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Search of human proteins with 6912236
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6912236 angiopoietin-like 2 precursor [Homo sapiens]
(493 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6912236 angiopoietin-like 2 precursor [Homo sapiens] 1039 0.0
gi|4757752 angiopoietin-like 1 precursor [Homo sapiens] 580 e-166
gi|29893555 angiopoietin-like 6 [Homo sapiens] 418 e-117
gi|223029463 fibrinogen C domain containing 1 [Homo sapiens] 211 2e-54
gi|223029461 fibrinogen C domain containing 1 [Homo sapiens] 211 2e-54
gi|20532340 angiopoietin 1 [Homo sapiens] 207 2e-53
gi|4557315 angiopoietin 2 isoform a precursor [Homo sapiens] 207 2e-53
gi|169646749 angiopoietin 2 isoform b precursor [Homo sapiens] 204 1e-52
gi|42544202 fibrinogen-like 1 precursor [Homo sapiens] 204 2e-52
gi|42544200 fibrinogen-like 1 precursor [Homo sapiens] 204 2e-52
gi|42544198 fibrinogen-like 1 precursor [Homo sapiens] 204 2e-52
gi|42544189 fibrinogen-like 1 precursor [Homo sapiens] 204 2e-52
gi|169646754 angiopoietin 2 isoform c precursor [Homo sapiens] 201 2e-51
gi|7705276 angiopoietin 4 [Homo sapiens] 200 2e-51
gi|4503689 fibrinogen, alpha polypeptide isoform alpha-E preprop... 197 2e-50
gi|10863949 angiopoietin-like 7 [Homo sapiens] 196 5e-50
gi|27754778 ficolin 3 isoform 2 precursor [Homo sapiens] 193 3e-49
gi|27754776 ficolin 3 isoform 1 precursor [Homo sapiens] 193 3e-49
gi|8051586 ficolin 2 isoform b precursor [Homo sapiens] 192 4e-49
gi|61744445 ficolin 2 isoform a precursor [Homo sapiens] 192 4e-49
gi|157384973 tenascin R [Homo sapiens] 191 1e-48
gi|70906435 fibrinogen, beta chain preproprotein [Homo sapiens] 190 2e-48
gi|8051584 ficolin 1 precursor [Homo sapiens] 188 8e-48
gi|23111005 microfibrillar-associated protein 4 [Homo sapiens] 188 8e-48
gi|70906439 fibrinogen, gamma chain isoform gamma-B precursor [H... 182 5e-46
gi|70906437 fibrinogen, gamma chain isoform gamma-A precursor [H... 182 5e-46
gi|5730075 fibrinogen-like 2 precursor [Homo sapiens] 173 4e-43
gi|20665034 tenascin XB isoform 2 [Homo sapiens] 172 5e-43
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 172 5e-43
gi|62988324 tenascin N [Homo sapiens] 165 8e-41
>gi|6912236 angiopoietin-like 2 precursor [Homo sapiens]
Length = 493
Score = 1039 bits (2686), Expect = 0.0
Identities = 493/493 (100%), Positives = 493/493 (100%)
Query: 1 MRPLCVTCWWLGLLAAMGAVAGQEDGFEGTEEGSPREFIYLNRYKRAGESQDKCTYTFIV 60
MRPLCVTCWWLGLLAAMGAVAGQEDGFEGTEEGSPREFIYLNRYKRAGESQDKCTYTFIV
Sbjct: 1 MRPLCVTCWWLGLLAAMGAVAGQEDGFEGTEEGSPREFIYLNRYKRAGESQDKCTYTFIV 60
Query: 61 PQQRVTGAICVNSKEPEVLLENRVHKQELELLNNELLKQKRQIETLQQLVEVDGGIVSEV 120
PQQRVTGAICVNSKEPEVLLENRVHKQELELLNNELLKQKRQIETLQQLVEVDGGIVSEV
Sbjct: 61 PQQRVTGAICVNSKEPEVLLENRVHKQELELLNNELLKQKRQIETLQQLVEVDGGIVSEV 120
Query: 121 KLLRKESRNMNSRVTQLYMQLLHEIIRKRDNALELSQLENRILNQTADMLQLASKYKDLE 180
KLLRKESRNMNSRVTQLYMQLLHEIIRKRDNALELSQLENRILNQTADMLQLASKYKDLE
Sbjct: 121 KLLRKESRNMNSRVTQLYMQLLHEIIRKRDNALELSQLENRILNQTADMLQLASKYKDLE 180
Query: 181 HKYQHLATLAHNQSEIIAQLEEHCQRVPSARPVPQPPPAAPPRVYQPPTYNRIINQISTN 240
HKYQHLATLAHNQSEIIAQLEEHCQRVPSARPVPQPPPAAPPRVYQPPTYNRIINQISTN
Sbjct: 181 HKYQHLATLAHNQSEIIAQLEEHCQRVPSARPVPQPPPAAPPRVYQPPTYNRIINQISTN 240
Query: 241 EIQSDQNLKVLPPPLPTMPTLTSLPSSTDKPSGPWRDCLQALEDGHDTSSIYLVKPENTN 300
EIQSDQNLKVLPPPLPTMPTLTSLPSSTDKPSGPWRDCLQALEDGHDTSSIYLVKPENTN
Sbjct: 241 EIQSDQNLKVLPPPLPTMPTLTSLPSSTDKPSGPWRDCLQALEDGHDTSSIYLVKPENTN 300
Query: 301 RLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRNWETYKQGFGNIDGEYWLGLENIYWLTNQ 360
RLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRNWETYKQGFGNIDGEYWLGLENIYWLTNQ
Sbjct: 301 RLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRNWETYKQGFGNIDGEYWLGLENIYWLTNQ 360
Query: 361 GNYKLLVTMEDWSGRKVFAEYASFRLEPESEYYKLRLGRYHGNAGDSFTWHNGKQFTTLD 420
GNYKLLVTMEDWSGRKVFAEYASFRLEPESEYYKLRLGRYHGNAGDSFTWHNGKQFTTLD
Sbjct: 361 GNYKLLVTMEDWSGRKVFAEYASFRLEPESEYYKLRLGRYHGNAGDSFTWHNGKQFTTLD 420
Query: 421 RDHDVYTGNCAHYQKGGWWYNACAHSNLNGVWYRGGHYRSRYQDGVYWAEFRGGSYSLKK 480
RDHDVYTGNCAHYQKGGWWYNACAHSNLNGVWYRGGHYRSRYQDGVYWAEFRGGSYSLKK
Sbjct: 421 RDHDVYTGNCAHYQKGGWWYNACAHSNLNGVWYRGGHYRSRYQDGVYWAEFRGGSYSLKK 480
Query: 481 VVMMIRPNPNTFH 493
VVMMIRPNPNTFH
Sbjct: 481 VVMMIRPNPNTFH 493
>gi|4757752 angiopoietin-like 1 precursor [Homo sapiens]
Length = 491
Score = 580 bits (1496), Expect = e-166
Identities = 282/457 (61%), Positives = 349/457 (76%), Gaps = 14/457 (3%)
Query: 43 RYKRAGESQD---KCTYTFIVPQQRVTGAICVNSKEPEV-LLENRVHKQELELLNNELLK 98
RY RA + ++ KC YTF+VP+QR+TG ICVN+K + +++ + + +LE L + L +
Sbjct: 35 RYPRATDGKEEAKKCAYTFLVPEQRITGPICVNTKGQDASTIKDMITRMDLENLKDVLSR 94
Query: 99 QKRQIETLQQLVEVDGGIVSEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNALELSQL 158
QKR+I+ LQ +V+VDG IV+EVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDN+LELSQL
Sbjct: 95 QKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQL 154
Query: 159 ENRILNQTADMLQLASKYKDLEHKYQHLATLAHNQSEIIAQLEEHCQRVPSARPVPQPPP 218
EN+ILN T +ML++A++Y++LE KY L L +NQS +I LEE C R+ S + PP
Sbjct: 155 ENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDTHVSPP 214
Query: 219 ---AAPPRVYQPPTYNRIINQISTNEIQSDQNLK--VLPPP-LPTMPTLT--SLPSSTDK 270
P + Y + + NEIQ D ++PPP L T PT + +P T
Sbjct: 215 LVQVVPQHIPNSQQYTPGL--LGGNEIQRDPGYPRDLMPPPDLATSPTKSPFKIPPVTFI 272
Query: 271 PSGPWRDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFF 330
GP++DC QA E GH S IY++KPEN+N MQ+WC+ DPGGWTVIQ+R DGSVNFF
Sbjct: 273 NEGPFKDCQQAKEAGHSVSGIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFF 332
Query: 331 RNWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRLEPES 390
RNWE YK+GFGNIDGEYWLGLENIY L+NQ NYKLL+ +EDWS +KV+AEY+SFRLEPES
Sbjct: 333 RNWENYKKGFGNIDGEYWLGLENIYMLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPES 392
Query: 391 EYYKLRLGRYHGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAHSNLNG 450
E+Y+LRLG Y GNAGDS WHNGKQFTTLDRD D+Y GNCAH+ KGGWWYNACAHSNLNG
Sbjct: 393 EFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNG 452
Query: 451 VWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRP 487
VWYRGGHYRS++QDG++WAE+RGGSYSL+ V MMI+P
Sbjct: 453 VWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKP 489
>gi|29893555 angiopoietin-like 6 [Homo sapiens]
Length = 470
Score = 418 bits (1074), Expect = e-117
Identities = 213/460 (46%), Positives = 286/460 (62%), Gaps = 27/460 (5%)
Query: 44 YKRAGESQDKCTYTFIVPQQRVTGAICVNSKEPEVLLENRVHKQELELLNNELLKQKRQI 103
+ RAG +CTYTF++P Q+ TGA+C + + EL L + + + +
Sbjct: 19 WARAGAP--RCTYTFVLPPQKFTGAVCWSGPASTRATPEAANASELAALRMRVGRHEELL 76
Query: 104 ETLQQLVEVDGGIVSEVKLLRKESRNMNSRVTQLYMQLLHEI--------IRKRDNALEL 155
LQ+L DG + EV+ LRKESR +++R+ QL QL HE + A L
Sbjct: 77 RELQRLAAADGAVAGEVRALRKESRGLSARLGQLRAQLQHEAGPGAGPGADLGAEPAAAL 136
Query: 156 SQLENRILNQTADMLQLASKYKDLEHKYQHLATLAHNQSEIIAQLEEHCQRVPSARPVPQ 215
+ L R+LN +A+ + A+++ L+ K++ LA L QS +IA+LE C +
Sbjct: 137 ALLGERVLNASAEAQRAAARFHQLDVKFRELAQLVTQQSSLIARLERLCPGGAGGQQQVL 196
Query: 216 PPPAAPPRVYQPPTYNRIINQISTN--------EIQSDQNLKVLPPPLPTMPTLTSLPSS 267
PPP P V P R++ S E Q DQ + P MP P+
Sbjct: 197 PPPPLVPVV---PV--RLVGSTSDTSRMLDPAPEPQRDQTQRQQEPMASPMPA--GHPAV 249
Query: 268 TDKPSGPWRDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSV 327
KP GPW+DC +A + GH+ S +Y ++ ++ VWC+Q+ + GGWTVIQRR DGSV
Sbjct: 250 PTKPVGPWQDCAEARQAGHEQSGVYELRVGR--HVVSVWCEQQLEGGGWTVIQRRQDGSV 307
Query: 328 NFFRNWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRLE 387
NFF W+ YK GFG DGEYWLGLE +Y LT++G+++LLV +EDW GR A Y F LE
Sbjct: 308 NFFTTWQHYKAGFGRPDGEYWLGLEPVYQLTSRGDHELLVLLEDWGGRGARAHYDGFSLE 367
Query: 388 PESEYYKLRLGRYHGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAHSN 447
PES++Y+LRLG+YHG+AGDS +WHN K F+T+DRD D Y+GNCA YQ+GGWWY+ACAHSN
Sbjct: 368 PESDHYRLRLGQYHGDAGDSLSWHNDKPFSTVDRDRDSYSGNCALYQRGGWWYHACAHSN 427
Query: 448 LNGVWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRP 487
LNGVW+ GGHYRSRYQDGVYWAEFRGG+YSL+K M+IRP
Sbjct: 428 LNGVWHHGGHYRSRYQDGVYWAEFRGGAYSLRKAAMLIRP 467
>gi|223029463 fibrinogen C domain containing 1 [Homo sapiens]
Length = 461
Score = 211 bits (536), Expect = 2e-54
Identities = 104/217 (47%), Positives = 129/217 (59%), Gaps = 7/217 (3%)
Query: 276 RDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRNWET 335
RDCL L G +Y V P + QV+CD R D GGWTV QRR DGSVNFFR W+
Sbjct: 242 RDCLDVLLSGQQDDGVYSVFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWDA 301
Query: 336 YKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYAS-----FRLEPES 390
Y+ GFG + GE+WLGL+ I+ LT Q Y+L V +ED+ +A Y S F ++PE
Sbjct: 302 YRDGFGRLTGEHWLGLKRIHALTTQAAYELHVDLEDFENGTAYARYGSFGVGLFSVDPEE 361
Query: 391 EYYKLRLGRYHGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAHSNLNG 450
+ Y L + Y G AGDS H+G +FTT DRD D NCA + +G WWY C SNLNG
Sbjct: 362 DGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNG 421
Query: 451 VWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRP 487
+ RG H + Y DGV W+ + G YSLK M IRP
Sbjct: 422 QYLRGAH--ASYADGVEWSSWTGWQYSLKFSEMKIRP 456
>gi|223029461 fibrinogen C domain containing 1 [Homo sapiens]
Length = 461
Score = 211 bits (536), Expect = 2e-54
Identities = 104/217 (47%), Positives = 129/217 (59%), Gaps = 7/217 (3%)
Query: 276 RDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRNWET 335
RDCL L G +Y V P + QV+CD R D GGWTV QRR DGSVNFFR W+
Sbjct: 242 RDCLDVLLSGQQDDGVYSVFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWDA 301
Query: 336 YKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYAS-----FRLEPES 390
Y+ GFG + GE+WLGL+ I+ LT Q Y+L V +ED+ +A Y S F ++PE
Sbjct: 302 YRDGFGRLTGEHWLGLKRIHALTTQAAYELHVDLEDFENGTAYARYGSFGVGLFSVDPEE 361
Query: 391 EYYKLRLGRYHGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAHSNLNG 450
+ Y L + Y G AGDS H+G +FTT DRD D NCA + +G WWY C SNLNG
Sbjct: 362 DGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNG 421
Query: 451 VWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRP 487
+ RG H + Y DGV W+ + G YSLK M IRP
Sbjct: 422 QYLRGAH--ASYADGVEWSSWTGWQYSLKFSEMKIRP 456
>gi|20532340 angiopoietin 1 [Homo sapiens]
Length = 498
Score = 207 bits (527), Expect = 2e-53
Identities = 143/482 (29%), Positives = 234/482 (48%), Gaps = 55/482 (11%)
Query: 43 RYKRAGESQDKCTYTFIVPQ-----------QRVTGAICVNSK--EPEVLLENRVH---- 85
RY R Q C YTFI+P+ Q T A+ ++ EP+ + H
Sbjct: 32 RYNRIQHGQ--CAYTFILPEHDGNCRESTTDQYNTNALQRDAPHVEPDFSSQKLQHLEHV 89
Query: 86 ----KQELELLNNELLKQ-KRQIETLQQ---------LVEVDGGIVSEVKLLRKESRNMN 131
Q L+ L N +++ K ++ +QQ ++E+ ++S+ +++R +
Sbjct: 90 MENYTQWLQKLENYIVENMKSEMAQIQQNAVQNHTATMLEIGTSLLSQTA---EQTRKLT 146
Query: 132 SRVTQLYMQLLHEIIRKRDNALELSQLENRILNQTADMLQLASKYKDLEHKYQHLATLAH 191
TQ+ Q I+ +N+L +LE ++L QT ++L++ K LEHK +
Sbjct: 147 DVETQVLNQTSRLEIQLLENSLSTYKLEKQLLQQTNEILKIHEKNSLLEHKILEMEGKHK 206
Query: 192 NQSEIIAQLEEHCQRVPSARPVPQPPPAAPPRVYQPPTYNRIINQISTNE-IQSDQNLKV 250
+ + + + +E+ Q + + + Y + +N+ +TN + Q L++
Sbjct: 207 EELDTLKEEKENLQGLVTRQ------------TYIIQELEKQLNRATTNNSVLQKQQLEL 254
Query: 251 LPPPLPTMPTLTS----LPSSTDKPSGPWRDCLQALEDGHDTSSIYLVKPENTNRLMQVW 306
+ + T L + P+RDC + G + S IY + N +V+
Sbjct: 255 MDTVHNLVNLCTKEGVLLKGGKREEEKPFRDCADVYQAGFNKSGIYTIYINNMPEPKKVF 314
Query: 307 CDQRHDPGGWTVIQRRLDGSVNFFRNWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLL 366
C+ + GGWTVIQ R DGS++F R W+ YK GFGN GEYWLG E I+ +T+Q Y L
Sbjct: 315 CNMDVNGGGWTVIQHREDGSLDFQRGWKEYKMGFGNPSGEYWLGNEFIFAITSQRQYMLR 374
Query: 367 VTMEDWSGRKVFAEYASFRLEPESEYYKLRLGRYHGNAG-DSFTWHNGKQFTTLDRDHDV 425
+ + DW G + +++Y F + E + Y+L L + G AG S +G F+T D D+D
Sbjct: 375 IELMDWEGNRAYSQYDRFHIGNEKQNYRLYLKGHTGTAGKQSSLILHGADFSTKDADNDN 434
Query: 426 YTGNCAHYQKGGWWYNACAHSNLNGVWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMI 485
CA GGWW++AC SNLNG++Y G + +G+ W F+G SYSL+ MMI
Sbjct: 435 CMCKCALMLTGGWWFDACGPSNLNGMFYTAGQNHGKL-NGIKWHYFKGPSYSLRSTTMMI 493
Query: 486 RP 487
RP
Sbjct: 494 RP 495
>gi|4557315 angiopoietin 2 isoform a precursor [Homo sapiens]
Length = 496
Score = 207 bits (526), Expect = 2e-53
Identities = 139/473 (29%), Positives = 229/473 (48%), Gaps = 59/473 (12%)
Query: 54 CTYTFIVPQ----QRVTGAICVNSKEPEVLLENRVHKQELELLNNE-------LLK---- 98
C+YTF++P+ + + N+ + + LE Q L++L N L+K
Sbjct: 41 CSYTFLLPEMDNCRSSSSPYVSNAVQRDAPLEYDDSVQRLQVLENIMENNTQWLMKLENY 100
Query: 99 -----QKRQIETLQQLVEVDGGIVSEVKL-LRKESRNMNSRVTQLYMQLLHEIIRKR--- 149
+K +E Q V+ ++ E+ L ++ ++T + Q+L++ R
Sbjct: 101 IQDNMKKEMVEIQQNAVQNQTAVMIEIGTNLLNQTAEQTRKLTDVEAQVLNQTTRLELQL 160
Query: 150 -DNALELSQLENRILNQTADMLQLASKYKDLEHKYQHLATLAHNQSEIIAQLEEHCQRVP 208
+++L ++LE +IL+QT+++ +L K LE K + Q + I + ++ Q +
Sbjct: 161 LEHSLSTNKLEKQILDQTSEINKLQDKNSFLEKKVLAMEDKHIIQLQSIKEEKDQLQVLV 220
Query: 209 SARPVPQPPPAAPPRVYQPPTYNRIINQISTNEIQSDQNLKVLPPP----LPTMPTLTSL 264
S + N II ++ + + N VL + T+ L ++
Sbjct: 221 SKQ-------------------NSIIEELEKKIVTATVNNSVLQKQQHDLMETVNNLLTM 261
Query: 265 PSSTDKPSGP---------WRDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGG 315
S+++ P +RDC + + GH T+ IY + N+ ++ +CD GG
Sbjct: 262 MSTSNSAKDPTVAKEEQISFRDCAEVFKSGHTTNGIYTLTFPNSTEEIKAYCDMEAGGGG 321
Query: 316 WTVIQRRLDGSVNFFRNWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGR 375
WT+IQRR DGSV+F R W+ YK GFGN GEYWLG E + LTNQ Y L + ++DW G
Sbjct: 322 WTIIQRREDGSVDFQRTWKEYKVGFGNPSGEYWLGNEFVSQLTNQQRYVLKIHLKDWEGN 381
Query: 376 KVFAEYASFRLEPESEYYKLRLGRYHGNAGD-SFTWHNGKQFTTLDRDHDVYTGNCAHYQ 434
+ ++ Y F L E Y++ L G AG S G F+T D D+D C+
Sbjct: 382 EAYSLYEHFYLSSEELNYRIHLKGLTGTAGKISSISQPGNDFSTKDGDNDKCICKCSQML 441
Query: 435 KGGWWYNACAHSNLNGVWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRP 487
GGWW++AC SNLNG++Y +++ +G+ W ++G YSLK MMIRP
Sbjct: 442 TGGWWFDACGPSNLNGMYYPQRQNTNKF-NGIKWYYWKGSGYSLKATTMMIRP 493
>gi|169646749 angiopoietin 2 isoform b precursor [Homo sapiens]
Length = 495
Score = 204 bits (520), Expect = 1e-52
Identities = 138/463 (29%), Positives = 226/463 (48%), Gaps = 40/463 (8%)
Query: 54 CTYTFIVPQ----QRVTGAICVNSKEPEVLLENRVHKQELELLNNE-------LLK---- 98
C+YTF++P+ + + N+ + + LE Q L++L N L+K
Sbjct: 41 CSYTFLLPEMDNCRSSSSPYVSNAVQRDAPLEYDDSVQRLQVLENIMENNTQWLMKLENY 100
Query: 99 -----QKRQIETLQQLVEVDGGIVSEVKL-LRKESRNMNSRVTQLYMQLLHEIIRKR--- 149
+K +E Q V+ ++ E+ L ++ ++T + Q+L++ R
Sbjct: 101 IQDNMKKEMVEIQQNAVQNQTAVMIEIGTNLLNQTAEQTRKLTDVEAQVLNQTTRLELQL 160
Query: 150 -DNALELSQLENRILNQTADMLQLASKYKDLEHKYQHLATLAHNQSEIIAQLEEHCQRVP 208
+++L ++LE +IL+QT+++ +L K LE K LA II Q +
Sbjct: 161 LEHSLSTNKLEKQILDQTSEINKLQDKNSFLEKK-----VLAMEDKHII-----QLQSIK 210
Query: 209 SARPVPQPPPAAPPRVYQPPTYNRIINQISTNEIQSDQN--LKVLPPPLPTMPTLTSL-P 265
+ Q + + + + ++ + +Q Q+ ++ + L M T S P
Sbjct: 211 EEKDQLQVLVSKQNSIIEELEKKIVTATVNNSVLQKQQHDLMETVNNLLTMMSTSNSKDP 270
Query: 266 SSTDKPSGPWRDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDG 325
+ + +RDC + + GH T+ IY + N+ ++ +CD GGWT+IQRR DG
Sbjct: 271 TVAKEEQISFRDCAEVFKSGHTTNGIYTLTFPNSTEEIKAYCDMEAGGGGWTIIQRREDG 330
Query: 326 SVNFFRNWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFR 385
SV+F R W+ YK GFGN GEYWLG E + LTNQ Y L + ++DW G + ++ Y F
Sbjct: 331 SVDFQRTWKEYKVGFGNPSGEYWLGNEFVSQLTNQQRYVLKIHLKDWEGNEAYSLYEHFY 390
Query: 386 LEPESEYYKLRLGRYHGNAGD-SFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACA 444
L E Y++ L G AG S G F+T D D+D C+ GGWW++AC
Sbjct: 391 LSSEELNYRIHLKGLTGTAGKISSISQPGNDFSTKDGDNDKCICKCSQMLTGGWWFDACG 450
Query: 445 HSNLNGVWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRP 487
SNLNG++Y +++ +G+ W ++G YSLK MMIRP
Sbjct: 451 PSNLNGMYYPQRQNTNKF-NGIKWYYWKGSGYSLKATTMMIRP 492
>gi|42544202 fibrinogen-like 1 precursor [Homo sapiens]
Length = 312
Score = 204 bits (518), Expect = 2e-52
Identities = 100/228 (43%), Positives = 135/228 (59%), Gaps = 16/228 (7%)
Query: 275 WRDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRNWE 334
+ DC + DG+ S Y +KP + V+CD D GGWTVIQRR DGS NF R W+
Sbjct: 80 YADCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDMS-DGGGWTVIQRRSDGSENFNRGWK 138
Query: 335 TYKQGFGNI---DGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRLEPESE 391
Y+ GFGN GEYWLG +N+++LT Q +Y L + + D+ +A+Y +F++ E
Sbjct: 139 DYENGFGNFVQKHGEYWLGNKNLHFLTTQEDYTLKIDLADFEKNSRYAQYKNFKVGDEKN 198
Query: 392 YYKLRLGRYHGNAGDSFT--------W---HNGKQFTTLDRDHDVYTGNCAHYQKGGWWY 440
+Y+L +G Y G AGDS W H +F+T DRDHD Y GNCA + GWW+
Sbjct: 199 FYELNIGEYSGTAGDSLAGNFHPEVQWWASHQRMKFSTWDRDHDNYEGNCAEEDQSGWWF 258
Query: 441 NACAHSNLNGVWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRPN 488
N C +NLNGV+Y G Y ++ +G+ W + G YSLK VVM IRPN
Sbjct: 259 NRCHSANLNGVYY-SGPYTAKTDNGIVWYTWHGWWYSLKSVVMKIRPN 305
>gi|42544200 fibrinogen-like 1 precursor [Homo sapiens]
Length = 312
Score = 204 bits (518), Expect = 2e-52
Identities = 100/228 (43%), Positives = 135/228 (59%), Gaps = 16/228 (7%)
Query: 275 WRDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRNWE 334
+ DC + DG+ S Y +KP + V+CD D GGWTVIQRR DGS NF R W+
Sbjct: 80 YADCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDMS-DGGGWTVIQRRSDGSENFNRGWK 138
Query: 335 TYKQGFGNI---DGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRLEPESE 391
Y+ GFGN GEYWLG +N+++LT Q +Y L + + D+ +A+Y +F++ E
Sbjct: 139 DYENGFGNFVQKHGEYWLGNKNLHFLTTQEDYTLKIDLADFEKNSRYAQYKNFKVGDEKN 198
Query: 392 YYKLRLGRYHGNAGDSFT--------W---HNGKQFTTLDRDHDVYTGNCAHYQKGGWWY 440
+Y+L +G Y G AGDS W H +F+T DRDHD Y GNCA + GWW+
Sbjct: 199 FYELNIGEYSGTAGDSLAGNFHPEVQWWASHQRMKFSTWDRDHDNYEGNCAEEDQSGWWF 258
Query: 441 NACAHSNLNGVWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRPN 488
N C +NLNGV+Y G Y ++ +G+ W + G YSLK VVM IRPN
Sbjct: 259 NRCHSANLNGVYY-SGPYTAKTDNGIVWYTWHGWWYSLKSVVMKIRPN 305
>gi|42544198 fibrinogen-like 1 precursor [Homo sapiens]
Length = 312
Score = 204 bits (518), Expect = 2e-52
Identities = 100/228 (43%), Positives = 135/228 (59%), Gaps = 16/228 (7%)
Query: 275 WRDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRNWE 334
+ DC + DG+ S Y +KP + V+CD D GGWTVIQRR DGS NF R W+
Sbjct: 80 YADCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDMS-DGGGWTVIQRRSDGSENFNRGWK 138
Query: 335 TYKQGFGNI---DGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRLEPESE 391
Y+ GFGN GEYWLG +N+++LT Q +Y L + + D+ +A+Y +F++ E
Sbjct: 139 DYENGFGNFVQKHGEYWLGNKNLHFLTTQEDYTLKIDLADFEKNSRYAQYKNFKVGDEKN 198
Query: 392 YYKLRLGRYHGNAGDSFT--------W---HNGKQFTTLDRDHDVYTGNCAHYQKGGWWY 440
+Y+L +G Y G AGDS W H +F+T DRDHD Y GNCA + GWW+
Sbjct: 199 FYELNIGEYSGTAGDSLAGNFHPEVQWWASHQRMKFSTWDRDHDNYEGNCAEEDQSGWWF 258
Query: 441 NACAHSNLNGVWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRPN 488
N C +NLNGV+Y G Y ++ +G+ W + G YSLK VVM IRPN
Sbjct: 259 NRCHSANLNGVYY-SGPYTAKTDNGIVWYTWHGWWYSLKSVVMKIRPN 305
>gi|42544189 fibrinogen-like 1 precursor [Homo sapiens]
Length = 312
Score = 204 bits (518), Expect = 2e-52
Identities = 100/228 (43%), Positives = 135/228 (59%), Gaps = 16/228 (7%)
Query: 275 WRDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRNWE 334
+ DC + DG+ S Y +KP + V+CD D GGWTVIQRR DGS NF R W+
Sbjct: 80 YADCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDMS-DGGGWTVIQRRSDGSENFNRGWK 138
Query: 335 TYKQGFGNI---DGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRLEPESE 391
Y+ GFGN GEYWLG +N+++LT Q +Y L + + D+ +A+Y +F++ E
Sbjct: 139 DYENGFGNFVQKHGEYWLGNKNLHFLTTQEDYTLKIDLADFEKNSRYAQYKNFKVGDEKN 198
Query: 392 YYKLRLGRYHGNAGDSFT--------W---HNGKQFTTLDRDHDVYTGNCAHYQKGGWWY 440
+Y+L +G Y G AGDS W H +F+T DRDHD Y GNCA + GWW+
Sbjct: 199 FYELNIGEYSGTAGDSLAGNFHPEVQWWASHQRMKFSTWDRDHDNYEGNCAEEDQSGWWF 258
Query: 441 NACAHSNLNGVWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRPN 488
N C +NLNGV+Y G Y ++ +G+ W + G YSLK VVM IRPN
Sbjct: 259 NRCHSANLNGVYY-SGPYTAKTDNGIVWYTWHGWWYSLKSVVMKIRPN 305
>gi|169646754 angiopoietin 2 isoform c precursor [Homo sapiens]
Length = 444
Score = 201 bits (510), Expect = 2e-51
Identities = 137/448 (30%), Positives = 220/448 (49%), Gaps = 61/448 (13%)
Query: 54 CTYTFIVPQQRVTGAICVNSKEPEVLLENRVHKQELELLNNELLKQKRQIETLQQLVEVD 113
C+YTF++P+ C +S P V N V + + L+ ++ LQ L +
Sbjct: 41 CSYTFLLPEMDN----CRSSSSPYV--SNAVQR-------DAPLEYDDSVQRLQVLENI- 86
Query: 114 GGIVSEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNALELSQLENRILNQTADMLQLA 173
+ + + L K + ++ T+L +QLL +++L ++LE +IL+QT+++ +L
Sbjct: 87 --MENNTQWLMK----VLNQTTRLELQLL-------EHSLSTNKLEKQILDQTSEINKLQ 133
Query: 174 SKYKDLEHKYQHLATLAHNQSEIIAQLEEHCQRVPSARPVPQPPPAAPPRVYQPPTYNRI 233
K LE K + Q + I + ++ Q + S + N I
Sbjct: 134 DKNSFLEKKVLAMEDKHIIQLQSIKEEKDQLQVLVSKQ-------------------NSI 174
Query: 234 INQISTNEIQSDQNLKVLPPP----LPTMPTLTSLPSSTDKPSGP---------WRDCLQ 280
I ++ + + N VL + T+ L ++ S+++ P +RDC +
Sbjct: 175 IEELEKKIVTATVNNSVLQKQQHDLMETVNNLLTMMSTSNSAKDPTVAKEEQISFRDCAE 234
Query: 281 ALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRNWETYKQGF 340
+ GH T+ IY + N+ ++ +CD GGWT+IQRR DGSV+F R W+ YK GF
Sbjct: 235 VFKSGHTTNGIYTLTFPNSTEEIKAYCDMEAGGGGWTIIQRREDGSVDFQRTWKEYKVGF 294
Query: 341 GNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRLEPESEYYKLRLGRY 400
GN GEYWLG E + LTNQ Y L + ++DW G + ++ Y F L E Y++ L
Sbjct: 295 GNPSGEYWLGNEFVSQLTNQQRYVLKIHLKDWEGNEAYSLYEHFYLSSEELNYRIHLKGL 354
Query: 401 HGNAGD-SFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAHSNLNGVWYRGGHYR 459
G AG S G F+T D D+D C+ GGWW++AC SNLNG++Y
Sbjct: 355 TGTAGKISSISQPGNDFSTKDGDNDKCICKCSQMLTGGWWFDACGPSNLNGMYYPQRQNT 414
Query: 460 SRYQDGVYWAEFRGGSYSLKKVVMMIRP 487
+++ +G+ W ++G YSLK MMIRP
Sbjct: 415 NKF-NGIKWYYWKGSGYSLKATTMMIRP 441
>gi|7705276 angiopoietin 4 [Homo sapiens]
Length = 503
Score = 200 bits (509), Expect = 2e-51
Identities = 145/466 (31%), Positives = 229/466 (49%), Gaps = 40/466 (8%)
Query: 54 CTYTFIVPQQRVTGAICVNSKEPEVL----LENRVH---------KQELELLNNE---LL 97
C+YTF++P+ S++ L L N +H KQ + L N L
Sbjct: 43 CSYTFLLPKSEPCPPGPEVSRDSNTLQRESLANPLHLGKLPTQQVKQLEQALQNNTQWLK 102
Query: 98 KQKRQIETL---------QQLVEVDGGIVSEV--KLLRKESRNMNSRVTQLYMQLLHEII 146
K +R I+T+ QQ+ + + E+ LL + + + ++T + QLL++
Sbjct: 103 KLERAIKTILRSKLEQVQQQMAQNQTAPMLELGTSLLNQTTAQIR-KLTDMEAQLLNQTS 161
Query: 147 RKR----DNALELSQLENRILNQTADMLQLASKYKDLEHKYQHLATLAHNQSEIIAQLEE 202
R + L ++LEN++L Q + QL + LE + Q L T Q E+ + L +
Sbjct: 162 RMDAQMPETFLSTNKLENQLLLQRQKLQQLQGQNSALEKRLQALET--KQQEELASILSK 219
Query: 203 HCQRVPSARPVPQPPPAAPPRVYQPPTYNRIINQISTNEIQSDQNLKVLPPPLPTMPTLT 262
+ + + AA + + R + + ++ S + L VL L
Sbjct: 220 KAKLLNTL----SRQSAALTNIERGLRGVRHNSSLLQDQQHSLRQLLVLLRHLVQERANA 275
Query: 263 SLPSSTDKPSGPWRDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRR 322
S P+ ++DC + G S +Y ++ N + +V+CD + G WT+IQRR
Sbjct: 276 SAPAFIMAGEQVFQDCAEIQRSGASASGVYTIQVSNATKPRKVFCDLQSSGGRWTLIQRR 335
Query: 323 LDGSVNFFRNWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYA 382
+G+VNF RNW+ YKQGFG+ GE+WLG E ++ LT + Y L V ++DW G + +A+Y
Sbjct: 336 ENGTVNFQRNWKDYKQGFGDPAGEHWLGNEVVHQLTRRAAYSLRVELQDWEGHEAYAQYE 395
Query: 383 SFRLEPESEYYKLRLGRYHGNAG-DSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYN 441
F L E++ Y+L + Y G+AG S F+TLD D+D CA GGWW++
Sbjct: 396 HFHLGSENQLYRLSVVGYSGSAGRQSSLVLQNTSFSTLDSDNDHCLCKCAQVMSGGWWFD 455
Query: 442 ACAHSNLNGVWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRP 487
AC SNLNGV+Y + + DG+ W F+G SYSL+ MMIRP
Sbjct: 456 ACGLSNLNGVYYHAPDNKYK-MDGIRWHYFKGPSYSLRASRMMIRP 500
>gi|4503689 fibrinogen, alpha polypeptide isoform alpha-E
preproprotein [Homo sapiens]
Length = 866
Score = 197 bits (501), Expect = 2e-50
Identities = 102/239 (42%), Positives = 143/239 (59%), Gaps = 25/239 (10%)
Query: 272 SGPWRDCLQALED--GHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNF 329
S P RDC L+ S I+ +K ++++ V+CDQ GGW +IQ+R+DGS+NF
Sbjct: 626 SRPVRDCDDVLQTHPSGTQSGIFNIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNF 685
Query: 330 FRNWETYKQGFGNI----DGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFR 385
R W+ YK+GFG++ +GE+WLG + ++ LT +G+ L V +EDW+G + +AEY FR
Sbjct: 686 NRTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQRGSV-LRVELEDWAGNEAYAEY-HFR 743
Query: 386 LEPESEYYKLRLGRYHGNAGDS-----------FTWHNGKQFTTLDRDHDVYTGNCAHYQ 434
+ E+E Y L++ Y G AGD+ +T HN QF+T DRD D + NCA
Sbjct: 744 VGSEAEGYALQVSSYEGTAGDALIEGSVEEGAEYTSHNNMQFSTFDRDADQWEENCAEVY 803
Query: 435 KGGWWYNACAHSNLNGVWYRGGHYRSR------YQDGVYWAEFRGGSYSLKKVVMMIRP 487
GGWWYN C +NLNG++Y GG Y R ++GV W FRG YSL+ V M IRP
Sbjct: 804 GGGWWYNNCQAANLNGIYYPGGSYDPRNNSPYEIENGVVWVSFRGADYSLRAVRMKIRP 862
>gi|10863949 angiopoietin-like 7 [Homo sapiens]
Length = 346
Score = 196 bits (497), Expect = 5e-50
Identities = 96/214 (44%), Positives = 137/214 (64%), Gaps = 5/214 (2%)
Query: 277 DCLQALEDGHDTSSIYLVKPENT--NRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRNWE 334
DC + + S +Y + P++ + ++V+CD GGWT+IQRR G V+F+R+W+
Sbjct: 130 DCSSLYQKNYRISGVYKLPPDDFLGSPELEVFCDMETSGGGWTIIQRRKSGLVSFYRDWK 189
Query: 335 TYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRLEPESEYYK 394
YKQGFG+I G++WLG E+I+ L+ Q +L V MEDW G +AEY+ F L E Y+
Sbjct: 190 QYKQGFGSIRGDFWLGNEHIHRLSRQPT-RLRVEMEDWEGNLRYAEYSHFVLGNELNSYR 248
Query: 395 LRLGRYHGNAG-DSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAHSNLNGVWY 453
L LG Y GN G D+ +HN F+T D+D+D CA +KGG+WYN C SNLNGV+Y
Sbjct: 249 LFLGNYTGNVGNDALQYHNNTAFSTKDKDNDNCLDKCAQLRKGGYWYNCCTDSNLNGVYY 308
Query: 454 RGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRP 487
R G + +++ DG+ W + G +YSLK+V M IRP
Sbjct: 309 RLGEH-NKHLDGITWYGWHGSTYSLKRVEMKIRP 341
>gi|27754778 ficolin 3 isoform 2 precursor [Homo sapiens]
Length = 288
Score = 193 bits (491), Expect = 3e-49
Identities = 100/216 (46%), Positives = 136/216 (62%), Gaps = 7/216 (3%)
Query: 273 GPWRDCLQALEDGHDTSSIY-LVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFR 331
GP R+C + L G S Y L PE R + V+CD + GGW V QRR DGSV+FFR
Sbjct: 78 GP-RNCRELLSQGATLSGWYHLCLPEG--RALPVFCDMDTEGGGWLVFQRRQDGSVDFFR 134
Query: 332 NWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRLEPESE 391
+W +Y+ GFGN + E+WLG EN++ LT QGN++L V +ED++G + FA YA+FRL E +
Sbjct: 135 SWSSYRAGFGNQESEFWLGNENLHQLTLQGNWELRVELEDFNGNRTFAHYATFRLLGEVD 194
Query: 392 YYKLRLGRY-HGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAHSNLNG 450
+Y+L LG++ G AGDS + H+G+ FTT D DHD NCA G WWY +C SNLNG
Sbjct: 195 HYQLALGKFSEGTAGDSLSLHSGRPFTTYDADHDSSNSNCAVIVHGAWWYASCYRSNLNG 254
Query: 451 VWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIR 486
+ +Y G+ WA RG + ++V MM+R
Sbjct: 255 RYAVSEAAAHKY--GIDWASGRGVGHPYRRVRMMLR 288
>gi|27754776 ficolin 3 isoform 1 precursor [Homo sapiens]
Length = 299
Score = 193 bits (491), Expect = 3e-49
Identities = 100/216 (46%), Positives = 136/216 (62%), Gaps = 7/216 (3%)
Query: 273 GPWRDCLQALEDGHDTSSIY-LVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFR 331
GP R+C + L G S Y L PE R + V+CD + GGW V QRR DGSV+FFR
Sbjct: 89 GP-RNCRELLSQGATLSGWYHLCLPEG--RALPVFCDMDTEGGGWLVFQRRQDGSVDFFR 145
Query: 332 NWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRLEPESE 391
+W +Y+ GFGN + E+WLG EN++ LT QGN++L V +ED++G + FA YA+FRL E +
Sbjct: 146 SWSSYRAGFGNQESEFWLGNENLHQLTLQGNWELRVELEDFNGNRTFAHYATFRLLGEVD 205
Query: 392 YYKLRLGRY-HGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAHSNLNG 450
+Y+L LG++ G AGDS + H+G+ FTT D DHD NCA G WWY +C SNLNG
Sbjct: 206 HYQLALGKFSEGTAGDSLSLHSGRPFTTYDADHDSSNSNCAVIVHGAWWYASCYRSNLNG 265
Query: 451 VWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIR 486
+ +Y G+ WA RG + ++V MM+R
Sbjct: 266 RYAVSEAAAHKY--GIDWASGRGVGHPYRRVRMMLR 299
>gi|8051586 ficolin 2 isoform b precursor [Homo sapiens]
Length = 275
Score = 192 bits (489), Expect = 4e-49
Identities = 100/217 (46%), Positives = 137/217 (63%), Gaps = 5/217 (2%)
Query: 272 SGPWRDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFR 331
+GP R C L+ GH S + + + R + V CD D GGWTV QRR+DGSV+F+R
Sbjct: 62 TGP-RTCKDLLDRGHFLSGWHTIYLPDC-RPLTVLCDMDTDGGGWTVFQRRVDGSVDFYR 119
Query: 332 NWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRLEPESE 391
+W TYKQGFG+ GE+WLG +NI+ LT QG +L V + D+ FA+Y SF++ E+E
Sbjct: 120 DWATYKQGFGSRLGEFWLGNDNIHALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAE 179
Query: 392 YYKLRLGRY-HGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAHSNLNG 450
Y L LG + G+AGDS T+HN + F+T D+D+D+ TGNCA +G WWY C SNLNG
Sbjct: 180 KYNLVLGAFVEGSAGDSLTFHNNQSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLNG 239
Query: 451 VWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRP 487
+ RG H + +G+ W +G +YS K M +RP
Sbjct: 240 RYLRGTH--GSFANGINWKSGKGYNYSYKVSEMKVRP 274
>gi|61744445 ficolin 2 isoform a precursor [Homo sapiens]
Length = 313
Score = 192 bits (489), Expect = 4e-49
Identities = 100/217 (46%), Positives = 137/217 (63%), Gaps = 5/217 (2%)
Query: 272 SGPWRDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFR 331
+GP R C L+ GH S + + + R + V CD D GGWTV QRR+DGSV+F+R
Sbjct: 100 TGP-RTCKDLLDRGHFLSGWHTIYLPDC-RPLTVLCDMDTDGGGWTVFQRRVDGSVDFYR 157
Query: 332 NWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRLEPESE 391
+W TYKQGFG+ GE+WLG +NI+ LT QG +L V + D+ FA+Y SF++ E+E
Sbjct: 158 DWATYKQGFGSRLGEFWLGNDNIHALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAE 217
Query: 392 YYKLRLGRY-HGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAHSNLNG 450
Y L LG + G+AGDS T+HN + F+T D+D+D+ TGNCA +G WWY C SNLNG
Sbjct: 218 KYNLVLGAFVEGSAGDSLTFHNNQSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLNG 277
Query: 451 VWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRP 487
+ RG H + +G+ W +G +YS K M +RP
Sbjct: 278 RYLRGTH--GSFANGINWKSGKGYNYSYKVSEMKVRP 312
>gi|157384973 tenascin R [Homo sapiens]
Length = 1358
Score = 191 bits (485), Expect = 1e-48
Identities = 92/213 (43%), Positives = 128/213 (60%), Gaps = 7/213 (3%)
Query: 276 RDCLQALEDGHDTSSIY-LVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRNWE 334
+DC Q L +G S +Y + ++ +QV+CD D GGW V QRR +G +FFR W
Sbjct: 1136 QDCAQHLMNGDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWA 1195
Query: 335 TYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRLEPESEYYK 394
Y+ GFGN++ E+WLGL+NI+ +T+QG Y+L V M D FA Y F +E YK
Sbjct: 1196 DYRVGFGNVEDEFWLGLDNIHRITSQGRYELRVDMRD-GQEAAFASYDRFSVEDSRNLYK 1254
Query: 395 LRLGRYHGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAHSNLNGVWYR 454
LR+G Y+G AGDS ++H G+ F+T DRD+DV NCA KG WWY C +NLN
Sbjct: 1255 LRIGSYNGTAGDSLSYHQGRPFSTEDRDNDVAVTNCAMSYKGAWWYKNCHRTNLN----- 1309
Query: 455 GGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRP 487
G + SR+ G+ W ++G +S+ V M +RP
Sbjct: 1310 GKYGESRHSQGINWYHWKGHEFSIPFVEMKMRP 1342
>gi|70906435 fibrinogen, beta chain preproprotein [Homo sapiens]
Length = 491
Score = 190 bits (483), Expect = 2e-48
Identities = 97/248 (39%), Positives = 140/248 (56%), Gaps = 36/248 (14%)
Query: 276 RDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRNWET 335
++C + + G +TS +YL++P+++ + +V+CD + GGWTVIQ R DGSV+F R W+
Sbjct: 239 KECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDP 298
Query: 336 YKQGFGNI------------DGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYAS 383
YKQGFGN+ GEYWLG + I LT G +LL+ MEDW G KV A Y
Sbjct: 299 YKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGG 358
Query: 384 FRLEPESEYYKLRLGRYHGNAGD--------------SFTWHNGKQFTTLDRDHDVYTGN 429
F ++ E+ Y++ + +Y G AG+ + T HNG F+T DRD+D + +
Sbjct: 359 FTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTS 418
Query: 430 -----CAHYQKGGWWYNACAHSNLNGVWYRGGHY-----RSRYQDGVYWAEFRGGSYSLK 479
C+ GGWWYN C +N NG +Y GG Y + DGV W ++G YS++
Sbjct: 419 DPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMR 478
Query: 480 KVVMMIRP 487
K+ M IRP
Sbjct: 479 KMSMKIRP 486
>gi|8051584 ficolin 1 precursor [Homo sapiens]
Length = 326
Score = 188 bits (478), Expect = 8e-48
Identities = 98/217 (45%), Positives = 137/217 (63%), Gaps = 5/217 (2%)
Query: 272 SGPWRDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFR 331
+GP R+C L+ G+ S + + + R + V CD D GGWTV QRR+DGSV+F+R
Sbjct: 113 TGP-RNCKDLLDRGYFLSGWHTIYLPDC-RPLTVLCDMDTDGGGWTVFQRRMDGSVDFYR 170
Query: 332 NWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRLEPESE 391
+W YKQGFG+ GE+WLG +NI+ LT QG+ +L V + D+ G FA+Y SF++ E+E
Sbjct: 171 DWAAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRVDLVDFEGNHQFAKYKSFKVADEAE 230
Query: 392 YYKLRLGRY-HGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAHSNLNG 450
YKL LG + G+AG+S T HN F+T D+D+DV + NCA +G WWY C SNLNG
Sbjct: 231 KYKLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNG 290
Query: 451 VWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRP 487
++ G H Y +G+ W+ +G YS K M +RP
Sbjct: 291 LYLMGPH--ESYANGINWSAAKGYKYSYKVSEMKVRP 325
>gi|23111005 microfibrillar-associated protein 4 [Homo sapiens]
Length = 255
Score = 188 bits (478), Expect = 8e-48
Identities = 88/216 (40%), Positives = 128/216 (59%), Gaps = 8/216 (3%)
Query: 277 DCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRNWETY 336
DC G+ + +YL+ P + + V+CD + G WTV Q+R +GSV+FFR W Y
Sbjct: 40 DCDDIYAQGYQSDGVYLIYPSGPSVPVPVFCDMTTEGGKWTVFQKRFNGSVSFFRGWNDY 99
Query: 337 KQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRLEP------ES 390
K GFG DGEYWLGL+N++ LT + Y+L V +ED+ +A+YA F + P E
Sbjct: 100 KLGFGRADGEYWLGLQNMHLLTLKQKYELRVDLEDFENNTAYAKYADFSISPNAVSAEED 159
Query: 391 EYYKLRLGRYHGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAHSNLNG 450
Y G G AGDS ++H+G++F+T DRD D++ NCA G +W+ +C +NLNG
Sbjct: 160 GYTLFVAGFEDGGAGDSLSYHSGQKFSTFDRDQDLFVQNCAALSSGAFWFRSCHFANLNG 219
Query: 451 VWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIR 486
+ G H Y +G+ WA+++G YSLK+ M IR
Sbjct: 220 FYLGGSHL--SYANGINWAQWKGFYYSLKRTEMKIR 253
>gi|70906439 fibrinogen, gamma chain isoform gamma-B precursor [Homo
sapiens]
Length = 453
Score = 182 bits (463), Expect = 5e-46
Identities = 95/238 (39%), Positives = 134/238 (56%), Gaps = 26/238 (10%)
Query: 276 RDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRNWET 335
+DC G S +Y +KP N+ V+C+ GWTV Q+RLDGSV+F +NW
Sbjct: 177 KDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQ 236
Query: 336 YKQGFGNIDG----EYWLGLENIYWLTNQGN--YKLLVTMEDWSGRKVFAEYASFRLEPE 389
YK+GFG++ E+WLG E I+ ++ Q Y L V +EDW+GR A+YA F++ PE
Sbjct: 237 YKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPE 296
Query: 390 SEYYKLRLGRYHG-NAGDSF--------------TWHNGKQFTTLDRDHDVYTGNCAHYQ 434
++ Y+L + G +AGD+F T HNG QF+T D D+D + GNCA
Sbjct: 297 ADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQD 356
Query: 435 KGGWWYNACAHSNLNGVWYRGGHYR-----SRYQDGVYWAEFRGGSYSLKKVVMMIRP 487
GWW N C +LNGV+Y+GG Y + Y +G+ WA ++ YS+KK M I P
Sbjct: 357 GSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIP 414
>gi|70906437 fibrinogen, gamma chain isoform gamma-A precursor [Homo
sapiens]
Length = 437
Score = 182 bits (463), Expect = 5e-46
Identities = 95/238 (39%), Positives = 134/238 (56%), Gaps = 26/238 (10%)
Query: 276 RDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRNWET 335
+DC G S +Y +KP N+ V+C+ GWTV Q+RLDGSV+F +NW
Sbjct: 177 KDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQ 236
Query: 336 YKQGFGNIDG----EYWLGLENIYWLTNQGN--YKLLVTMEDWSGRKVFAEYASFRLEPE 389
YK+GFG++ E+WLG E I+ ++ Q Y L V +EDW+GR A+YA F++ PE
Sbjct: 237 YKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPE 296
Query: 390 SEYYKLRLGRYHG-NAGDSF--------------TWHNGKQFTTLDRDHDVYTGNCAHYQ 434
++ Y+L + G +AGD+F T HNG QF+T D D+D + GNCA
Sbjct: 297 ADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQD 356
Query: 435 KGGWWYNACAHSNLNGVWYRGGHYR-----SRYQDGVYWAEFRGGSYSLKKVVMMIRP 487
GWW N C +LNGV+Y+GG Y + Y +G+ WA ++ YS+KK M I P
Sbjct: 357 GSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIP 414
>gi|5730075 fibrinogen-like 2 precursor [Homo sapiens]
Length = 439
Score = 173 bits (438), Expect = 4e-43
Identities = 92/228 (40%), Positives = 132/228 (57%), Gaps = 18/228 (7%)
Query: 275 WRDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRNWE 334
++DC G +S Y V P+ N +V+CD GGWTV+Q RLDGS NF R W+
Sbjct: 210 YKDCSDYYAIGKRSSETYRVTPDPKNSSFEVYCDMETMGGGWTVLQARLDGSTNFTRTWQ 269
Query: 335 TYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRLEPESEYYK 394
YK GFGN+ E+WLG + I+ LT L + +ED++G +++A Y F + E Y+
Sbjct: 270 DYKAGFGNLRREFWLGNDKIHLLTKSKEMILRIDLEDFNGVELYALYDQFYVANEFLKYR 329
Query: 395 LRLGRYHGNAGDSFTW-----HNGKQFTTLDRDHDVY-TGNCAHYQKGGWWYNACAHSNL 448
L +G Y+G AGD+ + H+ K FTT D+D+D Y +GNC Y GWW++AC +NL
Sbjct: 330 LHVGNYNGTAGDALRFNKHYNHDLKFFTTPDKDNDRYPSGNCGLYYSSGWWFDACLSANL 389
Query: 449 NGVWYRGGHYRSR-YQDGVYWAEFRG------GSY--SLKKVVMMIRP 487
NG +Y H + R ++G++W + G G Y S K+ MMIRP
Sbjct: 390 NGKYY---HQKYRGVRNGIFWGTWPGVSEAHPGGYKSSFKEAKMMIRP 434
>gi|20665034 tenascin XB isoform 2 [Homo sapiens]
Length = 673
Score = 172 bits (437), Expect = 5e-43
Identities = 87/215 (40%), Positives = 128/215 (59%), Gaps = 11/215 (5%)
Query: 276 RDCLQALEDGHD---TSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRN 332
RDC + +++G TS+I+L N R + V+CD D GGW V QRR+DG +F+R+
Sbjct: 457 RDCGEEMQNGAGASRTSTIFL--NGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRD 514
Query: 333 WETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRLEPESEY 392
WE Y GFGNI GE+WLG E ++ LT G+Y + V + VFA+Y SF ++ +EY
Sbjct: 515 WEDYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLRA-GDEAVFAQYDSFHVDSAAEY 573
Query: 393 YKLRLGRYHGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAHSNLNGVW 452
Y+L L YHG AGDS ++H+G F+ DRD + +CA +G WWY C ++NLNG++
Sbjct: 574 YRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLY 633
Query: 453 YRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRP 487
++ GV W ++G +S+ M +RP
Sbjct: 634 GSTVDHQ-----GVSWYHWKGFEFSVPFTEMKLRP 663
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 172 bits (437), Expect = 5e-43
Identities = 87/215 (40%), Positives = 128/215 (59%), Gaps = 11/215 (5%)
Query: 276 RDCLQALEDGHD---TSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRN 332
RDC + +++G TS+I+L N R + V+CD D GGW V QRR+DG +F+R+
Sbjct: 4026 RDCGEEMQNGAGASRTSTIFL--NGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRD 4083
Query: 333 WETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRLEPESEY 392
WE Y GFGNI GE+WLG E ++ LT G+Y + V + VFA+Y SF ++ +EY
Sbjct: 4084 WEDYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLRA-GDEAVFAQYDSFHVDSAAEY 4142
Query: 393 YKLRLGRYHGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAHSNLNGVW 452
Y+L L YHG AGDS ++H+G F+ DRD + +CA +G WWY C ++NLNG++
Sbjct: 4143 YRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLY 4202
Query: 453 YRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRP 487
++ GV W ++G +S+ M +RP
Sbjct: 4203 GSTVDHQ-----GVSWYHWKGFEFSVPFTEMKLRP 4232
>gi|62988324 tenascin N [Homo sapiens]
Length = 1299
Score = 165 bits (418), Expect = 8e-41
Identities = 84/232 (36%), Positives = 134/232 (57%), Gaps = 13/232 (5%)
Query: 260 TLTSLPSSTDKPSGPWRDCLQALEDGHDTSSIYLVKPE-NTNRLMQVWCDQRHDPGGWTV 318
TL+++ + PS DC Q ++ + S +Y + + +R +QV+CD D GGW V
Sbjct: 1056 TLSTVGARFPHPS----DCSQVQQNSNAASGLYTIYLHGDASRPLQVYCDMETDGGGWIV 1111
Query: 319 IQRRLDGSVNFFRNWETYKQGFGNIDGEYWLGLENIYWLTN--QGNYKLLVTMEDWSGRK 376
QRR G ++FF+ W +Y +GFG+ E+WLGL+ ++ LT Y++ V ++ +
Sbjct: 1112 FQRRNTGQLDFFKRWRSYVEGFGDPMKEFWLGLDKLHNLTTGTPARYEVRVDLQT-ANES 1170
Query: 377 VFAEYASFRLEPESEYYKLRLGRYHGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKG 436
+A Y F++ E YKL +G+Y G AGD+ T+HNG +FTT DRD+D+ NCA G
Sbjct: 1171 AYAIYDFFQVASSKERYKLTVGKYRGTAGDALTYHNGWKFTTFDRDNDIALSNCALTHHG 1230
Query: 437 GWWYNACAHSNLNGVWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRPN 488
GWWY C +N N G + +++ +GV W ++G +S+ V + IRP+
Sbjct: 1231 GWWYKNCHLANPN-----GRYGETKHSEGVNWEPWKGHEFSIPYVELKIRPH 1277
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,184,320
Number of Sequences: 37866
Number of extensions: 1092629
Number of successful extensions: 9035
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 75
Number of HSP's successfully gapped in prelim test: 299
Number of HSP's that attempted gapping in prelim test: 7696
Number of HSP's gapped (non-prelim): 1301
length of query: 493
length of database: 18,247,518
effective HSP length: 106
effective length of query: 387
effective length of database: 14,233,722
effective search space: 5508450414
effective search space used: 5508450414
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.