Guide to the Human Genome
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Search of human proteins with 6912442

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|6912442 potassium voltage-gated channel, Isk-related family,
member 1-like [Homo sapiens]
         (142 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|6912442 potassium voltage-gated channel, Isk-related family, ...   283   4e-77
gi|4885443 potassium voltage-gated channel, Isk-related family, ...    46   9e-06
gi|189095241 potassium voltage-gated channel, Isk-related family...    33   0.10 
gi|189095239 potassium voltage-gated channel, Isk-related family...    33   0.10 
gi|189095237 potassium voltage-gated channel, Isk-related family...    33   0.10 
gi|60218915 potassium voltage-gated channel, Isk-related family,...    33   0.10 
gi|154448884 potassium voltage-gated channel, Isk-related family...    31   0.30 
gi|224809302 xeroderma pigmentosum, complementation group C isof...    30   0.88 
gi|224809295 xeroderma pigmentosum, complementation group C isof...    30   0.88 
gi|5453613 CD7 antigen precursor [Homo sapiens]                        28   2.0  
gi|24371268 nucleosome assembly protein 1-like 5 [Homo sapiens]        28   2.0  
gi|239747812 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]        28   3.3  
gi|239753271 PREDICTED: similar to ankyrin repeat domain 36 [Hom...    27   4.4  
gi|197333692 leucine rich repeat containing 8 family, member B [...    27   4.4  
gi|21245134 leucine rich repeat containing 8 family, member B [H...    27   4.4  
gi|171543850 RUN domain containing 1 [Homo sapiens]                    27   4.4  
gi|20127580 BTB (POZ) domain containing 2 [Homo sapiens]               27   5.7  
gi|28416937 purinergic receptor P2X5 isoform C [Homo sapiens]          27   5.7  
gi|28416933 purinergic receptor P2X5 isoform A [Homo sapiens]          27   5.7  
gi|38569457 solute carrier family 12, member 8 [Homo sapiens]          27   5.7  
gi|45593144 gastrulation brain homeo box 2 [Homo sapiens]              27   5.7  
gi|239755296 PREDICTED: similar to hCG1644292 [Homo sapiens]           27   7.4  
gi|239749791 PREDICTED: similar to hCG1644292 [Homo sapiens]           27   7.4  
gi|27369497 carbohydrate (N-acetylglucosamine-6-O) sulfotransfer...    27   7.4  
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              27   7.4  
gi|65786661 BTB (POZ) domain containing 11 isoform a [Homo sapiens]    27   7.4  
gi|24497519 mannosidase, alpha, class 1A, member 1 [Homo sapiens]      26   9.7  

>gi|6912442 potassium voltage-gated channel, Isk-related family,
           member 1-like [Homo sapiens]
          Length = 142

 Score =  283 bits (723), Expect = 4e-77
 Identities = 142/142 (100%), Positives = 142/142 (100%)

Query: 1   MNCSESQRLRTLLSRLLLELHHRGNASGLGAGPRPSMGMGVVPDPFVGREVTSAKGDDAY 60
           MNCSESQRLRTLLSRLLLELHHRGNASGLGAGPRPSMGMGVVPDPFVGREVTSAKGDDAY
Sbjct: 1   MNCSESQRLRTLLSRLLLELHHRGNASGLGAGPRPSMGMGVVPDPFVGREVTSAKGDDAY 60

Query: 61  LYILLIMIFYACLAGGLILAYTRSRKLVEAKDEPSQACAEHEWAPGGALTADAEAAAGSQ 120
           LYILLIMIFYACLAGGLILAYTRSRKLVEAKDEPSQACAEHEWAPGGALTADAEAAAGSQ
Sbjct: 61  LYILLIMIFYACLAGGLILAYTRSRKLVEAKDEPSQACAEHEWAPGGALTADAEAAAGSQ 120

Query: 121 AEGRRQLASEGLPALAQGAERV 142
           AEGRRQLASEGLPALAQGAERV
Sbjct: 121 AEGRRQLASEGLPALAQGAERV 142


>gi|4885443 potassium voltage-gated channel, Isk-related family,
          member 3 [Homo sapiens]
          Length = 103

 Score = 46.2 bits (108), Expect = 9e-06
 Identities = 23/59 (38%), Positives = 32/59 (54%)

Query: 34 RPSMGMGVVPDPFVGREVTSAKGDDAYLYILLIMIFYACLAGGLILAYTRSRKLVEAKD 92
          RP  G+G        R     + D++Y+YIL +M  +A   G LIL YTRSRK+ +  D
Sbjct: 32 RPGPGLGPDNQTEERRASLPGRDDNSYMYILFVMFLFAVTVGSLILGYTRSRKVDKRSD 90


>gi|189095241 potassium voltage-gated channel, Isk-related family,
          member 1 [Homo sapiens]
          Length = 129

 Score = 32.7 bits (73), Expect = 0.10
 Identities = 15/44 (34%), Positives = 26/44 (59%)

Query: 49 REVTSAKGDDAYLYILLIMIFYACLAGGLILAYTRSRKLVEAKD 92
          R   S+ G    LY+L+++ F+     G++L+Y RS+KL  + D
Sbjct: 33 RSPRSSDGKLEALYVLMVLGFFGFFTLGIMLSYIRSKKLEHSND 76


>gi|189095239 potassium voltage-gated channel, Isk-related family,
          member 1 [Homo sapiens]
          Length = 129

 Score = 32.7 bits (73), Expect = 0.10
 Identities = 15/44 (34%), Positives = 26/44 (59%)

Query: 49 REVTSAKGDDAYLYILLIMIFYACLAGGLILAYTRSRKLVEAKD 92
          R   S+ G    LY+L+++ F+     G++L+Y RS+KL  + D
Sbjct: 33 RSPRSSDGKLEALYVLMVLGFFGFFTLGIMLSYIRSKKLEHSND 76


>gi|189095237 potassium voltage-gated channel, Isk-related family,
          member 1 [Homo sapiens]
          Length = 129

 Score = 32.7 bits (73), Expect = 0.10
 Identities = 15/44 (34%), Positives = 26/44 (59%)

Query: 49 REVTSAKGDDAYLYILLIMIFYACLAGGLILAYTRSRKLVEAKD 92
          R   S+ G    LY+L+++ F+     G++L+Y RS+KL  + D
Sbjct: 33 RSPRSSDGKLEALYVLMVLGFFGFFTLGIMLSYIRSKKLEHSND 76


>gi|60218915 potassium voltage-gated channel, Isk-related family,
          member 1 [Homo sapiens]
          Length = 129

 Score = 32.7 bits (73), Expect = 0.10
 Identities = 15/44 (34%), Positives = 26/44 (59%)

Query: 49 REVTSAKGDDAYLYILLIMIFYACLAGGLILAYTRSRKLVEAKD 92
          R   S+ G    LY+L+++ F+     G++L+Y RS+KL  + D
Sbjct: 33 RSPRSSDGKLEALYVLMVLGFFGFFTLGIMLSYIRSKKLEHSND 76


>gi|154448884 potassium voltage-gated channel, Isk-related family,
          member 4 [Homo sapiens]
          Length = 170

 Score = 31.2 bits (69), Expect = 0.30
 Identities = 15/50 (30%), Positives = 24/50 (48%), Gaps = 1/50 (2%)

Query: 38 GMGVVPDPFVGREVTSAKGD-DAYLYILLIMIFYACLAGGLILAYTRSRK 86
          G      P   R      G+ + Y YIL++M FY     G++L Y +S++
Sbjct: 13 GTAASSSPLESRAAGGGSGNGNEYFYILVVMSFYGIFLIGIMLGYMKSKR 62


>gi|224809302 xeroderma pigmentosum, complementation group C isoform
           2 [Homo sapiens]
          Length = 903

 Score = 29.6 bits (65), Expect = 0.88
 Identities = 22/57 (38%), Positives = 29/57 (50%), Gaps = 5/57 (8%)

Query: 73  LAGGLILAYTRSRKLVEAKDEPSQACAEHEWAPGGALTADAEAAAGSQAEGRRQLAS 129
           LA GL++     R+        S+A A H  A GG L++D E    SQAE  R LA+
Sbjct: 814 LAKGLLIRERLKRRY----GPKSEAAAPHTDA-GGGLSSDEEEGTSSQAEAARILAA 865


>gi|224809295 xeroderma pigmentosum, complementation group C isoform
           1 [Homo sapiens]
          Length = 940

 Score = 29.6 bits (65), Expect = 0.88
 Identities = 22/57 (38%), Positives = 29/57 (50%), Gaps = 5/57 (8%)

Query: 73  LAGGLILAYTRSRKLVEAKDEPSQACAEHEWAPGGALTADAEAAAGSQAEGRRQLAS 129
           LA GL++     R+        S+A A H  A GG L++D E    SQAE  R LA+
Sbjct: 851 LAKGLLIRERLKRRY----GPKSEAAAPHTDA-GGGLSSDEEEGTSSQAEAARILAA 902


>gi|5453613 CD7 antigen precursor [Homo sapiens]
          Length = 240

 Score = 28.5 bits (62), Expect = 2.0
 Identities = 21/72 (29%), Positives = 32/72 (44%), Gaps = 3/72 (4%)

Query: 33  PRPSMGMGVVPDPFVGREVTSAKGDDAYLYILLIMIFYACLAGGL--ILAYTRSRKLVEA 90
           P P  G   +PDP     +       A    L ++ F   L  G+  +LA T+ +KL   
Sbjct: 153 PAPPTG-SALPDPQTASALPDPPAASALPAALAVISFLLGLGLGVACVLARTQIKKLCSW 211

Query: 91  KDEPSQACAEHE 102
           +D+ S AC  +E
Sbjct: 212 RDKNSAACVVYE 223


>gi|24371268 nucleosome assembly protein 1-like 5 [Homo sapiens]
          Length = 182

 Score = 28.5 bits (62), Expect = 2.0
 Identities = 18/44 (40%), Positives = 21/44 (47%), Gaps = 6/44 (13%)

Query: 93  EPSQACA------EHEWAPGGALTADAEAAAGSQAEGRRQLASE 130
           EPSQA A      E   A GGA   D ++AAG       Q+A E
Sbjct: 11  EPSQAAAAAEAAAEEVMAEGGAQGGDCDSAAGDPDSAAGQMAEE 54


>gi|239747812 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
          Length = 753

 Score = 27.7 bits (60), Expect = 3.3
 Identities = 17/46 (36%), Positives = 21/46 (45%), Gaps = 7/46 (15%)

Query: 94  PSQACAEHEWAPGGALTADAEAAAGSQAEGRRQLASEGLPALAQGA 139
           P QACA     PG +L A ++A  G       + A  GLP   Q A
Sbjct: 111 PDQACASSRADPGASLAAASQAVCG-------RSAGHGLPPGVQEA 149


>gi|239753271 PREDICTED: similar to ankyrin repeat domain 36 [Homo
           sapiens]
          Length = 501

 Score = 27.3 bits (59), Expect = 4.4
 Identities = 12/28 (42%), Positives = 15/28 (53%)

Query: 94  PSQACAEHEWAPGGALTADAEAAAGSQA 121
           P QACA     PG +L A ++A  G  A
Sbjct: 301 PDQACASSRADPGASLAAASQAVCGRSA 328


>gi|197333692 leucine rich repeat containing 8 family, member B
          [Homo sapiens]
          Length = 803

 Score = 27.3 bits (59), Expect = 4.4
 Identities = 17/43 (39%), Positives = 21/43 (48%)

Query: 57 DDAYLYILLIMIFYACLAGGLILAYTRSRKLVEAKDEPSQACA 99
          D  + YI LIM+  A LAG L L  +R    +  K E    CA
Sbjct: 25 DVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCA 67


>gi|21245134 leucine rich repeat containing 8 family, member B
          [Homo sapiens]
          Length = 803

 Score = 27.3 bits (59), Expect = 4.4
 Identities = 17/43 (39%), Positives = 21/43 (48%)

Query: 57 DDAYLYILLIMIFYACLAGGLILAYTRSRKLVEAKDEPSQACA 99
          D  + YI LIM+  A LAG L L  +R    +  K E    CA
Sbjct: 25 DVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNHCA 67


>gi|171543850 RUN domain containing 1 [Homo sapiens]
          Length = 613

 Score = 27.3 bits (59), Expect = 4.4
 Identities = 19/51 (37%), Positives = 24/51 (47%), Gaps = 5/51 (9%)

Query: 89  EAKDEPSQACAEHEWAPGGALTADAEAAAGSQAEGRRQLASEGLPALAQGA 139
           E ++EP   C    WAP GA+   AEA  G+ A      A E  P  A G+
Sbjct: 26  EEEEEPLPPCEAVRWAPVGAV---AEARPGATAFLEEATAEE--PGAAPGS 71


>gi|20127580 BTB (POZ) domain containing 2 [Homo sapiens]
          Length = 525

 Score = 26.9 bits (58), Expect = 5.7
 Identities = 19/40 (47%), Positives = 20/40 (50%), Gaps = 2/40 (5%)

Query: 104 APGGALTADAEAAAGSQAEGRRQLA--SEGLPALAQGAER 141
           APG A  A A AAA + A G    A    G  A A GAER
Sbjct: 37  APGNAAAAAAAAAAAAAAPGPTPPAPPGPGTDAQAAGAER 76


>gi|28416937 purinergic receptor P2X5 isoform C [Homo sapiens]
          Length = 178

 Score = 26.9 bits (58), Expect = 5.7
 Identities = 11/32 (34%), Positives = 18/32 (56%)

Query: 87  LVEAKDEPSQACAEHEWAPGGALTADAEAAAG 118
           L+   ++    CAE+E  P GA + D++  AG
Sbjct: 107 LIVTPNQRQNVCAENEGIPDGACSKDSDCHAG 138


>gi|28416933 purinergic receptor P2X5 isoform A [Homo sapiens]
          Length = 422

 Score = 26.9 bits (58), Expect = 5.7
 Identities = 11/32 (34%), Positives = 18/32 (56%)

Query: 87  LVEAKDEPSQACAEHEWAPGGALTADAEAAAG 118
           L+   ++    CAE+E  P GA + D++  AG
Sbjct: 107 LIVTPNQRQNVCAENEGIPDGACSKDSDCHAG 138


>gi|38569457 solute carrier family 12, member 8 [Homo sapiens]
          Length = 714

 Score = 26.9 bits (58), Expect = 5.7
 Identities = 17/53 (32%), Positives = 26/53 (49%), Gaps = 5/53 (9%)

Query: 27  SGLGAGPRPSMGMGVVPDPFVGREVTSAKGDDAYLYILLIMIFYACLAGGLIL 79
           SG+G G R S+G G V        ++S  G      I L+ +F  C+AG + +
Sbjct: 91  SGIGVGERSSIGSGGVYS-----MISSVLGGQTGGTIGLLYVFGQCVAGAMYI 138


>gi|45593144 gastrulation brain homeo box 2 [Homo sapiens]
          Length = 348

 Score = 26.9 bits (58), Expect = 5.7
 Identities = 25/81 (30%), Positives = 33/81 (40%), Gaps = 7/81 (8%)

Query: 69  FYACLAGGLILAYTRSRKL---VEAKDEPSQACAEHEWAP----GGALTADAEAAAGSQA 121
           F + LA G+ L  T    L     A  +  +A A  ++AP    GG     AEA      
Sbjct: 90  FCSSLAQGMALTSTLMATLPGGFSASPQHQEAAAARKFAPQPLPGGGNFDKAEALQADAE 149

Query: 122 EGRRQLASEGLPALAQGAERV 142
           +G+  LA EG       AE V
Sbjct: 150 DGKGFLAKEGSLLAFSAAETV 170


>gi|239755296 PREDICTED: similar to hCG1644292 [Homo sapiens]
          Length = 671

 Score = 26.6 bits (57), Expect = 7.4
 Identities = 14/35 (40%), Positives = 17/35 (48%)

Query: 105 PGGALTADAEAAAGSQAEGRRQLASEGLPALAQGA 139
           PGG L  +A AAA  Q   +R+     L  LA  A
Sbjct: 470 PGGLLAREAHAAAPVQTRSQRRRRGPSLARLADSA 504


>gi|239749791 PREDICTED: similar to hCG1644292 [Homo sapiens]
          Length = 671

 Score = 26.6 bits (57), Expect = 7.4
 Identities = 14/35 (40%), Positives = 17/35 (48%)

Query: 105 PGGALTADAEAAAGSQAEGRRQLASEGLPALAQGA 139
           PGG L  +A AAA  Q   +R+     L  LA  A
Sbjct: 470 PGGLLAREAHAAAPVQTRSQRRRRGPSLARLADSA 504


>gi|27369497 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase
           2 [Homo sapiens]
          Length = 530

 Score = 26.6 bits (57), Expect = 7.4
 Identities = 18/49 (36%), Positives = 23/49 (46%), Gaps = 1/49 (2%)

Query: 14  SRLLLELHHRGNASGLGAGPRPSMGM-GVVPDPFVGREVTSAKGDDAYL 61
           +RL L   +R  A+ +GA P  + GM GV   P  G   T   GD   L
Sbjct: 118 ARLDLRTPYRPPAAAVGAAPAAAAGMAGVAAPPGNGTRGTGGVGDKRQL 166


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 26.6 bits (57), Expect = 7.4
 Identities = 15/46 (32%), Positives = 23/46 (50%)

Query: 93   EPSQACAEHEWAPGGALTADAEAAAGSQAEGRRQLASEGLPALAQG 138
            E  +A  E +  P G  T +AE  A  ++EG  Q   +G P ++ G
Sbjct: 2213 EAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLG 2258


>gi|65786661 BTB (POZ) domain containing 11 isoform a [Homo sapiens]
          Length = 1104

 Score = 26.6 bits (57), Expect = 7.4
 Identities = 11/20 (55%), Positives = 12/20 (60%)

Query: 24  GNASGLGAGPRPSMGMGVVP 43
           G  SG G+GP PS G G  P
Sbjct: 263 GPGSGSGSGPGPSSGPGAAP 282


>gi|24497519 mannosidase, alpha, class 1A, member 1 [Homo sapiens]
          Length = 653

 Score = 26.2 bits (56), Expect = 9.7
 Identities = 23/81 (28%), Positives = 31/81 (38%), Gaps = 12/81 (14%)

Query: 63  ILLIMIFYACLAGGLILAYTRSRKLVEA----KDEPSQACAEHEWAPGGALTADAEAAAG 118
           +LL+   +  L  G I     S KL+           Q  A+H+  PG        A A 
Sbjct: 44  LLLVFSAFITLCFGAIFFLPDSSKLLSGVLFHSSPALQPAADHKPGPG--------ARAE 95

Query: 119 SQAEGRRQLASEGLPALAQGA 139
             AEGR +   EG P   + A
Sbjct: 96  DAAEGRARRREEGAPGDPEAA 116


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,684,680
Number of Sequences: 37866
Number of extensions: 251799
Number of successful extensions: 955
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 929
Number of HSP's gapped (non-prelim): 33
length of query: 142
length of database: 18,247,518
effective HSP length: 92
effective length of query: 50
effective length of database: 14,763,846
effective search space: 738192300
effective search space used: 738192300
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 56 (26.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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