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Search of human proteins with 6912534
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6912534 BMP and activin membrane-bound inhibitor precursor
[Homo sapiens]
(260 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6912534 BMP and activin membrane-bound inhibitor precursor [H... 541 e-154
gi|161333833 activin A receptor, type IC isoform 1 [Homo sapiens] 36 0.029
gi|161333839 activin A receptor, type IC isoform 4 [Homo sapiens] 35 0.050
gi|161333837 activin A receptor, type IC isoform 3 [Homo sapiens] 35 0.050
gi|41349437 bone morphogenetic protein receptor, type IA precurs... 32 0.72
gi|227430289 sodium channel, nonvoltage-gated 1 alpha isoform 2 ... 31 1.2
gi|227430287 sodium channel, nonvoltage-gated 1 alpha isoform 3 ... 31 1.2
gi|4506815 sodium channel, nonvoltage-gated 1 alpha isoform 1 [H... 31 1.2
gi|157384998 low density lipoprotein receptor-related protein 4 ... 30 1.6
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 30 1.6
gi|4503365 dolichyl-phosphate mannosyltransferase 2 [Homo sapiens] 30 2.1
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 29 3.6
gi|208431840 lymphocyte antigen 6 complex, locus H isoform b [Ho... 29 4.7
gi|208431838 lymphocyte antigen 6 complex, locus H isoform a [Ho... 29 4.7
gi|194440697 lymphocyte antigen 6 complex, locus H isoform b [Ho... 29 4.7
gi|45387925 LY6/PLAUR domain containing 2 [Homo sapiens] 29 4.7
gi|157738645 plexin A4 isoform 1 [Homo sapiens] 28 6.1
gi|4507285 syntaxin 10 [Homo sapiens] 28 6.1
gi|161333835 activin A receptor, type IC isoform 2 [Homo sapiens] 28 8.0
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 28 8.0
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 28 8.0
>gi|6912534 BMP and activin membrane-bound inhibitor precursor [Homo
sapiens]
Length = 260
Score = 541 bits (1395), Expect = e-154
Identities = 260/260 (100%), Positives = 260/260 (100%)
Query: 1 MDRHSSYIFIWLQLELCAMAVLLTKGEIRCYCDAAHCVATGYMCKSELSACFSRLLDPQN 60
MDRHSSYIFIWLQLELCAMAVLLTKGEIRCYCDAAHCVATGYMCKSELSACFSRLLDPQN
Sbjct: 1 MDRHSSYIFIWLQLELCAMAVLLTKGEIRCYCDAAHCVATGYMCKSELSACFSRLLDPQN 60
Query: 61 SNSPLTHGCLDSLASTTDICQAKQARNHSGTTIPTLECCHEDMCNYRGLHDVLSPPRGEA 120
SNSPLTHGCLDSLASTTDICQAKQARNHSGTTIPTLECCHEDMCNYRGLHDVLSPPRGEA
Sbjct: 61 SNSPLTHGCLDSLASTTDICQAKQARNHSGTTIPTLECCHEDMCNYRGLHDVLSPPRGEA 120
Query: 121 SGQGNRYQHDGSRNLITKVQELTSSKELWFRAAVIAVPIAGGLILVLLIMLALRMLRSEN 180
SGQGNRYQHDGSRNLITKVQELTSSKELWFRAAVIAVPIAGGLILVLLIMLALRMLRSEN
Sbjct: 121 SGQGNRYQHDGSRNLITKVQELTSSKELWFRAAVIAVPIAGGLILVLLIMLALRMLRSEN 180
Query: 181 KRLQDQRQQMLSRLHYSFHGHHSKKGQVAKLDLECMVPVSGHENCCLTCDKMRQADLSND 240
KRLQDQRQQMLSRLHYSFHGHHSKKGQVAKLDLECMVPVSGHENCCLTCDKMRQADLSND
Sbjct: 181 KRLQDQRQQMLSRLHYSFHGHHSKKGQVAKLDLECMVPVSGHENCCLTCDKMRQADLSND 240
Query: 241 KILSLVHWGMYSGHGKLEFV 260
KILSLVHWGMYSGHGKLEFV
Sbjct: 241 KILSLVHWGMYSGHGKLEFV 260
>gi|161333833 activin A receptor, type IC isoform 1 [Homo sapiens]
Length = 493
Score = 36.2 bits (82), Expect = 0.029
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 13/110 (11%)
Query: 14 LELCAMAVLLTKGEIRCYCDAAHCVATGYMCKSELSACFSRLLDPQNSNSPLTHGCLDSL 73
L L A A L+ G ++C C C ++ + C++E AC++ ++ LT+G +
Sbjct: 13 LLLLAAAAELSPG-LKCVC--LLCDSSNFTCQTE-GACWASVM--------LTNGKEQVI 60
Query: 74 ASTTDICQAK-QARNHSGTTIPTLECCHEDMCNYRGLHDVLSPPRGEASG 122
S + + Q HS + ECC D CN LH + P G
Sbjct: 61 KSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLHLPTASPNAPKLG 110
>gi|161333839 activin A receptor, type IC isoform 4 [Homo sapiens]
Length = 336
Score = 35.4 bits (80), Expect = 0.050
Identities = 28/98 (28%), Positives = 45/98 (45%), Gaps = 13/98 (13%)
Query: 14 LELCAMAVLLTKGEIRCYCDAAHCVATGYMCKSELSACFSRLLDPQNSNSPLTHGCLDSL 73
L L A A L+ G ++C C C ++ + C++E AC++ ++ LT+G +
Sbjct: 13 LLLLAAAAELSPG-LKCVC--LLCDSSNFTCQTE-GACWASVM--------LTNGKEQVI 60
Query: 74 ASTTDICQAK-QARNHSGTTIPTLECCHEDMCNYRGLH 110
S + + Q HS + ECC D CN LH
Sbjct: 61 KSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLH 98
>gi|161333837 activin A receptor, type IC isoform 3 [Homo sapiens]
Length = 413
Score = 35.4 bits (80), Expect = 0.050
Identities = 28/98 (28%), Positives = 45/98 (45%), Gaps = 13/98 (13%)
Query: 14 LELCAMAVLLTKGEIRCYCDAAHCVATGYMCKSELSACFSRLLDPQNSNSPLTHGCLDSL 73
L L A A L+ G ++C C C ++ + C++E AC++ ++ LT+G +
Sbjct: 13 LLLLAAAAELSPG-LKCVC--LLCDSSNFTCQTE-GACWASVM--------LTNGKEQVI 60
Query: 74 ASTTDICQAK-QARNHSGTTIPTLECCHEDMCNYRGLH 110
S + + Q HS + ECC D CN LH
Sbjct: 61 KSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLH 98
>gi|41349437 bone morphogenetic protein receptor, type IA precursor
[Homo sapiens]
Length = 532
Score = 31.6 bits (70), Expect = 0.72
Identities = 20/80 (25%), Positives = 35/80 (43%), Gaps = 9/80 (11%)
Query: 28 IRCYCDAAHCV--ATGYMCKSELSACFSRLLDPQNSNSPLTHGCLDSLASTTDICQAKQA 85
++CYC + HC A C + CF+ + + + L GC+ S + +A
Sbjct: 59 LKCYC-SGHCPDDAINNTCITN-GHCFAIIEEDDQGETTLASGCMKYEGSDFQCKDSPKA 116
Query: 86 RNHSGTTIPTLECCHEDMCN 105
+ T+ECC ++CN
Sbjct: 117 QLRR-----TIECCRTNLCN 131
>gi|227430289 sodium channel, nonvoltage-gated 1 alpha isoform 2
[Homo sapiens]
Length = 728
Score = 30.8 bits (68), Expect = 1.2
Identities = 16/51 (31%), Positives = 28/51 (54%)
Query: 132 SRNLITKVQELTSSKELWFRAAVIAVPIAGGLILVLLIMLALRMLRSENKR 182
S ++T + L S LWF ++V++V L+ LL+++ L +LR R
Sbjct: 600 SVTMVTLLSNLGSQWSLWFGSSVLSVVEMAELVFDLLVIMFLMLLRRFRSR 650
>gi|227430287 sodium channel, nonvoltage-gated 1 alpha isoform 3
[Homo sapiens]
Length = 692
Score = 30.8 bits (68), Expect = 1.2
Identities = 16/51 (31%), Positives = 28/51 (54%)
Query: 132 SRNLITKVQELTSSKELWFRAAVIAVPIAGGLILVLLIMLALRMLRSENKR 182
S ++T + L S LWF ++V++V L+ LL+++ L +LR R
Sbjct: 564 SVTMVTLLSNLGSQWSLWFGSSVLSVVEMAELVFDLLVIMFLMLLRRFRSR 614
>gi|4506815 sodium channel, nonvoltage-gated 1 alpha isoform 1 [Homo
sapiens]
Length = 669
Score = 30.8 bits (68), Expect = 1.2
Identities = 16/51 (31%), Positives = 28/51 (54%)
Query: 132 SRNLITKVQELTSSKELWFRAAVIAVPIAGGLILVLLIMLALRMLRSENKR 182
S ++T + L S LWF ++V++V L+ LL+++ L +LR R
Sbjct: 541 SVTMVTLLSNLGSQWSLWFGSSVLSVVEMAELVFDLLVIMFLMLLRRFRSR 591
>gi|157384998 low density lipoprotein receptor-related protein 4
[Homo sapiens]
Length = 1905
Score = 30.4 bits (67), Expect = 1.6
Identities = 21/74 (28%), Positives = 30/74 (40%), Gaps = 17/74 (22%)
Query: 32 CDAAHCVATGYMCKSELSACFSRLLDPQNSNSPLTHGCLDSLASTTDICQAKQARNHSGT 91
CD+ C+ G+ C + D Q+ D TT +C A+Q R HSG
Sbjct: 238 CDSGLCINAGWRCDGDADC------DDQS----------DERNCTTSMCTAEQFRCHSGR 281
Query: 92 TIP-TLECCHEDMC 104
+ + C ED C
Sbjct: 282 CVRLSWRCDGEDDC 295
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 30.4 bits (67), Expect = 1.6
Identities = 23/95 (24%), Positives = 36/95 (37%), Gaps = 10/95 (10%)
Query: 14 LELCAMAVLLTKGEIRCYCDAAHCVATGYMCKSELSACFSRLLDPQNS----NSPLTHGC 69
L CA L T+G +C C A GY ++ C+ ++ NS N +HGC
Sbjct: 293 LAQCAHGCLNTQGSFKCVCHA------GYELGADGRQCYRIEMEIVNSCEANNGGCSHGC 346
Query: 70 LDSLASTTDICQAKQARNHSGTTIPTLECCHEDMC 104
+ A C + T ++ C + C
Sbjct: 347 SHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPC 381
>gi|4503365 dolichyl-phosphate mannosyltransferase 2 [Homo sapiens]
Length = 84
Score = 30.0 bits (66), Expect = 2.1
Identities = 13/38 (34%), Positives = 24/38 (63%)
Query: 151 RAAVIAVPIAGGLILVLLIMLALRMLRSENKRLQDQRQ 188
RA +A+P+A GL+L+L + L + + + KR+ + Q
Sbjct: 47 RAYAVAIPLAAGLLLLLFVGLFISYVMLKTKRVTKKAQ 84
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 29.3 bits (64), Expect = 3.6
Identities = 12/32 (37%), Positives = 23/32 (71%)
Query: 183 LQDQRQQMLSRLHYSFHGHHSKKGQVAKLDLE 214
LQ + +++LS+L + H +HS + ++AKL+ E
Sbjct: 2282 LQGENKELLSQLEETRHLYHSSQNELAKLESE 2313
>gi|208431840 lymphocyte antigen 6 complex, locus H isoform b [Homo
sapiens]
Length = 161
Score = 28.9 bits (63), Expect = 4.7
Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 11/80 (13%)
Query: 33 DAAHCVATGYMCKSELSACFS-RLLDPQNSNSPLTHGCLDSLASTTDICQAKQARNH--- 88
+++HC T C+ + C S R+ DP +S H AS+ D + ++
Sbjct: 57 NSSHC--TPKQCQPSDTVCASVRITDPSSSRKD--HSVNKMCASSCDFVKRHFFSDYLMG 112
Query: 89 ---SGTTIPTLECCHEDMCN 105
SG ++CC +D+CN
Sbjct: 113 FINSGILKVDVDCCEKDLCN 132
>gi|208431838 lymphocyte antigen 6 complex, locus H isoform a [Homo
sapiens]
Length = 140
Score = 28.9 bits (63), Expect = 4.7
Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 11/80 (13%)
Query: 33 DAAHCVATGYMCKSELSACFS-RLLDPQNSNSPLTHGCLDSLASTTDICQAKQARNH--- 88
+++HC T C+ + C S R+ DP +S H AS+ D + ++
Sbjct: 36 NSSHC--TPKQCQPSDTVCASVRITDPSSSRKD--HSVNKMCASSCDFVKRHFFSDYLMG 91
Query: 89 ---SGTTIPTLECCHEDMCN 105
SG ++CC +D+CN
Sbjct: 92 FINSGILKVDVDCCEKDLCN 111
>gi|194440697 lymphocyte antigen 6 complex, locus H isoform b [Homo
sapiens]
Length = 161
Score = 28.9 bits (63), Expect = 4.7
Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 11/80 (13%)
Query: 33 DAAHCVATGYMCKSELSACFS-RLLDPQNSNSPLTHGCLDSLASTTDICQAKQARNH--- 88
+++HC T C+ + C S R+ DP +S H AS+ D + ++
Sbjct: 57 NSSHC--TPKQCQPSDTVCASVRITDPSSSRKD--HSVNKMCASSCDFVKRHFFSDYLMG 112
Query: 89 ---SGTTIPTLECCHEDMCN 105
SG ++CC +D+CN
Sbjct: 113 FINSGILKVDVDCCEKDLCN 132
>gi|45387925 LY6/PLAUR domain containing 2 [Homo sapiens]
Length = 125
Score = 28.9 bits (63), Expect = 4.7
Identities = 22/75 (29%), Positives = 36/75 (48%), Gaps = 13/75 (17%)
Query: 35 AHCVATGYMCKSELSACFSR-LLDPQNSNSPLTHGCLDSLASTTDICQAKQARNHSGTTI 93
A C MCK+ L +SR ++ P +S +T C S +D+ + G T+
Sbjct: 41 ATCTTNETMCKTTL---YSREIVYPFQGDSTVTKSCA-SKCKPSDV-------DGIGQTL 89
Query: 94 PTLECCHEDMCNYRG 108
P + CC+ ++CN G
Sbjct: 90 P-VSCCNTELCNVDG 103
>gi|157738645 plexin A4 isoform 1 [Homo sapiens]
Length = 1894
Score = 28.5 bits (62), Expect = 6.1
Identities = 13/48 (27%), Positives = 27/48 (56%), Gaps = 6/48 (12%)
Query: 153 AVIAVPIAGGLILVLLIMLALRMLRSEN------KRLQDQRQQMLSRL 194
A++++ +AGGL+++ ++ + + R KRLQ Q + SR+
Sbjct: 1238 AIVSIAVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRV 1285
>gi|4507285 syntaxin 10 [Homo sapiens]
Length = 249
Score = 28.5 bits (62), Expect = 6.1
Identities = 15/44 (34%), Positives = 24/44 (54%), Gaps = 4/44 (9%)
Query: 130 DGSRNLITKVQELTSSKELWFRAAVIAVPIAGGLILVLLIMLAL 173
DG + KV +TS + W AV + G L+LVL+++ +L
Sbjct: 210 DGVLRKLAKVSHMTSDRRQWCAIAV----LVGVLLLVLILLFSL 249
>gi|161333835 activin A receptor, type IC isoform 2 [Homo sapiens]
Length = 443
Score = 28.1 bits (61), Expect = 8.0
Identities = 12/35 (34%), Positives = 14/35 (40%)
Query: 88 HSGTTIPTLECCHEDMCNYRGLHDVLSPPRGEASG 122
HS + ECC D CN LH + P G
Sbjct: 26 HSSNNVTKTECCFTDFCNNITLHLPTASPNAPKLG 60
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1
precursor [Homo sapiens]
Length = 1907
Score = 28.1 bits (61), Expect = 8.0
Identities = 17/79 (21%), Positives = 36/79 (45%), Gaps = 6/79 (7%)
Query: 136 ITKVQELTSSKELWFRAAVIAVPIAGGLILVLLIMLALRMLRSENKRLQDQRQQMLSRLH 195
+T Q+ + LW V+AV IL++LI++A+ + + + + + L
Sbjct: 1250 VTPAQQQEEPEMLWVTGPVLAV------ILIILIVIAILLFKRKRTHSPSSKDEQSIGLK 1303
Query: 196 YSFHGHHSKKGQVAKLDLE 214
S H S ++ +L+ +
Sbjct: 1304 DSLLAHSSDPVEMRRLNYQ 1322
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
precursor [Homo sapiens]
Length = 1898
Score = 28.1 bits (61), Expect = 8.0
Identities = 17/79 (21%), Positives = 36/79 (45%), Gaps = 6/79 (7%)
Query: 136 ITKVQELTSSKELWFRAAVIAVPIAGGLILVLLIMLALRMLRSENKRLQDQRQQMLSRLH 195
+T Q+ + LW V+AV IL++LI++A+ + + + + + L
Sbjct: 1241 VTPAQQQEEPEMLWVTGPVLAV------ILIILIVIAILLFKRKRTHSPSSKDEQSIGLK 1294
Query: 196 YSFHGHHSKKGQVAKLDLE 214
S H S ++ +L+ +
Sbjct: 1295 DSLLAHSSDPVEMRRLNYQ 1313
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.135 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,898,776
Number of Sequences: 37866
Number of extensions: 413422
Number of successful extensions: 1469
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1459
Number of HSP's gapped (non-prelim): 22
length of query: 260
length of database: 18,247,518
effective HSP length: 100
effective length of query: 160
effective length of database: 14,460,918
effective search space: 2313746880
effective search space used: 2313746880
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.