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Search of human proteins with 70906435
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|70906435 fibrinogen, beta chain preproprotein [Homo sapiens]
(491 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|70906435 fibrinogen, beta chain preproprotein [Homo sapiens] 1036 0.0
gi|70906439 fibrinogen, gamma chain isoform gamma-B precursor [H... 234 1e-61
gi|70906437 fibrinogen, gamma chain isoform gamma-A precursor [H... 234 1e-61
gi|4503689 fibrinogen, alpha polypeptide isoform alpha-E preprop... 207 2e-53
gi|42544202 fibrinogen-like 1 precursor [Homo sapiens] 192 4e-49
gi|42544200 fibrinogen-like 1 precursor [Homo sapiens] 192 4e-49
gi|42544198 fibrinogen-like 1 precursor [Homo sapiens] 192 4e-49
gi|42544189 fibrinogen-like 1 precursor [Homo sapiens] 192 4e-49
gi|6912236 angiopoietin-like 2 precursor [Homo sapiens] 190 2e-48
gi|4757752 angiopoietin-like 1 precursor [Homo sapiens] 182 8e-46
gi|10863949 angiopoietin-like 7 [Homo sapiens] 179 5e-45
gi|29893555 angiopoietin-like 6 [Homo sapiens] 171 1e-42
gi|169646749 angiopoietin 2 isoform b precursor [Homo sapiens] 169 7e-42
gi|7705276 angiopoietin 4 [Homo sapiens] 168 1e-41
gi|5730075 fibrinogen-like 2 precursor [Homo sapiens] 168 1e-41
gi|169646754 angiopoietin 2 isoform c precursor [Homo sapiens] 167 2e-41
gi|4557315 angiopoietin 2 isoform a precursor [Homo sapiens] 167 2e-41
gi|223029463 fibrinogen C domain containing 1 [Homo sapiens] 165 1e-40
gi|223029461 fibrinogen C domain containing 1 [Homo sapiens] 165 1e-40
gi|20532340 angiopoietin 1 [Homo sapiens] 164 1e-40
gi|8051584 ficolin 1 precursor [Homo sapiens] 160 2e-39
gi|62988324 tenascin N [Homo sapiens] 157 2e-38
gi|8051586 ficolin 2 isoform b precursor [Homo sapiens] 155 6e-38
gi|61744445 ficolin 2 isoform a precursor [Homo sapiens] 155 6e-38
gi|27754778 ficolin 3 isoform 2 precursor [Homo sapiens] 155 8e-38
gi|27754776 ficolin 3 isoform 1 precursor [Homo sapiens] 155 8e-38
gi|157384973 tenascin R [Homo sapiens] 152 5e-37
gi|23111005 microfibrillar-associated protein 4 [Homo sapiens] 145 6e-35
gi|20665034 tenascin XB isoform 2 [Homo sapiens] 142 9e-34
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 142 9e-34
>gi|70906435 fibrinogen, beta chain preproprotein [Homo sapiens]
Length = 491
Score = 1036 bits (2679), Expect = 0.0
Identities = 491/491 (100%), Positives = 491/491 (100%)
Query: 1 MKRMVSWSFHKLKTMKHLLLLLLCVFLVKSQGVNDNEEGFFSARGHRPLDKKREEAPSLR 60
MKRMVSWSFHKLKTMKHLLLLLLCVFLVKSQGVNDNEEGFFSARGHRPLDKKREEAPSLR
Sbjct: 1 MKRMVSWSFHKLKTMKHLLLLLLCVFLVKSQGVNDNEEGFFSARGHRPLDKKREEAPSLR 60
Query: 61 PAPPPISGGGYRARPAKAAATQKKVERKAPDAGGCLHADPDLGVLCPTGCQLQEALLQQE 120
PAPPPISGGGYRARPAKAAATQKKVERKAPDAGGCLHADPDLGVLCPTGCQLQEALLQQE
Sbjct: 61 PAPPPISGGGYRARPAKAAATQKKVERKAPDAGGCLHADPDLGVLCPTGCQLQEALLQQE 120
Query: 121 RPIRNSVDELNNNVEAVSQTSSSSFQYMYLLKDLWQKRQKQVKDNENVVNEYSSELEKHQ 180
RPIRNSVDELNNNVEAVSQTSSSSFQYMYLLKDLWQKRQKQVKDNENVVNEYSSELEKHQ
Sbjct: 121 RPIRNSVDELNNNVEAVSQTSSSSFQYMYLLKDLWQKRQKQVKDNENVVNEYSSELEKHQ 180
Query: 181 LYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKE 240
LYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKE
Sbjct: 181 LYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKE 240
Query: 241 CEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYK 300
CEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYK
Sbjct: 241 CEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYK 300
Query: 301 QGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFT 360
QGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFT
Sbjct: 301 QGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFT 360
Query: 361 VQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDP 420
VQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDP
Sbjct: 361 VQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDP 420
Query: 421 RKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKM 480
RKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKM
Sbjct: 421 RKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKM 480
Query: 481 SMKIRPFFPQQ 491
SMKIRPFFPQQ
Sbjct: 481 SMKIRPFFPQQ 491
>gi|70906439 fibrinogen, gamma chain isoform gamma-B precursor [Homo
sapiens]
Length = 453
Score = 234 bits (597), Expect = 1e-61
Identities = 128/399 (32%), Positives = 208/399 (52%), Gaps = 23/399 (5%)
Query: 95 CLHADPDLGVLCPTGCQLQEALLQQERPIRNSVDELNNNVEAVSQTSSSSFQYMYLLKDL 154
C D G CPT C + + L + + + L + + V +S Q + ++
Sbjct: 34 CCILDERFGSYCPTTCGIADFLSTYQTKVDKDLQSLEDILHQVENKTSEVKQLIKAIQLT 93
Query: 155 WQKRQKQVKDNENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLES 214
+ + + + S ++ + + + ++ ++ +++R L+ I + KI L+
Sbjct: 94 YNPDESSKPNMIDAATLKSRKMLEEIMKYEASILTH-DSSIRYLQEIYNSNNQKIVNLKE 152
Query: 215 DVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNT 274
V+ C+ PC + I ++GK+C++I KG + S +Y I+P + + + VYC+++
Sbjct: 153 KVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDG 212
Query: 275 ENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVA-TNTDGKNYCGLPGEYWLGNDKISQLT 333
GWTV Q R DGSVDF + W YK+GFG+++ T T E+WLGN+KI ++
Sbjct: 213 SGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTT---------EFWLGNEKIHLIS 263
Query: 334 RMG--PTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLM 391
P L +E+EDW G A Y F V EA+KY+++ + G DG
Sbjct: 264 TQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFD--F 321
Query: 392 GE---NRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYW 448
G+ ++ T HNGM FST+D DND + C+++DG GWW N+CHA + NG YY
Sbjct: 322 GDDPSDKFFTSHNGMQFSTWDNDNDKF-----EGNCAEQDGSGWWMNKCHAGHLNGVYYQ 376
Query: 449 GGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPF 487
GG Y+ +G D+G++W WK WYSM+K +MKI PF
Sbjct: 377 GGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPF 415
>gi|70906437 fibrinogen, gamma chain isoform gamma-A precursor [Homo
sapiens]
Length = 437
Score = 234 bits (597), Expect = 1e-61
Identities = 128/399 (32%), Positives = 208/399 (52%), Gaps = 23/399 (5%)
Query: 95 CLHADPDLGVLCPTGCQLQEALLQQERPIRNSVDELNNNVEAVSQTSSSSFQYMYLLKDL 154
C D G CPT C + + L + + + L + + V +S Q + ++
Sbjct: 34 CCILDERFGSYCPTTCGIADFLSTYQTKVDKDLQSLEDILHQVENKTSEVKQLIKAIQLT 93
Query: 155 WQKRQKQVKDNENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLES 214
+ + + + S ++ + + + ++ ++ +++R L+ I + KI L+
Sbjct: 94 YNPDESSKPNMIDAATLKSRKMLEEIMKYEASILTH-DSSIRYLQEIYNSNNQKIVNLKE 152
Query: 215 DVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNT 274
V+ C+ PC + I ++GK+C++I KG + S +Y I+P + + + VYC+++
Sbjct: 153 KVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDG 212
Query: 275 ENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVA-TNTDGKNYCGLPGEYWLGNDKISQLT 333
GWTV Q R DGSVDF + W YK+GFG+++ T T E+WLGN+KI ++
Sbjct: 213 SGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTT---------EFWLGNEKIHLIS 263
Query: 334 RMG--PTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLM 391
P L +E+EDW G A Y F V EA+KY+++ + G DG
Sbjct: 264 TQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFD--F 321
Query: 392 GE---NRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYW 448
G+ ++ T HNGM FST+D DND + C+++DG GWW N+CHA + NG YY
Sbjct: 322 GDDPSDKFFTSHNGMQFSTWDNDNDKF-----EGNCAEQDGSGWWMNKCHAGHLNGVYYQ 376
Query: 449 GGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPF 487
GG Y+ +G D+G++W WK WYSM+K +MKI PF
Sbjct: 377 GGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPF 415
>gi|4503689 fibrinogen, alpha polypeptide isoform alpha-E
preproprotein [Homo sapiens]
Length = 866
Score = 207 bits (526), Expect = 2e-53
Identities = 113/287 (39%), Positives = 171/287 (59%), Gaps = 21/287 (7%)
Query: 207 SKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRK--GGETSEMYLIQPDSSVK 264
SK K+ + ++ ++ T T + ++C+++++ G S ++ I+ S K
Sbjct: 598 SKSYKMADEAGSEADHEGTHSTKRGHAKSRPVRDCDDVLQTHPSGTQSGIFNIKLPGSSK 657
Query: 265 PYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWL 324
+ VYCD T GGW +IQ R DGS++F R W YK+GFG++ N +G+ GE+WL
Sbjct: 658 IFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSL--NDEGE------GEFWL 709
Query: 325 GNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALM 384
GND + LT+ G + L +E+EDW G++ A Y F V +EA Y + V+ Y GTAG+AL+
Sbjct: 710 GNDYLHLLTQRG-SVLRVELEDWAGNEAYAEY-HFRVGSEAEGYALQVSSYEGTAGDALI 767
Query: 385 DGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNG 444
+G+ + E T HN M FST+DRD D W + C++ GGGWWYN C AAN NG
Sbjct: 768 EGSVE---EGAEYTSHNNMQFSTFDRDADQW-----EENCAEVYGGGWWYNNCQAANLNG 819
Query: 445 RYYWGGQY-TWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFFPQ 490
YY GG Y + + + ++GVVW++++G+ YS+R + MKIRP Q
Sbjct: 820 IYYPGGSYDPRNNSPYEIENGVVWVSFRGADYSLRAVRMKIRPLVTQ 866
Score = 43.1 bits (100), Expect = 6e-04
Identities = 23/134 (17%), Positives = 63/134 (47%), Gaps = 7/134 (5%)
Query: 98 ADPDLGVLCPTGCQLQEALLQQERPIRNSVDELNNNVEAVSQTSSSSFQYMYLLKDLWQK 157
+D D CP+GC+++ + + + N +++L N++ + + S + ++ +
Sbjct: 56 SDEDWNYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRG 115
Query: 158 RQKQVKDNENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKI---QKLES 214
+ +N N S +L E + + ++ ++ + +N+R+++ ++LE
Sbjct: 116 DFSSANNRDNTYNRVSEDLRSR----IEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEV 171
Query: 215 DVSAQMEYCRTPCT 228
D+ ++ CR C+
Sbjct: 172 DIDIKIRSCRGSCS 185
>gi|42544202 fibrinogen-like 1 precursor [Homo sapiens]
Length = 312
Score = 192 bits (489), Expect = 4e-49
Identities = 105/247 (42%), Positives = 140/247 (56%), Gaps = 24/247 (9%)
Query: 240 ECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPY 299
+C EI G + S Y I+P S + VYCDM+ + GGWTVIQ R DGS +F R W Y
Sbjct: 82 DCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDMS-DGGGWTVIQRRSDGSENFNRGWKDY 140
Query: 300 KQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGF 359
+ GFGN GEYWLGN + LT L I++ D++ + A Y F
Sbjct: 141 ENGFGNFVQKH---------GEYWLGNKNLHFLTTQEDYTLKIDLADFEKNSRYAQYKNF 191
Query: 360 TVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSD 419
V +E N Y++++ +Y GTAG++L A E + H M FST+DRD+D +
Sbjct: 192 KVGDEKNFYELNIGEYSGTAGDSL---AGNFHPEVQWWASHQRMKFSTWDRDHDNY---- 244
Query: 420 PRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRK 479
C++ED GWW+NRCH+AN NG YY G YT AK TD+G+VW W G WYS++
Sbjct: 245 -EGNCAEEDQSGWWFNRCHSANLNGVYY-SGPYT---AK--TDNGIVWYTWHGWWYSLKS 297
Query: 480 MSMKIRP 486
+ MKIRP
Sbjct: 298 VVMKIRP 304
>gi|42544200 fibrinogen-like 1 precursor [Homo sapiens]
Length = 312
Score = 192 bits (489), Expect = 4e-49
Identities = 105/247 (42%), Positives = 140/247 (56%), Gaps = 24/247 (9%)
Query: 240 ECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPY 299
+C EI G + S Y I+P S + VYCDM+ + GGWTVIQ R DGS +F R W Y
Sbjct: 82 DCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDMS-DGGGWTVIQRRSDGSENFNRGWKDY 140
Query: 300 KQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGF 359
+ GFGN GEYWLGN + LT L I++ D++ + A Y F
Sbjct: 141 ENGFGNFVQKH---------GEYWLGNKNLHFLTTQEDYTLKIDLADFEKNSRYAQYKNF 191
Query: 360 TVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSD 419
V +E N Y++++ +Y GTAG++L A E + H M FST+DRD+D +
Sbjct: 192 KVGDEKNFYELNIGEYSGTAGDSL---AGNFHPEVQWWASHQRMKFSTWDRDHDNY---- 244
Query: 420 PRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRK 479
C++ED GWW+NRCH+AN NG YY G YT AK TD+G+VW W G WYS++
Sbjct: 245 -EGNCAEEDQSGWWFNRCHSANLNGVYY-SGPYT---AK--TDNGIVWYTWHGWWYSLKS 297
Query: 480 MSMKIRP 486
+ MKIRP
Sbjct: 298 VVMKIRP 304
>gi|42544198 fibrinogen-like 1 precursor [Homo sapiens]
Length = 312
Score = 192 bits (489), Expect = 4e-49
Identities = 105/247 (42%), Positives = 140/247 (56%), Gaps = 24/247 (9%)
Query: 240 ECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPY 299
+C EI G + S Y I+P S + VYCDM+ + GGWTVIQ R DGS +F R W Y
Sbjct: 82 DCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDMS-DGGGWTVIQRRSDGSENFNRGWKDY 140
Query: 300 KQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGF 359
+ GFGN GEYWLGN + LT L I++ D++ + A Y F
Sbjct: 141 ENGFGNFVQKH---------GEYWLGNKNLHFLTTQEDYTLKIDLADFEKNSRYAQYKNF 191
Query: 360 TVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSD 419
V +E N Y++++ +Y GTAG++L A E + H M FST+DRD+D +
Sbjct: 192 KVGDEKNFYELNIGEYSGTAGDSL---AGNFHPEVQWWASHQRMKFSTWDRDHDNY---- 244
Query: 420 PRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRK 479
C++ED GWW+NRCH+AN NG YY G YT AK TD+G+VW W G WYS++
Sbjct: 245 -EGNCAEEDQSGWWFNRCHSANLNGVYY-SGPYT---AK--TDNGIVWYTWHGWWYSLKS 297
Query: 480 MSMKIRP 486
+ MKIRP
Sbjct: 298 VVMKIRP 304
>gi|42544189 fibrinogen-like 1 precursor [Homo sapiens]
Length = 312
Score = 192 bits (489), Expect = 4e-49
Identities = 105/247 (42%), Positives = 140/247 (56%), Gaps = 24/247 (9%)
Query: 240 ECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPY 299
+C EI G + S Y I+P S + VYCDM+ + GGWTVIQ R DGS +F R W Y
Sbjct: 82 DCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDMS-DGGGWTVIQRRSDGSENFNRGWKDY 140
Query: 300 KQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGF 359
+ GFGN GEYWLGN + LT L I++ D++ + A Y F
Sbjct: 141 ENGFGNFVQKH---------GEYWLGNKNLHFLTTQEDYTLKIDLADFEKNSRYAQYKNF 191
Query: 360 TVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSD 419
V +E N Y++++ +Y GTAG++L A E + H M FST+DRD+D +
Sbjct: 192 KVGDEKNFYELNIGEYSGTAGDSL---AGNFHPEVQWWASHQRMKFSTWDRDHDNY---- 244
Query: 420 PRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRK 479
C++ED GWW+NRCH+AN NG YY G YT AK TD+G+VW W G WYS++
Sbjct: 245 -EGNCAEEDQSGWWFNRCHSANLNGVYY-SGPYT---AK--TDNGIVWYTWHGWWYSLKS 297
Query: 480 MSMKIRP 486
+ MKIRP
Sbjct: 298 VVMKIRP 304
>gi|6912236 angiopoietin-like 2 precursor [Homo sapiens]
Length = 493
Score = 190 bits (483), Expect = 2e-48
Identities = 97/248 (39%), Positives = 140/248 (56%), Gaps = 36/248 (14%)
Query: 239 KECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDP 298
++C + + G +TS +YL++P+++ + +V+CD + GGWTVIQ R DGSV+F R W+
Sbjct: 276 RDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRNWET 335
Query: 299 YKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGG 358
YKQGFGN+ GEYWLG + I LT G +LL+ MEDW G KV A Y
Sbjct: 336 YKQGFGNI------------DGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYAS 383
Query: 359 FTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTS 418
F ++ E+ Y++ + +Y G AG+ + T HNG F+T DRD+D + +
Sbjct: 384 FRLEPESEYYKLRLGRYHGNAGD--------------SFTWHNGKQFTTLDRDHDVYTGN 429
Query: 419 DPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMR 478
C+ GGWWYN C +N NG +Y GG Y + DGV W ++G YS++
Sbjct: 430 -----CAHYQKGGWWYNACAHSNLNGVWYRGGHY-----RSRYQDGVYWAEFRGGSYSLK 479
Query: 479 KMSMKIRP 486
K+ M IRP
Sbjct: 480 KVVMMIRP 487
>gi|4757752 angiopoietin-like 1 precursor [Homo sapiens]
Length = 491
Score = 182 bits (461), Expect = 8e-46
Identities = 94/248 (37%), Positives = 139/248 (56%), Gaps = 36/248 (14%)
Query: 239 KECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDP 298
K+C++ G S +Y+I+P++S P +++C+ + + GGWTVIQ R DGSV+F R W+
Sbjct: 278 KDCQQAKEAGHSVSGIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWEN 337
Query: 299 YKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGG 358
YK+GFGN+ GEYWLG + I L+ +LLIE+EDW KV A Y
Sbjct: 338 YKKGFGNI------------DGEYWLGLENIYMLSNQDNYKLLIELEDWSDKKVYAEYSS 385
Query: 359 FTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTS 418
F ++ E+ Y++ + Y+G AG+++M HNG F+T DRD D + +
Sbjct: 386 FRLEPESEFYRLRLGTYQGNAGDSMM--------------WHNGKQFTTLDRDKDMYAGN 431
Query: 419 DPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMR 478
C+ GGWWYN C +N NG +Y GG Y +KH DG+ W ++G YS+R
Sbjct: 432 -----CAHFHKGGWWYNACAHSNLNGVWYRGGHY---RSKH--QDGIFWAEYRGGSYSLR 481
Query: 479 KMSMKIRP 486
+ M I+P
Sbjct: 482 AVQMMIKP 489
>gi|10863949 angiopoietin-like 7 [Homo sapiens]
Length = 346
Score = 179 bits (454), Expect = 5e-45
Identities = 108/329 (32%), Positives = 168/329 (51%), Gaps = 45/329 (13%)
Query: 161 QVKDNENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSA-Q 219
QV + ++++E + + E+ + + V + +N + + S L + SK ++ + + Q
Sbjct: 55 QVANLSSLLSELNKKQERDWVSVVMQV-MELESNSKRMESRLTDAESKYSEMNNQIDIMQ 113
Query: 220 MEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSV--KPYRVYCDMNTENG 277
++ +T S + +C + +K S +Y + PD + V+CDM T G
Sbjct: 114 LQAAQTVTQTSADAIY----DCSSLYQKNYRISGVYKLPPDDFLGSPELEVFCDMETSGG 169
Query: 278 GWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGP 337
GWT+IQ R+ G V F R W YKQGFG++ G++WLGN+ I +L+R P
Sbjct: 170 GWTIIQRRKSGLVSFYRDWKQYKQGFGSIR------------GDFWLGNEHIHRLSRQ-P 216
Query: 338 TELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTM 397
T L +EMEDW+G+ A Y F + NE N Y++ + Y G G N +
Sbjct: 217 TRLRVEMEDWEGNLRYAEYSHFVLGNELNSYRLFLGNYTGNVG-------------NDAL 263
Query: 398 TIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMA 457
HN FST D+DND L +C++ GG+WYN C +N NG YY G++
Sbjct: 264 QYHNNTAFSTKDKDNDNCL-----DKCAQLRKGGYWYNCCTDSNLNGVYYRLGEHN---- 314
Query: 458 KHGTDDGVVWMNWKGSWYSMRKMSMKIRP 486
KH DG+ W W GS YS++++ MKIRP
Sbjct: 315 KH--LDGITWYGWHGSTYSLKRVEMKIRP 341
>gi|29893555 angiopoietin-like 6 [Homo sapiens]
Length = 470
Score = 171 bits (433), Expect = 1e-42
Identities = 96/253 (37%), Positives = 133/253 (52%), Gaps = 38/253 (15%)
Query: 234 PVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFG 293
PV ++C E + G E S +Y ++ V V+C+ E GGWTVIQ RQDGSV+F
Sbjct: 253 PVGPWQDCAEARQAGHEQSGVYELRVGRHV--VSVWCEQQLEGGGWTVIQRRQDGSVNFF 310
Query: 294 RKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVK 353
W YK GFG GEYWLG + + QLT G ELL+ +EDW G +
Sbjct: 311 TTWQHYKAGFGRP------------DGEYWLGLEPVYQLTSRGDHELLVLLEDWGGRGAR 358
Query: 354 AHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDND 413
AHY GF+++ E++ Y++ + +Y G AG++L + HN FST DRD D
Sbjct: 359 AHYDGFSLEPESDHYRLRLGQYHGDAGDSL--------------SWHNDKPFSTVDRDRD 404
Query: 414 GWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGS 473
+ C+ GGWWY+ C +N NG ++ GG Y + DGV W ++G
Sbjct: 405 SY-----SGNCALYQRGGWWYHACAHSNLNGVWHHGGHY-----RSRYQDGVYWAEFRGG 454
Query: 474 WYSMRKMSMKIRP 486
YS+RK +M IRP
Sbjct: 455 AYSLRKAAMLIRP 467
>gi|169646749 angiopoietin 2 isoform b precursor [Homo sapiens]
Length = 495
Score = 169 bits (427), Expect = 7e-42
Identities = 105/342 (30%), Positives = 168/342 (49%), Gaps = 43/342 (12%)
Query: 152 KDLWQKRQKQVKDNENVVNEYSSELEKHQLYIDETVNSNIPTNLR-------VLRSILEN 204
K+ + +++ ++++++ S + EK QL + + ++I L V S+L+
Sbjct: 187 KNSFLEKKVLAMEDKHIIQLQSIKEEKDQLQVLVSKQNSIIEELEKKIVTATVNNSVLQK 246
Query: 205 LRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVK 264
+ + + +++ M + +S ++C E+ + G T+ +Y + +S +
Sbjct: 247 QQHDLMETVNNLLTMMSTSNSKDPTVAKEEQISFRDCAEVFKSGHTTNGIYTLTFPNSTE 306
Query: 265 PYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWL 324
+ YCDM GGWT+IQ R+DGSVDF R W YK GFGN + GEYWL
Sbjct: 307 EIKAYCDMEAGGGGWTIIQRREDGSVDFQRTWKEYKVGFGNPS------------GEYWL 354
Query: 325 GNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALM 384
GN+ +SQLT L I ++DW+G++ + Y F + +E Y+I + GTAG +
Sbjct: 355 GNEFVSQLTNQQRYVLKIHLKDWEGNEAYSLYEHFYLSSEELNYRIHLKGLTGTAGK--I 412
Query: 385 DGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNG 444
SQ G FST D DND + +CS+ GGWW++ C +N NG
Sbjct: 413 SSISQ-----------PGNDFSTKDGDNDKCIC-----KCSQMLTGGWWFDACGPSNLNG 456
Query: 445 RYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRP 486
YY Q T +G+ W WKGS YS++ +M IRP
Sbjct: 457 MYYPQRQNT------NKFNGIKWYYWKGSGYSLKATTMMIRP 492
>gi|7705276 angiopoietin 4 [Homo sapiens]
Length = 503
Score = 168 bits (425), Expect = 1e-41
Identities = 93/248 (37%), Positives = 134/248 (54%), Gaps = 36/248 (14%)
Query: 239 KECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDP 298
++C EI R G S +Y IQ ++ KP +V+CD+ + G WT+IQ R++G+V+F R W
Sbjct: 289 QDCAEIQRSGASASGVYTIQVSNATKPRKVFCDLQSSGGRWTLIQRRENGTVNFQRNWKD 348
Query: 299 YKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGG 358
YKQGFG+ A GE+WLGN+ + QLTR L +E++DW+G + A Y
Sbjct: 349 YKQGFGDPA------------GEHWLGNEVVHQLTRRAAYSLRVELQDWEGHEAYAQYEH 396
Query: 359 FTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTS 418
F + +E Y++SV Y G+AG S L+ +N + FST D DND L
Sbjct: 397 FHLGSENQLYRLSVVGYSGSAGR-----QSSLVLQNTS--------FSTLDSDNDHCLC- 442
Query: 419 DPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMR 478
+C++ GGWW++ C +N NG YY + M DG+ W +KG YS+R
Sbjct: 443 ----KCAQVMSGGWWFDACGLSNLNGVYYHAPDNKYKM------DGIRWHYFKGPSYSLR 492
Query: 479 KMSMKIRP 486
M IRP
Sbjct: 493 ASRMMIRP 500
>gi|5730075 fibrinogen-like 2 precursor [Homo sapiens]
Length = 439
Score = 168 bits (425), Expect = 1e-41
Identities = 110/338 (32%), Positives = 154/338 (45%), Gaps = 50/338 (14%)
Query: 157 KRQKQVKDNENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDV 216
K ++K+ + +N LEK L + + + + + L ++ +L K K S
Sbjct: 139 KLSSELKNAKEEINVLHGRLEKLNLVNMNNIENYVDSKVANLTFVVNSLDGKCSKCPSQE 198
Query: 217 SAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTEN 276
Q S + + K+C + G +SE Y + PD + VYCDM T
Sbjct: 199 QIQ----------SRPVQHLIYKDCSDYYAIGKRSSETYRVTPDPKNSSFEVYCDMETMG 248
Query: 277 GGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMG 336
GGWTV+Q R DGS +F R W YK GFGN L E+WLGNDKI LT+
Sbjct: 249 GGWTVLQARLDGSTNFTRTWQDYKAGFGN------------LRREFWLGNDKIHLLTKSK 296
Query: 337 PTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRT 396
L I++ED+ G ++ A Y F V NE KY++ V Y GTAG+AL
Sbjct: 297 EMILRIDLEDFNGVELYALYDQFYVANEFLKYRLHVGNYNGTAGDALRFNKHY------- 349
Query: 397 MTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDM 456
H+ FF+T D+DND + P C GWW++ C +AN NG+YY
Sbjct: 350 --NHDLKFFTTPDKDNDRY----PSGNCGLYYSSGWWFDACLSANLNGKYY-------HQ 396
Query: 457 AKHGTDDGVVWMNWKG------SWY--SMRKMSMKIRP 486
G +G+ W W G Y S ++ M IRP
Sbjct: 397 KYRGVRNGIFWGTWPGVSEAHPGGYKSSFKEAKMMIRP 434
>gi|169646754 angiopoietin 2 isoform c precursor [Homo sapiens]
Length = 444
Score = 167 bits (424), Expect = 2e-41
Identities = 108/345 (31%), Positives = 173/345 (50%), Gaps = 48/345 (13%)
Query: 152 KDLWQKRQKQVKDNENVVNEYSSELEKHQLYIDETVNSNIPTNL--RVLRSILENLRSKI 209
K+ + +++ ++++++ S + EK QL + + ++I L +++ + + N S +
Sbjct: 135 KNSFLEKKVLAMEDKHIIQLQSIKEEKDQLQVLVSKQNSIIEELEKKIVTATVNN--SVL 192
Query: 210 QKLESDVSAQMEYCRTPCTVSCNIP--------VVSGKECEEIIRKGGETSEMYLIQPDS 261
QK + D+ + T + S + +S ++C E+ + G T+ +Y + +
Sbjct: 193 QKQQHDLMETVNNLLTMMSTSNSAKDPTVAKEEQISFRDCAEVFKSGHTTNGIYTLTFPN 252
Query: 262 SVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGE 321
S + + YCDM GGWT+IQ R+DGSVDF R W YK GFGN + GE
Sbjct: 253 STEEIKAYCDMEAGGGGWTIIQRREDGSVDFQRTWKEYKVGFGNPS------------GE 300
Query: 322 YWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGN 381
YWLGN+ +SQLT L I ++DW+G++ + Y F + +E Y+I + GTAG
Sbjct: 301 YWLGNEFVSQLTNQQRYVLKIHLKDWEGNEAYSLYEHFYLSSEELNYRIHLKGLTGTAGK 360
Query: 382 ALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAAN 441
+ SQ G FST D DND + +CS+ GGWW++ C +N
Sbjct: 361 --ISSISQ-----------PGNDFSTKDGDNDKCIC-----KCSQMLTGGWWFDACGPSN 402
Query: 442 PNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRP 486
NG YY Q T +G+ W WKGS YS++ +M IRP
Sbjct: 403 LNGMYYPQRQNT------NKFNGIKWYYWKGSGYSLKATTMMIRP 441
>gi|4557315 angiopoietin 2 isoform a precursor [Homo sapiens]
Length = 496
Score = 167 bits (424), Expect = 2e-41
Identities = 108/345 (31%), Positives = 173/345 (50%), Gaps = 48/345 (13%)
Query: 152 KDLWQKRQKQVKDNENVVNEYSSELEKHQLYIDETVNSNIPTNL--RVLRSILENLRSKI 209
K+ + +++ ++++++ S + EK QL + + ++I L +++ + + N S +
Sbjct: 187 KNSFLEKKVLAMEDKHIIQLQSIKEEKDQLQVLVSKQNSIIEELEKKIVTATVNN--SVL 244
Query: 210 QKLESDVSAQMEYCRTPCTVSCNIP--------VVSGKECEEIIRKGGETSEMYLIQPDS 261
QK + D+ + T + S + +S ++C E+ + G T+ +Y + +
Sbjct: 245 QKQQHDLMETVNNLLTMMSTSNSAKDPTVAKEEQISFRDCAEVFKSGHTTNGIYTLTFPN 304
Query: 262 SVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGE 321
S + + YCDM GGWT+IQ R+DGSVDF R W YK GFGN + GE
Sbjct: 305 STEEIKAYCDMEAGGGGWTIIQRREDGSVDFQRTWKEYKVGFGNPS------------GE 352
Query: 322 YWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGN 381
YWLGN+ +SQLT L I ++DW+G++ + Y F + +E Y+I + GTAG
Sbjct: 353 YWLGNEFVSQLTNQQRYVLKIHLKDWEGNEAYSLYEHFYLSSEELNYRIHLKGLTGTAGK 412
Query: 382 ALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAAN 441
+ SQ G FST D DND + +CS+ GGWW++ C +N
Sbjct: 413 --ISSISQ-----------PGNDFSTKDGDNDKCIC-----KCSQMLTGGWWFDACGPSN 454
Query: 442 PNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRP 486
NG YY Q T +G+ W WKGS YS++ +M IRP
Sbjct: 455 LNGMYYPQRQNT------NKFNGIKWYYWKGSGYSLKATTMMIRP 493
>gi|223029463 fibrinogen C domain containing 1 [Homo sapiens]
Length = 461
Score = 165 bits (417), Expect = 1e-40
Identities = 90/253 (35%), Positives = 129/253 (50%), Gaps = 43/253 (16%)
Query: 239 KECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDP 298
++C +++ G + +Y + P ++VYCDM T+ GGWTV Q R+DGSV+F R WD
Sbjct: 242 RDCLDVLLSGQQDDGVYSVFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWDA 301
Query: 299 YKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGG 358
Y+ GFG L GE+WLG +I LT EL +++ED++ A YG
Sbjct: 302 YRDGFGR------------LTGEHWLGLKRIHALTTQAAYELHVDLEDFENGTAYARYGS 349
Query: 359 -----FTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDND 413
F+V E + Y ++V Y GTAG++L+ H+GM F+T DRD+D
Sbjct: 350 FGVGLFSVDPEEDGYPLTVADYSGTAGDSLLK--------------HSGMRFTTKDRDSD 395
Query: 414 GWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGS 473
C+ G WWY CH +N NG+Y G ++ DGV W +W G
Sbjct: 396 -----HSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASY-------ADGVEWSSWTGW 443
Query: 474 WYSMRKMSMKIRP 486
YS++ MKIRP
Sbjct: 444 QYSLKFSEMKIRP 456
>gi|223029461 fibrinogen C domain containing 1 [Homo sapiens]
Length = 461
Score = 165 bits (417), Expect = 1e-40
Identities = 90/253 (35%), Positives = 129/253 (50%), Gaps = 43/253 (16%)
Query: 239 KECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDP 298
++C +++ G + +Y + P ++VYCDM T+ GGWTV Q R+DGSV+F R WD
Sbjct: 242 RDCLDVLLSGQQDDGVYSVFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWDA 301
Query: 299 YKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGG 358
Y+ GFG L GE+WLG +I LT EL +++ED++ A YG
Sbjct: 302 YRDGFGR------------LTGEHWLGLKRIHALTTQAAYELHVDLEDFENGTAYARYGS 349
Query: 359 -----FTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDND 413
F+V E + Y ++V Y GTAG++L+ H+GM F+T DRD+D
Sbjct: 350 FGVGLFSVDPEEDGYPLTVADYSGTAGDSLLK--------------HSGMRFTTKDRDSD 395
Query: 414 GWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGS 473
C+ G WWY CH +N NG+Y G ++ DGV W +W G
Sbjct: 396 -----HSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASY-------ADGVEWSSWTGW 443
Query: 474 WYSMRKMSMKIRP 486
YS++ MKIRP
Sbjct: 444 QYSLKFSEMKIRP 456
>gi|20532340 angiopoietin 1 [Homo sapiens]
Length = 498
Score = 164 bits (416), Expect = 1e-40
Identities = 88/248 (35%), Positives = 132/248 (53%), Gaps = 36/248 (14%)
Query: 239 KECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDP 298
++C ++ + G S +Y I ++ +P +V+C+M+ GGWTVIQ+R+DGS+DF R W
Sbjct: 284 RDCADVYQAGFNKSGIYTIYINNMPEPKKVFCNMDVNGGGWTVIQHREDGSLDFQRGWKE 343
Query: 299 YKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGG 358
YK GFGN + GEYWLGN+ I +T L IE+ DW+G++ + Y
Sbjct: 344 YKMGFGNPS------------GEYWLGNEFIFAITSQRQYMLRIELMDWEGNRAYSQYDR 391
Query: 359 FTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTS 418
F + NE Y++ + + GTAG ++ I +G FST D DND +
Sbjct: 392 FHIGNEKQNYRLYLKGHTGTAG-------------KQSSLILHGADFSTKDADNDNCMC- 437
Query: 419 DPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMR 478
+C+ GGWW++ C +N NG +Y GQ HG +G+ W +KG YS+R
Sbjct: 438 ----KCALMLTGGWWFDACGPSNLNGMFYTAGQ------NHGKLNGIKWHYFKGPSYSLR 487
Query: 479 KMSMKIRP 486
+M IRP
Sbjct: 488 STTMMIRP 495
>gi|8051584 ficolin 1 precursor [Homo sapiens]
Length = 326
Score = 160 bits (406), Expect = 2e-39
Identities = 95/250 (38%), Positives = 132/250 (52%), Gaps = 42/250 (16%)
Query: 239 KECEEIIRKGGETSEMYLIQ-PDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWD 297
+ C++++ +G S + I PD +P V CDM+T+ GGWTV Q R DGSVDF R W
Sbjct: 116 RNCKDLLDRGYFLSGWHTIYLPDC--RPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWA 173
Query: 298 PYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYG 357
YKQGFG+ GE+WLGND I LT G +EL +++ D++G+ A Y
Sbjct: 174 AYKQGFGSQL------------GEFWLGNDNIHALTAQGSSELRVDLVDFEGNHQFAKYK 221
Query: 358 GFTVQNEANKYQISVNKY-RGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWL 416
F V +EA KY++ + + G+AGN+L T HN FFST D+DND
Sbjct: 222 SFKVADEAEKYKLVLGAFVGGSAGNSL--------------TGHNNNFFSTKDQDND--- 264
Query: 417 TSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYS 476
C+++ G WWY CHA+N NG Y G ++ +G+ W KG YS
Sbjct: 265 --VSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESY-------ANGINWSAAKGYKYS 315
Query: 477 MRKMSMKIRP 486
+ MK+RP
Sbjct: 316 YKVSEMKVRP 325
>gi|62988324 tenascin N [Homo sapiens]
Length = 1299
Score = 157 bits (398), Expect = 2e-38
Identities = 96/265 (36%), Positives = 132/265 (49%), Gaps = 47/265 (17%)
Query: 225 TPCTVSCNIPVVSGKECEEIIRKGGETSEMYLI--QPDSSVKPYRVYCDMNTENGGWTVI 282
T TV P S +C ++ + S +Y I D+S +P +VYCDM T+ GGW V
Sbjct: 1056 TLSTVGARFPHPS--DCSQVQQNSNAASGLYTIYLHGDAS-RPLQVYCDMETDGGGWIVF 1112
Query: 283 QNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLI 342
Q R G +DF ++W Y +GFG+ E+WLG DK+ LT P +
Sbjct: 1113 QRRNTGQLDFFKRWRSYVEGFGDPMK------------EFWLGLDKLHNLTTGTPARYEV 1160
Query: 343 EME-DWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHN 401
++ + A Y F V + +Y+++V KYRGTAG+AL T HN
Sbjct: 1161 RVDLQTANESAYAIYDFFQVASSKERYKLTVGKYRGTAGDAL--------------TYHN 1206
Query: 402 GMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGT 461
G F+T+DRDND L++ C+ GGWWY CH ANPNGRY KH
Sbjct: 1207 GWKFTTFDRDNDIALSN-----CALTHHGGWWYKNCHLANPNGRY--------GETKH-- 1251
Query: 462 DDGVVWMNWKGSWYSMRKMSMKIRP 486
+GV W WKG +S+ + +KIRP
Sbjct: 1252 SEGVNWEPWKGHEFSIPYVELKIRP 1276
>gi|8051586 ficolin 2 isoform b precursor [Homo sapiens]
Length = 275
Score = 155 bits (393), Expect = 6e-38
Identities = 97/257 (37%), Positives = 135/257 (52%), Gaps = 45/257 (17%)
Query: 234 PVVSG-KECEEIIRKGGETSEMYLIQ-PDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVD 291
P ++G + C++++ +G S + I PD +P V CDM+T+ GGWTV Q R DGSVD
Sbjct: 59 PCLTGPRTCKDLLDRGHFLSGWHTIYLPDC--RPLTVLCDMDTDGGGWTVFQRRVDGSVD 116
Query: 292 FGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDK 351
F R W YKQGFG+ GE+WLGND I LT G +EL +++ D++ +
Sbjct: 117 FYRDWATYKQGFGSRL------------GEFWLGNDNIHALTAQGTSELRVDLVDFEDNY 164
Query: 352 VKAHYGGFTVQNEANKYQISVNKY-RGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDR 410
A Y F V +EA KY + + + G+AG++L T HN FST D+
Sbjct: 165 QFAKYRSFKVADEAEKYNLVLGAFVEGSAGDSL--------------TFHNNQSFSTKDQ 210
Query: 411 DNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGT-DDGVVWMN 469
DND L + C+ G WWY CH +N NGRY G HG+ +G+ W +
Sbjct: 211 DND--LNTG---NCAVMFQGAWWYKNCHVSNLNGRYLRG--------THGSFANGINWKS 257
Query: 470 WKGSWYSMRKMSMKIRP 486
KG YS + MK+RP
Sbjct: 258 GKGYNYSYKVSEMKVRP 274
>gi|61744445 ficolin 2 isoform a precursor [Homo sapiens]
Length = 313
Score = 155 bits (393), Expect = 6e-38
Identities = 97/257 (37%), Positives = 135/257 (52%), Gaps = 45/257 (17%)
Query: 234 PVVSG-KECEEIIRKGGETSEMYLIQ-PDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVD 291
P ++G + C++++ +G S + I PD +P V CDM+T+ GGWTV Q R DGSVD
Sbjct: 97 PCLTGPRTCKDLLDRGHFLSGWHTIYLPDC--RPLTVLCDMDTDGGGWTVFQRRVDGSVD 154
Query: 292 FGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDK 351
F R W YKQGFG+ GE+WLGND I LT G +EL +++ D++ +
Sbjct: 155 FYRDWATYKQGFGSRL------------GEFWLGNDNIHALTAQGTSELRVDLVDFEDNY 202
Query: 352 VKAHYGGFTVQNEANKYQISVNKY-RGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDR 410
A Y F V +EA KY + + + G+AG++L T HN FST D+
Sbjct: 203 QFAKYRSFKVADEAEKYNLVLGAFVEGSAGDSL--------------TFHNNQSFSTKDQ 248
Query: 411 DNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGT-DDGVVWMN 469
DND L + C+ G WWY CH +N NGRY G HG+ +G+ W +
Sbjct: 249 DND--LNTG---NCAVMFQGAWWYKNCHVSNLNGRYLRG--------THGSFANGINWKS 295
Query: 470 WKGSWYSMRKMSMKIRP 486
KG YS + MK+RP
Sbjct: 296 GKGYNYSYKVSEMKVRP 312
>gi|27754778 ficolin 3 isoform 2 precursor [Homo sapiens]
Length = 288
Score = 155 bits (392), Expect = 8e-38
Identities = 89/249 (35%), Positives = 130/249 (52%), Gaps = 42/249 (16%)
Query: 239 KECEEIIRKGGETSEMY-LIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWD 297
+ C E++ +G S Y L P+ P V+CDM+TE GGW V Q RQDGSVDF R W
Sbjct: 80 RNCRELLSQGATLSGWYHLCLPEGRALP--VFCDMDTEGGGWLVFQRRQDGSVDFFRSWS 137
Query: 298 PYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYG 357
Y+ GFGN + E+WLGN+ + QLT G EL +E+ED+ G++ AHY
Sbjct: 138 SYRAGFGNQES------------EFWLGNENLHQLTLQGNWELRVELEDFNGNRTFAHYA 185
Query: 358 GFTVQNEANKYQISVNKY-RGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWL 416
F + E + YQ+++ K+ GTAG++L ++H+G F+TYD D+D
Sbjct: 186 TFRLLGEVDHYQLALGKFSEGTAGDSL--------------SLHSGRPFTTYDADHD--- 228
Query: 417 TSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYS 476
C+ G WWY C+ +N NGRY + A H G+ W + +G +
Sbjct: 229 --SSNSNCAVIVHGAWWYASCYRSNLNGRY-----AVSEAAAH--KYGIDWASGRGVGHP 279
Query: 477 MRKMSMKIR 485
R++ M +R
Sbjct: 280 YRRVRMMLR 288
>gi|27754776 ficolin 3 isoform 1 precursor [Homo sapiens]
Length = 299
Score = 155 bits (392), Expect = 8e-38
Identities = 89/249 (35%), Positives = 130/249 (52%), Gaps = 42/249 (16%)
Query: 239 KECEEIIRKGGETSEMY-LIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWD 297
+ C E++ +G S Y L P+ P V+CDM+TE GGW V Q RQDGSVDF R W
Sbjct: 91 RNCRELLSQGATLSGWYHLCLPEGRALP--VFCDMDTEGGGWLVFQRRQDGSVDFFRSWS 148
Query: 298 PYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYG 357
Y+ GFGN + E+WLGN+ + QLT G EL +E+ED+ G++ AHY
Sbjct: 149 SYRAGFGNQES------------EFWLGNENLHQLTLQGNWELRVELEDFNGNRTFAHYA 196
Query: 358 GFTVQNEANKYQISVNKY-RGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWL 416
F + E + YQ+++ K+ GTAG++L ++H+G F+TYD D+D
Sbjct: 197 TFRLLGEVDHYQLALGKFSEGTAGDSL--------------SLHSGRPFTTYDADHD--- 239
Query: 417 TSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYS 476
C+ G WWY C+ +N NGRY + A H G+ W + +G +
Sbjct: 240 --SSNSNCAVIVHGAWWYASCYRSNLNGRY-----AVSEAAAH--KYGIDWASGRGVGHP 290
Query: 477 MRKMSMKIR 485
R++ M +R
Sbjct: 291 YRRVRMMLR 299
>gi|157384973 tenascin R [Homo sapiens]
Length = 1358
Score = 152 bits (385), Expect = 5e-37
Identities = 87/250 (34%), Positives = 128/250 (51%), Gaps = 43/250 (17%)
Query: 239 KECEEIIRKGGETSEMYLIQPDSSV-KPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWD 297
++C + + G S +Y I + + + +VYCDM T+ GGW V Q RQ+G DF RKW
Sbjct: 1136 QDCAQHLMNGDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWA 1195
Query: 298 PYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYG 357
Y+ GFGNV E+WLG D I ++T G EL ++M D + + A Y
Sbjct: 1196 DYRVGFGNV------------EDEFWLGLDNIHRITSQGRYELRVDMRDGQ-EAAFASYD 1242
Query: 358 GFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLT 417
F+V++ N Y++ + Y GTAG++L + H G FST DRDND +T
Sbjct: 1243 RFSVEDSRNLYKLRIGSYNGTAGDSL--------------SYHQGRPFSTEDRDNDVAVT 1288
Query: 418 SDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSM 477
+ C+ G WWY CH N NG+Y ++H G+ W +WKG +S+
Sbjct: 1289 N-----CAMSYKGAWWYKNCHRTNLNGKY--------GESRH--SQGINWYHWKGHEFSI 1333
Query: 478 RKMSMKIRPF 487
+ MK+RP+
Sbjct: 1334 PFVEMKMRPY 1343
Score = 38.5 bits (88), Expect = 0.014
Identities = 33/135 (24%), Positives = 55/135 (40%), Gaps = 17/135 (12%)
Query: 107 PTGCQLQEALLQQERPIRNSVDELNN--NVEAVSQTSSSSFQYMYLLK---------DLW 155
P+ CQL+ + ER R SV+E N S+ F ++Y + L
Sbjct: 28 PSECQLE---VTTERVQRQSVEEEGGIANYNTSSKEQPVVFNHVYNINVPLDNLCSSGLE 84
Query: 156 QKRQKQVKDNENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRS---ILENLRSKIQKL 212
+++V + + EY + H+ + T N P S +L+ L S+I+ L
Sbjct: 85 ASAEQEVSAEDETLAEYMGQTSDHESQVTFTHRINFPKKACPCASSAQVLQELLSRIEML 144
Query: 213 ESDVSAQMEYCRTPC 227
E +VS + C C
Sbjct: 145 EREVSVLRDQCNANC 159
>gi|23111005 microfibrillar-associated protein 4 [Homo sapiens]
Length = 255
Score = 145 bits (367), Expect = 6e-35
Identities = 82/246 (33%), Positives = 123/246 (50%), Gaps = 32/246 (13%)
Query: 240 ECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPY 299
+C++I +G ++ +YLI P P V+CDM TE G WTV Q R +GSV F R W+ Y
Sbjct: 40 DCDDIYAQGYQSDGVYLIYPSGPSVPVPVFCDMTTEGGKWTVFQKRFNGSVSFFRGWNDY 99
Query: 300 KQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGF 359
K GFG GEYWLG + LT EL +++ED++ + A Y F
Sbjct: 100 KLGFGRA------------DGEYWLGLQNMHLLTLKQKYELRVDLEDFENNTAYAKYADF 147
Query: 360 TVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSD 419
++ A +S + G L + G +++ H+G FST+DRD D ++
Sbjct: 148 SISPNA----VSAEE----DGYTLFVAGFEDGGAGDSLSYHSGQKFSTFDRDQDLFV--- 196
Query: 420 PRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRK 479
+ C+ G +W+ CH AN NG Y G ++ +G+ W WKG +YS+++
Sbjct: 197 --QNCAALSSGAFWFRSCHFANLNGFYLGGSHLSY-------ANGINWAQWKGFYYSLKR 247
Query: 480 MSMKIR 485
MKIR
Sbjct: 248 TEMKIR 253
>gi|20665034 tenascin XB isoform 2 [Homo sapiens]
Length = 673
Score = 142 bits (357), Expect = 9e-34
Identities = 84/250 (33%), Positives = 119/250 (47%), Gaps = 45/250 (18%)
Query: 239 KECEEIIRKGGETSEMYLIQPDSS-VKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWD 297
++C E ++ G S I + + +P V+CDM T+ GGW V Q R DG DF R W+
Sbjct: 457 RDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWE 516
Query: 298 PYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDK-VKAHY 356
Y GFGN++ GE+WLGN+ + LT+ G + +++ GD+ V A Y
Sbjct: 517 DYAHGFGNIS------------GEFWLGNEALHSLTQAGDYSMRVDLR--AGDEAVFAQY 562
Query: 357 GGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWL 416
F V + A Y++ + Y GTAG+ +M+ H+G FS DRD + L
Sbjct: 563 DSFHVDSAAEYYRLHLEGYHGTAGD--------------SMSYHSGSVFSARDRDPNSLL 608
Query: 417 TSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYS 476
S C+ G WWY CH AN NG Y GV W +WKG +S
Sbjct: 609 IS-----CAVSYRGAWWYRNCHYANLNGLY----------GSTVDHQGVSWYHWKGFEFS 653
Query: 477 MRKMSMKIRP 486
+ MK+RP
Sbjct: 654 VPFTEMKLRP 663
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 142 bits (357), Expect = 9e-34
Identities = 84/250 (33%), Positives = 119/250 (47%), Gaps = 45/250 (18%)
Query: 239 KECEEIIRKGGETSEMYLIQPDSS-VKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWD 297
++C E ++ G S I + + +P V+CDM T+ GGW V Q R DG DF R W+
Sbjct: 4026 RDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWE 4085
Query: 298 PYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDK-VKAHY 356
Y GFGN++ GE+WLGN+ + LT+ G + +++ GD+ V A Y
Sbjct: 4086 DYAHGFGNIS------------GEFWLGNEALHSLTQAGDYSMRVDLR--AGDEAVFAQY 4131
Query: 357 GGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWL 416
F V + A Y++ + Y GTAG+ +M+ H+G FS DRD + L
Sbjct: 4132 DSFHVDSAAEYYRLHLEGYHGTAGD--------------SMSYHSGSVFSARDRDPNSLL 4177
Query: 417 TSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYS 476
S C+ G WWY CH AN NG Y GV W +WKG +S
Sbjct: 4178 IS-----CAVSYRGAWWYRNCHYANLNGLY----------GSTVDHQGVSWYHWKGFEFS 4222
Query: 477 MRKMSMKIRP 486
+ MK+RP
Sbjct: 4223 VPFTEMKLRP 4232
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,691,897
Number of Sequences: 37866
Number of extensions: 1000091
Number of successful extensions: 4003
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 66
Number of HSP's that attempted gapping in prelim test: 3735
Number of HSP's gapped (non-prelim): 185
length of query: 491
length of database: 18,247,518
effective HSP length: 106
effective length of query: 385
effective length of database: 14,233,722
effective search space: 5479982970
effective search space used: 5479982970
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.