Guide to the Human Genome
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Name: GCH1 Sequence: fasta or formatted (213aa) NCBI GI: 66932972
Description:

GTP cyclohydrolase 1 isoform 3

Referenced in:

Pteridines and Molybdopterin

Other entries for this name:
alt prot [250aa] GTP cyclohydrolase 1 isoform 1
alt prot [250aa] GTP cyclohydrolase 1 isoform 1
alt prot [233aa] GTP cyclohydrolase 1 isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.9         21           3
 C cysteine            0.9          2           1
 D aspartate           4.7         10           1
 E glutamate           8.9         19           2
 F phenylalanine       2.8          6           2
 G glycine             6.6         14           1
 H histidine           1.9          4           2
 I isoleucine          4.7         10           1
 K lysine              5.6         12           1
 L leucine             7.5         16           2
 M methionine          2.3          5           1
 N asparagine          3.3          7           1
 P proline             9.9         21           2
 Q glutamine           4.2          9           1
 R arginine            7.5         16           2
 S serine              6.6         14           2
 T threonine           2.8          6           1
 V valine              7.0         15           3
 W tryptophan          0.9          2           1
 Y tyrosine            1.9          4           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   GTP cyclohydrolase 1 isoform 3 
GCH1                  0.983   GTP cyclohydrolase 1 isoform 2 
GCH1                  0.980   GTP cyclohydrolase 1 isoform 1 
GCH1                  0.980   GTP cyclohydrolase 1 isoform 1 
PPRC1                 0.042   peroxisome proliferator-activated receptor gamma, co...
RECQL5                0.039   RecQ protein-like 5 isoform 1 
USP51                 0.034   ubiquitin specific protease 51 
SETD1A                0.032   SET domain containing 1A 
LOC100132234          0.030   PREDICTED: hypothetical protein LOC100132234 
LOC100132234          0.027   PREDICTED: hypothetical protein LOC100132234 
LOC100132234          0.027   PREDICTED: hypothetical protein LOC100132234 
LOC100127891          0.025   PREDICTED: similar to hCG2042508 
LOC100127891          0.025   PREDICTED: similar to hCG2042508 
LOC100127891          0.025   PREDICTED: similar to hCG2042508 
JMY                   0.025   junction-mediating and regulatory protein 
LOC100128334          0.025   PREDICTED: similar to hCG1770601 
LOC100128334          0.025   PREDICTED: similar to hCG1770601 
LOC100128334          0.025   PREDICTED: similar to hCG1770601 
LOC100128334          0.025   PREDICTED: similar to hCG1770601 
NACA                  0.025   nascent polypeptide-associated complex alpha subuni...
LOC100131102          0.022   PREDICTED: hypothetical protein 
TAF4                  0.022   TBP-associated factor 4 
ZSCAN10               0.022   zinc finger and SCAN domain containing 10 
SORCS3                0.020   VPS10 domain receptor protein SORCS 3 
LOC100128074          0.020   PREDICTED: hypothetical protein 
ANKRD33B              0.020   PREDICTED: ankyrin repeat domain 33B 
UTF1                  0.020   undifferentiated embryonic cell transcription factor...
MYBPC2                0.020   myosin binding protein C, fast type 
PRB2                  0.020   proline-rich protein BstNI subfamily 2 
FNBP4                 0.020   formin binding protein 4 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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