Guide to the Human Genome
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Search of human proteins with 7019377

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7019377 FtsJ homolog 2 [Homo sapiens]
         (246 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7019377 FtsJ homolog 2 [Homo sapiens]                              499   e-142
gi|29029591 FtsJ homolog 1 isoform b [Homo sapiens]                   120   1e-27
gi|29029589 FtsJ homolog 1 isoform b [Homo sapiens]                   120   1e-27
gi|7110661 FtsJ homolog 1 isoform a [Homo sapiens]                    120   1e-27
gi|194097365 FtsJ homolog 3 [Homo sapiens]                            102   3e-22
gi|153792086 FtsJ methyltransferase domain containing 1 [Homo sa...    32   0.66 
gi|153791865 FtsJ methyltransferase domain containing 1 [Homo sa...    32   0.66 
gi|10862701 ret proto-oncogene isoform c [Homo sapiens]                28   7.3  
gi|10862703 ret proto-oncogene isoform a [Homo sapiens]                28   7.3  
gi|95089461 discs large homolog 5 [Homo sapiens]                       28   7.3  
gi|209862791 zinc finger protein 90 [Homo sapiens]                     28   7.3  
gi|116812644 PBX/knotted 1 homeobox 2 [Homo sapiens]                   28   7.3  
gi|25286703 hypothetical protein LOC90231 [Homo sapiens]               28   7.3  
gi|4506581 retinitis pigmentosa GTPase regulator isoform A [Homo...    28   9.5  
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    28   9.5  
gi|217035158 zinc finger protein 780A isoform b [Homo sapiens]         28   9.5  
gi|217035160 zinc finger protein 780A isoform b [Homo sapiens]         28   9.5  
gi|217035156 zinc finger protein 780A isoform a [Homo sapiens]         28   9.5  
gi|62865883 zinc finger protein 2 isoform b [Homo sapiens]             28   9.5  
gi|62865881 zinc finger protein 2 isoform a [Homo sapiens]             28   9.5  

>gi|7019377 FtsJ homolog 2 [Homo sapiens]
          Length = 246

 Score =  499 bits (1285), Expect = e-142
 Identities = 246/246 (100%), Positives = 246/246 (100%)

Query: 1   MAGYLKLVCVSFQRQGFHTVGSRCKNRTGAEHLWLTRHLRDPFVKAAKVESYRCRSAFKL 60
           MAGYLKLVCVSFQRQGFHTVGSRCKNRTGAEHLWLTRHLRDPFVKAAKVESYRCRSAFKL
Sbjct: 1   MAGYLKLVCVSFQRQGFHTVGSRCKNRTGAEHLWLTRHLRDPFVKAAKVESYRCRSAFKL 60

Query: 61  LEVNERHQILRPGLRVLDCGAAPGAWSQVAVQKVNAAGTDPSSPVGFVLGVDLLHIFPLE 120
           LEVNERHQILRPGLRVLDCGAAPGAWSQVAVQKVNAAGTDPSSPVGFVLGVDLLHIFPLE
Sbjct: 61  LEVNERHQILRPGLRVLDCGAAPGAWSQVAVQKVNAAGTDPSSPVGFVLGVDLLHIFPLE 120

Query: 121 GATFLCPADVTDPRTSQRILEVLPGRRADVILSDMAPNATGFRDLDHDRLISLCLTLLSV 180
           GATFLCPADVTDPRTSQRILEVLPGRRADVILSDMAPNATGFRDLDHDRLISLCLTLLSV
Sbjct: 121 GATFLCPADVTDPRTSQRILEVLPGRRADVILSDMAPNATGFRDLDHDRLISLCLTLLSV 180

Query: 181 TPDILQPGGTFLCKTWAGSQSRRLQRRLTEEFQNVRIIKPEASRKESSEVYFLATQYHGR 240
           TPDILQPGGTFLCKTWAGSQSRRLQRRLTEEFQNVRIIKPEASRKESSEVYFLATQYHGR
Sbjct: 181 TPDILQPGGTFLCKTWAGSQSRRLQRRLTEEFQNVRIIKPEASRKESSEVYFLATQYHGR 240

Query: 241 KGTVKQ 246
           KGTVKQ
Sbjct: 241 KGTVKQ 246


>gi|29029591 FtsJ homolog 1 isoform b [Homo sapiens]
          Length = 327

 Score =  120 bits (301), Expect = 1e-27
 Identities = 70/205 (34%), Positives = 109/205 (53%), Gaps = 7/205 (3%)

Query: 40  RDPFVKAAKVESYRCRSAFKLLEVNERHQILRPGLRVLDCGAAPGAWSQVAVQKVNAAGT 99
           RD + + AK   +R RSAFKLL++++  Q+ +   R +D  AAPG+WSQV  QK+   G+
Sbjct: 9   RDVYYRLAKENGWRARSAFKLLQLDKEFQLFQGVTRAVDLCAAPGSWSQVLSQKIGGQGS 68

Query: 100 DPSSPVGFVLGVDLLHIFPLEGATFLCPADVTDPRTSQRILEVLPGRRADVILSDMAPNA 159
                 G V+ VDL  + PL G   +   D+T   T++ I++   G  AD+++ D AP+ 
Sbjct: 69  ------GHVVAVDLQAMAPLPGVVQI-QGDITQLSTAKEIIQHFKGCPADLVVCDGAPDV 121

Query: 160 TGFRDLDHDRLISLCLTLLSVTPDILQPGGTFLCKTWAGSQSRRLQRRLTEEFQNVRIIK 219
           TG  D+D      L L  L++   +L+PGG F+ K + G     L  +L   F +V   K
Sbjct: 122 TGLHDVDEYMQAQLLLAALNIATHVLKPGGCFVAKIFRGRDVTLLYSQLQVFFSSVLCAK 181

Query: 220 PEASRKESSEVYFLATQYHGRKGTV 244
           P +SR  S E + +   Y   +G +
Sbjct: 182 PRSSRNSSIEAFAVCQGYDPPEGFI 206


>gi|29029589 FtsJ homolog 1 isoform b [Homo sapiens]
          Length = 327

 Score =  120 bits (301), Expect = 1e-27
 Identities = 70/205 (34%), Positives = 109/205 (53%), Gaps = 7/205 (3%)

Query: 40  RDPFVKAAKVESYRCRSAFKLLEVNERHQILRPGLRVLDCGAAPGAWSQVAVQKVNAAGT 99
           RD + + AK   +R RSAFKLL++++  Q+ +   R +D  AAPG+WSQV  QK+   G+
Sbjct: 9   RDVYYRLAKENGWRARSAFKLLQLDKEFQLFQGVTRAVDLCAAPGSWSQVLSQKIGGQGS 68

Query: 100 DPSSPVGFVLGVDLLHIFPLEGATFLCPADVTDPRTSQRILEVLPGRRADVILSDMAPNA 159
                 G V+ VDL  + PL G   +   D+T   T++ I++   G  AD+++ D AP+ 
Sbjct: 69  ------GHVVAVDLQAMAPLPGVVQI-QGDITQLSTAKEIIQHFKGCPADLVVCDGAPDV 121

Query: 160 TGFRDLDHDRLISLCLTLLSVTPDILQPGGTFLCKTWAGSQSRRLQRRLTEEFQNVRIIK 219
           TG  D+D      L L  L++   +L+PGG F+ K + G     L  +L   F +V   K
Sbjct: 122 TGLHDVDEYMQAQLLLAALNIATHVLKPGGCFVAKIFRGRDVTLLYSQLQVFFSSVLCAK 181

Query: 220 PEASRKESSEVYFLATQYHGRKGTV 244
           P +SR  S E + +   Y   +G +
Sbjct: 182 PRSSRNSSIEAFAVCQGYDPPEGFI 206


>gi|7110661 FtsJ homolog 1 isoform a [Homo sapiens]
          Length = 329

 Score =  120 bits (301), Expect = 1e-27
 Identities = 70/205 (34%), Positives = 109/205 (53%), Gaps = 7/205 (3%)

Query: 40  RDPFVKAAKVESYRCRSAFKLLEVNERHQILRPGLRVLDCGAAPGAWSQVAVQKVNAAGT 99
           RD + + AK   +R RSAFKLL++++  Q+ +   R +D  AAPG+WSQV  QK+   G+
Sbjct: 9   RDVYYRLAKENGWRARSAFKLLQLDKEFQLFQGVTRAVDLCAAPGSWSQVLSQKIGGQGS 68

Query: 100 DPSSPVGFVLGVDLLHIFPLEGATFLCPADVTDPRTSQRILEVLPGRRADVILSDMAPNA 159
                 G V+ VDL  + PL G   +   D+T   T++ I++   G  AD+++ D AP+ 
Sbjct: 69  ------GHVVAVDLQAMAPLPGVVQI-QGDITQLSTAKEIIQHFKGCPADLVVCDGAPDV 121

Query: 160 TGFRDLDHDRLISLCLTLLSVTPDILQPGGTFLCKTWAGSQSRRLQRRLTEEFQNVRIIK 219
           TG  D+D      L L  L++   +L+PGG F+ K + G     L  +L   F +V   K
Sbjct: 122 TGLHDVDEYMQAQLLLAALNIATHVLKPGGCFVAKIFRGRDVTLLYSQLQVFFSSVLCAK 181

Query: 220 PEASRKESSEVYFLATQYHGRKGTV 244
           P +SR  S E + +   Y   +G +
Sbjct: 182 PRSSRNSSIEAFAVCQGYDPPEGFI 206


>gi|194097365 FtsJ homolog 3 [Homo sapiens]
          Length = 847

 Score =  102 bits (254), Expect = 3e-22
 Identities = 68/192 (35%), Positives = 97/192 (50%), Gaps = 9/192 (4%)

Query: 40  RDPFVKAAKVESYRCRSAFKLLEVNERHQILRPGLRVLDCGAAPGAWSQVAVQKVNAAGT 99
           RD F   AK   YR RSAFKL+++N R Q L+    +LD  AAPG W QVA + +  +  
Sbjct: 12  RDKFYHLAKETGYRSRSAFKLIQLNRRFQFLQKARALLDLCAAPGGWLQVAAKFMPVS-- 69

Query: 100 DPSSPVGFVLGVDLLHIFPLEGATFLCPADVTDPRTSQRILEVLPGRRADVILSDMAPNA 159
                   ++GVDL+ I PL     L   D+T  R  Q + + L   + DV+L+D APN 
Sbjct: 70  ------SLIVGVDLVPIKPLPNVVTL-QQDITTERCRQALRKELKTWKVDVVLNDGAPNV 122

Query: 160 TGFRDLDHDRLISLCLTLLSVTPDILQPGGTFLCKTWAGSQSRRLQRRLTEEFQNVRIIK 219
                 D      L L  L +  D L  GG+F+ K +     + L     + F+ V+  K
Sbjct: 123 GASWVHDAYSQAHLTLMALRLACDFLARGGSFITKVFRSRDYQPLLWIFQQLFRRVQATK 182

Query: 220 PEASRKESSEVY 231
           P+ASR ES+E++
Sbjct: 183 PQASRHESAEIF 194


>gi|153792086 FtsJ methyltransferase domain containing 1 [Homo
           sapiens]
          Length = 770

 Score = 31.6 bits (70), Expect = 0.66
 Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 2/56 (3%)

Query: 188 GGTFLCKTWAGSQ--SRRLQRRLTEEFQNVRIIKPEASRKESSEVYFLATQYHGRK 241
           GG+F+ K +   +  S  L   L   F  V + KP  S+  +SEVY +   Y GR+
Sbjct: 269 GGSFVLKMFTMFEHCSINLMYLLNCCFDQVHVFKPATSKAGNSEVYVVCLHYKGRE 324


>gi|153791865 FtsJ methyltransferase domain containing 1 [Homo
           sapiens]
          Length = 770

 Score = 31.6 bits (70), Expect = 0.66
 Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 2/56 (3%)

Query: 188 GGTFLCKTWAGSQ--SRRLQRRLTEEFQNVRIIKPEASRKESSEVYFLATQYHGRK 241
           GG+F+ K +   +  S  L   L   F  V + KP  S+  +SEVY +   Y GR+
Sbjct: 269 GGSFVLKMFTMFEHCSINLMYLLNCCFDQVHVFKPATSKAGNSEVYVVCLHYKGRE 324


>gi|10862701 ret proto-oncogene isoform c [Homo sapiens]
          Length = 1072

 Score = 28.1 bits (61), Expect = 7.3
 Identities = 13/36 (36%), Positives = 16/36 (44%)

Query: 98  GTDPSSPVGFVLGVDLLHIFPLEGATFLCPADVTDP 133
           G +P  P G   G    + FP E   F  P D+ DP
Sbjct: 593 GHEPGEPRGIKAGYGTCNCFPEEEKCFCEPEDIQDP 628


>gi|10862703 ret proto-oncogene isoform a [Homo sapiens]
          Length = 1114

 Score = 28.1 bits (61), Expect = 7.3
 Identities = 13/36 (36%), Positives = 16/36 (44%)

Query: 98  GTDPSSPVGFVLGVDLLHIFPLEGATFLCPADVTDP 133
           G +P  P G   G    + FP E   F  P D+ DP
Sbjct: 593 GHEPGEPRGIKAGYGTCNCFPEEEKCFCEPEDIQDP 628


>gi|95089461 discs large homolog 5 [Homo sapiens]
          Length = 1919

 Score = 28.1 bits (61), Expect = 7.3
 Identities = 21/90 (23%), Positives = 38/90 (42%), Gaps = 2/90 (2%)

Query: 58  FKLLEVNERHQILRPGLRVLDCGAAPGAWSQVAVQKVNAAGTDPSSPVGFVLGVDLLHIF 117
           F L++V  R  +L     V  CG    +  +   +  N+ GT P + +      + L ++
Sbjct: 905 FGLVDVRGRRPLLPFETEVGPCGVGEASLDKADSEGSNSGGTWPKAMLSSTAVPEKLSVY 964

Query: 118 --PLEGATFLCPADVTDPRTSQRILEVLPG 145
             P +  +   P     P+T  +I  +LPG
Sbjct: 965 KKPKQRKSIFDPNTFKRPQTPPKIDYLLPG 994


>gi|209862791 zinc finger protein 90 [Homo sapiens]
          Length = 601

 Score = 28.1 bits (61), Expect = 7.3
 Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 3/51 (5%)

Query: 54  CRSAFKLLEVNERHQILRPGLRVL---DCGAAPGAWSQVAVQKVNAAGTDP 101
           C  AFK   V  +H+I+  G +     +CG A    SQ+   K++  G  P
Sbjct: 514 CGKAFKRSSVLSKHKIIHTGAKPYKCEECGKAFKRSSQLTSHKISHTGEKP 564


>gi|116812644 PBX/knotted 1 homeobox 2 [Homo sapiens]
          Length = 472

 Score = 28.1 bits (61), Expect = 7.3
 Identities = 19/66 (28%), Positives = 29/66 (43%), Gaps = 5/66 (7%)

Query: 25  KNRTGAEHLWLTRHLRDPFVKAAKVESYRCRSAFKLLEVNE-----RHQILRPGLRVLDC 79
           K+ T     WL +HL  P+    +      ++   LL+VN      R +IL+P L   + 
Sbjct: 297 KHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASNP 356

Query: 80  GAAPGA 85
             AP A
Sbjct: 357 DPAPKA 362


>gi|25286703 hypothetical protein LOC90231 [Homo sapiens]
          Length = 634

 Score = 28.1 bits (61), Expect = 7.3
 Identities = 28/86 (32%), Positives = 34/86 (39%), Gaps = 14/86 (16%)

Query: 30  AEHLWLTRHLRDPFVKAAKVESYRCRSAFKLLEVNERHQILRPGL----RVLDCGA-APG 84
           A  LW+T   R+P V    V   + R    L E  E   +LR GL    R L  G+  PG
Sbjct: 104 ANRLWVTPGEREPAVAPDFVPFVQLRPLSALAEAGEAVLLLREGLLRRVRCLQLGSPGPG 163

Query: 85  AWSQVAVQKVNAAGTDPSSPVGFVLG 110
                      AAG  P+S  G   G
Sbjct: 164 P---------VAAGPGPASVSGLAAG 180


>gi|4506581 retinitis pigmentosa GTPase regulator isoform A [Homo
           sapiens]
          Length = 815

 Score = 27.7 bits (60), Expect = 9.5
 Identities = 15/65 (23%), Positives = 29/65 (44%)

Query: 156 APNATGFRDLDHDRLISLCLTLLSVTPDILQPGGTFLCKTWAGSQSRRLQRRLTEEFQNV 215
           AP+    ++++ D +   CL++ +  P      G  L +T +    RR + R  + F   
Sbjct: 366 APHRGVAKEIEFDEINDTCLSVATFLPYSSLTSGNVLQRTLSARMRRRERERSPDSFSMR 425

Query: 216 RIIKP 220
           R + P
Sbjct: 426 RTLPP 430


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
           sapiens]
          Length = 1152

 Score = 27.7 bits (60), Expect = 9.5
 Identities = 15/65 (23%), Positives = 29/65 (44%)

Query: 156 APNATGFRDLDHDRLISLCLTLLSVTPDILQPGGTFLCKTWAGSQSRRLQRRLTEEFQNV 215
           AP+    ++++ D +   CL++ +  P      G  L +T +    RR + R  + F   
Sbjct: 366 APHRGVAKEIEFDEINDTCLSVATFLPYSSLTSGNVLQRTLSARMRRRERERSPDSFSMR 425

Query: 216 RIIKP 220
           R + P
Sbjct: 426 RTLPP 430


>gi|217035158 zinc finger protein 780A isoform b [Homo sapiens]
          Length = 641

 Score = 27.7 bits (60), Expect = 9.5
 Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 7/72 (9%)

Query: 13  QRQGFHTVGS--RCKN--RTGAEHLWLTRHLRDPFVKAAK-VESYRCRSAFKLLEVNERH 67
           Q Q  HT      CK   +    H+  TRH +  F    K  E   C  AF LL +  RH
Sbjct: 182 QHQSIHTGEKPFECKECGKAFRLHIQFTRHQK--FHTGEKPFECNECGKAFSLLTLLNRH 239

Query: 68  QILRPGLRVLDC 79
           + +  G ++ +C
Sbjct: 240 KNIHTGEKLFEC 251


>gi|217035160 zinc finger protein 780A isoform b [Homo sapiens]
          Length = 641

 Score = 27.7 bits (60), Expect = 9.5
 Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 7/72 (9%)

Query: 13  QRQGFHTVGS--RCKN--RTGAEHLWLTRHLRDPFVKAAK-VESYRCRSAFKLLEVNERH 67
           Q Q  HT      CK   +    H+  TRH +  F    K  E   C  AF LL +  RH
Sbjct: 182 QHQSIHTGEKPFECKECGKAFRLHIQFTRHQK--FHTGEKPFECNECGKAFSLLTLLNRH 239

Query: 68  QILRPGLRVLDC 79
           + +  G ++ +C
Sbjct: 240 KNIHTGEKLFEC 251


>gi|217035156 zinc finger protein 780A isoform a [Homo sapiens]
          Length = 642

 Score = 27.7 bits (60), Expect = 9.5
 Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 7/72 (9%)

Query: 13  QRQGFHTVGS--RCKN--RTGAEHLWLTRHLRDPFVKAAK-VESYRCRSAFKLLEVNERH 67
           Q Q  HT      CK   +    H+  TRH +  F    K  E   C  AF LL +  RH
Sbjct: 183 QHQSIHTGEKPFECKECGKAFRLHIQFTRHQK--FHTGEKPFECNECGKAFSLLTLLNRH 240

Query: 68  QILRPGLRVLDC 79
           + +  G ++ +C
Sbjct: 241 KNIHTGEKLFEC 252


>gi|62865883 zinc finger protein 2 isoform b [Homo sapiens]
          Length = 383

 Score = 27.7 bits (60), Expect = 9.5
 Identities = 16/56 (28%), Positives = 26/56 (46%), Gaps = 1/56 (1%)

Query: 35  LTRHLRDPFVKAAKVESYRCRSAFKLLEVNERHQILRPGLRVLDCGAAPGAWSQVA 90
           LTRH R      +  E ++C  AF    +  RHQ++  G +  +C     A+  V+
Sbjct: 230 LTRHQRI-HTGESPYECHQCGKAFSQKSILTRHQLIHTGRKPYECNECGKAFYGVS 284


>gi|62865881 zinc finger protein 2 isoform a [Homo sapiens]
          Length = 425

 Score = 27.7 bits (60), Expect = 9.5
 Identities = 16/56 (28%), Positives = 26/56 (46%), Gaps = 1/56 (1%)

Query: 35  LTRHLRDPFVKAAKVESYRCRSAFKLLEVNERHQILRPGLRVLDCGAAPGAWSQVA 90
           LTRH R      +  E ++C  AF    +  RHQ++  G +  +C     A+  V+
Sbjct: 272 LTRHQRI-HTGESPYECHQCGKAFSQKSILTRHQLIHTGRKPYECNECGKAFYGVS 326


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,972,696
Number of Sequences: 37866
Number of extensions: 436913
Number of successful extensions: 1160
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1129
Number of HSP's gapped (non-prelim): 35
length of query: 246
length of database: 18,247,518
effective HSP length: 100
effective length of query: 146
effective length of database: 14,460,918
effective search space: 2111294028
effective search space used: 2111294028
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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