Guide to the Human Genome
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Search of human proteins with 71040094

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|71040094 ADP-ribosylation factor interacting protein 1
isoform 1 [Homo sapiens]
         (373 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|71040094 ADP-ribosylation factor interacting protein 1 isofor...   733   0.0  
gi|71040092 ADP-ribosylation factor interacting protein 1 isofor...   656   0.0  
gi|7657210 ADP-ribosylation factor interacting protein 1 isoform...   656   0.0  
gi|6912602 ADP-ribosylation factor interacting protein 2 [Homo s...   399   e-111
gi|88758603 protein interacting with C kinase 1 [Homo sapiens]         62   1e-09
gi|88758600 protein interacting with C kinase 1 [Homo sapiens]         62   1e-09
gi|7110697 protein interacting with C kinase 1 [Homo sapiens]          62   1e-09
gi|22095388 islet cell autoantigen 1,69kDa-like isoform 1 [Homo ...    55   1e-07
gi|209862841 islet cell autoantigen 1 [Homo sapiens]                   41   0.002
gi|94721350 islet cell autoantigen 1 [Homo sapiens]                    41   0.002
gi|12545395 islet cell autoantigen 1 [Homo sapiens]                    41   0.002
gi|71061468 centromere protein E [Homo sapiens]                        40   0.004
gi|34878904 synaptonemal complex protein 1 [Homo sapiens]              37   0.037
gi|64085252 hypothetical protein LOC145508 [Homo sapiens]              37   0.037
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa...    35   0.083
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s...    35   0.083
gi|238908495 similar to pleckstrin homology domain protein (5V32...    34   0.19 
gi|118498356 kinectin 1 isoform a [Homo sapiens]                       33   0.54 
gi|118498368 kinectin 1 isoform c [Homo sapiens]                       33   0.54 
gi|33620775 kinectin 1 isoform a [Homo sapiens]                        33   0.54 
gi|116517224 coiled-coil domain containing 144B [Homo sapiens]         33   0.54 
gi|149363642 coiled-coil domain containing 144A [Homo sapiens]         33   0.54 
gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens]        32   0.92 
gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo...    32   0.92 
gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens]          32   0.92 
gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens]          32   0.92 
gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens]         32   0.92 
gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens]          32   0.92 
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...    32   0.92 
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...    32   0.92 

>gi|71040094 ADP-ribosylation factor interacting protein 1 isoform 1
           [Homo sapiens]
          Length = 373

 Score =  733 bits (1892), Expect = 0.0
 Identities = 373/373 (100%), Positives = 373/373 (100%)

Query: 1   MAQESPKNSAAEIPVTSNGEVDDSREHSFNRDLKHSLPSGLGLSETQITSHGFDNTKEGV 60
           MAQESPKNSAAEIPVTSNGEVDDSREHSFNRDLKHSLPSGLGLSETQITSHGFDNTKEGV
Sbjct: 1   MAQESPKNSAAEIPVTSNGEVDDSREHSFNRDLKHSLPSGLGLSETQITSHGFDNTKEGV 60

Query: 61  IEAGAFQGSPAPPLPSVMSPSRVAASRLAQQGSDLIVPAGGQRTQTKSGPVILADEIKNP 120
           IEAGAFQGSPAPPLPSVMSPSRVAASRLAQQGSDLIVPAGGQRTQTKSGPVILADEIKNP
Sbjct: 61  IEAGAFQGSPAPPLPSVMSPSRVAASRLAQQGSDLIVPAGGQRTQTKSGPVILADEIKNP 120

Query: 121 AMEKLELVRKWSLNTYKCTRQIISEKLGRGSRTVDLELEAQIDILRDNKKKYENILKLAQ 180
           AMEKLELVRKWSLNTYKCTRQIISEKLGRGSRTVDLELEAQIDILRDNKKKYENILKLAQ
Sbjct: 121 AMEKLELVRKWSLNTYKCTRQIISEKLGRGSRTVDLELEAQIDILRDNKKKYENILKLAQ 180

Query: 181 TLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNADTQKLLAKNGETLLGAINFFIA 240
           TLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNADTQKLLAKNGETLLGAINFFIA
Sbjct: 181 TLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNADTQKLLAKNGETLLGAINFFIA 240

Query: 241 SVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEELNLGPRDANTLPKIEQSQHLFQAH 300
           SVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEELNLGPRDANTLPKIEQSQHLFQAH
Sbjct: 241 SVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEELNLGPRDANTLPKIEQSQHLFQAH 300

Query: 301 KEKYDKMRNDVSVKLKFLEENKVKVLHNQLVLFHNAIAAYFAGNQKQLEQTLKQFHIKLK 360
           KEKYDKMRNDVSVKLKFLEENKVKVLHNQLVLFHNAIAAYFAGNQKQLEQTLKQFHIKLK
Sbjct: 301 KEKYDKMRNDVSVKLKFLEENKVKVLHNQLVLFHNAIAAYFAGNQKQLEQTLKQFHIKLK 360

Query: 361 TPGVDAPSWLEEQ 373
           TPGVDAPSWLEEQ
Sbjct: 361 TPGVDAPSWLEEQ 373


>gi|71040092 ADP-ribosylation factor interacting protein 1 isoform 2
           [Homo sapiens]
          Length = 341

 Score =  656 bits (1692), Expect = 0.0
 Identities = 341/373 (91%), Positives = 341/373 (91%), Gaps = 32/373 (8%)

Query: 1   MAQESPKNSAAEIPVTSNGEVDDSREHSFNRDLKHSLPSGLGLSETQITSHGFDNTKEGV 60
           MAQESPKNSAAEIPVTSNGEVDDSREHSFNRDLKHSLPSGLGLSETQITSHGFDNTKEGV
Sbjct: 1   MAQESPKNSAAEIPVTSNGEVDDSREHSFNRDLKHSLPSGLGLSETQITSHGFDNTKEGV 60

Query: 61  IEAGAFQGSPAPPLPSVMSPSRVAASRLAQQGSDLIVPAGGQRTQTKSGPVILADEIKNP 120
           IEAGAFQG                                GQRTQTKSGPVILADEIKNP
Sbjct: 61  IEAGAFQG--------------------------------GQRTQTKSGPVILADEIKNP 88

Query: 121 AMEKLELVRKWSLNTYKCTRQIISEKLGRGSRTVDLELEAQIDILRDNKKKYENILKLAQ 180
           AMEKLELVRKWSLNTYKCTRQIISEKLGRGSRTVDLELEAQIDILRDNKKKYENILKLAQ
Sbjct: 89  AMEKLELVRKWSLNTYKCTRQIISEKLGRGSRTVDLELEAQIDILRDNKKKYENILKLAQ 148

Query: 181 TLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNADTQKLLAKNGETLLGAINFFIA 240
           TLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNADTQKLLAKNGETLLGAINFFIA
Sbjct: 149 TLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNADTQKLLAKNGETLLGAINFFIA 208

Query: 241 SVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEELNLGPRDANTLPKIEQSQHLFQAH 300
           SVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEELNLGPRDANTLPKIEQSQHLFQAH
Sbjct: 209 SVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEELNLGPRDANTLPKIEQSQHLFQAH 268

Query: 301 KEKYDKMRNDVSVKLKFLEENKVKVLHNQLVLFHNAIAAYFAGNQKQLEQTLKQFHIKLK 360
           KEKYDKMRNDVSVKLKFLEENKVKVLHNQLVLFHNAIAAYFAGNQKQLEQTLKQFHIKLK
Sbjct: 269 KEKYDKMRNDVSVKLKFLEENKVKVLHNQLVLFHNAIAAYFAGNQKQLEQTLKQFHIKLK 328

Query: 361 TPGVDAPSWLEEQ 373
           TPGVDAPSWLEEQ
Sbjct: 329 TPGVDAPSWLEEQ 341


>gi|7657210 ADP-ribosylation factor interacting protein 1 isoform 2
           [Homo sapiens]
          Length = 341

 Score =  656 bits (1692), Expect = 0.0
 Identities = 341/373 (91%), Positives = 341/373 (91%), Gaps = 32/373 (8%)

Query: 1   MAQESPKNSAAEIPVTSNGEVDDSREHSFNRDLKHSLPSGLGLSETQITSHGFDNTKEGV 60
           MAQESPKNSAAEIPVTSNGEVDDSREHSFNRDLKHSLPSGLGLSETQITSHGFDNTKEGV
Sbjct: 1   MAQESPKNSAAEIPVTSNGEVDDSREHSFNRDLKHSLPSGLGLSETQITSHGFDNTKEGV 60

Query: 61  IEAGAFQGSPAPPLPSVMSPSRVAASRLAQQGSDLIVPAGGQRTQTKSGPVILADEIKNP 120
           IEAGAFQG                                GQRTQTKSGPVILADEIKNP
Sbjct: 61  IEAGAFQG--------------------------------GQRTQTKSGPVILADEIKNP 88

Query: 121 AMEKLELVRKWSLNTYKCTRQIISEKLGRGSRTVDLELEAQIDILRDNKKKYENILKLAQ 180
           AMEKLELVRKWSLNTYKCTRQIISEKLGRGSRTVDLELEAQIDILRDNKKKYENILKLAQ
Sbjct: 89  AMEKLELVRKWSLNTYKCTRQIISEKLGRGSRTVDLELEAQIDILRDNKKKYENILKLAQ 148

Query: 181 TLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNADTQKLLAKNGETLLGAINFFIA 240
           TLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNADTQKLLAKNGETLLGAINFFIA
Sbjct: 149 TLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNADTQKLLAKNGETLLGAINFFIA 208

Query: 241 SVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEELNLGPRDANTLPKIEQSQHLFQAH 300
           SVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEELNLGPRDANTLPKIEQSQHLFQAH
Sbjct: 209 SVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEELNLGPRDANTLPKIEQSQHLFQAH 268

Query: 301 KEKYDKMRNDVSVKLKFLEENKVKVLHNQLVLFHNAIAAYFAGNQKQLEQTLKQFHIKLK 360
           KEKYDKMRNDVSVKLKFLEENKVKVLHNQLVLFHNAIAAYFAGNQKQLEQTLKQFHIKLK
Sbjct: 269 KEKYDKMRNDVSVKLKFLEENKVKVLHNQLVLFHNAIAAYFAGNQKQLEQTLKQFHIKLK 328

Query: 361 TPGVDAPSWLEEQ 373
           TPGVDAPSWLEEQ
Sbjct: 329 TPGVDAPSWLEEQ 341


>gi|6912602 ADP-ribosylation factor interacting protein 2 [Homo
           sapiens]
          Length = 341

 Score =  399 bits (1026), Expect = e-111
 Identities = 206/369 (55%), Positives = 266/369 (72%), Gaps = 37/369 (10%)

Query: 7   KNSAAEIPVTSNGEVDDSREHS-FNRDLKHSLPSGLGLSETQITSHGFDNTKEGVIEAGA 65
           K +  EIP+  NGE     E     +DL+  + SG  L+ET I S G+  + +G+I  G 
Sbjct: 8   KAATMEIPIHGNGEARQLPEDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGDGLIPTG- 66

Query: 66  FQGSPAPPLPSVMSPSRVAASRLAQQGSDLIVPAGGQRTQTKSGPVILADEI-KNPAMEK 124
                     S   PS                      + T SGP    DE+ +  A EK
Sbjct: 67  ----------SGRHPSH---------------------STTPSGP---GDEVARGIAGEK 92

Query: 125 LELVRKWSLNTYKCTRQIISEKLGRGSRTVDLELEAQIDILRDNKKKYENILKLAQTLST 184
            ++V+KW +NTYKCT+Q++SE+ GRGSRTVDLELE QI++LR+ K+KYE++L+L + L+ 
Sbjct: 93  FDIVKKWGINTYKCTKQLLSERFGRGSRTVDLELELQIELLRETKRKYESVLQLGRALTA 152

Query: 185 QLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNADTQKLLAKNGETLLGAINFFIASVNT 244
            L+ ++ TQ  LGDAFADLS KS EL EEFGYNA+TQKLL KNGETLLGA+NFF++S+NT
Sbjct: 153 HLYSLLQTQHALGDAFADLSQKSPELQEEFGYNAETQKLLCKNGETLLGAVNFFVSSINT 212

Query: 245 LVNKTIEDTLMTVKQYESARIEYDAYRTDLEELNLGPRDANTLPKIEQSQHLFQAHKEKY 304
           LV KT+EDTLMTVKQYE+AR+EYDAYRTDLEEL+LGPRDA T  ++E +Q  FQAH++KY
Sbjct: 213 LVTKTMEDTLMTVKQYEAARLEYDAYRTDLEELSLGPRDAGTRGRLESAQATFQAHRDKY 272

Query: 305 DKMRNDVSVKLKFLEENKVKVLHNQLVLFHNAIAAYFAGNQKQLEQTLKQFHIKLKTPGV 364
           +K+R DV++KLKFLEENK+KV+H QL+LFHNA++AYFAGNQKQLEQTL+QF+IKL+ PG 
Sbjct: 273 EKLRGDVAIKLKFLEENKIKVMHKQLLLFHNAVSAYFAGNQKQLEQTLQQFNIKLRPPGA 332

Query: 365 DAPSWLEEQ 373
           + PSWLEEQ
Sbjct: 333 EKPSWLEEQ 341


>gi|88758603 protein interacting with C kinase 1 [Homo sapiens]
          Length = 415

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 44/197 (22%), Positives = 92/197 (46%), Gaps = 13/197 (6%)

Query: 158 LEAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLE--LHEEFG 215
           L  +++ L    + Y+ + +  + L    +++  T R  GD F+ + ++  +    E F 
Sbjct: 149 LVKRLEELERTAELYKGMTEHTKNLLRAFYELSQTHRAFGDVFSVIGVREPQPAASEAFV 208

Query: 216 YNADTQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLE 275
             AD  + + K G  LL  I   +  +NT +NK I DT +T+K+Y   + EY +Y   ++
Sbjct: 209 KFADAHRSIEKFGIRLLKTIKPMLTDLNTYLNKAIPDTRLTIKKYLDVKFEYLSYCLKVK 268

Query: 276 ELNLGPRD----ANTLPKIEQSQHLF-------QAHKEKYDKMRNDVSVKLKFLEENKVK 324
           E++            L ++    + +       Q  + ++ +MR DV  K++ L++  V+
Sbjct: 269 EMDDEEYSCIALGEPLYRVSTGNYEYRLILRCRQEARARFSQMRKDVLEKMELLDQKHVQ 328

Query: 325 VLHNQLVLFHNAIAAYF 341
            +  QL    + ++ Y+
Sbjct: 329 DIVFQLQRLVSTMSKYY 345


>gi|88758600 protein interacting with C kinase 1 [Homo sapiens]
          Length = 415

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 44/197 (22%), Positives = 92/197 (46%), Gaps = 13/197 (6%)

Query: 158 LEAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLE--LHEEFG 215
           L  +++ L    + Y+ + +  + L    +++  T R  GD F+ + ++  +    E F 
Sbjct: 149 LVKRLEELERTAELYKGMTEHTKNLLRAFYELSQTHRAFGDVFSVIGVREPQPAASEAFV 208

Query: 216 YNADTQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLE 275
             AD  + + K G  LL  I   +  +NT +NK I DT +T+K+Y   + EY +Y   ++
Sbjct: 209 KFADAHRSIEKFGIRLLKTIKPMLTDLNTYLNKAIPDTRLTIKKYLDVKFEYLSYCLKVK 268

Query: 276 ELNLGPRD----ANTLPKIEQSQHLF-------QAHKEKYDKMRNDVSVKLKFLEENKVK 324
           E++            L ++    + +       Q  + ++ +MR DV  K++ L++  V+
Sbjct: 269 EMDDEEYSCIALGEPLYRVSTGNYEYRLILRCRQEARARFSQMRKDVLEKMELLDQKHVQ 328

Query: 325 VLHNQLVLFHNAIAAYF 341
            +  QL    + ++ Y+
Sbjct: 329 DIVFQLQRLVSTMSKYY 345


>gi|7110697 protein interacting with C kinase 1 [Homo sapiens]
          Length = 415

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 44/197 (22%), Positives = 92/197 (46%), Gaps = 13/197 (6%)

Query: 158 LEAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLE--LHEEFG 215
           L  +++ L    + Y+ + +  + L    +++  T R  GD F+ + ++  +    E F 
Sbjct: 149 LVKRLEELERTAELYKGMTEHTKNLLRAFYELSQTHRAFGDVFSVIGVREPQPAASEAFV 208

Query: 216 YNADTQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLE 275
             AD  + + K G  LL  I   +  +NT +NK I DT +T+K+Y   + EY +Y   ++
Sbjct: 209 KFADAHRSIEKFGIRLLKTIKPMLTDLNTYLNKAIPDTRLTIKKYLDVKFEYLSYCLKVK 268

Query: 276 ELNLGPRD----ANTLPKIEQSQHLF-------QAHKEKYDKMRNDVSVKLKFLEENKVK 324
           E++            L ++    + +       Q  + ++ +MR DV  K++ L++  V+
Sbjct: 269 EMDDEEYSCIALGEPLYRVSTGNYEYRLILRCRQEARARFSQMRKDVLEKMELLDQKHVQ 328

Query: 325 VLHNQLVLFHNAIAAYF 341
            +  QL    + ++ Y+
Sbjct: 329 DIVFQLQRLVSTMSKYY 345


>gi|22095388 islet cell autoantigen 1,69kDa-like isoform 1 [Homo
           sapiens]
          Length = 482

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 52/246 (21%), Positives = 103/246 (41%), Gaps = 13/246 (5%)

Query: 115 DEIKNPAMEKLELVRKWSLNTYKCTRQIISEKLGRGSR----TVDLELEAQIDILRDNKK 170
           D    P  E  + V +     Y  T+Q+  +  G+         D EL+A++++    ++
Sbjct: 2   DSFGQPRPEDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQE 61

Query: 171 KYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNAD-TQKLL---AK 226
               +LK+ +    +L  +   + +LG     L  ++     + G   D T K L   AK
Sbjct: 62  TCTELLKIIEKYQLRLNVISEEENELG---LFLKFQAERDATQAGKMMDATGKALCSSAK 118

Query: 227 NGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEELN--LGPRDA 284
               L   ++     V T   + + DTLMT+ + E AR EY      +++++  L P   
Sbjct: 119 QRLALCTPLSRLKQEVATFSQRAVSDTLMTINRMEQARTEYRGALLWMKDVSQELDPDTL 178

Query: 285 NTLPKIEQSQHLFQAHKEKYDKMRNDVSVKLKFLEENKVKVLHNQLVLFHNAIAAYFAGN 344
             + K  + Q   +  K  +DK++ DV  K+  L  ++  +L + L  +   +  ++   
Sbjct: 179 KQMEKFRKVQMQVRNSKASFDKLKMDVCQKVDLLGASRCNMLSHSLTTYQRTLLGFWKKT 238

Query: 345 QKQLEQ 350
            + + Q
Sbjct: 239 ARMMSQ 244


>gi|209862841 islet cell autoantigen 1 [Homo sapiens]
          Length = 483

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 28/125 (22%), Positives = 56/125 (44%), Gaps = 6/125 (4%)

Query: 238 FIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEELN--LGPRDANTLPKIEQSQH 295
           F   V T  ++ I DT +TV + E  R EY      +++++  L P     + K  + Q 
Sbjct: 137 FHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELDPDLYKQMEKFRKVQT 196

Query: 296 LFQAHKEKYDKMRNDVSVKLKFLEENKVKVLHNQLVLFHNAIAAYFAGNQKQLEQTLKQF 355
             +  K+ +DK++ DV  K+  L  ++  +L + L  +   +  ++    ++   T+   
Sbjct: 197 QVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFW----EKTSHTMAAI 252

Query: 356 HIKLK 360
           H   K
Sbjct: 253 HESFK 257


>gi|94721350 islet cell autoantigen 1 [Homo sapiens]
          Length = 483

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 28/125 (22%), Positives = 56/125 (44%), Gaps = 6/125 (4%)

Query: 238 FIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEELN--LGPRDANTLPKIEQSQH 295
           F   V T  ++ I DT +TV + E  R EY      +++++  L P     + K  + Q 
Sbjct: 137 FHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELDPDLYKQMEKFRKVQT 196

Query: 296 LFQAHKEKYDKMRNDVSVKLKFLEENKVKVLHNQLVLFHNAIAAYFAGNQKQLEQTLKQF 355
             +  K+ +DK++ DV  K+  L  ++  +L + L  +   +  ++    ++   T+   
Sbjct: 197 QVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFW----EKTSHTMAAI 252

Query: 356 HIKLK 360
           H   K
Sbjct: 253 HESFK 257


>gi|12545395 islet cell autoantigen 1 [Homo sapiens]
          Length = 483

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 28/125 (22%), Positives = 56/125 (44%), Gaps = 6/125 (4%)

Query: 238 FIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEELN--LGPRDANTLPKIEQSQH 295
           F   V T  ++ I DT +TV + E  R EY      +++++  L P     + K  + Q 
Sbjct: 137 FHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELDPDLYKQMEKFRKVQT 196

Query: 296 LFQAHKEKYDKMRNDVSVKLKFLEENKVKVLHNQLVLFHNAIAAYFAGNQKQLEQTLKQF 355
             +  K+ +DK++ DV  K+  L  ++  +L + L  +   +  ++    ++   T+   
Sbjct: 197 QVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFW----EKTSHTMAAI 252

Query: 356 HIKLK 360
           H   K
Sbjct: 253 HESFK 257


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 50/225 (22%), Positives = 94/225 (41%), Gaps = 41/225 (18%)

Query: 102  QRTQTKSGPVILADEIKNPAMEKLELVR---KWSLNTYKCTRQIISEKLGRGSRTV-DLE 157
            Q+    S   + A ++K    E+L +     K    T    R I+SEK  + S    DLE
Sbjct: 1755 QKDLEHSNDALKAQDLK--IQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLE 1812

Query: 158  -----LEAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGD---AFADLSLKSLE 209
                 L+ +I  L+ N+ +   + K       ++ +M   ++Q+ D     + L +++L 
Sbjct: 1813 NSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLN 1872

Query: 210  LHEEFGYNADTQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYESARIEYDA 269
            L ++   N +  K + K  + L                + +E+TL         ++E D 
Sbjct: 1873 LAQKLHENLEEMKSVMKERDNL----------------RRVEETL---------KLERDQ 1907

Query: 270  YRTDLEELNLGPRDANTLPKIEQSQHLFQAHKEKYDKMRNDVSVK 314
             +  L+E     RD     +++ ++ L + HKE  DK+R  +S K
Sbjct: 1908 LKESLQETKA--RDLEIQQELKTARMLSKEHKETVDKLREKISEK 1950



 Score = 29.6 bits (65), Expect = 4.6
 Identities = 24/101 (23%), Positives = 48/101 (47%), Gaps = 20/101 (19%)

Query: 245 LVNKTIEDTLMTVK-QYESARIEYDAYRTDLEELNLGPRDANTLPKIE---------QSQ 294
           L  + IE  L +++  Y++  ++Y+  RT+ EE+ L  ++ N L + E         Q  
Sbjct: 491 LNQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEM 550

Query: 295 HLFQ---------AHKEKYDK-MRNDVSVKLKFLEENKVKV 325
            L            H E Y++ + N++S K++ L E + ++
Sbjct: 551 QLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQI 591


>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
          Length = 976

 Score = 36.6 bits (83), Expect = 0.037
 Identities = 70/299 (23%), Positives = 121/299 (40%), Gaps = 47/299 (15%)

Query: 113 LADEIKNPAMEKLELVRKWSLNTYKCTRQIISEK-LGRGSRTVDLELEAQIDILRDNKKK 171
           L  E++N  ++  EL       T  C +  +  K L + +  + LEL+ Q + + +NKK+
Sbjct: 502 LKTELENEKLKNTEL-------TSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQ 554

Query: 172 YENILKLAQTL---STQL-FQMVHTQRQLGDAFADLSLKSLELHEEFGYNADTQ------ 221
            E +LK  + L    TQL  ++ + + +L     ++  K L+  EE   N   Q      
Sbjct: 555 EERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCK-LDKSEENCNNLRKQVENKNK 613

Query: 222 ---------KLLAKNGETLLGAINFFIASVNTL-------VNKTIEDTLMTVKQYESARI 265
                    K L K G      +N +   VN L         K  E T    K+ E  +I
Sbjct: 614 YIEELQQENKALKKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKI 673

Query: 266 EYDAYRTDLEELNLGPRDANTLP---------KIEQSQHLFQAHKEKYDKM--RNDVSVK 314
             +    ++E+  +   +A  L          KI +   L + HK +YDK+    D  + 
Sbjct: 674 SEENLLEEVEKAKVIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELG 733

Query: 315 LKFLEENKVKVLHNQLVLFHNAIAAYFAGNQKQLEQTLKQFHIKLKTPGVDAPSWLEEQ 373
           L   +E +   L   L +  + + A     +KQLE   ++   KLK    +  + L+E+
Sbjct: 734 LYKSKEQEQSSLRASLEIELSNLKAELLSVKKQLEIEREEKE-KLKREAKENTATLKEK 791


>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
          Length = 1094

 Score = 36.6 bits (83), Expect = 0.037
 Identities = 55/234 (23%), Positives = 103/234 (44%), Gaps = 30/234 (12%)

Query: 115 DEIKNP---AMEKLELVRKWSLNTYKCTRQIISEKLGRG--------SRTVDLELEAQID 163
           DE+K     A++++E +RK  LN     R +  E+L           S   DLELE +  
Sbjct: 526 DELKTQLYAALQQIENLRK-ELNDVLTKRALQEEELHSKEEKLRDIKSHQADLELEVKNS 584

Query: 164 ILRDNKKKYENILKLAQTLSTQL-FQMVHTQRQLGD---AFADLSLKSLELHEEF----G 215
           +  D   + E+ LK    + +Q+  +  H + ++ +   + A    K LE+ E       
Sbjct: 585 L--DTIHRLESELKKQSKIQSQMKVEKAHLEEEIAELKKSQAQDKAKLLEMQESIKDLSA 642

Query: 216 YNADTQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLE 275
             AD    LA+  E    A+   ++ +        E+T   + Q    ++E D ++ +L+
Sbjct: 643 IRADLANKLAEE-ERAKKAVLKDLSDLTAQAKSRDEETATIITQL---KLERDVHQRELK 698

Query: 276 ELNLGPRDANTLPKIEQS-QHLFQAHKEKYDKMRNDV-SVKLKFLEENKVKVLH 327
           +L    +   T  K EQ+ Q L +  K++  +  N + ++K + LEE  +  +H
Sbjct: 699 DLTSSLQSVKT--KHEQNIQELMKHFKKEKSEAENHIRTLKAESLEEKNMAKIH 750



 Score = 30.4 bits (67), Expect = 2.7
 Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 15/95 (15%)

Query: 123 EKLELVRKWSLNTYKCTRQIISEKLGRGSRTVDLELEAQIDILRDNKKKYENILKLAQTL 182
           E L+L  + S+  +K   + +   L + S TVD EL            K   ILK    L
Sbjct: 480 EDLKLKAQESIRQWKLKHKKLERALEKQSETVD-ELTG----------KNNQILKEKDEL 528

Query: 183 STQLF----QMVHTQRQLGDAFADLSLKSLELHEE 213
            TQL+    Q+ + +++L D     +L+  ELH +
Sbjct: 529 KTQLYAALQQIENLRKELNDVLTKRALQEEELHSK 563


>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
           sapiens]
          Length = 1843

 Score = 35.4 bits (80), Expect = 0.083
 Identities = 47/200 (23%), Positives = 83/200 (41%), Gaps = 33/200 (16%)

Query: 158 LEAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADL----------SLKS 207
           LE +   L    +K +  L   + L+ QL  +     QL +   +L          S+K 
Sbjct: 661 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM 720

Query: 208 LELHEEFGYNADTQKLLAKNGETLLGA---------INFFIASV-NTLVNKTIEDTLMTV 257
            +L  E     +++K   K G  LL A         +++    + N  + KT+E++   +
Sbjct: 721 AQLQLE-NKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKI 779

Query: 258 KQYESA----RIEYDAYRTDLEELNLGPRDANTLPK----IEQSQHLFQAHKEKYDK--- 306
           +Q ES      +E    + +LEEL +  +    L K    +EQ     +  K++ +K   
Sbjct: 780 QQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENK 839

Query: 307 -MRNDVSVKLKFLEENKVKV 325
            +R    +K   LEEN VK+
Sbjct: 840 RLRQQAEIKDTTLEENNVKI 859


>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
           sapiens]
          Length = 1870

 Score = 35.4 bits (80), Expect = 0.083
 Identities = 47/200 (23%), Positives = 83/200 (41%), Gaps = 33/200 (16%)

Query: 158 LEAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADL----------SLKS 207
           LE +   L    +K +  L   + L+ QL  +     QL +   +L          S+K 
Sbjct: 661 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM 720

Query: 208 LELHEEFGYNADTQKLLAKNGETLLGA---------INFFIASV-NTLVNKTIEDTLMTV 257
            +L  E     +++K   K G  LL A         +++    + N  + KT+E++   +
Sbjct: 721 AQLQLE-NKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKI 779

Query: 258 KQYESA----RIEYDAYRTDLEELNLGPRDANTLPK----IEQSQHLFQAHKEKYDK--- 306
           +Q ES      +E    + +LEEL +  +    L K    +EQ     +  K++ +K   
Sbjct: 780 QQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENK 839

Query: 307 -MRNDVSVKLKFLEENKVKV 325
            +R    +K   LEEN VK+
Sbjct: 840 RLRQQAEIKDTTLEENNVKI 859


>gi|238908495 similar to pleckstrin homology domain protein (5V327)
           [Homo sapiens]
          Length = 506

 Score = 34.3 bits (77), Expect = 0.19
 Identities = 56/233 (24%), Positives = 96/233 (41%), Gaps = 31/233 (13%)

Query: 122 MEKLELVRKWSLNTYKCTRQIISEKLGRGSRTVDLELEAQIDILRDNKKKYENILKL--- 178
           ME+ ++ R+  L T +C + +  EK  +  R +   L+  ++ L   KKK   +L+    
Sbjct: 210 MEQEQIKRELEL-TARCLKGVEQEK--KELRHLTESLQQTLEELSIEKKKTLEMLEENEN 266

Query: 179 -AQTLSTQLFQM-----VHTQ-RQLGDAFADLSLKSLELHEEFGYNADTQKLLAKNGETL 231
             QTL+ Q  Q      +H+  RQ+ +    L  + L   +    N +  + L +  E  
Sbjct: 267 HLQTLANQSEQPPPSGGLHSNLRQIEEKMQQLLEEKLLAEKRMKENEERSRALEEERE-- 324

Query: 232 LGAINFFIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEELNLGPRDANTLPKIE 291
                 F +S +  +  ++++     +Q E         R DLE        A  L  +E
Sbjct: 325 ------FYSSQSQALQNSLQELTAEKQQAERELKAEVKVRMDLERRLREAEGA--LRSLE 376

Query: 292 QSQHLFQAHKEKYDKMRNDVSVKLKFLE--------ENKVKVLHNQLVLFHNA 336
           Q  +    +KEK ++MR DVS   +F E        E K+ V+    V  H A
Sbjct: 377 QGLNSKVRNKEKEERMRADVSHLKRFFEECIRNAELEAKMPVIMKNSVYIHKA 429


>gi|118498356 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 32.7 bits (73), Expect = 0.54
 Identities = 43/206 (20%), Positives = 85/206 (41%), Gaps = 14/206 (6%)

Query: 169 KKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNADTQKL--LAK 226
           ++K E +  + + L T L Q+   + +L     + S  + E+ +      D      L +
Sbjct: 738 QEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVE 797

Query: 227 NGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEELNLGP-RDAN 285
             + ++   +  I SV  L+   +       K  +  + E  A + ++  + L   +  +
Sbjct: 798 ELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLS 857

Query: 286 TLPKIEQSQHLFQAHKEKYDKMRNDVSVKLKFL-----------EENKVKVLHNQLVLFH 334
              K+++ Q+L +  +E+ + M+  +  K K L           EEN+    H Q V  H
Sbjct: 858 ITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQH 917

Query: 335 NAIAAYFAGNQKQLEQTLKQFHIKLK 360
           N   A  A   ++LE  LK+   +LK
Sbjct: 918 NLKEASSASQFEELEIVLKEKENELK 943


>gi|118498368 kinectin 1 isoform c [Homo sapiens]
          Length = 1300

 Score = 32.7 bits (73), Expect = 0.54
 Identities = 43/206 (20%), Positives = 85/206 (41%), Gaps = 14/206 (6%)

Query: 169 KKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNADTQKL--LAK 226
           ++K E +  + + L T L Q+   + +L     + S  + E+ +      D      L +
Sbjct: 738 QEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVE 797

Query: 227 NGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEELNLGP-RDAN 285
             + ++   +  I SV  L+   +       K  +  + E  A + ++  + L   +  +
Sbjct: 798 ELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLS 857

Query: 286 TLPKIEQSQHLFQAHKEKYDKMRNDVSVKLKFL-----------EENKVKVLHNQLVLFH 334
              K+++ Q+L +  +E+ + M+  +  K K L           EEN+    H Q V  H
Sbjct: 858 ITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQH 917

Query: 335 NAIAAYFAGNQKQLEQTLKQFHIKLK 360
           N   A  A   ++LE  LK+   +LK
Sbjct: 918 NLKEASSASQFEELEIVLKEKENELK 943


>gi|33620775 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 32.7 bits (73), Expect = 0.54
 Identities = 43/206 (20%), Positives = 85/206 (41%), Gaps = 14/206 (6%)

Query: 169 KKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNADTQKL--LAK 226
           ++K E +  + + L T L Q+   + +L     + S  + E+ +      D      L +
Sbjct: 738 QEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVE 797

Query: 227 NGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEELNLGP-RDAN 285
             + ++   +  I SV  L+   +       K  +  + E  A + ++  + L   +  +
Sbjct: 798 ELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLS 857

Query: 286 TLPKIEQSQHLFQAHKEKYDKMRNDVSVKLKFL-----------EENKVKVLHNQLVLFH 334
              K+++ Q+L +  +E+ + M+  +  K K L           EEN+    H Q V  H
Sbjct: 858 ITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQH 917

Query: 335 NAIAAYFAGNQKQLEQTLKQFHIKLK 360
           N   A  A   ++LE  LK+   +LK
Sbjct: 918 NLKEASSASQFEELEIVLKEKENELK 943


>gi|116517224 coiled-coil domain containing 144B [Homo sapiens]
          Length = 725

 Score = 32.7 bits (73), Expect = 0.54
 Identities = 23/86 (26%), Positives = 47/86 (54%), Gaps = 9/86 (10%)

Query: 249 TIEDTLMTVKQYESARIEYDAYRTDLEELNLGPRDANTLPKIEQS----QHLFQAHKEKY 304
           ++E + +  +  E +   Y+ +   +E+L +  +D+ +LP+I+ +    +HL +      
Sbjct: 597 SMEPSEIASEDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHC 656

Query: 305 DKMRNDVSVKLKFLEENKVKVLHNQL 330
           D++    +VKLK + EN V VL N+L
Sbjct: 657 DQL----TVKLKQM-ENMVSVLQNEL 677


>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
          Length = 1427

 Score = 32.7 bits (73), Expect = 0.54
 Identities = 23/86 (26%), Positives = 47/86 (54%), Gaps = 9/86 (10%)

Query: 249 TIEDTLMTVKQYESARIEYDAYRTDLEELNLGPRDANTLPKIEQS----QHLFQAHKEKY 304
           ++E + +  +  E +   Y+ +   +E+L +  +D+ +LP+I+ +    +HL +      
Sbjct: 597 SMEPSEIASEDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHC 656

Query: 305 DKMRNDVSVKLKFLEENKVKVLHNQL 330
           D++    +VKLK + EN V VL N+L
Sbjct: 657 DQL----TVKLKQM-ENMVSVLQNEL 677


>gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens]
          Length = 917

 Score = 32.0 bits (71), Expect = 0.92
 Identities = 40/169 (23%), Positives = 69/169 (40%), Gaps = 15/169 (8%)

Query: 159 EAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNA 218
           E + D+ ++N    + I +L   + T   Q   T+ +          K +E+ +E   N 
Sbjct: 552 ERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKY--------FKDIEIIKE--NNE 601

Query: 219 DTQKLLAKNGETLLGAINFFIASVNTLV--NKTIEDTLMTVKQYES-ARIEYDAYRTDLE 275
           D +K L +N ETL   I  +   +N L+  N  +   L   KQ  S    E ++YR  L 
Sbjct: 602 DLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRLA 661

Query: 276 ELNLGPRDANTLPKIEQSQHLFQAHKEKYDKMRNDVSVKLKFLEENKVK 324
              L   D     K    Q  FQ+   ++  ++ D +  ++ L +   K
Sbjct: 662 AA-LCDHDQRQSSK-RDLQLAFQSTVNEWCHLQEDTNSHIQILSQQLSK 708


>gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo
           sapiens]
          Length = 917

 Score = 32.0 bits (71), Expect = 0.92
 Identities = 40/169 (23%), Positives = 69/169 (40%), Gaps = 15/169 (8%)

Query: 159 EAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNA 218
           E + D+ ++N    + I +L   + T   Q   T+ +          K +E+ +E   N 
Sbjct: 552 ERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKY--------FKDIEIIKE--NNE 601

Query: 219 DTQKLLAKNGETLLGAINFFIASVNTLV--NKTIEDTLMTVKQYES-ARIEYDAYRTDLE 275
           D +K L +N ETL   I  +   +N L+  N  +   L   KQ  S    E ++YR  L 
Sbjct: 602 DLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRLA 661

Query: 276 ELNLGPRDANTLPKIEQSQHLFQAHKEKYDKMRNDVSVKLKFLEENKVK 324
              L   D     K    Q  FQ+   ++  ++ D +  ++ L +   K
Sbjct: 662 AA-LCDHDQRQSSK-RDLQLAFQSTVNEWCHLQEDTNSHIQILSQQLSK 708


>gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens]
          Length = 445

 Score = 32.0 bits (71), Expect = 0.92
 Identities = 35/144 (24%), Positives = 61/144 (42%), Gaps = 12/144 (8%)

Query: 162 IDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNAD-- 219
           +D+  +N    + I  L QT    + ++   QRQL  A  +  L  +++      NA+  
Sbjct: 179 VDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVM 238

Query: 220 ---TQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEE 276
              T+KL ++  E L        A    L    +E+T   +K  E A  +  A    LEE
Sbjct: 239 REMTKKLYSQYEEKLQEEQRKHSAEKEAL----LEETNSFLKAIEEANKKMQAAEISLEE 294

Query: 277 LN--LGPRDANTLPKIEQSQHLFQ 298
            +  +G  D   + ++E+ +H  Q
Sbjct: 295 KDQRIGELD-RLIERMEKERHQLQ 317


>gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens]
          Length = 550

 Score = 32.0 bits (71), Expect = 0.92
 Identities = 35/144 (24%), Positives = 61/144 (42%), Gaps = 12/144 (8%)

Query: 162 IDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNAD-- 219
           +D+  +N    + I  L QT    + ++   QRQL  A  +  L  +++      NA+  
Sbjct: 179 VDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVM 238

Query: 220 ---TQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEE 276
              T+KL ++  E L        A    L    +E+T   +K  E A  +  A    LEE
Sbjct: 239 REMTKKLYSQYEEKLQEEQRKHSAEKEAL----LEETNSFLKAIEEANKKMQAAEISLEE 294

Query: 277 LN--LGPRDANTLPKIEQSQHLFQ 298
            +  +G  D   + ++E+ +H  Q
Sbjct: 295 KDQRIGELD-RLIERMEKERHQLQ 317


>gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens]
          Length = 438

 Score = 32.0 bits (71), Expect = 0.92
 Identities = 35/144 (24%), Positives = 61/144 (42%), Gaps = 12/144 (8%)

Query: 162 IDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNAD-- 219
           +D+  +N    + I  L QT    + ++   QRQL  A  +  L  +++      NA+  
Sbjct: 179 VDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVM 238

Query: 220 ---TQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEE 276
              T+KL ++  E L        A    L    +E+T   +K  E A  +  A    LEE
Sbjct: 239 REMTKKLYSQYEEKLQEEQRKHSAEKEAL----LEETNSFLKAIEEANKKMQAAEISLEE 294

Query: 277 LN--LGPRDANTLPKIEQSQHLFQ 298
            +  +G  D   + ++E+ +H  Q
Sbjct: 295 KDQRIGELD-RLIERMEKERHQLQ 317


>gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens]
          Length = 466

 Score = 32.0 bits (71), Expect = 0.92
 Identities = 35/144 (24%), Positives = 61/144 (42%), Gaps = 12/144 (8%)

Query: 162 IDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNAD-- 219
           +D+  +N    + I  L QT    + ++   QRQL  A  +  L  +++      NA+  
Sbjct: 179 VDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVM 238

Query: 220 ---TQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEE 276
              T+KL ++  E L        A    L    +E+T   +K  E A  +  A    LEE
Sbjct: 239 REMTKKLYSQYEEKLQEEQRKHSAEKEAL----LEETNSFLKAIEEANKKMQAAEISLEE 294

Query: 277 LN--LGPRDANTLPKIEQSQHLFQ 298
            +  +G  D   + ++E+ +H  Q
Sbjct: 295 KDQRIGELD-RLIERMEKERHQLQ 317


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 32.0 bits (71), Expect = 0.92
 Identities = 21/89 (23%), Positives = 45/89 (50%), Gaps = 3/89 (3%)

Query: 143  ISEKLGRGSRTVDLELEAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGDAFAD 202
            ++  L +  R  D  L        +++ + E  LK +++LST+LF++ +   +  D    
Sbjct: 1439 LAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLET 1498

Query: 203  LSLKSLELHEEFGYNADTQKLLAKNGETL 231
            +  ++  L +E    AD  + +A+NG+T+
Sbjct: 1499 VKRENKNLEQEI---ADLTEQIAENGKTI 1524


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score = 32.0 bits (71), Expect = 0.92
 Identities = 55/260 (21%), Positives = 101/260 (38%), Gaps = 49/260 (18%)

Query: 116  EIKNPAMEKLELVRKWSLNTYKCTRQIISEKLGRGSRTVDLELEAQIDILRDNKKKYENI 175
            E+    +EK E + +   N+ +    + S         +D E+ ++ D LR  KK   ++
Sbjct: 1575 ELDRKVIEKDEEIEQLKRNSQRAAEALQS--------VLDAEIRSRNDALRLKKKMEGDL 1626

Query: 176  LKLAQTLSTQLFQMVHTQRQLGDAFADLSLKSLELHEEFGYNADTQKLLAKNGETLLGAI 235
             ++   L     QM  TQ+ L      L    L L +    N D ++ LA          
Sbjct: 1627 NEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLA---------- 1676

Query: 236  NFFIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEELNLGPRDANTLPKIEQSQH 295
               +   N L+ + +E+  + ++Q E  R      R   +EL     DA+   ++  SQ+
Sbjct: 1677 --IVERRNGLLLEELEEMKVALEQTERTR------RLSEQEL----LDASDRVQLLHSQN 1724

Query: 296  LFQAHKEKYDKMRNDVSVKLKFLEENKVKVLHNQLVLFHNAI----------------AA 339
                + +K  K+  D++ + +   EN ++   N       AI                +A
Sbjct: 1725 TSLINTKK--KLEADIA-QCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSA 1781

Query: 340  YFAGNQKQLEQTLKQFHIKL 359
            +    +K LEQT+K    +L
Sbjct: 1782 HLERMKKNLEQTVKDLQHRL 1801



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 40/211 (18%), Positives = 91/211 (43%), Gaps = 15/211 (7%)

Query: 147  LGRGSRTVDLELEAQIDILRDNKKKYENILKLAQTLSTQLFQMVHTQRQLGDAFADLSLK 206
            L +  R  D  L      L +++ + E   K +++LST+LF+M +   ++ D    L  +
Sbjct: 1446 LDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRE 1505

Query: 207  SLELHEEFGYNADTQKLLAKNGETLLGAINFFIASVNTLVNKTIEDTLMTVKQYESARIE 266
            +  L EE    +D  + +A+ G+ L  A          LV +   D  + +++ E + +E
Sbjct: 1506 NKNLQEEI---SDLTEQIAETGKNLQEA-----EKTKKLVEQEKSDLQVALEEVEGS-LE 1556

Query: 267  YDAYRTDLEELNL----GPRDANTLPKIEQSQHLFQAHKEKYDKMRNDVSVKLKFLEENK 322
            ++  +    +L L       D   + K E+ + L +  +   + +++ +  +++    N 
Sbjct: 1557 HEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIR--SRND 1614

Query: 323  VKVLHNQLVLFHNAIAAYFAGNQKQLEQTLK 353
               L  ++    N +      + +Q+ +T K
Sbjct: 1615 ALRLKKKMEGDLNEMEIQLGHSNRQMAETQK 1645


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.130    0.357 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,347,942
Number of Sequences: 37866
Number of extensions: 592612
Number of successful extensions: 1884
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 64
Number of HSP's that attempted gapping in prelim test: 1843
Number of HSP's gapped (non-prelim): 109
length of query: 373
length of database: 18,247,518
effective HSP length: 104
effective length of query: 269
effective length of database: 14,309,454
effective search space: 3849243126
effective search space used: 3849243126
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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