Guide to the Human Genome
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Search of human proteins with 68508970

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|68508970 tryptase beta 2 precursor [Homo sapiens]
         (275 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|68508970 tryptase beta 2 precursor [Homo sapiens]                  588   e-168
gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]            581   e-166
gi|11321636 tryptase delta 1 [Homo sapiens]                           432   e-121
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]      235   4e-62
gi|13994276 marapsin [Homo sapiens]                                   226   2e-59
gi|117956391 protease, serine, 33 [Homo sapiens]                      216   2e-56
gi|4506153 prostasin preproprotein [Homo sapiens]                     202   3e-52
gi|11545839 protease, serine, 22 [Homo sapiens]                       199   2e-51
gi|21614531 testisin isoform 2 [Homo sapiens]                         198   4e-51
gi|5803197 testisin isoform 1 [Homo sapiens]                          193   1e-49
gi|116256363 transmembrane protease, serine 13 [Homo sapiens]         184   6e-47
gi|58218970 protease, serine, 36 [Homo sapiens]                       182   3e-46
gi|170932492 transmembrane protease, serine 5 [Homo sapiens]          180   1e-45
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap...   179   2e-45
gi|4503627 coagulation factor XI precursor [Homo sapiens]             179   2e-45
gi|23957702 transmembrane protease, serine 6 [Homo sapiens]           178   5e-45
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]             177   1e-44
gi|148806900 epidermis-specific serine protease-like protein [Ho...   176   2e-44
gi|21614533 testisin isoform 3 [Homo sapiens]                         173   1e-43
gi|205360905 testis-specific serine protease 1 [Homo sapiens]         171   5e-43
gi|4758508 transmembrane protease, serine 11D [Homo sapiens]          171   5e-43
gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens]          171   6e-43
gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo ...   171   6e-43
gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo ...   171   6e-43
gi|110815798 ovochymase 1 [Homo sapiens]                              171   6e-43
gi|15559207 elastase 2A preproprotein [Homo sapiens]                  169   2e-42
gi|118498341 chymotrypsin B1 [Homo sapiens]                           169   3e-42
gi|4505881 plasminogen [Homo sapiens]                                 166   3e-41
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa...   165   5e-41
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa...   165   5e-41

>gi|68508970 tryptase beta 2 precursor [Homo sapiens]
          Length = 275

 Score =  588 bits (1517), Expect = e-168
 Identities = 275/275 (100%), Positives = 275/275 (100%)

Query: 1   MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCG 60
           MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCG
Sbjct: 1   MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCG 60

Query: 61  GSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGA 120
           GSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGA
Sbjct: 61  GSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGA 120

Query: 121 DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV 180
           DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV
Sbjct: 121 DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV 180

Query: 181 PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAG 240
           PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAG
Sbjct: 181 PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAG 240

Query: 241 VVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKP 275
           VVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKP
Sbjct: 241 VVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKP 275


>gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]
          Length = 275

 Score =  581 bits (1498), Expect = e-166
 Identities = 272/275 (98%), Positives = 272/275 (98%)

Query: 1   MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCG 60
           MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRV   YWMHFCG
Sbjct: 1   MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCG 60

Query: 61  GSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGA 120
           GSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGA
Sbjct: 61  GSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGA 120

Query: 121 DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV 180
           DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV
Sbjct: 121 DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV 180

Query: 181 PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAG 240
           PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAG
Sbjct: 181 PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAG 240

Query: 241 VVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKP 275
           VVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKP
Sbjct: 241 VVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKP 275


>gi|11321636 tryptase delta 1 [Homo sapiens]
          Length = 242

 Score =  432 bits (1112), Expect = e-121
 Identities = 199/235 (84%), Positives = 216/235 (91%)

Query: 1   MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCG 60
           ML+LLLLALPVLAS AY APAPGQALQ+ GIVGGQEAPRSKWPWQVSLRVR  YWMHFCG
Sbjct: 8   MLSLLLLALPVLASPAYVAPAPGQALQQTGIVGGQEAPRSKWPWQVSLRVRGPYWMHFCG 67

Query: 61  GSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGA 120
           GSLIHPQWVLTAAHCV PD+KDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFY  Q GA
Sbjct: 68  GSLIHPQWVLTAAHCVEPDIKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYIIQTGA 127

Query: 121 DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV 180
           DIALLELEEPVN+SSH+HTVTLPPASETFPPGMPCWVTGWGDVDN+  LPPP+PLK+V+V
Sbjct: 128 DIALLELEEPVNISSHIHTVTLPPASETFPPGMPCWVTGWGDVDNNVHLPPPYPLKEVEV 187

Query: 181 PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGT 235
           P++ENH+C+A+YH G +TG   +IVRDDMLCAG+   DSCQGDSGGPLVCKVNGT
Sbjct: 188 PVVENHLCNAEYHTGLHTGHSFQIVRDDMLCAGSENHDSCQGDSGGPLVCKVNGT 242


>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
          Length = 321

 Score =  235 bits (599), Expect = 4e-62
 Identities = 127/272 (46%), Positives = 164/272 (60%), Gaps = 15/272 (5%)

Query: 4   LLLLALPVLASRAYAAPAPGQALQRVG--IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGG 61
           LLLLA+P ++ R          +   G  IVGG  AP   WPWQ SLR+R    +H CGG
Sbjct: 9   LLLLAVPGVSLRTLQPGCGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRR---VHVCGG 65

Query: 62  SLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGA- 120
           SL+ PQWVLTAAHC    +   +  +V L E  +        V +II+H    + Q G  
Sbjct: 66  SLLSPQWVLTAAHCFSGSLNS-SDYQVHLGELEITLSPHFSTVRQIILHSS-PSGQPGTS 123

Query: 121 -DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVK 179
            DIAL+EL  PV +SS +  V LP AS+ F PG+ CWVTGWG     E LPPP+ L++VK
Sbjct: 124 GDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLREVK 183

Query: 180 VPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQA 239
           V +++   C   Y      G    I++ DMLCA     D+CQ DSGGPLVC+VNG W+QA
Sbjct: 184 VSVVDTETCRRDY-----PGPGGSILQPDMLCARGPG-DACQDDSGGPLVCQVNGAWVQA 237

Query: 240 GVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYV 271
           G+VSWGEGC +PNRPG+YTRV  Y++WI  ++
Sbjct: 238 GIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHI 269


>gi|13994276 marapsin [Homo sapiens]
          Length = 290

 Score =  226 bits (576), Expect = 2e-59
 Identities = 120/274 (43%), Positives = 165/274 (60%), Gaps = 9/274 (3%)

Query: 5   LLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLI 64
           LLL L   + RA AA A G+      +VGGQ+    +WPWQVS++   R   HFCGGSLI
Sbjct: 9   LLLLLCFGSQRAKAATACGRPRMLNRMVGGQDTQEGEWPWQVSIQ---RNGSHFCGGSLI 65

Query: 65  HPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQD---QLLPVSRIIVHPQFYTAQIGAD 121
             QWVLTAAHC   +  + +  +V L  + L           V ++  +P +      AD
Sbjct: 66  AEQWVLTAAHCFR-NTSETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSAD 124

Query: 122 IALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVP 181
           +AL+ELE PV  ++++  V LP  S  F  GM CWVTGWG    ++ LP P  L+++ VP
Sbjct: 125 VALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVP 184

Query: 182 IMENHICDAKYHLGAYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQA 239
           I++   C+  Y      G   + +++DMLCAG    ++D+C+GDSGGPLVC V  +WLQA
Sbjct: 185 IIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQA 244

Query: 240 GVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPK 273
           GV+SWGEGCA+ NRPG+Y RVT + +WIH  +PK
Sbjct: 245 GVISWGEGCARQNRPGVYIRVTAHHNWIHRIIPK 278


>gi|117956391 protease, serine, 33 [Homo sapiens]
          Length = 280

 Score =  216 bits (550), Expect = 2e-56
 Identities = 120/269 (44%), Positives = 153/269 (56%), Gaps = 9/269 (3%)

Query: 4   LLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSL 63
           LLLL L    ++   + A GQ      IVGG++    +WPWQ S++ R     H CGGSL
Sbjct: 10  LLLLVLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGA---HVCGGSL 66

Query: 64  IHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQL---LPVSRIIVHPQFYTAQIGA 120
           I PQWVLTAAHC  P     A  RV+L    L         +PV R+++ P +       
Sbjct: 67  IAPQWVLTAAHCF-PRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARG 125

Query: 121 DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV 180
           D+ALL+L  PV +S+ V  V LP      PPG PC VTGWG +     LP   PL+ V+V
Sbjct: 126 DLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRV 185

Query: 181 PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQ 238
           P++++  CD  YH+GA      RIV    LCAG     +D+CQGDSGGPL C  +G+W+ 
Sbjct: 186 PLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVL 245

Query: 239 AGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267
            GVVSWG+GCA PNRPG+YT V  Y  WI
Sbjct: 246 VGVVSWGKGCALPNRPGVYTSVATYSPWI 274


>gi|4506153 prostasin preproprotein [Homo sapiens]
          Length = 343

 Score =  202 bits (513), Expect = 3e-52
 Identities = 110/273 (40%), Positives = 150/273 (54%), Gaps = 10/273 (3%)

Query: 4   LLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSL 63
           LL L L    + A  A AP     +  I GG  A   +WPWQVS+       +H CGGSL
Sbjct: 18  LLYLGLLRSGTGAEGAEAPCGVAPQARITGGSSAVAGQWPWQVSITYEG---VHVCGGSL 74

Query: 64  IHPQWVLTAAHCVGPDVKDLAALRVQLREQHL--YYQD-QLLPVSRIIVHPQFYTAQIGA 120
           +  QWVL+AAHC  P      A  V+L    L  Y +D ++  +  II HP +       
Sbjct: 75  VSEQWVLSAAHCF-PSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQG 133

Query: 121 DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV 180
           DIALL+L  P+  S ++  + LP A+ +FP G+ C VTGWG V     L  P PL+Q++V
Sbjct: 134 DIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEV 193

Query: 181 PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQ 238
           P++    C+  Y++ A   ++   V++DM+CAG     +D+CQGDSGGPL C V G W  
Sbjct: 194 PLISRETCNCLYNIDA-KPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYL 252

Query: 239 AGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYV 271
            G+VSWG+ C   NRPG+YT  + Y  WI   V
Sbjct: 253 TGIVSWGDACGARNRPGVYTLASSYASWIQSKV 285


>gi|11545839 protease, serine, 22 [Homo sapiens]
          Length = 317

 Score =  199 bits (506), Expect = 2e-51
 Identities = 109/277 (39%), Positives = 160/277 (57%), Gaps = 15/277 (5%)

Query: 3   NLLLLALPVL--ASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCG 60
           +LLLLA   +  A+R    PA G+  Q   +VGG+++  S+WPW VS++   +   H C 
Sbjct: 20  SLLLLASTAILNAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQ---KNGTHHCA 76

Query: 61  GSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYY---QDQLLPVSRIIVHPQF-YTA 116
           GSL+  +WV+TAAHC   ++       V L    L     + Q + V+ +  HP + +  
Sbjct: 77  GSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQKVGVAWVEPHPVYSWKE 136

Query: 117 QIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLK 176
              ADIAL+ LE  +  S  V  + LP AS   PP   CW++GWG + +   LP P  L+
Sbjct: 137 GACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGVPLPHPQTLQ 196

Query: 177 QVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNG 234
           ++KVPI+++ +C   Y  GA  G     + +DMLCAG     RD+C GDSGGPL+C+V+G
Sbjct: 197 KLKVPIIDSEVCSHLYWRGAGQGP----ITEDMLCAGYLEGERDACLGDSGGPLMCQVDG 252

Query: 235 TWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYV 271
            WL AG++SWGEGCA+ NRPG+Y  ++ +  W+   V
Sbjct: 253 AWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIV 289


>gi|21614531 testisin isoform 2 [Homo sapiens]
          Length = 312

 Score =  198 bits (504), Expect = 4e-51
 Identities = 108/264 (40%), Positives = 149/264 (56%), Gaps = 24/264 (9%)

Query: 18  AAPAPGQALQRV---GIVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAH 74
           AAP  G   +RV    IVGG++A   +WPWQ SLR+ D    H CG SL+  +W LTAAH
Sbjct: 26  AAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDS---HVCGVSLLSHRWALTAAH 82

Query: 75  CVGPDVKDLAALRVQLREQ---------HLYYQDQLLPVSRIIVHPQFYTAQIGADIALL 125
           C   D+ D +   VQ  +            YY      VS I + P+ Y      DIAL+
Sbjct: 83  CFETDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYF--VSNIYLSPR-YLGNSPYDIALV 139

Query: 126 ELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMEN 185
           +L  PV  + H+  + L  ++  F     CWVTGWG +  DE LP P  L++V+V I+ N
Sbjct: 140 KLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINN 199

Query: 186 HICDAKYHLGAYTGDDVRIVRDDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVS 243
            +C+  +   ++  D    +  DM+CAGN +  +D+C GDSGGPL C  NG W Q GVVS
Sbjct: 200 SMCNHLFLKYSFRKD----IFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVS 255

Query: 244 WGEGCAQPNRPGIYTRVTYYLDWI 267
           WG GC +PNRPG+YT ++++ +WI
Sbjct: 256 WGVGCGRPNRPGVYTNISHHFEWI 279


>gi|5803197 testisin isoform 1 [Homo sapiens]
          Length = 314

 Score =  193 bits (491), Expect = 1e-49
 Identities = 108/266 (40%), Positives = 149/266 (56%), Gaps = 26/266 (9%)

Query: 18  AAPAPGQALQRV---GIVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAH 74
           AAP  G   +RV    IVGG++A   +WPWQ SLR+ D    H CG SL+  +W LTAAH
Sbjct: 26  AAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDS---HVCGVSLLSHRWALTAAH 82

Query: 75  CVGP--DVKDLAALRVQLREQ---------HLYYQDQLLPVSRIIVHPQFYTAQIGADIA 123
           C     D+ D +   VQ  +            YY      VS I + P+ Y      DIA
Sbjct: 83  CFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYF--VSNIYLSPR-YLGNSPYDIA 139

Query: 124 LLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIM 183
           L++L  PV  + H+  + L  ++  F     CWVTGWG +  DE LP P  L++V+V I+
Sbjct: 140 LVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAII 199

Query: 184 ENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGV 241
            N +C+  +   ++  D    +  DM+CAGN +  +D+C GDSGGPL C  NG W Q GV
Sbjct: 200 NNSMCNHLFLKYSFRKD----IFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGV 255

Query: 242 VSWGEGCAQPNRPGIYTRVTYYLDWI 267
           VSWG GC +PNRPG+YT ++++ +WI
Sbjct: 256 VSWGVGCGRPNRPGVYTNISHHFEWI 281


>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
          Length = 567

 Score =  184 bits (468), Expect = 6e-47
 Identities = 100/241 (41%), Positives = 137/241 (56%), Gaps = 14/241 (5%)

Query: 31  IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCVGPD-VKDLAALRVQ 89
           IVGG  A  SKWPWQVSL        H CGG+LI  QWVLTAAHC      K L   +V 
Sbjct: 326 IVGGALASDSKWPWQVSLHFGTT---HICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVY 382

Query: 90  LREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETF 149
               +L+   +   ++ II++  +   +   DIAL+ L +P+ +S+H+H   LP   +TF
Sbjct: 383 AGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTF 442

Query: 150 PPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDM 209
                CW+TG+G     +    PF L++V+V +++   C+      +Y       +   M
Sbjct: 443 SLNETCWITGFGKTRETDDKTSPF-LREVQVNLIDFKKCNDYLVYDSY-------LTPRM 494

Query: 210 LCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267
           +CAG+ R  RDSCQGDSGGPLVC+ N  W  AGV SWG GC Q N+PG+YT+VT  L WI
Sbjct: 495 MCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWI 554

Query: 268 H 268
           +
Sbjct: 555 Y 555


>gi|58218970 protease, serine, 36 [Homo sapiens]
          Length = 855

 Score =  182 bits (462), Expect = 3e-46
 Identities = 106/251 (42%), Positives = 137/251 (54%), Gaps = 17/251 (6%)

Query: 31  IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHC--VGPDVKDLAALRV 88
           IVGG  A    WPWQVSL        H CGGSLI P WVL+AAHC      ++  A   V
Sbjct: 47  IVGGSNAQPGTWPWQVSLHHGGG---HICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSV 103

Query: 89  QLREQHLYYQDQLLP------VSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTL 142
            L    ++ QD  L       V+ I+V   +   ++GAD+ALL L  P ++   V  V L
Sbjct: 104 LLG---VHSQDGPLDGAHTRAVAAIVVPANYSQVELGADLALLRLASPASLGPAVWPVCL 160

Query: 143 PPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDV 202
           P AS  F  G  CW TGWGDV   + LP P+ L++V++ ++    C   Y         +
Sbjct: 161 PRASHRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEATCQCLYSQPGPFNLTL 220

Query: 203 RIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRV 260
           +I+   MLCAG    RRD+CQGDSGGPLVC+  G W QAG+ S+G GC + NRPG++T V
Sbjct: 221 QIL-PGMLCAGYPEGRRDTCQGDSGGPLVCEEGGRWFQAGITSFGFGCGRRNRPGVFTAV 279

Query: 261 TYYLDWIHHYV 271
             Y  WI   V
Sbjct: 280 ATYEAWIREQV 290



 Score = 75.1 bits (183), Expect = 6e-14
 Identities = 66/241 (27%), Positives = 101/241 (41%), Gaps = 22/241 (9%)

Query: 36  EAPR-SKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHC-VGPDVKDLAALRVQLREQ 93
           +APR   WPW+  + V        C G+L+   WVL  A C + P+  D     +     
Sbjct: 327 KAPRPGAWPWEAQVMVPGS---RPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRV 383

Query: 94  HLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGM 153
            L  + +   V+R++ H    +    +D+ALL+L  PVN+S+    V LP     F PG 
Sbjct: 384 LLPSRPRAERVARLVQHENA-SWDNASDLALLQLRTPVNLSAASRPVCLPHPEHYFLPGS 442

Query: 154 PCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD--DMLC 211
            C +  WG  +     P   P   ++  ++    C   Y      G  V +  D    LC
Sbjct: 443 RCRLARWGRGE-----PALGPGALLEAELLGGWWCHCLY---GRQGAAVPLPGDPPHALC 494

Query: 212 AGNTRRD---SCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIH 268
                ++   SC  DS   L+C+  GTW  AG+  +  GC    RP  +  +  +  WI 
Sbjct: 495 PAYQEKEEVGSCWNDSRWSLLCQEEGTWFLAGIRDFPSGCL---RPRAFFPLQTHGPWIS 551

Query: 269 H 269
           H
Sbjct: 552 H 552



 Score = 71.2 bits (173), Expect = 9e-13
 Identities = 64/212 (30%), Positives = 88/212 (41%), Gaps = 32/212 (15%)

Query: 42  WPWQVSLRVR-DRYWMHFCGGSLIHPQWVLTAAHCV-GPDVKDLAALRVQLREQHLYYQD 99
           WPW   + V  DR     C G L+ P WVL A HCV  P    +  + V L         
Sbjct: 601 WPWLAEVHVAGDRV----CTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAGASSLP 656

Query: 100 QLLPVSRIIVH---PQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCW 156
           Q   VSR+++    PQ     +   +ALLEL   V  S     + L PA    PPG  CW
Sbjct: 657 QGHQVSRLVISIRLPQH--LGLRPPLALLELSSRVEPSPSALPICLHPAG--IPPGASCW 712

Query: 157 VTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCA--GN 214
           V GW   +  +R+P         V I+   ICD  Y           I+    LC     
Sbjct: 713 VLGW--KEPQDRVP-----VAAAVSILTQRICDCLYQ---------GILPPGTLCVLYAE 756

Query: 215 TRRDSCQGDSGGPLVCKV-NGTWLQAGVVSWG 245
            + + C+  S  PL+C++  G+W+  G+   G
Sbjct: 757 GQENRCEMTSAPPLLCQMTEGSWILVGMAVQG 788


>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
          Length = 457

 Score =  180 bits (457), Expect = 1e-45
 Identities = 101/243 (41%), Positives = 131/243 (53%), Gaps = 16/243 (6%)

Query: 31  IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCVGP-DVKDLAALRVQ 89
           IVGGQ     +WPWQ S+ +  R   H CGGS++ P+WV+TAAHC+    +  L++ RV 
Sbjct: 218 IVGGQSVAPGRWPWQASVALGFR---HTCGGSVLAPRWVVTAAHCMHSFRLARLSSWRVH 274

Query: 90  --LREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147
             L         Q   V RII HP +       D+ALL L+  +N S  V  V LP   +
Sbjct: 275 AGLVSHSAVRPHQGALVERIIPHPLYSAQNHDYDVALLRLQTALNFSDTVGAVCLPAKEQ 334

Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207
            FP G  CWV+GWG             L+   VP+    +C++      Y+G     +  
Sbjct: 335 HFPKGSRCWVSGWGHTHPSHTYSSDM-LQDTVVPLFSTQLCNSSC---VYSG----ALTP 386

Query: 208 DMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265
            MLCAG  + R D+CQGDSGGPLVC    TW   GVVSWG GCA+PN PG+Y +V  +LD
Sbjct: 387 RMLCAGYLDGRADACQGDSGGPLVCPDGDTWRLVGVVSWGRGCAEPNHPGVYAKVAEFLD 446

Query: 266 WIH 268
           WIH
Sbjct: 447 WIH 449


>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
           sapiens]
          Length = 454

 Score =  179 bits (455), Expect = 2e-45
 Identities = 101/248 (40%), Positives = 139/248 (56%), Gaps = 19/248 (7%)

Query: 31  IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90
           IVGG  +  S+WPWQ SL+ +     H CGGS+I P W++TAAHCV  D+    +  +Q+
Sbjct: 217 IVGGNMSLLSQWPWQASLQFQG---YHLCGGSVITPLWIITAAHCVY-DLYLPKSWTIQV 272

Query: 91  REQHLYYQDQLLP---VSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147
               L   D   P   V +I+ H ++   ++G DIAL++L  P+  +  +  V LP + E
Sbjct: 273 GLVSLL--DNPAPSHLVEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPVCLPNSEE 330

Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207
            FP G  CW +GWG  ++      P  L    VP++ N IC+   H   Y G    I+  
Sbjct: 331 NFPDGKVCWTSGWGATEDGAGDASPV-LNHAAVPLISNKICN---HRDVYGG----IISP 382

Query: 208 DMLCAGNTRR--DSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265
            MLCAG      DSCQGDSGGPLVC+    W   G  S+G GCA+ N+PG+YTRVT +LD
Sbjct: 383 SMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLD 442

Query: 266 WIHHYVPK 273
           WIH  + +
Sbjct: 443 WIHEQMER 450


>gi|4503627 coagulation factor XI precursor [Homo sapiens]
          Length = 625

 Score =  179 bits (454), Expect = 2e-45
 Identities = 98/242 (40%), Positives = 129/242 (53%), Gaps = 16/242 (6%)

Query: 31  IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ- 89
           IVGG  + R +WPWQV+L        H CGGS+I  QW+LTAAHC    V+    LRV  
Sbjct: 388 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFY-GVESPKILRVYS 446

Query: 90  --LREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147
             L +  +        V  II+H Q+  A+ G DIALL+LE  VN +     + LP   +
Sbjct: 447 GILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGD 506

Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207
                  CWVTGWG     +++     L++ K+P++ N  C  +Y     T         
Sbjct: 507 RNVIYTDCWVTGWGYRKLRDKIQNT--LQKAKIPLVTNEECQKRYRGHKIT--------H 556

Query: 208 DMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 265
            M+CAG     +D+C+GDSGGPL CK N  W   G+ SWGEGCAQ  RPG+YT V  Y+D
Sbjct: 557 KMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVD 616

Query: 266 WI 267
           WI
Sbjct: 617 WI 618


>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
          Length = 811

 Score =  178 bits (451), Expect = 5e-45
 Identities = 101/248 (40%), Positives = 137/248 (55%), Gaps = 21/248 (8%)

Query: 31  IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRV-- 88
           IVGG  +   +WPWQ SL+VR R   H CGG+LI  +WV+TAAHC   D      L    
Sbjct: 577 IVGGAVSSEGEWPWQASLQVRGR---HICGGALIADRWVITAAHCFQEDSMASTVLWTVF 633

Query: 89  --QLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPAS 146
             ++ +   +  +    VSR+++HP         D+ALL+L+ PV  S+ V  V LP  S
Sbjct: 634 LGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARS 693

Query: 147 ETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 206
             F PG+ CW+TGWG +   E  P    L++V V ++   +C   Y            V 
Sbjct: 694 HFFEPGLHCWITGWGAL--REGGPISNALQKVDVQLIPQDLCSEVYRYQ---------VT 742

Query: 207 DDMLCAG--NTRRDSCQGDSGGPLVCK-VNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYY 263
             MLCAG    ++D+CQGDSGGPLVCK ++G W  AG+VSWG GC +PN  G+YTR+T  
Sbjct: 743 PRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGV 802

Query: 264 LDWIHHYV 271
           + WI   V
Sbjct: 803 ISWIQQVV 810


>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
          Length = 638

 Score =  177 bits (448), Expect = 1e-44
 Identities = 96/241 (39%), Positives = 138/241 (57%), Gaps = 14/241 (5%)

Query: 31  IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCV-GPDVKDLAALRVQ 89
           IVGG  +   +WPWQVSL+V+     H CGGSLI  QWVLTAAHC  G  ++D+  +   
Sbjct: 391 IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 450

Query: 90  LREQHLYYQDQ-LLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASET 148
           +       +D     +  II+H  +  ++   DIAL++L+ P+N +     + LP   +T
Sbjct: 451 ILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDT 510

Query: 149 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 208
                 CWVTGWG   + E+      L++V +P++ N  C  +Y        D +I +  
Sbjct: 511 STIYTNCWVTGWGF--SKEKGEIQNILQKVNIPLVTNEECQKRYQ-------DYKITQR- 560

Query: 209 MLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDW 266
           M+CAG     +D+C+GDSGGPLVCK NG W   G+ SWGEGCA+  +PG+YT+V  Y+DW
Sbjct: 561 MVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDW 620

Query: 267 I 267
           I
Sbjct: 621 I 621


>gi|148806900 epidermis-specific serine protease-like protein [Homo
           sapiens]
          Length = 328

 Score =  176 bits (447), Expect = 2e-44
 Identities = 96/256 (37%), Positives = 146/256 (57%), Gaps = 22/256 (8%)

Query: 23  GQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCVGPDVKD 82
           GQ +    +VGGQ+A   +WPWQVSL     +    CGGSL+  + +LTAAHC+ P    
Sbjct: 20  GQPVYSSRVVGGQDAAAGRWPWQVSLHFDHNF---ICGGSLVSERLILTAAHCIQPTWTT 76

Query: 83  ------LAALRV-QLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSS 135
                 L ++ V   R++  YY      VS+I++HP++      AD+ALL+L   V  +S
Sbjct: 77  FSYTVWLGSITVGDSRKRVKYY------VSKIVIHPKYQDTT--ADVALLKLSSQVTFTS 128

Query: 136 HVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYH-L 194
            +  + LP  ++       CWVTGWG V           L++ +VPI++   C+  Y+ +
Sbjct: 129 AILPICLPSVTKQLAIPPFCWVTGWGKVKESSDRDYHSALQEAEVPIIDRQACEQLYNPI 188

Query: 195 GAYTGDDVRIVRDDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPN 252
           G +      ++++D +CAG+T+  +DSC+GDSGGPL C ++G W+Q GVVSWG  C + +
Sbjct: 189 GIFLPALEPVIKEDKICAGDTQNMKDSCKGDSGGPLSCHIDGVWIQTGVVSWGLECGK-S 247

Query: 253 RPGIYTRVTYYLDWIH 268
            PG+YT V YY  WI+
Sbjct: 248 LPGVYTNVIYYQKWIN 263


>gi|21614533 testisin isoform 3 [Homo sapiens]
          Length = 300

 Score =  173 bits (439), Expect = 1e-43
 Identities = 102/264 (38%), Positives = 139/264 (52%), Gaps = 36/264 (13%)

Query: 18  AAPAPGQALQRV---GIVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAH 74
           AAP  G   +RV    IVGG++A   +WPWQ SLR+ D    H CG SL+  +W LTAAH
Sbjct: 26  AAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDS---HVCGVSLLSHRWALTAAH 82

Query: 75  CVGP--DVKDLAALRVQLREQ---------HLYYQDQLLPVSRIIVHPQFYTAQIGADIA 123
           C     D+ D +   VQ  +            YY      VS I + P+ Y      DIA
Sbjct: 83  CFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYF--VSNIYLSPR-YLGNSPYDIA 139

Query: 124 LLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIM 183
           L++L  PV  + H+  + L  ++  F     CWVTGWG +  DE LP P  L++V+V I+
Sbjct: 140 LVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAII 199

Query: 184 ENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVS 243
            N +C+  +   ++  D    +  DM            GDSGGPL C  NG W Q GVVS
Sbjct: 200 NNSMCNHLFLKYSFRKD----IFGDM------------GDSGGPLACNKNGLWYQIGVVS 243

Query: 244 WGEGCAQPNRPGIYTRVTYYLDWI 267
           WG GC +PNRPG+YT ++++ +WI
Sbjct: 244 WGVGCGRPNRPGVYTNISHHFEWI 267


>gi|205360905 testis-specific serine protease 1 [Homo sapiens]
          Length = 318

 Score =  171 bits (434), Expect = 5e-43
 Identities = 94/246 (38%), Positives = 133/246 (54%), Gaps = 17/246 (6%)

Query: 31  IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCVGPD------VKDLA 84
           + GG E+ R +WPWQ SLR+R R   H CGGSL+  +WVL+AAHC             L 
Sbjct: 55  VAGGVESARGRWPWQASLRLRRR---HRCGGSLLSRRWVLSAAHCFQKHYYPSEWTVQLG 111

Query: 85  ALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPP 144
            L  +    +L        V  IIV+P      +  DIALL L   V  ++++  + +  
Sbjct: 112 ELTSRPTPWNLRAYSSRYKVQDIIVNPDALGV-LRNDIALLRLASSVTYNAYIQPICIES 170

Query: 145 ASETFPPGMPCWVTGWGDVD-NDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVR 203
           ++  F     CWVTGWG +  +   LPPP+ L++ +V I+ N  C+  +   +       
Sbjct: 171 STFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQPSSRS---- 226

Query: 204 IVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVT 261
           ++ D M CAG  +   D+C+GDSGGPLVC  +G W Q G+VSWG  C QPNRPG+YT ++
Sbjct: 227 MIWDSMFCAGAEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTNIS 286

Query: 262 YYLDWI 267
            Y  WI
Sbjct: 287 VYFHWI 292


>gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
          Length = 418

 Score =  171 bits (434), Expect = 5e-43
 Identities = 99/243 (40%), Positives = 136/243 (55%), Gaps = 23/243 (9%)

Query: 31  IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCVGPDVKD---LAALR 87
           I+GG EA    WPWQVSLR+ +    H CGGSLI+  W+LTAAHC   +      +A   
Sbjct: 187 ILGGTEAEEGSWPWQVSLRLNNA---HHCGGSLINNMWILTAAHCFRSNSNPRDWIATSG 243

Query: 88  VQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASE 147
           +      L  +     V  I++H  + +A    DIAL+ LE  V  +  +H+V LP A++
Sbjct: 244 ISTTFPKLRMR-----VRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQ 298

Query: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207
             PPG   +VTGWG  +      P   L+Q +V I+ N +C+A +   +Y G     +  
Sbjct: 299 NIPPGSTAYVTGWGAQEYAGHTVP--ELRQGQVRIISNDVCNAPH---SYNG----AILS 349

Query: 208 DMLCAGNTRR--DSCQGDSGGPLVCK-VNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264
            MLCAG  +   D+CQGDSGGPLV +     W   G+VSWG+ C  P++PG+YTRVT YL
Sbjct: 350 GMLCAGVPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYL 409

Query: 265 DWI 267
           DWI
Sbjct: 410 DWI 412


>gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens]
          Length = 410

 Score =  171 bits (433), Expect = 6e-43
 Identities = 97/243 (39%), Positives = 132/243 (54%), Gaps = 18/243 (7%)

Query: 31  IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCVGPDV-----KDLAA 85
           ++GG  AP  KWPWQVSL+  +   +H CGGSLI  +WVLTAAHCV         + L A
Sbjct: 163 MIGGLPAPNKKWPWQVSLQTSN---IHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLA 219

Query: 86  LRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPA 145
              +  +   + +D + P +       F  A + +DIAL  L   VN SSH+    LP  
Sbjct: 220 GIGRWDQAWKHLEDIIFPSN-------FDFATLTSDIALALLAYSVNYSSHIQPACLPEK 272

Query: 146 SETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIV 205
                 G  CWVTGWG V      P P  L++ ++ IM +  C     L        ++V
Sbjct: 273 LFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEM--LKNKNISKSKMV 330

Query: 206 RDDMLCAGNTR-RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264
               +C  N + +D+CQGDSGGPLVC++NGTW+Q G+VSWG GC +   PG+YT V++Y 
Sbjct: 331 TRGTVCGYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYK 390

Query: 265 DWI 267
            WI
Sbjct: 391 KWI 393


>gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo
           sapiens]
          Length = 410

 Score =  171 bits (433), Expect = 6e-43
 Identities = 97/243 (39%), Positives = 132/243 (54%), Gaps = 18/243 (7%)

Query: 31  IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCVGPDV-----KDLAA 85
           ++GG  AP  KWPWQVSL+  +   +H CGGSLI  +WVLTAAHCV         + L A
Sbjct: 163 MIGGLPAPNKKWPWQVSLQTSN---IHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLA 219

Query: 86  LRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPA 145
              +  +   + +D + P +       F  A + +DIAL  L   VN SSH+    LP  
Sbjct: 220 GIGRWDQAWKHLEDIIFPSN-------FDFATLTSDIALALLAYSVNYSSHIQPACLPEK 272

Query: 146 SETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIV 205
                 G  CWVTGWG V      P P  L++ ++ IM +  C     L        ++V
Sbjct: 273 LFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEM--LKNKNISKSKMV 330

Query: 206 RDDMLCAGNTR-RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264
               +C  N + +D+CQGDSGGPLVC++NGTW+Q G+VSWG GC +   PG+YT V++Y 
Sbjct: 331 TRGTVCGYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYK 390

Query: 265 DWI 267
            WI
Sbjct: 391 KWI 393


>gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo
           sapiens]
          Length = 410

 Score =  171 bits (433), Expect = 6e-43
 Identities = 97/243 (39%), Positives = 132/243 (54%), Gaps = 18/243 (7%)

Query: 31  IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCVGPDV-----KDLAA 85
           ++GG  AP  KWPWQVSL+  +   +H CGGSLI  +WVLTAAHCV         + L A
Sbjct: 163 MIGGLPAPNKKWPWQVSLQTSN---IHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLA 219

Query: 86  LRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPA 145
              +  +   + +D + P +       F  A + +DIAL  L   VN SSH+    LP  
Sbjct: 220 GIGRWDQAWKHLEDIIFPSN-------FDFATLTSDIALALLAYSVNYSSHIQPACLPEK 272

Query: 146 SETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIV 205
                 G  CWVTGWG V      P P  L++ ++ IM +  C     L        ++V
Sbjct: 273 LFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEM--LKNKNISKSKMV 330

Query: 206 RDDMLCAGNTR-RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264
               +C  N + +D+CQGDSGGPLVC++NGTW+Q G+VSWG GC +   PG+YT V++Y 
Sbjct: 331 TRGTVCGYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYK 390

Query: 265 DWI 267
            WI
Sbjct: 391 KWI 393


>gi|110815798 ovochymase 1 [Homo sapiens]
          Length = 1134

 Score =  171 bits (433), Expect = 6e-43
 Identities = 99/247 (40%), Positives = 139/247 (56%), Gaps = 24/247 (9%)

Query: 31  IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRV-- 88
           I GG+EA    WPWQV LR    Y    CGG++I+P W+LTAAHCV      L+   +  
Sbjct: 575 IAGGEEACPHCWPWQVGLRFLGDYQ---CGGAIINPVWILTAAHCVQLKNNPLSWTIIAG 631

Query: 89  ----QLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPP 144
                L+E      +Q+     IIVH  F T    +DIAL++L  P+  +S V  V LP 
Sbjct: 632 DHDRNLKES----TEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSVVRPVCLPH 687

Query: 145 ASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI 204
           ++E       C VTGWG +  D  L     L+Q++V ++E  +C+  Y+  A+ G     
Sbjct: 688 SAEPLFSSEICAVTGWGSISADGGLAS--RLQQIQVHVLEREVCEHTYY-SAHPGG---- 740

Query: 205 VRDDMLCAG---NTRRDSCQGDSGGPLVCK-VNGTWLQAGVVSWGEGCAQPNRPGIYTRV 260
           + + M+CAG   +  +D CQGDSGGPLVC+  NG ++  G+VSWG GC QP +PG++ RV
Sbjct: 741 ITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVFARV 800

Query: 261 TYYLDWI 267
             +LDWI
Sbjct: 801 MIFLDWI 807



 Score =  136 bits (343), Expect = 2e-32
 Identities = 87/243 (35%), Positives = 132/243 (54%), Gaps = 28/243 (11%)

Query: 43  PWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCVGP-DVKDLAALRVQLREQHLYYQD-- 99
           PWQVSL+  +    HFCGGSLI    V+TAAHC+     K L  + V   E  L+ +D  
Sbjct: 59  PWQVSLKSDEH---HFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQ 115

Query: 100 -QLLPVSRIIVHPQFYTAQ-IGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWV 157
            Q +PVS+II HP++ + + +  DIALL L+  V   + V  + LP + +   PG+ C  
Sbjct: 116 EQNIPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILCLS 175

Query: 158 TGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAG--NT 215
           +GWG +           L+++++PIM++  C+           ++  +   MLCAG  + 
Sbjct: 176 SGWGKISKTSEYSN--VLQEMELPIMDDRACNT-----VLKSMNLPPLGRTMLCAGFPDW 228

Query: 216 RRDSCQGDSGGPLVC-KVNGTWLQAGVVSWGEGCAQPNRP----------GIYTRVTYYL 264
             D+CQGDSGGPLVC +  G W+ AG+ SW  GCA  + P          GI+++V+  +
Sbjct: 229 GMDACQGDSGGPLVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKASLGIFSKVSELM 288

Query: 265 DWI 267
           D+I
Sbjct: 289 DFI 291


>gi|15559207 elastase 2A preproprotein [Homo sapiens]
          Length = 269

 Score =  169 bits (429), Expect = 2e-42
 Identities = 105/281 (37%), Positives = 152/281 (54%), Gaps = 25/281 (8%)

Query: 1   MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVRDR-YWMHFC 59
           M+  LLL+  V  + +   P     + RV  VGG+EA  + WPWQVSL+      W H C
Sbjct: 1   MIRTLLLSTLVAGALSCGDPTYPPYVTRV--VGGEEARPNSWPWQVSLQYSSNGKWYHTC 58

Query: 60  GGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQ---LLPVSRIIVHPQFYTA 116
           GGSLI   WVLTAAHC+          RV L   +LY  +     + VS+I+VH  + + 
Sbjct: 59  GGSLIANSWVLTAAHCISSS----RTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSN 114

Query: 117 QI--GADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFP 174
           QI  G DIALL+L  PV+++  +    LPPA    P   PC+VTGWG +  +  +P    
Sbjct: 115 QISKGNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPD--V 172

Query: 175 LKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTR-RDSCQGDSGGPLVCKV- 232
           L+Q ++ +++   C +    G+        V+  M+CAG      SC GDSGGPL C+  
Sbjct: 173 LQQGRLLVVDYATCSSSAWWGS-------SVKTSMICAGGDGVISSCNGDSGGPLNCQAS 225

Query: 233 NGTWLQAGVVSWGE--GCAQPNRPGIYTRVTYYLDWIHHYV 271
           +G W   G+VS+G   GC   ++P ++TRV+ Y+DWI+  +
Sbjct: 226 DGRWQVHGIVSFGSRLGCNYYHKPSVFTRVSNYIDWINSVI 266


>gi|118498341 chymotrypsin B1 [Homo sapiens]
          Length = 263

 Score =  169 bits (427), Expect = 3e-42
 Identities = 99/272 (36%), Positives = 136/272 (50%), Gaps = 21/272 (7%)

Query: 1   MLNLLLLALPVLASRAYAAPAPG-----QALQRVGIVGGQEAPRSKWPWQVSLRVRDRYW 55
           M +L LL+   L   A+    P        L R  IV G++A    WPWQVSL+  D+  
Sbjct: 1   MASLWLLSCFSLVGAAFGCGVPAIHPVLSGLSR--IVNGEDAVPGSWPWQVSLQ--DKTG 56

Query: 56  MHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYT 115
            HFCGGSLI   WV+TAAHC G    D+     +  +       Q+L ++++  +P+F  
Sbjct: 57  FHFCGGSLISEDWVVTAAHC-GVRTSDVVVAG-EFDQGSDEENIQVLKIAKVFKNPKFSI 114

Query: 116 AQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPL 175
             +  DI LL+L  P   S  V  V LP A + FP G  C  TGWG    +    P   L
Sbjct: 115 LTVNNDITLLKLATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPD-KL 173

Query: 176 KQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGT 235
           +Q  +P++ N  C   +          R + D M+CAG +   SC GDSGGPLVC+ +G 
Sbjct: 174 QQAALPLLSNAECKKSWG---------RRITDVMICAGASGVSSCMGDSGGPLVCQKDGA 224

Query: 236 WLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267
           W   G+VSWG      + PG+Y RVT  + W+
Sbjct: 225 WTLVGIVSWGSDTCSTSSPGVYARVTKLIPWV 256


>gi|4505881 plasminogen [Homo sapiens]
          Length = 810

 Score =  166 bits (419), Expect = 3e-41
 Identities = 95/241 (39%), Positives = 130/241 (53%), Gaps = 22/241 (9%)

Query: 31  IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCV--GPDVKDLAALRV 88
           +VGG  A    WPWQVSLR R  + MHFCGG+LI P+WVLTAAHC+   P       +  
Sbjct: 581 VVGGCVAHPHSWPWQVSLRTR--FGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILG 638

Query: 89  QLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASET 148
             +E +L    Q + VSR+ + P         DIALL+L  P  ++  V    LP  +  
Sbjct: 639 AHQEVNLEPHVQEIEVSRLFLEPT------RKDIALLKLSSPAVITDKVIPACLPSPNYV 692

Query: 149 FPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDD 208
                 C++TGWG+            LK+ ++P++EN +C+    L          V+  
Sbjct: 693 VADRTECFITGWGETQGTFGAGL---LKEAQLPVIENKVCNRYEFLNGR-------VQST 742

Query: 209 MLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDW 266
            LCAG+     DSCQGDSGGPLVC     ++  GV SWG GCA+PN+PG+Y RV+ ++ W
Sbjct: 743 ELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTW 802

Query: 267 I 267
           I
Sbjct: 803 I 803


>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
           sapiens]
          Length = 529

 Score =  165 bits (417), Expect = 5e-41
 Identities = 94/263 (35%), Positives = 139/263 (52%), Gaps = 18/263 (6%)

Query: 11  VLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVL 70
           V++ R  A      + ++  IVGG+ A    WPWQVSL V++   +H CGGS+I P+W++
Sbjct: 273 VVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQN---VHVCGGSIITPEWIV 329

Query: 71  TAAHCVGPDVKD---LAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLEL 127
           TAAHCV   + +     A    LR+  ++Y      V ++I HP + +     DIAL++L
Sbjct: 330 TAAHCVEKPLNNPWHWTAFAGILRQSFMFYGAGY-QVEKVISHPNYDSKTKNNDIALMKL 388

Query: 128 EEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHI 187
           ++P+  +  V  V LP       P   CW++GWG  +  E+      L   KV ++E   
Sbjct: 389 QKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATE--EKGKTSEVLNAAKVLLIETQR 446

Query: 188 CDAKYHLGAYTGDDVRIVRDDMLCAGNTRR--DSCQGDSGGPLVCKVNGTWLQAGVVSWG 245
           C+++Y           ++   M+CAG  +   DSCQGDSGGPLV   N  W   G  SWG
Sbjct: 447 CNSRYVYD-------NLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWG 499

Query: 246 EGCAQPNRPGIYTRVTYYLDWIH 268
            GCA+  RPG+Y  V  + DWI+
Sbjct: 500 SGCAKAYRPGVYGNVMVFTDWIY 522


>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
           sapiens]
          Length = 492

 Score =  165 bits (417), Expect = 5e-41
 Identities = 94/263 (35%), Positives = 139/263 (52%), Gaps = 18/263 (6%)

Query: 11  VLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVL 70
           V++ R  A      + ++  IVGG+ A    WPWQVSL V++   +H CGGS+I P+W++
Sbjct: 236 VVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQN---VHVCGGSIITPEWIV 292

Query: 71  TAAHCVGPDVKD---LAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLEL 127
           TAAHCV   + +     A    LR+  ++Y      V ++I HP + +     DIAL++L
Sbjct: 293 TAAHCVEKPLNNPWHWTAFAGILRQSFMFYGAGY-QVEKVISHPNYDSKTKNNDIALMKL 351

Query: 128 EEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHI 187
           ++P+  +  V  V LP       P   CW++GWG  +  E+      L   KV ++E   
Sbjct: 352 QKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATE--EKGKTSEVLNAAKVLLIETQR 409

Query: 188 CDAKYHLGAYTGDDVRIVRDDMLCAGNTRR--DSCQGDSGGPLVCKVNGTWLQAGVVSWG 245
           C+++Y           ++   M+CAG  +   DSCQGDSGGPLV   N  W   G  SWG
Sbjct: 410 CNSRYVYD-------NLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWG 462

Query: 246 EGCAQPNRPGIYTRVTYYLDWIH 268
            GCA+  RPG+Y  V  + DWI+
Sbjct: 463 SGCAKAYRPGVYGNVMVFTDWIY 485


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.140    0.469 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,900,637
Number of Sequences: 37866
Number of extensions: 646947
Number of successful extensions: 2053
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 164
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1362
Number of HSP's gapped (non-prelim): 194
length of query: 275
length of database: 18,247,518
effective HSP length: 101
effective length of query: 174
effective length of database: 14,423,052
effective search space: 2509611048
effective search space used: 2509611048
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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