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Search of human proteins with 71834861
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|71834861 Rho GTPase activating protein 5 isoform b [Homo
sapiens]
(1501 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapi... 3044 0.0
gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapi... 3039 0.0
gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo ... 1469 0.0
gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens] 128 4e-29
gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens] 128 4e-29
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa... 122 2e-27
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap... 122 2e-27
gi|4757980 beta chimerin isoform 2 [Homo sapiens] 122 3e-27
gi|91106928 beta chimerin isoform 1 [Homo sapiens] 122 3e-27
gi|188497642 ARHGAP15 [Homo sapiens] 115 2e-25
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] 108 3e-23
gi|229094128 active breakpoint cluster region-related protein i... 106 2e-22
gi|38679957 active breakpoint cluster region-related protein is... 106 2e-22
gi|38679954 active breakpoint cluster region-related protein is... 106 2e-22
gi|5803145 ralA binding protein 1 [Homo sapiens] 105 4e-22
gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens] 102 2e-21
gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens] 102 2e-21
gi|224458284 Rho GTPase activating protein 23 [Homo sapiens] 102 3e-21
gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa... 100 8e-21
gi|54860079 nadrin isoform 1 [Homo sapiens] 100 8e-21
gi|54860105 nadrin isoform 2 [Homo sapiens] 100 8e-21
gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo sa... 100 1e-20
gi|50843948 Rho GTPase activating protein 10 [Homo sapiens] 100 1e-20
gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sa... 100 1e-20
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] 100 1e-20
gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b ... 99 3e-20
gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a ... 99 3e-20
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens] 99 3e-20
gi|156071465 Rho GTPase activating protein 4 [Homo sapiens] 98 5e-20
gi|4505507 oligophrenin 1 [Homo sapiens] 97 1e-19
>gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapiens]
Length = 1501
Score = 3044 bits (7892), Expect = 0.0
Identities = 1501/1501 (100%), Positives = 1501/1501 (100%)
Query: 1 MMAKNKEPRPPSYTISIVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTI 60
MMAKNKEPRPPSYTISIVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTI
Sbjct: 1 MMAKNKEPRPPSYTISIVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTI 60
Query: 61 DFGGRVVNNDHFLYWGDIIQNSEDGVECKIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAA 120
DFGGRVVNNDHFLYWGDIIQNSEDGVECKIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAA
Sbjct: 61 DFGGRVVNNDHFLYWGDIIQNSEDGVECKIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAA 120
Query: 121 ASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFV 180
ASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFV
Sbjct: 121 ASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFV 180
Query: 181 NNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFT 240
NNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFT
Sbjct: 181 NNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFT 240
Query: 241 ALVQMLDKTRSKPKIIPYLDAYKTQRQLVVTATDKFEKLVQTVRDYHATWKTVSNKLKNH 300
ALVQMLDKTRSKPKIIPYLDAYKTQRQLVVTATDKFEKLVQTVRDYHATWKTVSNKLKNH
Sbjct: 241 ALVQMLDKTRSKPKIIPYLDAYKTQRQLVVTATDKFEKLVQTVRDYHATWKTVSNKLKNH 300
Query: 301 PDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYINTLPRAFNTLLPNLEEIEHLN 360
PDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYINTLPRAFNTLLPNLEEIEHLN
Sbjct: 301 PDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYINTLPRAFNTLLPNLEEIEHLN 360
Query: 361 WSEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQH 420
WSEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQH
Sbjct: 361 WSEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQH 420
Query: 421 LISEKRRVEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAYKYITEADSKEVYGRHQR 480
LISEKRRVEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAYKYITEADSKEVYGRHQR
Sbjct: 421 LISEKRRVEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAYKYITEADSKEVYGRHQR 480
Query: 481 EIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRES 540
EIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRES
Sbjct: 481 EIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRES 540
Query: 541 LLLKHIGFVYHPTKETCLSGQNCTDIKVEQLLASSLLQLDHGRLRLYHDSTNIDKVNLFI 600
LLLKHIGFVYHPTKETCLSGQNCTDIKVEQLLASSLLQLDHGRLRLYHDSTNIDKVNLFI
Sbjct: 541 LLLKHIGFVYHPTKETCLSGQNCTDIKVEQLLASSLLQLDHGRLRLYHDSTNIDKVNLFI 600
Query: 601 LGKDGLAQELANEIRTQSTDDEYALDGKIYELDLRPVDAKSPYFLSQLWTAAFKPHGCFC 660
LGKDGLAQELANEIRTQSTDDEYALDGKIYELDLRPVDAKSPYFLSQLWTAAFKPHGCFC
Sbjct: 601 LGKDGLAQELANEIRTQSTDDEYALDGKIYELDLRPVDAKSPYFLSQLWTAAFKPHGCFC 660
Query: 661 VFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQ 720
VFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQ
Sbjct: 661 VFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQ 720
Query: 721 LANKLQCPFVDVPAGTYPRKFNETQIKQALRGVLESVKHNLDVVSPIPANKDLSEADLRI 780
LANKLQCPFVDVPAGTYPRKFNETQIKQALRGVLESVKHNLDVVSPIPANKDLSEADLRI
Sbjct: 721 LANKLQCPFVDVPAGTYPRKFNETQIKQALRGVLESVKHNLDVVSPIPANKDLSEADLRI 780
Query: 781 VMCAMCGDPFSVDLILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITILSYHSSI 840
VMCAMCGDPFSVDLILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITILSYHSSI
Sbjct: 781 VMCAMCGDPFSVDLILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITILSYHSSI 840
Query: 841 GVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKEL 900
GVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKEL
Sbjct: 841 GVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKEL 900
Query: 901 MTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDNTRESTHQ 960
MTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDNTRESTHQ
Sbjct: 901 MTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDNTRESTHQ 960
Query: 961 SEDVFLPSPRDCFPYNNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRLDLEGNEYP 1020
SEDVFLPSPRDCFPYNNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRLDLEGNEYP
Sbjct: 961 SEDVFLPSPRDCFPYNNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRLDLEGNEYP 1020
Query: 1021 IHSTPNCHDHERNHKVPPPIKPKPVVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLA 1080
IHSTPNCHDHERNHKVPPPIKPKPVVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLA
Sbjct: 1021 IHSTPNCHDHERNHKVPPPIKPKPVVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLA 1080
Query: 1081 HPEDMDPSDNYAEPIDTIFKQKGYSDEIYVVPDDSQNRIKIRNSFVNNTQGDEENGFSDR 1140
HPEDMDPSDNYAEPIDTIFKQKGYSDEIYVVPDDSQNRIKIRNSFVNNTQGDEENGFSDR
Sbjct: 1081 HPEDMDPSDNYAEPIDTIFKQKGYSDEIYVVPDDSQNRIKIRNSFVNNTQGDEENGFSDR 1140
Query: 1141 TSKSHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFTTSKTKRKGRHRGSEEDPL 1200
TSKSHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFTTSKTKRKGRHRGSEEDPL
Sbjct: 1141 TSKSHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFTTSKTKRKGRHRGSEEDPL 1200
Query: 1201 LSPVETWKGGIDNPAITSDQELDDKKMKKKTHKVKEDKKKKKTKNFNPPTRRNWESNYFG 1260
LSPVETWKGGIDNPAITSDQELDDKKMKKKTHKVKEDKKKKKTKNFNPPTRRNWESNYFG
Sbjct: 1201 LSPVETWKGGIDNPAITSDQELDDKKMKKKTHKVKEDKKKKKTKNFNPPTRRNWESNYFG 1260
Query: 1261 MPLQDLVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLV 1320
MPLQDLVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLV
Sbjct: 1261 MPLQDLVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLV 1320
Query: 1321 SMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVN 1380
SMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVN
Sbjct: 1321 SMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVN 1380
Query: 1381 YDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETF 1440
YDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETF
Sbjct: 1381 YDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETF 1440
Query: 1441 IQQCQFFFYNGEIVETTNIVAPPPPSNPGQLVEPMVPLQLPPPLQPQLIQPQLQTDPLGI 1500
IQQCQFFFYNGEIVETTNIVAPPPPSNPGQLVEPMVPLQLPPPLQPQLIQPQLQTDPLGI
Sbjct: 1441 IQQCQFFFYNGEIVETTNIVAPPPPSNPGQLVEPMVPLQLPPPLQPQLIQPQLQTDPLGI 1500
Query: 1501 I 1501
I
Sbjct: 1501 I 1501
>gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapiens]
Length = 1502
Score = 3039 bits (7880), Expect = 0.0
Identities = 1501/1502 (99%), Positives = 1501/1502 (99%), Gaps = 1/1502 (0%)
Query: 1 MMAKNKEPRPPSYTISIVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTI 60
MMAKNKEPRPPSYTISIVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTI
Sbjct: 1 MMAKNKEPRPPSYTISIVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTI 60
Query: 61 DFGGRVVNNDHFLYWGDIIQNSEDGVECKIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAA 120
DFGGRVVNNDHFLYWGDIIQNSEDGVECKIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAA
Sbjct: 61 DFGGRVVNNDHFLYWGDIIQNSEDGVECKIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAA 120
Query: 121 ASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFV 180
ASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFV
Sbjct: 121 ASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFV 180
Query: 181 NNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFT 240
NNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFT
Sbjct: 181 NNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFT 240
Query: 241 ALVQMLDKTRSKPKIIPYLDAYKTQRQLVVTATDKFEKLVQTVRDYHATWKTVSNKLKNH 300
ALVQMLDKTRSKPKIIPYLDAYKTQRQLVVTATDKFEKLVQTVRDYHATWKTVSNKLKNH
Sbjct: 241 ALVQMLDKTRSKPKIIPYLDAYKTQRQLVVTATDKFEKLVQTVRDYHATWKTVSNKLKNH 300
Query: 301 PDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYINTLPRAFNTLLPNLEEIEHLN 360
PDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYINTLPRAFNTLLPNLEEIEHLN
Sbjct: 301 PDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYINTLPRAFNTLLPNLEEIEHLN 360
Query: 361 WSEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQH 420
WSEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQH
Sbjct: 361 WSEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQH 420
Query: 421 LISEKRRVEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAYKYITEADSKEVYGRHQR 480
LISEKRRVEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAYKYITEADSKEVYGRHQR
Sbjct: 421 LISEKRRVEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAYKYITEADSKEVYGRHQR 480
Query: 481 EIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRES 540
EIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRES
Sbjct: 481 EIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRES 540
Query: 541 LLLKHIGFVYHPTKETCLSGQNCTDIKVEQLLASSLLQLDHGRLRLYHDSTNIDKVNLFI 600
LLLKHIGFVYHPTKETCLSGQNCTDIKVEQLLASSLLQLDHGRLRLYHDSTNIDKVNLFI
Sbjct: 541 LLLKHIGFVYHPTKETCLSGQNCTDIKVEQLLASSLLQLDHGRLRLYHDSTNIDKVNLFI 600
Query: 601 LGKDGLAQELANEIRTQSTDDEYALDGKIYELDLRPVDAKSPYFLSQLWTAAFKPHGCFC 660
LGKDGLAQELANEIRTQSTDDEYALDGKIYELDLRPVDAKSPYFLSQLWTAAFKPHGCFC
Sbjct: 601 LGKDGLAQELANEIRTQSTDDEYALDGKIYELDLRPVDAKSPYFLSQLWTAAFKPHGCFC 660
Query: 661 VFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQ 720
VFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQ
Sbjct: 661 VFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQ 720
Query: 721 LANKLQCPFVDVPAGTYPRKFNETQIKQALRGVLESVKHNLDVVSPIPANKDLSEADLRI 780
LANKLQCPFVDVPAGTYPRKFNETQIKQALRGVLESVKHNLDVVSPIPANKDLSEADLRI
Sbjct: 721 LANKLQCPFVDVPAGTYPRKFNETQIKQALRGVLESVKHNLDVVSPIPANKDLSEADLRI 780
Query: 781 VMCAMCGDPFSVDLILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITILSYHSSI 840
VMCAMCGDPFSVDLILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITILSYHSSI
Sbjct: 781 VMCAMCGDPFSVDLILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITILSYHSSI 840
Query: 841 GVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKEL 900
GVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKEL
Sbjct: 841 GVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKEL 900
Query: 901 MTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDNTRESTHQ 960
MTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDNTRESTHQ
Sbjct: 901 MTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDNTRESTHQ 960
Query: 961 SEDVFLPSPRDCFPYNNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRLDLEGNEYP 1020
SEDVFLPSPRDCFPYNNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRLDLEGNEYP
Sbjct: 961 SEDVFLPSPRDCFPYNNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRLDLEGNEYP 1020
Query: 1021 IHSTPNCHDHERNHKVPPPIKPKPVVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLA 1080
IHSTPNCHDHERNHKVPPPIKPKPVVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLA
Sbjct: 1021 IHSTPNCHDHERNHKVPPPIKPKPVVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLA 1080
Query: 1081 HPEDMDPSDNYAEPIDTIFKQKGYSDEIYVVPDDSQNRIKIRNSFVNNTQGDEENGFSDR 1140
HPEDMDPSDNYAEPIDTIFKQKGYSDEIYVVPDDSQNRIKIRNSFVNNTQGDEENGFSDR
Sbjct: 1081 HPEDMDPSDNYAEPIDTIFKQKGYSDEIYVVPDDSQNRIKIRNSFVNNTQGDEENGFSDR 1140
Query: 1141 TSKSHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFTTSKTKRKGRHRGSEEDPL 1200
TSKSHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFTTSKTKRKGRHRGSEEDPL
Sbjct: 1141 TSKSHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFTTSKTKRKGRHRGSEEDPL 1200
Query: 1201 LSPVETWKGGIDNPAITSDQELDDKKMKKKTHKVKEDKK-KKKTKNFNPPTRRNWESNYF 1259
LSPVETWKGGIDNPAITSDQELDDKKMKKKTHKVKEDKK KKKTKNFNPPTRRNWESNYF
Sbjct: 1201 LSPVETWKGGIDNPAITSDQELDDKKMKKKTHKVKEDKKQKKKTKNFNPPTRRNWESNYF 1260
Query: 1260 GMPLQDLVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINL 1319
GMPLQDLVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINL
Sbjct: 1261 GMPLQDLVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINL 1320
Query: 1320 VSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPV 1379
VSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPV
Sbjct: 1321 VSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPV 1380
Query: 1380 NYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVET 1439
NYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVET
Sbjct: 1381 NYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVET 1440
Query: 1440 FIQQCQFFFYNGEIVETTNIVAPPPPSNPGQLVEPMVPLQLPPPLQPQLIQPQLQTDPLG 1499
FIQQCQFFFYNGEIVETTNIVAPPPPSNPGQLVEPMVPLQLPPPLQPQLIQPQLQTDPLG
Sbjct: 1441 FIQQCQFFFYNGEIVETTNIVAPPPPSNPGQLVEPMVPLQLPPPLQPQLIQPQLQTDPLG 1500
Query: 1500 II 1501
II
Sbjct: 1501 II 1502
>gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo
sapiens]
Length = 1499
Score = 1469 bits (3803), Expect = 0.0
Identities = 770/1527 (50%), Positives = 1044/1527 (68%), Gaps = 63/1527 (4%)
Query: 1 MMAKNKEPRPPSYTISIVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTI 60
MMA+ ++ R P+Y IS+VGLSGTEK+KG CG+GKSCLCNRFVR ADE++ +HTSVLST
Sbjct: 2 MMARKQDVRIPTYNISVVGLSGTEKEKGQCGIGKSCLCNRFVRPSADEFHLDHTSVLSTS 61
Query: 61 DFGGRVVNNDHFLYWGDIIQNSEDGVECKIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAA 120
DFGGRVVNNDHFLYWG++ ++ ED VECK+H++EQTEFIDDQTF PHRST LQPYIKRAA
Sbjct: 62 DFGGRVVNNDHFLYWGEVSRSLEDCVECKMHIVEQTEFIDDQTFQPHRSTALQPYIKRAA 121
Query: 121 ASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFV 180
A+KL SAEKLMY CTDQLGLEQDFEQKQMP+GKL VDGFLL IDVS+G NR FDDQLKFV
Sbjct: 122 ATKLASAEKLMYFCTDQLGLEQDFEQKQMPDGKLLVDGFLLGIDVSRGMNRNFDDQLKFV 181
Query: 181 NNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFT 240
+NL+ QL+K+KKP+++ TKCDE V+ Y+R+ FA +KKNL VVETSAR NVN++ F+
Sbjct: 182 SNLYNQLAKTKKPIVVVLTKCDEGVERYIRDAHTFALSKKNLQVVETSARSNVNVDLAFS 241
Query: 241 ALVQMLDKTRSKPKIIPYLDAYKTQRQLVVTATDKFEKLV-QTVRDYHATWKTVSNKLKN 299
LVQ++DK+R K KIIPY +A K Q Q + TA DK+E LV + V++++ W +VS K++
Sbjct: 242 TLVQLIDKSRGKTKIIPYFEALKQQSQQIATAKDKYEWLVSRIVKNHNENWLSVSRKMQA 301
Query: 300 HPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYINTLPRAFNTLLPNLEEIEHL 359
P+Y++Y+ LEGT+KA+ F +HI +LK EHI +RR+ Y+ LP AF L+PNL+EI+HL
Sbjct: 302 SPEYQDYVYLEGTQKAKKLFLQHIHRLKHEHIERRRKLYLAALPLAFEALIPNLDEIDHL 361
Query: 360 NWSEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQ 419
+ +A KL+E + +F FVVLE+TPWD T HID + + RIPFDL+ T+ AE++Y+ H++
Sbjct: 362 SCIKAKKLLETKPEFLKWFVVLEETPWDATSHIDNMENERIPFDLMDTVPAEQLYEAHLE 421
Query: 420 HLISEKRRVEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAYKYITEADSKEVYGRHQ 479
L +E++RVEM+ FK+ LE FI+PG+PWEE F+M ++ Y+++ E+ ++YG+HQ
Sbjct: 422 KLRNERKRVEMRRAFKENLETSPFITPGKPWEEARSFIMNEDFYQWLEESVYMDIYGKHQ 481
Query: 480 REIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRE 539
++I++KAKEEFQE+L E+SELFY+L+L+A PS +KM I VL EE R+KALQKL +R+
Sbjct: 482 KQIIDKAKEEFQELLLEYSELFYELELDAKPSKEKMGVIQDVLGEEQRFKALQKLQAERD 541
Query: 540 SLLLKHIGFVYHPTKETCLSGQNCTDIKVEQLLASSLLQLDHGRLRLYHDSTNIDKVNLF 599
+L+LKHI FVYHPTKETC S C D K+E L++S ++ + NID++NL
Sbjct: 542 ALILKHIHFVYHPTKETCPSCPACVDAKIEHLISSRFIRPSDRNQKNSLSDPNIDRINLV 601
Query: 600 ILGKDGLAQELANEIRTQST-DDEYALDGKIYELDLRPVDAKSPYFLSQLWTAAFKPHGC 658
ILGKDGLA+ELANEIR T DD+Y +DGK+YEL LRP++ ++ T F+PHGC
Sbjct: 602 ILGKDGLARELANEIRALCTNDDKYVIDGKMYELSLRPIEGNVRLPVNSFQTPTFQPHGC 661
Query: 659 FCVFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQR-DSISKNLPILRHQ 717
C++NS ESLS++ E I K R E++ R+D ++ +LP TLIL N+R D+ + L L Q
Sbjct: 662 LCLYNSKESLSYVVESIEKSR-ESTLGRRDNHLVHLPLTLILVNKRGDTSGETLHSLIQQ 720
Query: 718 GQQLANKLQCPFVDVPAGT---YPRKFNETQIKQALRGVLESVKHNLDVVSPIPANKDLS 774
GQQ+A+KLQC F+D PA Y R NE QI Q L+G+L+S K NL++VS + KDL+
Sbjct: 721 GQQIASKLQCVFLD-PASAGIGYGRNINEKQISQVLKGLLDS-KRNLNLVSSTASIKDLA 778
Query: 775 EADLRIVMCAMCGDPFSVDLILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITIL 834
+ DLRIVMC MCGDPFS D IL P L S +C ++ G NNS++L+ IG ++RI++++L
Sbjct: 779 DVDLRIVMCLMCGDPFSADDILFPVLQSQTCKSSHCGSNNSVLLELPIGLHKKRIELSVL 838
Query: 835 SYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFEN 894
SYHSS +RK LVHGYI+ YSAKRKAS+ MLRAFL EVQD IP+QLVA+TD D +N
Sbjct: 839 SYHSSFSIRKSRLVHGYIVFYSAKRKASLAMLRAFLCEVQDIIPIQLVALTDGAVDVLDN 898
Query: 895 EAIKELMTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDNT 954
+ +E +TEGE IA EI +FT++ SQ + E+F FF DV+EKKN+IE +++ DN
Sbjct: 899 DLSREQLTEGEEIAQEIDGRFTSI-PCSQPQHKLEIFHPFFKDVVEKKNIIEATHMYDNA 957
Query: 955 RESTHQSEDVFLPSPRDCFPY--NNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRL 1012
E+ +E+VF SPR P +N DS++D E P YS +D L D S+ +
Sbjct: 958 AEACSTTEEVF-NSPRAGSPLCNSNLQDSEEDIE--PSYSLFREDTSLPSLSKDHSKLSM 1014
Query: 1013 DLEGNEYPIHSTPNCHDHERNHKVPPPIKPKPVVPKTNVKKLDPNLLKTIEAGIGKNPRK 1072
+LEGN+ N + + N+KVPPP+KPKP V + K D L ++ G RK
Sbjct: 1015 ELEGNDGLSFIMSN-FESKLNNKVPPPVKPKPPV-HFEITKGD---LSYLDQGHRDGQRK 1069
Query: 1073 QTSRVPLAHPEDMDPSDNYAEPIDTIFKQKGYSDEIYVVPDDSQNR--IKIRNSFVNNTQ 1130
S P + DPSD YAEP+D + K + + IY VP DS I IRN +N Q
Sbjct: 1070 SVSSSPWLPQDGFDPSD-YAEPMDAVVKPRNEEENIYSVPHDSTQGKIITIRN--INKAQ 1126
Query: 1131 GDEENGFSDRTSKSHGERRPSKYKYKSKTLFSKAK-------SYYRRTHSDASDDEAFTT 1183
+ SD + R K SK + + + + YR + S SDDE
Sbjct: 1127 SNGSGNGSDSEMDTSSLERGRKVSIVSKPVLYRTRCTRLGRFASYRTSFSVGSDDELGPI 1186
Query: 1184 SKTKRKGRHRGSEEDPLLSPVETWKGGIDNPAITSDQELDDKKMKKKTHKVKEDKKKKKT 1243
K + +G + D + P ET +D + + ++ + KK K
Sbjct: 1187 RKKEEDQASQGYKGDNAVIPYET---------------DEDPRRRNILRSLRRNTKKPKP 1231
Query: 1244 KNFNPPTRRNWESNYFGMPLQDLVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTD 1303
K T+ WESNYFG+PL +VT EKPIP+F+E+C+E+IE TGL TEG+YRVSGNK++
Sbjct: 1232 KPRPSITKATWESNYFGVPLTTVVTPEKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSE 1291
Query: 1304 QDNIQKQFDQDHNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKT 1363
+++Q+QFDQDHN++L + TVN VAGA+K+FF++LPDPL+PY++ +L+EA KI D+
Sbjct: 1292 MESLQRQFDQDHNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDRE 1351
Query: 1364 ERLHALKEIVKKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFEN 1423
++LHALKE++KKF N++VF+YVI+HLN+VS +K+NLMT++NLSICFWPTLMRPDF
Sbjct: 1352 QKLHALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMRPDFST 1411
Query: 1424 REFLSTTKIHQSVVETFIQQCQFFFYNGEIVETTNIVAPPPPSNPGQLV----------E 1473
+ L+ T+ +Q+++E FIQQC FFFYN I E P PS V +
Sbjct: 1412 MDALTATRTYQTIIELFIQQCPFFFYNRPITEPPG-ARPSSPSAVASTVPFLTSTPVTSQ 1470
Query: 1474 PMVPLQLPP----PLQPQLIQPQLQTD 1496
P P PP P+QP L+ QLQ +
Sbjct: 1471 PSPPQSPPPTPQSPMQP-LLPSQLQAE 1496
>gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]
Length = 459
Score = 128 bits (322), Expect = 4e-29
Identities = 71/178 (39%), Positives = 104/178 (58%), Gaps = 3/178 (1%)
Query: 1274 PLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSMEV--TVNAVAG 1331
P+ V+ C+ IE GL +EGLYRVSG ++++ FD+D +S+ + +N + G
Sbjct: 282 PMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITG 341
Query: 1332 ALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHL 1391
ALK +F DLP PLI Y +P+ +E+AKI D E+L L E +K P + + RY++ HL
Sbjct: 342 ALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHL 401
Query: 1392 NRVSQQHKINLMTADNLSICFWPTLMR-PDFENREFLSTTKIHQSVVETFIQQCQFFF 1448
RV+ K NLM A+NL I F PTLMR P+ + L+ + + VVE I+ F
Sbjct: 402 KRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF 459
>gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]
Length = 433
Score = 128 bits (322), Expect = 4e-29
Identities = 71/178 (39%), Positives = 104/178 (58%), Gaps = 3/178 (1%)
Query: 1274 PLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSMEV--TVNAVAG 1331
P+ V+ C+ IE GL +EGLYRVSG ++++ FD+D +S+ + +N + G
Sbjct: 256 PMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITG 315
Query: 1332 ALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHL 1391
ALK +F DLP PLI Y +P+ +E+AKI D E+L L E +K P + + RY++ HL
Sbjct: 316 ALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHL 375
Query: 1392 NRVSQQHKINLMTADNLSICFWPTLMR-PDFENREFLSTTKIHQSVVETFIQQCQFFF 1448
RV+ K NLM A+NL I F PTLMR P+ + L+ + + VVE I+ F
Sbjct: 376 KRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF 433
>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
sapiens]
Length = 521
Score = 122 bits (307), Expect = 2e-27
Identities = 69/227 (30%), Positives = 118/227 (51%), Gaps = 3/227 (1%)
Query: 1224 DKKMKKKTHKVKEDKKKKKTKNFNPPTRRNWESNYFGMPLQDLVTAEKP-IPLFVEKCVE 1282
+ + K HK+++ +++ T + + + FG L L E+ +P FV++C+
Sbjct: 293 ESDLSKVRHKLRKFLQRRPTLQ-SLREKGYIKDQVFGCALAALCERERSRVPRFVQQCIR 351
Query: 1283 FIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSME-VTVNAVAGALKAFFADLP 1341
+E GL +GLYR+SGN ++ + D D ++L V+ + GALK FF +LP
Sbjct: 352 AVEARGLDIDGLYRISGNLATIQKLRYKVDHDERLDLDDGRWEDVHVITGALKLFFRELP 411
Query: 1342 DPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHLNRVSQQHKIN 1401
+PL P+S + + A K+ D+ R ++++V+ N+D R + HL RV + + N
Sbjct: 412 EPLFPFSHFRQFIAAIKLQDQARRSRCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQN 471
Query: 1402 LMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETFIQQCQFFF 1448
M+ +++I F PTL+RP+ E T VVE +QQC F
Sbjct: 472 RMSVQSVAIVFGPTLLRPEVEETSMPMTMVFQNQVVELILQQCADIF 518
>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sapiens]
Length = 548
Score = 122 bits (307), Expect = 2e-27
Identities = 69/227 (30%), Positives = 118/227 (51%), Gaps = 3/227 (1%)
Query: 1224 DKKMKKKTHKVKEDKKKKKTKNFNPPTRRNWESNYFGMPLQDLVTAEKP-IPLFVEKCVE 1282
+ + K HK+++ +++ T + + + FG L L E+ +P FV++C+
Sbjct: 320 ESDLSKVRHKLRKFLQRRPTLQ-SLREKGYIKDQVFGCALAALCERERSRVPRFVQQCIR 378
Query: 1283 FIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSME-VTVNAVAGALKAFFADLP 1341
+E GL +GLYR+SGN ++ + D D ++L V+ + GALK FF +LP
Sbjct: 379 AVEARGLDIDGLYRISGNLATIQKLRYKVDHDERLDLDDGRWEDVHVITGALKLFFRELP 438
Query: 1342 DPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHLNRVSQQHKIN 1401
+PL P+S + + A K+ D+ R ++++V+ N+D R + HL RV + + N
Sbjct: 439 EPLFPFSHFRQFIAAIKLQDQARRSRCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQN 498
Query: 1402 LMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETFIQQCQFFF 1448
M+ +++I F PTL+RP+ E T VVE +QQC F
Sbjct: 499 RMSVQSVAIVFGPTLLRPEVEETSMPMTMVFQNQVVELILQQCADIF 545
>gi|4757980 beta chimerin isoform 2 [Homo sapiens]
Length = 468
Score = 122 bits (305), Expect = 3e-27
Identities = 67/172 (38%), Positives = 99/172 (57%), Gaps = 6/172 (3%)
Query: 1274 PLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSMEV--TVNAVAG 1331
P+ V+ C+ IE GL +EGLYRVSG ++++ FD+D +S V +N + G
Sbjct: 291 PMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITG 350
Query: 1332 ALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHL 1391
ALK +F DLP P+I Y + + ++AAKI + ERL A+ E++ P +Y+ RY++ HL
Sbjct: 351 ALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHL 410
Query: 1392 NRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETFIQQ 1443
+V+ K N M A+NL I F PTLMRP E + T +H + I Q
Sbjct: 411 KKVTMNEKDNFMNAENLGIVFGPTLMRPP----EDSTLTTLHDMRYQKLIVQ 458
>gi|91106928 beta chimerin isoform 1 [Homo sapiens]
Length = 332
Score = 122 bits (305), Expect = 3e-27
Identities = 67/172 (38%), Positives = 99/172 (57%), Gaps = 6/172 (3%)
Query: 1274 PLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSMEV--TVNAVAG 1331
P+ V+ C+ IE GL +EGLYRVSG ++++ FD+D +S V +N + G
Sbjct: 155 PMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITG 214
Query: 1332 ALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHL 1391
ALK +F DLP P+I Y + + ++AAKI + ERL A+ E++ P +Y+ RY++ HL
Sbjct: 215 ALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHL 274
Query: 1392 NRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETFIQQ 1443
+V+ K N M A+NL I F PTLMRP E + T +H + I Q
Sbjct: 275 KKVTMNEKDNFMNAENLGIVFGPTLMRPP----EDSTLTTLHDMRYQKLIVQ 322
>gi|188497642 ARHGAP15 [Homo sapiens]
Length = 475
Score = 115 bits (289), Expect = 2e-25
Identities = 64/196 (32%), Positives = 101/196 (51%), Gaps = 2/196 (1%)
Query: 1259 FGMPLQDLVTAEKP-IPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNI 1317
FG L + E +P FV++C+E +E GL +G+YRVSGN ++ +Q+ +
Sbjct: 279 FGSHLHKVCERENSTVPWFVKQCIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVNQEEKL 338
Query: 1318 NLVSME-VTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKF 1376
NL + ++ V GALK FF +LP+PL PYS + +EA K D R+ A+K +V+K
Sbjct: 339 NLDDSQWEDIHVVTGALKMFFRELPEPLFPYSFFEQFVEAIKKQDNNTRIEAVKSLVQKL 398
Query: 1377 HPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSV 1436
P N D + + HL ++ + NLM+ +L I F PTL+R + E +
Sbjct: 399 PPPNRDTMKVLFGHLTKIVAKASKNLMSTQSLGIVFGPTLLRAENETGNMAIHMVYQNQI 458
Query: 1437 VETFIQQCQFFFYNGE 1452
E + + F + E
Sbjct: 459 AELMLSEYSKIFGSEE 474
>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
Length = 846
Score = 108 bits (271), Expect = 3e-23
Identities = 73/255 (28%), Positives = 125/255 (49%), Gaps = 19/255 (7%)
Query: 1212 DNPAITS-DQELDDKKMKK----KTHKVKEDKKKKKTKNFN------PPTRRNWESNY-- 1258
D+P I D+E + K KK K + ++KK KN P + E Y
Sbjct: 591 DSPGIEKHDKEKEQKDPKKLRSFKVSSIDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIK 650
Query: 1259 ---FGMPLQDLVTAEK-PIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQD 1314
FG L +L E +P FV+ C+E +E+ GL +G+YRVSGN ++ + D
Sbjct: 651 DQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHD 710
Query: 1315 HNINLVSME-VTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIV 1373
++L + ++ + GALK FF +LP+PL ++ + + A K + +R+ A+K+++
Sbjct: 711 EKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIK-QEPRQRVAAVKDLI 769
Query: 1374 KKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIH 1433
++ N D + + HL RV + + N MT +++I F PTL++P+ E T
Sbjct: 770 RQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIAVHTVYQ 829
Query: 1434 QSVVETFIQQCQFFF 1448
+VE + + F
Sbjct: 830 NQIVELILLELSSIF 844
>gi|229094128 active breakpoint cluster region-related protein
isoform c [Homo sapiens]
Length = 813
Score = 106 bits (264), Expect = 2e-22
Identities = 61/212 (28%), Positives = 118/212 (55%), Gaps = 10/212 (4%)
Query: 1221 ELDDKKMKKKTHKVKEDKKKKKTKNFNPPTRRNWESNYFGMPLQDLVTAEKP-IPLFVEK 1279
E++ K++ D K+T P+++ ++ FG+ + + E+ +P V +
Sbjct: 568 EMNGIKVEFSMKFTSRDMSLKRT-----PSKK--QTGVFGVKISVVTKRERSKVPYIVRQ 620
Query: 1280 CVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDH-NINLVSMEVTVNAVAGALKAFFA 1338
CVE +E G+ G+YR+SG TD ++ FD ++ +I L+ ++ +NA+AG LK +F
Sbjct: 621 CVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFR 680
Query: 1339 DLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHLNRVSQQH 1398
+LP+PL+ L+P +E + D + + + +++ N F +++ HL RV+++
Sbjct: 681 ELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKE 740
Query: 1399 KINLMTADNLSICFWPTLMRP-DFENREFLST 1429
IN M+ NL+ F PTL+RP + E++ L++
Sbjct: 741 PINKMSLHNLATVFGPTLLRPSEVESKAHLTS 772
>gi|38679957 active breakpoint cluster region-related protein isoform
a [Homo sapiens]
Length = 859
Score = 106 bits (264), Expect = 2e-22
Identities = 61/212 (28%), Positives = 118/212 (55%), Gaps = 10/212 (4%)
Query: 1221 ELDDKKMKKKTHKVKEDKKKKKTKNFNPPTRRNWESNYFGMPLQDLVTAEKP-IPLFVEK 1279
E++ K++ D K+T P+++ ++ FG+ + + E+ +P V +
Sbjct: 614 EMNGIKVEFSMKFTSRDMSLKRT-----PSKK--QTGVFGVKISVVTKRERSKVPYIVRQ 666
Query: 1280 CVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDH-NINLVSMEVTVNAVAGALKAFFA 1338
CVE +E G+ G+YR+SG TD ++ FD ++ +I L+ ++ +NA+AG LK +F
Sbjct: 667 CVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFR 726
Query: 1339 DLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHLNRVSQQH 1398
+LP+PL+ L+P +E + D + + + +++ N F +++ HL RV+++
Sbjct: 727 ELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKE 786
Query: 1399 KINLMTADNLSICFWPTLMRP-DFENREFLST 1429
IN M+ NL+ F PTL+RP + E++ L++
Sbjct: 787 PINKMSLHNLATVFGPTLLRPSEVESKAHLTS 818
>gi|38679954 active breakpoint cluster region-related protein isoform
b [Homo sapiens]
Length = 822
Score = 106 bits (264), Expect = 2e-22
Identities = 61/212 (28%), Positives = 118/212 (55%), Gaps = 10/212 (4%)
Query: 1221 ELDDKKMKKKTHKVKEDKKKKKTKNFNPPTRRNWESNYFGMPLQDLVTAEKP-IPLFVEK 1279
E++ K++ D K+T P+++ ++ FG+ + + E+ +P V +
Sbjct: 577 EMNGIKVEFSMKFTSRDMSLKRT-----PSKK--QTGVFGVKISVVTKRERSKVPYIVRQ 629
Query: 1280 CVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDH-NINLVSMEVTVNAVAGALKAFFA 1338
CVE +E G+ G+YR+SG TD ++ FD ++ +I L+ ++ +NA+AG LK +F
Sbjct: 630 CVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFR 689
Query: 1339 DLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHLNRVSQQH 1398
+LP+PL+ L+P +E + D + + + +++ N F +++ HL RV+++
Sbjct: 690 ELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKE 749
Query: 1399 KINLMTADNLSICFWPTLMRP-DFENREFLST 1429
IN M+ NL+ F PTL+RP + E++ L++
Sbjct: 750 PINKMSLHNLATVFGPTLLRPSEVESKAHLTS 781
>gi|5803145 ralA binding protein 1 [Homo sapiens]
Length = 655
Score = 105 bits (261), Expect = 4e-22
Identities = 86/297 (28%), Positives = 136/297 (45%), Gaps = 35/297 (11%)
Query: 1143 KSHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFTTSKTKR-KGRHRGSEEDPLL 1201
K HG++ K K+K K K Y D+S DEA + SK KR KG H + P
Sbjct: 66 KDHGKK---KGKFKKK---EKRTEGYAAFQEDSSGDEAESPSKMKRSKGIHVFKK--PSF 117
Query: 1202 SPVETWKGGIDNPAITSDQELDDKKMKKKTHKVKEDK-------------KKKKTKNFNP 1248
S + I +++ ++K K++ HK K+ K KKKK K
Sbjct: 118 SKKKEKDFKIKEKP--KEEKHKEEKHKEEKHKEKKSKDLTAADVVKQWKEKKKKKKPIQE 175
Query: 1249 PTRRNWE----SNYFGMPLQDLVTAEKP-----IPLFVEKCVEFIEDTGLCTEGLYRVSG 1299
P + FG+PL D V +P +C++++E G+ EG+YRVSG
Sbjct: 176 PEVPQIDVPNLKPIFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSG 235
Query: 1300 NKTDQDNIQKQFDQDHNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKI 1359
K+ D ++ +D++ + NL E N VA LK + DLP+ L+ L P EA
Sbjct: 236 IKSKVDELKAAYDREESTNLEDYEP--NTVASLLKQYLRDLPENLLTKELMPRFEEACGR 293
Query: 1360 PDKTERLHALKEIVKKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTL 1416
+TE++ + ++K+ NY + ++I H++ V + M N+SI PT+
Sbjct: 294 TTETEKVQEFQRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTV 350
>gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]
Length = 1227
Score = 102 bits (255), Expect = 2e-21
Identities = 55/173 (31%), Positives = 97/173 (56%), Gaps = 4/173 (2%)
Query: 1249 PTRRNWESNYFGMPLQDLVTAEKP-IPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNI 1307
P+R+ ++ FG+ + + E+ +P V +CVE IE G+ G+YRVSG TD +
Sbjct: 1000 PSRK--QTGVFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQAL 1057
Query: 1308 QKQFDQDH-NINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERL 1366
+ FD ++ +++++ E+ VNA+AG LK +F +LP+PL +P E + D +
Sbjct: 1058 KAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKE 1117
Query: 1367 HALKEIVKKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRP 1419
+ ++ N F +++ HL RV+++ +N M+ NL+ F PTL+RP
Sbjct: 1118 SCMLNLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRP 1170
>gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]
Length = 1271
Score = 102 bits (255), Expect = 2e-21
Identities = 55/173 (31%), Positives = 97/173 (56%), Gaps = 4/173 (2%)
Query: 1249 PTRRNWESNYFGMPLQDLVTAEKP-IPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNI 1307
P+R+ ++ FG+ + + E+ +P V +CVE IE G+ G+YRVSG TD +
Sbjct: 1044 PSRK--QTGVFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQAL 1101
Query: 1308 QKQFDQDH-NINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERL 1366
+ FD ++ +++++ E+ VNA+AG LK +F +LP+PL +P E + D +
Sbjct: 1102 KAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKE 1161
Query: 1367 HALKEIVKKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRP 1419
+ ++ N F +++ HL RV+++ +N M+ NL+ F PTL+RP
Sbjct: 1162 SCMLNLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRP 1214
>gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]
Length = 1397
Score = 102 bits (254), Expect = 3e-21
Identities = 66/231 (28%), Positives = 119/231 (51%), Gaps = 7/231 (3%)
Query: 1259 FGMPLQDL--VTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDH- 1315
FG+ L++ T + +PL V C +E GL + G+YRV GN ++Q+Q ++
Sbjct: 809 FGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPG 868
Query: 1316 NINLVSME-VTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVK 1374
+INL +N ++ LK+FF LP+PL + + +EA +I D ER+ L+++++
Sbjct: 869 DINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIR 928
Query: 1375 KFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFEN-REFLSTTKIH 1433
Y+ ++++ HL ++ + N M NL++ F PTL+R +N + ++
Sbjct: 929 DLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDR 988
Query: 1434 QSVVETFIQQCQFFFYNGEIV-ETTNIVAPPPPSNPG-QLVEPMVPLQLPP 1482
+VET IQ +FF + E E T + P + P + + P + +PP
Sbjct: 989 YKIVETLIQHSDWFFSDEEDKGERTPVGDKEPQAVPNIEYLLPNIGRTVPP 1039
>gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
sapiens]
Length = 748
Score = 100 bits (250), Expect = 8e-21
Identities = 78/265 (29%), Positives = 121/265 (45%), Gaps = 16/265 (6%)
Query: 1192 HRGSEEDPLLSPVETWKGGIDNPAITSDQELDDKKMKKKTHKVKEDKKKKKTKNFNPPTR 1251
H +EE+P E GG D +T++ E + T ED K + P
Sbjct: 73 HPCNEENPGKFLFEVVPGG-DRDRMTANHE--SYLLMASTQNDMEDWVKSIRRVIWGP-- 127
Query: 1252 RNWESNYFGMPLQDLVTAEKPI-----PLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDN 1306
+ FG L+D V EK P+ VE+CV+FI GL EGL+R+ G
Sbjct: 128 --FGGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKE 185
Query: 1307 IQKQFDQDHNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTER- 1365
+Q FD + S V+ VA LK + +LP+P+IPY+ + + L AK+ K E
Sbjct: 186 LQDAFDCGEKPSFDS-NTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEA 244
Query: 1366 -LHALKEIVKKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFEN- 1423
+ L + VK VNY++ +Y+ L+ V +N M+ NL+ F P ++RP E+
Sbjct: 245 GVKELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDP 304
Query: 1424 REFLSTTKIHQSVVETFIQQCQFFF 1448
+ T + Q ++ I + F
Sbjct: 305 LTIMEGTVVVQQLMSVMISKHDCLF 329
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 100 bits (250), Expect = 8e-21
Identities = 62/198 (31%), Positives = 107/198 (54%), Gaps = 5/198 (2%)
Query: 1255 ESNYFGMPLQD-LVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQ 1313
E FG PL++ L + + I L +E CV + +TG+ EGL+R+ + ++ D
Sbjct: 246 EKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDC 305
Query: 1314 DHNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIV 1373
+ +L +AVAGALK++ +LP+PL+ ++L+ E + A + D+ ++L L
Sbjct: 306 STS-HLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTC 364
Query: 1374 KKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLM--RPDFENREFLSTTK 1431
+K P N+ FRY+I L +++Q +N MT N++I P L+ R + E + T
Sbjct: 365 QKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMAAATS 424
Query: 1432 IH-QSVVETFIQQCQFFF 1448
+H +V+E IQ +FF
Sbjct: 425 VHVVAVIEPIIQHADWFF 442
>gi|54860105 nadrin isoform 2 [Homo sapiens]
Length = 803
Score = 100 bits (250), Expect = 8e-21
Identities = 62/198 (31%), Positives = 107/198 (54%), Gaps = 5/198 (2%)
Query: 1255 ESNYFGMPLQD-LVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQ 1313
E FG PL++ L + + I L +E CV + +TG+ EGL+R+ + ++ D
Sbjct: 246 EKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDC 305
Query: 1314 DHNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIV 1373
+ +L +AVAGALK++ +LP+PL+ ++L+ E + A + D+ ++L L
Sbjct: 306 STS-HLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTC 364
Query: 1374 KKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLM--RPDFENREFLSTTK 1431
+K P N+ FRY+I L +++Q +N MT N++I P L+ R + E + T
Sbjct: 365 QKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMAAATS 424
Query: 1432 IH-QSVVETFIQQCQFFF 1448
+H +V+E IQ +FF
Sbjct: 425 VHVVAVIEPIIQHADWFF 442
>gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo
sapiens]
Length = 655
Score = 100 bits (249), Expect = 1e-20
Identities = 63/204 (30%), Positives = 100/204 (49%), Gaps = 9/204 (4%)
Query: 1253 NWESNYFGMPLQDLVTAEKPI-----PLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNI 1307
++ FG L+D V EK P+ VE+CV+FI GL EGL+R+ G +
Sbjct: 34 SFRKGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKEL 93
Query: 1308 QKQFDQDHNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTER-- 1365
Q FD + S V+ VA LK + +LP+P+IPY+ + + L AK+ K E
Sbjct: 94 QDAFDCGEKPSFDS-NTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAG 152
Query: 1366 LHALKEIVKKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFEN-R 1424
+ L + VK VNY++ +Y+ L+ V +N M+ NL+ F P ++RP E+
Sbjct: 153 VKELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPL 212
Query: 1425 EFLSTTKIHQSVVETFIQQCQFFF 1448
+ T + Q ++ I + F
Sbjct: 213 TIMEGTVVVQQLMSVMISKHDCLF 236
>gi|50843948 Rho GTPase activating protein 10 [Homo sapiens]
Length = 786
Score = 100 bits (249), Expect = 1e-20
Identities = 64/201 (31%), Positives = 93/201 (46%), Gaps = 7/201 (3%)
Query: 1277 VEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSMEVT----VNAVAGA 1332
+ KC+ +E G+ +GLYRV G + + N V +E + V + A
Sbjct: 399 IRKCISAVETRGINDQGLYRVVGVSSKVQRLLSMLMDVKTCNEVDLENSADWEVKTITSA 458
Query: 1333 LKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHLN 1392
LK + LP+PL+ Y LH + + AK R++A+ +V K N ++ ++ HL
Sbjct: 459 LKQYLRSLPEPLMTYELHGDFIVPAKSGSPESRVNAIHFLVHKLPEKNKEMLDILVKHLT 518
Query: 1393 RVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETFIQQCQFFFY--- 1449
VS K NLMT NL + F PTLMRP E L K VVE I+ + F
Sbjct: 519 NVSNHSKQNLMTVANLGVVFGPTLMRPQEETVAALMDLKFQNIVVEILIENHEKIFRTPP 578
Query: 1450 NGEIVETTNIVAPPPPSNPGQ 1470
+ E T + A PP + P Q
Sbjct: 579 DTTFPEPTCLSASPPNAPPRQ 599
>gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo
sapiens]
Length = 653
Score = 100 bits (248), Expect = 1e-20
Identities = 63/198 (31%), Positives = 98/198 (49%), Gaps = 9/198 (4%)
Query: 1259 FGMPLQDLVTAEKPI-----PLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQ 1313
FG L+D V EK P+ VE+CV+FI GL EGL+R+ G +Q FD
Sbjct: 38 FGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDC 97
Query: 1314 DHNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTER--LHALKE 1371
+ S V+ VA LK + +LP+P+IPY+ + + L AK+ K E + L +
Sbjct: 98 GEKPSFDS-NTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAK 156
Query: 1372 IVKKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFEN-REFLSTT 1430
VK VNY++ +Y+ L+ V +N M+ NL+ F P ++RP E+ + T
Sbjct: 157 QVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGT 216
Query: 1431 KIHQSVVETFIQQCQFFF 1448
+ Q ++ I + F
Sbjct: 217 VVVQQLMSVMISKHDCLF 234
>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
Length = 1958
Score = 100 bits (248), Expect = 1e-20
Identities = 69/245 (28%), Positives = 117/245 (47%), Gaps = 18/245 (7%)
Query: 1218 SDQELDDKKMKKKTHKVKEDKKKKKTKNFNPPTRRNWE-----SNYFGMPLQDLVTAE-- 1270
S +E ++K+ K K K R+ +E + FG+ L D A
Sbjct: 1099 SPKEESERKLLSKDDTSPPKDKGTWRKGIPSIMRKTFEKKPTATGTFGVRLDDCPPAHTN 1158
Query: 1271 KPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSMEVT----- 1325
+ IPL V+ C + +E+ GL G+YRV GN ++Q++ N + +++
Sbjct: 1159 RYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEEL----NKGMADIDIQDDKWR 1214
Query: 1326 -VNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVF 1384
+N ++ LK+FF LP+PL + + +EA + D +RL LK ++ +Y+
Sbjct: 1215 DLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLKRLIHDLPEHHYETL 1274
Query: 1385 RYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQ-SVVETFIQQ 1443
+++ HL V++ + N M NL+I F PTL+R +N + T Q +VET IQ
Sbjct: 1275 KFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQH 1334
Query: 1444 CQFFF 1448
+FF
Sbjct: 1335 HDWFF 1339
>gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b [Homo
sapiens]
Length = 1075
Score = 99.0 bits (245), Expect = 3e-20
Identities = 58/175 (33%), Positives = 94/175 (53%), Gaps = 10/175 (5%)
Query: 1273 IPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSM-EVTVNAVAG 1331
IPL VE C+ +I GL +G++RV G++ + ++I+ F++ + + E +N+VAG
Sbjct: 495 IPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAG 554
Query: 1332 ALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHL 1391
LK +F L +PL P +L+ K+ + ER+H +++I+ V V RY+ L
Sbjct: 555 VLKLYFRGLENPLFPKERFQDLISTIKLENPAERVHQIQQILVTLPRVVIVVMRYLFAFL 614
Query: 1392 NRVSQQHKINLMTADNLSICFWPTLMR-PDFEN--------REFLSTTKIHQSVV 1437
N +SQ N+M NL+ICF PTLM PD ++ E + T IH +
Sbjct: 615 NHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSCQAHINEVIKTIIIHHEAI 669
>gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a [Homo
sapiens]
Length = 1099
Score = 99.0 bits (245), Expect = 3e-20
Identities = 58/175 (33%), Positives = 94/175 (53%), Gaps = 10/175 (5%)
Query: 1273 IPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSM-EVTVNAVAG 1331
IPL VE C+ +I GL +G++RV G++ + ++I+ F++ + + E +N+VAG
Sbjct: 519 IPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAG 578
Query: 1332 ALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHL 1391
LK +F L +PL P +L+ K+ + ER+H +++I+ V V RY+ L
Sbjct: 579 VLKLYFRGLENPLFPKERFQDLISTIKLENPAERVHQIQQILVTLPRVVIVVMRYLFAFL 638
Query: 1392 NRVSQQHKINLMTADNLSICFWPTLMR-PDFEN--------REFLSTTKIHQSVV 1437
N +SQ N+M NL+ICF PTLM PD ++ E + T IH +
Sbjct: 639 NHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSCQAHINEVIKTIIIHHEAI 693
>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
Length = 818
Score = 99.0 bits (245), Expect = 3e-20
Identities = 59/203 (29%), Positives = 111/203 (54%), Gaps = 6/203 (2%)
Query: 1255 ESNYFGMPLQDLVTAE-KPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQ 1313
E FG PL++ +T + I +E CV + + G+ EGL+RV+ + + ++ D
Sbjct: 249 EKPSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDC 308
Query: 1314 DHNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIV 1373
+++ +A+AGALK++ +LP+PL+ + L+ E ++A+ + ++ ++L AL
Sbjct: 309 CV-VDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNAC 367
Query: 1374 KKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFENR--EFLSTTK 1431
+K N++ RY+I L+++S+ +N MT N++I P L+ P E E ++T
Sbjct: 368 EKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVS 427
Query: 1432 IH-QSVVETFIQQCQFFFYNGEI 1453
+ ++E IQ +FF GEI
Sbjct: 428 LQIVGIIEPIIQHADWFF-PGEI 449
>gi|156071465 Rho GTPase activating protein 4 [Homo sapiens]
Length = 946
Score = 98.2 bits (243), Expect = 5e-20
Identities = 76/321 (23%), Positives = 144/321 (44%), Gaps = 29/321 (9%)
Query: 1186 TKRKGRHRGSEEDPLLSPVETWKGGIDNPAITSDQELDDKKMKKKTHKVKEDKK------ 1239
+++ GR RG +++ + + + +I + + +K+++ + ++++
Sbjct: 423 SRQAGRRRGQQQETETFYLTKLQEYLSGRSILAKLQAKHEKLQEALQRGDKEEQEVSWTQ 482
Query: 1240 ---KKKTKNFNPPTRRNWESNYFGMPLQDLVTAE-KPIPLFVEKCVEFIEDTGLCTEGLY 1295
+K K+ P + FG ++ + + +P+PL VE C+ FI GL EG++
Sbjct: 483 YTQRKFQKSRQPRPSSQYNQRLFGGDMEKFIQSSGQPVPLVVESCIRFINLNGLQHEGIF 542
Query: 1296 RVSGNKTDQDNIQKQFDQDHNINLVSMEV-TVNAVAGALKAFFADLPDPLIPYSLHPELL 1354
RVSG + I+ F++ + + +++VAG LK +F L PL P L ELL
Sbjct: 543 RVSGAQLRVSEIRDAFERGEDPLVEGCTAHDLDSVAGVLKLYFRSLEPPLFPPDLFGELL 602
Query: 1355 EAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWP 1414
++++ ER+ + ++ + V RY+ T LN ++Q N+M NL++CF P
Sbjct: 603 ASSELEATAERVEHVSRLLWRLPAPVLVVLRYLFTFLNHLAQYSDENMMDPYNLAVCFGP 662
Query: 1415 TLMRPDFENREFLSTTKIHQSVVETFIQQCQFFFYNGEIVETTNIVAPPPPSNPGQLVEP 1474
TL+ +++Q V +Q + F PP S PG + E
Sbjct: 663 TLLPVPAGQDPVALQGRVNQLVQTLIVQPDRVF--------------PPLTSLPGPVYEK 708
Query: 1475 MVPLQLPPPLQPQLIQPQLQT 1495
+ PP L QL++
Sbjct: 709 C----MAPPSASCLGDAQLES 725
>gi|4505507 oligophrenin 1 [Homo sapiens]
Length = 802
Score = 97.1 bits (240), Expect = 1e-19
Identities = 60/192 (31%), Positives = 91/192 (47%), Gaps = 4/192 (2%)
Query: 1276 FVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDH---NINLVSMEVTVNAVAGA 1332
FV KC+ IE G+ TEGLYR G+ + F +++ + + + + +
Sbjct: 389 FVRKCINIIETKGIKTEGLYRTVGSNIQVQKLLNAFFDPKCPGDVDFHNSDWDIKTITSS 448
Query: 1333 LKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHLN 1392
LK + +L +P++ Y LH EL+ AAK + RL A+ +V K N ++ +I HL
Sbjct: 449 LKFYLRNLSEPVMTYRLHKELVSAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIRHLV 508
Query: 1393 RVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETFIQQCQFFFYNGE 1452
V + K NLMT N+ + F PTLMR + + K VVE I+ Y G
Sbjct: 509 NVCEHSKENLMTPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIVVEILIEHFG-KIYLGP 567
Query: 1453 IVETTNIVAPPP 1464
E+ PPP
Sbjct: 568 PEESAAPPVPPP 579
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,744,218
Number of Sequences: 37866
Number of extensions: 2843302
Number of successful extensions: 12577
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 114
Number of HSP's successfully gapped in prelim test: 164
Number of HSP's that attempted gapping in prelim test: 11781
Number of HSP's gapped (non-prelim): 744
length of query: 1501
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1386
effective length of database: 13,892,928
effective search space: 19255598208
effective search space used: 19255598208
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.