R R+ L ++ Q E+ R + +A
Sbjct: 720 YSRPRKQEGQRRRQEQEEKRRR------RESELQWQEEERAHRQQQEEEQRRDFTWQWQA 773
Query: 145 KSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEG 204
+ + G +R+ R R Q EE E E Q E E +
Sbjct: 774 EEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQF 833
Query: 205 VEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDY 264
+EE EE + E A++ +E +EDG +E++E +E+ +++ ++ +E ++ Y
Sbjct: 834 LEE--EEQLQRRERAQQLQE-EEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLY 890
Score = 45.4 bits (106), Expect = 2e-04
Identities = 48/254 (18%), Positives = 106/254 (41%), Gaps = 35/254 (13%)
Query: 25 EQDDELYNPESEQDKNEKKGSKRKSDRMEST-----DTKRQKPSVHSRQLVSK--PLSSS 77
EQ+++ ESE E++ + R+ E + ++ S RQ +S PL
Sbjct: 734 EQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQ 793
Query: 78 VSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRK 137
R + + EE + R +R + +++++ E+ +++
Sbjct: 794 RERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLE-----------EEEQLQR 842
Query: 138 RDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEE-----VNSEEYGSDHETGSSGSSD 192
R+ ++ + E GL+ D+ RS + +++ + E H + +
Sbjct: 843 RERAQQLQE------EEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQ 896
Query: 193 EQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEE------EEE 246
EQ + + EE+++ +E + +E E + E+ ++EEE+ EE +E
Sbjct: 897 EQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQER 956
Query: 247 EEEYEQDERDQKEE 260
E +Y +D++ Q++E
Sbjct: 957 ERQYRKDKKLQQKE 970
Score = 36.6 bits (83), Expect = 0.085
Identities = 21/57 (36%), Positives = 33/57 (57%), Gaps = 3/57 (5%)
Query: 674 RRSRPRERDRERER-DRPRDNRRDRERD--RGRDRERERERLCDRDRDRGERGRYRR 727
RR PR+R E E R R R+++ER+ G ++ ++ERL RDR R + +R+
Sbjct: 120 RRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQ 176
Score = 35.8 bits (81), Expect = 0.14
Identities = 18/76 (23%), Positives = 41/76 (53%), Gaps = 1/76 (1%)
Query: 186 GSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDED-GEEEEEEEEEEEEEEE 244
G + DE+ + +E + +D ++E+ D +++E+ G+ ++ +E+E E
Sbjct: 90 GQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELA 149
Query: 245 EEEEEYEQDERDQKEE 260
E EE+ E+ ER ++ +
Sbjct: 150 EGEEQSEKQERLEQRD 165
Score = 34.7 bits (78), Expect = 0.32
Identities = 26/113 (23%), Positives = 45/113 (39%), Gaps = 10/113 (8%)
Query: 180 GSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEE 239
G D E + E +EE D ++EE+ + +E E E EE
Sbjct: 94 GLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEE 153
Query: 240 EEEEEEEEEEYEQDERD-----QKEEGNDYDTRSEASD-----SGSESVSFTD 282
+ E++E E+ ++ RD Q++E + + R + G E+ F D
Sbjct: 154 QSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPD 206
Score = 34.7 bits (78), Expect = 0.32
Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 6/91 (6%)
Query: 640 HPVPHEARYRDKRVHDYDMRVDDFLRR---TQAVVSGRRSRPRERDRERERDRPRDNRRD 696
H HE R++R+ D+L+R T+ RR + +RD+E ER R+
Sbjct: 434 HEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEER---RERWLK 490
Query: 697 RERDRGRDRERERERLCDRDRDRGERGRYRR 727
E + R+++ RE+ R+++ R +R
Sbjct: 491 LEEEERREQQERREQQLRREQEERREQRLKR 521
Score = 33.9 bits (76), Expect = 0.55
Identities = 28/121 (23%), Positives = 50/121 (41%), Gaps = 16/121 (13%)
Query: 156 GLEVDRRASRSSQSSK-EEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEE 214
GL+ ++RA + S ++ EE E +E G + + E ++ E EE
Sbjct: 94 GLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEE 153
Query: 215 VEEDAEEDEEVD---------------EDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKE 259
E E E+ D ++ EE EEE+ + + E EE+ +E+ ++
Sbjct: 154 QSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRR 213
Query: 260 E 260
E
Sbjct: 214 E 214
Score = 33.5 bits (75), Expect = 0.72
Identities = 18/65 (27%), Positives = 37/65 (56%), Gaps = 2/65 (3%)
Query: 658 MRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDR 717
+R + LRR Q RR + ER ++ER ++ RR+++ R ++ RE++ +++
Sbjct: 300 LRREQQLRRKQE--EERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEE 357
Query: 718 DRGER 722
+R E+
Sbjct: 358 ERREQ 362
Score = 33.1 bits (74), Expect = 0.94
Identities = 18/80 (22%), Positives = 45/80 (56%), Gaps = 6/80 (7%)
Query: 187 SSGSSDEQGNNTENEEEGVEEDVEEDEEVE---EDAEEDEEVDEDGEEEEEEEEEEE--- 240
++G +E+ + +E +++ +E+++ D + +EE + ++ +E+E E
Sbjct: 92 ATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEG 151
Query: 241 EEEEEEEEEYEQDERDQKEE 260
EE+ E++E EQ +R +++E
Sbjct: 152 EEQSEKQERLEQRDRQRRDE 171
Score = 33.1 bits (74), Expect = 0.94
Identities = 22/81 (27%), Positives = 43/81 (53%), Gaps = 10/81 (12%)
Query: 649 RDKRVHDYDMRVDD----FLRRTQAVVSGRRSRP--RERDRERERDRPRDNRRDRERDRG 702
RD++ + ++R + FL Q + +R R +E + R ++R + R+DR+R
Sbjct: 1499 RDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFR 1558
Query: 703 RD----RERERERLCDRDRDR 719
+ +ERE ++L ++RDR
Sbjct: 1559 EEEQLRQEREEQQLSRQERDR 1579
Score = 32.7 bits (73), Expect = 1.2
Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 5/83 (6%)
Query: 645 EARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRD 704
E R + +R + R + LRR Q RR + R++E ER R + RR++E +R R+
Sbjct: 320 ERREQQERREQQEERREQQLRREQ---EERREQQLRREQEEER-REQQLRREQEEER-RE 374
Query: 705 RERERERLCDRDRDRGERGRYRR 727
++ RE+ R++ + RR
Sbjct: 375 QQLRREQQLRREQQLRREQQLRR 397
Score = 32.0 bits (71), Expect = 2.1
Identities = 22/82 (26%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Query: 645 EARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRD 704
E+ +D+R + R + R+ + G+R R + +++ERE + +ER RD
Sbjct: 107 ESLLQDRRQEEDQRRFEPRDRQLEEE-PGQRRRQKRQEQERELAEGEEQSEKQERLEQRD 165
Query: 705 RERERERLCDRDRDRGERGRYR 726
R+R E L + ++ ER R
Sbjct: 166 RQRRDEELWRQRQEWQEREERR 187
Score = 31.6 bits (70), Expect = 2.7
Identities = 20/69 (28%), Positives = 36/69 (52%), Gaps = 8/69 (11%)
Query: 664 LRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRG-----RDRERERERLCDRDRD 718
LRR Q + RR + ER ++E R + RR+++ +R R++E RE+ R+++
Sbjct: 300 LRREQQL---RRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQE 356
Query: 719 RGERGRYRR 727
R + R
Sbjct: 357 EERREQQLR 365
Score = 31.6 bits (70), Expect = 2.7
Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 6/60 (10%)
Query: 655 DYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRD---RERERER 711
+ +R + LRR Q + RR + ER ++ R+ R RE++ RD RE E ER
Sbjct: 410 EQQLRREQQLRREQQL---RREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETER 466
Score = 31.6 bits (70), Expect = 2.7
Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 4/74 (5%)
Query: 655 DYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRD---RERDRGRDRERERER 711
+ +R + LRR Q + +ER RE+ R ++ RRD RE + R + R++
Sbjct: 416 EQQLRREQQLRREQEEERHEQKHEQER-REQRLKREQEERRDWLKREEETERHEQERRKQ 474
Query: 712 LCDRDRDRGERGRY 725
RD++ R R+
Sbjct: 475 QLKRDQEEERRERW 488
Score = 30.8 bits (68), Expect = 4.6
Identities = 21/81 (25%), Positives = 40/81 (49%), Gaps = 3/81 (3%)
Query: 645 EARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERD---RERERDRPRDNRRDRERDR 701
E RD +V+ + F + + + R+S+ + ++ERDR ++ RR ++RDR
Sbjct: 1232 ENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDR 1291
Query: 702 GRDRERERERLCDRDRDRGER 722
E + ER ++ R +R
Sbjct: 1292 HFPEEEQLEREEQKEAKRRDR 1312
Score = 30.8 bits (68), Expect = 4.6
Identities = 20/79 (25%), Positives = 40/79 (50%), Gaps = 2/79 (2%)
Query: 643 PHEARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRG 702
P + RD++ + ++R + R+ R + RER +E + R R+++ +
Sbjct: 1352 PLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQD 1411
Query: 703 RDRE--RERERLCDRDRDR 719
RDR+ E ++L ++RDR
Sbjct: 1412 RDRKFREEEQQLSRQERDR 1430
Score = 30.4 bits (67), Expect = 6.1
Identities = 21/83 (25%), Positives = 37/83 (44%)
Query: 645 EARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRD 704
E R + R + R + LRR Q + RE+ RE+ R+ + RE+ R+
Sbjct: 345 ERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRRE 404
Query: 705 RERERERLCDRDRDRGERGRYRR 727
++ RE+ R++ + RR
Sbjct: 405 QQLRREQQLRREQQLRREQQLRR 427
Score = 30.4 bits (67), Expect = 6.1
Identities = 20/78 (25%), Positives = 41/78 (52%), Gaps = 1/78 (1%)
Query: 647 RYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRE 706
R +++ + +R + LRR Q + ++ R RE+ RE+ R+ + RE+ R+++
Sbjct: 366 REQEEERREQQLRREQQLRREQQLRREQQLR-REQQLRREQQLRREQQLRREQQLRREQQ 424
Query: 707 RERERLCDRDRDRGERGR 724
RE+ +R + E+ R
Sbjct: 425 LRREQEEERHEQKHEQER 442
Score = 30.0 bits (66), Expect = 7.9
Identities = 23/85 (27%), Positives = 37/85 (43%), Gaps = 4/85 (4%)
Query: 641 PVPHEARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERD 700
P E R R R + R FL + RR R R+RE+E + + + R+
Sbjct: 788 PPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQR---REREKELQFLEEEEQLQRRE 844
Query: 701 RGRDRERERERLC-DRDRDRGERGR 724
R + + E + L D++R R + R
Sbjct: 845 RAQQLQEEEDGLQEDQERRRSQEQR 869
Score = 30.0 bits (66), Expect = 7.9
Identities = 26/92 (28%), Positives = 38/92 (41%), Gaps = 13/92 (14%)
Query: 649 RDKRVHDYDMRVD----------DFLRRTQAVVSGRRS---RPRERDRERERDRPRDNRR 695
R +R D D R D + +R + GR + R E + R+R +D +
Sbjct: 1210 RKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQH 1269
Query: 696 DRERDRGRDRERERERLCDRDRDRGERGRYRR 727
+ RDRE+ER R RDR E + R
Sbjct: 1270 LLGEQQERDREQERRRWQQRDRHFPEEEQLER 1301
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.129 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,861,822
Number of Sequences: 37866
Number of extensions: 2074750
Number of successful extensions: 111152
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1523
Number of HSP's successfully gapped in prelim test: 1076
Number of HSP's that attempted gapping in prelim test: 21853
Number of HSP's gapped (non-prelim): 29433
length of query: 727
length of database: 18,247,518
effective HSP length: 110
effective length of query: 617
effective length of database: 14,082,258
effective search space: 8688753186
effective search space used: 8688753186
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.