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Search of human proteins with 63252870
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|63252870 osteosarcoma amplified 9 isoform 4 precursor [Homo
sapiens]
(652 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|63252870 osteosarcoma amplified 9 isoform 4 precursor [Homo s... 1323 0.0
gi|5803109 osteosarcoma amplified 9 isoform 1 precursor [Homo sa... 1313 0.0
gi|63252868 osteosarcoma amplified 9 isoform 3 precursor [Homo s... 1177 0.0
gi|63252866 osteosarcoma amplified 9 isoform 2 precursor [Homo s... 1167 0.0
gi|188528698 erlectin isoform 3 [Homo sapiens] 96 1e-19
gi|188528696 erlectin isoform 2 [Homo sapiens] 96 1e-19
gi|20070264 erlectin isoform 1 [Homo sapiens] 96 1e-19
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 57 5e-08
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami... 56 9e-08
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 56 9e-08
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 56 9e-08
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 56 1e-07
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 54 5e-07
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 54 5e-07
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 53 1e-06
gi|55956788 nucleolin [Homo sapiens] 52 1e-06
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 52 2e-06
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 52 2e-06
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 51 3e-06
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 51 4e-06
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 51 4e-06
gi|8923771 ELG protein isoform b [Homo sapiens] 50 5e-06
gi|166295179 ELG protein isoform a [Homo sapiens] 50 5e-06
gi|17975763 myelin transcription factor 1 [Homo sapiens] 49 1e-05
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 49 1e-05
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 49 1e-05
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 49 1e-05
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 49 2e-05
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 49 2e-05
gi|148746195 trichohyalin [Homo sapiens] 48 3e-05
>gi|63252870 osteosarcoma amplified 9 isoform 4 precursor [Homo
sapiens]
Length = 652
Score = 1323 bits (3425), Expect = 0.0
Identities = 652/652 (100%), Positives = 652/652 (100%)
Query: 1 MAAETLLSSLLGLLLLGLLLPASLTGGVGSLNLEELSEMRYGIEILPLPVMGGQSQSSDV 60
MAAETLLSSLLGLLLLGLLLPASLTGGVGSLNLEELSEMRYGIEILPLPVMGGQSQSSDV
Sbjct: 1 MAAETLLSSLLGLLLLGLLLPASLTGGVGSLNLEELSEMRYGIEILPLPVMGGQSQSSDV 60
Query: 61 VIVSSKYKQRYECRLPAGAIHFQREREEETPAYQGPGIPELLSPMRDAPCLLKTKDWWTY 120
VIVSSKYKQRYECRLPAGAIHFQREREEETPAYQGPGIPELLSPMRDAPCLLKTKDWWTY
Sbjct: 61 VIVSSKYKQRYECRLPAGAIHFQREREEETPAYQGPGIPELLSPMRDAPCLLKTKDWWTY 120
Query: 121 EFCYGRHIQQYHMEDSEIKGEVLYLGYYQSAFDWDDETAKASKQHRLKRYHSQTYGNGSK 180
EFCYGRHIQQYHMEDSEIKGEVLYLGYYQSAFDWDDETAKASKQHRLKRYHSQTYGNGSK
Sbjct: 121 EFCYGRHIQQYHMEDSEIKGEVLYLGYYQSAFDWDDETAKASKQHRLKRYHSQTYGNGSK 180
Query: 181 CDLNGRPREAEVRFLCDEGAGISGDYIDRVDEPLSCSYVLTIRTPRLCPHPLLRPPPSAA 240
CDLNGRPREAEVRFLCDEGAGISGDYIDRVDEPLSCSYVLTIRTPRLCPHPLLRPPPSAA
Sbjct: 181 CDLNGRPREAEVRFLCDEGAGISGDYIDRVDEPLSCSYVLTIRTPRLCPHPLLRPPPSAA 240
Query: 241 PQAILCHPSLQPEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGAS 300
PQAILCHPSLQPEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGAS
Sbjct: 241 PQAILCHPSLQPEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGAS 300
Query: 301 PTKDDSKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIR 360
PTKDDSKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIR
Sbjct: 301 PTKDDSKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIR 360
Query: 361 SPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDED 420
SPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDED
Sbjct: 361 SPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDED 420
Query: 421 EDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLALTS 480
EDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLALTS
Sbjct: 421 EDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLALTS 480
Query: 481 TLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTEEDPEHRVRVRVTKLRLGGPNQ 540
TLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTEEDPEHRVRVRVTKLRLGGPNQ
Sbjct: 481 TLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTEEDPEHRVRVRVTKLRLGGPNQ 540
Query: 541 DLTVLEMKRENPQLKQIEGLVKELLEREGLTAAGKIEIKIVRPWAEGTEEGARWLTDEDT 600
DLTVLEMKRENPQLKQIEGLVKELLEREGLTAAGKIEIKIVRPWAEGTEEGARWLTDEDT
Sbjct: 541 DLTVLEMKRENPQLKQIEGLVKELLEREGLTAAGKIEIKIVRPWAEGTEEGARWLTDEDT 600
Query: 601 RNLKEIFFNILVPGAEEAQKERQRQKELESNYRRVWGSPGGEGTGDLDEFDF 652
RNLKEIFFNILVPGAEEAQKERQRQKELESNYRRVWGSPGGEGTGDLDEFDF
Sbjct: 601 RNLKEIFFNILVPGAEEAQKERQRQKELESNYRRVWGSPGGEGTGDLDEFDF 652
>gi|5803109 osteosarcoma amplified 9 isoform 1 precursor [Homo
sapiens]
Length = 667
Score = 1313 bits (3399), Expect = 0.0
Identities = 652/667 (97%), Positives = 652/667 (97%), Gaps = 15/667 (2%)
Query: 1 MAAETLLSSLLGLLLLGLLLPASLTGGVGSLNLEELSEMRYGIEILPLPVMGGQSQSSDV 60
MAAETLLSSLLGLLLLGLLLPASLTGGVGSLNLEELSEMRYGIEILPLPVMGGQSQSSDV
Sbjct: 1 MAAETLLSSLLGLLLLGLLLPASLTGGVGSLNLEELSEMRYGIEILPLPVMGGQSQSSDV 60
Query: 61 VIVSSKYKQRYECRLPAGAIHFQREREEETPAYQGPGIPELLSPMRDAPCLLKTKDWWTY 120
VIVSSKYKQRYECRLPAGAIHFQREREEETPAYQGPGIPELLSPMRDAPCLLKTKDWWTY
Sbjct: 61 VIVSSKYKQRYECRLPAGAIHFQREREEETPAYQGPGIPELLSPMRDAPCLLKTKDWWTY 120
Query: 121 EFCYGRHIQQYHMEDSEIKGEVLYLGYYQSAFDWDDETAKASKQHRLKRYHSQTYGNGSK 180
EFCYGRHIQQYHMEDSEIKGEVLYLGYYQSAFDWDDETAKASKQHRLKRYHSQTYGNGSK
Sbjct: 121 EFCYGRHIQQYHMEDSEIKGEVLYLGYYQSAFDWDDETAKASKQHRLKRYHSQTYGNGSK 180
Query: 181 CDLNGRPREAEVRFLCDEGAGISGDYIDRVDEPLSCSYVLTIRTPRLCPHPLLRPPPSAA 240
CDLNGRPREAEVRFLCDEGAGISGDYIDRVDEPLSCSYVLTIRTPRLCPHPLLRPPPSAA
Sbjct: 181 CDLNGRPREAEVRFLCDEGAGISGDYIDRVDEPLSCSYVLTIRTPRLCPHPLLRPPPSAA 240
Query: 241 PQAILCHPSLQPEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGAS 300
PQAILCHPSLQPEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGAS
Sbjct: 241 PQAILCHPSLQPEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGAS 300
Query: 301 PTKDDSKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIR 360
PTKDDSKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIR
Sbjct: 301 PTKDDSKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIR 360
Query: 361 SPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDED 420
SPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDED
Sbjct: 361 SPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDED 420
Query: 421 EDEDEDEDERQLLGEFEKELEGILLPSDRDRLRS---------------ETEKELDPDGL 465
EDEDEDEDERQLLGEFEKELEGILLPSDRDRLRS ETEKELDPDGL
Sbjct: 421 EDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSEVKAGMERELENIIQETEKELDPDGL 480
Query: 466 KKESERDRAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTEEDPEHR 525
KKESERDRAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTEEDPEHR
Sbjct: 481 KKESERDRAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTEEDPEHR 540
Query: 526 VRVRVTKLRLGGPNQDLTVLEMKRENPQLKQIEGLVKELLEREGLTAAGKIEIKIVRPWA 585
VRVRVTKLRLGGPNQDLTVLEMKRENPQLKQIEGLVKELLEREGLTAAGKIEIKIVRPWA
Sbjct: 541 VRVRVTKLRLGGPNQDLTVLEMKRENPQLKQIEGLVKELLEREGLTAAGKIEIKIVRPWA 600
Query: 586 EGTEEGARWLTDEDTRNLKEIFFNILVPGAEEAQKERQRQKELESNYRRVWGSPGGEGTG 645
EGTEEGARWLTDEDTRNLKEIFFNILVPGAEEAQKERQRQKELESNYRRVWGSPGGEGTG
Sbjct: 601 EGTEEGARWLTDEDTRNLKEIFFNILVPGAEEAQKERQRQKELESNYRRVWGSPGGEGTG 660
Query: 646 DLDEFDF 652
DLDEFDF
Sbjct: 661 DLDEFDF 667
>gi|63252868 osteosarcoma amplified 9 isoform 3 precursor [Homo
sapiens]
Length = 597
Score = 1177 bits (3044), Expect = 0.0
Identities = 588/652 (90%), Positives = 594/652 (91%), Gaps = 55/652 (8%)
Query: 1 MAAETLLSSLLGLLLLGLLLPASLTGGVGSLNLEELSEMRYGIEILPLPVMGGQSQSSDV 60
MAAETLLSSLLGLLLLGLLLPASLTGGVGSLNLEELSEMRYGIEILPLPVMGGQSQSSDV
Sbjct: 1 MAAETLLSSLLGLLLLGLLLPASLTGGVGSLNLEELSEMRYGIEILPLPVMGGQSQSSDV 60
Query: 61 VIVSSKYKQRYECRLPAGAIHFQREREEETPAYQGPGIPELLSPMRDAPCLLKTKDWWTY 120
VIVSSKYKQRYECRLPAGAIHFQREREEETPAYQGPGIPELLSPMRDAPCLLKTKDWWTY
Sbjct: 61 VIVSSKYKQRYECRLPAGAIHFQREREEETPAYQGPGIPELLSPMRDAPCLLKTKDWWTY 120
Query: 121 EFCYGRHIQQYHMEDSEIKGEVLYLGYYQSAFDWDDETAKASKQHRLKRYHSQTYGNGSK 180
EFCYGRHIQQYHMEDSEIKGEVLYLGYYQSAFDWDDETAKASKQHRLKRYHSQTYGNGSK
Sbjct: 121 EFCYGRHIQQYHMEDSEIKGEVLYLGYYQSAFDWDDETAKASKQHRLKRYHSQTYGNGSK 180
Query: 181 CDLNGRPREAEVRFLCDEGAGISGDYIDRVDEPLSCSYVLTIRTPRLCPHPLLRPPPSAA 240
CDLNGRPREAEVRFLCDEGAGISGDYIDRVDEPLSCSYVLTIRTPRLCPHPLLRPPPSAA
Sbjct: 181 CDLNGRPREAEVRFLCDEGAGISGDYIDRVDEPLSCSYVLTIRTPRLCPHPLLRPPPSAA 240
Query: 241 PQAILCHPSLQPEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGAS 300
PQAILCHPSLQPEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGAS
Sbjct: 241 PQAILCHPSLQPEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGAS 300
Query: 301 PTKDDSKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIR 360
PTKDDSKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIR
Sbjct: 301 PTKDDSKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIR 360
Query: 361 SPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDED 420
SPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDED
Sbjct: 361 SPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDED 420
Query: 421 EDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLALTS 480
EDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLALTS
Sbjct: 421 EDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLALTS 480
Query: 481 TLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTEEDPEHRVRVRVTKLRLGGPNQ 540
TLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPT ++ +++ +
Sbjct: 481 TLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPT-----GKIEIKIVR-------- 527
Query: 541 DLTVLEMKRENPQLKQIEGLVKELLEREGLTAAGKIEIKIVRPWAEGTEEGARWLTDEDT 600
PWAEGTEEGARWLTDEDT
Sbjct: 528 ------------------------------------------PWAEGTEEGARWLTDEDT 545
Query: 601 RNLKEIFFNILVPGAEEAQKERQRQKELESNYRRVWGSPGGEGTGDLDEFDF 652
RNLKEIFFNILVPGAEEAQKERQRQKELESNYRRVWGSPGGEGTGDLDEFDF
Sbjct: 546 RNLKEIFFNILVPGAEEAQKERQRQKELESNYRRVWGSPGGEGTGDLDEFDF 597
>gi|63252866 osteosarcoma amplified 9 isoform 2 precursor [Homo
sapiens]
Length = 612
Score = 1167 bits (3018), Expect = 0.0
Identities = 588/667 (88%), Positives = 594/667 (89%), Gaps = 70/667 (10%)
Query: 1 MAAETLLSSLLGLLLLGLLLPASLTGGVGSLNLEELSEMRYGIEILPLPVMGGQSQSSDV 60
MAAETLLSSLLGLLLLGLLLPASLTGGVGSLNLEELSEMRYGIEILPLPVMGGQSQSSDV
Sbjct: 1 MAAETLLSSLLGLLLLGLLLPASLTGGVGSLNLEELSEMRYGIEILPLPVMGGQSQSSDV 60
Query: 61 VIVSSKYKQRYECRLPAGAIHFQREREEETPAYQGPGIPELLSPMRDAPCLLKTKDWWTY 120
VIVSSKYKQRYECRLPAGAIHFQREREEETPAYQGPGIPELLSPMRDAPCLLKTKDWWTY
Sbjct: 61 VIVSSKYKQRYECRLPAGAIHFQREREEETPAYQGPGIPELLSPMRDAPCLLKTKDWWTY 120
Query: 121 EFCYGRHIQQYHMEDSEIKGEVLYLGYYQSAFDWDDETAKASKQHRLKRYHSQTYGNGSK 180
EFCYGRHIQQYHMEDSEIKGEVLYLGYYQSAFDWDDETAKASKQHRLKRYHSQTYGNGSK
Sbjct: 121 EFCYGRHIQQYHMEDSEIKGEVLYLGYYQSAFDWDDETAKASKQHRLKRYHSQTYGNGSK 180
Query: 181 CDLNGRPREAEVRFLCDEGAGISGDYIDRVDEPLSCSYVLTIRTPRLCPHPLLRPPPSAA 240
CDLNGRPREAEVRFLCDEGAGISGDYIDRVDEPLSCSYVLTIRTPRLCPHPLLRPPPSAA
Sbjct: 181 CDLNGRPREAEVRFLCDEGAGISGDYIDRVDEPLSCSYVLTIRTPRLCPHPLLRPPPSAA 240
Query: 241 PQAILCHPSLQPEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGAS 300
PQAILCHPSLQPEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGAS
Sbjct: 241 PQAILCHPSLQPEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGAS 300
Query: 301 PTKDDSKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIR 360
PTKDDSKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIR
Sbjct: 301 PTKDDSKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIR 360
Query: 361 SPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDED 420
SPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDED
Sbjct: 361 SPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDED 420
Query: 421 EDEDEDEDERQLLGEFEKELEGILLPSDRDRLRS---------------ETEKELDPDGL 465
EDEDEDEDERQLLGEFEKELEGILLPSDRDRLRS ETEKELDPDGL
Sbjct: 421 EDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSEVKAGMERELENIIQETEKELDPDGL 480
Query: 466 KKESERDRAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTEEDPEHR 525
KKESERDRAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPT +
Sbjct: 481 KKESERDRAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPT-----GK 535
Query: 526 VRVRVTKLRLGGPNQDLTVLEMKRENPQLKQIEGLVKELLEREGLTAAGKIEIKIVRPWA 585
+ +++ + PWA
Sbjct: 536 IEIKIVR--------------------------------------------------PWA 545
Query: 586 EGTEEGARWLTDEDTRNLKEIFFNILVPGAEEAQKERQRQKELESNYRRVWGSPGGEGTG 645
EGTEEGARWLTDEDTRNLKEIFFNILVPGAEEAQKERQRQKELESNYRRVWGSPGGEGTG
Sbjct: 546 EGTEEGARWLTDEDTRNLKEIFFNILVPGAEEAQKERQRQKELESNYRRVWGSPGGEGTG 605
Query: 646 DLDEFDF 652
DLDEFDF
Sbjct: 606 DLDEFDF 612
>gi|188528698 erlectin isoform 3 [Homo sapiens]
Length = 429
Score = 95.9 bits (237), Expect = 1e-19
Identities = 65/204 (31%), Positives = 99/204 (48%), Gaps = 24/204 (11%)
Query: 48 LPVMGGQSQSSDVVIVSSKYKQRYECRLPAGAIHFQREREEETPAYQGPGIPELLSPM-R 106
LP G + + VI+++ +K++Y+C LP EEE Y+GP ELL P+ +
Sbjct: 54 LPTTGVLYKEDNYVIMTTAHKEKYKCILPL----VTSGDEEEEKDYKGPNPRELLEPLFK 109
Query: 107 DAPCLLKTKDWWTYEFCYGRHIQQYHME---DSEIKGEVLYLGYYQS---AFDWDDETAK 160
+ C + + +WTYE C+G+HI+QYH E +I YLG + F+ + E +
Sbjct: 110 QSSCSYRIESYWTYEVCHGKHIRQYHEEKETGQKINIHEYYLGNMLAKNLLFEKEREAEE 169
Query: 161 ASKQH---------RLKRYHSQTYGNGSKCDL-NGRPREAEVRFLCDEGAGISGDYIDRV 210
K + ++ Y+ GNG+ C L RPR + V ++C S I V
Sbjct: 170 KEKSNEIPTKNIEGQMTPYYPVGMGNGTPCSLKQNRPRSSTVMYICHPE---SKHEILSV 226
Query: 211 DEPLSCSYVLTIRTPRLCPHPLLR 234
E +C Y + I TP LC HP R
Sbjct: 227 AEVTTCEYEVVILTPLLCSHPKYR 250
Score = 74.3 bits (181), Expect = 3e-13
Identities = 39/124 (31%), Positives = 60/124 (48%), Gaps = 19/124 (15%)
Query: 117 WWTYEFCYGRHIQQYHMEDSEIKGEVLYLGYYQSAFDWDDETAKASKQHRLKRYH----- 171
WW YEFCYG+H+ QYH + K V+ + Q +E + +K++ + YH
Sbjct: 297 WWKYEFCYGKHVHQYHEDKDSGKTSVVVGTWNQ------EEHIEWAKKNTARAYHLQDDG 350
Query: 172 -------SQTYGNGSKCDLNGRPREAEVRFLCDEGAGISGDYIDRVDEPLSCSYVLTIRT 224
S YGNG CD+ +PR+ V+ C E + + EP SC Y+L + +
Sbjct: 351 TQTVRMVSHFYGNGDICDITDKPRQVTVKLKCKESDSPHAVTVYML-EPHSCQYILGVES 409
Query: 225 PRLC 228
P +C
Sbjct: 410 PVIC 413
>gi|188528696 erlectin isoform 2 [Homo sapiens]
Length = 457
Score = 95.9 bits (237), Expect = 1e-19
Identities = 65/204 (31%), Positives = 99/204 (48%), Gaps = 24/204 (11%)
Query: 48 LPVMGGQSQSSDVVIVSSKYKQRYECRLPAGAIHFQREREEETPAYQGPGIPELLSPM-R 106
LP G + + VI+++ +K++Y+C LP EEE Y+GP ELL P+ +
Sbjct: 54 LPTTGVLYKEDNYVIMTTAHKEKYKCILPL----VTSGDEEEEKDYKGPNPRELLEPLFK 109
Query: 107 DAPCLLKTKDWWTYEFCYGRHIQQYHME---DSEIKGEVLYLGYYQS---AFDWDDETAK 160
+ C + + +WTYE C+G+HI+QYH E +I YLG + F+ + E +
Sbjct: 110 QSSCSYRIESYWTYEVCHGKHIRQYHEEKETGQKINIHEYYLGNMLAKNLLFEKEREAEE 169
Query: 161 ASKQH---------RLKRYHSQTYGNGSKCDL-NGRPREAEVRFLCDEGAGISGDYIDRV 210
K + ++ Y+ GNG+ C L RPR + V ++C S I V
Sbjct: 170 KEKSNEIPTKNIEGQMTPYYPVGMGNGTPCSLKQNRPRSSTVMYICHPE---SKHEILSV 226
Query: 211 DEPLSCSYVLTIRTPRLCPHPLLR 234
E +C Y + I TP LC HP R
Sbjct: 227 AEVTTCEYEVVILTPLLCSHPKYR 250
Score = 57.4 bits (137), Expect = 4e-08
Identities = 33/113 (29%), Positives = 51/113 (45%), Gaps = 23/113 (20%)
Query: 117 WWTYEFCYGRHIQQYHMEDSEIKGEVLYLGYYQSAFDWDDETAKASKQHRLKRYHSQTYG 176
WW YEFCYG+H+ QYH + K V+ + Q +E + +K++ + YH Q G
Sbjct: 351 WWKYEFCYGKHVHQYHEDKDSGKTSVVVGTWNQ------EEHIEWAKKNTARAYHLQDDG 404
Query: 177 NGS-KCDLNGRPREAEVRFLCDEGAGISGDYIDRVDEPLSCSYVLTIRTPRLC 228
+ +C + P V L EP SC Y+L + +P +C
Sbjct: 405 TQTVRCKESDSPHAVTVYML----------------EPHSCQYILGVESPVIC 441
>gi|20070264 erlectin isoform 1 [Homo sapiens]
Length = 483
Score = 95.9 bits (237), Expect = 1e-19
Identities = 65/204 (31%), Positives = 99/204 (48%), Gaps = 24/204 (11%)
Query: 48 LPVMGGQSQSSDVVIVSSKYKQRYECRLPAGAIHFQREREEETPAYQGPGIPELLSPM-R 106
LP G + + VI+++ +K++Y+C LP EEE Y+GP ELL P+ +
Sbjct: 54 LPTTGVLYKEDNYVIMTTAHKEKYKCILPL----VTSGDEEEEKDYKGPNPRELLEPLFK 109
Query: 107 DAPCLLKTKDWWTYEFCYGRHIQQYHME---DSEIKGEVLYLGYYQS---AFDWDDETAK 160
+ C + + +WTYE C+G+HI+QYH E +I YLG + F+ + E +
Sbjct: 110 QSSCSYRIESYWTYEVCHGKHIRQYHEEKETGQKINIHEYYLGNMLAKNLLFEKEREAEE 169
Query: 161 ASKQH---------RLKRYHSQTYGNGSKCDL-NGRPREAEVRFLCDEGAGISGDYIDRV 210
K + ++ Y+ GNG+ C L RPR + V ++C S I V
Sbjct: 170 KEKSNEIPTKNIEGQMTPYYPVGMGNGTPCSLKQNRPRSSTVMYICHPE---SKHEILSV 226
Query: 211 DEPLSCSYVLTIRTPRLCPHPLLR 234
E +C Y + I TP LC HP R
Sbjct: 227 AEVTTCEYEVVILTPLLCSHPKYR 250
Score = 74.3 bits (181), Expect = 3e-13
Identities = 39/124 (31%), Positives = 60/124 (48%), Gaps = 19/124 (15%)
Query: 117 WWTYEFCYGRHIQQYHMEDSEIKGEVLYLGYYQSAFDWDDETAKASKQHRLKRYH----- 171
WW YEFCYG+H+ QYH + K V+ + Q +E + +K++ + YH
Sbjct: 351 WWKYEFCYGKHVHQYHEDKDSGKTSVVVGTWNQ------EEHIEWAKKNTARAYHLQDDG 404
Query: 172 -------SQTYGNGSKCDLNGRPREAEVRFLCDEGAGISGDYIDRVDEPLSCSYVLTIRT 224
S YGNG CD+ +PR+ V+ C E + + EP SC Y+L + +
Sbjct: 405 TQTVRMVSHFYGNGDICDITDKPRQVTVKLKCKESDSPHAVTVYML-EPHSCQYILGVES 463
Query: 225 PRLC 228
P +C
Sbjct: 464 PVIC 467
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 57.0 bits (136), Expect = 5e-08
Identities = 69/249 (27%), Positives = 112/249 (44%), Gaps = 22/249 (8%)
Query: 394 EVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLR 453
E ++E EKER + ER+RE E E E E E E E ER+ E E+E E DRDR R
Sbjct: 299 EKERQEIEKERRERERERERERERREREREREREREREKEKERERERE-----RDRDRDR 353
Query: 454 SETEKELDPDGLKKESERDRAMLALTSTLNKLIKRLEEK-QSPELVKKHKKKRVVPKKPP 512
++ E++ D D +E +RDR +S NK R EK + E ++ +++R ++
Sbjct: 354 TK-ERDRDRD---RERDRDRDR-ERSSDRNKDRSRSREKSRDRERERERERERERERERE 408
Query: 513 PSPQPTEEDPEHRVRVRVTKLRLGGPNQDLTVLEMKRENPQLKQIEGLVKELLEREGLTA 572
+ E R R R + + E ++ +L++ E +E L+ +
Sbjct: 409 REREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRE 468
Query: 573 AGKIEIKIVRPWAEGTEEGARWLTDEDTRNLKEIFFNI--------LVPGAEEAQKERQR 624
K + AE EE R + E + LKE + G+ ++ R R
Sbjct: 469 RKK--TREYEKEAEREEERRREMAKE-AKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDR 525
Query: 625 QKELESNYR 633
+KE+E++ R
Sbjct: 526 EKEMEADER 534
Score = 40.8 bits (94), Expect = 0.004
Identities = 44/149 (29%), Positives = 70/149 (46%), Gaps = 20/149 (13%)
Query: 398 REPEKE-RGDPERQREMEEEED------EDEDEDEDEDE-------RQLLGEFEKELEGI 443
RE EKE + ER+REM +E ED D+D D+ + ++ L + EKE+E
Sbjct: 473 REYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEA- 531
Query: 444 LLPSDRDRLRSETEKELDPDGLKKESERD-RAMLALTSTLNKLIKRLEEKQSPELVKKHK 502
+RDR R + E E L E D A L + ++ + KQ PE ++ +
Sbjct: 532 ---DERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEE 588
Query: 503 KKRVVPKKPPPSPQPTEEDPEHRVRVRVT 531
+K+ +K P EE+PE + ++ T
Sbjct: 589 EKQEKEEK-REEPMEEEEEPEQKPCLKPT 616
Score = 33.5 bits (75), Expect = 0.63
Identities = 18/52 (34%), Positives = 31/52 (59%)
Query: 390 DDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELE 441
D AE+ + E E ER + ++ E E+E+E++ E E++R+ E E+E E
Sbjct: 557 DPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPE 608
Score = 32.7 bits (73), Expect = 1.1
Identities = 52/263 (19%), Positives = 101/263 (38%), Gaps = 34/263 (12%)
Query: 380 KPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKE 439
K +I + +D ++ RE K R + +++EEE+ + E E ++ ++ + E E+E
Sbjct: 261 KEDINAIEMEEDKRDLISREISKFR---DTHKKLEEEKGKKEKERQEIEKERRERERERE 317
Query: 440 LEGILLPSDRDRLRSETEKELDPD-------GLKKESERDRAMLALTSTLNKLIKRLEEK 492
R+R R E E+E + + ++E ERDR + +
Sbjct: 318 ---------RERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRD 368
Query: 493 QSPELVKKHKKKRVVPKKPPPSPQPTEEDPEHRVRVRVTKLRLGGPNQDLTVLEMKRENP 552
+ E K R ++ + E R R R + + E +RE
Sbjct: 369 RDRERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKD 428
Query: 553 QLKQIEGLVKELLEREGLTAAGKIEIKIVRPWAEGTEEGARWLTDEDTRNLKEIFFNILV 612
+ + E ++ ER K+E K+ A E W E + +
Sbjct: 429 KKRDREEDEEDAYERR------KLERKLREKEAAYQERLKNWEIRERKKTREY------- 475
Query: 613 PGAEEAQKERQRQKELESNYRRV 635
+EA++E +R++E+ +R+
Sbjct: 476 --EKEAEREEERRREMAKEAKRL 496
Score = 31.6 bits (70), Expect = 2.4
Identities = 32/121 (26%), Positives = 53/121 (43%), Gaps = 18/121 (14%)
Query: 398 REPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETE 457
R+ EKE ER R+ E+EE E E ++LL E + + ++ R+ E E
Sbjct: 523 RDREKEMEADERDRKREKEELE-------EIRQRLLAEGHPDPD-----AELQRMEQEAE 570
Query: 458 KELDPDGLKKESERDRAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQP 517
+ P +K+E E + K + +EE++ PE +K + P P S P
Sbjct: 571 RRRQPQ-IKQEPESEEEEEEKQEKEEKREEPMEEEEEPE-----QKPCLKPTLRPISSAP 624
Query: 518 T 518
+
Sbjct: 625 S 625
Score = 30.4 bits (67), Expect = 5.3
Identities = 12/33 (36%), Positives = 22/33 (66%)
Query: 397 QREPEKERGDPERQREMEEEEDEDEDEDEDEDE 429
++EPE E + E+Q + E+ E+ E+E+E E +
Sbjct: 578 KQEPESEEEEEEKQEKEEKREEPMEEEEEPEQK 610
>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member E isoform 1 [Homo sapiens]
Length = 268
Score = 56.2 bits (134), Expect = 9e-08
Identities = 37/90 (41%), Positives = 50/90 (55%), Gaps = 8/90 (8%)
Query: 385 QEQPVDDAAEVPQREPEKERGDPER-QREMEEEEDEDEDEDEDEDER-QLLGEFEKELEG 442
+E+ +D E + E E E G PE + E EEEE+EDEDEDEDEDE LGE E+E+
Sbjct: 159 EEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGL 218
Query: 443 ILLPSDRDRLRSETEKELDPDGLKKESERD 472
L ++ E + E D D +E E +
Sbjct: 219 SYL------MKEEIQDEEDDDDYVEEGEEE 242
Score = 37.0 bits (84), Expect = 0.057
Identities = 25/120 (20%), Positives = 48/120 (40%), Gaps = 10/120 (8%)
Query: 316 NEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIRSPADLIRFIEELKGG 375
++ +++AP EE E+ D E + P + + + D +E
Sbjct: 149 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 208
Query: 376 TKKGKPNIG----------QEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDE 425
+G+ +G E+ DD E + E E+E G ++ + ED+ E+ED+
Sbjct: 209 LGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 268
Score = 34.3 bits (77), Expect = 0.37
Identities = 26/72 (36%), Positives = 35/72 (48%), Gaps = 11/72 (15%)
Query: 412 EMEEEEDEDEDEDEDEDERQLLG--------EFEKELEGILLPSDRDRLRSET---EKEL 460
+ EEE+DED DED++E+E G E E+E E D D SE E+E+
Sbjct: 157 DSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEV 216
Query: 461 DPDGLKKESERD 472
L KE +D
Sbjct: 217 GLSYLMKEEIQD 228
Score = 31.2 bits (69), Expect = 3.1
Identities = 17/60 (28%), Positives = 30/60 (50%)
Query: 401 EKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKEL 460
+++ P+ + E +E+ DED++E+E+ + G E+E E D D E EL
Sbjct: 150 QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSEL 209
Score = 30.8 bits (68), Expect = 4.1
Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 9/65 (13%)
Query: 406 DPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGL 465
D E + EE++DED DED++E E E P + E E+E D D
Sbjct: 149 DQEDNEAPDSEEEDDEDGDEDDEE---------EEENEAGPPEGYEEEEEEEEEEDEDED 199
Query: 466 KKESE 470
+ E E
Sbjct: 200 EDEDE 204
>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 2 [Homo sapiens]
Length = 227
Score = 56.2 bits (134), Expect = 9e-08
Identities = 37/90 (41%), Positives = 50/90 (55%), Gaps = 8/90 (8%)
Query: 385 QEQPVDDAAEVPQREPEKERGDPER-QREMEEEEDEDEDEDEDEDER-QLLGEFEKELEG 442
+E+ +D E + E E E G PE + E EEEE+EDEDEDEDEDE LGE E+E+
Sbjct: 118 EEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGL 177
Query: 443 ILLPSDRDRLRSETEKELDPDGLKKESERD 472
L ++ E + E D D +E E +
Sbjct: 178 SYL------MKEEIQDEEDDDDYVEEGEEE 201
Score = 37.0 bits (84), Expect = 0.057
Identities = 25/120 (20%), Positives = 48/120 (40%), Gaps = 10/120 (8%)
Query: 316 NEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIRSPADLIRFIEELKGG 375
++ +++AP EE E+ D E + P + + + D +E
Sbjct: 108 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 167
Query: 376 TKKGKPNIG----------QEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDE 425
+G+ +G E+ DD E + E E+E G ++ + ED+ E+ED+
Sbjct: 168 LGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 227
Score = 34.3 bits (77), Expect = 0.37
Identities = 26/72 (36%), Positives = 35/72 (48%), Gaps = 11/72 (15%)
Query: 412 EMEEEEDEDEDEDEDEDERQLLG--------EFEKELEGILLPSDRDRLRSET---EKEL 460
+ EEE+DED DED++E+E G E E+E E D D SE E+E+
Sbjct: 116 DSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEV 175
Query: 461 DPDGLKKESERD 472
L KE +D
Sbjct: 176 GLSYLMKEEIQD 187
Score = 31.2 bits (69), Expect = 3.1
Identities = 17/60 (28%), Positives = 30/60 (50%)
Query: 401 EKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKEL 460
+++ P+ + E +E+ DED++E+E+ + G E+E E D D E EL
Sbjct: 109 QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSEL 168
Score = 30.8 bits (68), Expect = 4.1
Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 9/65 (13%)
Query: 406 DPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGL 465
D E + EE++DED DED++E E E P + E E+E D D
Sbjct: 108 DQEDNEAPDSEEEDDEDGDEDDEE---------EEENEAGPPEGYEEEEEEEEEEDEDED 158
Query: 466 KKESE 470
+ E E
Sbjct: 159 EDEDE 163
>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 3 [Homo sapiens]
Length = 220
Score = 56.2 bits (134), Expect = 9e-08
Identities = 37/90 (41%), Positives = 50/90 (55%), Gaps = 8/90 (8%)
Query: 385 QEQPVDDAAEVPQREPEKERGDPER-QREMEEEEDEDEDEDEDEDER-QLLGEFEKELEG 442
+E+ +D E + E E E G PE + E EEEE+EDEDEDEDEDE LGE E+E+
Sbjct: 111 EEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGL 170
Query: 443 ILLPSDRDRLRSETEKELDPDGLKKESERD 472
L ++ E + E D D +E E +
Sbjct: 171 SYL------MKEEIQDEEDDDDYVEEGEEE 194
Score = 37.0 bits (84), Expect = 0.057
Identities = 25/120 (20%), Positives = 48/120 (40%), Gaps = 10/120 (8%)
Query: 316 NEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIRSPADLIRFIEELKGG 375
++ +++AP EE E+ D E + P + + + D +E
Sbjct: 101 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 160
Query: 376 TKKGKPNIG----------QEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDE 425
+G+ +G E+ DD E + E E+E G ++ + ED+ E+ED+
Sbjct: 161 LGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 220
Score = 34.3 bits (77), Expect = 0.37
Identities = 26/72 (36%), Positives = 35/72 (48%), Gaps = 11/72 (15%)
Query: 412 EMEEEEDEDEDEDEDEDERQLLG--------EFEKELEGILLPSDRDRLRSET---EKEL 460
+ EEE+DED DED++E+E G E E+E E D D SE E+E+
Sbjct: 109 DSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEV 168
Query: 461 DPDGLKKESERD 472
L KE +D
Sbjct: 169 GLSYLMKEEIQD 180
Score = 31.2 bits (69), Expect = 3.1
Identities = 17/60 (28%), Positives = 30/60 (50%)
Query: 401 EKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKEL 460
+++ P+ + E +E+ DED++E+E+ + G E+E E D D E EL
Sbjct: 102 QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSEL 161
Score = 30.8 bits (68), Expect = 4.1
Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 9/65 (13%)
Query: 406 DPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGL 465
D E + EE++DED DED++E E E P + E E+E D D
Sbjct: 101 DQEDNEAPDSEEEDDEDGDEDDEE---------EEENEAGPPEGYEEEEEEEEEEDEDED 151
Query: 466 KKESE 470
+ E E
Sbjct: 152 EDEDE 156
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 55.8 bits (133), Expect = 1e-07
Identities = 46/154 (29%), Positives = 64/154 (41%), Gaps = 15/154 (9%)
Query: 317 EPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIRSPADLIRFIEELKGGT 376
E E Q GE P E +PEA A + Q V P +E++G T
Sbjct: 1983 EVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESD-GVEAQPKSEGEEAQEVEGET 2041
Query: 377 KKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEF 436
+K + G QP D E P+ E E + E + E++E E E E ED D ++ GE
Sbjct: 2042 QKTE---GDAQPESDGVEAPEAEEEAQ----EAEGEVQEAEGEAHPESEDVDAQEAEGEA 2094
Query: 437 EKELEGILLPSDRDRLRS-------ETEKELDPD 463
+ E EG+ P + ETE E P+
Sbjct: 2095 QPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPE 2128
Score = 45.8 bits (107), Expect = 1e-04
Identities = 73/290 (25%), Positives = 114/290 (39%), Gaps = 50/290 (17%)
Query: 274 EELQDLGPQVWSETKS-GVAPQKMAGASP-TKDDSKDSDFWKMLNEPEDQAPGGE-EVPA 330
EE Q V ++ KS G Q++ G + T+ D++ E E++A E EV
Sbjct: 2014 EEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQE 2073
Query: 331 EEQDPSPEAAD----SASGAPNDFQNNVQVKVIRSPADLIRFIE--ELKGGTKKGKPNI- 383
E + PE+ D A G V+ A IE E +G + I
Sbjct: 2074 AEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIE 2133
Query: 384 -----GQEQPVDDAAEVPQRE----PEKE-----RGDPERQREME-----EEEDEDEDED 424
G+ QP + E E PE E + E Q E+E E E E + E
Sbjct: 2134 APEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPES 2193
Query: 425 EDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGLK-KESERDRAMLALTSTLN 483
E + + GE + ELEG+ P +E E + +P+G++ E+E + + T
Sbjct: 2194 EGIEAPEAEGEAQPELEGVEAP------EAEEEAQPEPEGVETPEAEGEAQPESEGETQG 2247
Query: 484 KLIKRLEEKQSPEL-------VKKHKKKRVVPK-KPPPSPQPTEEDPEHR 525
E+K SP++ + + VP+ +P P P P + P R
Sbjct: 2248 ------EKKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGDTPHQR 2291
Score = 43.1 bits (100), Expect = 8e-04
Identities = 76/357 (21%), Positives = 137/357 (38%), Gaps = 36/357 (10%)
Query: 288 KSGVAPQKMAGASPTKDDSKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAP 347
+ G+ P G P D+ +D + + LN +D G E A Q+ + +S + A
Sbjct: 1727 EGGLGPGLSQG--PGVDEGEDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAG 1784
Query: 348 NDFQNNVQV-----KVIRSPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQRE--- 399
++ Q + + + L+G G + + E P+ E
Sbjct: 1785 SELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEA 1844
Query: 400 -PEKERGD-PERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETE 457
PE E + PE + + +E E E + E ED + + GE + E E + P ++ E+E
Sbjct: 1845 QPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESE 1904
Query: 458 KELDPDGLKKESERDRAMLAL-TSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQ 516
P+ K+ ++ AL T ++ E Q E + + + P+ Q
Sbjct: 1905 GAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQ 1964
Query: 517 PTEEDPE------HRVRVRVTKLRLGGPNQDLTVLEMKRENPQLKQIEGLVKELLEREGL 570
EE+ + + V V G Q + E+ + + EG ++E E E
Sbjct: 1965 EAEEEAQPESEDVEALEVEVETQEAEGEAQP------ESEDVEAPEAEGEMQE-AEEEAQ 2017
Query: 571 TAAGKIEIKIVRPWAEGTE----EGARWLTDEDTRNLKEIFFNILVPGAEEAQKERQ 623
+ +E +P +EG E EG T+ D + + + P AEE +E +
Sbjct: 2018 PESDGVE---AQPKSEGEEAQEVEGETQKTEGDAQPESD---GVEAPEAEEEAQEAE 2068
Score = 31.2 bits (69), Expect = 3.1
Identities = 32/148 (21%), Positives = 58/148 (39%), Gaps = 1/148 (0%)
Query: 376 TKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGE 435
TK+G G ++ E E +E G + + E E + E+E + E+ + GE
Sbjct: 1306 TKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGE 1365
Query: 436 FEKELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLALTSTLNKLIKRLEEKQSP 495
+E EG+ L ++ + E +GLK+E + + + Q
Sbjct: 1366 GLQE-EGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQED 1424
Query: 496 ELVKKHKKKRVVPKKPPPSPQPTEEDPE 523
+ V++ + R P + TEE E
Sbjct: 1425 DPVQEEEAGRASASAEPCPAEGTEEPTE 1452
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 53.9 bits (128), Expect = 5e-07
Identities = 51/208 (24%), Positives = 90/208 (43%), Gaps = 9/208 (4%)
Query: 399 EPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEK 458
E KE + E + E EEEE+E+E+E+EDE+E + E E+E P + +S K
Sbjct: 1063 ELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIK 1122
Query: 459 ELDPDGLKKESERDRAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPT 518
P LKK+ R R + + T + + E P ++R +P+ P
Sbjct: 1123 RKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEP--FDNSDEERPMPQLEPTCEIEV 1180
Query: 519 EEDPEHRVRVRVTKLRLGGPNQDLTVLEMKRENPQLKQIEGLVKELLEREGLTAAGKIE- 577
EED V + + + G Q T E ++N K + + + G +
Sbjct: 1181 EEDGRKPVLRKAFQHQPGKKRQ--TEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDN 1238
Query: 578 ---IKIVRPWAEGTEEG-ARWLTDEDTR 601
+K + W +GT+ G ++W +++ +
Sbjct: 1239 PEPLKCKQVWPKGTKRGLSKWRQNKERK 1266
Score = 45.8 bits (107), Expect = 1e-04
Identities = 53/201 (26%), Positives = 82/201 (40%), Gaps = 41/201 (20%)
Query: 282 QVWSE-TKSGVAPQKMAGASPTKDDSKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAA 340
QVW + TK G++ + + K + PE E+V EEQ + E
Sbjct: 1246 QVWPKGTKRGLSKWRQ------NKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGK 1299
Query: 341 DSASGAPNDFQNNVQVKVIRSPADLIRFIEELKGGTKKGKPNIGQEQ--------PVDDA 392
S S IR EE+K + G+ + QE+ PV
Sbjct: 1300 TSPSP--------------------IRIEEEVK---ETGEALLPQEENRREETCAPVSPN 1336
Query: 393 AEVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGI-LLPSDRDR 451
P +PE + PE + E EEEE+E+E+E+E E+E + G EK+ +G +
Sbjct: 1337 TS-PGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEE-EGGGNVEKDPDGAKSQEKEEPE 1394
Query: 452 LRSETEKELDPDGLKKESERD 472
+ +E E D ++E E D
Sbjct: 1395 ISTEKEDSARLDDHEEEEEED 1415
Score = 45.8 bits (107), Expect = 1e-04
Identities = 55/210 (26%), Positives = 97/210 (46%), Gaps = 29/210 (13%)
Query: 370 EELKGGTKKGKPNIGQEQPVDDAAEVPQREPE--KERGDPERQREMEEEEDED------E 421
EE +G ++G N+ E+ D A + EPE E+ D R + EEEE+ED E
Sbjct: 1365 EEEEGEEEEGGGNV--EKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNE 1422
Query: 422 DEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAM---LAL 478
D D D+++ + E E E + S ++ L ++ E LD + S + M + L
Sbjct: 1423 DHDADDEDDSHMESAEVEKEELPRESFKEVLENQ-ETFLDLNVQPGHSNPEVLMDCGVDL 1481
Query: 479 TSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTEEDPEHRVRVRVTKLRLGGP 538
T++ N K L PE V + ++PPP Q ++D ++ V T+ + G P
Sbjct: 1482 TASCNSEPKEL--AGDPEAVPES------DEEPPPGEQAQKQDQKNSKEVD-TEFKEGNP 1532
Query: 539 NQDLTVLEMKRENPQLKQIEGLVKELLERE 568
M+ ++ ++ ++ L +E E++
Sbjct: 1533 ------ATMEIDSETVQAVQSLTQESSEQD 1556
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 53.9 bits (128), Expect = 5e-07
Identities = 45/147 (30%), Positives = 82/147 (55%), Gaps = 21/147 (14%)
Query: 380 KPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKE 439
K I ++QP + E+ +RE EKER ER++E+E+E+ E E E E E +R+ E EKE
Sbjct: 491 KLGILEKQPSPE--EIREREREKER---EREKELEKEQ-EQEREKEREKDRERQQEKEKE 544
Query: 440 LEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLALTSTLNKLIKRLEEKQSPELVK 499
LE ++++ R E EKE ++ E+++ + +L K E+++ EL K
Sbjct: 545 LE-----KEQEKQR-EMEKE-------RKQEKEKELERQKEKEKELQKMKEQEKECELEK 591
Query: 500 KHKK--KRVVPKKPPPSPQPTEEDPEH 524
+ +K +++ P++P P +++ E+
Sbjct: 592 EREKLEEKIEPREPNLEPMVEKQESEN 618
Score = 31.2 bits (69), Expect = 3.1
Identities = 35/170 (20%), Positives = 60/170 (35%), Gaps = 17/170 (10%)
Query: 425 EDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLALTSTLNK 484
E D++ L E+ + + R R S K + +R + ++
Sbjct: 897 EAPDQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQ----KPDEQRSEPSAGIPKVTSR 952
Query: 485 LIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTEEDPEH-----------RVRVRVTKL 533
I E + PE +K KK+ + P P+ + R V +
Sbjct: 953 CIDSKEPIERPE--EKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPV 1010
Query: 534 RLGGPNQDLTVLEMKRENPQLKQIEGLVKELLEREGLTAAGKIEIKIVRP 583
R GP + + +MK E Q K+ EG E + + + K E K + P
Sbjct: 1011 RRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPP 1060
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 52.8 bits (125), Expect = 1e-06
Identities = 56/233 (24%), Positives = 97/233 (41%), Gaps = 38/233 (16%)
Query: 326 EEVPAEEQDPSPEAADSASGAPNDFQNNVQ---VKVIRSPADLIRFIEELKGGTKKGKPN 382
EE AE +D AS P DFQ++++ +++ R I E KG + KP
Sbjct: 163 EEASAESEDEMIHPEGVASLLPPDFQSSLERPELELSRHSPRKSSSISEEKGDSDDEKPR 222
Query: 383 IGQEQP----------VDDAAEVPQREPEKE--------RGDPERQREMEEEEDEDEDED 424
G+ + + + ++ + E ++E R D + E EEEE+E+E+ED
Sbjct: 223 KGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEED 282
Query: 425 EDED----------ERQLLGEFEKELEGI------LLPSDRDRLRSETEKELDPDG-LKK 467
++E+ E +L EF++E E I + +R + RS+ ++ L+ G +
Sbjct: 283 DEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTR 342
Query: 468 ESERDRAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTEE 520
E R K +K + E K + K P P+ TE+
Sbjct: 343 SQEEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTED 395
Score = 44.3 bits (103), Expect = 4e-04
Identities = 29/86 (33%), Positives = 50/86 (58%), Gaps = 3/86 (3%)
Query: 388 PVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPS 447
P+ D+ ++ Q+E E+ ER++ +E+E+E++ E E E ER+ + E+E +
Sbjct: 1228 PLTDS-QIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLERE-KRREHSR 1285
Query: 448 DRDRLRSETEKELDPDGLKKESERDR 473
+RDR R E E+E D ++ ERDR
Sbjct: 1286 ERDRER-ERERERDRGDRDRDRERDR 1310
Score = 31.2 bits (69), Expect = 3.1
Identities = 52/235 (22%), Positives = 87/235 (37%), Gaps = 30/235 (12%)
Query: 229 PHPLLRPPPSAA--PQAILCHPSLQPEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSE 286
P PL PPP PQ HP + E V+ Q ++ + E + + W
Sbjct: 1114 PRPLHPPPPPPVQPPQ----HPRAEQREQERAVREQWAEREREMERRERTRS--EREWDR 1167
Query: 287 TKSGVAPQKMAGASPTKDDSKDSDFWKMLNEPEDQAPGGEEVPAEEQDP---SPEAADSA 343
K P+ S ++D + + E + EE PA+ D +AA
Sbjct: 1168 DKVREGPRSR---SRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCI 1224
Query: 344 SGAPNDFQNNVQVKVIRSPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKE 403
P VQ + R+ E K K+ K +EQ + +R + E
Sbjct: 1225 YWLPLTDSQIVQKEAERA--------ERAKEREKRRKEQEEEEQKEREKEAERERNRQLE 1276
Query: 404 RGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEK 458
R E++RE E D + + + + D + E++ E R+R R +T++
Sbjct: 1277 R---EKRREHSRERDRERERERERDRGDRDRDRERDRE-----RGRERDRRDTKR 1323
Score = 30.8 bits (68), Expect = 4.1
Identities = 38/165 (23%), Positives = 59/165 (35%), Gaps = 25/165 (15%)
Query: 386 EQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILL 445
+ P AE ++E ER+REME E + + D D K EG
Sbjct: 1126 QPPQHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRD---------KVREGPRS 1176
Query: 446 PS-DRDRLRSETEKELDPDGLKKESERDRAMLALTSTLNKLIKRL--------------- 489
S RDR R E K + KKE ++ L L + K
Sbjct: 1177 RSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQ 1236
Query: 490 EEKQSPELVKKHKKKRVVPKKPPPSPQPTEEDPEHRVRVRVTKLR 534
+E + E K+ +K+R ++ + E + E ++ K R
Sbjct: 1237 KEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRR 1281
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 52.4 bits (124), Expect = 1e-06
Identities = 66/255 (25%), Positives = 96/255 (37%), Gaps = 49/255 (19%)
Query: 293 PQKMAGASPTKDDSKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQN 352
P+KMA P K+ +DS+ +M + ED + GEEV ++ AA SA
Sbjct: 14 PKKMA--PPPKEVEEDSEDEEMSEDEEDDS-SGEEVVIPQKKGKKAAATSAKKVVVSPTK 70
Query: 353 NVQV-------------KVIRSPADLIRFIEELKGGTKKGKPNIGQEQ-----PVDDAAE 394
V V K +PA + + K T GK + P A
Sbjct: 71 KVAVATPAKKAAVTPGKKAAATPAK--KTVTPAKAVTTPGKKGATPGKALVATPGKKGAA 128
Query: 395 VPQR------EPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSD 448
+P + +KE D E + EE+E++DEDEDEDEDE E P+
Sbjct: 129 IPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEI----EPAAMKAAAAAPAS 184
Query: 449 RDRLRSETEKELDPDGLKKESERDRAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVP 508
D + E + D D +++ + AM + +P KK K V
Sbjct: 185 EDEDDEDDEDDEDDDDDEEDDSEEEAM----------------ETTPAKGKKAAKVVPVK 228
Query: 509 KKPPPSPQPTEEDPE 523
K + EED E
Sbjct: 229 AKNVAEDEDEEEDDE 243
Score = 44.3 bits (103), Expect = 4e-04
Identities = 48/217 (22%), Positives = 94/217 (43%), Gaps = 25/217 (11%)
Query: 288 KSGVAPQKMA--GASPTKDDSKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASG 345
K P K A G + K+DS + + ++ E+ E+ +E + P A +A+
Sbjct: 125 KGAAIPAKGAKNGKNAKKEDSDEEED----DDSEEDEEDDEDEDEDEDEIEPAAMKAAAA 180
Query: 346 AP----NDFQNNVQVKVIRSPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPE 401
AP D +++ + + E ++ KGK AA+V + +
Sbjct: 181 APASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKK----------AAKVVPVKAK 230
Query: 402 KERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELD 461
D + + + E+E+D+D+++DED+D+ E E+E E + + R + +++
Sbjct: 231 NVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAA 290
Query: 462 PDGLKKESERDRAMLALTSTLNKLIKRLE-EKQSPEL 497
P+ K++ E T+ N + L K +PEL
Sbjct: 291 PEAKKQKVEGTEP----TTAFNLFVGNLNFNKSAPEL 323
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 52.0 bits (123), Expect = 2e-06
Identities = 56/225 (24%), Positives = 96/225 (42%), Gaps = 52/225 (23%)
Query: 302 TKDDSKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIRS 361
+ +DS+DSDF Q G E +E +D SA A
Sbjct: 1337 SSEDSEDSDF---------QESGVSEEVSESEDEQRPRTRSAKKAE-------------- 1373
Query: 362 PADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDE 421
+EE + K+ K + D ++E E+E E++ E EEEE+E+E
Sbjct: 1374 -------LEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEE---EKEEEEEEEEEEEE 1423
Query: 422 DEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKEL--DPDGLKKESERDRAMLALT 479
+E+++ D+ + G+ K++ IL D+LR+ET+ L + + K+ +ER+R L
Sbjct: 1424 EEEDENDDSKSPGKGRKKIRKIL---KDDKLRTETQNALKEEEERRKRIAEREREREKLR 1480
Query: 480 STL-------------NKLIKRLEEKQSPELVKKHKKKRVVPKKP 511
+ KL+ +E+ LV+ H + V+ KP
Sbjct: 1481 EVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVH-RNMVIKLKP 1524
Score = 35.4 bits (80), Expect = 0.17
Identities = 42/201 (20%), Positives = 84/201 (41%), Gaps = 39/201 (19%)
Query: 348 NDFQNNVQVKVIRSPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDP 407
ND +N + K++ +EE+K + ++P ++ + ++ E+ GD
Sbjct: 1227 NDPENRIAKKML---------LEEIKANLSSDEDGSSDDEP-EEGKKRTGKQNEENPGDE 1276
Query: 408 ERQREMEEEEDEDEDED-------------------EDEDERQLLGEFEKELEGILLPSD 448
E + ++ E D D +E E +E++ + KE++G +
Sbjct: 1277 EAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKG----RN 1332
Query: 449 RDRLRSETEKELD--PDGLKKE-SERDRAMLALTSTLNKLIKRLEEKQ-SPELVKKHKKK 504
R ++ SE ++ D G+ +E SE + T + K LEE Q S + KK ++
Sbjct: 1333 RRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKK--AELEENQRSYKQKKKRRRI 1390
Query: 505 RVVPKKPPPSPQPTEEDPEHR 525
+V + +EE+ E +
Sbjct: 1391 KVQEDSSSENKSNSEEEEEEK 1411
Score = 30.0 bits (66), Expect = 7.0
Identities = 29/133 (21%), Positives = 58/133 (43%), Gaps = 14/133 (10%)
Query: 376 TKKGKPNIGQEQPVDDAAEVPQREPEKERG-DPERQREMEEEEDEDEDEDEDEDERQLLG 434
TKK PN +D E ++G D + + ++ ++ D+ E + ER+
Sbjct: 799 TKKRIPNTKDFDSSED-------EKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFS 851
Query: 435 EFEKELE-GILLPSDRDRLRSETEKELDPDGLKKESERDRAMLALTSTLNKLIKRLEEKQ 493
E ++ + RDRL + + DG+ K S ++++ +L ++ K E K+
Sbjct: 852 SAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSL-----EVRKVAETKE 906
Query: 494 SPELVKKHKKKRV 506
+ +K K+V
Sbjct: 907 KSKHLKTKTCKKV 919
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 52.0 bits (123), Expect = 2e-06
Identities = 56/225 (24%), Positives = 96/225 (42%), Gaps = 52/225 (23%)
Query: 302 TKDDSKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIRS 361
+ +DS+DSDF Q G E +E +D SA A
Sbjct: 1375 SSEDSEDSDF---------QESGVSEEVSESEDEQRPRTRSAKKAE-------------- 1411
Query: 362 PADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDE 421
+EE + K+ K + D ++E E+E E++ E EEEE+E+E
Sbjct: 1412 -------LEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEE---EKEEEEEEEEEEEE 1461
Query: 422 DEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKEL--DPDGLKKESERDRAMLALT 479
+E+++ D+ + G+ K++ IL D+LR+ET+ L + + K+ +ER+R L
Sbjct: 1462 EEEDENDDSKSPGKGRKKIRKIL---KDDKLRTETQNALKEEEERRKRIAEREREREKLR 1518
Query: 480 STL-------------NKLIKRLEEKQSPELVKKHKKKRVVPKKP 511
+ KL+ +E+ LV+ H + V+ KP
Sbjct: 1519 EVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVH-RNMVIKLKP 1562
Score = 35.4 bits (80), Expect = 0.17
Identities = 42/201 (20%), Positives = 84/201 (41%), Gaps = 39/201 (19%)
Query: 348 NDFQNNVQVKVIRSPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDP 407
ND +N + K++ +EE+K + ++P ++ + ++ E+ GD
Sbjct: 1265 NDPENRIAKKML---------LEEIKANLSSDEDGSSDDEP-EEGKKRTGKQNEENPGDE 1314
Query: 408 ERQREMEEEEDEDEDED-------------------EDEDERQLLGEFEKELEGILLPSD 448
E + ++ E D D +E E +E++ + KE++G +
Sbjct: 1315 EAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKG----RN 1370
Query: 449 RDRLRSETEKELD--PDGLKKE-SERDRAMLALTSTLNKLIKRLEEKQ-SPELVKKHKKK 504
R ++ SE ++ D G+ +E SE + T + K LEE Q S + KK ++
Sbjct: 1371 RRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKK--AELEENQRSYKQKKKRRRI 1428
Query: 505 RVVPKKPPPSPQPTEEDPEHR 525
+V + +EE+ E +
Sbjct: 1429 KVQEDSSSENKSNSEEEEEEK 1449
Score = 30.0 bits (66), Expect = 7.0
Identities = 29/133 (21%), Positives = 58/133 (43%), Gaps = 14/133 (10%)
Query: 376 TKKGKPNIGQEQPVDDAAEVPQREPEKERG-DPERQREMEEEEDEDEDEDEDEDERQLLG 434
TKK PN +D E ++G D + + ++ ++ D+ E + ER+
Sbjct: 837 TKKRIPNTKDFDSSED-------EKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFS 889
Query: 435 EFEKELE-GILLPSDRDRLRSETEKELDPDGLKKESERDRAMLALTSTLNKLIKRLEEKQ 493
E ++ + RDRL + + DG+ K S ++++ +L ++ K E K+
Sbjct: 890 SAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSL-----EVRKVAETKE 944
Query: 494 SPELVKKHKKKRV 506
+ +K K+V
Sbjct: 945 KSKHLKTKTCKKV 957
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 51.2 bits (121), Expect = 3e-06
Identities = 81/375 (21%), Positives = 150/375 (40%), Gaps = 52/375 (13%)
Query: 252 PEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGASPTKDDSKDSDF 311
PE+ + V+ +A S ++E +V S K+ SPTK+++K +
Sbjct: 601 PEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKA---------KSPTKEEAKSPEK 651
Query: 312 WKMLNEPEDQAPGGEEVPAEEQDPSPEAADS----ASGAPNDFQNNVQVKVIRSPADLIR 367
K + E ++P + P + + SPE A S + +P ++ V+ + +SP
Sbjct: 652 AKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEA-KSPEKAKS 710
Query: 368 FIEELKGGTKKGKPNIGQEQPVDDAAEVPQRE----PEKERGDPERQREME--------- 414
++E +K K + +E + A+ P +E PEK + PE+ + ++
Sbjct: 711 PVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAK-SPEKAKTLDVKSPEAKTP 769
Query: 415 -EEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETE--KELDPDGLKKESER 471
+EE + E + + E K E P D E E K+ + KE E+
Sbjct: 770 AKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEK 829
Query: 472 DRAMLALTSTLNKLIKRLEEKQSPEL----VKKHKKKRVVPKKPPPSP-----------Q 516
+ + + + K+ EE+++P KK KK PKK P P +
Sbjct: 830 PQEV-----KVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEK 884
Query: 517 PTEEDPEHRVRVRVTKLRLGGPNQDLTV-LEMKRENPQLKQIEGLVKELLEREGLTAAGK 575
P E E + K ++ P ++ +E+K + ++ E KE + + +
Sbjct: 885 PKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKP 944
Query: 576 IEIKIVRPWAEGTEE 590
E K P + T+E
Sbjct: 945 AEKKEAAPEKKDTKE 959
Score = 42.7 bits (99), Expect = 0.001
Identities = 31/136 (22%), Positives = 63/136 (46%), Gaps = 5/136 (3%)
Query: 292 APQKMAGASPTKDDSKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQ 351
A ++ A A+P ++ KDS K P+ +AP + E+++P+ E + +
Sbjct: 842 AEEEKAPATPKTEEKKDS---KKEEAPKKEAP--KPKVEEKKEPAVEKPKESKVEAKKEE 896
Query: 352 NNVQVKVIRSPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQR 411
+ KV + +E + K K + +++P D A+ P + EK+ PE++
Sbjct: 897 AEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKD 956
Query: 412 EMEEEEDEDEDEDEDE 427
EE+ + E++ + E
Sbjct: 957 TKEEKAKKPEEKPKTE 972
Score = 42.4 bits (98), Expect = 0.001
Identities = 67/319 (21%), Positives = 127/319 (39%), Gaps = 35/319 (10%)
Query: 292 APQKMAGASPTKDDSKDSDFWKMLNEPEDQAPGGEEV--------PAEEQDPSPEAADSA 343
+P+K SP K+++K + PE ++P EE P + + P+ E A S
Sbjct: 546 SPEK--AKSPAKEEAK--------SPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSP 595
Query: 344 SGAPNDFQNNVQVK-VIRSPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQ--REP 400
+ A + + VK +SPA+ ++E + K + P + A+ P+ + P
Sbjct: 596 AEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSP 655
Query: 401 EKERG-DPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKE 459
EKE PE+ + + E + ++ + + + K E P + E K
Sbjct: 656 EKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAE-----AKSPEKAKSPVKEEAKSPEKAKS 710
Query: 460 LDPDGLKKESERDRAMLALTSTLNKLIKRL-EEKQSPELVKKHKKKRVVPKKPPPSPQPT 518
+ K + + T K + EE +SPE K +K + + K P + P
Sbjct: 711 PVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPA 770
Query: 519 EEDPEHRVRVRVTKLRLGGPNQDLTVLEMKRENPQLKQIEGLVKELLEREGLTAAGK--- 575
+E+ K + P ++ K ++P + + KE+ ++E + + K
Sbjct: 771 KEEARSPADKFPEKAK--SPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEE 828
Query: 576 --IEIKIVRPWAEGTEEGA 592
E+K+ P + EE A
Sbjct: 829 KPQEVKVKEPPKKAEEEKA 847
Score = 34.3 bits (77), Expect = 0.37
Identities = 34/160 (21%), Positives = 62/160 (38%), Gaps = 22/160 (13%)
Query: 370 EELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDE 429
E++K K K + E+ ++ + E+E+ E + + EE +E+E E +E+
Sbjct: 442 EKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEET 501
Query: 430 RQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLALTSTLNKLIKRL 489
+ E S +S ++E K E++ A K
Sbjct: 502 KSPPAE--------EAASPEKEAKSPVKEEAKSPAEAKSPEKEEA------------KSP 541
Query: 490 EEKQSPELVKKHKKKRVVPKKPPPSPQPTEEDPEHRVRVR 529
E +SPE K K+ K PP + P +E+ + V+
Sbjct: 542 AEVKSPEKAKSPAKEEA--KSPPEAKSPEKEEAKSPAEVK 579
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 50.8 bits (120), Expect = 4e-06
Identities = 46/150 (30%), Positives = 69/150 (46%), Gaps = 34/150 (22%)
Query: 378 KGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFE 437
K K + ++ + +RE EKERG + R+ E E+D ++D+++D + E E
Sbjct: 385 KEKERVKEKDREKEREREKEREKEKERG-KNKDRDKEREKDREKDKEKDRER-----ERE 438
Query: 438 KELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLALTSTLNKLIKRLEEKQSPEL 497
KE E DRD+ E EKE D + KE E+DR+ K ++EK+
Sbjct: 439 KEHE-----KDRDK---EKEKEQDKE---KEREKDRS------------KEIDEKR---- 471
Query: 498 VKKHKKKRVVPKKPPPSPQPTEEDPEHRVR 527
KK KK R P+ S + E R R
Sbjct: 472 -KKDKKSRTPPRSYNASRRSRSSSRERRRR 500
Score = 38.1 bits (87), Expect = 0.026
Identities = 38/173 (21%), Positives = 72/173 (41%), Gaps = 18/173 (10%)
Query: 370 EELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDE 429
+E + G K + ++ D + +RE EKE E+ R+ E+E+++D++++ ++D
Sbjct: 407 KEKERGKNKDRDKEREKDREKDKEKDREREREKEH---EKDRDKEKEKEQDKEKEREKDR 463
Query: 430 RQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLALTSTLNKLIKRL 489
+ + E K+ + R RS ++ R + + +K IKR
Sbjct: 464 SKEIDEKRKKDK-----KSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRK 518
Query: 490 EEKQ-SPELVKKHKKKRVVPKKPPPSPQPTEEDPEHRVRVRVTKLRLGGPNQD 541
+ SP K KKR + + E R R R T +R ++D
Sbjct: 519 SSRSPSPRSRNKKDKKR---------EKERDHISERRERERSTSMRKSSNDRD 562
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 50.8 bits (120), Expect = 4e-06
Identities = 46/150 (30%), Positives = 69/150 (46%), Gaps = 34/150 (22%)
Query: 378 KGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFE 437
K K + ++ + +RE EKERG + R+ E E+D ++D+++D + E E
Sbjct: 269 KEKERVKEKDREKEREREKEREKEKERG-KNKDRDKEREKDREKDKEKDRER-----ERE 322
Query: 438 KELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLALTSTLNKLIKRLEEKQSPEL 497
KE E DRD+ E EKE D + KE E+DR+ K ++EK+
Sbjct: 323 KEHE-----KDRDK---EKEKEQDKE---KEREKDRS------------KEIDEKR---- 355
Query: 498 VKKHKKKRVVPKKPPPSPQPTEEDPEHRVR 527
KK KK R P+ S + E R R
Sbjct: 356 -KKDKKSRTPPRSYNASRRSRSSSRERRRR 384
Score = 38.1 bits (87), Expect = 0.026
Identities = 38/173 (21%), Positives = 72/173 (41%), Gaps = 18/173 (10%)
Query: 370 EELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDE 429
+E + G K + ++ D + +RE EKE E+ R+ E+E+++D++++ ++D
Sbjct: 291 KEKERGKNKDRDKEREKDREKDKEKDREREREKEH---EKDRDKEKEKEQDKEKEREKDR 347
Query: 430 RQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLALTSTLNKLIKRL 489
+ + E K+ + R RS ++ R + + +K IKR
Sbjct: 348 SKEIDEKRKKDK-----KSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRK 402
Query: 490 EEKQ-SPELVKKHKKKRVVPKKPPPSPQPTEEDPEHRVRVRVTKLRLGGPNQD 541
+ SP K KKR + + E R R R T +R ++D
Sbjct: 403 SSRSPSPRSRNKKDKKR---------EKERDHISERRERERSTSMRKSSNDRD 446
>gi|8923771 ELG protein isoform b [Homo sapiens]
Length = 340
Score = 50.4 bits (119), Expect = 5e-06
Identities = 59/246 (23%), Positives = 95/246 (38%), Gaps = 37/246 (15%)
Query: 406 DPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGL 465
+ E + E EEEE+E+ED+D D D+R ++ E+ +EL + P +R R + D D +
Sbjct: 64 EEEEEEEEEEEEEEEEDQDMDADDRVVV-EYHEELPALKQPRERSASRRSSASSSDSDEM 122
Query: 466 KKESE----------RDRAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPS- 514
+ E + M + +K + + V K + K PP
Sbjct: 123 DYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEK 182
Query: 515 ----------------PQPTEEDPEHRVRVRVTKLRLGGPNQDLTVLEMKRENPQLKQIE 558
P+P + +R R+ K R P + + + R P
Sbjct: 183 FADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGK-RPHSPEKAFSSNPVVRREPSSDVHS 241
Query: 559 GLVKELLEREGLTAAGKIEIKIVRPWAEGTEEGARWLTDEDTRNLKEIFFNILVPGAEEA 618
L + +GL A + E K W T G+ T E +N K++ + PGAEE
Sbjct: 242 RLGVPRQDSKGLYADTR-EKKSGNLW---TRLGSAPKTKE--KNTKKV--DHRAPGAEED 293
Query: 619 QKERQR 624
E QR
Sbjct: 294 DSELQR 299
>gi|166295179 ELG protein isoform a [Homo sapiens]
Length = 620
Score = 50.4 bits (119), Expect = 5e-06
Identities = 59/246 (23%), Positives = 95/246 (38%), Gaps = 37/246 (15%)
Query: 406 DPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGL 465
+ E + E EEEE+E+ED+D D D+R ++ E+ +EL + P +R R + D D +
Sbjct: 344 EEEEEEEEEEEEEEEEDQDMDADDRVVV-EYHEELPALKQPRERSASRRSSASSSDSDEM 402
Query: 466 KKESE----------RDRAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPS- 514
+ E + M + +K + + V K + K PP
Sbjct: 403 DYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEK 462
Query: 515 ----------------PQPTEEDPEHRVRVRVTKLRLGGPNQDLTVLEMKRENPQLKQIE 558
P+P + +R R+ K R P + + + R P
Sbjct: 463 FADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGK-RPHSPEKAFSSNPVVRREPSSDVHS 521
Query: 559 GLVKELLEREGLTAAGKIEIKIVRPWAEGTEEGARWLTDEDTRNLKEIFFNILVPGAEEA 618
L + +GL A + E K W T G+ T E +N K++ + PGAEE
Sbjct: 522 RLGVPRQDSKGLYADTR-EKKSGNLW---TRLGSAPKTKE--KNTKKV--DHRAPGAEED 573
Query: 619 QKERQR 624
E QR
Sbjct: 574 DSELQR 579
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 49.3 bits (116), Expect = 1e-05
Identities = 33/131 (25%), Positives = 58/131 (44%), Gaps = 3/131 (2%)
Query: 330 AEEQDPSPEAADSASGAPNDFQNNVQVKVIRSPADLIRFIEELKGGTKKGKPNIGQEQPV 389
A E S E P D + V+V RS + +E+ + I +
Sbjct: 201 AAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEE 260
Query: 390 DDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDR 449
D+ E + E E++ + E + E EEEE+E+E+E+E+E+E + E E+ ++ D
Sbjct: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEE---EEEEAAPDVIFQEDT 317
Query: 450 DRLRSETEKEL 460
++ EL
Sbjct: 318 SHTSAQKAPEL 328
Score = 41.6 bits (96), Expect = 0.002
Identities = 26/82 (31%), Positives = 46/82 (56%), Gaps = 4/82 (4%)
Query: 387 QPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLP 446
Q ++DAA E K++G + E +EEE+E+E+E+E+++E + E E+E E
Sbjct: 238 QSLEDAAS---EESSKQKGILSHEEE-DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEE 293
Query: 447 SDRDRLRSETEKELDPDGLKKE 468
+ + E E+E PD + +E
Sbjct: 294 EEEEEEEEEEEEEAAPDVIFQE 315
Score = 37.0 bits (84), Expect = 0.057
Identities = 34/156 (21%), Positives = 60/156 (38%), Gaps = 18/156 (11%)
Query: 317 EPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIRSPADLIRFIEELKGGT 376
+PED E QD P++ + A+ + Q + EE
Sbjct: 217 QPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSH------------EEEDEEE 264
Query: 377 KKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEF 436
++ + +++ ++ E + E E+E + E + E EEEE+ D ED +
Sbjct: 265 EEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQK 324
Query: 437 EKELEGILLPSDRD------RLRSETEKELDPDGLK 466
EL G PS + +RS+ +K+ D K
Sbjct: 325 APELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRK 360
Score = 32.7 bits (73), Expect = 1.1
Identities = 35/176 (19%), Positives = 67/176 (38%), Gaps = 25/176 (14%)
Query: 264 DSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGASPTKDDSKDSDFWKMLNEPEDQAP 323
D+++ + E QDL PQ + S + ++ S ++D ++ + + E E++
Sbjct: 220 DAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEE 279
Query: 324 GGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIRSPADLIRFIEELKGGTKKGKPNI 383
EE EE++ E + + + D+I F E+ + + P +
Sbjct: 280 EEEEEEEEEEEEEEEEEEEEEEEEEE----------EAAPDVI-FQEDTSHTSAQKAPEL 328
Query: 384 GQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKE 439
R PE PE +E D+D+DED + + E E +
Sbjct: 329 --------------RGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEMQ 370
Score = 30.0 bits (66), Expect = 7.0
Identities = 34/175 (19%), Positives = 69/175 (39%), Gaps = 31/175 (17%)
Query: 365 LIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERG-DPERQREMEEEEDEDE-- 421
++ ++E G + G +DA EV + E+ + P+ + EE +
Sbjct: 194 IVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKG 253
Query: 422 ----DEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLA 477
+E+++E+E + E E E E + + E E+E + + ++E E +
Sbjct: 254 ILSHEEEDEEEEEEEEEEEEDEEE-----EEEEEEEEEEEEEEEEEEEEEEEEEE----- 303
Query: 478 LTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPP--SPQPTEEDPEHRVRVRV 530
EE+ +P+++ + +K P P+ PE+ V V V
Sbjct: 304 ------------EEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEV 346
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 49.3 bits (116), Expect = 1e-05
Identities = 63/284 (22%), Positives = 113/284 (39%), Gaps = 38/284 (13%)
Query: 365 LIRFIEELKGGTKKGKPNIGQEQPVDDAAE----VPQREPEKERGDPERQREMEEEEDED 420
L EEL K+ K +E+ + AE ++ P K ++ E E+EE+E
Sbjct: 473 LTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEG 532
Query: 421 EDEDEDEDERQLLGEFEK---ELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLA 477
++E+E+EDE + E+ E EG + ++ ETE E + + + + E
Sbjct: 533 QEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEE------- 585
Query: 478 LTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTEEDP-EHRVRVRVTKLRLG 536
K++EEK K+ +KP + P + P E + + V K
Sbjct: 586 ---------KKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPK---- 632
Query: 537 GPNQDLTVLEMKRENPQLKQIEGLVKELLEREGLTAAGK--IEIKIVRPWAEGTEEGARW 594
P ++ + + + K + K +E +G + K +E K P + E A+
Sbjct: 633 SPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKS 692
Query: 595 LT--------DEDTRNLKEIFFNILVPGAEEAQKERQRQKELES 630
+E+ + +KE V EE K+ +K+ ES
Sbjct: 693 KAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAES 736
Score = 32.3 bits (72), Expect = 1.4
Identities = 30/143 (20%), Positives = 61/143 (42%), Gaps = 8/143 (5%)
Query: 285 SETKSGVAPQKMAGASPTKDDSKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSAS 344
S+ + G QK K+ K+ K +P+D VP +++ SP ++ +
Sbjct: 692 SKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKD-------VPEKKKAESPVKEEAVA 744
Query: 345 GAPNDFQNNVQVKVIRSPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKER 404
+V+V + + + + +++ K K G +E+ D A+ ++E
Sbjct: 745 EVVT-ITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVN 803
Query: 405 GDPERQREMEEEEDEDEDEDEDE 427
G+ E + E+E+E E E+E
Sbjct: 804 GEVEGKEEVEQETKEKGSGREEE 826
Score = 30.8 bits (68), Expect = 4.1
Identities = 34/152 (22%), Positives = 67/152 (44%), Gaps = 27/152 (17%)
Query: 329 PAEEQDPSP------EAADSASGAPNDFQNNVQVKVIRSPADLIRFIEELKGGTKKGKPN 382
P EE+ SP E + + + + + V +SP +EE K + GK
Sbjct: 647 PVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSP------VEEAKSKAEVGK-- 698
Query: 383 IGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEG 442
G++ + E EKE + ++ ++E++E++ +D E + + E
Sbjct: 699 -GEQ----------KEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVV 747
Query: 443 ILLPSDRDRLRSETEKELDPDGLKKESERDRA 474
+ S + L ET++E P L++E E+++A
Sbjct: 748 TITKSVKVHLEKETKEEGKP--LQQEKEKEKA 777
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 49.3 bits (116), Expect = 1e-05
Identities = 63/284 (22%), Positives = 113/284 (39%), Gaps = 38/284 (13%)
Query: 365 LIRFIEELKGGTKKGKPNIGQEQPVDDAAE----VPQREPEKERGDPERQREMEEEEDED 420
L EEL K+ K +E+ + AE ++ P K ++ E E+EE+E
Sbjct: 97 LTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEG 156
Query: 421 EDEDEDEDERQLLGEFEK---ELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLA 477
++E+E+EDE + E+ E EG + ++ ETE E + + + + E
Sbjct: 157 QEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEE------- 209
Query: 478 LTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTEEDP-EHRVRVRVTKLRLG 536
K++EEK K+ +KP + P + P E + + V K
Sbjct: 210 ---------KKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPK---- 256
Query: 537 GPNQDLTVLEMKRENPQLKQIEGLVKELLEREGLTAAGK--IEIKIVRPWAEGTEEGARW 594
P ++ + + + K + K +E +G + K +E K P + E A+
Sbjct: 257 SPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKS 316
Query: 595 LT--------DEDTRNLKEIFFNILVPGAEEAQKERQRQKELES 630
+E+ + +KE V EE K+ +K+ ES
Sbjct: 317 KAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAES 360
Score = 32.3 bits (72), Expect = 1.4
Identities = 30/143 (20%), Positives = 61/143 (42%), Gaps = 8/143 (5%)
Query: 285 SETKSGVAPQKMAGASPTKDDSKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSAS 344
S+ + G QK K+ K+ K +P+D VP +++ SP ++ +
Sbjct: 316 SKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKD-------VPEKKKAESPVKEEAVA 368
Query: 345 GAPNDFQNNVQVKVIRSPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKER 404
+V+V + + + + +++ K K G +E+ D A+ ++E
Sbjct: 369 EVVT-ITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVN 427
Query: 405 GDPERQREMEEEEDEDEDEDEDE 427
G+ E + E+E+E E E+E
Sbjct: 428 GEVEGKEEVEQETKEKGSGREEE 450
Score = 30.8 bits (68), Expect = 4.1
Identities = 34/152 (22%), Positives = 67/152 (44%), Gaps = 27/152 (17%)
Query: 329 PAEEQDPSP------EAADSASGAPNDFQNNVQVKVIRSPADLIRFIEELKGGTKKGKPN 382
P EE+ SP E + + + + + V +SP +EE K + GK
Sbjct: 271 PVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSP------VEEAKSKAEVGK-- 322
Query: 383 IGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEG 442
G++ + E EKE + ++ ++E++E++ +D E + + E
Sbjct: 323 -GEQ----------KEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVV 371
Query: 443 ILLPSDRDRLRSETEKELDPDGLKKESERDRA 474
+ S + L ET++E P L++E E+++A
Sbjct: 372 TITKSVKVHLEKETKEEGKP--LQQEKEKEKA 401
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 48.9 bits (115), Expect = 1e-05
Identities = 73/337 (21%), Positives = 139/337 (41%), Gaps = 60/337 (17%)
Query: 261 RQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQ-KMAGASPTKDDSKDSDFWKMLNEPE 319
++ + + D EEL+D S++K P+ +M S DD N+
Sbjct: 101 QKGKKQSFDDNDSEELEDKD----SKSKKTAKPKVEMYSGSDDDDD---------FNKLP 147
Query: 320 DQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIRSPADLIRFIEELKGGTKKG 379
+A G + ++ D S E D++ + N + S + F++ KG K
Sbjct: 148 KKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGE---SGDESDEFLQSRKGQKKNQ 204
Query: 380 K----PNIGQEQPVDDA-----------AEVPQREPEKERGDPERQREMEEEEDEDEDED 424
K PNI DDA AE +RE +K + + R+++E+E+ + +
Sbjct: 205 KNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKK 264
Query: 425 EDEDERQLLGEFEKE-------LEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLA 477
+ +++ +FE+E ++ ++P+ ++ + T E D +G KK+ ++
Sbjct: 265 DQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKK----- 319
Query: 478 LTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTEEDPEHRVRVRVTKLR--- 534
K+ EK+ E KK + K + +E+ E + R +++
Sbjct: 320 ---------KKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLE 370
Query: 535 -LGGPNQDLTVLEM-KRENPQLKQIEGLVKELLEREG 569
L ++ LE KRE + K+ E KE L++EG
Sbjct: 371 ELEAKRKEEERLEQEKRERKKQKEKER--KERLKKEG 405
Score = 44.3 bits (103), Expect = 4e-04
Identities = 26/84 (30%), Positives = 40/84 (47%)
Query: 391 DAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRD 450
+ E P+ E E+E + E + EEEE+E E E + DE EK+ L
Sbjct: 526 EVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSK 585
Query: 451 RLRSETEKELDPDGLKKESERDRA 474
+ S++E + D D K+E D+A
Sbjct: 586 EMSSDSEYDSDDDRTKEERAYDKA 609
Score = 39.7 bits (91), Expect = 0.009
Identities = 71/368 (19%), Positives = 137/368 (37%), Gaps = 31/368 (8%)
Query: 293 PQKMAGASPTKDDSKDSDFWKMLNEPEDQAPGGEEVPAEEQD----PSPEAADSASGAPN 348
PQK G + +D D +L E E+ + + + A+ + P+ + +
Sbjct: 37 PQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDK 96
Query: 349 DFQNNVQVKVIRSPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPE 408
+ K D ++ K KP + DD + + P+K +G +
Sbjct: 97 KKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDF-NKLPKKAKGKAQ 155
Query: 409 RQREMEEEEDEDEDEDEDEDERQLL---GEFEKELEGILLPSDRDRLRSETEKELDPDGL 465
+ + + +EDED + ER + GE E + L + + + +K +
Sbjct: 156 KSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFL---QSRKGQKKNQKNKPGPNI 212
Query: 466 KKESERDRAMLALTSTLNKLIKRLE---EKQSPELVKKHKKKRVVPKKPPPSPQPTEEDP 522
+ +E D A + + K ++ E +K+ E K K K + Q +++
Sbjct: 213 ESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKES 272
Query: 523 EHRVRVRVTKLRLGGPNQDLTVLEMKRENPQL-------------KQIEGLVKELLEREG 569
+ + K ++ + E K E P K+ + KE E+E
Sbjct: 273 QRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEK 332
Query: 570 LTAAGKIEIKIVRP-WAEGTEEGARWLTDEDTR--NLKEIFFNILVPGA-EEAQKERQRQ 625
K +K ++ A+ EE R +E+ R L+E+ E+ ++ER++Q
Sbjct: 333 KKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQ 392
Query: 626 KELESNYR 633
KE E R
Sbjct: 393 KEKERKER 400
Score = 36.2 bits (82), Expect = 0.097
Identities = 34/128 (26%), Positives = 60/128 (46%), Gaps = 12/128 (9%)
Query: 385 QEQPVDDA------AEVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEK 438
+E+ +DA A E EK G+ E E+E+E+E+E+E++ + E E+
Sbjct: 494 EEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEE--SEEEE 551
Query: 439 ELEGILLPSDRDRLRSETEKELD-PDGLKKESERDRAMLALTSTLNKLIKRLEEKQSPEL 497
E EG S+ D E EK D D K ++ ++ S + R +E+++ +
Sbjct: 552 EEEGESEGSEGD---EEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDK 608
Query: 498 VKKHKKKR 505
K+ +KR
Sbjct: 609 AKRRIEKR 616
Score = 34.7 bits (78), Expect = 0.28
Identities = 57/281 (20%), Positives = 118/281 (41%), Gaps = 35/281 (12%)
Query: 378 KGKPNIGQEQPVDD------AAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQ 431
K + N ++ DD AAE+ KE+ +P++ + +++E + +D DED+ ++
Sbjct: 3 KKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQ-EPQKSKGKKKKEKKKQDFDEDDILKE 61
Query: 432 LLGEFEKELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLALTSTLNKLIKRLEE 491
L E E +GI +DR+ + + + + + K+ ++ S + + LE+
Sbjct: 62 -LEELSLEAQGI--KADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELED 118
Query: 492 KQSPELVKKHKKKRV--------------VPKKPPPSPQP-------TEEDPEHRVRVRV 530
K S KK K +V +PKK Q +EED ++ +++
Sbjct: 119 KDSKS--KKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKE 176
Query: 531 -TKLRLGGPNQDLTVLEMKRENPQLKQIEGLVKELLEREGLTAAGKIEIKIVRPWAEGTE 589
+++ G + D + ++ Q K + +E +IK V +
Sbjct: 177 RSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKK 236
Query: 590 EGARWLTDEDTRNLKEI-FFNILVPGAEEAQKERQRQKELE 629
E R DE+ L+++ L G ++ K+++ Q++ E
Sbjct: 237 ERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFE 277
Score = 34.3 bits (77), Expect = 0.37
Identities = 77/352 (21%), Positives = 134/352 (38%), Gaps = 34/352 (9%)
Query: 280 GPQVWSETKSGVAPQKMAGASPTKDDSKDSDFWKMLNEPED--QAPGGEEVPAEEQDPSP 337
GP + S + A K+ + K + K+ + K E + EE+ ++D S
Sbjct: 209 GPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSK 268
Query: 338 EAADSASGAPNDFQNNVQVKVIRSPADLIRFIEELKGGTKKGKPNIGQEQPVDDA---AE 394
+ ++ V V PA E+ + T N G ++ D E
Sbjct: 269 QKESQRKFEEETVKSKVTVDTGVIPASE----EKAETPTAAEDDNEGDKKKKDKKKKKGE 324
Query: 395 VPQREPEKERGDPERQ-REMEE-----EEDEDEDEDEDEDERQLLGEFE-KELEGILLPS 447
++E EK++G + + M+E +E+E+ + E+E+ + L E E K E L
Sbjct: 325 KEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQ 384
Query: 448 DRDRLRSETEKELDPDGLKKE----SERDRAMLALTSTLNKLIKR--LEEKQSPELVKK- 500
++ + + EKE + LKKE ++ R A KL++ +E L KK
Sbjct: 385 EKRERKKQKEKE-RKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKR 443
Query: 501 ---HKKKRVVPKKPPPSPQPTEEDPEHRVRVRVTKLRLGGPNQDLTVLEMKRENPQLKQI 557
KKR KK P + E + V + G P ++ T ++ E + +
Sbjct: 444 PIYEDKKR---KKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTED 500
Query: 558 EGL----VKELLEREGLTAAGKIEIKIVRPWAEGTEEGARWLTDEDTRNLKE 605
GL E K+ I++ E EE DE++ +E
Sbjct: 501 AGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEE 552
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 48.5 bits (114), Expect = 2e-05
Identities = 59/254 (23%), Positives = 106/254 (41%), Gaps = 25/254 (9%)
Query: 231 PLLRPPPSAAPQAILCHPSLQPEEYMAYVQRQADSKQYGDKIIEELQDLGPQVWSETKSG 290
P ++P +++ + + + E Q A++KQ + ++EE + + E K
Sbjct: 32 PEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQ--EAVVEEDYNENAKN-GEAKIT 88
Query: 291 VAP-----------QKMAGASPTKDDSKDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEA 339
AP + + A+ + K++ ++ NE EDQ E+ E+ + E
Sbjct: 89 EAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKED 148
Query: 340 ADSAS--GAPNDFQNNVQVKVIRSPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEV-- 395
D D N + + + D + E+ KG + GK E+ +D E
Sbjct: 149 KDEKGEEDGKEDKNGNEKGEDAKEKEDGKKG-EDGKGNGEDGKEKGEDEKEEEDRKETGD 207
Query: 396 -PQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRS 454
+ E KE+GD + ++++ +EDE E ED EDE E KE E + ++
Sbjct: 208 GKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDL-----KEEEEG 262
Query: 455 ETEKELDPDGLKKE 468
+ E E+ D KKE
Sbjct: 263 KEEDEIKEDDGKKE 276
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 48.5 bits (114), Expect = 2e-05
Identities = 66/301 (21%), Positives = 128/301 (42%), Gaps = 33/301 (10%)
Query: 258 YVQRQADSKQYGDKIIEEL-QDLGPQVWSETKSGVAPQKMAGASPTKDDSKDSDFWKMLN 316
+V+ +A +Q DK +E+ +DL E K QK P D ++ D K L
Sbjct: 1395 HVKNEAVKQQ--DKALEQKGRDL------EQKDTALEQKDKALEPKDKDLEEKD--KAL- 1443
Query: 317 EPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIRSPADLIRFIEELKGGT 376
E +D+ P ++ E++D + E D A P D + +V+ + EE
Sbjct: 1444 EQKDKIPEEKDKALEQKDTALEQKDKAL-EPKDKDLEQKDRVLEQKE---KIPEEKDKAL 1499
Query: 377 KKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDED--EDERQLLG 434
+ ++ + P D AE+ R+ E+ PE++ + +E++D+ ++ + E + LG
Sbjct: 1500 DQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALG 1559
Query: 435 EFEKELEGILLPSDRDRLRSETE--------------KELDPDGLKKESERDRAMLALTS 480
+ ++ LE + + + E E +E P+ +K E+ A+L T
Sbjct: 1560 QKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTK 1619
Query: 481 TLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTEEDPEHRVRVRVTKLRLGGPNQ 540
L ++E ++ E +K+ + + V ++ + PT E+P + P Q
Sbjct: 1620 ALGLEESLVQEGRAREQEEKYWRGQDVVQEWQET-SPTREEPAGEQKELAPAWEDTSPEQ 1678
Query: 541 D 541
D
Sbjct: 1679 D 1679
Score = 45.1 bits (105), Expect = 2e-04
Identities = 39/182 (21%), Positives = 77/182 (42%), Gaps = 17/182 (9%)
Query: 314 MLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIRSPADLIRFIEELK 373
+L E D G + P + + P + + G P Q + + +L+ + E +
Sbjct: 545 LLAEQRDTGLGDKPFPLDTAEEGPPST-AIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQ 603
Query: 374 GGTKKG---------KPNIGQEQPVDDAAEVPQREPEKERGDPE------RQREMEEEED 418
G +G + + +E+ +A +P R +E +PE + E+EE E+
Sbjct: 604 GSKDRGLDSGAETEEEKDTWEEKKQREAERLPDRTEAREESEPEVKEDVIEKAELEEMEE 663
Query: 419 EDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLAL 478
++E+ED + G ++K ++ L + R R + +EL G E E + +L
Sbjct: 664 VHPSDEEEEDATKAEGFYQKHMQEPLKVTPRSR-EAFGGRELGLQGKAPEKETSLFLSSL 722
Query: 479 TS 480
T+
Sbjct: 723 TT 724
Score = 43.9 bits (102), Expect = 5e-04
Identities = 46/158 (29%), Positives = 69/158 (43%), Gaps = 30/158 (18%)
Query: 314 MLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIRSPADLIRFIEELK 373
+L+ PED EE+ EE+ E D+ G D + P+ I+
Sbjct: 524 VLSSPEDLTQDFEEMKREERALLAEQRDTGLG---DKPFPLDTAEEGPPSTAIQ------ 574
Query: 374 GGTKKGKPNIGQEQPV----DDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDE 429
GT P +GQE+ V + EVP+ + K+RG + E EEE+D E++ + E E
Sbjct: 575 -GTPPSVPGLGQEEHVMKEKELVPEVPEEQGSKDRG-LDSGAETEEEKDTWEEKKQREAE 632
Query: 430 RQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGLKK 467
R LP DR R E+E E+ D ++K
Sbjct: 633 R--------------LP-DRTEAREESEPEVKEDVIEK 655
Score = 30.0 bits (66), Expect = 7.0
Identities = 38/206 (18%), Positives = 87/206 (42%), Gaps = 23/206 (11%)
Query: 377 KKGKPNIGQE-QPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGE 435
K GK ++ ++ +++ + ++E +KER + ++ +EE+ + + E++ +D + L +
Sbjct: 399 KVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKK 458
Query: 436 FEKELEGILLPSDR--------------DRLRS-ETEKELDPDGLKKESERDRAMLALTS 480
K P R DR R+ EKEL + +++ L S
Sbjct: 459 ISKPDLKPFTPEVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTIS 518
Query: 481 TLNKLIKRLEEKQSPELVKKHKKKRVVPKK-------PPPSPQPTEEDPEHRVRVRVTKL 533
+L+ E + + + +++R + + P P T E+ ++ T
Sbjct: 519 GHRELVLSSPEDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPP 578
Query: 534 RLGGPNQDLTVLEMKRENPQLKQIEG 559
+ G Q+ V++ K P++ + +G
Sbjct: 579 SVPGLGQEEHVMKEKELVPEVPEEQG 604
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 47.8 bits (112), Expect = 3e-05
Identities = 65/309 (21%), Positives = 125/309 (40%), Gaps = 46/309 (14%)
Query: 260 QRQADSKQYGDKIIEELQDLGPQVWSETKSGVAPQKMAGASPTKDDSKDSDFW------- 312
+RQ K+Y ++ EELQ Q+ E + Q+ KD+ + +
Sbjct: 982 RRQEREKKYREE--EELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREERE 1039
Query: 313 -KMLNEPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIRSPADLIRFIEE 371
+ L E E Q EE+ EE+ E ++ + Q + ++ + L+R E
Sbjct: 1040 KRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPE 1099
Query: 372 LKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDED--EDEDE 429
+ ++ + +E+ + ++ + E EK R ++ EEEE + E+E +E E
Sbjct: 1100 KRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPE 1159
Query: 430 RQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLALTSTLNKLIKRL 489
++ E E++ + + L+ E E+ L + K+ ER+R
Sbjct: 1160 KRRRQELERQYR------EEEELQQEEEQLLREEQEKRRQERER---------------- 1197
Query: 490 EEKQSPELVKKHKKKRVVPKKPPPSPQPTEEDPEHRVRVRVTKLRLGGPNQDLTVLEMKR 549
+ + E +++ K+K+ + S + +PE VR K+ G R
Sbjct: 1198 -QYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKG-----------R 1245
Query: 550 ENPQLKQIE 558
EN Q +Q+E
Sbjct: 1246 ENEQFRQLE 1254
Score = 45.4 bits (106), Expect = 2e-04
Identities = 55/275 (20%), Positives = 113/275 (41%), Gaps = 25/275 (9%)
Query: 370 EELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDEDEDEDE 429
EEL+ ++ + QE+ + ++ Q E + R + E++R E E +D+ + E
Sbjct: 911 EELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKE 970
Query: 430 RQLLGEFEKEL-----------EGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLAL 478
QLLGE ++ E L + LR E EK + ++ ++D L
Sbjct: 971 EQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDE----L 1026
Query: 479 TSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTEEDPEHRVRVRVTKLRLGGP 538
+L++ EE++ L ++ ++ R + Q E+ E R R + +
Sbjct: 1027 QQEEEQLLR--EEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEE 1084
Query: 539 NQDLTVLEMKRENPQLKQIEGLVKELLEREGLTAAGKIEIKIVRPWAEGTEEGARWLTDE 598
++ RE P+ ++ + ++ E E L + ++ R E ++ +E
Sbjct: 1085 ELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEE 1144
Query: 599 DTRNLKEIFFNILVPGAEEAQKERQRQKELESNYR 633
+ + +E + E++R++ELE YR
Sbjct: 1145 EVQQEEEQLL--------REEPEKRRRQELERQYR 1171
Score = 43.9 bits (102), Expect = 5e-04
Identities = 56/255 (21%), Positives = 111/255 (43%), Gaps = 31/255 (12%)
Query: 385 QEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDE--DEDEDEDERQLLGEFEKELEG 442
+EQ + E +RE ++ER + + +RE +EE E + E E+ E+QL E E+E
Sbjct: 302 REQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERR- 360
Query: 443 ILLPSDRDRLRSETEKELDPDGLKKESERDRAMLALTSTLNKLIKRLEEKQSPELVKKHK 502
+LR E E+E L++E + R + ++L +Q ++ +
Sbjct: 361 ------EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 414
Query: 503 KKRVVPKKPPPSPQPTEEDPEHRVRVRVTKLRLGGPNQDLTVLEMKRENPQLKQIEGLVK 562
+++ + ++ + EE E + E +R +LK+ + +
Sbjct: 415 REQQLRREQQLRREQEEERHEQK-------------------HEQERREQRLKREQEERR 455
Query: 563 ELLEREGLTAAGKIEIKIVRPWAEGTEE-GARW--LTDEDTRNLKEIFFNILVPGAEEAQ 619
+ L+RE T + E + + + EE RW L +E+ R +E L EE +
Sbjct: 456 DWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERR 515
Query: 620 KERQRQKELESNYRR 634
++R +++E E ++
Sbjct: 516 EQRLKRQEEEERLQQ 530
Score = 43.9 bits (102), Expect = 5e-04
Identities = 57/233 (24%), Positives = 100/233 (42%), Gaps = 52/233 (22%)
Query: 397 QREPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSET 456
++ E+ER + +RE EE D+ +E+ +++L E E+ LE L + +RL E
Sbjct: 555 EKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEE 614
Query: 457 EKELDPDGLKKES-ERDRAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSP 515
+E LK+E E +R L S + EE++ +L ++ +++R K
Sbjct: 615 RRE---QRLKREEPEEERRQQLLKS------EEQEERRQQQLRREQQERREQRLK----- 660
Query: 516 QPTEEDPEHRVRVRVTKLRLGGPNQDLTVLEMKRENPQLKQIEGLVKELLEREGLTAAGK 575
E+ E R+ R +KRE+ + E +EL E E A +
Sbjct: 661 ---REEEEERLEQR-----------------LKREHEE----ERREQELAEEEQEQARER 696
Query: 576 IEIKIVR-PWAEGTEEGARWLTDEDTRNLKEIFFNILVPGAEEAQKERQRQKE 627
I+ +I + W +E AR +++ P +E Q+ RQ Q+E
Sbjct: 697 IKSRIPKWQWQLESEADAR---------QSKVYSR---PRKQEGQRRRQEQEE 737
Score = 42.0 bits (97), Expect = 0.002
Identities = 61/278 (21%), Positives = 119/278 (42%), Gaps = 51/278 (18%)
Query: 376 TKKGKPNIGQEQPVDD-------AAEVPQREP-----EKERGDPERQREMEEEEDEDEDE 423
+++G+ + P+ + A E QRE E+E+ RQR E+E + +E
Sbjct: 777 SERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEE 836
Query: 424 DEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGLKKESERDR------AMLA 477
+E R+ + ++E +G L D++R RS+ ++ + E ER R A A
Sbjct: 837 EEQLQRRERAQQLQEEEDG--LQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPA 894
Query: 478 LTSTLNKLIKRL-EEKQSPELVKKHKKKRVVPKKPPPSPQPTEEDPEHRVRVRVTKLRLG 536
L L K + L EE++ + ++ K++R ++ + +++ E +R K R
Sbjct: 895 LQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRR- 953
Query: 537 GPNQDLTVLEMKRENPQLKQIEGLVKELLEREGLTAAGKIEIKIVRPWAEGTEEGARWLT 596
E +R+ + K+++ ++LL E + K R E L
Sbjct: 954 --------QERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEE--------LQ 997
Query: 597 DEDTRNLKEIFFNILVPGAEEAQKERQRQKELESNYRR 634
E+ + L+E ++E++R++E E YR+
Sbjct: 998 QEEEQLLRE-------------EREKRRRQEWERQYRK 1022
Score = 40.4 bits (93), Expect = 0.005
Identities = 65/281 (23%), Positives = 117/281 (41%), Gaps = 31/281 (11%)
Query: 369 IEELKGGTKKGKPNIGQEQPVDDAA---EVPQREPEKERGDPERQREMEEEEDEDEDEDE 425
++E K GK ++ Q++ ++ E R+ E+E G RQ+ E+E + E E++
Sbjct: 95 LDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQ 154
Query: 426 DEDERQLLGEFEKELEGILLP-----SDRDRLRSETEKELDPDGLKKESERDRAMLALTS 480
E + +L + + L +R+ R+E E+ G + E D L
Sbjct: 155 SEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRE 214
Query: 481 TLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTEEDPEHRVRVRV-----TKLRL 535
L K EEKQ ++ ++ RV + EE+ E R R V KL+
Sbjct: 215 LLELRRKGREEKQQQ---RRERQDRVFQE---------EEEKEWRKRETVLRKEEEKLQE 262
Query: 536 GGPNQDLTVLEMKRENPQLKQIE--GLVKELLEREGLTAAGKIEIKIVRPW-AEGTEEGA 592
P + E++ E QL+++E L +E E E + E ++ R E E+
Sbjct: 263 EEPQRQ---RELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQE 319
Query: 593 RWLTDEDTRNLKEIFFNILVPGAEEAQKERQRQKELESNYR 633
++ R +E + +E ++E+Q ++E E R
Sbjct: 320 ERREQQERREQQEERREQQLRREQEERREQQLRREQEEERR 360
Score = 38.5 bits (88), Expect = 0.020
Identities = 64/284 (22%), Positives = 119/284 (41%), Gaps = 37/284 (13%)
Query: 385 QEQPVDDAAEVPQ--REPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEG 442
QE+ E PQ R+ +++ +R R+ EEE ++ +E + RQ +E E
Sbjct: 1639 QERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQ 1698
Query: 443 ILLPSDRDRLRSETEKELDPDGLKKE--------SERDRAMLALTSTLNKLIKRLEEKQS 494
L +R+R + E++L L+++ E ++ L K+++ EE+
Sbjct: 1699 QLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILE--EEQLR 1756
Query: 495 PELVKKHKKKRVVPKKPPPSPQPTEEDPEHRVRVRVTKLRLGGPNQDLTVLEMKRENPQL 554
PE ++ +++ +K Q +E E ++R + + + Q L +RE QL
Sbjct: 1757 PEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQ----LRQEREEQQL 1812
Query: 555 KQIEGLVKELLEREGLTAAGKIE-IKIVRPWAEGTEEGARWLTDEDTRNLKEIFFNILVP 613
+ + K E E L + + ++ R EE ++ T E +R ++ +
Sbjct: 1813 RPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEE--QFATQEKSRREEQELWQ---- 1866
Query: 614 GAEEAQKERQ------------RQKELESNYRRVWGSPGGEGTG 645
EE QK RQ RQ++ E +R+V EG G
Sbjct: 1867 --EEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKG 1908
Score = 36.6 bits (83), Expect = 0.075
Identities = 41/186 (22%), Positives = 79/186 (42%), Gaps = 12/186 (6%)
Query: 317 EPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIRSPADLIRFIEELKGGT 376
E E Q EE+ EE+ E + + Q + ++ + L+R E +
Sbjct: 1075 ELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQ 1134
Query: 377 KKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDEDE----DEDEDERQL 432
+ + +E+ + ++ + EPEK R ++ EEEE + E+E +E E RQ
Sbjct: 1135 ELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQE 1194
Query: 433 LGEFEKELEGILLPSDRDRLRSETEK-----ELDPDGLKKESERDRAMLALTSTLNKLIK 487
+E E + + R R E ++ + +P+ K+ + RD + N+ +
Sbjct: 1195 RERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPE--KENAVRDNKVYC-KGRENEQFR 1251
Query: 488 RLEEKQ 493
+LE+ Q
Sbjct: 1252 QLEDSQ 1257
Score = 35.8 bits (81), Expect = 0.13
Identities = 55/274 (20%), Positives = 113/274 (41%), Gaps = 40/274 (14%)
Query: 372 LKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDE--------DE 423
LK ++ + + +EQ + + E E+ + R++ ++ EE E+E +E
Sbjct: 579 LKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEE 638
Query: 424 DEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLALTSTLN 483
E+ ++QL E ++ E RL+ E E+E LK+E E +R L
Sbjct: 639 QEERRQQQLRREQQERRE--------QRLKREEEEERLEQRLKREHEEERREQELAEEEQ 690
Query: 484 KLIKRLEEKQSP------ELVKKHKKKRVVPKKPPPSPQPTEEDPEHRVRVRVTKLRLGG 537
+ + + + P E ++ +V + Q ++ E + R R ++L+
Sbjct: 691 EQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQW-- 748
Query: 538 PNQDLTVLEMKRENPQLKQI--EGLVKELLEREGLTAAGKIEIKIVRPWAEGTEEGARWL 595
++ ++E Q + + +E ER G+ + P E E R L
Sbjct: 749 -QEEERAHRQQQEEEQRRDFTWQWQAEEKSER------GRQRLSARPPLREQRE---RQL 798
Query: 596 TDEDTRNLKEIFFNILVPGAEEAQKERQRQKELE 629
E+ + ++ F +P EE ++ R++++E E
Sbjct: 799 RAEERQQREQRF----LPEEEEKEQRRRQRRERE 828
Score = 35.4 bits (80), Expect = 0.17
Identities = 54/282 (19%), Positives = 118/282 (41%), Gaps = 19/282 (6%)
Query: 370 EELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDEDE---DEDED 426
EE + ++ + + + ++ E R ++ER + + +RE EEE E + +++E+
Sbjct: 312 EERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEE 371
Query: 427 EDERQLLGEFEKELEGILLPSDRDRLRSETEKELD---PDGLKKESE--RDRAMLALTST 481
E+QL E + E L + R + +E L++E + R++ +
Sbjct: 372 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEE 431
Query: 482 LNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTEE--------DPEHRVRVRVTKL 533
K +E++ L ++ +++R K+ + + +E D E R R KL
Sbjct: 432 ERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKL 491
Query: 534 RLGGPNQDLTVLEMKRENPQLKQIEGLVKELLEREGLTAAGKIEIKIVRPWAEGTEEGAR 593
+ E + Q ++ E +K E E L + E ++ R E E +
Sbjct: 492 EEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRR---EQEERREQ 548
Query: 594 WLTDEDTRNLKEIFFNILVPGAEEAQKERQRQKELESNYRRV 635
L E+ + L++ + +E ++++ ++E E +R+
Sbjct: 549 LLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRL 590
Score = 35.4 bits (80), Expect = 0.17
Identities = 64/327 (19%), Positives = 137/327 (41%), Gaps = 31/327 (9%)
Query: 317 EPEDQAPGGEEVPAEEQDPSPEAADSASGAPNDFQNNVQVKVIRSPADLIRFIEELKGGT 376
E E Q E++ EE+ E + + Q K+ + L+ E +
Sbjct: 925 EQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQ 984
Query: 377 KKGKPNIGQEQPVDDAAEVPQREPEKERGDP-ERQ-REMEEEEDEDEDEDEDEDERQLLG 434
++ K +E+ + ++ + E EK R ERQ R+ +E + E+E +E E++ L
Sbjct: 985 EREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQ 1044
Query: 435 EFEKELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLALTSTLNKLIKRLEE--K 492
E E++ + + L+ E E+ L G ++E+ R + + +L + E+ +
Sbjct: 1045 ERERQYR------EEEELQQEEEQLL---GEERETRRRQELERQYRKEEELQQEEEQLLR 1095
Query: 493 QSPELVKKHKKKRVVPKK---PPPSPQPTEEDPEHRVRVRVTKLRLGGPNQDLTVLEMKR 549
+ PE ++ +++R ++ Q E+ E R R + + ++ R
Sbjct: 1096 EEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLR 1155
Query: 550 ENPQLKQIEGLVKELLEREGLTAAGKIEIKIVRPWAEGTEEGARWLTDEDTRNLKEIFFN 609
E P+ ++ + L ++ E E L + E +++R +E R + R +E+
Sbjct: 1156 EEPEKRRRQELERQYREEEELQ---QEEEQLLRE----EQEKRRQERERQYREEEEL--- 1205
Query: 610 ILVPGAEEAQKERQRQKELESNYRRVW 636
+ +K+R R ++ S+ + W
Sbjct: 1206 -----QRQKRKQRYRDEDQRSDLKWQW 1227
Score = 34.3 bits (77), Expect = 0.37
Identities = 59/231 (25%), Positives = 100/231 (43%), Gaps = 25/231 (10%)
Query: 398 REPEKERGDPERQREMEEEEDE--DEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSE 455
RE E++ ER+R+ EEE + E + +E QLL E E++ L +RDR E
Sbjct: 1433 REEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQ---LHRQERDRKFLE 1489
Query: 456 TEKELDPDGLKKESERDRAMLALTSTLNKLIKR-LEEKQSPELVKKHKKKRVVPKKPPPS 514
E++L + ERDR + ++ LEE+Q +L ++ ++++ + ++
Sbjct: 1490 EEQQL------RRQERDRKFREQELRSQEPERKFLEEEQ--QLHRQQRQRKFLQEEQQLR 1541
Query: 515 PQPTEEDPEHRVRVRVTKLRLGGPNQDLTVLEMKRENPQLKQIEGLVKELLEREGLTAAG 574
Q E + R + R K R + L +RE QL + E K LE + +
Sbjct: 1542 RQ---ERGQQRRQDRDRKFR------EEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQE 1592
Query: 575 KIEIKIVRPWAEGTEEGARWLTDEDTRNLKEIFFNILVPGAEEAQKERQRQ 625
+ + +EG + L E R +E L+ EE Q RQ +
Sbjct: 1593 QERKFMEDEQQLRRQEGQQQLRQERDRKFRE--DEQLLQEREEQQLHRQER 1641
Score = 32.3 bits (72), Expect = 1.4
Identities = 66/350 (18%), Positives = 134/350 (38%), Gaps = 80/350 (22%)
Query: 351 QNNVQVKVIRSPADLIRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQ 410
+ ++ ++ R + + E + K+ +P + Q + + E +R ++ R + + +
Sbjct: 595 EERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQER 654
Query: 411 REMEEEEDEDED--------EDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELD- 461
RE + +E+E+ E E+E Q L E E+E + S + + + E E D
Sbjct: 655 REQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADA 714
Query: 462 -----------PDGLKKESERDRAMLALTSTL------NKLIKRLEEKQSPELV------ 498
+G ++ E++ S L ++ EE+Q +
Sbjct: 715 RQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAE 774
Query: 499 -KKHKKKRVVPKKPPPSPQ------------------PTEEDPEHRVRVRVTKLRLGGPN 539
K + ++ + +PP Q P EE+ E R R R +
Sbjct: 775 EKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRER------E 828
Query: 540 QDLTVLEMKRENPQLKQIEGLVKELLEREGLTAAGKIEIKIVRPWAEGTEEGARWLTDED 599
++L LE E QL++ E + E +GL + + + R + ++ RW +E+
Sbjct: 829 KELQFLE---EEEQLQRRERAQQLQEEEDGL----QEDQERRRSQEQRRDQKWRWQLEEE 881
Query: 600 TRNLKEIFF-------------NILVPGAEEAQ---KERQRQKELESNYR 633
+ + + +L EE Q +E++R++E E YR
Sbjct: 882 RKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYR 931
Score = 32.0 bits (71), Expect = 1.8
Identities = 27/91 (29%), Positives = 52/91 (57%), Gaps = 6/91 (6%)
Query: 386 EQPVDDAAEVPQREPEKERGDPERQR-EMEEEEDEDEDEDEDEDERQLLGEFEKELEGIL 444
EQ D + +R +++R PE ++ E EE+++ + + ++E+QLL E E+E +
Sbjct: 1273 EQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLRE-EREEKRRR 1331
Query: 445 LPSDRDRLRSETE--KELDPDGLKKESERDR 473
+DR + R E + +E + L+++ ERDR
Sbjct: 1332 QETDR-KFREEEQLLQEREEQPLRRQ-ERDR 1360
Score = 31.6 bits (70), Expect = 2.4
Identities = 57/267 (21%), Positives = 109/267 (40%), Gaps = 35/267 (13%)
Query: 307 KDSDFWKMLNEPEDQAPGGEEVPAEEQDPSPEAADSASG-APNDFQNNVQVKVIRSPADL 365
+D + W+ E +++ EE AEE E S G +F + Q++
Sbjct: 169 RDEELWRQRQEWQER----EERRAEE-----EQLQSCKGHETEEFPDEEQLRR------- 212
Query: 366 IRFIEELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPE----RQREMEEEEDEDE 421
R + EL+ +KG+ Q+Q + V Q E EKE E ++ E +EE+
Sbjct: 213 -RELLELR---RKGREE-KQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQR 267
Query: 422 DEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGLKKESERDRAMLALTST 481
+ E+E QL +EL ++ + R E++L +K+ E R
Sbjct: 268 QRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQL----RRKQEEERREQQEERRE 323
Query: 482 LNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPSPQPTE-----EDPEHRVRVRVTKLRLG 536
+ ++ EE++ +L ++ +++R + + E E E R ++ + +
Sbjct: 324 QQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQL 383
Query: 537 GPNQDLTVLEMKRENPQLKQIEGLVKE 563
Q L + R QL++ + L +E
Sbjct: 384 RREQQLRREQQLRREQQLRREQQLRRE 410
Score = 30.4 bits (67), Expect = 5.3
Identities = 29/145 (20%), Positives = 64/145 (44%), Gaps = 9/145 (6%)
Query: 370 EELKGGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPERQREMEEEEDE-------DED 422
EE K ++ + + ++Q + + E +R E +R E ++ ++E E++ D
Sbjct: 1302 EEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRK 1361
Query: 423 EDEDEDERQLLGEFEKELEGILLPSDRDR--LRSETEKELDPDGLKKESERDRAMLALTS 480
E+E Q G E E L +R+R L+ E + + +RDR
Sbjct: 1362 FREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQ 1421
Query: 481 TLNKLIKRLEEKQSPELVKKHKKKR 505
L++ + + ++ + V++ +++R
Sbjct: 1422 QLSRQERDRKFREEEQQVRRQERER 1446
Score = 30.0 bits (66), Expect = 7.0
Identities = 43/184 (23%), Positives = 78/184 (42%), Gaps = 33/184 (17%)
Query: 399 EPEKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEK 458
E E+ ER+R+ +EE + ++ ++ RQ +E E L +RDR E E+
Sbjct: 1378 EEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQ 1437
Query: 459 ELDPDGLKKESERDRAMLALTSTLNKLIKR--------LEEKQSPELVKKHKKKRVVPKK 510
++ + ER+R L L + R L+E++ +L ++ + ++ +
Sbjct: 1438 QV------RRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFL--- 1488
Query: 511 PPPSPQPTEEDPEHRVRVRVTKLRLGGPNQDLTVLEMKR----ENPQLKQIEGLVKELLE 566
EE+ + R + R K R Q+L E +R E QL + + K L E
Sbjct: 1489 --------EEEQQLRRQERDRKFR----EQELRSQEPERKFLEEEQQLHRQQRQRKFLQE 1536
Query: 567 REGL 570
+ L
Sbjct: 1537 EQQL 1540
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.133 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,583,815
Number of Sequences: 37866
Number of extensions: 1785447
Number of successful extensions: 29149
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 501
Number of HSP's successfully gapped in prelim test: 740
Number of HSP's that attempted gapping in prelim test: 12886
Number of HSP's gapped (non-prelim): 6690
length of query: 652
length of database: 18,247,518
effective HSP length: 109
effective length of query: 543
effective length of database: 14,120,124
effective search space: 7667227332
effective search space used: 7667227332
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.