Search of human proteins with 63252893

Search of human proteins with 63252893

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|63252893 prolyl 4-hydroxylase, alpha II subunit isoform 2
precursor [Homo sapiens]
         (533 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|217272861 prolyl 4-hydroxylase, alpha II subunit isoform 2 pr...  1083   0.0  
gi|63252893 prolyl 4-hydroxylase, alpha II subunit isoform 2 pre...  1083   0.0  
gi|63252891 prolyl 4-hydroxylase, alpha II subunit isoform 2 pre...  1083   0.0  
gi|217272863 prolyl 4-hydroxylase, alpha II subunit isoform 1 pr...  1055   0.0  
gi|4758868 prolyl 4-hydroxylase, alpha II subunit isoform 1 prec...  1055   0.0  
gi|63252886 prolyl 4-hydroxylase, alpha I subunit isoform 1 prec...   691   0.0  
gi|217272849 prolyl 4-hydroxylase, alpha I subunit isoform 2 pre...   681   0.0  
gi|63252888 prolyl 4-hydroxylase, alpha I subunit isoform 2 prec...   681   0.0  
gi|217272851 prolyl 4-hydroxylase, alpha I subunit isoform 3 pre...   643   0.0  
gi|33589818 prolyl 4-hydroxylase, alpha III subunit precursor [H...   327   2e-89
gi|29570771 hypoxia-inducible factor prolyl 4-hydroxylase isofor...    70   6e-12
gi|64085083 hypoxia-inducible factor prolyl 4-hydroxylase isofor...    53   8e-07
gi|197313662 leprecan-like 1 isoform b [Homo sapiens]                  36   0.077
gi|27764882 leprecan-like 1 isoform a [Homo sapiens]                   36   0.077
gi|5454038 synaptonemal complex protein SC65 [Homo sapiens]            34   0.38 
gi|169167211 PREDICTED: FRAS1 related extracellular matrix 3 [Ho...    33   0.85 
gi|169166904 PREDICTED: FRAS1 related extracellular matrix 3 [Ho...    33   0.85 
gi|169166334 PREDICTED: FRAS1 related extracellular matrix 3 [Ho...    33   0.85 
gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo sap...    32   1.9  
gi|56676397 ankyrin repeat domain 11 [Homo sapiens]                    30   4.2  
gi|29788755 SET binding factor 2 [Homo sapiens]                        30   4.2  
gi|223029476 NEL-like protein 2 isoform d [Homo sapiens]               30   5.5  
gi|223029474 NEL-like protein 2 isoform c [Homo sapiens]               30   5.5  
gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens]     30   5.5  
gi|223029470 NEL-like protein 2 isoform a [Homo sapiens]               30   5.5  
gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens]       30   5.5  
gi|163659918 sacsin [Homo sapiens]                                     30   7.2  
gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens]          30   7.2  
gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens]          30   7.2  
gi|4507509 tissue inhibitor of metalloproteinase 1 precursor [Ho...    29   9.4  

>gi|217272861 prolyl 4-hydroxylase, alpha II subunit isoform 2
           precursor [Homo sapiens]
          Length = 533

 Score = 1083 bits (2802), Expect = 0.0
 Identities = 533/533 (100%), Positives = 533/533 (100%)

Query: 1   MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS 60
           MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS
Sbjct: 1   MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS 60

Query: 61  WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR 120
           WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR
Sbjct: 61  WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR 120

Query: 121 QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG 180
           QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG
Sbjct: 121 QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG 180

Query: 181 DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH 240
           DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH
Sbjct: 181 DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH 240

Query: 241 ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK 300
           ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK
Sbjct: 241 ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK 300

Query: 301 LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK 360
           LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK
Sbjct: 301 LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK 360

Query: 361 LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN 420
           LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN
Sbjct: 361 LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN 420

Query: 421 YGVGGQYEPHFDFSRRPFDSGLKTEGNRLATFLNYMSDVEAGGATVFPDLGAAIWPKKGT 480
           YGVGGQYEPHFDFSRRPFDSGLKTEGNRLATFLNYMSDVEAGGATVFPDLGAAIWPKKGT
Sbjct: 421 YGVGGQYEPHFDFSRRPFDSGLKTEGNRLATFLNYMSDVEAGGATVFPDLGAAIWPKKGT 480

Query: 481 AVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 533
           AVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD
Sbjct: 481 AVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 533


>gi|63252893 prolyl 4-hydroxylase, alpha II subunit isoform 2
           precursor [Homo sapiens]
          Length = 533

 Score = 1083 bits (2802), Expect = 0.0
 Identities = 533/533 (100%), Positives = 533/533 (100%)

Query: 1   MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS 60
           MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS
Sbjct: 1   MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS 60

Query: 61  WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR 120
           WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR
Sbjct: 61  WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR 120

Query: 121 QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG 180
           QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG
Sbjct: 121 QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG 180

Query: 181 DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH 240
           DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH
Sbjct: 181 DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH 240

Query: 241 ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK 300
           ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK
Sbjct: 241 ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK 300

Query: 301 LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK 360
           LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK
Sbjct: 301 LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK 360

Query: 361 LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN 420
           LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN
Sbjct: 361 LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN 420

Query: 421 YGVGGQYEPHFDFSRRPFDSGLKTEGNRLATFLNYMSDVEAGGATVFPDLGAAIWPKKGT 480
           YGVGGQYEPHFDFSRRPFDSGLKTEGNRLATFLNYMSDVEAGGATVFPDLGAAIWPKKGT
Sbjct: 421 YGVGGQYEPHFDFSRRPFDSGLKTEGNRLATFLNYMSDVEAGGATVFPDLGAAIWPKKGT 480

Query: 481 AVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 533
           AVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD
Sbjct: 481 AVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 533


>gi|63252891 prolyl 4-hydroxylase, alpha II subunit isoform 2
           precursor [Homo sapiens]
          Length = 533

 Score = 1083 bits (2802), Expect = 0.0
 Identities = 533/533 (100%), Positives = 533/533 (100%)

Query: 1   MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS 60
           MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS
Sbjct: 1   MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS 60

Query: 61  WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR 120
           WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR
Sbjct: 61  WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR 120

Query: 121 QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG 180
           QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG
Sbjct: 121 QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG 180

Query: 181 DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH 240
           DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH
Sbjct: 181 DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH 240

Query: 241 ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK 300
           ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK
Sbjct: 241 ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK 300

Query: 301 LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK 360
           LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK
Sbjct: 301 LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK 360

Query: 361 LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN 420
           LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN
Sbjct: 361 LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN 420

Query: 421 YGVGGQYEPHFDFSRRPFDSGLKTEGNRLATFLNYMSDVEAGGATVFPDLGAAIWPKKGT 480
           YGVGGQYEPHFDFSRRPFDSGLKTEGNRLATFLNYMSDVEAGGATVFPDLGAAIWPKKGT
Sbjct: 421 YGVGGQYEPHFDFSRRPFDSGLKTEGNRLATFLNYMSDVEAGGATVFPDLGAAIWPKKGT 480

Query: 481 AVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 533
           AVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD
Sbjct: 481 AVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 533


>gi|217272863 prolyl 4-hydroxylase, alpha II subunit isoform 1
           precursor [Homo sapiens]
          Length = 535

 Score = 1055 bits (2727), Expect = 0.0
 Identities = 523/535 (97%), Positives = 524/535 (97%), Gaps = 2/535 (0%)

Query: 1   MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS 60
           MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS
Sbjct: 1   MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS 60

Query: 61  WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR 120
           WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR
Sbjct: 61  WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR 120

Query: 121 QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG 180
           QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG
Sbjct: 121 QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG 180

Query: 181 DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH 240
           DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH
Sbjct: 181 DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH 240

Query: 241 ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK 300
           ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK
Sbjct: 241 ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK 300

Query: 301 LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK 360
           LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK
Sbjct: 301 LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK 360

Query: 361 LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN 420
           LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN
Sbjct: 361 LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN 420

Query: 421 YGVGGQYEPHFDFSRRPFDSGLK--TEGNRLATFLNYMSDVEAGGATVFPDLGAAIWPKK 478
           YGVGGQYEPHFDFSR       K    GNR+ATFLNYMSDVEAGGATVFPDLGAAIWPKK
Sbjct: 421 YGVGGQYEPHFDFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKK 480

Query: 479 GTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 533
           GTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD
Sbjct: 481 GTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 535


>gi|4758868 prolyl 4-hydroxylase, alpha II subunit isoform 1
           precursor [Homo sapiens]
          Length = 535

 Score = 1055 bits (2727), Expect = 0.0
 Identities = 523/535 (97%), Positives = 524/535 (97%), Gaps = 2/535 (0%)

Query: 1   MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS 60
           MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS
Sbjct: 1   MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS 60

Query: 61  WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR 120
           WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR
Sbjct: 61  WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR 120

Query: 121 QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG 180
           QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG
Sbjct: 121 QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG 180

Query: 181 DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH 240
           DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH
Sbjct: 181 DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH 240

Query: 241 ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK 300
           ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK
Sbjct: 241 ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK 300

Query: 301 LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK 360
           LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK
Sbjct: 301 LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK 360

Query: 361 LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN 420
           LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN
Sbjct: 361 LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN 420

Query: 421 YGVGGQYEPHFDFSRRPFDSGLK--TEGNRLATFLNYMSDVEAGGATVFPDLGAAIWPKK 478
           YGVGGQYEPHFDFSR       K    GNR+ATFLNYMSDVEAGGATVFPDLGAAIWPKK
Sbjct: 421 YGVGGQYEPHFDFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKK 480

Query: 479 GTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 533
           GTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD
Sbjct: 481 GTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 535


>gi|63252886 prolyl 4-hydroxylase, alpha I subunit isoform 1
           precursor [Homo sapiens]
          Length = 534

 Score =  691 bits (1783), Expect = 0.0
 Identities = 332/537 (61%), Positives = 419/537 (78%), Gaps = 16/537 (2%)

Query: 10  MAWF----GVL---SCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWA 62
           M W+    G+L   S     FFTSIG MTDLI+ EK+LV SLK+YI  EE KL +IK WA
Sbjct: 1   MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWA 60

Query: 63  NKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQRQF 122
            K++ LTS +  D EG++ HPVNA+KL+KRLNT+W  LE+LVL+D + GFI+NL++QRQ+
Sbjct: 61  EKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQY 120

Query: 123 FPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDY 182
           FP DED++GAAKAL+RLQDTY LD  TIS+G LPG K+++ L+ +DCF +G+ AY E DY
Sbjct: 121 FPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADY 180

Query: 183 YHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSHER 242
           YHT LWMEQ L+QLD GE +T  K  VLDYLSYAV+Q GDL +AL LT++LL LDP H+R
Sbjct: 181 YHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR 240

Query: 243 AGGNLRYFEQLLEEERE--KTLTNQTEAELATP--EGIYERPVDYLPERDVYESLCRGEG 298
           A GNL+YFE ++ +E++  K+ ++    +  TP  +G+    VDYLPER  YE LCRGEG
Sbjct: 241 ANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGV---AVDYLPERQKYEMLCRGEG 297

Query: 299 VKLTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAK 358
           +K+TPRRQK+LFCRYH GNR P+ ++AP K+EDEWD P I+R++D++SD EIE +K++AK
Sbjct: 298 IKMTPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAK 357

Query: 359 PKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQV 418
           P+L+RATV DP+TG LT A YRVSKS+WL   ++PVV+R+N R+Q +TGL V TAE LQV
Sbjct: 358 PRLSRATVHDPETGKLTTAQYRVSKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQV 417

Query: 419 ANYGVGGQYEPHFDFSRRPFDSGLKT--EGNRLATFLNYMSDVEAGGATVFPDLGAAIWP 476
           ANYGVGGQYEPHFDF+R+      K    GNR+AT+L YMSDV AGGATVFP++GA++WP
Sbjct: 418 ANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWP 477

Query: 477 KKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 533
           KKGTAVFWYNL  SGEGDY TRHAACPVLVG KWVSNKW HERGQEF RPC  +E++
Sbjct: 478 KKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE 534


>gi|217272849 prolyl 4-hydroxylase, alpha I subunit isoform 2
           precursor [Homo sapiens]
          Length = 534

 Score =  681 bits (1757), Expect = 0.0
 Identities = 327/537 (60%), Positives = 415/537 (77%), Gaps = 16/537 (2%)

Query: 10  MAWF----GVL---SCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWA 62
           M W+    G+L   S     FFTSIG MTDLI+ EK+LV SLK+YI  EE KL +IK WA
Sbjct: 1   MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWA 60

Query: 63  NKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQRQF 122
            K++ LTS +  D EG++ HPVNA+KL+KRLNT+W  LE+LVL+D + GFI+NL++QRQ+
Sbjct: 61  EKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQY 120

Query: 123 FPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDY 182
           FP DED++GAAKAL+RLQDTY LD  TIS+G LPG K+++ L+ +DCF +G+ AY E DY
Sbjct: 121 FPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADY 180

Query: 183 YHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSHER 242
           YHT LWMEQ L+QLD GE +T  K  VLDYLSYAV+Q GDL +AL LT++LL LDP H+R
Sbjct: 181 YHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR 240

Query: 243 AGGNLRYFEQLLEEERE--KTLTNQTEAELATP--EGIYERPVDYLPERDVYESLCRGEG 298
           A GNL+YFE ++ +E++  K+ ++    +  TP  +G+    VDYLPER  YE LCRGEG
Sbjct: 241 ANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGV---AVDYLPERQKYEMLCRGEG 297

Query: 299 VKLTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAK 358
           +K+TPRRQK+LFCRYH GNR P+ ++AP K+EDEWD P I+R++D++SD EIE +K++AK
Sbjct: 298 IKMTPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAK 357

Query: 359 PKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQV 418
           P+L RAT+ +P TG L    YR+SKS+WL   ++PVV+R+N R+Q +TGL V TAE LQV
Sbjct: 358 PRLRRATISNPITGDLETVHYRISKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQV 417

Query: 419 ANYGVGGQYEPHFDFSRRPFDSGLKT--EGNRLATFLNYMSDVEAGGATVFPDLGAAIWP 476
           ANYGVGGQYEPHFDF+R+      K    GNR+AT+L YMSDV AGGATVFP++GA++WP
Sbjct: 418 ANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWP 477

Query: 477 KKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 533
           KKGTAVFWYNL  SGEGDY TRHAACPVLVG KWVSNKW HERGQEF RPC  +E++
Sbjct: 478 KKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE 534


>gi|63252888 prolyl 4-hydroxylase, alpha I subunit isoform 2
           precursor [Homo sapiens]
          Length = 534

 Score =  681 bits (1757), Expect = 0.0
 Identities = 327/537 (60%), Positives = 415/537 (77%), Gaps = 16/537 (2%)

Query: 10  MAWF----GVL---SCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWA 62
           M W+    G+L   S     FFTSIG MTDLI+ EK+LV SLK+YI  EE KL +IK WA
Sbjct: 1   MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWA 60

Query: 63  NKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQRQF 122
            K++ LTS +  D EG++ HPVNA+KL+KRLNT+W  LE+LVL+D + GFI+NL++QRQ+
Sbjct: 61  EKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQY 120

Query: 123 FPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDY 182
           FP DED++GAAKAL+RLQDTY LD  TIS+G LPG K+++ L+ +DCF +G+ AY E DY
Sbjct: 121 FPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADY 180

Query: 183 YHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSHER 242
           YHT LWMEQ L+QLD GE +T  K  VLDYLSYAV+Q GDL +AL LT++LL LDP H+R
Sbjct: 181 YHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR 240

Query: 243 AGGNLRYFEQLLEEERE--KTLTNQTEAELATP--EGIYERPVDYLPERDVYESLCRGEG 298
           A GNL+YFE ++ +E++  K+ ++    +  TP  +G+    VDYLPER  YE LCRGEG
Sbjct: 241 ANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGV---AVDYLPERQKYEMLCRGEG 297

Query: 299 VKLTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAK 358
           +K+TPRRQK+LFCRYH GNR P+ ++AP K+EDEWD P I+R++D++SD EIE +K++AK
Sbjct: 298 IKMTPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAK 357

Query: 359 PKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQV 418
           P+L RAT+ +P TG L    YR+SKS+WL   ++PVV+R+N R+Q +TGL V TAE LQV
Sbjct: 358 PRLRRATISNPITGDLETVHYRISKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQV 417

Query: 419 ANYGVGGQYEPHFDFSRRPFDSGLKT--EGNRLATFLNYMSDVEAGGATVFPDLGAAIWP 476
           ANYGVGGQYEPHFDF+R+      K    GNR+AT+L YMSDV AGGATVFP++GA++WP
Sbjct: 418 ANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWP 477

Query: 477 KKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 533
           KKGTAVFWYNL  SGEGDY TRHAACPVLVG KWVSNKW HERGQEF RPC  +E++
Sbjct: 478 KKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE 534


>gi|217272851 prolyl 4-hydroxylase, alpha I subunit isoform 3
           precursor [Homo sapiens]
          Length = 516

 Score =  643 bits (1658), Expect = 0.0
 Identities = 315/535 (58%), Positives = 400/535 (74%), Gaps = 30/535 (5%)

Query: 10  MAWF----GVL---SCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWA 62
           M W+    G+L   S     FFTSIG MTDLI+ EK+LV SLK+YI  EE KL +IK WA
Sbjct: 1   MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWA 60

Query: 63  NKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQRQF 122
            K++ LTS +  D EG++ HPVNA+KL+KRLNT+W  LE+LVL+D + GFI+NL++QRQ+
Sbjct: 61  EKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQY 120

Query: 123 FPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDY 182
           FP DED++GAAKAL+RLQDTY LD  TIS+G LPG K+++ L+ +DCF +G+ AY E DY
Sbjct: 121 FPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADY 180

Query: 183 YHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSHER 242
           YHT LWMEQ L+QLD GE +T  K  VLDYLSYAV+Q GDL +AL LT++LL LDP H+R
Sbjct: 181 YHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR 240

Query: 243 AGGNLRYFEQLLEEERE--KTLTNQTEAELATP--EGIYERPVDYLPERDVYESLCRGEG 298
           A GNL+YFE ++ +E++  K+ ++    +  TP  +G+    VDYLPER  YE LCRGEG
Sbjct: 241 ANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGV---AVDYLPERQKYEMLCRGEG 297

Query: 299 VKLTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAK 358
           +K+TPRRQK+LFCRYH GNR P+ ++AP K+EDEWD P I+R++D++SD EIE +K++AK
Sbjct: 298 IKMTPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAK 357

Query: 359 PKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQV 418
           P+L+RATV DP+TG LT A YRVSKS+WL   ++PVV+R+N R+Q +TGL V TAE LQ 
Sbjct: 358 PRLSRATVHDPETGKLTTAQYRVSKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQ- 416

Query: 419 ANYGVGGQYEPHFDFSRRPFDSGLKTEGNRLATFLNYMSDVEAGGATVFPDLGAAIWPKK 478
                             P        GNR+AT+L YMSDV AGGATVFP++GA++WPKK
Sbjct: 417 ---------------KDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKK 461

Query: 479 GTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 533
           GTAVFWYNL  SGEGDY TRHAACPVLVG KWVSNKW HERGQEF RPC  +E++
Sbjct: 462 GTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE 516


>gi|33589818 prolyl 4-hydroxylase, alpha III subunit precursor [Homo
           sapiens]
          Length = 544

 Score =  327 bits (837), Expect = 2e-89
 Identities = 197/538 (36%), Positives = 299/538 (55%), Gaps = 38/538 (7%)

Query: 17  SCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWANKMEALTSKSAADA 76
           +  + + F+++  +   +  E+ L+  L+ Y+  EEA+L  +  + +K+ +L   S    
Sbjct: 24  AAARGDTFSALTSVARALAPERRLLGLLRRYLRGEEARLRDLTRFYDKVLSLHEDSTTP- 82

Query: 77  EGYLAHPVNAYKLVKRLNTDWP-ALEDLVLQDSAAGFIANLSVQRQFFPTDEDEIGAAKA 135
              +A+P+ A+ L+KRL +DW   +  L   ++            Q  P  ED  GAA+A
Sbjct: 83  ---VANPLLAFTLIKRLQSDWRNVVHSLEASENIRALKDGYEKVEQDLPAFEDLEGAARA 139

Query: 136 LMRLQDTYRLDPGTISRG-----------ELPGTKYQAMLSVDDCFGMGRSAYNEGDYYH 184
           LMRLQD Y L+   ++RG           +L   K    L+ DDCF +G+ AY+ GDYYH
Sbjct: 140 LMRLQDVYMLNVKGLARGVFQRVTGSAITDLYSPKRLFSLTGDDCFQVGKVAYDMGDYYH 199

Query: 185 TVLWMEQVLKQLDA--GEEATTTKSQV---LDYLSYAVFQLGDLHRALELTRRLLSLDPS 239
            + W+E+ +       GE  T  ++ +   LD+L++A F+ G++  AL L+R  L   P 
Sbjct: 200 AIPWLEEAVSLFRGSYGEWKTEDEASLEDALDHLAFAYFRAGNVSCALSLSREFLLYSPD 259

Query: 240 HERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERP-VDYLPERDVYESLCRGEG 298
           ++R   N+  +E+LL E     +           E + +RP + +L  RD YE LC+  G
Sbjct: 260 NKRMARNVLKYERLLAESPNHVVA----------EAVIQRPNIPHLQTRDTYEGLCQTLG 309

Query: 299 VKLTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAK 358
            + T  +   L+C Y   + A  LL+ P ++E     P+I  Y+D +SD E ++I+E+A+
Sbjct: 310 SQPTLYQIPSLYCSYETNSNA-YLLLQPIRKEVIHLEPYIALYHDFVSDSEAQKIRELAE 368

Query: 359 PKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKT--AELL 416
           P L R+ V   +  +     YR+SKS+WL++  DP +  +N R+  +TGL V+   AE L
Sbjct: 369 PWLQRSVVASGEKQLQV--EYRISKSAWLKDTVDPKLVTLNHRIAALTGLDVRPPYAEYL 426

Query: 417 QVANYGVGGQYEPHFDFSRRPFDSGLKTE-GNRLATFLNYMSDVEAGGATVFPDLGAAIW 475
           QV NYG+GG YEPHFD +  P     + + GNR+ATF+ Y+S VEAGGAT F     ++ 
Sbjct: 427 QVVNYGIGGHYEPHFDHATSPSSPLYRMKSGNRVATFMIYLSSVEAGGATAFIYANLSVP 486

Query: 476 PKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 533
             +  A+FW+NL RSGEGD  T HA CPVLVG KWV+NKW HE GQEF RPC S+  D
Sbjct: 487 VVRNAALFWWNLHRSGEGDSDTLHAGCPVLVGDKWVANKWIHEYGQEFRRPCSSSPED 544


>gi|29570771 hypoxia-inducible factor prolyl 4-hydroxylase isoform a
           [Homo sapiens]
          Length = 502

 Score = 69.7 bits (169), Expect = 6e-12
 Identities = 56/187 (29%), Positives = 78/187 (41%), Gaps = 49/187 (26%)

Query: 380 RVSKSSWLEEDDDP--VVARVNRRMQHITGLTVKTAEL---LQVANYGVGGQYEPHFDFS 434
           R S  +WL + +    ++  + +R+  +T L+ +  EL   LQV  YG GG Y  H D  
Sbjct: 273 RNSHHTWLYQGEGAHHIMRAIRQRVLRLTRLSPEIVELSEPLQVVRYGEGGHYHAHVDSG 332

Query: 435 R---RPFDSGLKTEGN---------RLATFLNYMSDVEAGGATVFP-------------- 468
                   S  K   N         R  T L Y+++V  GG TVFP              
Sbjct: 333 PVYPETICSHTKLVANESVPFETSCRYMTVLFYLNNVTGGGETVFPVADNRTYDEMSLIQ 392

Query: 469 ------------DLG-AAIWPKKGTAVFWYNLLRSGEG-----DYRTRHAACPVLVGCKW 510
                       D G   + P++GTAVFWYN L  G+G     D  + H  C V  G KW
Sbjct: 393 DDVDLRDTRRHCDKGNLRVKPQQGTAVFWYNYLPDGQGWVGDVDDYSLHGGCLVTRGTKW 452

Query: 511 VSNKWFH 517
           ++N W +
Sbjct: 453 IANNWIN 459


>gi|64085083 hypoxia-inducible factor prolyl 4-hydroxylase isoform c
           [Homo sapiens]
          Length = 563

 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 33/99 (33%), Positives = 44/99 (44%), Gaps = 32/99 (32%)

Query: 451 TFLNYMSDVEAGGATVFP--------------------------DLG-AAIWPKKGTAVF 483
           T L Y+++V  GG TVFP                          D G   + P++GTAVF
Sbjct: 422 TVLFYLNNVTGGGETVFPVADNRTYDEMSLIQDDVDLRDTRRHCDKGNLRVKPQQGTAVF 481

Query: 484 WYNLLRSGEG-----DYRTRHAACPVLVGCKWVSNKWFH 517
           WYN L  G+G     D  + H  C V  G KW++N W +
Sbjct: 482 WYNYLPDGQGWVGDVDDYSLHGGCLVTRGTKWIANNWIN 520



 Score = 33.1 bits (74), Expect = 0.65
 Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 5/58 (8%)

Query: 380 RVSKSSWLEEDDDP--VVARVNRRMQHITGLTVKTAEL---LQVANYGVGGQYEPHFD 432
           R S  +WL + +    ++  + +R+  +T L+ +  EL   LQV  YG GG Y  H D
Sbjct: 273 RNSHHTWLYQGEGAHHIMRAIRQRVLRLTRLSPEIVELSEPLQVVRYGEGGHYHAHVD 330


>gi|197313662 leprecan-like 1 isoform b [Homo sapiens]
          Length = 527

 Score = 36.2 bits (82), Expect = 0.077
 Identities = 16/46 (34%), Positives = 27/46 (58%)

Query: 211 DYLSYAVFQLGDLHRALELTRRLLSLDPSHERAGGNLRYFEQLLEE 256
           DYL +A +++G+  +ALE  +  L   P  E    N+ Y+E LL++
Sbjct: 129 DYLQFAYYRVGEYVKALECAKAYLLCHPDDEDVLDNVDYYESLLDD 174


>gi|27764882 leprecan-like 1 isoform a [Homo sapiens]
          Length = 708

 Score = 36.2 bits (82), Expect = 0.077
 Identities = 16/46 (34%), Positives = 27/46 (58%)

Query: 211 DYLSYAVFQLGDLHRALELTRRLLSLDPSHERAGGNLRYFEQLLEE 256
           DYL +A +++G+  +ALE  +  L   P  E    N+ Y+E LL++
Sbjct: 310 DYLQFAYYRVGEYVKALECAKAYLLCHPDDEDVLDNVDYYESLLDD 355


>gi|5454038 synaptonemal complex protein SC65 [Homo sapiens]
          Length = 437

 Score = 33.9 bits (76), Expect = 0.38
 Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 4/70 (5%)

Query: 212 YLSYAVFQLGDLHRALELTRRLLSLDPSHERAGGNLRYFEQLLEEEREKTLTNQTEAELA 271
           YL YA+F+   L +A+      L  +P HE     L Y++ +L+   E    + T+ E  
Sbjct: 147 YLHYALFKANRLEKAVAAAYTFLQRNPKHELTAKYLNYYQGMLDVADE----SLTDLEAQ 202

Query: 272 TPEGIYERPV 281
             E ++ R V
Sbjct: 203 PYEAVFLRAV 212


>gi|169167211 PREDICTED: FRAS1 related extracellular matrix 3 [Homo
           sapiens]
          Length = 2139

 Score = 32.7 bits (73), Expect = 0.85
 Identities = 40/166 (24%), Positives = 69/166 (41%), Gaps = 33/166 (19%)

Query: 237 DPSHERAGGNLR---YFEQLLEEEREKTLTNQTEA-ELATPEGIYERPVDYLPERDVYES 292
           +P  E A G+     Y   LL ++ E  L+ + E       EG+YE+ V    +RD+ E 
Sbjct: 594 EPQWELAPGSSHSGHYLGDLLLQQAELPLSTEDEDWHYMEKEGLYEKVVTEWLQRDIMEG 653

Query: 293 LCRGEGVKLTPRRQKRLFCRYHHGNRAPQLLIA--PFKEEDEWDSPHIVRYYDVMSDEEI 350
                          RLF R H G  +PQ ++    F  +D+ D P+       +S + I
Sbjct: 654 ---------------RLFYR-HLGPHSPQSVMVQLAFHVQDDHDPPN-------LSKQHI 690

Query: 351 ERIK----EIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDD 392
             IK    +I  P+L   T  +       +  ++ +   ++++D D
Sbjct: 691 FTIKVQPVDILSPQLYPGTTLEMTVQEYQLTHFQKNFLRYIDQDSD 736


>gi|169166904 PREDICTED: FRAS1 related extracellular matrix 3 [Homo
           sapiens]
          Length = 2139

 Score = 32.7 bits (73), Expect = 0.85
 Identities = 40/166 (24%), Positives = 69/166 (41%), Gaps = 33/166 (19%)

Query: 237 DPSHERAGGNLR---YFEQLLEEEREKTLTNQTEA-ELATPEGIYERPVDYLPERDVYES 292
           +P  E A G+     Y   LL ++ E  L+ + E       EG+YE+ V    +RD+ E 
Sbjct: 594 EPQWELAPGSSHSGHYLGDLLLQQAELPLSTEDEDWHYMEKEGLYEKVVTEWLQRDIMEG 653

Query: 293 LCRGEGVKLTPRRQKRLFCRYHHGNRAPQLLIA--PFKEEDEWDSPHIVRYYDVMSDEEI 350
                          RLF R H G  +PQ ++    F  +D+ D P+       +S + I
Sbjct: 654 ---------------RLFYR-HLGPHSPQSVMVQLAFHVQDDHDPPN-------LSKQHI 690

Query: 351 ERIK----EIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDD 392
             IK    +I  P+L   T  +       +  ++ +   ++++D D
Sbjct: 691 FTIKVQPVDILSPQLYPGTTLEMTVQEYQLTHFQKNFLRYIDQDSD 736


>gi|169166334 PREDICTED: FRAS1 related extracellular matrix 3 [Homo
           sapiens]
          Length = 2139

 Score = 32.7 bits (73), Expect = 0.85
 Identities = 40/166 (24%), Positives = 69/166 (41%), Gaps = 33/166 (19%)

Query: 237 DPSHERAGGNLR---YFEQLLEEEREKTLTNQTEA-ELATPEGIYERPVDYLPERDVYES 292
           +P  E A G+     Y   LL ++ E  L+ + E       EG+YE+ V    +RD+ E 
Sbjct: 594 EPQWELAPGSSHSGHYLGDLLLQQAELPLSTEDEDWHYMEKEGLYEKVVTEWLQRDIMEG 653

Query: 293 LCRGEGVKLTPRRQKRLFCRYHHGNRAPQLLIA--PFKEEDEWDSPHIVRYYDVMSDEEI 350
                          RLF R H G  +PQ ++    F  +D+ D P+       +S + I
Sbjct: 654 ---------------RLFYR-HLGPHSPQSVMVQLAFHVQDDHDPPN-------LSKQHI 690

Query: 351 ERIK----EIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDD 392
             IK    +I  P+L   T  +       +  ++ +   ++++D D
Sbjct: 691 FTIKVQPVDILSPQLYPGTTLEMTVQEYQLTHFQKNFLRYIDQDSD 736


>gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo
           sapiens]
          Length = 504

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 23/101 (22%), Positives = 41/101 (40%), Gaps = 10/101 (9%)

Query: 191 QVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSHERAGGNLRYF 250
           + +  L A  +     ++    +S   +QLGD   +L   R  L LD  H+R   + +  
Sbjct: 206 KAISDLKAASKLKNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQV 265

Query: 251 ----------EQLLEEEREKTLTNQTEAELATPEGIYERPV 281
                     E+L+ + R    T++ E+ + T   I E  V
Sbjct: 266 KKLNKLIESAEELIRDGRYTDATSKYESVMKTEPSIAEYTV 306


>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
          Length = 2663

 Score = 30.4 bits (67), Expect = 4.2
 Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 5/48 (10%)

Query: 327 FKEEDEWDSPHIVRYYDVMSDEE----IERIKEIAKPKLARATVRDPK 370
           FK ED WDSP +  Y D+ SD      +E +KE +K +   +  R+ +
Sbjct: 852 FKGEDSWDSP-VTDYRDMKSDSVAKLILETVKEDSKERRRDSRAREKR 898


>gi|29788755 SET binding factor 2 [Homo sapiens]
          Length = 1849

 Score = 30.4 bits (67), Expect = 4.2
 Identities = 34/167 (20%), Positives = 66/167 (39%), Gaps = 26/167 (15%)

Query: 258  REKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVKLTPRRQKRLFCRYHH-- 315
            +EK +T Q + +    EG+      +   +  ++     E V++  ++  +   RY    
Sbjct: 952  KEKKITMQNQLQQNMQEGLQITSASFQLIKVAFDEEVSPEVVEIFKKQLMKF--RYPQSI 1009

Query: 316  --------GNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVR 367
                    G   PQ+++   KE++          +   S   ++  K   K  + R  + 
Sbjct: 1010 FSTFAFAAGQTTPQIILPKQKEKNT--------SFRTFSKTIVKGAKRAGKMTIGRQYLL 1061

Query: 368  DPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAE 414
              KTG  T+   RV++  W E+DD      V+   +  T  T+K +E
Sbjct: 1062 KKKTG--TIVEERVNRPGWNEDDD----VSVSDESELPTSTTLKASE 1102


>gi|223029476 NEL-like protein 2 isoform d [Homo sapiens]
          Length = 839

 Score = 30.0 bits (66), Expect = 5.5
 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 6/71 (8%)

Query: 100 LEDLVLQDSAAGFIANLSVQRQFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTK 159
           ++D+ L     GFIA      +  PT  D  G  + +M LQD        +SR E     
Sbjct: 228 MQDVQLLVMPQGFIAQCPDLNRTCPTCNDFHGLVQKIMELQDILAKTSAKLSRAE----- 282

Query: 160 YQAMLSVDDCF 170
            Q M  +D C+
Sbjct: 283 -QRMNRLDQCY 292


>gi|223029474 NEL-like protein 2 isoform c [Homo sapiens]
          Length = 815

 Score = 30.0 bits (66), Expect = 5.5
 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 6/71 (8%)

Query: 100 LEDLVLQDSAAGFIANLSVQRQFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTK 159
           ++D+ L     GFIA      +  PT  D  G  + +M LQD        +SR E     
Sbjct: 204 MQDVQLLVMPQGFIAQCPDLNRTCPTCNDFHGLVQKIMELQDILAKTSAKLSRAE----- 258

Query: 160 YQAMLSVDDCF 170
            Q M  +D C+
Sbjct: 259 -QRMNRLDQCY 268


>gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens]
          Length = 816

 Score = 30.0 bits (66), Expect = 5.5
 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 6/71 (8%)

Query: 100 LEDLVLQDSAAGFIANLSVQRQFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTK 159
           ++D+ L     GFIA      +  PT  D  G  + +M LQD        +SR E     
Sbjct: 205 MQDVQLLVMPQGFIAQCPDLNRTCPTCNDFHGLVQKIMELQDILAKTSAKLSRAE----- 259

Query: 160 YQAMLSVDDCF 170
            Q M  +D C+
Sbjct: 260 -QRMNRLDQCY 269


>gi|223029470 NEL-like protein 2 isoform a [Homo sapiens]
          Length = 866

 Score = 30.0 bits (66), Expect = 5.5
 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 6/71 (8%)

Query: 100 LEDLVLQDSAAGFIANLSVQRQFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTK 159
           ++D+ L     GFIA      +  PT  D  G  + +M LQD        +SR E     
Sbjct: 255 MQDVQLLVMPQGFIAQCPDLNRTCPTCNDFHGLVQKIMELQDILAKTSAKLSRAE----- 309

Query: 160 YQAMLSVDDCF 170
            Q M  +D C+
Sbjct: 310 -QRMNRLDQCY 319


>gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens]
          Length = 816

 Score = 30.0 bits (66), Expect = 5.5
 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 6/71 (8%)

Query: 100 LEDLVLQDSAAGFIANLSVQRQFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTK 159
           ++D+ L     GFIA      +  PT  D  G  + +M LQD        +SR E     
Sbjct: 205 MQDVQLLVMPQGFIAQCPDLNRTCPTCNDFHGLVQKIMELQDILAKTSAKLSRAE----- 259

Query: 160 YQAMLSVDDCF 170
            Q M  +D C+
Sbjct: 260 -QRMNRLDQCY 269


>gi|163659918 sacsin [Homo sapiens]
          Length = 4579

 Score = 29.6 bits (65), Expect = 7.2
 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 3/69 (4%)

Query: 192 VLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSHERAGGNLRYFE 251
           VLK+LDA  +    K  +   L  AV Q+ +     +L  ++ SL P+H+ A   LR F 
Sbjct: 851 VLKKLDASIQHPLIKKYIHSPLPSAVLQIMEKMPLQKLCNQITSLLPTHKDA---LRKFL 907

Query: 252 QLLEEEREK 260
             L +  EK
Sbjct: 908 ASLTDSSEK 916


>gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens]
          Length = 1044

 Score = 29.6 bits (65), Expect = 7.2
 Identities = 34/164 (20%), Positives = 62/164 (37%), Gaps = 28/164 (17%)

Query: 126  DEDEIGAAKALMRLQDTYRLDPGTISRGE-----------------------LPGTKYQA 162
            +E E  A   + RL+D Y  +   + + E                       L G   Q 
Sbjct: 877  EESEKAAESRIKRLRDKYEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQK 936

Query: 163  MLSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGD 222
              +++D   +     +E      V+  E   +   + EE    K+++    +    +L +
Sbjct: 937  ERALEDAQAVNEQLSSERSNLAQVIRQEFEDRLAASEEETRQAKAELATLQARQQLELEE 996

Query: 223  LHRALE--LTRR---LLSLDPSHERAGGNLRYFEQLLEEEREKT 261
            +HR ++  L R+   + SL   HE A     + E+LLE+ R  T
Sbjct: 997  VHRRVKTALARKEEAVSSLRTQHEAAVKRADHLEELLEQHRRPT 1040


>gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens]
          Length = 1080

 Score = 29.6 bits (65), Expect = 7.2
 Identities = 34/164 (20%), Positives = 62/164 (37%), Gaps = 28/164 (17%)

Query: 126  DEDEIGAAKALMRLQDTYRLDPGTISRGE-----------------------LPGTKYQA 162
            +E E  A   + RL+D Y  +   + + E                       L G   Q 
Sbjct: 913  EESEKAAESRIKRLRDKYEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQK 972

Query: 163  MLSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGD 222
              +++D   +     +E      V+  E   +   + EE    K+++    +    +L +
Sbjct: 973  ERALEDAQAVNEQLSSERSNLAQVIRQEFEDRLAASEEETRQAKAELATLQARQQLELEE 1032

Query: 223  LHRALE--LTRR---LLSLDPSHERAGGNLRYFEQLLEEEREKT 261
            +HR ++  L R+   + SL   HE A     + E+LLE+ R  T
Sbjct: 1033 VHRRVKTALARKEEAVSSLRTQHEAAVKRADHLEELLEQHRRPT 1076


>gi|4507509 tissue inhibitor of metalloproteinase 1 precursor [Homo
           sapiens]
          Length = 207

 Score = 29.3 bits (64), Expect = 9.4
 Identities = 20/51 (39%), Positives = 26/51 (50%), Gaps = 3/51 (5%)

Query: 465 TVFPDLGAAIWPKKGTAVFWYN-LLRSGEGDYRTRHAAC-PVLVG-CKWVS 512
           TVFP L      + GT   W + LL+  E  +++RH AC P   G C W S
Sbjct: 151 TVFPCLSIPCKLQSGTHCLWTDQLLQGSEKGFQSRHLACLPREPGLCTWQS 201


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,136,477
Number of Sequences: 37866
Number of extensions: 880443
Number of successful extensions: 2307
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 2263
Number of HSP's gapped (non-prelim): 40
length of query: 533
length of database: 18,247,518
effective HSP length: 107
effective length of query: 426
effective length of database: 14,195,856
effective search space: 6047434656
effective search space used: 6047434656
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.