Guide to the Human Genome
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Search of human proteins with 68161500

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|68161500 Wiskott-Aldrich syndrome protein family member 1
[Homo sapiens]
         (559 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho...  1152   0.0  
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho...  1152   0.0  
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho...  1152   0.0  
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom...  1152   0.0  
gi|11386183 WAS protein family, member 2 [Homo sapiens]               452   e-127
gi|13699803 WAS protein family, member 3 [Homo sapiens]               450   e-126
gi|160707881 formin 2 [Homo sapiens]                                  113   4e-25
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...   111   2e-24
gi|47132519 Ras association and pleckstrin homology domains 1 is...   101   2e-21
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    97   4e-20
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     94   3e-19
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     94   3e-19
gi|116284392 mucin 2 precursor [Homo sapiens]                          94   3e-19
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    93   6e-19
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    92   1e-18
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    92   1e-18
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    92   2e-18
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    92   2e-18
gi|150417989 cyclin K isoform 1 [Homo sapiens]                         90   5e-18
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    89   1e-17
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          87   3e-17
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          87   3e-17
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          87   3e-17
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    87   5e-17
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]               87   5e-17
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    86   7e-17
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    86   9e-17
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  84   4e-16
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    83   8e-16
gi|153792074 proline rich 12 [Homo sapiens]                            83   8e-16

>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 1152 bits (2981), Expect = 0.0
 Identities = 559/559 (100%), Positives = 559/559 (100%)

Query: 1   MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAH 60
           MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAH
Sbjct: 1   MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAH 60

Query: 61  SFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIP 120
           SFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIP
Sbjct: 61  SFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIP 120

Query: 121 LQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQK 180
           LQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQK
Sbjct: 121 LQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQK 180

Query: 181 QKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRPQ 240
           QKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRPQ
Sbjct: 181 QKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRPQ 240

Query: 241 TYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSA 300
           TYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSA
Sbjct: 241 TYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSA 300

Query: 301 TGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPA 360
           TGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPA
Sbjct: 301 TGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPA 360

Query: 361 TALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEV 420
           TALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEV
Sbjct: 361 TALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEV 420

Query: 421 QGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIP 480
           QGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIP
Sbjct: 421 QGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIP 480

Query: 481 ASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIA 540
           ASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIA
Sbjct: 481 ASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIA 540

Query: 541 VEYSDSEDDSEFDEVDWLE 559
           VEYSDSEDDSEFDEVDWLE
Sbjct: 541 VEYSDSEDDSEFDEVDWLE 559


>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 1152 bits (2981), Expect = 0.0
 Identities = 559/559 (100%), Positives = 559/559 (100%)

Query: 1   MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAH 60
           MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAH
Sbjct: 1   MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAH 60

Query: 61  SFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIP 120
           SFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIP
Sbjct: 61  SFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIP 120

Query: 121 LQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQK 180
           LQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQK
Sbjct: 121 LQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQK 180

Query: 181 QKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRPQ 240
           QKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRPQ
Sbjct: 181 QKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRPQ 240

Query: 241 TYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSA 300
           TYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSA
Sbjct: 241 TYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSA 300

Query: 301 TGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPA 360
           TGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPA
Sbjct: 301 TGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPA 360

Query: 361 TALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEV 420
           TALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEV
Sbjct: 361 TALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEV 420

Query: 421 QGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIP 480
           QGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIP
Sbjct: 421 QGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIP 480

Query: 481 ASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIA 540
           ASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIA
Sbjct: 481 ASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIA 540

Query: 541 VEYSDSEDDSEFDEVDWLE 559
           VEYSDSEDDSEFDEVDWLE
Sbjct: 541 VEYSDSEDDSEFDEVDWLE 559


>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 1152 bits (2981), Expect = 0.0
 Identities = 559/559 (100%), Positives = 559/559 (100%)

Query: 1   MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAH 60
           MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAH
Sbjct: 1   MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAH 60

Query: 61  SFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIP 120
           SFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIP
Sbjct: 61  SFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIP 120

Query: 121 LQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQK 180
           LQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQK
Sbjct: 121 LQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQK 180

Query: 181 QKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRPQ 240
           QKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRPQ
Sbjct: 181 QKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRPQ 240

Query: 241 TYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSA 300
           TYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSA
Sbjct: 241 TYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSA 300

Query: 301 TGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPA 360
           TGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPA
Sbjct: 301 TGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPA 360

Query: 361 TALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEV 420
           TALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEV
Sbjct: 361 TALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEV 420

Query: 421 QGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIP 480
           QGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIP
Sbjct: 421 QGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIP 480

Query: 481 ASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIA 540
           ASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIA
Sbjct: 481 ASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIA 540

Query: 541 VEYSDSEDDSEFDEVDWLE 559
           VEYSDSEDDSEFDEVDWLE
Sbjct: 541 VEYSDSEDDSEFDEVDWLE 559


>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 1152 bits (2981), Expect = 0.0
 Identities = 559/559 (100%), Positives = 559/559 (100%)

Query: 1   MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAH 60
           MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAH
Sbjct: 1   MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAH 60

Query: 61  SFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIP 120
           SFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIP
Sbjct: 61  SFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIP 120

Query: 121 LQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQK 180
           LQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQK
Sbjct: 121 LQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQK 180

Query: 181 QKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRPQ 240
           QKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRPQ
Sbjct: 181 QKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRPQ 240

Query: 241 TYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSA 300
           TYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSA
Sbjct: 241 TYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSA 300

Query: 301 TGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPA 360
           TGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPA
Sbjct: 301 TGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPA 360

Query: 361 TALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEV 420
           TALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEV
Sbjct: 361 TALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEV 420

Query: 421 QGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIP 480
           QGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIP
Sbjct: 421 QGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIP 480

Query: 481 ASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIA 540
           ASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIA
Sbjct: 481 ASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIA 540

Query: 541 VEYSDSEDDSEFDEVDWLE 559
           VEYSDSEDDSEFDEVDWLE
Sbjct: 541 VEYSDSEDDSEFDEVDWLE 559


>gi|11386183 WAS protein family, member 2 [Homo sapiens]
          Length = 498

 Score =  452 bits (1164), Expect = e-127
 Identities = 280/570 (49%), Positives = 335/570 (58%), Gaps = 87/570 (15%)

Query: 1   MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAH 60
           MPLV RNI+PRHLC   LP  +++ELECVTNI+LAN+IRQL SLSKYAEDIFGELF +A+
Sbjct: 1   MPLVTRNIEPRHLCRQTLP-SVRSELECVTNITLANVIRQLGSLSKYAEDIFGELFTQAN 59

Query: 61  SFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIP 120
           +F+ RV+SL ERVDRL V VTQLDPKEEE+SLQ I  RKAFRSSTIQDQ+LFDR +LP+P
Sbjct: 60  TFASRVSSLAERVDRLQVKVTQLDPKEEEVSLQGINTRKAFRSSTIQDQKLFDRNSLPVP 119

Query: 121 LQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQK 180
           + ETY+ C+ PPPLN LTPYRDDGKE LKFYT+PSYFFDLWKEKMLQDT+D  KEKRK +
Sbjct: 120 VLETYNTCDTPPPLNNLTPYRDDGKEALKFYTDPSYFFDLWKEKMLQDTKDIMKEKRKHR 179

Query: 181 QKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRPQ 240
           ++  D P+     PR    R+ EW+K+  G E  E    L          P   ++    
Sbjct: 180 KEKKDNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKLGTSGYP----PTLVYQNGSI 235

Query: 241 TYVDHMDGS-YSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPM-------HGAGDAKP 292
             V+++D S Y       S  S   + +E+ +      PPPP           G+G A P
Sbjct: 236 GCVENVDASSYPPPPQSDSASSPSPSFSEDNL------PPPPAEFSYPVDNQRGSGLAGP 289

Query: 293 IPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPV 352
             + + S +    + P +P  G  P      P P   P P+              PPPP 
Sbjct: 290 KRSSVVSPS----HPPPAPPLGSPP-----GPKPGFAPPPA--------------PPPPP 326

Query: 353 PP----PPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCE 408
           PP    PPPPP     +P  PPPP+P    P     APPP       P PP A   P   
Sbjct: 327 PPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPP-------PPPPPAADYP--- 376

Query: 409 TVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVP 468
           T+P  PL Q    G PPPPPPP  PPPG              PP    P P T      P
Sbjct: 377 TLPPPPLSQ-PTGGAPPPPPPP--PPPG--------------PP----PPPFTGADGQ-P 414

Query: 469 LMPPSPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIE 528
            +PP       P S+  +  S+LP +SDARS LL AIR+G QLR+VEEQREQE K + + 
Sbjct: 415 AIPP-------PLSDTTKPKSSLPAVSDARSDLLSAIRQGFQLRRVEEQREQE-KRDVVG 466

Query: 529 NDVATILSRRIAVEYSDSEDD-SEFDEVDW 557
           NDVATILSRRIAVEYSDSEDD SEFDE DW
Sbjct: 467 NDVATILSRRIAVEYSDSEDDSSEFDEDDW 496


>gi|13699803 WAS protein family, member 3 [Homo sapiens]
          Length = 502

 Score =  450 bits (1157), Expect = e-126
 Identities = 279/560 (49%), Positives = 324/560 (57%), Gaps = 63/560 (11%)

Query: 1   MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAH 60
           MPLVKRNI+PRHLC  ALP GI +ELECVTN +LA IIRQLSSLSK+AEDIFGELFNEA+
Sbjct: 1   MPLVKRNIEPRHLCRGALPEGITSELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEAN 60

Query: 61  SFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIP 120
           +F  R NSLQ+R+DRL+V VTQLD   EE+SLQDI M+KAF+SST+QDQQ+  + ++P P
Sbjct: 61  NFYIRANSLQDRIDRLAVKVTQLDSTVEEVSLQDINMKKAFKSSTVQDQQVVSKNSIPNP 120

Query: 121 LQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQK 180
           + + Y+  ++PPPLNILTPYRDD K+GLKFYT+PSYFFDLWKEKMLQDTEDKRKEKR+QK
Sbjct: 121 VADIYNQSDKPPPLNILTPYRDDKKDGLKFYTDPSYFFDLWKEKMLQDTEDKRKEKRRQK 180

Query: 181 -QKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRP 239
            QK +D      K  R   +RR+EW  +A   EL  D  N L +   V +G +S     P
Sbjct: 181 EQKRIDGTTREVKKVRKARNRRQEWNMMAYDKELRPD--NRLSQ--SVYHGASSEGSLSP 236

Query: 240 QTYVDHMD-GSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCIS 298
            T     D   YS  A P   +                 P P  P + AGD  P      
Sbjct: 237 DTRSHASDVTDYSYPATPNHSL----------------HPQPVTPSYAAGDVPPHGPASQ 280

Query: 299 SATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPP 358
           +A    E RP S A+ R      P  PPPPPP P A   S   A M     P      P 
Sbjct: 281 AAEH--EYRPPS-ASARHMALNRPQQPPPPPP-PQAPEGSQASAPMA----PADYGMLPA 332

Query: 359 PATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQP-SPPVARAAPVCETVPVHPLPQ 417
                  P+ PPPP P    P V+  A      PL  P  PP   +A      P HP   
Sbjct: 333 QIIEYYNPSGPPPPPP----PPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPST 388

Query: 418 GEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQ 477
           G +   PPPP PPP PPPG                          PGP   L   S P  
Sbjct: 389 GLLVTAPPPPGPPP-PPPG-------------------------PPGPGSSL--SSSPMH 420

Query: 478 VIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSR 537
             P +E KR     P ISDARS LL AIR GIQL+KV+EQREQEAK E + NDVATILSR
Sbjct: 421 GPPVAEAKRQEPAQPPISDARSDLLAAIRMGIQLKKVQEQREQEAKREPVGNDVATILSR 480

Query: 538 RIAVEYSDSEDDSEFDEVDW 557
           RIAVEYSDS+DDSEFDE DW
Sbjct: 481 RIAVEYSDSDDDSEFDENDW 500


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score =  113 bits (283), Expect = 4e-25
 Identities = 84/232 (36%), Positives = 99/232 (42%), Gaps = 49/232 (21%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPP------PPPPPL 331
            PPPPPP+ GAG   P P       G++   P  P  G     + P PP      PPPPPL
Sbjct: 909  PPPPPPLPGAGIPPPPPL---PGAGILP-LPPLPGAG-----IPPPPPLPGAAIPPPPPL 959

Query: 332  PSALSTSSLRASMTSTPPPPVPP----PPPPPATALQAPAVP-------PPPAPLQIAPG 380
            P A             PPPP  P    PPPPP      P  P       PPP PL   PG
Sbjct: 960  PGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL---PG 1016

Query: 381  VLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPP--------PPPPPL 432
               P PPP+    + P PP+    P     P  PLP     G+PPP        PPPPPL
Sbjct: 1017 AGIPPPPPLPGAGIPPPPPL----PGAGIPPPPPLPGA---GIPPPPPLPGAGIPPPPPL 1069

Query: 433  PPPGIRPSSPVTVTALAHPP----SGLHPTPSTAPGPHVPLMPPSPPSQVIP 480
            P  GI P  P+    +  PP    +G+ P P   PG  +P  PP P + + P
Sbjct: 1070 PGAGIPPPPPLPGAGIPPPPPLPGAGI-PPPPPLPGVGIPPPPPLPGAGIPP 1120



 Score =  112 bits (279), Expect = 1e-24
 Identities = 84/224 (37%), Positives = 101/224 (45%), Gaps = 56/224 (25%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPP------PPPPPL 331
            PPPPPP+ G      +PT  S+A       PQ P    T +   P PP      PPPPPL
Sbjct: 877  PPPPPPLPGM----TVPTLPSTAI------PQPPPLQGTEMLPPPPPPLPGAGIPPPPPL 926

Query: 332  PSALSTSSLRASMTSTPPPPVPP---PPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPP 388
            P A             P PP+P    PPPPP   L   A+PPPP PL   PG   P PPP
Sbjct: 927  PGA----------GILPLPPLPGAGIPPPPP---LPGAAIPPPP-PL---PGAGIPLPPP 969

Query: 389  IAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPP--------PPPPPLPPPGIRPS 440
            +    + P PP+    P     P  PLP     G+PPP        PPPPPLP  GI P 
Sbjct: 970  LPGAGIPPPPPL----PGAGIPPPPPLPGA---GIPPPPPLPGAGIPPPPPLPGAGIPPP 1022

Query: 441  SPVTVTALAHPP----SGLHPTPSTAPGPHVPLMPPSPPSQVIP 480
             P+    +  PP    +G+ P P   PG  +P  PP P + + P
Sbjct: 1023 PPLPGAGIPPPPPLPGAGI-PPPPPLPGAGIPPPPPLPGAGIPP 1065



 Score =  110 bits (275), Expect = 3e-24
 Identities = 83/228 (36%), Positives = 98/228 (42%), Gaps = 43/228 (18%)

Query: 279  PPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPP------PPPPPLP 332
            PPPPP+ GAG   P P   +     I   P  P  G     + P PP      PPPPPLP
Sbjct: 976  PPPPPLPGAGIPPPPPLPGAG----IPPPPPLPGAG-----IPPPPPLPGAGIPPPPPLP 1026

Query: 333  SALSTSSLRASMTSTPPPPVPP----PPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPP 388
             A             PPPP  P    PPPPP   L    +PPPP PL   PG   P PPP
Sbjct: 1027 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP---LPGAGIPPPP-PL---PGAGIPPPPP 1079

Query: 389  IAPPLVQPSPPVARAA----PVCETVPVHPLPQGEVQGLPPP--------PPPPPLPPPG 436
            +    + P PP+  A     P    V + P P     G+PPP        PPPPPLP  G
Sbjct: 1080 LPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1139

Query: 437  IRPSSPVTVTALAHPP----SGLHPTPSTAPGPHVPLMPPSPPSQVIP 480
            I P  P+    +  PP    +G+ P P   PG  +P  PP P   + P
Sbjct: 1140 IPPPPPLPRVGIPPPPPLPGAGI-PPPPPLPGAGIPPPPPLPGVGIPP 1186



 Score =  106 bits (265), Expect = 5e-23
 Identities = 86/230 (37%), Positives = 99/230 (43%), Gaps = 54/230 (23%)

Query: 279  PPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPP------PPPPPLP 332
            PPPPP+ GAG   P P   +     I   P  P  G     + P PP      PPPPPLP
Sbjct: 1064 PPPPPLPGAGIPPPPPLPGAG----IPPPPPLPGAG-----IPPPPPLPGVGIPPPPPLP 1114

Query: 333  SALSTSSLRASMTSTPPPPVPP---PPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPI 389
             A             PPPP+P    PPPPP   L    +PPPP PL   P V  P PPP+
Sbjct: 1115 GA----------GIPPPPPLPGAGIPPPPP---LPGAGIPPPP-PL---PRVGIPPPPPL 1157

Query: 390  APPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALA 449
                + P PP+    P     P  PLP   +      PPPPPLP  GI P  P+    + 
Sbjct: 1158 PGAGIPPPPPL----PGAGIPPPPPLPGVGI------PPPPPLPGVGIPPPPPLPGAGIP 1207

Query: 450  HPPSGLHPTPSTAPGPHVPLMPPS---PPSQVIPASEPKRHP----STLP 492
             PP    P     P P  PL PP    PP  ++P S P   P    STLP
Sbjct: 1208 PPPP--LPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLP 1255



 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 76/210 (36%), Positives = 88/210 (41%), Gaps = 60/210 (28%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPP------PPPPPL 331
            PPPP P  GAG   P               P  P  G     + P PP      PPPPPL
Sbjct: 1109 PPPPLP--GAGIPPP---------------PPLPGAG-----IPPPPPLPGAGIPPPPPL 1146

Query: 332  PSALSTSSLRASMTSTPPPPVP----PPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPP 387
            P           +   PPPP+P    PPPPP    L    +PPPP PL   PGV  P PP
Sbjct: 1147 P----------RVGIPPPPPLPGAGIPPPPP----LPGAGIPPPP-PL---PGVGIPPPP 1188

Query: 388  PIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTA 447
            P+    + P PP+    P     P  PLP   +    PP P PPLPPPG     P  +  
Sbjct: 1189 PLPGVGIPPPPPL----PGAGIPPPPPLPGMGI----PPAPAPPLPPPG-TGIPPPPLLP 1239

Query: 448  LAHPPSGLHPTPSTAPGPHV-PLMPPSPPS 476
            ++ PP       ST P P V   +PP  PS
Sbjct: 1240 VSGPPLLPQVGSSTLPTPQVCGFLPPPLPS 1269



 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 65/176 (36%), Positives = 74/176 (42%), Gaps = 34/176 (19%)

Query: 279  PPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTP------VFVSPTPP------P 326
            PPPPP+ GAG   P P   +     I   P  P  G  P      V + P PP      P
Sbjct: 1108 PPPPPLPGAGIPPPPPLPGAG----IPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIP 1163

Query: 327  PPPPLPSALSTSSLRASMTSTPPPP------VPPPPPPPATALQAPAVPPPPAP-LQIAP 379
            PPPPLP A             PPPP      +PPPPP P   +     PPPP P + I P
Sbjct: 1164 PPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIP----PPPPLPGMGIPP 1219

Query: 380  GVLHPAPPP---IAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPL 432
                P PPP   I PP   P  PV+   P+   V    LP  +V G  PPP P  L
Sbjct: 1220 APAPPLPPPGTGIPPP---PLLPVS-GPPLLPQVGSSTLPTPQVCGFLPPPLPSGL 1271



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 67/244 (27%), Positives = 85/244 (34%), Gaps = 68/244 (27%)

Query: 275 PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPL--- 331
           P  PP PP   GA        C   +  +   R         P      PPPPP  L   
Sbjct: 764 PGRPPCPP---GAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSA 820

Query: 332 ---------PSALSTS-------SLRASMTSTPPPPVPPPPPPPATALQAPA---VPPPP 372
                    P ++ST        S+ ++  ++   P PPP P   ++   P    VPPPP
Sbjct: 821 GQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPP 880

Query: 373 APLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPL 432
            PL   PG+  P  P  A P  QP P                     +QG    PPPPP 
Sbjct: 881 PPL---PGMTVPTLPSTAIP--QPPP---------------------LQGTEMLPPPPP- 913

Query: 433 PPP-------------GIRPSSPVTVTALAHP---PSGLHPTPSTAPGPHVPLMPPSPPS 476
           P P             GI P  P+    +  P   P    P P   PG  +PL PP P +
Sbjct: 914 PLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGA 973

Query: 477 QVIP 480
            + P
Sbjct: 974 GIPP 977



 Score = 37.7 bits (86), Expect = 0.028
 Identities = 32/90 (35%), Positives = 35/90 (38%), Gaps = 10/90 (11%)

Query: 279  PPPPPMHGAG-DAKPIPTCISSATGLIENRPQSPATGRT--PVFVSPTPPPP------PP 329
            PPPPP+ G G    P P      TG I   P  P +G    P   S T P P      PP
Sbjct: 1207 PPPPPLPGMGIPPAPAPPLPPPGTG-IPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPP 1265

Query: 330  PLPSALSTSSLRASMTSTPPPPVPPPPPPP 359
            PLPS L    +     S   P  P  P  P
Sbjct: 1266 PLPSGLFGLGMNQDKGSRKQPIEPCRPMKP 1295


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score =  111 bits (278), Expect = 2e-24
 Identities = 95/298 (31%), Positives = 122/298 (40%), Gaps = 85/298 (28%)

Query: 273 VRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPP------ 326
           +R   PPPPPP  G     P P   S         P  PA GR     +P PPP      
Sbjct: 272 LRRQAPPPPPPSRGGPPPPPPPPHNSGP-------PPPPARGRG----APPPPPSRAPTA 320

Query: 327 -PPPPLPSALSTSSLRASMTSTPPPPVPP-PPPPPATALQAPAVPPPPAPLQIAPGVLHP 384
            PPPP PS       R S+   PPPP    PPPPPA    AP+ PPPP P  +  G + P
Sbjct: 321 APPPPPPS-------RPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAP 373

Query: 385 APPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVT 444
            PPP  PP                               PPPP PP  PPPG+       
Sbjct: 374 PPPP--PP-------------------------------PPPPGPP--PPPGL------- 391

Query: 445 VTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKR-HPSTLPVISDARSVLLE 503
                 P  G H  P+TA G    L+      Q+   ++ K+   ++ PV    R  LL+
Sbjct: 392 ------PSDGDHQVPTTA-GNKAALL-----DQIREGAQLKKVEQNSRPVSCSGRDALLD 439

Query: 504 AIRKGIQLRKVEEQREQ----EAKHERIENDVATILSRRIAVEYSDSEDDSEFDEVDW 557
            IR+GIQL+ V + +E      A    I   +  ++ +R    +S  ED+ E DE D+
Sbjct: 440 QIRQGIQLKSVADGQESTPPTPAPTSGIVGALMEVMQKRSKAIHSSDEDEDEDDEEDF 497



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 30/86 (34%), Positives = 36/86 (41%), Gaps = 12/86 (13%)

Query: 417 QGEVQGLPPPPPPP-------PLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPL 469
           + E++   PPPPPP       P PPP      P        PP    P PS AP    P 
Sbjct: 269 KNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPP----PPPSRAPTAAPPP 324

Query: 470 MPPSPPSQVIPASEPKR-HPSTLPVI 494
            PPS PS  +P   P R +P   P +
Sbjct: 325 PPPSRPSVAVPPPPPNRMYPPPPPAL 350


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score =  101 bits (251), Expect = 2e-21
 Identities = 94/281 (33%), Positives = 112/281 (39%), Gaps = 67/281 (23%)

Query: 275 PHEPPPPPPMHG-----AGDAKPIPTCISSATGLIENRPQSPATGRTP------------ 317
           P  PPPPPP+       AG A P+    S+ T L      S A  + P            
Sbjct: 640 PPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKP 699

Query: 318 -VFVSPT----PPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQ-------A 365
            + V P     PPPPPPP P+  S  +        P  P    PPPP    Q       A
Sbjct: 700 QILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVA 759

Query: 366 PAVPPPPAPLQIAPGVLHPAPPPIAPPLV---------QPSPPVARAAPVCETVPVHPL- 415
           P  PPPP P+   P  L P  PP   PLV           +P V +AAP   T PV P  
Sbjct: 760 PPTPPPPPPI---PAPLPPQAPP--KPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAK 814

Query: 416 --PQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAH-PPSGLHPTPSTA--------PG 464
             P      +PP PP PP+P P   P+ P   +  A  PPS L P PS          P 
Sbjct: 815 KQPAFPASYIPPSPPTPPVPVP--PPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPP 872

Query: 465 PHVPLMPPSP----PSQVIPAS------EPKRHPSTLPVIS 495
           P  P M   P    P+ V P S      +PK  PS++PV S
Sbjct: 873 PTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPS 913



 Score = 98.2 bits (243), Expect = 2e-20
 Identities = 76/243 (31%), Positives = 103/243 (42%), Gaps = 37/243 (15%)

Query: 273 VRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP 332
           V P  PPPPPP+       P+P        +    P S  T   PV     PP P PP+P
Sbjct: 758 VAPPTPPPPPPIPA-----PLPPQAPPKPLVTIPAPTSTKTV-APVVTQAAPPTPTPPVP 811

Query: 333 SALSTSSLRAS-MTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA----PP 387
            A    +  AS +  +PP P  P PPP     Q+    PPP+PL   P V+       PP
Sbjct: 812 PAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPP 871

Query: 388 PIAPPLVQ-------------PSPPVARAAPVCE--TVPV------HPLPQGEVQGLPPP 426
           P  PP ++              SPP  +A P  +  ++PV       P P+  +   PPP
Sbjct: 872 PPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPP 931

Query: 427 PPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPP-SQVIPASEPK 485
           P P P PPP   P++  T      P  G   + +++PG   P  PP+P  +  I +S   
Sbjct: 932 PSPVPAPPPPPPPTASPTPDKSGSP--GKKTSKTSSPGGKKP--PPTPQRNSSIKSSSGA 987

Query: 486 RHP 488
            HP
Sbjct: 988 EHP 990



 Score = 90.1 bits (222), Expect = 5e-18
 Identities = 62/205 (30%), Positives = 81/205 (39%), Gaps = 43/205 (20%)

Query: 326 PPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA 385
           PP  P P  ++  +      S P PP+PPPPPPP      P  PPPP P Q AP     A
Sbjct: 607 PPLSPQPKIVTPYT-----ASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAA 661

Query: 386 PPPIAPPLV---------------QPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPP 430
           P  +    +                P+PPV ++  V   + V   P G V   PPPPPPP
Sbjct: 662 PMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVP--PNGVV---PPPPPPP 716

Query: 431 PLPPPG------------------IRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPP 472
           P P PG                    P  P+ +  + H      PTP   P    PL P 
Sbjct: 717 PPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQ 776

Query: 473 SPPSQVIPASEPKRHPSTLPVISDA 497
           +PP  ++    P    +  PV++ A
Sbjct: 777 APPKPLVTIPAPTSTKTVAPVVTQA 801



 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 80/303 (26%), Positives = 105/303 (34%), Gaps = 93/303 (30%)

Query: 233 SHFETRPQTYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKP 292
           +  E   +  ++ M+  Y+    P S   +++T         P  PPPPPP         
Sbjct: 585 TQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPP--------- 635

Query: 293 IPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRAS--------- 343
                          P  P          P PPPPPPPLPS  + S+  A+         
Sbjct: 636 ---------------PPPP----------PPPPPPPPPLPSQSAPSAGSAAPMFVKYSTI 670

Query: 344 ------------MTSTPPPPV-------PPPPPPPATALQAPAVPPPPAPLQIAPGVLHP 384
                       +   P PPV       P    PP   +  P  PPPP     A   L P
Sbjct: 671 TRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKP 730

Query: 385 AP-PPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLP---PPGIRPS 440
           AP  P  P    P PP          + +H +        P PPPPPP+P   PP   P 
Sbjct: 731 APCAPSLPQFSAPPPP----------LKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPK 780

Query: 441 SPVTVTA------------LAHPPSGLHPTPSTA-----PGPHVPLMPPSPPSQVIPASE 483
             VT+ A             A PP+   P P        P  ++P  PP+PP  V P + 
Sbjct: 781 PLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTL 840

Query: 484 PKR 486
           PK+
Sbjct: 841 PKQ 843



 Score = 80.1 bits (196), Expect = 5e-15
 Identities = 72/242 (29%), Positives = 89/242 (36%), Gaps = 75/242 (30%)

Query: 306 NRPQS---PATGRTPVFVSP-TPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPAT 361
           NRP +   P     P  V+P T   P PPLP               PPPP PPPPPPP  
Sbjct: 599 NRPYTSLVPPLSPQPKIVTPYTASQPSPPLP---------------PPPPPPPPPPPP-- 641

Query: 362 ALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ---------------PSPPVARAAPV 406
               P  PPPP P Q AP     AP  +    +                P+PPV ++  V
Sbjct: 642 ----PPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSV 697

Query: 407 CETVPVHPLPQGEVQGLPPPPPPPPLPPPGIR------------------PSSPVTVTAL 448
              + V P   G V   PPPPPPPP P PG                    P  P+ +  +
Sbjct: 698 KPQILVPP--NGVV---PPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQV 752

Query: 449 AH-----PPSGLHPTPSTAP-------GPHVPLMPPSPPSQVIPASEPKRHPSTLPVISD 496
            H     PP+   P P  AP        P V +  P+    V P       P+  P +  
Sbjct: 753 QHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPP 812

Query: 497 AR 498
           A+
Sbjct: 813 AK 814



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 63/270 (23%), Positives = 94/270 (34%), Gaps = 66/270 (24%)

Query: 278  PPPPPPMHGAGDAKPIPTCIS-SATGLIENRPQ-----------------------SPAT 313
            PPP PP   +   KP+P  ++  +   ++ +P+                        P  
Sbjct: 871  PPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPP 930

Query: 314  GRTPVFVSPTPPPP-PPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPP 372
              +PV   P PPPP   P P    +   + S TS+P    PPP P   +++++ +    P
Sbjct: 931  PPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHP 990

Query: 373  APLQIAPGVL---------------HPAPPPIAPPLVQPS---------PPVARAAPVCE 408
             P + +   L                  PPP APP  +P          P V +   V  
Sbjct: 991  EPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPP--KPGKLNLSGVNLPGVLQQGCVSA 1048

Query: 409  TVPV-HPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHV 467
              PV     +  V   P PP     PPP      P+       PP  +    S    P V
Sbjct: 1049 KAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPL-------PPIEIPAVFSGNTSPKV 1101

Query: 468  PLMPPSPP-------SQVIPASEPKRHPST 490
             ++ P P         +  P + PKR+ ST
Sbjct: 1102 AVVNPQPQQWSKMSVKKAPPPTRPKRNDST 1131


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 97.1 bits (240), Expect = 4e-20
 Identities = 85/272 (31%), Positives = 113/272 (41%), Gaps = 47/272 (17%)

Query: 252 LSALPFSQMSELLTRAEERVLVRPHEPPPP---PPMHGAGDAKPIPTCISSATGLIENRP 308
           L  LP   +S L T         P + PP    PP+     A P P      + L    P
Sbjct: 603 LQGLPSPPLSPLATP--------PPQAPPXLALPPLQ----APPSPPASPPLSPLATPSP 650

Query: 309 QSPATGRTPVFVSPTPPPPPPPLPSALS-TSSLRASMTSTPP---------PPVPPPPPP 358
           Q+P      +  +P  PPP PP+ +  S  +S   S ++TPP         PP+  PP P
Sbjct: 651 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 710

Query: 359 PATALQAP-AVPPPPAPLQI-APGVLHPAPPPIAPPLVQPSPPVARAAPVCETVP--VHP 414
           PA+   +P A PPP AP  + AP +  P  PP +PP+   + P  R  P+    P  V P
Sbjct: 711 PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPP 770

Query: 415 LPQGEVQGLP---PPPPPPP---LPPPGIRPSSPVTVTALA--HPPSGLHPTPSTAPGPH 466
            P   +   P   PPP  PP    PP    PS P +    A   P + L  +P   P P 
Sbjct: 771 SPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ 830

Query: 467 VP--------LMPPSPPSQVIPASEPKRHPST 490
            P         +PPSPP+   P  +  R P T
Sbjct: 831 APPVLAAPLLQVPPSPPAS--PTLQAPRRPPT 860



 Score = 93.2 bits (230), Expect = 6e-19
 Identities = 85/267 (31%), Positives = 108/267 (40%), Gaps = 51/267 (19%)

Query: 272 LVRPHEPPPP-----PPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSP---- 322
           L  P    PP     PP+       P P   +SA     +    P     P+   P    
Sbjct: 518 LAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLT 577

Query: 323 TPPP--------PPPPLPSALSTSSLRA------SMTSTPPPPVPP---------PPPPP 359
           TPPP        PPP  P AL++  L+       S  +TPPP  PP         PP PP
Sbjct: 578 TPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPP 637

Query: 360 ATALQAP-AVPPPPAPLQIAPGVLH-PAPPPIAPPLVQP-SPPVARAAPVCETVPVHPLP 416
           A+   +P A P P AP  +A  +L  P  PP +PP+  P SPP +       T P    P
Sbjct: 638 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 697

Query: 417 QGEVQGLPPPPPPPPLPP--PGIRPSSPVTVTALAHPPSGLHP--------TPSTAPGPH 466
                 L  PP PP  PP  P   P  P     LA PP  + P        +PS  P P 
Sbjct: 698 SLAAPPLQVPPSPPASPPMSPSATP-PPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPR 756

Query: 467 VPLMPPSPPSQVIPASEPKRHPSTLPV 493
           VP +  +PP QV P+      P++LP+
Sbjct: 757 VPPLLAAPPLQVPPSP-----PASLPM 778



 Score = 88.6 bits (218), Expect = 1e-17
 Identities = 72/232 (31%), Positives = 93/232 (40%), Gaps = 38/232 (16%)

Query: 271 VLVRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPAT---------GRTPVFVS 321
           +L  P  PPP PP+         P    SAT   +  P   A             P+  S
Sbjct: 660 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 719

Query: 322 PTPPP-PPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPP--APLQIA 378
            TPPP  PPPL +                PP+  PP PPA+   +P+  PPP   PL  A
Sbjct: 720 ATPPPQAPPPLAA----------------PPLQVPPSPPASPPMSPSATPPPRVPPLLAA 763

Query: 379 PGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIR 438
           P +  P  PP + P+   + P  +A P   T P        +Q LP PP   P   P   
Sbjct: 764 PPLQVPPSPPASLPMSPLAKPPPQAPPALATPP--------LQALPSPPASFPGQAP-FS 814

Query: 439 PSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPST 490
           PS+ + ++ LA PP    P    AP   VP  PP+ P+   P   P   P T
Sbjct: 815 PSASLPMSPLATPPPQAPPV-LAAPLLQVPPSPPASPTLQAPRRPPTPGPDT 865



 Score = 76.3 bits (186), Expect = 7e-14
 Identities = 84/280 (30%), Positives = 113/280 (40%), Gaps = 49/280 (17%)

Query: 264 LTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISS-ATGL---IENRPQSPATGRTPVF 319
           ++ A E     P       P  G G  +P    +SS AT L     + P +  T R P  
Sbjct: 209 VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 268

Query: 320 VSPTPP-------PP---PPPLPSALSTSSLRASMTSTPPP------PVPPP----PPPP 359
            S   P       PP   PP   +A +   L +S  +TP P      PVPPP     P P
Sbjct: 269 PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLP 328

Query: 360 ATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ--PSPPV---ARAAPVCETVPVHP 414
           AT    P  PP   PL +AP      P P APP +Q  PSPP    ++A P   T P+  
Sbjct: 329 AT---LPPSPPLATPLPLAP------PSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQA 379

Query: 415 LPQGEVQGLPPPPPPPPLPPPGIR-PSSPVTVTALAHPPSGLHPTPSTAPG--------P 465
            P   +Q +PP   P  L  P ++ P SP+ +++L    S   PT               
Sbjct: 380 PP--SLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQT 437

Query: 466 HVPLMPPSPPSQVIPASEPKRHPSTLPVISDARSVLLEAI 505
              L  PS P+   P S P + P +LP     ++ L  A+
Sbjct: 438 QASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAV 477



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 86/286 (30%), Positives = 108/286 (37%), Gaps = 54/286 (18%)

Query: 248 GSYSLSAL-PFSQMSELLTRAEERVLVRPHEPPPP-PPMHGAGD---AKPIPTCISSATG 302
           GS +L A   F  MS   T+A      RP   PP  PP+        + P+ T +S A  
Sbjct: 419 GSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVS 478

Query: 303 LIENRPQSPATGRTPVFVSPTPPPP-----PPPLP--SALSTSSLR---ASMTSTPPPPV 352
            + +              S +P  P      PPL   S+L+  SL+   AS+T+ P   +
Sbjct: 479 PLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENL 538

Query: 353 PPPPPPPATALQAPAVPP--------PPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAA 404
           P   PPP     AP   P         P PLQ  P  L   PPP  P  +   PP  +A 
Sbjct: 539 PSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPL-TTPPPETPSSIATPPP--QAP 595

Query: 405 PVCETVPVHPLPQGEVQGLPPPPPPPP----LPPPGIRPSSPVTVTALAHPPSGLHPTPS 460
           P   + P+  LP   +  L  PPP  P    LPP    PS P      A PP     +P 
Sbjct: 596 PALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPP------ASPPL----SPL 645

Query: 461 TAPGPHVP------------LMPPSPPSQV--IPASEPKRHPSTLP 492
             P P  P              PPSPP Q    P + P   PS  P
Sbjct: 646 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 691



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 76/285 (26%), Positives = 107/285 (37%), Gaps = 85/285 (29%)

Query: 279 PPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPP---LPSAL 335
           P PPP + A    P+P  +  +  L    P +P +   P  +   P PP  P    P ++
Sbjct: 316 PVPPPDNAA---TPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSM 372

Query: 336 STSSLRA--SMTSTPPPPVP----------PPPPPPATALQAPAVPPPP----------- 372
           +T  ++A  S+ + PP  VP          PP P   ++LQA      P           
Sbjct: 373 TTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTM 432

Query: 373 APLQIAPGVLHP----APPPIAPPLVQP-----SPPVARA-----APVCETVPVHPL--- 415
           +P Q    +  P    + PP +PPL  P     SPP+  +     +P+   + +HPL   
Sbjct: 433 SPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQAL 492

Query: 416 -------PQGEVQGLPPPP--------PP-----------PPL-------PPPGIRPSSP 442
                  PQ  +  L  PP        PP           PPL       PPP    S+P
Sbjct: 493 SSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAP 552

Query: 443 VTVTALAHPPS------GLHPTPSTAPGPHVPLMPPSPPSQVIPA 481
           +T   L  PP          P+P T P P  P    +PP Q  PA
Sbjct: 553 LTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPA 597



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 66/211 (31%), Positives = 83/211 (39%), Gaps = 29/211 (13%)

Query: 280 PPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSS 339
           P PP  G   +      +SSA+      P SPA  R P        P    L S+ +  S
Sbjct: 198 PRPPTEGPRKS------VSSASEHSTTEP-SPAARRRPSAGGGLQRPASRSLSSSATPLS 250

Query: 340 LRA----SMTSTPPPPVPPPPPPPA--TALQAPAVPPPPAPLQIAPGVLHPAP---PPIA 390
             A    S   TP  P  P  P P    AL+ P V PP      A G L  +P   P  +
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 310

Query: 391 PPLVQPSPPVARAA-PVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIR--PSSPVTVTA 447
               +P PP   AA P+  T+P    P   +    P  PP P  PP ++  PS P T   
Sbjct: 311 GTKARPVPPPDNAATPLPATLP----PSPPLATPLPLAPPSPSAPPSLQTLPSPPAT--- 363

Query: 448 LAHPPSGLHPTPSTAPGPHVPLMPPSPPSQV 478
              PPS   P+ +T P    P +   PP QV
Sbjct: 364 ---PPSQAPPSMTTPPMQAPPSLQTIPPIQV 391



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 53/189 (28%), Positives = 72/189 (38%), Gaps = 31/189 (16%)

Query: 322 PTPPPPPPPLPSALSTSSL-----RASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQ 376
           PTP  P P +      +       R + ++ P PP   P    ++A +     P PA  +
Sbjct: 167 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226

Query: 377 ---IAPGVLHPAPPPI---APPLVQP--SPPVARAAPVCETVPVHPLPQGEVQGLPPPPP 428
                 G+  PA   +   A PL  P  S P AR  P     P  P P+G +Q L PP  
Sbjct: 227 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG-LQALRPPQV 285

Query: 429 PPP----LPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEP 484
            PP     P  G   SSP+             P+PS      VP  PP   +  +PA+ P
Sbjct: 286 TPPRKDAAPALGPLSSSPLAT-----------PSPSGTKARPVP--PPDNAATPLPATLP 332

Query: 485 KRHPSTLPV 493
              P   P+
Sbjct: 333 PSPPLATPL 341



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 55/184 (29%), Positives = 68/184 (36%), Gaps = 38/184 (20%)

Query: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATG------RTPVFVSPTPPPPPPPL 331
           PP  PP+  A   +  P+  +S T     RP +P         R  + ++P PPPPP   
Sbjct: 828 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 887

Query: 332 PSA-LSTSSLR---ASMTSTP---------PPPVPPPPPPPATALQA--PAV----PPPP 372
           PS+ LS   L    +S TSTP         P       PPP   L A  PA     P PP
Sbjct: 888 PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPP 947

Query: 373 APLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPL 432
              + APG   P PP   P           A  +C         +G     P P    P 
Sbjct: 948 LAFRGAPGAPLPWPPATGP---------GSADGLCTIYET----EGPESATPAPGALDPG 994

Query: 433 PPPG 436
           P PG
Sbjct: 995 PSPG 998



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 54/218 (24%), Positives = 75/218 (34%), Gaps = 40/218 (18%)

Query: 309 QSPATGRTPVFVSPTPP----PPPPPLPSALSTSSLRASMTSTP---------------P 349
           ++PA  R P  ++P PP    PPPP  P+AL       ++   P                
Sbjct: 15  RTPAA-RAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES 73

Query: 350 PPVPPPPPPPATALQAPAVPPPPAPL-QIAPGVLHPAPPPIAPP-----LVQPSP----- 398
            P   P     T+ + PA  PP +   + AP   + +P P++ P       +P P     
Sbjct: 74  APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 133

Query: 399 -------PVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP 451
                   VAR     E      L  G  +    P P  P P    R  +  T   L  P
Sbjct: 134 LRISAEETVAR-GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 192

Query: 452 PSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPS 489
                P P T  GP   +   S  S   P+   +R PS
Sbjct: 193 APSARPRPPT-EGPRKSVSSASEHSTTEPSPAARRRPS 229



 Score = 37.7 bits (86), Expect = 0.028
 Identities = 56/200 (28%), Positives = 71/200 (35%), Gaps = 51/200 (25%)

Query: 333 SALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPA----PLQIAPGVLHPAPPP 388
           +A  T + RA    TP PP  P PPPP T      +    A    PL    G +  A  P
Sbjct: 12  AAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71

Query: 389 IAPPLVQPS-------------PPVA----RAAPVCETVPVHPLPQGEVQGLPPPPPPPP 431
            + P   P+             PP +    RA P   T P      G   G      P P
Sbjct: 72  ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASG---TTRPGP 128

Query: 432 LPPPGIRPSSPVTV-----------TALA----HPPSGLHPTPST----------APGPH 466
           L   G+R S+  TV           +AL+       SG  PTP T          A G  
Sbjct: 129 LGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG--PTPGTPSPAMARRSRAAGTE 186

Query: 467 VPLMPPSPPSQVIPASEPKR 486
           V L  P+P ++  P +E  R
Sbjct: 187 VGLPRPAPSARPRPPTEGPR 206


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 94.4 bits (233), Expect = 3e-19
 Identities = 100/361 (27%), Positives = 132/361 (36%), Gaps = 89/361 (24%)

Query: 163 EKMLQDTEDKRK-EKRKQKQKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLL 221
           E ++    DK K EK + K   L++  + E   R  H+ + E +K+    E    D   L
Sbjct: 453 EGLIDQMIDKTKVEKSEAKAAELEKKLDSELTAR--HELQVEMKKMESDFEQKLQD---L 507

Query: 222 HKHIEVANGPASHFETRPQTY---VDHMDGSYS-LSALPFSQMSELLTRAEERVLVRPHE 277
               +  +       T  Q     V  + G  + L+        E+ + +   + V P  
Sbjct: 508 QGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSV 567

Query: 278 P-----PPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP 332
           P     PP PP+ G              +G I   P +P    TP    P PPPPPPPLP
Sbjct: 568 PSRAPVPPAPPLPGD-------------SGTIIPPPPAPGDSTTPP-PPPPPPPPPPPLP 613

Query: 333 SALSTSS---------------LRASMTSTPPPP------------------VPPPPPPP 359
             +  SS               L    T  PPPP                  +PPPPP P
Sbjct: 614 GGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLP 673

Query: 360 ATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGE 419
            +A     +PPPP PL  + G+  P PPP+      P PP              PLP G 
Sbjct: 674 GSA----RIPPPPPPLPGSAGI-PPPPPPLPGEAGMPPPP-------------PPLPGG- 714

Query: 420 VQGLPPPPP-------PPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPP 472
             G+PPPPP       PPP P  G+ P  P      A P      TP     P V L  P
Sbjct: 715 -PGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLRRP 773

Query: 473 S 473
           +
Sbjct: 774 N 774



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 43/138 (31%), Positives = 52/138 (37%), Gaps = 39/138 (28%)

Query: 373 APLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPL 432
           A + + P V   AP P APPL   S  +         +P  P P         PPPPPP 
Sbjct: 559 AAITVPPSVPSRAPVPPAPPLPGDSGTI---------IPPPPAPGDSTT----PPPPPPP 605

Query: 433 PPP--------------------GIRPSSPVTVTALAHPPSGLH-----PTPSTAP-GPH 466
           PPP                     I P  P++  A   PP  L      P+PS+ P G  
Sbjct: 606 PPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTA 665

Query: 467 VPLMPPSPPSQVIPASEP 484
           +P  PP P S  IP   P
Sbjct: 666 IPPPPPLPGSARIPPPPP 683



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 36/106 (33%), Positives = 45/106 (42%), Gaps = 20/106 (18%)

Query: 398 PPVARAAPVCETVPVHPLPQGEVQGLPPPPPP-----PPLPPPGIRPSSPVT-VTALAHP 451
           P V   APV    P  PLP      +PPPP P     PP PPP   P  P+     ++ P
Sbjct: 565 PSVPSRAPV---PPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSP 621

Query: 452 PS-----GLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLP 492
           PS      + P P  +    +P  PP P    IP+      PS+LP
Sbjct: 622 PSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPS------PSSLP 661


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 94.4 bits (233), Expect = 3e-19
 Identities = 100/361 (27%), Positives = 132/361 (36%), Gaps = 89/361 (24%)

Query: 163 EKMLQDTEDKRK-EKRKQKQKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLL 221
           E ++    DK K EK + K   L++  + E   R  H+ + E +K+    E    D   L
Sbjct: 462 EGLIDQMIDKTKVEKSEAKAAELEKKLDSELTAR--HELQVEMKKMESDFEQKLQD---L 516

Query: 222 HKHIEVANGPASHFETRPQTY---VDHMDGSYS-LSALPFSQMSELLTRAEERVLVRPHE 277
               +  +       T  Q     V  + G  + L+        E+ + +   + V P  
Sbjct: 517 QGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSV 576

Query: 278 P-----PPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP 332
           P     PP PP+ G              +G I   P +P    TP    P PPPPPPPLP
Sbjct: 577 PSRAPVPPAPPLPGD-------------SGTIIPPPPAPGDSTTPP-PPPPPPPPPPPLP 622

Query: 333 SALSTSS---------------LRASMTSTPPPP------------------VPPPPPPP 359
             +  SS               L    T  PPPP                  +PPPPP P
Sbjct: 623 GGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLP 682

Query: 360 ATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGE 419
            +A     +PPPP PL  + G+  P PPP+      P PP              PLP G 
Sbjct: 683 GSA----RIPPPPPPLPGSAGI-PPPPPPLPGEAGMPPPP-------------PPLPGG- 723

Query: 420 VQGLPPPPP-------PPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPP 472
             G+PPPPP       PPP P  G+ P  P      A P      TP     P V L  P
Sbjct: 724 -PGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLRRP 782

Query: 473 S 473
           +
Sbjct: 783 N 783



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 43/138 (31%), Positives = 52/138 (37%), Gaps = 39/138 (28%)

Query: 373 APLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPL 432
           A + + P V   AP P APPL   S  +         +P  P P         PPPPPP 
Sbjct: 568 AAITVPPSVPSRAPVPPAPPLPGDSGTI---------IPPPPAPGDSTT----PPPPPPP 614

Query: 433 PPP--------------------GIRPSSPVTVTALAHPPSGLH-----PTPSTAP-GPH 466
           PPP                     I P  P++  A   PP  L      P+PS+ P G  
Sbjct: 615 PPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTA 674

Query: 467 VPLMPPSPPSQVIPASEP 484
           +P  PP P S  IP   P
Sbjct: 675 IPPPPPLPGSARIPPPPP 692



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 36/106 (33%), Positives = 45/106 (42%), Gaps = 20/106 (18%)

Query: 398 PPVARAAPVCETVPVHPLPQGEVQGLPPPPPP-----PPLPPPGIRPSSPVT-VTALAHP 451
           P V   APV    P  PLP      +PPPP P     PP PPP   P  P+     ++ P
Sbjct: 574 PSVPSRAPV---PPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSP 630

Query: 452 PS-----GLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLP 492
           PS      + P P  +    +P  PP P    IP+      PS+LP
Sbjct: 631 PSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPS------PSSLP 670


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 94.4 bits (233), Expect = 3e-19
 Identities = 71/251 (28%), Positives = 89/251 (35%), Gaps = 40/251 (15%)

Query: 275  PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSA 334
            P   P PPP          PT   S        P    T   P+  + TPPP   P P  
Sbjct: 1402 PTTTPSPPP---TSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPI 1458

Query: 335  LSTSSLRASMTSTPPPPVPPPP-------------PPPATALQAPAVPP--PPAPLQIAP 379
             +T++   + T +PP   P PP             PPP T    P   P  PPA     P
Sbjct: 1459 STTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLP 1518

Query: 380  GVLHPAPPPIA----PPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPP-----PPPPP 430
                P+PP       PP   PSPP     P+        LP       PP     PPP  
Sbjct: 1519 PTTTPSPPTTTTTTPPPTTTPSPPT--TTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTT 1576

Query: 431  PLPPPGIRPSSPVTVTALAHPP---------SGLHPTPSTAPGP--HVPLMPPSPPSQVI 479
               PP     SP T+T    PP         +   P P+T P P    P+ PP+  + + 
Sbjct: 1577 TPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLP 1636

Query: 480  PASEPKRHPST 490
            P + P   P+T
Sbjct: 1637 PTTTPSPPPTT 1647



 Score = 92.4 bits (228), Expect = 1e-18
 Identities = 73/231 (31%), Positives = 85/231 (36%), Gaps = 25/231 (10%)

Query: 279  PPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTS 338
            PPP          PI    S+ T      P  P T  T      TPPP   P P   +T 
Sbjct: 1533 PPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTT------TPPPTTTPSPPTTTTP 1586

Query: 339  SLRASMTSTPPPP-VPPPP------PPPATALQAPAVPP--PPAPLQIAPGVLHPAPPPI 389
            S     T+TPPP   P PP      PPP T    P   P  PP      P    P+PPP 
Sbjct: 1587 SPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPT 1646

Query: 390  A----PPLVQPSPPVAR--AAPVCETV--PVHPLPQGEVQGLPPPPPPP-PLPPPGIRPS 440
                 PP   PSPP     + P+  T   P    P   +   P PP      P P   PS
Sbjct: 1647 TTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPS 1706

Query: 441  SPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTL 491
            SP+T T      +   P P+T   P  P   PSPP+  +    P    S L
Sbjct: 1707 SPITTTTTPSSTTTPSPPPTTMTTPS-PTTTPSPPTTTMTTLPPTTTSSPL 1756



 Score = 90.1 bits (222), Expect = 5e-18
 Identities = 71/228 (31%), Positives = 82/228 (35%), Gaps = 30/228 (13%)

Query: 279  PPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTS 338
            PPP          PI    S+ T      P  P T  T      TPPP   P P   +  
Sbjct: 1494 PPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTT------TPPPTTTPSPPTTTPI 1547

Query: 339  SLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIA----PPLV 394
            +   S T+ PP   P PPP   T        PPP      P    P+PP I     PP  
Sbjct: 1548 TPPTSTTTLPPTTTPSPPPTTTTT-------PPPTTTPSPPTTTTPSPPTITTTTPPPTT 1600

Query: 395  QPSPP-VARAAPVCETVPVHP-----LPQGEVQGLPP---PPPPP---PLPPPGIRPSSP 442
             PSPP      P   T P  P      P      LPP   P PPP     PPP   PS P
Sbjct: 1601 TPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPP 1660

Query: 443  VTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPST 490
             T T      +   P P+T P   +    PSPP+  +    P   PS+
Sbjct: 1661 TTTTPSPPITTTTTPPPTTTPSSPI-TTTPSPPTTTMTTPSPTTTPSS 1707



 Score = 85.5 bits (210), Expect = 1e-16
 Identities = 64/209 (30%), Positives = 80/209 (38%), Gaps = 31/209 (14%)

Query: 292  PIPTCISSATGLIENRPQSPATGRT--PVFVSPTPPPPPPPLPSALSTSSLRASMTSTPP 349
            P+  CI++ +      P  P T  T  P   +P+PP      P   +T S   + T+TPP
Sbjct: 1391 PMDKCITTPSPPTTT-PSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPP 1449

Query: 350  PPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIA----PPLVQPSPPVARAAP 405
            P   P PP   T    P   P P     +P    P+PP       PP   PSPP      
Sbjct: 1450 PTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPT----- 1504

Query: 406  VCETVPVHPLPQGEVQGLPPPPPPPP------LPPPGIRPSSPVTVTALAHPPSGLHPTP 459
               T P+   P      LPP   P P       PPP   PS P T T +  P S     P
Sbjct: 1505 ---TTPI--TPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPP-TTTPITPPTSTTTLPP 1558

Query: 460  STAPGP-------HVPLMPPSPPSQVIPA 481
            +T P P         P   PSPP+   P+
Sbjct: 1559 TTTPSPPPTTTTTPPPTTTPSPPTTTTPS 1587



 Score = 83.6 bits (205), Expect = 4e-16
 Identities = 54/183 (29%), Positives = 72/183 (39%), Gaps = 16/183 (8%)

Query: 313  TGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPP 372
            T  +P   +P+PPP         +T S   + T+TPPP   P PP   T    P   P P
Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP 1456

Query: 373  APLQIAPGVLHPAPPPI---APPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPP 429
                  P      PPP    +PP   PSPP    +P   T    P         P PP  
Sbjct: 1457 ------PISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPP-----PTTTPSPPTT 1505

Query: 430  PPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGP--HVPLMPPSPPSQVIPASEPKRH 487
             P+ PP    + P T T      +   P P+T P P    P+ PP+  + + P + P   
Sbjct: 1506 TPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPP 1565

Query: 488  PST 490
            P+T
Sbjct: 1566 PTT 1568



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 52/181 (28%), Positives = 63/181 (34%), Gaps = 16/181 (8%)

Query: 279  PPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTS 338
            PPP          PI    S+ T      P  P T  T    + TP PP    PS   T+
Sbjct: 1612 PPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITT 1671

Query: 339  SLRASMTSTPPPPVPPPPPPPATALQAPA---VPPPPAPLQIAPG-VLHPAPPPIA---- 390
            +     T+TP  P+   P PP T +  P+    P  P      P     P+PPP      
Sbjct: 1672 TTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTP 1731

Query: 391  PPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAH 450
             P   PSPP      +  T    PL           P PP + PP   P S  T T    
Sbjct: 1732 SPTTTPSPPTTTMTTLPPTTTSSPLTT--------TPLPPSITPPTFSPFSTTTPTTPCV 1783

Query: 451  P 451
            P
Sbjct: 1784 P 1784



 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 46/151 (30%), Positives = 53/151 (35%), Gaps = 28/151 (18%)

Query: 345  TSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAA 404
            T +PP   P PPP   T L     P PP      P           PP   PSPP+    
Sbjct: 1398 TPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTP-----------PPTTTPSPPITTTT 1446

Query: 405  PVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPG 464
                T P    P        PP      PPP   PS P T  +   PP+     P+T   
Sbjct: 1447 ----TPPPTTTPS-------PPISTTTTPPPTTTPSPPTTTPS---PPTTTPSPPTTTTT 1492

Query: 465  PHVPLMPPSPPSQ---VIPASEPKRHPSTLP 492
               P   PSPP+      PAS     P+T P
Sbjct: 1493 TPPPTTTPSPPTTTPITPPASTTTLPPTTTP 1523



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 59/229 (25%), Positives = 75/229 (32%), Gaps = 29/229 (12%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 4094 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 4151

Query: 338  SSLRASMTSTPPPPVPP----PPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPL 393
            ++   + T+  P P P     P   P T        P P   Q  P   H +  PIA  L
Sbjct: 4152 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPT-HTSTAPIAE-L 4209

Query: 394  VQPSPPVARAAPVCETVPVHPLPQGE--VQGLPPP-------PPPPPL------------ 432
               +PP   + P        PL +    +  LPP        PP  P             
Sbjct: 4210 TTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLS 4269

Query: 433  PPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPA 481
            PPP    S P T T      S   PTPST          P+P     P+
Sbjct: 4270 PPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPS 4318



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 67/250 (26%), Positives = 80/250 (32%), Gaps = 46/250 (18%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATG--RTPVFVSPTPPPPPPPLPSAL 335
            P P P         PI T  +          Q+P T    T   V+PTP P     P   
Sbjct: 4048 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP--- 4104

Query: 336  STSSLRASMTSTP-PPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPI-APPL 393
            +T+ +  + T TP P P     P          V P P P     G   P   PI     
Sbjct: 4105 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP----TGTQTPTTTPITTTTT 4160

Query: 394  VQPSP-------PVARAAPVCETVPVHPLPQGEVQGLPP--------------PPPPPPL 432
            V P+P       P         TV   P P G   G P               PPP    
Sbjct: 4161 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESST 4220

Query: 433  PPPGIRPSSPVT--VTALAHPPSGLHPTPSTAPGPHVPLMP----------PSPPSQVIP 480
            P      SSP+T   T L+  P  +  T STAP P  P  P          P P +   P
Sbjct: 4221 PQTSRSTSSPLTESTTLLSTLPPAIEMT-STAP-PSTPTAPTTTSGGHTLSPPPSTTTSP 4278

Query: 481  ASEPKRHPST 490
               P R  +T
Sbjct: 4279 PGTPTRGTTT 4288



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 56/234 (23%), Positives = 75/234 (32%), Gaps = 24/234 (10%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T       + TP P P    +  +T
Sbjct: 3979 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4038

Query: 338  SSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPI-APPLVQP 396
                 +  +  P P     P          V P P P     G   P   PI     V P
Sbjct: 4039 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP----TGTQTPTTTPITTTTTVTP 4094

Query: 397  SP-----PVARAAPVCETVPVHPLPQGEVQGLPPPPP--------PPPLPPPGIRP-SSP 442
            +P           P+  T  V P P       P   P        P P P     P ++P
Sbjct: 4095 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4154

Query: 443  VTVTALAHP---PSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLPV 493
            +T T    P   P+G   TP+T P      + P+ P+     + P  H ST P+
Sbjct: 4155 ITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT-PTPTGTQTGPPTHTSTAPI 4206



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 53/201 (26%), Positives = 72/201 (35%), Gaps = 30/201 (14%)

Query: 294  PTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVP 353
            PT +++ T      P  P T  TP+  + T  P P P  +   T++   + T+  P P P
Sbjct: 1882 PTTMTTTT---TENPTPPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 1936

Query: 354  PPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPI-APPLVQPSP-----PVARAAP 405
                 P T        V P P P     G   P   PI     V P+P           P
Sbjct: 1937 TGTQTPTTTPITTTTTVTPTPTP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 1992

Query: 406  VCETVPVHPLPQGEVQGLPPPPP--------PPPLPPPGIRP-SSPVTVTALAHP---PS 453
            +  T  V P P       P   P        P P P     P ++P+T T    P   P+
Sbjct: 1993 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2052

Query: 454  GLHPTPSTAPGPHVPLMPPSP 474
            G   TP+T P      + P+P
Sbjct: 2053 GTQ-TPTTTPITTTTTVTPTP 2072



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 43/180 (23%), Positives = 56/180 (31%), Gaps = 24/180 (13%)

Query: 231  PASHFETRPQTYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDA 290
            P +   T P T       + + +  P +  S   T      +     PPP          
Sbjct: 1628 PPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITT 1687

Query: 291  KPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPP 350
             P P   +  T      P SP T  T    + TP PPP              +MT+  P 
Sbjct: 1688 TPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPP-------------TTMTTPSPT 1734

Query: 351  PVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQP---SPPVARAAPVC 407
              P PP    T L        P     +P    P PP I PP   P   + P     P+C
Sbjct: 1735 TTPSPPTTTMTTL--------PPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLC 1786



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 1909 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 1966

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 1967 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2022

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2023 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2074

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2075 TGTQ-TPTTTPITTTTTVTPTP 2095



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 1932 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 1989

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 1990 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2045

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2046 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2097

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2098 TGTQ-TPTTTPITTTTTVTPTP 2118



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 1955 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2012

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2013 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2068

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2069 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2120

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2121 TGTQ-TPTTTPITTTTTVTPTP 2141



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 1978 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2035

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2036 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2091

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2092 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2143

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2144 TGTQ-TPTTTPITTTTTVTPTP 2164



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2001 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2058

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2059 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2114

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2115 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2166

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2167 TGTQ-TPTTTPITTTTTVTPTP 2187



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2024 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2081

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2082 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2137

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2138 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2189

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2190 TGTQ-TPTTTPITTTTTVTPTP 2210



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2047 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2104

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2105 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2160

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2161 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2212

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2213 TGTQ-TPTTTPITTTTTVTPTP 2233



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2070 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2127

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2128 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2183

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2184 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2235

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2236 TGTQ-TPTTTPITTTTTVTPTP 2256



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2093 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2150

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2151 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2206

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2207 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2258

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2259 TGTQ-TPTTTPITTTTTVTPTP 2279



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2116 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2173

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2174 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2229

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2230 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2281

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2282 TGTQ-TPTTTPITTTTTVTPTP 2302



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2139 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2196

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2197 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2252

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2253 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2304

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2305 TGTQ-TPTTTPITTTTTVTPTP 2325



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2162 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2219

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2220 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2275

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2276 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2327

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2328 TGTQ-TPTTTPITTTTTVTPTP 2348



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2185 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2242

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2243 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2298

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2299 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2350

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2351 TGTQ-TPTTTPITTTTTVTPTP 2371



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2208 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2265

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2266 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2321

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2322 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2373

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2374 TGTQ-TPTTTPITTTTTVTPTP 2394



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2231 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2288

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2289 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2344

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2345 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2396

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2397 TGTQ-TPTTTPITTTTTVTPTP 2417



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2254 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2311

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2312 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2367

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2368 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2419

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2420 TGTQ-TPTTTPITTTTTVTPTP 2440



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2277 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2334

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2335 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2390

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2391 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2442

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2443 TGTQ-TPTTTPITTTTTVTPTP 2463



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2300 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2357

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2358 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2413

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2414 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2465

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2466 TGTQ-TPTTTPITTTTTVTPTP 2486



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2323 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2380

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2381 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2436

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2437 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2488

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2489 TGTQ-TPTTTPITTTTTVTPTP 2509



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2346 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2403

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2404 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2459

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2460 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2511

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2512 TGTQ-TPTTTPITTTTTVTPTP 2532



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2369 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2426

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2427 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2482

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2483 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2534

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2535 TGTQ-TPTTTPITTTTTVTPTP 2555



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2392 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2449

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2450 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2505

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2506 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2557

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2558 TGTQ-TPTTTPITTTTTVTPTP 2578



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2415 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2472

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2473 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2528

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2529 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2580

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2581 TGTQ-TPTTTPITTTTTVTPTP 2601



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2438 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2495

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2496 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2551

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2552 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2603

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2604 TGTQ-TPTTTPITTTTTVTPTP 2624



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2461 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2518

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2519 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2574

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2575 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2626

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2627 TGTQ-TPTTTPITTTTTVTPTP 2647



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2484 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2541

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2542 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2597

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2598 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2649

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2650 TGTQ-TPTTTPITTTTTVTPTP 2670



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2507 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2564

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2565 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2620

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2621 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2672

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2673 TGTQ-TPTTTPITTTTTVTPTP 2693



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2530 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2587

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2588 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2643

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2644 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2695

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2696 TGTQ-TPTTTPITTTTTVTPTP 2716



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2553 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2610

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2611 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2666

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2667 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2718

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2719 TGTQ-TPTTTPITTTTTVTPTP 2739



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2576 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2633

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2634 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2689

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2690 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2741

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2742 TGTQ-TPTTTPITTTTTVTPTP 2762



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2599 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2656

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2657 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2712

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2713 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2764

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2765 TGTQ-TPTTTPITTTTTVTPTP 2785



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2622 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2679

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2680 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2735

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2736 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2787

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2788 TGTQ-TPTTTPITTTTTVTPTP 2808



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2645 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2702

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2703 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2758

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2759 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2810

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2811 TGTQ-TPTTTPITTTTTVTPTP 2831



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2668 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2725

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2726 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2781

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2782 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2833

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2834 TGTQ-TPTTTPITTTTTVTPTP 2854



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2691 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2748

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2749 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2804

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2805 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2856

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2857 TGTQ-TPTTTPITTTTTVTPTP 2877



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2714 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2771

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2772 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2827

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2828 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2879

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2880 TGTQ-TPTTTPITTTTTVTPTP 2900



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2737 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2794

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2795 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2850

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2851 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2902

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2903 TGTQ-TPTTTPITTTTTVTPTP 2923



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2760 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2817

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2818 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2873

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2874 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2925

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2926 TGTQ-TPTTTPITTTTTVTPTP 2946



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2783 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2840

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2841 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2896

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2897 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2948

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2949 TGTQ-TPTTTPITTTTTVTPTP 2969



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2806 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2863

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2864 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2919

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2920 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2971

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2972 TGTQ-TPTTTPITTTTTVTPTP 2992



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2829 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2886

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2887 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2942

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2943 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 2994

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 2995 TGTQ-TPTTTPITTTTTVTPTP 3015



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2852 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2909

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2910 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2965

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2966 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3017

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3018 TGTQ-TPTTTPITTTTTVTPTP 3038



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2875 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2932

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2933 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 2988

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 2989 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3040

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3041 TGTQ-TPTTTPITTTTTVTPTP 3061



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2898 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2955

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2956 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3011

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3012 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3063

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3064 TGTQ-TPTTTPITTTTTVTPTP 3084



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2921 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 2978

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 2979 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3034

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3035 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3086

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3087 TGTQ-TPTTTPITTTTTVTPTP 3107



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2944 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3001

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3002 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3057

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3058 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3109

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3110 TGTQ-TPTTTPITTTTTVTPTP 3130



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2967 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3024

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3025 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3080

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3081 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3132

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3133 TGTQ-TPTTTPITTTTTVTPTP 3153



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 2990 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3047

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3048 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3103

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3104 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3155

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3156 TGTQ-TPTTTPITTTTTVTPTP 3176



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3013 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3070

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3071 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3126

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3127 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3178

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3179 TGTQ-TPTTTPITTTTTVTPTP 3199



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3036 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3093

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3094 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3149

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3150 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3201

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3202 TGTQ-TPTTTPITTTTTVTPTP 3222



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3059 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3116

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3117 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3172

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3173 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3224

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3225 TGTQ-TPTTTPITTTTTVTPTP 3245



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3082 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3139

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3140 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3195

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3196 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3247

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3248 TGTQ-TPTTTPITTTTTVTPTP 3268



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3105 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3162

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3163 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3218

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3219 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3270

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3271 TGTQ-TPTTTPITTTTTVTPTP 3291



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3128 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3185

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3186 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3241

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3242 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3293

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3294 TGTQ-TPTTTPITTTTTVTPTP 3314



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3151 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3208

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3209 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3264

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3265 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3316

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3317 TGTQ-TPTTTPITTTTTVTPTP 3337



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3174 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3231

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3232 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3287

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3288 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3339

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3340 TGTQ-TPTTTPITTTTTVTPTP 3360



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3197 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3254

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3255 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3310

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3311 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3362

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3363 TGTQ-TPTTTPITTTTTVTPTP 3383



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3220 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3277

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3278 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3333

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3334 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3385

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3386 TGTQ-TPTTTPITTTTTVTPTP 3406



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3243 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3300

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3301 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3356

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3357 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3408

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3409 TGTQ-TPTTTPITTTTTVTPTP 3429



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3266 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3323

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3324 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3379

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3380 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3431

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3432 TGTQ-TPTTTPITTTTTVTPTP 3452



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3289 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3346

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3347 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3402

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3403 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3454

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3455 TGTQ-TPTTTPITTTTTVTPTP 3475



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3312 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3369

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3370 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3425

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3426 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3477

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3478 TGTQ-TPTTTPITTTTTVTPTP 3498



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3335 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3392

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3393 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3448

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3449 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3500

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3501 TGTQ-TPTTTPITTTTTVTPTP 3521



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3358 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3415

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3416 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3471

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3472 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3523

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3524 TGTQ-TPTTTPITTTTTVTPTP 3544



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3381 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3438

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3439 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3494

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3495 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3546

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3547 TGTQ-TPTTTPITTTTTVTPTP 3567



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3404 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3461

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3462 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3517

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3518 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3569

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3570 TGTQ-TPTTTPITTTTTVTPTP 3590



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3427 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3484

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3485 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3540

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3541 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3592

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3593 TGTQ-TPTTTPITTTTTVTPTP 3613



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3450 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3507

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3508 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3563

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3564 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3615

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3616 TGTQ-TPTTTPITTTTTVTPTP 3636



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3473 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3530

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3531 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3586

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3587 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3638

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3639 TGTQ-TPTTTPITTTTTVTPTP 3659



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3496 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3553

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3554 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3609

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3610 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3661

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3662 TGTQ-TPTTTPITTTTTVTPTP 3682



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3519 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3576

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3577 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3632

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3633 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3684

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3685 TGTQ-TPTTTPITTTTTVTPTP 3705



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3542 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3599

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3600 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3655

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3656 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3707

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3708 TGTQ-TPTTTPITTTTTVTPTP 3728



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3565 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3622

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3623 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3678

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3679 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3730

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3731 TGTQ-TPTTTPITTTTTVTPTP 3751



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3588 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3645

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3646 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3701

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3702 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3753

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3754 TGTQ-TPTTTPITTTTTVTPTP 3774



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3611 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3668

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3669 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3724

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3725 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3776

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3777 TGTQ-TPTTTPITTTTTVTPTP 3797



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3634 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3691

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3692 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3747

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3748 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3799

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3800 TGTQ-TPTTTPITTTTTVTPTP 3820



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3657 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3714

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3715 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3770

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3771 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3822

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3823 TGTQ-TPTTTPITTTTTVTPTP 3843



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3680 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3737

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3738 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3793

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3794 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3845

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3846 TGTQ-TPTTTPITTTTTVTPTP 3866



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3703 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3760

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3761 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3816

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3817 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3868

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3869 TGTQ-TPTTTPITTTTTVTPTP 3889



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3726 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3783

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3784 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3839

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3840 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3891

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3892 TGTQ-TPTTTPITTTTTVTPTP 3912



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3749 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3806

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3807 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3862

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3863 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3914

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3915 TGTQ-TPTTTPITTTTTVTPTP 3935



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3772 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3829

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3830 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3885

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3886 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3937

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3938 TGTQ-TPTTTPITTTTTVTPTP 3958



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3795 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3852

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3853 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3908

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3909 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3960

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3961 TGTQ-TPTTTPITTTTTVTPTP 3981



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/202 (24%), Positives = 66/202 (32%), Gaps = 20/202 (9%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T  TP+  + T  P P P  +   T
Sbjct: 3818 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPT 3875

Query: 338  SSLRASMTSTPPPPVPPPPPPPATA--LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++   + T+  P P P     P T        V P P P     G   P   PI      
Sbjct: 3876 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTTTPITTTTTV 3931

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP---P 452
               P         T P+           P P P     P     ++P+T T    P   P
Sbjct: 3932 TPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTP 3983

Query: 453  SGLHPTPSTAPGPHVPLMPPSP 474
            +G   TP+T P      + P+P
Sbjct: 3984 TGTQ-TPTTTPITTTTTVTPTP 4004



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 51/215 (23%), Positives = 67/215 (31%), Gaps = 23/215 (10%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P P P         PI T  +          Q+P T       + TP P P    +  +T
Sbjct: 3864 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3923

Query: 338  SSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPI-APPLVQP 396
                 +  +  P P     P          V P P P     G   P   PI     V P
Sbjct: 3924 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP----TGTQTPTTTPITTTTTVTP 3979

Query: 397  SP-----PVARAAPVCETVPVHPLPQGEVQGLPPPPP--------PPPLPPPGIRP-SSP 442
            +P           P+  T  V P P       P   P        P P P     P ++P
Sbjct: 3980 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4039

Query: 443  VTVTALAHP---PSGLHPTPSTAPGPHVPLMPPSP 474
            +T T    P   P+G   TP+T P      + P+P
Sbjct: 4040 ITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTP 4073



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 58/262 (22%), Positives = 78/262 (29%), Gaps = 61/262 (23%)

Query: 277  EPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALS 336
            + P   P+       P PT   + TG   +   +P    T    S  PP    P  S  +
Sbjct: 4171 QTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELT---TSNPPPESSTPQTSRST 4227

Query: 337  TSSLRASMT--STPPPPV-------PPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPP 387
            +S L  S T  ST PP +       P  P  P T      + PPP+     PG      P
Sbjct: 4228 SSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGT-----P 4282

Query: 388  PIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRP-SSPVTVT 446
                     S P         T    P P        P   P  +   G+RP  S V + 
Sbjct: 4283 TRGTTTGSSSAPTPSTVQTTTTSAWTPTP-------TPLSTPSIIRTTGLRPYPSSVLIC 4335

Query: 447  ALAHP------------------------------------PSGLHPTPSTAPGPHVPLM 470
             + +                                     PS   PTP+ +     P  
Sbjct: 4336 CVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSK 4395

Query: 471  PPSPPSQVIPASEPKRHPSTLP 492
            P S PS+  P ++P   P   P
Sbjct: 4396 PSSTPSKPTPGTKPPECPDFDP 4417


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 93.2 bits (230), Expect = 6e-19
 Identities = 78/226 (34%), Positives = 91/226 (40%), Gaps = 54/226 (23%)

Query: 298 SSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSAL-STSSLRASMTS---------- 346
           S A G     P  P     P    PTPPPPPPPLP  L S+S ++  + S          
Sbjct: 156 SEAHGAARTAPPRPNVPAPP---PPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNL 212

Query: 347 ---------TPPPPVPPPPP-----PPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPP 392
                     PPPP PPPPP     PPA+ L   AV P     Q+AP  L P PPP+  P
Sbjct: 213 PVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKP-----QLAPLHLPPIPPPL--P 265

Query: 393 LVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPP----------PLPP-PGIRPSS 441
           L+ P        P  +  P  P    +    PPPP PP          P PP PG+  SS
Sbjct: 266 LLPPC-----GYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSS 320

Query: 442 PVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRH 487
                     PS   P P  A    +P  P  P SQ  P  + KRH
Sbjct: 321 ETPPPLPPKSPSFQAP-PQKAGAQALPAPPAPPGSQ--PFLQKKRH 363



 Score = 88.6 bits (218), Expect = 1e-17
 Identities = 77/228 (33%), Positives = 91/228 (39%), Gaps = 47/228 (20%)

Query: 275 PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPAT-GRTPVFVSPTP-------PP 326
           P  PPPPPP+       P+P+     T L+   P  P T G  PV   P P       PP
Sbjct: 177 PTPPPPPPPL-----PPPLPSSSPIKTPLVS--PPGPLTKGNLPVVAPPVPCAPPPPPPP 229

Query: 327 P---PPPLP--SALSTSSLRASMTSTPPPPVPPPPP--PPATALQAPAVPPPPAPLQIAP 379
           P   PPPLP  S LS  +++  +     PP+PPP P  PP       A P  PA     P
Sbjct: 230 PPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEP 289

Query: 380 GVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRP 439
               PAPPP  PP    SP  +  AP        PLP G       PPP PP  P    P
Sbjct: 290 ----PAPPPPLPPYASCSPRASLPAP--------PLP-GVNSSSETPPPLPPKSPSFQAP 336

Query: 440 SSPVTVTALAHPPS----------GLHPTPSTAPGPHVPLMPPSPPSQ 477
                  AL  PP+            H  P    G   P  PP+PP++
Sbjct: 337 PQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNP--PPAPPAR 382



 Score = 66.6 bits (161), Expect = 6e-11
 Identities = 76/266 (28%), Positives = 96/266 (36%), Gaps = 60/266 (22%)

Query: 275 PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVF-----------VSPT 323
           P  PPPPPP+       P    +S+ T  +    ++   GR+ +            V+  
Sbjct: 9   PPLPPPPPPLGAPPPPPPSAPPVSTDTSSLR---RADPKGRSALLADIQQGTRLRKVTQI 65

Query: 324 PPPPPPPLPSALSTS-----SLRASMTSTPP----------PPVPPPPPPPATALQAPAV 368
                P + S+  T+     S      STPP          P + P         +    
Sbjct: 66  NDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQG 125

Query: 369 PPPPAPLQIAPG--VLHPAPPPIAPPLVQPSPP--VARAAPVCETVPVHPLPQGEVQGLP 424
           P   AP    P   +  P  PP +P L   S     AR AP    VP  P P        
Sbjct: 126 PGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPT------- 178

Query: 425 PPPPPPPLPPPGIRPSSPVTVTALAHPPSGLH--------------PTPSTAPGPHVPLM 470
           PPPPPPPLPPP   PSS    T L  PP  L               P P   P P  P  
Sbjct: 179 PPPPPPPLPPP--LPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTP-- 234

Query: 471 PPSPPSQVI--PASEPKRHPSTLPVI 494
           PP PP+ V+   A +P+  P  LP I
Sbjct: 235 PPLPPASVLSDKAVKPQLAPLHLPPI 260



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 78/277 (28%), Positives = 86/277 (31%), Gaps = 100/277 (36%)

Query: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
           PPPPPP        P+P             P  P  G      +P PPPP  P P +  T
Sbjct: 4   PPPPPP--------PLP-------------PPPPPLG------APPPPPPSAP-PVSTDT 35

Query: 338 SSLRAS--------------------MTSTPPPPVP--------------------PPPP 357
           SSLR +                    +T       P                       P
Sbjct: 36  SSLRRADPKGRSALLADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTP 95

Query: 358 PPATALQAPAVP--PPPAPLQIAPGVLHPAPPPIAP-----------PLVQPSPP----- 399
           P    L A   P   P     +A G     P   AP           PL+ P+ P     
Sbjct: 96  PTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNT 155

Query: 400 -----VARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSG 454
                 AR AP    VP  P P        PPPPPPPLPPP   PSS    T L  PP  
Sbjct: 156 SEAHGAARTAPPRPNVPAPPPP-------TPPPPPPPLPPP--LPSSSPIKTPLVSPPGP 206

Query: 455 LHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTL 491
           L         P VP  PP PP    P   P    S L
Sbjct: 207 LTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVL 243



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 55/166 (33%), Positives = 65/166 (39%), Gaps = 40/166 (24%)

Query: 256 PFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGR 315
           P    S L  +A +  L   H PP PPP+        +P C     GL +  P SPA   
Sbjct: 236 PLPPASVLSDKAVKPQLAPLHLPPIPPPL------PLLPPC--GYPGL-KAEPASPAQD- 285

Query: 316 TPVFVSPTPPPPPPPLPSALSTSSLRASMTSTP----------PPPVPPP------PPPP 359
                +  PP PPPPLP   S S  RAS+ + P          PPP+PP       PP  
Sbjct: 286 -----AQEPPAPPPPLPPYASCSP-RASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQK 339

Query: 360 ATALQAPAVPPPPAPLQIAPGVLHPAP--------PPIAPPLVQPS 397
           A A   PA P PP          H  P        PP APP   P+
Sbjct: 340 AGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPT 385



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 60/214 (28%), Positives = 74/214 (34%), Gaps = 82/214 (38%)

Query: 351 PVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETV 410
           PVPPPPPPP        +PPPP PL  AP    P PPP APP+   +  + RA P   + 
Sbjct: 2   PVPPPPPPP--------LPPPPPPLG-AP----PPPPPSAPPVSTDTSSLRRADPKGRSA 48

Query: 411 PVHPLPQG-------------------------------EVQGLPPPPPP--------PP 431
            +  + QG                                 +G   PP          P 
Sbjct: 49  LLADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPV 108

Query: 432 LPP--------------PGIRPSSP----VTVTALAHPP--------SGLHPTPSTA-PG 464
           L P              PG R  SP     T++    PP        S  H    TA P 
Sbjct: 109 LRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPR 168

Query: 465 PHVPLMP---PSPPSQVIPASEPKRHPSTLPVIS 495
           P+VP  P   P PP   +P   P   P   P++S
Sbjct: 169 PNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVS 202



 Score = 36.6 bits (83), Expect = 0.062
 Identities = 25/70 (35%), Positives = 33/70 (47%), Gaps = 13/70 (18%)

Query: 463 PGPHVPLMPPSPPSQVIPASEPKRHPSTLPVISD----------ARSVLLEAIRKGIQLR 512
           P P  P +PP PP    P   P   PS  PV +D           RS LL  I++G +LR
Sbjct: 4   PPPPPPPLPPPPPPLGAPPPPP---PSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLR 60

Query: 513 KVEEQREQEA 522
           KV +  ++ A
Sbjct: 61  KVTQINDRSA 70


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 92.4 bits (228), Expect = 1e-18
 Identities = 78/251 (31%), Positives = 104/251 (41%), Gaps = 46/251 (18%)

Query: 253 SALPFSQMSELLTRAEERVLVRPHEPPPP---PPMHGAGDAKPIPTCISSATGLIENRPQ 309
           S LP   +S L T         P + PP    PP+     A P P      + L    PQ
Sbjct: 379 SFLPSPPLSPLATP--------PPQAPPALALPPLQ----APPSPPASPPLSPLATPSPQ 426

Query: 310 SPATGRTPVFVSPTPPPPPPPLPSALST-SSLRASMTSTPPPPVPP---------PPPPP 359
           +P      +  +P  PPP PP+ +  S  +S   S ++TPP   PP         PP PP
Sbjct: 427 APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 486

Query: 360 ATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGE 419
           A+   +P+  PPP            APPP+A P +Q + P  +A P   T P        
Sbjct: 487 ASPPMSPSATPPP-----------QAPPPLAAPPLQLAKPPPQAPPALATPP-------- 527

Query: 420 VQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVI 479
           +Q LP PP   P   P   PS+ + ++ LA PP    P    AP   VP  PP+ P+   
Sbjct: 528 LQALPSPPASFPGQAP-FSPSASLPMSPLATPPPQAPPV-LAAPLLQVPPSPPASPTLQA 585

Query: 480 PASEPKRHPST 490
           P   P   P T
Sbjct: 586 PRRPPTPGPDT 596



 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 86/261 (32%), Positives = 108/261 (41%), Gaps = 32/261 (12%)

Query: 251 SLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQS 310
           +L A P S  S L  +    + + P  P  PP +       P  T  S AT  +     S
Sbjct: 320 TLPATPHS--SSLTCQLATPLPLAPPSPSAPPSLQTL--PSPPATPPSQATTSLG----S 371

Query: 311 PATGRTPVFVSPTPP-----PPPPPLPSALSTSSLRASMTSTPPPPVPP-----PPPPPA 360
           P    T  F+ P+PP      PPP  P AL+   L+A  +    PP+ P     P  P A
Sbjct: 372 PTLQATHSFL-PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNA 430

Query: 361 TA---LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSP-PVARAAPVCETVPVHPL- 415
            A   LQAP  PPP  P+Q AP    PA PP++P    PS  P + AAP  +  P  P  
Sbjct: 431 LAVHLLQAPFSPPPSPPVQ-AP-FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 488

Query: 416 PQGEVQGLPPP--PPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPS 473
           P       PPP  PPP   PP  +    P    ALA PP    P+P  +     P   P 
Sbjct: 489 PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPAS----FPGQAPF 544

Query: 474 PPSQVIPASEPKRHPSTLPVI 494
            PS  +P S     P   P +
Sbjct: 545 SPSASLPMSPLATPPPQAPPV 565



 Score = 82.8 bits (203), Expect = 8e-16
 Identities = 74/253 (29%), Positives = 100/253 (39%), Gaps = 45/253 (17%)

Query: 273 VRPHEPPPP----PPMHGAGDAKPIPTCISSATGLIENRPQSPATGR---------TPVF 319
           +RP +  PP     P  G   + P+ T   SA    +  P  PAT           TP+ 
Sbjct: 280 LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLP 339

Query: 320 VSPTPP---------PPPPPLPSALSTSSL--------RASMTSTPPPPVPPPPPPPATA 362
           ++P  P         P PP  P + +T+SL         + + S P  P+  PPP    A
Sbjct: 340 LAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA 399

Query: 363 LQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPV-CETVPVHPLPQGEVQ 421
           L  P +  PP+P         PA PP++ PL  PSP    A  V     P  P P   VQ
Sbjct: 400 LALPPLQAPPSP---------PASPPLS-PLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 449

Query: 422 GLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAP--GPHVPLMPPSPPSQVI 479
               PP  PP+ P    PS      +LA PP  + P+P  +P   P     P +PP    
Sbjct: 450 APFSPPASPPVSPSATPPSQ--APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA 507

Query: 480 PASEPKRHPSTLP 492
           P  +  + P   P
Sbjct: 508 PPLQLAKPPPQAP 520



 Score = 76.6 bits (187), Expect = 5e-14
 Identities = 68/210 (32%), Positives = 78/210 (37%), Gaps = 42/210 (20%)

Query: 271 VLVRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPP 330
           +L  P  PPP PP+         P    SAT   +  P   A    P+ V P+PP  PP 
Sbjct: 435 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP---PLQVPPSPPASPPM 491

Query: 331 LPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPA----PLQIAPG--VLHP 384
            PSA            TPPP  PPP   P   L  P    PPA    PLQ  P      P
Sbjct: 492 SPSA------------TPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP 539

Query: 385 APPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPP-----------PPPLP 433
              P +P    P  P+A   P    V   PL Q     +PP PP           P P P
Sbjct: 540 GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ-----VPPSPPASPTLQAPRRPPTPGP 594

Query: 434 PPGIRPSSPVTVTALAHPPSGLHPTPSTAP 463
              +  S P    ALA  P    P PS +P
Sbjct: 595 DTSV--SGPRLTLALAPGPP---PPPSRSP 619



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 65/248 (26%), Positives = 85/248 (34%), Gaps = 44/248 (17%)

Query: 251 SLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPI--PTCISSATGLIENRP 308
           S SA P SQ    L     +V   P  PP  PPM  +    P   P   +    L +  P
Sbjct: 461 SPSATPPSQAPPSLAAPPLQV---PPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 517

Query: 309 QSP-ATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPP------------- 354
           Q+P A    P+   P+PP   P       ++SL  S  +TPPP  PP             
Sbjct: 518 QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 577

Query: 355 ------------PPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVAR 402
                       P P P T++  P +      L +APG   P PP  +P      P +A 
Sbjct: 578 PASPTLQAPRRPPTPGPDTSVSGPRL-----TLALAPG--PPPPPSRSPSSTLSGPDLAG 630

Query: 403 AAPVCETVP-----VHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHP 457
            +    + P         P+G     PPP        P      P    A    P    P
Sbjct: 631 HSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLP 690

Query: 458 -TPSTAPG 464
             P+T PG
Sbjct: 691 WPPATGPG 698



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 56/198 (28%), Positives = 75/198 (37%), Gaps = 31/198 (15%)

Query: 322 PTPPPPPPPLPSALSTSSL-----RASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQ 376
           PTP  P P +      +       R + ++ P PP   P    ++A +     P PA  +
Sbjct: 167 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226

Query: 377 ---IAPGVLHPAPPPI---APPLVQP--SPPVARAAPVCETVPVHPLPQGEVQGLPPPPP 428
                 G+  PA   +   A PL  P  S P AR  P     P  P P+G +Q L PP  
Sbjct: 227 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG-LQALRPPQV 285

Query: 429 PPP----LPPPGIRPSSPV-----TVTALAHPPSGLHPTPSTA--------PGPHVPLMP 471
            PP     P  G   SSP+     +    +  P  L  TP ++        P P  P  P
Sbjct: 286 TPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSP 345

Query: 472 PSPPSQVIPASEPKRHPS 489
            +PPS     S P   PS
Sbjct: 346 SAPPSLQTLPSPPATPPS 363



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 54/218 (24%), Positives = 75/218 (34%), Gaps = 40/218 (18%)

Query: 309 QSPATGRTPVFVSPTPP----PPPPPLPSALSTSSLRASMTSTP---------------P 349
           ++PA  R P  ++P PP    PPPP  P+AL       ++   P                
Sbjct: 15  RTPAA-RAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES 73

Query: 350 PPVPPPPPPPATALQAPAVPPPPAPL-QIAPGVLHPAPPPIAPP-----LVQPSP----- 398
            P   P     T+ + PA  PP +   + AP   + +P P++ P       +P P     
Sbjct: 74  APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 133

Query: 399 -------PVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHP 451
                   VAR     E      L  G  +    P P  P P    R  +  T   L  P
Sbjct: 134 LRISAEETVAR-GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 192

Query: 452 PSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPS 489
                P P T  GP   +   S  S   P+   +R PS
Sbjct: 193 APSARPRPPT-EGPRKSVSSASEHSTTEPSPAARRRPS 229



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 46/170 (27%), Positives = 56/170 (32%), Gaps = 59/170 (34%)

Query: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATG------RTPVFVSPTPPPPPPPL 331
           PP  PP+  A   +  P+  +S T     RP +P         R  + ++P PPPPP   
Sbjct: 559 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 618

Query: 332 PSA-LSTSSLR---ASMTSTPPP-------------PVPPP---------------PPPP 359
           PS+ LS   L    +S TSTP                 PPP               P PP
Sbjct: 619 PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPP 678

Query: 360 ATALQAPAVPPP---------------------PAPLQIAPGVLHPAPPP 388
                AP  P P                     P     APG L P P P
Sbjct: 679 LAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 728



 Score = 37.7 bits (86), Expect = 0.028
 Identities = 56/200 (28%), Positives = 71/200 (35%), Gaps = 51/200 (25%)

Query: 333 SALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPA----PLQIAPGVLHPAPPP 388
           +A  T + RA    TP PP  P PPPP T      +    A    PL    G +  A  P
Sbjct: 12  AAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71

Query: 389 IAPPLVQPS-------------PPVA----RAAPVCETVPVHPLPQGEVQGLPPPPPPPP 431
            + P   P+             PP +    RA P   T P      G   G      P P
Sbjct: 72  ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASG---TTRPGP 128

Query: 432 LPPPGIRPSSPVTV-----------TALA----HPPSGLHPTPST----------APGPH 466
           L   G+R S+  TV           +AL+       SG  PTP T          A G  
Sbjct: 129 LGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG--PTPGTPSPAMARRSRAAGTE 186

Query: 467 VPLMPPSPPSQVIPASEPKR 486
           V L  P+P ++  P +E  R
Sbjct: 187 VGLPRPAPSARPRPPTEGPR 206


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 92.4 bits (228), Expect = 1e-18
 Identities = 78/251 (31%), Positives = 104/251 (41%), Gaps = 46/251 (18%)

Query: 253 SALPFSQMSELLTRAEERVLVRPHEPPPP---PPMHGAGDAKPIPTCISSATGLIENRPQ 309
           S LP   +S L T         P + PP    PP+     A P P      + L    PQ
Sbjct: 340 SFLPSPPLSPLATP--------PPQAPPALALPPLQ----APPSPPASPPLSPLATPSPQ 387

Query: 310 SPATGRTPVFVSPTPPPPPPPLPSALST-SSLRASMTSTPPPPVPP---------PPPPP 359
           +P      +  +P  PPP PP+ +  S  +S   S ++TPP   PP         PP PP
Sbjct: 388 APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 447

Query: 360 ATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGE 419
           A+   +P+  PPP            APPP+A P +Q + P  +A P   T P        
Sbjct: 448 ASPPMSPSATPPP-----------QAPPPLAAPPLQLAKPPPQAPPALATPP-------- 488

Query: 420 VQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVI 479
           +Q LP PP   P   P   PS+ + ++ LA PP    P    AP   VP  PP+ P+   
Sbjct: 489 LQALPSPPASFPGQAP-FSPSASLPMSPLATPPPQAPPV-LAAPLLQVPPSPPASPTLQA 546

Query: 480 PASEPKRHPST 490
           P   P   P T
Sbjct: 547 PRRPPTPGPDT 557



 Score = 84.3 bits (207), Expect = 3e-16
 Identities = 80/239 (33%), Positives = 98/239 (41%), Gaps = 31/239 (12%)

Query: 275 PHEPPPP--PPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPP-----PP 327
           P  PP P  PP      + P      + T L      SP    T  F+ P+PP      P
Sbjct: 300 PSAPPSPSAPPSLQTLPSPPATPPSQATTSL-----GSPTLQATHSFL-PSPPLSPLATP 353

Query: 328 PPPLPSALSTSSLRASMTSTPPPPVPP-----PPPPPATA---LQAPAVPPPPAPLQIAP 379
           PP  P AL+   L+A  +    PP+ P     P  P A A   LQAP  PPP  P+Q AP
Sbjct: 354 PPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ-AP 412

Query: 380 GVLHPAPPPIAPPLVQPSP-PVARAAPVCETVPVHPL-PQGEVQGLPPP--PPPPPLPPP 435
               PA PP++P    PS  P + AAP  +  P  P  P       PPP  PPP   PP 
Sbjct: 413 -FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 471

Query: 436 GIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLPVI 494
            +    P    ALA PP    P+P  +     P   P  PS  +P S     P   P +
Sbjct: 472 QLAKPPPQAPPALATPPLQALPSPPAS----FPGQAPFSPSASLPMSPLATPPPQAPPV 526



 Score = 83.6 bits (205), Expect = 4e-16
 Identities = 84/268 (31%), Positives = 106/268 (39%), Gaps = 42/268 (15%)

Query: 249 SYSLSALPFSQ--MSELLTRAEERVLVRPHEPPP--------PPPMHGAGDAKPIPTCIS 298
           S S SA P S    S    R   R    P +P P        P       DA P    +S
Sbjct: 232 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 291

Query: 299 SATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTS----SLRASMTSTPPPPVPP 354
           S+  L    P +P +   P  +   P PP  P PS  +TS    +L+A+ +  P PP+ P
Sbjct: 292 SSP-LATPSPSAPPSPSAPPSLQTLPSPPATP-PSQATTSLGSPTLQATHSFLPSPPLSP 349

Query: 355 ---PPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPV-CETV 410
              PPP    AL  P +  PP+P         PA PP++P L  PSP    A  V     
Sbjct: 350 LATPPPQAPPALALPPLQAPPSP---------PASPPLSP-LATPSPQAPNALAVHLLQA 399

Query: 411 PVHPLPQGEVQG--LPPPPPP--PPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAP--G 464
           P  P P   VQ    PP  PP  P   PP   P S      LA PP  + P+P  +P   
Sbjct: 400 PFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS------LAAPPLQVPPSPPASPPMS 453

Query: 465 PHVPLMPPSPPSQVIPASEPKRHPSTLP 492
           P     P +PP    P  +  + P   P
Sbjct: 454 PSATPPPQAPPPLAAPPLQLAKPPPQAP 481



 Score = 76.6 bits (187), Expect = 5e-14
 Identities = 68/210 (32%), Positives = 78/210 (37%), Gaps = 42/210 (20%)

Query: 271 VLVRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPP 330
           +L  P  PPP PP+         P    SAT   +  P   A    P+ V P+PP  PP 
Sbjct: 396 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP---PLQVPPSPPASPPM 452

Query: 331 LPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPA----PLQIAPG--VLHP 384
            PSA            TPPP  PPP   P   L  P    PPA    PLQ  P      P
Sbjct: 453 SPSA------------TPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP 500

Query: 385 APPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPP-----------PPPLP 433
              P +P    P  P+A   P    V   PL Q     +PP PP           P P P
Sbjct: 501 GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ-----VPPSPPASPTLQAPRRPPTPGP 555

Query: 434 PPGIRPSSPVTVTALAHPPSGLHPTPSTAP 463
              +  S P    ALA  P    P PS +P
Sbjct: 556 DTSV--SGPRLTLALAPGPP---PPPSRSP 580



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 65/248 (26%), Positives = 85/248 (34%), Gaps = 44/248 (17%)

Query: 251 SLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPI--PTCISSATGLIENRP 308
           S SA P SQ    L     +V   P  PP  PPM  +    P   P   +    L +  P
Sbjct: 422 SPSATPPSQAPPSLAAPPLQV---PPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 478

Query: 309 QSP-ATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPP------------- 354
           Q+P A    P+   P+PP   P       ++SL  S  +TPPP  PP             
Sbjct: 479 QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 538

Query: 355 ------------PPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVAR 402
                       P P P T++  P +      L +APG   P PP  +P      P +A 
Sbjct: 539 PASPTLQAPRRPPTPGPDTSVSGPRL-----TLALAPG--PPPPPSRSPSSTLSGPDLAG 591

Query: 403 AAPVCETVP-----VHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHP 457
            +    + P         P+G     PPP        P      P    A    P    P
Sbjct: 592 HSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLP 651

Query: 458 -TPSTAPG 464
             P+T PG
Sbjct: 652 WPPATGPG 659



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 58/204 (28%), Positives = 75/204 (36%), Gaps = 35/204 (17%)

Query: 322 PTPPP---PPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPA-------VPPP 371
           P P P   P PP      + S  +  ++T P P     P     LQ PA         P 
Sbjct: 181 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 240

Query: 372 PAPLQIAPGV-------LHPAPP------PIAPPLVQPSPPVARAAPVCETVPVHPLPQG 418
            +P +  P          HP+ P       + PP  Q +PP   AAP    +   PL   
Sbjct: 241 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP--QVTPPRKDAAPALGPLSSSPLATP 298

Query: 419 EVQGLPPPPPPP---PLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHV-PLM---P 471
                P P  PP    LP P   P S  T T+L  P   L  T S  P P + PL    P
Sbjct: 299 SPSAPPSPSAPPSLQTLPSPPATPPSQAT-TSLGSPT--LQATHSFLPSPPLSPLATPPP 355

Query: 472 PSPPSQVIPASEPKRHPSTLPVIS 495
            +PP+  +P  +    P   P +S
Sbjct: 356 QAPPALALPPLQAPPSPPASPPLS 379



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 54/209 (25%), Positives = 69/209 (33%), Gaps = 31/209 (14%)

Query: 309 QSPATGRTPVFVSPTPP----PPPPPLPSALSTSSLRASMTSTP-------------PPP 351
           ++PA  R P  ++P PP    PPPP  P+AL       ++   P             P  
Sbjct: 15  RTPAA-RAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES 73

Query: 352 VPPPPP-----PPATA---LQAPAVPPPPAPLQI---APGVLHPAPPPIAPPLVQPSPPV 400
            P   P     PPA+       PA    P P+     A G   P P       +     V
Sbjct: 74  APRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV 133

Query: 401 ARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPS 460
           AR     E      L  G  +    P P  P P    R  +  T   L  P     P P 
Sbjct: 134 AR-GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 192

Query: 461 TAPGPHVPLMPPSPPSQVIPASEPKRHPS 489
           T  GP   +   S  S   P+   +R PS
Sbjct: 193 T-EGPRKSVSSASEHSTTEPSPAARRRPS 220



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 59/191 (30%), Positives = 72/191 (37%), Gaps = 42/191 (21%)

Query: 333 SALSTSSLRASMTSTPPPPVPPPPPPPAT--ALQ----APAVPPPPAPLQIA--PGVLHP 384
           +A  T + RA    TP PP  P PPPP T  AL+    A AV   P   +     G   P
Sbjct: 12  AAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71

Query: 385 APPPIAPPLVQPSPPVA----RAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPS 440
              P A P     PP +    RA P   T P      G   G      P PL   G+R S
Sbjct: 72  ESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASG---TTRPGPLGQKGLRIS 128

Query: 441 SPVTV-----------TALA----HPPSGLHPTPST----------APGPHVPLMPPSPP 475
           +  TV           +AL+       SG  PTP T          A G  V L  P+P 
Sbjct: 129 AEETVARGKATEAPKRSALSAGARRDTSG--PTPGTPSPAMARRSRAAGTEVGLPRPAPS 186

Query: 476 SQVIPASEPKR 486
           ++  P +E  R
Sbjct: 187 ARPRPPTEGPR 197



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 46/170 (27%), Positives = 56/170 (32%), Gaps = 59/170 (34%)

Query: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATG------RTPVFVSPTPPPPPPPL 331
           PP  PP+  A   +  P+  +S T     RP +P         R  + ++P PPPPP   
Sbjct: 520 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 579

Query: 332 PSA-LSTSSLR---ASMTSTPPP-------------PVPPP---------------PPPP 359
           PS+ LS   L    +S TSTP                 PPP               P PP
Sbjct: 580 PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPP 639

Query: 360 ATALQAPAVPPP---------------------PAPLQIAPGVLHPAPPP 388
                AP  P P                     P     APG L P P P
Sbjct: 640 LAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 689


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 91.7 bits (226), Expect = 2e-18
 Identities = 90/302 (29%), Positives = 115/302 (38%), Gaps = 72/302 (23%)

Query: 274 RPHEPPPPPPMHGAGDA--KPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPL 331
           R   PPP P +    D+   P+P+          NR   P  G       P+P P PPP 
Sbjct: 166 RNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPR---QPSPGPTPPPF 222

Query: 332 P--------------SALSTSSLRASMTSTPPPPV------PPPPPPPA---TALQAPAV 368
           P              S LS+SS  ++    PP P       PPPPPPP     ++   AV
Sbjct: 223 PGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAV 282

Query: 369 PPPP-------APLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVP---------- 411
           PPPP        P    P     APPP  PP     PP+  ++   +  P          
Sbjct: 283 PPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLS 342

Query: 412 --VHPLPQ-GEVQGLPPPP---PPPPL-PPPG----IRPSSPVT---VTALAHPPSGLHP 457
               PLP  G    LPPPP   PPPP+  PPG    + P  PV+    T+ A P +   P
Sbjct: 343 SSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLP 402

Query: 458 TPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQ 517
           + S    P     PP PP +    + P   PST             +IR G Q    E++
Sbjct: 403 SRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPST-------------SIRNGFQDSPCEDE 449

Query: 518 RE 519
            E
Sbjct: 450 WE 451



 Score = 80.1 bits (196), Expect = 5e-15
 Identities = 75/233 (32%), Positives = 91/233 (39%), Gaps = 61/233 (26%)

Query: 253 SALPFSQMSELLTRAEERVLVRPHEPPPP----PPMHGAGDAKPIPTCISSATGLIENRP 308
           S+ PFS    L       +  +P  PPPP    P +H      P P           N+P
Sbjct: 242 SSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQ---------NNKP 292

Query: 309 QSPATGRTPVFVSPTPPPP------PPPLPSALSTSSLRASM--------TSTPPPPVP- 353
             P+T R        PPPP      PPPLP + S +     +        +STPP P P 
Sbjct: 293 PVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPG 352

Query: 354 ---PPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETV 410
              P PPPP+          PP P++  PG   P PPP         PPV+R       +
Sbjct: 353 RSGPLPPPPSER--------PPPPVRDPPGRSGPLPPP---------PPVSRNGSTSRAL 395

Query: 411 PVHP-LPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTA 462
           P  P LP       P   P PPLPP   RPS      A A PP    P PST+
Sbjct: 396 PATPQLPSRSGVDSPRSGPRPPLPPD--RPS------AGAPPP----PPPSTS 436



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 68/240 (28%), Positives = 90/240 (37%), Gaps = 60/240 (25%)

Query: 308 PQSPATGRTPVFVSPTPPPPPP---PLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQ 364
           P  P  GR+     P  PP  P   P+PS            S PP P     PPP   + 
Sbjct: 127 PLLPPGGRS-TSAKPFSPPSGPGRFPVPSP--------GHRSGPPEPQRNRMPPPRPDVG 177

Query: 365 A-PAVPPPPA-----PLQIAP----------GVLHPAPPPIAPPL------------VQP 396
           + P   PPP      P+Q +P          G   P+P P  PP             ++ 
Sbjct: 178 SKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQ 237

Query: 397 SPPVARAAPVCETVPVHPLPQGEVQGLPPPPPP-------------PPLPPPGIRPSSPV 443
           S P++ ++P     P+ P P   +   PPPPPP             PP PP   +P  P 
Sbjct: 238 S-PLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPS 296

Query: 444 TVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRH----PSTLPVISDARS 499
           T    A   +   P P + PGP  P +PPS          P+R+     ST P+ S  RS
Sbjct: 297 TPRPSASSQAPPPPPPPSRPGP--PPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRS 354



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 20/63 (31%), Positives = 27/63 (42%)

Query: 430 PPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPS 489
           PPL PPG R +S    +  + P     P+P    GP  P     PP +    S+P   P 
Sbjct: 126 PPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPP 185

Query: 490 TLP 492
            +P
Sbjct: 186 PVP 188



 Score = 29.6 bits (65), Expect = 7.6
 Identities = 11/15 (73%), Positives = 11/15 (73%)

Query: 348 PPPPVPPPPPPPATA 362
           PPPP PPPPP  A A
Sbjct: 4   PPPPAPPPPPTFALA 18



 Score = 29.3 bits (64), Expect = 10.0
 Identities = 11/16 (68%), Positives = 11/16 (68%)

Query: 348 PPPPVPPPPPPPATAL 363
           P PP P PPPPP  AL
Sbjct: 2   PVPPPPAPPPPPTFAL 17


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 91.7 bits (226), Expect = 2e-18
 Identities = 90/302 (29%), Positives = 115/302 (38%), Gaps = 72/302 (23%)

Query: 274 RPHEPPPPPPMHGAGDA--KPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPL 331
           R   PPP P +    D+   P+P+          NR   P  G       P+P P PPP 
Sbjct: 166 RNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPR---QPSPGPTPPPF 222

Query: 332 P--------------SALSTSSLRASMTSTPPPPV------PPPPPPPA---TALQAPAV 368
           P              S LS+SS  ++    PP P       PPPPPPP     ++   AV
Sbjct: 223 PGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAV 282

Query: 369 PPPP-------APLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVP---------- 411
           PPPP        P    P     APPP  PP     PP+  ++   +  P          
Sbjct: 283 PPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLS 342

Query: 412 --VHPLPQ-GEVQGLPPPP---PPPPL-PPPG----IRPSSPVT---VTALAHPPSGLHP 457
               PLP  G    LPPPP   PPPP+  PPG    + P  PV+    T+ A P +   P
Sbjct: 343 SSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLP 402

Query: 458 TPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQ 517
           + S    P     PP PP +    + P   PST             +IR G Q    E++
Sbjct: 403 SRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPST-------------SIRNGFQDSPCEDE 449

Query: 518 RE 519
            E
Sbjct: 450 WE 451



 Score = 80.1 bits (196), Expect = 5e-15
 Identities = 75/233 (32%), Positives = 91/233 (39%), Gaps = 61/233 (26%)

Query: 253 SALPFSQMSELLTRAEERVLVRPHEPPPP----PPMHGAGDAKPIPTCISSATGLIENRP 308
           S+ PFS    L       +  +P  PPPP    P +H      P P           N+P
Sbjct: 242 SSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQ---------NNKP 292

Query: 309 QSPATGRTPVFVSPTPPPP------PPPLPSALSTSSLRASM--------TSTPPPPVP- 353
             P+T R        PPPP      PPPLP + S +     +        +STPP P P 
Sbjct: 293 PVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPG 352

Query: 354 ---PPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETV 410
              P PPPP+          PP P++  PG   P PPP         PPV+R       +
Sbjct: 353 RSGPLPPPPSER--------PPPPVRDPPGRSGPLPPP---------PPVSRNGSTSRAL 395

Query: 411 PVHP-LPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTA 462
           P  P LP       P   P PPLPP   RPS      A A PP    P PST+
Sbjct: 396 PATPQLPSRSGVDSPRSGPRPPLPPD--RPS------AGAPPP----PPPSTS 436



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 68/240 (28%), Positives = 90/240 (37%), Gaps = 60/240 (25%)

Query: 308 PQSPATGRTPVFVSPTPPPPPP---PLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQ 364
           P  P  GR+     P  PP  P   P+PS            S PP P     PPP   + 
Sbjct: 127 PLLPPGGRS-TSAKPFSPPSGPGRFPVPSP--------GHRSGPPEPQRNRMPPPRPDVG 177

Query: 365 A-PAVPPPPA-----PLQIAP----------GVLHPAPPPIAPPL------------VQP 396
           + P   PPP      P+Q +P          G   P+P P  PP             ++ 
Sbjct: 178 SKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQ 237

Query: 397 SPPVARAAPVCETVPVHPLPQGEVQGLPPPPPP-------------PPLPPPGIRPSSPV 443
           S P++ ++P     P+ P P   +   PPPPPP             PP PP   +P  P 
Sbjct: 238 S-PLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPS 296

Query: 444 TVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRH----PSTLPVISDARS 499
           T    A   +   P P + PGP  P +PPS          P+R+     ST P+ S  RS
Sbjct: 297 TPRPSASSQAPPPPPPPSRPGP--PPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRS 354



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 20/63 (31%), Positives = 27/63 (42%)

Query: 430 PPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPS 489
           PPL PPG R +S    +  + P     P+P    GP  P     PP +    S+P   P 
Sbjct: 126 PPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPP 185

Query: 490 TLP 492
            +P
Sbjct: 186 PVP 188



 Score = 29.6 bits (65), Expect = 7.6
 Identities = 11/15 (73%), Positives = 11/15 (73%)

Query: 348 PPPPVPPPPPPPATA 362
           PPPP PPPPP  A A
Sbjct: 4   PPPPAPPPPPTFALA 18



 Score = 29.3 bits (64), Expect = 10.0
 Identities = 11/16 (68%), Positives = 11/16 (68%)

Query: 348 PPPPVPPPPPPPATAL 363
           P PP P PPPPP  AL
Sbjct: 2   PVPPPPAPPPPPTFAL 17


>gi|150417989 cyclin K isoform 1 [Homo sapiens]
          Length = 580

 Score = 90.1 bits (222), Expect = 5e-18
 Identities = 110/421 (26%), Positives = 157/421 (37%), Gaps = 98/421 (23%)

Query: 68  SLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIPLQETYDV 127
           SLQ   + ++V+V  L  +  +  +Q+ T +  +R       + +++    +P+    D+
Sbjct: 198 SLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYR-------RWWEQFVQDVPVDVLEDI 250

Query: 128 CEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDT------------------ 169
           C Q     IL  Y   GK+ +  +T       L +   LQ T                  
Sbjct: 251 CHQ-----ILDLY-SQGKQQMPHHTP----HQLQQPPSLQPTPQVPQVQQSQPSQSSEPS 300

Query: 170 --EDKRKEKRKQKQKNLDRPHEPEKVPRAPHDRRR-------EWQKLAQGPELAEDDANL 220
             + K  ++  Q+Q+   +P +P   P +P   +R       E  K A+ P         
Sbjct: 301 QPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIET 360

Query: 221 LHKHIEVANGP--------ASHFETRPQTYVDHMDGSYSLSALPFSQMSELLTRAE-ERV 271
            H  +  A+ P        A+  E  P   VD  D       LP  Q+      A   + 
Sbjct: 361 THPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATD-------LPKVQIPPPAHPAPVHQP 413

Query: 272 LVRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPL 331
              PH PPPPPP   +     + T  S  +G      QS      P + +  P   PP  
Sbjct: 414 PPLPHRPPPPPP---SSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPP-- 468

Query: 332 PSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAP 391
                 + L       PP P PPP PPP  +   PA+PPP       PG  +P PPP   
Sbjct: 469 ------AHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPP------TPG--YPPPPPTYN 514

Query: 392 PLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPP-------------PPPPPPLPPPGIR 438
           P   P PP     P    VP HP P     GLPP             PP PPP+PPPG+ 
Sbjct: 515 PNFPPPPP---RLPPTHAVPPHPPPG---LGLPPASYPPPAVPPGGQPPVPPPIPPPGMP 568

Query: 439 P 439
           P
Sbjct: 569 P 569



 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 67/219 (30%), Positives = 81/219 (36%), Gaps = 50/219 (22%)

Query: 307 RPQSPATGRTPVFVSP-----TPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPP--PP 359
           +P SP   +  V VSP        PPPP +P        +   T  P PP  PPP   PP
Sbjct: 326 QPSSPRQVKRAVVVSPKEENKAAEPPPPKIP--------KIETTHPPLPPAHPPPDRKPP 377

Query: 360 ATALQAPAVPPPPAPLQIAPGV-----LHPAPPPIAPPLVQ--PSPPVARAAPVCETVPV 412
             A    A PP P      P V      HPAP    PPL    P PP +       T   
Sbjct: 378 LAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSS 437

Query: 413 HPLPQG--------EVQG-----LPP---PP----------PPPPLPPPGIRPSSPVTVT 446
           +   +G        + +G     LPP   PP          PP P PPP   P +     
Sbjct: 438 YMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPP 497

Query: 447 ALAHPPSGLHPTPSTAPGPHVPLMPPS-PPSQVIPASEP 484
           A+  P  G  P P T   P+ P  PP  PP+  +P   P
Sbjct: 498 AIPPPTPGYPPPPPTY-NPNFPPPPPRLPPTHAVPPHPP 535



 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 66/252 (26%), Positives = 83/252 (32%), Gaps = 51/252 (20%)

Query: 275 PHEPPPPPPMHGAGDAKPI----PTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPP 330
           PH+   PP +        +    P+  S  +   +  PQ PA  + P       P  P P
Sbjct: 270 PHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPA----QQPKKPSP 325

Query: 331 LPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAP---P 387
            PS+         ++         PPPP    ++    P PPA         HP P   P
Sbjct: 326 QPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPA---------HPPPDRKP 376

Query: 388 PIAPPLVQPSPPVARAAPVCETV----PVHPLPQGEVQGLP--PPPPPPPLPPPGIRPSS 441
           P+A  L +  PP    A     V    P HP P  +   LP  PPPPPP     G+  +S
Sbjct: 377 PLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTS 436

Query: 442 -------------------------PVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPS 476
                                    P      AH P   H  P   P P VP  P S P 
Sbjct: 437 SYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPP 496

Query: 477 QVIPASEPKRHP 488
             IP   P   P
Sbjct: 497 PAIPPPTPGYPP 508



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 16/43 (37%), Positives = 20/43 (46%)

Query: 450 HPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLP 492
           H P  L   PS  P P VP +  S PSQ    S+P++     P
Sbjct: 268 HTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQP 310


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 84/247 (34%), Positives = 100/247 (40%), Gaps = 33/247 (13%)

Query: 311 PATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPP 370
           P   R P    P  PPPP P         L       P PP PP PPPP   L  P   P
Sbjct: 212 PGGDRFPGPAGPGGPPPPFPAGQTPPRPPL-----GPPGPPGPPGPPPPGQVLPPPLAGP 266

Query: 371 PPAPLQIAPGVLHP----APPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPP 426
           P    +  P VL P      PP+ P    P PPV    P     P  P PQ   QG PPP
Sbjct: 267 PNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGP----PPGPPPPQ---QGPPPP 319

Query: 427 PPP-PPLPPPGIRPSSPVTVTALAH---PPSGLHPTPSTAPGPHV-PLMPPSPPSQVIPA 481
           P P PP PP  + P  P+T+    H   PP G  P     P PHV P   P P +  +P 
Sbjct: 320 PGPFPPRPPGPLGP--PLTLAPPPHLPGPPPGAPP-----PAPHVNPAFFPPPTNSGMPT 372

Query: 482 SEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQRE--QEAKHERIENDVATILSRRI 539
           S+ +  P T P     R    +    G   R+++  R    EA+ E I N    I S  I
Sbjct: 373 SDSRGPPPTDPY---GRPPPYDRGDYGPPGREMDTARTPLSEAEFEEIMNRNRAISSSAI 429

Query: 540 AVEYSDS 546
           +   SD+
Sbjct: 430 SRAVSDA 436



 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 71/202 (35%), Positives = 75/202 (37%), Gaps = 34/202 (16%)

Query: 275 PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSA 334
           P  P  PPP   AG   P P             P  P     P    P PPPP   LP  
Sbjct: 220 PAGPGGPPPPFPAGQTPPRP-------------PLGPPGPPGP----PGPPPPGQVLPPP 262

Query: 335 LSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLV 394
           L+    R      PPPPV  P  P     Q P  P PP P    PG     PPP  PP  
Sbjct: 263 LAGPPNRG---DRPPPPVLFPGQPFG---QPPLGPLPPGPPPPVPGY---GPPPGPPPPQ 313

Query: 395 QPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPP-- 452
           Q  PP     P     P  P P G    L PPP  P  PPPG  P +P    A   PP  
Sbjct: 314 QGPPPPPGPFP-----PRPPGPLGPPLTLAPPPHLPG-PPPGAPPPAPHVNPAFFPPPTN 367

Query: 453 SGLHPTPSTAPGPHVPLMPPSP 474
           SG+  + S  P P  P   P P
Sbjct: 368 SGMPTSDSRGPPPTDPYGRPPP 389


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 87.4 bits (215), Expect = 3e-17
 Identities = 110/426 (25%), Positives = 143/426 (33%), Gaps = 117/426 (27%)

Query: 162 KEKMLQDTEDK-RKEKRKQKQKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANL 220
           +EK+  DTE+  R   +K K + + RP+ P +      D R              D+ + 
Sbjct: 97  REKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRS-----------VNDEGSS 145

Query: 221 LHKHIEVANGPASHFETRPQTYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPP 280
             K I+  N   S     PQ      D S     L   Q      +A   V   P   PP
Sbjct: 146 DPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQML---QAQPPALQAPTGVTPAPSSAPP 202

Query: 281 PPPMHGAGDAKPIPTCI----SSATGLIENRPQSPATGRTPVFV------------SPTP 324
             P        P  T +    S       N+PQ+P        +            SP P
Sbjct: 203 GTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHP 262

Query: 325 PPPPPPLP--SALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAV-----PPPP----- 372
           PP P P P    L+ S+ + S  S   PP+    PP   +LQA  +     PP P     
Sbjct: 263 PPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPP 322

Query: 373 ------APLQIAPGVLHP-----------APPPIAPPLVQPSPPVARAAPVCETVPVHPL 415
                 APL  +P   +P           A     PP  QP PP   A P  +  P  P+
Sbjct: 323 QASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPI 382

Query: 416 PQGEVQ-------------------GLPPPP-----------------PPP--------P 431
           PQ                        LPPPP                 PPP        P
Sbjct: 383 PQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQP 442

Query: 432 LP-----PPGIRPSSPVTVTALAHPPSGLH---PTPSTA-----PGPHVPLMPPSPPSQV 478
           LP     PPG+  S  +     +HPP+GLH   P P  A     PG   P+ PP+ PS  
Sbjct: 443 LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTS 502

Query: 479 IPASEP 484
            P + P
Sbjct: 503 TPPAGP 508



 Score = 69.3 bits (168), Expect = 9e-12
 Identities = 83/307 (27%), Positives = 106/307 (34%), Gaps = 71/307 (23%)

Query: 230 GPASHFETRPQTYVDHMD-GSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAG 288
           GP   F   PQ        G+   +A P + +    +++  +    P E P PP      
Sbjct: 313 GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMP 372

Query: 289 DAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPP-----PPPPLPSALSTSSLRAS 343
             KP PT        I   P   A    P    P+P       PPPP    LS+ S    
Sbjct: 373 HIKPPPTTP------IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHP 426

Query: 344 MTSTPPP--------PVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            ++ PPP        P+P  P  P    Q+  +PPPPA           + PP     V 
Sbjct: 427 PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPA-----------SHPPTGLHQVA 475

Query: 396 PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPP--- 452
           P PP A+          HP     V G PPP  PP  P     P+ P T    A PP   
Sbjct: 476 PQPPFAQ----------HPF----VPGGPPPITPPTCPSTSTPPAGPGT---SAQPPCSG 518

Query: 453 ----SGLHPTPSTAPGPHVPLM---------PPSPPSQVIPASEPKRHPSTLPVISDARS 499
                G     S+ P P V +          P SPP        P R PS  P + D  S
Sbjct: 519 AAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP-------PPPRSPSPEPTVVDTPS 571

Query: 500 VLLEAIR 506
              ++ R
Sbjct: 572 HASQSAR 578


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 87.4 bits (215), Expect = 3e-17
 Identities = 110/426 (25%), Positives = 143/426 (33%), Gaps = 117/426 (27%)

Query: 162  KEKMLQDTEDK-RKEKRKQKQKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANL 220
            +EK+  DTE+  R   +K K + + RP+ P +      D R              D+ + 
Sbjct: 651  REKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRS-----------VNDEGSS 699

Query: 221  LHKHIEVANGPASHFETRPQTYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPP 280
              K I+  N   S     PQ      D S     L   Q      +A   V   P   PP
Sbjct: 700  DPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQML---QAQPPALQAPTGVTPAPSSAPP 756

Query: 281  PPPMHGAGDAKPIPTCI----SSATGLIENRPQSPATGRTPVFV------------SPTP 324
              P        P  T +    S       N+PQ+P        +            SP P
Sbjct: 757  GTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHP 816

Query: 325  PPPPPPLP--SALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAV-----PPPP----- 372
            PP P P P    L+ S+ + S  S   PP+    PP   +LQA  +     PP P     
Sbjct: 817  PPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPP 876

Query: 373  ------APLQIAPGVLHP-----------APPPIAPPLVQPSPPVARAAPVCETVPVHPL 415
                  APL  +P   +P           A     PP  QP PP   A P  +  P  P+
Sbjct: 877  QASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPI 936

Query: 416  PQGEVQ-------------------GLPPPP-----------------PPP--------P 431
            PQ                        LPPPP                 PPP        P
Sbjct: 937  PQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQP 996

Query: 432  LP-----PPGIRPSSPVTVTALAHPPSGLH---PTPSTA-----PGPHVPLMPPSPPSQV 478
            LP     PPG+  S  +     +HPP+GLH   P P  A     PG   P+ PP+ PS  
Sbjct: 997  LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTS 1056

Query: 479  IPASEP 484
             P + P
Sbjct: 1057 TPPAGP 1062



 Score = 69.3 bits (168), Expect = 9e-12
 Identities = 83/307 (27%), Positives = 106/307 (34%), Gaps = 71/307 (23%)

Query: 230  GPASHFETRPQTYVDHMD-GSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAG 288
            GP   F   PQ        G+   +A P + +    +++  +    P E P PP      
Sbjct: 867  GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMP 926

Query: 289  DAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPP-----PPPPLPSALSTSSLRAS 343
              KP PT        I   P   A    P    P+P       PPPP    LS+ S    
Sbjct: 927  HIKPPPTTP------IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHP 980

Query: 344  MTSTPPP--------PVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
             ++ PPP        P+P  P  P    Q+  +PPPPA           + PP     V 
Sbjct: 981  PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPA-----------SHPPTGLHQVA 1029

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPP--- 452
            P PP A+          HP     V G PPP  PP  P     P+ P T    A PP   
Sbjct: 1030 PQPPFAQ----------HPF----VPGGPPPITPPTCPSTSTPPAGPGT---SAQPPCSG 1072

Query: 453  ----SGLHPTPSTAPGPHVPLM---------PPSPPSQVIPASEPKRHPSTLPVISDARS 499
                 G     S+ P P V +          P SPP        P R PS  P + D  S
Sbjct: 1073 AAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP-------PPPRSPSPEPTVVDTPS 1125

Query: 500  VLLEAIR 506
               ++ R
Sbjct: 1126 HASQSAR 1132


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 87.4 bits (215), Expect = 3e-17
 Identities = 110/426 (25%), Positives = 143/426 (33%), Gaps = 117/426 (27%)

Query: 162  KEKMLQDTEDK-RKEKRKQKQKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANL 220
            +EK+  DTE+  R   +K K + + RP+ P +      D R              D+ + 
Sbjct: 651  REKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRS-----------VNDEGSS 699

Query: 221  LHKHIEVANGPASHFETRPQTYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPP 280
              K I+  N   S     PQ      D S     L   Q      +A   V   P   PP
Sbjct: 700  DPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQML---QAQPPALQAPTGVTPAPSSAPP 756

Query: 281  PPPMHGAGDAKPIPTCI----SSATGLIENRPQSPATGRTPVFV------------SPTP 324
              P        P  T +    S       N+PQ+P        +            SP P
Sbjct: 757  GTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHP 816

Query: 325  PPPPPPLP--SALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAV-----PPPP----- 372
            PP P P P    L+ S+ + S  S   PP+    PP   +LQA  +     PP P     
Sbjct: 817  PPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPP 876

Query: 373  ------APLQIAPGVLHP-----------APPPIAPPLVQPSPPVARAAPVCETVPVHPL 415
                  APL  +P   +P           A     PP  QP PP   A P  +  P  P+
Sbjct: 877  QASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPI 936

Query: 416  PQGEVQ-------------------GLPPPP-----------------PPP--------P 431
            PQ                        LPPPP                 PPP        P
Sbjct: 937  PQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQP 996

Query: 432  LP-----PPGIRPSSPVTVTALAHPPSGLH---PTPSTA-----PGPHVPLMPPSPPSQV 478
            LP     PPG+  S  +     +HPP+GLH   P P  A     PG   P+ PP+ PS  
Sbjct: 997  LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTS 1056

Query: 479  IPASEP 484
             P + P
Sbjct: 1057 TPPAGP 1062



 Score = 69.3 bits (168), Expect = 9e-12
 Identities = 83/307 (27%), Positives = 106/307 (34%), Gaps = 71/307 (23%)

Query: 230  GPASHFETRPQTYVDHMD-GSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAG 288
            GP   F   PQ        G+   +A P + +    +++  +    P E P PP      
Sbjct: 867  GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMP 926

Query: 289  DAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPP-----PPPPLPSALSTSSLRAS 343
              KP PT        I   P   A    P    P+P       PPPP    LS+ S    
Sbjct: 927  HIKPPPTTP------IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHP 980

Query: 344  MTSTPPP--------PVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
             ++ PPP        P+P  P  P    Q+  +PPPPA           + PP     V 
Sbjct: 981  PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPA-----------SHPPTGLHQVA 1029

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPP--- 452
            P PP A+          HP     V G PPP  PP  P     P+ P T    A PP   
Sbjct: 1030 PQPPFAQ----------HPF----VPGGPPPITPPTCPSTSTPPAGPGT---SAQPPCSG 1072

Query: 453  ----SGLHPTPSTAPGPHVPLM---------PPSPPSQVIPASEPKRHPSTLPVISDARS 499
                 G     S+ P P V +          P SPP        P R PS  P + D  S
Sbjct: 1073 AAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP-------PPPRSPSPEPTVVDTPS 1125

Query: 500  VLLEAIR 506
               ++ R
Sbjct: 1126 HASQSAR 1132


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
           sapiens]
          Length = 2715

 Score = 86.7 bits (213), Expect = 5e-17
 Identities = 87/277 (31%), Positives = 115/277 (41%), Gaps = 45/277 (16%)

Query: 277 EPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP---- 332
           +PP PP +  +   +P P   S         PQ PA   +P   +PTPP  P PLP    
Sbjct: 550 DPPKPPKVEVSPVLRP-PITTSPPV------PQEPAPVPSPPR-APTPPSTPVPLPEKRR 601

Query: 333 SALSTSSLR-ASMTST--PPPPVPPPPP----PPATA--------LQAPAVPPPPAPLQI 377
           S L   + R  S+T    PPPP PPPPP    PPA A        L+AP   P  A L+I
Sbjct: 602 SILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKI 661

Query: 378 APGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGI 437
              VL P PP  AP   +P PP A  +P        P   G    L  P   P +  P  
Sbjct: 662 YESVLTP-PPLGAPEAPEPEPPPADDSPA----EPEPRAVGRTNHLSLPRFAPVVTTPVK 716

Query: 438 RPSSPVTVTALAHPPSG----LHPT--------PSTAPGPHVPLMPPSPPSQVIPASEPK 485
              SP    AL++ P      L P         P   P P   L PP  P Q+ P  + +
Sbjct: 717 AEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKAR 776

Query: 486 -RHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQE 521
                +LP+      +     R  +QL K+++Q++Q+
Sbjct: 777 IAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQK 813



 Score = 72.8 bits (177), Expect = 8e-13
 Identities = 81/305 (26%), Positives = 100/305 (32%), Gaps = 112/305 (36%)

Query: 275 PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPP-------- 326
           P  P PPPP+     + P P C           P  P     P   SP PPP        
Sbjct: 408 PPAPSPPPPLPPPSTSPPPPLC-----------PPPPPPVSPPPLPSPPPPPAQEEQEES 456

Query: 327 PPPPLPSALSTSSLRASMTSTP----------PPPVPPPPPPPATALQAPAV-------- 368
           PPP +P+  S    R  +T +           P    PP P P+TA   P          
Sbjct: 457 PPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPK 516

Query: 369 ----------------------------------PPPPAPLQIAPGVLHP----APPPIA 390
                                             PP P  ++++P VL P    +PP   
Sbjct: 517 STTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSP-VLRPPITTSPPVPQ 575

Query: 391 PPLVQPSPPVARAAPVCETVPVHPLPQGE--------------VQGLPPPPPPPPLPPPG 436
            P   PSPP    AP   + PV PLP+                 + LPPPPP PP PP  
Sbjct: 576 EPAPVPSPP---RAPTPPSTPV-PLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAP 631

Query: 437 IRPSSPVT-------VTALAHPPSGLH---------PTPSTAPGPHVPLMPPSPPSQVIP 480
             P +P T       + A    PS  H         P P  AP    P  PP+  S   P
Sbjct: 632 SPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEP 691

Query: 481 ASEPK 485
             EP+
Sbjct: 692 --EPR 694



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 64/218 (29%), Positives = 82/218 (37%), Gaps = 67/218 (30%)

Query: 317 PVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQ 376
           P  ++P  P PPPPLP            +++PPPP+ PPPPPP +    P+ PPPPA  +
Sbjct: 403 PPPLTPPAPSPPPPLPPP----------STSPPPPLCPPPPPPVSPPPLPSPPPPPAQEE 452

Query: 377 IAPGVLHPAPPPIAP---------PLVQPSP----PVARAAPVCETVPVHPLPQGEVQGL 423
                   +PPP+ P         P + PS       ARA P   T P  P P     G 
Sbjct: 453 -----QEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPE-GTSPPTPTPSTATGG- 505

Query: 424 PPPPPPPPLPPPGIR-------------------------------PSSP--VTVTALAH 450
            PP   P + P                                   P  P  V V+ +  
Sbjct: 506 -PPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLR 564

Query: 451 PPSGLHPTPSTAPGPHVPLMP--PSPPSQVIPASEPKR 486
           PP    P     P P VP  P  P+PPS  +P  E +R
Sbjct: 565 PPITTSPPVPQEPAP-VPSPPRAPTPPSTPVPLPEKRR 601



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 49/145 (33%), Positives = 56/145 (38%), Gaps = 39/145 (26%)

Query: 327 PPPPLPSALSTSSLRASMTSTPPPPVPPPP-PPPATALQAPAVPPPPAPLQIAPGVLHPA 385
           PPPPL               TPP P PPPP PPP+T+   P  PPPP             
Sbjct: 402 PPPPL---------------TPPAPSPPPPLPPPSTSPPPPLCPPPP------------- 433

Query: 386 PPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLP-------PPGIR 438
           PP   PPL  P PP A+        PV P      +G PP  P            P G  
Sbjct: 434 PPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTS 493

Query: 439 PSSPVTVTALAHPPSGLHPTPSTAP 463
           P +P   TA   PP     +P+ AP
Sbjct: 494 PPTPTPSTATGGPP---EDSPTVAP 515



 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 54/170 (31%), Positives = 73/170 (42%), Gaps = 21/170 (12%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            PP PP  +G+  ++ +    +  T      P +P  G   + + P P PP P     +  
Sbjct: 2137 PPAPPLANGSQPSQGLTASPADPTRTFAWLPGAP--GVRVLSLGPAPEPPKPATSKIILV 2194

Query: 338  SSL------RASMTSTPPPPVPPPPPPPATALQAP---AVPPPPAPLQIAP--GVLHPAP 386
            + L       A      PPPV  PP PP  +  AP    +PP P  L + P  GV+ PAP
Sbjct: 2195 NKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPL-LGVLPVVGVVRPAP 2253

Query: 387  PPIAPP--LVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPP 434
            PP  PP  LV  S P   A+P  + + V  +      G  PP PPP   P
Sbjct: 2254 PPPPPPLTLVLSSGP---ASPPRQAIRVKRV--STFSGRSPPAPPPYKAP 2298



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 51/171 (29%), Positives = 62/171 (36%), Gaps = 24/171 (14%)

Query: 277  EPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVF--VSPTPPPPPPPLPSA 334
            EP PPP         P+P  IS         P  P  G  PV   V P PPPPPPPL   
Sbjct: 2209 EPVPPPVKQ-----PPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLV 2263

Query: 335  LSTSSL----------RASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGV--- 381
            LS+             R S  S   PP PPP   P       A    P    +  G    
Sbjct: 2264 LSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSR 2323

Query: 382  LHPAPPPIAP--PLVQPSPPVARAAP--VCETVPVHPLPQGEVQGLPPPPP 428
            +    P +     L +P  P    +P  + E  P+ PLP+     +P  PP
Sbjct: 2324 VRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPP 2374



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 53/173 (30%), Positives = 66/173 (38%), Gaps = 42/173 (24%)

Query: 358 PPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQ 417
           P A   +A   PPP  P   +P      PPP+ PP   P PP+    P   + P  PLP 
Sbjct: 392 PAAEKEEAKLPPPPLTPPAPSP------PPPLPPPSTSPPPPLCPPPPPPVSPP--PLPS 443

Query: 418 GEVQGLPPPPP--------PPPLPP---------PGIRPSSPVTVTALAHPPSGLH---P 457
                 PPPPP        PPP+ P         P + PS      A    P G     P
Sbjct: 444 ------PPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTP 497

Query: 458 TPSTAPGPHVPLMPPSPPSQVIPASE---PKRHPSTLPVISDARSVLLEAIRK 507
           TPSTA G      PP     V P S           +PV+S   S +++  R+
Sbjct: 498 TPSTATGG-----PPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRR 545



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 51/190 (26%), Positives = 67/190 (35%), Gaps = 37/190 (19%)

Query: 272 LVRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQ-SPATGRTPVFVSPTPPPPPPP 330
           L R   PPPP P      + P     SS   L+   PQ +P+     ++ S   PPP   
Sbjct: 614 LTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPP--- 670

Query: 331 LPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAP--------LQIAPGVL 382
                              P  P P PPPA    +PA P P A          + AP V 
Sbjct: 671 ----------------LGAPEAPEPEPPPAD--DSPAEPEPRAVGRTNHLSLPRFAPVVT 712

Query: 383 HPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLP---PPPPPPPLPPPGIRP 439
            P    ++P       P     P  +   + PL   + Q LP   PPP P   PPP  + 
Sbjct: 713 TPVKAEVSP----HGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQ 768

Query: 440 SSPVTVTALA 449
             P+    +A
Sbjct: 769 MPPLEKARIA 778



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 55/201 (27%), Positives = 77/201 (38%), Gaps = 30/201 (14%)

Query: 256  PFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQ--SPAT 313
            P  + + L    E + +V    P   PP    G+  P+ T +     L+   P+  SP  
Sbjct: 1788 PREEPAHLEAAEENQTIVHSPAPSSEPP---GGEDPPLDTDV-----LVPGAPERHSPIQ 1839

Query: 314  GRTPVFVSPTPPPPPPPLPSALSTSSL--------RASMTSTPPPPVPPPPPPPATALQA 365
               P  + P     PPP P + S + +        R  +      P+P P  P +     
Sbjct: 1840 NLDPP-LRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHI 1898

Query: 366  PAVPPP--PAPLQIA--PGVLHPAPPP---IAPPLVQPSPPVARAAPVCETVPVHPLPQG 418
            P V  P  PAP + +  P  L P PPP    +PPL   + P  R  P    V       G
Sbjct: 1899 PTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPL--KTSPQLRVPPPTSVVTALTPTSG 1956

Query: 419  EVQGLPPPPPPPPLPPPGIRP 439
            E+   PP P P P PP  + P
Sbjct: 1957 ELA--PPGPAPSPPPPEDLGP 1975



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 58/197 (29%), Positives = 74/197 (37%), Gaps = 41/197 (20%)

Query: 327  PPPPLPSALSTSSLR-----ASMTSTPPPPVPPPPPPPATALQAP----AVPPPP----A 373
            PP  LPS +    L+         + P     PP PP A   Q      A P  P    A
Sbjct: 2105 PPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFA 2164

Query: 374  PLQIAPGV----LHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPP 429
             L  APGV    L PAP P       P P  ++   V +   V     GE +        
Sbjct: 2165 WLPGAPGVRVLSLGPAPEP-------PKPATSKIILVNKLGQVFVKMAGEGE-------- 2209

Query: 430  PPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPS 489
             P+PPP  +P  P T++  A     L P P     P V ++ P+PP        P   P 
Sbjct: 2210 -PVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPP--------PPPPPL 2260

Query: 490  TLPVISDARSVLLEAIR 506
            TL + S   S   +AIR
Sbjct: 2261 TLVLSSGPASPPRQAIR 2277



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 42/164 (25%), Positives = 59/164 (35%), Gaps = 19/164 (11%)

Query: 325  PPPPPPLPSALSTSSLRASMTSTPPPPVPPP---PPPPATALQAPAVPPPPAPLQIAPGV 381
            P  P   P+ L  +    ++  +P P   PP    PP  T +  P  P   +P+Q     
Sbjct: 1785 PWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQ----- 1839

Query: 382  LHPAPPPIAPPLVQPSPPVARAAPVCET-VPVHPLPQGEVQGLPPPPPPPPLPPPGIRPS 440
                 PP+ P      PP  R+       VP +   +  + G+   P    LP PG   S
Sbjct: 1840 --NLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGP----LPSPGSPSS 1893

Query: 441  SPVTVTALAHPPSGLHPTPSTAPGPHVPLMPP----SPPSQVIP 480
                +  +  P     P  S  P P  P  PP    SPP +  P
Sbjct: 1894 LTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSP 1937



 Score = 33.5 bits (75), Expect = 0.53
 Identities = 26/96 (27%), Positives = 32/96 (33%), Gaps = 11/96 (11%)

Query: 260 MSELLTRAEERVLVRPH--EPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTP 317
           ++ELL RA+     R    EP  P    G    +P   C          R Q        
Sbjct: 193 LTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPC---------RRKQQAVVVAEA 243

Query: 318 VFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVP 353
               P P PPPP +P    T S +      P P  P
Sbjct: 244 AVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTP 279



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 28/99 (28%), Positives = 33/99 (33%), Gaps = 19/99 (19%)

Query: 355 PPPPPATALQAPAVPPPPAP----------LQIAPGVLHPAPPPIAP---------PLVQ 395
           P PPP  A  AP  P  PA           +Q    +L  A  P AP         P   
Sbjct: 160 PLPPPRLADVAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRS 219

Query: 396 PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPP 434
              P  R A  C       +       +P P PPPP+ P
Sbjct: 220 RGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVP 258


>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
          Length = 464

 Score = 86.7 bits (213), Expect = 5e-17
 Identities = 70/205 (34%), Positives = 85/205 (41%), Gaps = 43/205 (20%)

Query: 304 IENRPQSPATGRTPVFVSPTPPP------PPPPLPSALSTSSLRASMTSTPPPP--VPPP 355
           +E  P  P+    P  V   PPP      P PPLP +L            PPPP  +P P
Sbjct: 214 MEKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLP-----------PPPPGGLPLP 262

Query: 356 PPPPATALQAPAVPPPPAPLQI---APGVLHPAPPPIAPPLVQPSPPVARAAPVCETV-- 410
           P PP      PA   PP P Q+   APGV HP  P + PP     PP     P    V  
Sbjct: 263 PMPPT----GPAPSGPPGPPQLPPPAPGV-HPPAPVVHPPASGVHPPAPGVHPPAPGVHP 317

Query: 411 ---PVHPLPQG---EVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPS-GLHPTPSTAP 463
               VHP   G      G+ PP P    P PG+ P +P       HPP+ G+HP PS   
Sbjct: 318 PAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPG-----VHPPAPGVHPPPSAGV 372

Query: 464 GPHVPLMPPSPPSQVIPASEPKRHP 488
            P  P + P+ P+  +    P  HP
Sbjct: 373 HPQAPGVHPAAPA--VHPQAPGVHP 395



 Score = 86.7 bits (213), Expect = 5e-17
 Identities = 73/233 (31%), Positives = 92/233 (39%), Gaps = 26/233 (11%)

Query: 279 PPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTS 338
           PPPP M+G     P+P  +          P  P TG  P    P PP  PPP P     +
Sbjct: 233 PPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSG-PPGPPQLPPPAPGVHPPA 291

Query: 339 SL---RASMTSTPPPPVPPPPP---PPATALQAPAV---PPPPAPLQIAPGV------LH 383
            +    AS    P P V PP P   PPA  +  P     PP P     APGV      +H
Sbjct: 292 PVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVH 351

Query: 384 PAPPPIAPPL--VQPSPPVARAAPVCETV-PVHPLPQGEVQGLPPPPPPPPLPPPGIRPS 440
           P  P + PP   V P PP A   P    V P  P    +  G+ PP P      PG+ P 
Sbjct: 352 PPAPGVHPPAPGVHP-PPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQ 410

Query: 441 SPVTVTALAHPPS-GLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLP 492
            P       HP + G+HP P      +  + PP+P   ++    P   P  +P
Sbjct: 411 PPGV-----HPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNIP 458



 Score = 66.6 bits (161), Expect = 6e-11
 Identities = 60/177 (33%), Positives = 68/177 (38%), Gaps = 58/177 (32%)

Query: 325 PPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHP 384
           PP PP LP+               PP V  PPPP    L     P PP P  + P     
Sbjct: 217 PPAPPSLPAG--------------PPGVKRPPPPLMNGLP----PRPPLPESLPP----- 253

Query: 385 APPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVT 444
            PPP   PL    PP+          P  P P G     PP PP  P P PG+ P +PV 
Sbjct: 254 -PPPGGLPL----PPMP---------PTGPAPSG-----PPGPPQLPPPAPGVHPPAPVV 294

Query: 445 VTALAHPP-SGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDARSV 500
                HPP SG+HP    APG         PP+  +    P  HP T  V   A  V
Sbjct: 295 -----HPPASGVHPP---APG-------VHPPAPGVHPPAPGVHPPTSGVHPPAPGV 336


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 86.3 bits (212), Expect = 7e-17
 Identities = 81/260 (31%), Positives = 99/260 (38%), Gaps = 50/260 (19%)

Query: 252 LSALPFSQMSELLTRAEERVLVRPHEPPP--PPPMHGAGDAKPIPTCISSATGLIENRPQ 309
           L A P  +   L    EE  L  P E  P  PPP     ++ P      S     E  P 
Sbjct: 474 LPASPLPEALHLSRPLEESPLSPPPEESPLSPPP-----ESSPFSPLEESPLSPPEESPP 528

Query: 310 SPATGRTPVFVSPTPPPPPPPL------------PSALSTSSLRASMTSTPPPPVPPPPP 357
           SPA   TP+    +PPP   PL            P  L TS    +   +PPP   P  P
Sbjct: 529 SPAL-ETPL----SPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSP 583

Query: 358 PPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQ 417
           PP    ++P  PPP A     P    P  PP     + P P  +R +P  E  P+     
Sbjct: 584 PPE---ESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMS---- 636

Query: 418 GEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPP---SGLHPTPSTAPGPHVP----LM 470
                 PPP   P  PPP +   SP+ V +   PP   S L P P  +P    P    L 
Sbjct: 637 ------PPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLS 690

Query: 471 PP------SPPSQVIPASEP 484
           PP      SPP +  PAS P
Sbjct: 691 PPPEDSPTSPPPEDSPASPP 710



 Score = 82.8 bits (203), Expect = 8e-16
 Identities = 78/225 (34%), Positives = 95/225 (42%), Gaps = 43/225 (19%)

Query: 305 ENRPQSPATGRTPVFVSP-----TPPP---PPPPLPSALSTSSLRASMTSTPPPPVPPPP 356
           E  P SP    +P    P     +PPP   P  PLP AL  S        +PPP   P  
Sbjct: 445 EESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLS 504

Query: 357 PPPATA-----LQAPAVPP---PPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARA--APV 406
           PPP ++      ++P  PP   PP+P    P     +PPP A PL   SPP   +  +P 
Sbjct: 505 PPPESSPFSPLEESPLSPPEESPPSPALETP----LSPPPEASPL---SPPFEESPLSPP 557

Query: 407 CETVPVHPLPQGEVQGLPPPPPPPPL-PPPGIRPSSPVTVTALAHPP---SGLHPTPSTA 462
            E +P  P P  E   L PPP   P+ PPP   P SP    +   PP   S L P P  +
Sbjct: 558 PEELPTSPPP--EASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEES 615

Query: 463 PGPHVP----LMPP------SPPSQVIPASEPKR--HPSTLPVIS 495
           P    P    L PP      SPP +  P S P      S LPV+S
Sbjct: 616 PLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVS 660



 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 93/359 (25%), Positives = 126/359 (35%), Gaps = 101/359 (28%)

Query: 255  LPFSQMSELLTRAE-ERVLVRPHEP---PPPPPMHGAGDAK-------PIPTCISSATGL 303
            LP  +  +L  R+E   +  RP EP   P P   H +  A+       P   C+ +    
Sbjct: 726  LPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEE 785

Query: 304  IENRPQSPATGRTPV-------------FVSPTPPPP---PPPLPSALSTSSLRASMTST 347
                PQ+     +P               +SP P  P   P P  S LS  S    ++  
Sbjct: 786  PHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPR 845

Query: 348  P-----------PPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQP 396
            P           PP  P P  PP    Q PA  P   PL   PG    +P    P L +P
Sbjct: 846  PEESHLSPELEKPPLSPRPEKPPEEPGQCPA--PEELPLFPPPGEPSLSPLLGEPALSEP 903

Query: 397  SPPVARAAPVCETVPVHPL--PQGEVQGLPPPPPPPPL-------PPPGIRP-------- 439
              P    +P+ E +P+ P   P    Q +PP P PPPL        PP + P        
Sbjct: 904  GEPPL--SPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPF 961

Query: 440  ------------SSPVTVTALAHPPSG------------LHPTPSTAPGPHVPL----MP 471
                        ++P+  T ++ PP              L P+P +  GP  P+    +P
Sbjct: 962  GAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLP 1021

Query: 472  P--------------SPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEE 516
            P              SPPSQ  P + P   PS L  I     V  EA    ++  KV E
Sbjct: 1022 PQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSE 1080



 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 73/246 (29%), Positives = 89/246 (36%), Gaps = 44/246 (17%)

Query: 256 PFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGR 315
           P  + S L    E+  +  P E  P  P        P+P  +S  +   E  P SP    
Sbjct: 619 PPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPV-VSRLSPPPEESPLSP---- 673

Query: 316 TPVFVSPTPPPP------PPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVP 369
            P   SPT PPP      PPP            S TS PP   P  PPP  + +  P   
Sbjct: 674 -PPEESPTSPPPEASRLSPPP----------EDSPTSPPPEDSPASPPPEDSLMSLPLEE 722

Query: 370 PPPAPLQIAPGVL------HPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGL 423
            P  PL   P +       H +P P  P L  P P     +P  E    H  PQ E   L
Sbjct: 723 SPLLPLPEEPQLCPRSEGPHLSPRPEEPHL-SPRPEEPHLSPQAE--EPHLSPQPEEPCL 779

Query: 424 PPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPST-----APGPHVPLMPPSP-PSQ 477
              P  P L P    P        L+  P  LH +P T     +P P  P + P P  S 
Sbjct: 780 CAVPEEPHLSPQAEGPH-------LSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESH 832

Query: 478 VIPASE 483
           + P SE
Sbjct: 833 LSPQSE 838



 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 92/334 (27%), Positives = 119/334 (35%), Gaps = 49/334 (14%)

Query: 190 PEKVPRAPHDRRREWQK-LAQGPELAEDDANLLHKHIEVANGPASHFETRPQTYVDHMDG 248
           PE++P +P        + L + P     + + L    E  + P S  E  P +  +    
Sbjct: 471 PEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPE--SSPFSPLEESPLSPPEESPP 528

Query: 249 SYSLSA--LPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSATGLIEN 306
           S +L     P  + S L    EE  L  P E  P  P   A    P P   S  +   E 
Sbjct: 529 SPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPE-ESPMSPPPEE 587

Query: 307 RPQSPATGRTPVFV----SPTPPPP------PPPLPSALSTSSLRASMTSTPP--PPVPP 354
            P SP    + +F     SP  PPP      PPP  S LS     + M+  P   P  PP
Sbjct: 588 SPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPP 647

Query: 355 P---------------PPPPATAL-----QAPAVPPPPAPLQIAPGVLHPAPPPIAPPLV 394
           P               PPP  + L     ++P  PPP A     P    P  PP      
Sbjct: 648 PEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPA 707

Query: 395 QPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSG 454
            P P  +  +   E  P+ PLP  E   L P    P L P   RP  P     L+  P  
Sbjct: 708 SPPPEDSLMSLPLEESPLLPLP--EEPQLCPRSEGPHLSP---RPEEP----HLSPRPEE 758

Query: 455 LHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHP 488
            H +P  A  PH+   P  P    +P  EP   P
Sbjct: 759 PHLSPQ-AEEPHLSPQPEEPCLCAVP-EEPHLSP 790



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 78/269 (28%), Positives = 95/269 (35%), Gaps = 64/269 (23%)

Query: 275  PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGR------------------T 316
            P   PPPP    A   + +P   S     +   PQS ++ +                  T
Sbjct: 2385 PRPQPPPPESCCALPPRSLP---SDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVT 2441

Query: 317  PVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPP----- 371
            P F SP P   PP  P          S     P   PP P PP  A +A ++        
Sbjct: 2442 PRFQSPDPYSRPPSRPQ---------SRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAG 2492

Query: 372  --PAPLQIAP-GVLHPAPPPIAPPLVQPSPP----VARAAPVCETVPVHPLPQGEVQGLP 424
              PA L   P G LH   P   PP    SP     V   +P+  T    P   GE   L 
Sbjct: 2493 GFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFT---FPQAVGE-PSLK 2548

Query: 425  PPPPPPPLPPP-------------GIRPSSPVTVTALAHPPSGLHPTPST-APGPHVPLM 470
            PP P P LPPP             G   S+  TV      PSG    PS+ + G    L 
Sbjct: 2549 PPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLS 2608

Query: 471  PPSPPSQVIPASEPKRHPSTLPVISDARS 499
            P  PPS V+P   P     +LP +S   S
Sbjct: 2609 PLRPPS-VLPPPAP---DGSLPYLSHGAS 2633



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 61/192 (31%), Positives = 72/192 (37%), Gaps = 23/192 (11%)

Query: 308  PQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATAL---- 363
            PQ  A G  P   +PT     P  P+ LSTS+        P   VP P  P    L    
Sbjct: 2108 PQPGALGSPPPAAAPTIFIGSPTTPAGLSTSA--DGFLKPPAGSVPGPDSPGELFLKLPP 2165

Query: 364  QAPAVPPPPAPLQIAPGV----LHPAPPPIAPPLVQPSPPVARAAPVCETVPVHP--LPQ 417
            Q PA  P   P  +AP        P  PP  PP   PSP  A A P        P     
Sbjct: 2166 QVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPP--YPSPTGAPAQPPMLGASSRPGAGQP 2223

Query: 418  GEVQGLPPPPP--PPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPG-PHVPLMPPSP 474
            GE    PP  P   P  P P ++P  P ++  LA P S     P    G    PL+ P P
Sbjct: 2224 GEFHTTPPGTPRHQPSTPDPFLKPRCP-SLDNLAVPES-----PGVGGGKASEPLLSPPP 2277

Query: 475  PSQVIPASEPKR 486
              +   A E K+
Sbjct: 2278 FGESRKALEVKK 2289



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 79/298 (26%), Positives = 110/298 (36%), Gaps = 59/298 (19%)

Query: 211  PELAEDDANLLH-----KHIEVANGPASHFETRPQTYVDHMDGSYSLSALPFSQMSELLT 265
            P   +   +LLH      H ++ +G +S   + P         S SL   P S M++ L 
Sbjct: 4098 PGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQP---SVSLGDQPGS-MTQNLL 4153

Query: 266  RAEERVLVRPHE------PPPPPPMHGAGDAKP----IPTC---ISSATGLIENRPQSPA 312
              ++ +L RP +      PP P P+  +G   P    +PT     +   G++   PQ   
Sbjct: 4154 GPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQ--- 4210

Query: 313  TGRTPVFVSPTPPPPPPPLPSALSTSSLRASMT--STPPPPVPPPPPPPATAL-----QA 365
                   +    P     L + L    L+ S     TPP   P     P   L     Q 
Sbjct: 4211 -------LRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQL 4263

Query: 366  PAVP-PPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLP 424
               P P   PLQ     L   P P  PP + P+PP A             L  G V G  
Sbjct: 4264 GGFPGPQTGPLQ----ELGAGPRPQGPPRL-PAPPGA-------------LSTGPVLGPV 4305

Query: 425  PPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPAS 482
             P PPP  P    RPS   + ++     + L PT    P P  P + P PP +V PA+
Sbjct: 4306 HPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEP-PPGRVSPAA 4362



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 65/257 (25%), Positives = 78/257 (30%), Gaps = 53/257 (20%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSP------TPPPPPPPL 331
            PP   P    G         +SA G ++     P  G  P   SP       PP  P  +
Sbjct: 2117 PPAAAPTIFIGSPTTPAGLSTSADGFLK-----PPAGSVPGPDSPGELFLKLPPQVPAQV 2171

Query: 332  PS----ALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPP 387
            PS     L+ +        T PP  PP P P     Q P +     P    PG  H  PP
Sbjct: 2172 PSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPP 2231

Query: 388  PIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPP------------ 435
                P  QPS P     P C ++    +P+    G      P   PPP            
Sbjct: 2232 --GTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKK 2289

Query: 436  ----GIRPS-SPVTVTALAHPPSGLH------PTPSTAPGPHVP-------------LMP 471
                   PS  P  +  +  P SG H       TP     P  P             L P
Sbjct: 2290 EELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRP 2349

Query: 472  PSPPSQVIPASEPKRHP 488
              PP     A  P  HP
Sbjct: 2350 QEPPPAQALAPSPPSHP 2366



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 48/160 (30%), Positives = 60/160 (37%), Gaps = 25/160 (15%)

Query: 259  QMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQ-----SPAT 313
            Q  +L     +R L +       PP    G      T  S   GL+  +PQ      P T
Sbjct: 4218 QQQQLQALLMQRQLQQSQAVRQTPPYQEPG------TQTSPLQGLLGCQPQLGGFPGPQT 4271

Query: 314  GRTPVF-VSPTPPPPP--PPLPSALSTSSLRASMTSTPPPPVPPPP------PPPATALQ 364
            G        P P  PP  P  P ALST  +   +  TPPP  P  P      P P++ L 
Sbjct: 4272 GPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLP 4331

Query: 365  APAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAA 404
              A  PP  P     G   P  P + PP  + SP  A+ A
Sbjct: 4332 TEAQLPPTHP-----GTPKPQGPTLEPPPGRVSPAAAQLA 4366



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 66/243 (27%), Positives = 85/243 (34%), Gaps = 30/243 (12%)

Query: 276  HEPPPPPPMHGAGDAKPI--PTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPS 333
            H  PP  P H      P   P C S     +   P+SP  G          PPP      
Sbjct: 2227 HTTPPGTPRHQPSTPDPFLKPRCPSLDNLAV---PESPGVGGGKASEPLLSPPPFGESRK 2283

Query: 334  ALSTSS--LRASMTSTPPPPVPPPPPPPATA------LQAPAV---PPPPAPLQI---AP 379
            AL      L AS  S  PP +     P +        L+ P V   P  P   Q+   +P
Sbjct: 2284 ALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSP 2343

Query: 380  GV-LHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPP-----LP 433
            G+ L P  PP A  L  PSPP   + P       +  P  +    P P PPPP     LP
Sbjct: 2344 GLGLRPQEPPPAQALA-PSPP---SHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALP 2399

Query: 434  PPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLPV 493
            P  + PS P +    +        +P T          PSP +    + +P   P + P 
Sbjct: 2400 PRSL-PSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQ 2458

Query: 494  ISD 496
              D
Sbjct: 2459 SRD 2461



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 31/85 (36%), Positives = 40/85 (47%), Gaps = 6/85 (7%)

Query: 323  TPPPPPPPLPS-ALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGV 381
            +P P PP   S   + S+L     S PPP  P PPP P     +PA PP    +++    
Sbjct: 4883 SPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLA--PSPASPPTEPLVELPTEP 4940

Query: 382  LHPAPPPIAPPL-VQPSPPVARAAP 405
            L  A PP+  PL +  SP  AR  P
Sbjct: 4941 L--AEPPVPSPLPLASSPESARPKP 4963



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 55/198 (27%), Positives = 68/198 (34%), Gaps = 28/198 (14%)

Query: 308  PQSPATGRTPVFVSPTPPPPPPPLPSALSTSSL-RASMTSTP---PPPVPPPPPPPATAL 363
            PQSP  G  P      PPP     PS  S   + R    + P   PP  P P PPP  + 
Sbjct: 2340 PQSPGLGLRP----QEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESC 2395

Query: 364  QAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGL 423
             A     PP  L   P    PA P        P  P   +A      PV P  Q      
Sbjct: 2396 CA----LPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQS----- 2446

Query: 424  PPPPPPPPLPPPGIRPSSPVTVTALAHPP-----SGLHPTPSTAPGPHVPLMPPSPPSQV 478
            P P   PP  P    P +P+       PP     +G     S   G     +P  P  ++
Sbjct: 2447 PDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGEL 2506

Query: 479  ---IPASEPK---RHPST 490
               +P+ +P    R P T
Sbjct: 2507 HAKVPSGQPPNFVRSPGT 2524



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 72/270 (26%), Positives = 87/270 (32%), Gaps = 66/270 (24%)

Query: 282  PPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPL------PSAL 335
            PP   A      P  ++ A  L    P +P T   P + SPT  P  PP+      P A 
Sbjct: 2164 PPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPT--YPPYPSPTGAPAQPPMLGASSRPGAG 2221

Query: 336  STSSLRASMTSTP------PPPVPPPPPPPATALQAPAVP-------------PPP---- 372
                   +   TP      P P   P  P    L  P  P             PPP    
Sbjct: 2222 QPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGES 2281

Query: 373  -APLQIAPGVLHPAPPPIAPP----------------LVQPSPPVARAAPVCETVPVHPL 415
               L++    L  + P   PP                L   +P V +A        V P 
Sbjct: 2282 RKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQ 2341

Query: 416  PQGEVQGLPPPPPPP-----PLPP--PGI-RPSSPVTVTALAHPPSGLHPTPSTAPGPHV 467
              G   GL P  PPP     P PP  P I RP S       A PP  L P P   P    
Sbjct: 2342 SPG--LGLRPQEPPPAQALAPSPPSHPDIFRPGS--YTDPYAQPP--LTPRPQPPPPESC 2395

Query: 468  PLMP----PSPPSQVIPASEPKRHPSTLPV 493
              +P    PS P   +PAS   +  S  P+
Sbjct: 2396 CALPPRSLPSDPFSRVPASPQSQSSSQSPL 2425



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 25/74 (33%), Positives = 30/74 (40%), Gaps = 14/74 (18%)

Query: 390  APPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALA 449
            APP  +PSPP +  AP   + P  PL +   + L  PP P PLP              LA
Sbjct: 4908 APPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLP--------------LA 4953

Query: 450  HPPSGLHPTPSTAP 463
              P    P P   P
Sbjct: 4954 SSPESARPKPRARP 4967



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 28/88 (31%), Positives = 36/88 (40%), Gaps = 3/88 (3%)

Query: 308  PQSPATGRTPVFVSPTPPPPPPP---LPSALSTSSLRASMTSTPPPPVPPPPPPPATALQ 364
            P + +TG     V PTPPP  P     PS L + S +    +  PP  P  P P    L+
Sbjct: 4293 PGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLE 4352

Query: 365  APAVPPPPAPLQIAPGVLHPAPPPIAPP 392
             P     PA  Q+A  +      P  PP
Sbjct: 4353 PPPGRVSPAAAQLADTLFSKGLGPWDPP 4380



 Score = 37.0 bits (84), Expect = 0.048
 Identities = 63/264 (23%), Positives = 83/264 (31%), Gaps = 79/264 (29%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            P  PPP     D +P+P  I      +   P SP    +P+ + P PP   P L  +L  
Sbjct: 981  PISPPPEANCTDPEPVPPMI------LPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVP 1034

Query: 338  SSLRASMTSTP------PPPVPP-----------------------------------PP 356
             +   S  S P      P P+ P                                   P 
Sbjct: 1035 QNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPL 1094

Query: 357  PPPATALQAPAVPPPPAPLQIAPGVLHPAPP--PIAPPLVQPSP--------PVARAAPV 406
            P P   L  PA  P PA L    G+     P   I  P  QP P           + +PV
Sbjct: 1095 PSPMGDLSCPAPSPAPA-LDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPV 1153

Query: 407  C----ETVPVHPL------PQGEVQGLP------PPPPPPPLPPPGIRPSSPVTVTALAH 450
                 E  PV P+       Q   QG P      P  P  P PP  I+      ++ L+ 
Sbjct: 1154 LLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQ 1213

Query: 451  PPSGLHPTPSTAPGPHVPLMPPSP 474
              +      ++ PG    L  P P
Sbjct: 1214 GDAS-----ASFPGSEPLLGSPDP 1232



 Score = 37.0 bits (84), Expect = 0.048
 Identities = 24/73 (32%), Positives = 29/73 (39%), Gaps = 11/73 (15%)

Query: 320  VSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAP 379
            +S  PP  P P PS L+           P P  PP  P      +  A PP P+PL +A 
Sbjct: 4906 LSAPPPEEPSPPPSPLA-----------PSPASPPTEPLVELPTEPLAEPPVPSPLPLAS 4954

Query: 380  GVLHPAPPPIAPP 392
                  P P A P
Sbjct: 4955 SPESARPKPRARP 4967



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 59/204 (28%), Positives = 73/204 (35%), Gaps = 59/204 (28%)

Query: 306  NRPQSPAT------------GRTPVFVSPTPPPPPPPLPS----------ALSTSSLRAS 343
            +RP  PAT            G +  F    P P   PL            A + +S+R +
Sbjct: 2773 SRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFA 2832

Query: 344  MT----STPPPPVP-----PPPPPPATALQAPA--VPPPPAPLQIAPGVLHPAPPPIAP- 391
            M+    STP P +       P    +T L  P   VP P  P Q    + H     + P 
Sbjct: 2833 MSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIE-LRHNVQKGLGPG 2891

Query: 392  --PLVQPSPPVA-RAAPVCETVPVHPLPQG----EVQGLPPPPPPPPLPPPGIRPSSPVT 444
              P     PP   R  PV E  P    P+G     V GLPP  P  P P P +  S    
Sbjct: 2892 GTPFPGQGPPQRPRFYPVSED-PHRLAPEGLRGLAVSGLPPQKPSAP-PAPELNNS---- 2945

Query: 445  VTALAHPPSGLHPTPSTAPGPHVP 468
                      LHPTP T  GP +P
Sbjct: 2946 ----------LHPTPHT-KGPTLP 2958



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 37/161 (22%), Positives = 60/161 (37%), Gaps = 5/161 (3%)

Query: 377  IAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPG 436
            + PG    +   I   L Q SP          T  V  L   ++   PP  P PP  P  
Sbjct: 4863 VLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLA 4922

Query: 437  IRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEP--KRHPSTLPVI 494
              P+SP T   +  P   L   P  +P   +PL      ++  P + P  +   S  P +
Sbjct: 4923 PSPASPPTEPLVELPTEPLAEPPVPSP---LPLASSPESARPKPRARPPEEGEDSRPPRL 4979

Query: 495  SDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATIL 535
               + V  + +R  + ++K   ++E E +       + T L
Sbjct: 4980 KKWKGVRWKRLRLLLTIQKGSGRQEDEREVAEFMEQLGTAL 5020



 Score = 32.7 bits (73), Expect = 0.90
 Identities = 36/129 (27%), Positives = 47/129 (36%), Gaps = 8/129 (6%)

Query: 286  GAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPP--PL---PSALSTSSL 340
            G G+  P P   +    L  N  +    G TP F    PP  P   P+   P  L+   L
Sbjct: 2863 GPGEPVPGPAGPAQFIELRHNVQKGLGPGGTP-FPGQGPPQRPRFYPVSEDPHRLAPEGL 2921

Query: 341  RASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPV 400
            R    S  PP  P  PP P         P    P  +  G+     PP +  L +P+P  
Sbjct: 2922 RGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGP-TLPTGLELVNRPPSSTELGRPNPLA 2980

Query: 401  ARAAPV-CE 408
              A  + CE
Sbjct: 2981 LEAGKLPCE 2989



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 25/84 (29%), Positives = 27/84 (32%), Gaps = 17/84 (20%)

Query: 275  PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSA 334
            P EP PPP       A P        T  +   P  P             PP P PLP A
Sbjct: 4911 PEEPSPPPSPLAPSPASP-------PTEPLVELPTEPLA----------EPPVPSPLPLA 4953

Query: 335  LSTSSLRASMTSTPPPPVPPPPPP 358
             S  S R    + PP       PP
Sbjct: 4954 SSPESARPKPRARPPEEGEDSRPP 4977



 Score = 30.4 bits (67), Expect = 4.5
 Identities = 22/55 (40%), Positives = 24/55 (43%), Gaps = 7/55 (12%)

Query: 324  PPPPPPPL-PSALSTSSLRASMTSTPP---PPVPPPPP---PPATALQAPAVPPP 371
            P PPP PL PS  S  +       T P   PPVP P P    P +A   P   PP
Sbjct: 4914 PSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPP 4968



 Score = 30.0 bits (66), Expect = 5.8
 Identities = 46/188 (24%), Positives = 64/188 (34%), Gaps = 25/188 (13%)

Query: 326  PPPPPLPSALSTSSLR---ASMTSTPPPPVPPPPP--------------PPATALQ---A 365
            PPPP  PS++  +S +    S       P P   P                AT+++   +
Sbjct: 2775 PPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMS 2834

Query: 366  PAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPP 425
               P  P P ++    L      I+  L  P  PV   A   + + +    Q   +GL P
Sbjct: 2835 ARFPSTPGP-ELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQ---KGLGP 2890

Query: 426  PPPPPPLPPPGIRPSS-PVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEP 484
               P P   P  RP   PV+       P GL     +   P  P  PP+P         P
Sbjct: 2891 GGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTP 2950

Query: 485  KRHPSTLP 492
                 TLP
Sbjct: 2951 HTKGPTLP 2958



 Score = 30.0 bits (66), Expect = 5.8
 Identities = 20/68 (29%), Positives = 25/68 (36%), Gaps = 1/68 (1%)

Query: 322  PTPPPPPPPLPSALSTSSLRAS-MTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPG 380
            P   P PPP P A S +S     +   P  P+  PP P    L +      P P    P 
Sbjct: 4910 PPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPE 4969

Query: 381  VLHPAPPP 388
                + PP
Sbjct: 4970 EGEDSRPP 4977


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
            sapiens]
          Length = 1362

 Score = 85.9 bits (211), Expect = 9e-17
 Identities = 88/282 (31%), Positives = 106/282 (37%), Gaps = 72/282 (25%)

Query: 278  PPPPPPMHGAGDAKPI-----PTCISSATGLIENRPQSPATGRTPV--FVSPT------- 323
            PPPPPP      A P      P  I++   ++E  PQ P +   P+  F  P        
Sbjct: 777  PPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLE--PQLPGSVFDPIGHFTQPILHLPQPE 834

Query: 324  -----PPPP---------------PPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATAL 363
                 P PP               PP L +AL     R S  +   PP P  PP  + AL
Sbjct: 835  LPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPAL 894

Query: 364  -QAPAVPPPPAPLQIAPGVLHPAPPPIAPPL--------------VQPSPP------VAR 402
             Q P +P P  P+   P VL     P APPL              VQP  P      V  
Sbjct: 895  TQTPLLPQP--PMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQS 952

Query: 403  AAPVCETVPVHPLPQGEVQGLPPPPPPP-PLPPPGIR---PSSPVTVTALAH-------- 450
              P     P HP  Q ++Q  PPPPPPP P PPP  +   P  PV +  +          
Sbjct: 953  QPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPP 1012

Query: 451  PPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLP 492
            PP G  P P   PG   P   P+ P QVI      RH  + P
Sbjct: 1013 PPQGQQP-PHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDP 1053



 Score = 80.1 bits (196), Expect = 5e-15
 Identities = 67/209 (32%), Positives = 85/209 (40%), Gaps = 42/209 (20%)

Query: 321 SPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPA-PLQIAP 379
           +P P P  PP                 PPP  PPPPPPP    Q P  PPPP+ P Q AP
Sbjct: 749 APAPVPQQPP-----------------PPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAP 791

Query: 380 GVLHPAPPPIAP--PLVQPSPPVARAAPVCE-TVPVHPLPQGEVQGLPP--PPPPPPLPP 434
            +    PP IA   P+++P  P +   P+   T P+  LPQ E   LPP  P PP    P
Sbjct: 792 AMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPE---LPPHLPQPPEHSTP 848

Query: 435 PGIRP----SSPVTVTALAHPPS-------GLHPTPSTAPG-----PHVPLMPPSPPSQV 478
           P +      S P    AL   PS        L P P+  P         PL+P  P +Q 
Sbjct: 849 PHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQP 908

Query: 479 IPASEPKRHPSTLPVISDARSVLLEAIRK 507
                    P   P+ S    + L+ ++K
Sbjct: 909 PQVLLEDEEPPAPPLTSMQMQLYLQQLQK 937



 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 76/257 (29%), Positives = 95/257 (36%), Gaps = 63/257 (24%)

Query: 276  HEPPPPPPMHGAGDAKPI-PTCISSATGLIENRPQ--SPATGRTPVFVSPT---PP---- 325
            H    PP +H A   +P  P+  ++A      RP   SPA  +TP+   P    PP    
Sbjct: 854  HAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLL 913

Query: 326  ----PPPPPLPSALSTSSLR--------------ASMTSTPPPPVPPPPPPPATAL--QA 365
                PP PPL S      L+                + S PPPP+PPPP P       Q 
Sbjct: 914  EDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQ 973

Query: 366  PAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPP 425
            P  PPPP           P PPP       P P   +       +   P PQG+     P
Sbjct: 974  PPPPPPP----------QPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQ----QP 1019

Query: 426  PPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPST------APGP---HVPLMP----- 471
            P PPP   PP  +P+ P  V    H P      P +      AP P   H P M      
Sbjct: 1020 PHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSL 1079

Query: 472  --PSPPSQVIPASEPKR 486
               SPP Q +   +PK+
Sbjct: 1080 THQSPPQQNV---QPKK 1093



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 50/177 (28%), Positives = 67/177 (37%), Gaps = 24/177 (13%)

Query: 288 GDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPP---PPPPLPSALSTSSLRASM 344
           G AKP  + + + T     +  +P   +TP    P PPP    P P P A++   +  + 
Sbjct: 187 GTAKPGVSTVPNTT-----QASTPPQTQTP---QPNPPPVQATPHPFP-AVTPDLIVQTP 237

Query: 345 TSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAA 404
             T  PP P   PPP      P   P P P+Q  P ++   P P     V+    V R A
Sbjct: 238 VMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQP-----VKTKKGVKRKA 292

Query: 405 PVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIR--PSSPVTVTALAHPPSGLHPTP 459
                  + P+ +      P  PP P     G R   S PV       P S  HP P
Sbjct: 293 DTTTPTTIDPIHEP-----PSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAP 344



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 39/121 (32%), Positives = 44/121 (36%), Gaps = 33/121 (27%)

Query: 375 LQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPL-- 432
           +Q AP  +   PPP   P  QP PP              P PQ + Q  PPPPPPP +  
Sbjct: 746 MQQAPAPVPQQPPP---PPQQPPPP--------------PPPQQQQQP-PPPPPPPSMPQ 787

Query: 433 ---------PPPGIRPSSPVTVTAL---AHPPSGLHPTPST-APGPHVPLMPPSPPSQVI 479
                    PPP I    PV    L      P G    P    P P +P   P PP    
Sbjct: 788 QAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHST 847

Query: 480 P 480
           P
Sbjct: 848 P 848



 Score = 37.4 bits (85), Expect = 0.037
 Identities = 23/70 (32%), Positives = 29/70 (41%), Gaps = 6/70 (8%)

Query: 419 EVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQV 478
           ++Q  P P P  P PPP   P  P        PP    P P + P    P M  SPP  +
Sbjct: 745 QMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPP---PPPPSMPQQAAPAMKSSPPPFI 801

Query: 479 ---IPASEPK 485
              +P  EP+
Sbjct: 802 ATQVPVLEPQ 811



 Score = 34.3 bits (77), Expect = 0.31
 Identities = 28/88 (31%), Positives = 33/88 (37%), Gaps = 9/88 (10%)

Query: 403 AAPVCETVPVHPLPQGEVQGLPPPPPPPPL-----PPPGIRPSSPV-TVTALAHPPSGLH 456
           A P   TVP         Q   P P PPP+     P P + P   V T      PP  L 
Sbjct: 189 AKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQ 248

Query: 457 PTPSTAPGPHVPLMPPSPPSQVIPASEP 484
             P   P P  P  PP+P  Q + +  P
Sbjct: 249 TPP---PVPPQPQPPPAPAPQPVQSHPP 273



 Score = 33.1 bits (74), Expect = 0.69
 Identities = 29/103 (28%), Positives = 38/103 (36%), Gaps = 13/103 (12%)

Query: 274 RPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGR---------TPVFVSPTP 324
           +P + PPP P        P P  + S   +I   PQ   T +         TP  + P  
Sbjct: 245 QPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIH 304

Query: 325 PPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPA 367
            PP   LP    T+ L     S+   PV PP      + Q PA
Sbjct: 305 EPPS--LPPEPKTTKLGQRRESS--RPVKPPKKDVPDSQQHPA 343



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 26/91 (28%), Positives = 31/91 (34%), Gaps = 7/91 (7%)

Query: 390 APPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALA 449
           A P V   P   +A+    T P    PQ     +   P P P   P +   +PV      
Sbjct: 189 AKPGVSTVPNTTQAS----TPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVV-- 242

Query: 450 HPPSGLHPTPSTAPGPHVPLMPPSPPSQVIP 480
            PP  L   P   P P  P  P   P Q  P
Sbjct: 243 -PPQPLQTPPPVPPQPQPPPAPAPQPVQSHP 272


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 83.6 bits (205), Expect = 4e-16
 Identities = 74/247 (29%), Positives = 101/247 (40%), Gaps = 27/247 (10%)

Query: 322  PTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPP----PPPATALQAPAVPPPPAPLQI 377
            P PPPP     +   T   R +     PP +PPPP    PPP      P +PPP    + 
Sbjct: 1161 PEPPPPLSVYHNGTGTVRRRPASEQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEAR- 1219

Query: 378  APGVLHPAPPPIAPP--LVQPSPPV-ARAAPVCETVPVHPLPQGEVQ---GLPPPPPPPP 431
                  PA PP++P   L QP P +     P  + VP+      EV+   G PPP  P P
Sbjct: 1220 -----KPAKPPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKP 1274

Query: 432  LPPPGIRPSSPVTVTALAHPPSGL---HPTPSTAPGPHVPLMPP--SPPS-QVIPASEPK 485
             PP    P++P  V A+A  PSG     P PS A  P   L  P  +PPS    PA  P 
Sbjct: 1275 PPP----PTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPS 1330

Query: 486  RHPSTLPV-ISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIAVEYS 544
                 L V     R+    A          E     ++  +++E   A + +   AVE  
Sbjct: 1331 PGAPALHVPAKPPRAAAAAAAAAAAPPAPPEGASPGDSARQKLEETSACLAAALQAVEEK 1390

Query: 545  DSEDDSE 551
              ++D++
Sbjct: 1391 IRQEDAQ 1397



 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 80/264 (30%), Positives = 97/264 (36%), Gaps = 50/264 (18%)

Query: 277  EPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALS 336
            EPPPP  ++  G            TG +  RP S   G   +   P PPPP  P P+ L 
Sbjct: 1162 EPPPPLSVYHNG------------TGTVRRRPASEQAGPPEL---PPPPPPAEPPPTDL- 1205

Query: 337  TSSLRASMTSTPPP------PVPPPPPP------PATALQAPAVP-----PPPAPLQIAP 379
                 A +   PPP      P  PP  P      P   LQ    P     P P P     
Sbjct: 1206 -----AHLPPLPPPEGEARKPAKPPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEV 1260

Query: 380  GVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRP 439
               H  PPP++P   +P PP     PV     V  LP G     P P P P   PP    
Sbjct: 1261 KRAHGTPPPVSP---KPPPPPTAPKPV---KAVAGLPSGSAG--PSPAPSPARQPPAALA 1312

Query: 440  SSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPP-SPPSQVIPASEPKRHPSTLPVISDAR 498
              P T  +L   P+   P    AP  HVP  PP +  +    A+ P   P        AR
Sbjct: 1313 KPPGTPPSLGASPA--KPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAPPEGASPGDSAR 1370

Query: 499  SVLLE-AIRKGIQLRKVEEQREQE 521
              L E +      L+ VEE+  QE
Sbjct: 1371 QKLEETSACLAAALQAVEEKIRQE 1394



 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 72/262 (27%), Positives = 92/262 (35%), Gaps = 57/262 (21%)

Query: 275  PHEPPPPPPMHGAGDAKPIPTCISSATGL-----IENRPQSPATGRTPVFV--------S 321
            P E PPPPP      A+P PT ++    L        +P  P     PV          S
Sbjct: 1188 PPELPPPPP-----PAEPPPTDLAHLPPLPPPEGEARKPAKPPVSPKPVLTQPVPKLQGS 1242

Query: 322  PTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGV 381
            PTP     PLP   S    RA  T   PPPV P PPPP TA         P P++   G+
Sbjct: 1243 PTPTSKKVPLPGPGSPEVKRAHGT---PPPVSPKPPPPPTA---------PKPVKAVAGL 1290

Query: 382  LHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSS 441
               +  P   P     PP A A P     P  P   G     PP P  P L  P   P +
Sbjct: 1291 PSGSAGPSPAPSPARQPPAALAKP-----PGTPPSLGASPAKPPSPGAPALHVPAKPPRA 1345

Query: 442  PVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDARSVL 501
                 A A                     PP+PP    P    ++    L   S   +  
Sbjct: 1346 AAAAAAAA-------------------AAPPAPPEGASPGDSARQ---KLEETSACLAAA 1383

Query: 502  LEAIRKGIQLRKVEEQREQEAK 523
            L+A+ + I+    +  R+  A+
Sbjct: 1384 LQAVEEKIRQEDAQGPRDSAAE 1405



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 71/278 (25%), Positives = 94/278 (33%), Gaps = 74/278 (26%)

Query: 263 LLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSP 322
           L  +A + + V   E PPPP    A    P  T    +   + +  Q+  TG  P  V P
Sbjct: 618 LRRKAPQSLEVMAIESPPPPEPTPADCQSPKMTTFQDSE--LSDELQAAMTG--PAEVGP 673

Query: 323 TP-------PPPP---------------------------PPLPSALSTSSLRASMTSTP 348
           T        PP P                           PP PS+  + S    +   P
Sbjct: 674 TTEKPSSHLPPTPRATTRQDSSLGGRARHMSSSQELLGDGPPGPSSPMSRSQEYLLDEGP 733

Query: 349 PPPVPPPPPPPAT---ALQAPAVPPPPA-PLQIAPGVLHPAPPPIAPPLVQPSPPVARAA 404
            P  PP    P     +++  +VPP P  P Q+ P       PP  P   +P  P A   
Sbjct: 734 APGTPPREARPGRHGHSIKRASVPPVPGKPRQVLPPGTSHFTPPQTPTKTRPGSPQALGG 793

Query: 405 PVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLH-------P 457
                      P G         P P L PP  RP SP ++     P S  H       P
Sbjct: 794 -----------PHGPAPATAKVKPTPQLLPPTERPMSPRSL-----PQSPTHRGFAYVLP 837

Query: 458 TP------STAPGPHVPLMPPSPPSQVIPA---SEPKR 486
            P        APGP  P +P + P+  +P    +EP R
Sbjct: 838 QPVEGEVGPAAPGPAPPPVPTAVPTLCLPPEADAEPGR 875



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 55/214 (25%), Positives = 69/214 (32%), Gaps = 33/214 (15%)

Query: 274 RPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPS 333
           +P +  PP   H      P  T   S   L      +PAT +    V PTP   PP    
Sbjct: 762 KPRQVLPPGTSHFTPPQTPTKTRPGSPQALGGPHGPAPATAK----VKPTPQLLPP---- 813

Query: 334 ALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPL 393
                        T  P  P   P   T      V P P   ++ P    PAPPP+  P 
Sbjct: 814 -------------TERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAPGPAPPPV--PT 858

Query: 394 VQPS---PPVARAAPVCETVPVHPL-------PQGEVQGLPPPPPPPPLPPPGIRPSSPV 443
             P+   PP A A P       H L        + E   L  P    P      R     
Sbjct: 859 AVPTLCLPPEADAEPGRPKKRAHSLNRYAASDSEPERDELLVPAAAGPYATVQRRVGRSH 918

Query: 444 TVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQ 477
           +V A A     ++ + S A  P     PP PP +
Sbjct: 919 SVRAPAGADKNVNRSQSFAVRPRKKGPPPPPPKR 952



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 54/200 (27%), Positives = 67/200 (33%), Gaps = 49/200 (24%)

Query: 275 PHEPPPPPPMHGAGDAKPIPTCISSATGLIENR--PQSPATGRTPVFVSP---------- 322
           PH P P          KP P  +      +  R  PQSP T R   +V P          
Sbjct: 794 PHGPAP-----ATAKVKPTPQLLPPTERPMSPRSLPQSP-THRGFAYVLPQPVEGEVGPA 847

Query: 323 TPPPPPPPLPSALSTSSLRASMTSTPPPP----------VPPPPPPPATALQAPAVPPPP 372
            P P PPP+P+A+ T  L     + P  P                P    L  PA   P 
Sbjct: 848 APGPAPPPVPTAVPTLCLPPEADAEPGRPKKRAHSLNRYAASDSEPERDELLVPAAAGPY 907

Query: 373 APLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPL 432
           A +Q   G  H    P           V R+    ++  V P  +G       PPPPPP 
Sbjct: 908 ATVQRRVGRSHSVRAPAGA-----DKNVNRS----QSFAVRPRKKG-------PPPPPP- 950

Query: 433 PPPGIRPSSPVTVTALAHPP 452
                R SS +    LA  P
Sbjct: 951 ----KRSSSALASANLADEP 966


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 82.8 bits (203), Expect = 8e-16
 Identities = 64/189 (33%), Positives = 77/189 (40%), Gaps = 27/189 (14%)

Query: 302 GLIENR-PQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPA 360
           GL +NR P  P  G++     P PP PPPP          +      PPP  PPP  PP 
Sbjct: 39  GLNQNRGPMGPGPGQS----GPKPPIPPPP-----PHQQQQQPPPQQPPPQQPPPHQPPP 89

Query: 361 TALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEV 420
                    PPP P   +  V+   P P   P V  +PP + +AP   T P    P G  
Sbjct: 90  HPQPHQQQQPPPPPQDSSKPVVAQGPGP--APGVGSAPPASSSAPPA-TPPTSGAPPGSG 146

Query: 421 QG-LPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVI 479
            G  P PPP     PPG  P +P        P SG+  TP  A GP     PP P +   
Sbjct: 147 PGPTPTPPPAVTSAPPGAPPPTP--------PSSGVPTTPPQAGGP-----PPPPAAVPG 193

Query: 480 PASEPKRHP 488
           P   PK+ P
Sbjct: 194 PGPGPKQGP 202



 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 51/165 (30%), Positives = 63/165 (38%), Gaps = 43/165 (26%)

Query: 347 TPPPPVP------PPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPV 400
           +PPP +       P  P P  +   P +PPPP      P      PPP  PP  QP P  
Sbjct: 33  SPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPP------PHQQQQQPPPQQPPPQQPPP-- 84

Query: 401 ARAAPVCETVPVHPLPQGEVQGLPPPPP-----------PPPLPPPGIRP----SSPVTV 445
                     P HP P  + Q  PPPPP           P P P  G  P    S+P   
Sbjct: 85  -------HQPPPHPQPHQQQQ--PPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPAT 135

Query: 446 TALAHPPSGLHPTPSTAPGPHVP-----LMPPSPPSQVIPASEPK 485
              +  P G  P P+  P P V        PP+PPS  +P + P+
Sbjct: 136 PPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQ 180



 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 62/215 (28%), Positives = 70/215 (32%), Gaps = 50/215 (23%)

Query: 275 PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSP----TPPPPPP- 329
           P  P PPPP H      P            +  PQ P   + P    P     PPPPP  
Sbjct: 56  PKPPIPPPPPHQQQQQPPPQ----------QPPPQQPPPHQPPPHPQPHQQQQPPPPPQD 105

Query: 330 ---------PLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPG 380
                    P P+    S+  AS  S+ PP  PP    P  +   P   PPPA     PG
Sbjct: 106 SSKPVVAQGPGPAPGVGSAPPAS--SSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPG 163

Query: 381 VLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPS 440
               APPP  P    P+ P     P                  PPPP   P P PG +  
Sbjct: 164 ----APPPTPPSSGVPTTPPQAGGP------------------PPPPAAVPGPGPGPKQG 201

Query: 441 SPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPP 475
                      P G  P P   PG   P   P PP
Sbjct: 202 PGPGGPKGGKMPGG--PKPGGGPGLSTPGGHPKPP 234



 Score = 33.1 bits (74), Expect = 0.69
 Identities = 36/137 (26%), Positives = 40/137 (29%), Gaps = 34/137 (24%)

Query: 357 PPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLP 416
           PPP   L     P  P P Q  P       PPI PP                  P H   
Sbjct: 34  PPPGMGLNQNRGPMGPGPGQSGP------KPPIPPP------------------PPHQQQ 69

Query: 417 QGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMP-PSPP 475
           Q          PPP  PPP   P          H      P P  +  P V   P P+P 
Sbjct: 70  Q---------QPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPG 120

Query: 476 SQVIPASEPKRHPSTLP 492
               P +     P+T P
Sbjct: 121 VGSAPPASSSAPPATPP 137


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 82.8 bits (203), Expect = 8e-16
 Identities = 67/194 (34%), Positives = 78/194 (40%), Gaps = 45/194 (23%)

Query: 297  ISSATGLIENRPQS-PATGRTPVFVSPTP------PPPPPPLPSALSTSSLRASMTSTPP 349
            ISSA   +++ P + P    TP      P      PPP P LPSA S  +    +    P
Sbjct: 1398 ISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKP 1457

Query: 350  PPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCET 409
            PP PPP P P      P  PPPP P Q A     P+PPP+  P   PS P          
Sbjct: 1458 PPTPPPAPTP-----QPQPPPPPPPPQPA----LPSPPPLVAP--TPSSP---------- 1496

Query: 410  VPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPL 469
             P  PLP       PPPPP  P PP    P  P     LA PP         AP P  P 
Sbjct: 1497 -PPPPLP-------PPPPPAMPSPP----PPPPPAAAPLAAPPE-----EPAAPSPEDPE 1539

Query: 470  MPPSPPSQVIPASE 483
            +P + P  +    E
Sbjct: 1540 LPDTRPLHLAKKQE 1553



 Score = 75.9 bits (185), Expect = 9e-14
 Identities = 48/126 (38%), Positives = 61/126 (48%), Gaps = 14/126 (11%)

Query: 279  PPPPPMHGAGDAKPIPTCISSATG----LIENRPQSPATGRTPVFVSPTPPPPPPPLPSA 334
            P PPP+ G      +P+  S+ T     L E  P +P    TP      PPPPPPP P+ 
Sbjct: 1431 PGPPPLPG------LPSANSNGTPEPPLLEEKPPPTPPPAPTPQ--PQPPPPPPPPQPAL 1482

Query: 335  LSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLV 394
             S   L A   S+PPPP  P PPPP  A+ +P  PPPPA   +A     PA P    P +
Sbjct: 1483 PSPPPLVAPTPSSPPPP--PLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPEL 1540

Query: 395  QPSPPV 400
              + P+
Sbjct: 1541 PDTRPL 1546



 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 55/168 (32%), Positives = 65/168 (38%), Gaps = 39/168 (23%)

Query: 319 FVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIA 378
           F+  +PPPPPP   S   T          P  P+  PPPPP                Q+ 
Sbjct: 759 FLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPP----------------QLL 802

Query: 379 PGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIR 438
           P VL  AP P               +P    V VH L      G P PPPPPP PPP   
Sbjct: 803 PSVLSHAPSP---------------SPSASKVGVHLLEPATRDGAPQPPPPPPPPPP--- 844

Query: 439 PSSPVTVTALAHPPS-GLHP-TPSTAPGPHVPLMPPSPPSQVIPASEP 484
              P+ +   AH  S GL P  PS    P   L PP    +++ A EP
Sbjct: 845 ---PMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEP 889



 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 67/247 (27%), Positives = 92/247 (37%), Gaps = 54/247 (21%)

Query: 282  PPMHGAGDAKPI--PTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPP---------- 329
            PP++ AG   P+  P  +  +      +PQ PAT        P  P PPP          
Sbjct: 1296 PPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPAT--------PAVPHPPPSGAFGLGGAL 1347

Query: 330  ------------PLPSALSTSSLRASMTSTPPPPVPPPPPPP---------ATALQAPAV 368
                        P P       L+ ++ + P                    ++A+ A   
Sbjct: 1348 EAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDD 1407

Query: 369  PPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCET--VPVHPLPQGEVQGLPPP 426
            PP   P   +     P  PP+AP    P PP     P   +   P  PL + +    PP 
Sbjct: 1408 PPLAGPKDTST----PDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKP---PPT 1460

Query: 427  PPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKR 486
            PPP P P P   P  P    AL  PP  + PTPS+ P P  PL PP PP+  +P+  P  
Sbjct: 1461 PPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPP--PLPPPPPPA--MPSPPPPP 1516

Query: 487  HPSTLPV 493
             P+  P+
Sbjct: 1517 PPAAAPL 1523



 Score = 69.3 bits (168), Expect = 9e-12
 Identities = 47/154 (30%), Positives = 62/154 (40%), Gaps = 22/154 (14%)

Query: 339  SLRASMTSTPPPPVPPPPP---PPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQ 395
            S+ +++++   PP+  P     P    L   A  P P PL   P       P   PPL++
Sbjct: 1397 SISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPE--PPLLE 1454

Query: 396  PSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGL 455
              PP         T P  P PQ      P PPPPPP P P +    P+     + PP   
Sbjct: 1455 EKPP--------PTPPPAPTPQ------PQPPPPPPPPQPALPSPPPLVAPTPSSPPPPP 1500

Query: 456  HPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPS 489
             P P   P P +P  PP PP    P + P   P+
Sbjct: 1501 LPPP---PPPAMPSPPPPPPPAAAPLAAPPEEPA 1531



 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 85/308 (27%), Positives = 96/308 (31%), Gaps = 115/308 (37%)

Query: 278  PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
            PPPPPP   A   +P P  +    G     P  P            PPPPP  LPS LS 
Sbjct: 764  PPPPPPT--AQSTQPTPHGLLLEAG----GPDLPLV---------LPPPPPQLLPSVLSH 808

Query: 338  SSL--------------RASMTSTPPPPVPPPPPPPATALQ----------APAVP---- 369
            +                 A+    P PP PPPPPPP   LQ           PA P    
Sbjct: 809  APSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRL 868

Query: 370  ------PPPAPLQIAPGVLHPAPPP-----IAPPLVQ----------PSPPVARA---AP 405
                   PP  +Q   G L P PP      + PP  +          PSP   +A    P
Sbjct: 869  RPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVP 928

Query: 406  VCETVPVHPLPQGEVQ--------------------------------GLPPPPPPPPLP 433
            +        L Q E +                                G  PPP PP   
Sbjct: 929  LTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYD 988

Query: 434  PPGIRPSSPVTVTALAHPPSGLHPT-----PSTA---------PGPH--VPLMPPSPPSQ 477
            P G       +      P  GL P      PST           GPH   P  PP PP  
Sbjct: 989  PYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPP 1048

Query: 478  VIPASEPK 485
              PASEPK
Sbjct: 1049 PAPASEPK 1056



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 60/225 (26%), Positives = 76/225 (33%), Gaps = 56/225 (24%)

Query: 275  PHEPPPPPPM----------HGAGDAKPIPT-----------CISSATGLIENRPQSP-- 311
            P  PPPPPPM          HG   A P P             +    G +E  P +P  
Sbjct: 837  PPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGD 896

Query: 312  -------ATGRTP--VFVSPTP----PPPPPPLPSALSTSSLRASMTSTPPPPV------ 352
                   + G+ P   + SP+P     P   PL S     SL      +  P +      
Sbjct: 897  TGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGG 956

Query: 353  -------PPPPPPPATALQAPAVPPPPAPL-----QIAPGVLHPAPPPIAPPLVQPSPPV 400
                      PP      +A A PPP  P         PG    A P      + P+ P 
Sbjct: 957  GAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPP 1016

Query: 401  ARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPP-PGIRPSSPVT 444
               + V    P+  +  G  Q  PPPPPPPP PP P   P   +T
Sbjct: 1017 ELPSTV-NAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLT 1060



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 60/220 (27%), Positives = 78/220 (35%), Gaps = 29/220 (13%)

Query: 284 MHGAGDAKPIPTCISSATGLIENRPQS--PATGRTPVFVSP-------TPPPPPPPLPSA 334
           +H AG A P  + ++  + L    PQ    A+     F SP       TP P    +  A
Sbjct: 76  LHHAGSAGPDASVMNLISALESRGPQPGPSASSLLSQFRSPSWQTAMHTPGPTELFISGA 135

Query: 335 LSTSSLRASMTSTPPPPVP------PPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPP 388
           L  SS   S ++      P      P P P + +LQ P   PP   L     VLH  P  
Sbjct: 136 LPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPS- 194

Query: 389 IAPPLVQPSPPVARAA--PVCETVPVHPLPQGEVQGLPPPPPPPPLPPP---GIRPSSPV 443
              P V  S    R A   V     + P      +  PP PPPPP   P    +  SS  
Sbjct: 195 -QAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSA 253

Query: 444 TVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASE 483
              A       L+     APG       P PP + +P  +
Sbjct: 254 AAAAAEQSSPQLYNFSGAAPG-------PPPPERALPRQD 286



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 32/92 (34%), Positives = 38/92 (41%), Gaps = 9/92 (9%)

Query: 274 RPHEP-PPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP 332
           RP  P PPPPP H       + +  ++A    ++ PQ         F    P PPPP   
Sbjct: 228 RPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYN------FSGAAPGPPPPE-- 279

Query: 333 SALSTSSLRASMTSTPPPPVPPPPPPPATALQ 364
            AL            P    PPPPPPPA ALQ
Sbjct: 280 RALPRQDTVIKHYQRPASAQPPPPPPPAHALQ 311



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 55/193 (28%), Positives = 70/193 (36%), Gaps = 39/193 (20%)

Query: 292 PIPTCISSATGLIENRPQSPATGR--TPVFVSPTPPPPPPPLPSALSTSSLRAS------ 343
           P+P+ +S     +++ P SP      +P  V    P   P +PS+L    L         
Sbjct: 163 PVPSSLS-----LQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPA 217

Query: 344 ---MTSTPP----PPVPPPPP---PPATALQAPAVPPPPAPLQIAPGVLH---PAPPPIA 390
                 TPP    PP PPPPP   P    L A +     A  Q +P + +    AP P  
Sbjct: 218 GLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGP-- 275

Query: 391 PPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPP----PGIRPSSPVTVT 446
                  PP  RA P  +TV  H       Q  PPPPP   L       G  PS      
Sbjct: 276 -------PPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRAN 328

Query: 447 ALAHPPSGLHPTP 459
               P  G  P+P
Sbjct: 329 LACSPLGGGEPSP 341



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 28/86 (32%), Positives = 33/86 (38%), Gaps = 15/86 (17%)

Query: 274  RPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPS 333
            +P  PPPPPP   A         + S   L+   P SP     P    P  P PPPP P 
Sbjct: 1468 QPQPPPPPPPPQPA---------LPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPP 1518

Query: 334  ALSTSSLRASMTSTPPPPVPPPPPPP 359
            A       A + + P  P  P P  P
Sbjct: 1519 A------AAPLAAPPEEPAAPSPEDP 1538



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 5/76 (6%)

Query: 322  PTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGV 381
            P   PP P   S  + + + A  +S PPP  P PPP P T  +  +  PP    +  P  
Sbjct: 1666 PWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPP----EQTPET 1721

Query: 382  LHPAPP-PIAPPLVQP 396
              P PP P  P L++P
Sbjct: 1722 AMPEPPAPEKPSLLRP 1737



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 56/210 (26%), Positives = 75/210 (35%), Gaps = 54/210 (25%)

Query: 277  EPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALS 336
            +P  PP +    +A+P+        GLI++ P   A         P PPPPPPP P++  
Sbjct: 1011 DPNKPPELPSTVNAEPL--------GLIQSGPHQAAP-------PPPPPPPPPPAPASEP 1055

Query: 337  TSSLRASM-TSTPP----------------PPVPPPPPPPATALQAPA---VPPPPAPLQ 376
               L + +  ST P                PP   P    A   +  A       PA ++
Sbjct: 1056 KGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIR 1115

Query: 377  IAPGVLHPAPPPIAPPLVQP--SPPVARAAPVCETVPVHPLPQG-EVQGLPPPP-----P 428
            + P  L        P LV    S P        +  P +P P G   +G  P       P
Sbjct: 1116 LNPRRL--------PDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGP 1167

Query: 429  PPPLPPPGIRPSSPVTVTALAHPPSGLHPT 458
            P P   P IR   P+ V   A P S   PT
Sbjct: 1168 PRPRGRPRIR---PLEVPTTAGPASASTPT 1194



 Score = 36.2 bits (82), Expect = 0.082
 Identities = 27/76 (35%), Positives = 35/76 (46%), Gaps = 7/76 (9%)

Query: 424  PPPPPPPPLPPPGIRPSSPVTVTALAHPPS----GLHPTPSTAPGPHVPLMPPSPPSQVI 479
            PP   PP +P  G++P  P T  A+ HPP     GL      A    + L  PSP  ++ 
Sbjct: 1309 PPKSVPPSVPARGLQPQPPAT-PAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRL- 1366

Query: 480  PASEPKRHPSTLPVIS 495
               E KR+  TLP  S
Sbjct: 1367 -DEELKRNLETLPSFS 1381



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 32/120 (26%), Positives = 44/120 (36%), Gaps = 5/120 (4%)

Query: 371  PPAPLQIAPGVLHP--APPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPP 428
            PP P++ +    +P  A    APP   P+PP     P  +T    P  Q     +P PP 
Sbjct: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPE-KTTSEKPPEQTPETAMPEPPA 1728

Query: 429  P--PPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKR 486
            P  P L  P  +      VT    P  G   T      P   L    P +  +P + P +
Sbjct: 1729 PEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTK 1788



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 27/90 (30%), Positives = 36/90 (40%), Gaps = 20/90 (22%)

Query: 270  RVLVRPHEPPPPPPMHGAGDAK-PIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPP 328
            RV  R     PP P+  +G AK P+     SA G     P++PA            PPP 
Sbjct: 1660 RVCARKPWHRPPVPVRRSGQAKNPV-----SAGGSSAPPPKAPA------------PPPK 1702

Query: 329  PPLPSALSTSSL--RASMTSTPPPPVPPPP 356
            P  P   ++     +   T+ P PP P  P
Sbjct: 1703 PETPEKTTSEKPPEQTPETAMPEPPAPEKP 1732



 Score = 30.8 bits (68), Expect = 3.4
 Identities = 27/89 (30%), Positives = 37/89 (41%), Gaps = 11/89 (12%)

Query: 435  PGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSP--PSQVIPASEPKRHPSTLP 492
            P  RP  PV  +  A  P  +    S+AP P  P  PP P  P +      P++ P T  
Sbjct: 1666 PWHRPPVPVRRSGQAKNP--VSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAM 1723

Query: 493  VISDARSVLLEAIRKGIQLRKVEEQREQE 521
                A         K   LR VE+++E+E
Sbjct: 1724 PEPPAP-------EKPSLLRPVEKEKEKE 1745


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.133    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,544,590
Number of Sequences: 37866
Number of extensions: 2884993
Number of successful extensions: 106177
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1501
Number of HSP's successfully gapped in prelim test: 2077
Number of HSP's that attempted gapping in prelim test: 20013
Number of HSP's gapped (non-prelim): 28690
length of query: 559
length of database: 18,247,518
effective HSP length: 107
effective length of query: 452
effective length of database: 14,195,856
effective search space: 6416526912
effective search space used: 6416526912
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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