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Search of human proteins with 63176611
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|63176611 modulator of estrogen induced transcription isoform
a [Homo sapiens]
(1034 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|63176611 modulator of estrogen induced transcription isoform ... 2053 0.0
gi|62244004 modulator of estrogen induced transcription isoform ... 2006 0.0
gi|7661936 scaffold attachment factor B2 [Homo sapiens] 451 e-126
gi|21264343 scaffold attachment factor B [Homo sapiens] 425 e-118
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 111 3e-24
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 109 1e-23
gi|148746195 trichohyalin [Homo sapiens] 109 1e-23
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 102 1e-21
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 98 4e-20
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 97 6e-20
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 97 6e-20
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 96 1e-19
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 96 2e-19
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 94 9e-19
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 89 3e-17
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 88 5e-17
gi|134152708 arginine and glutamate rich 1 [Homo sapiens] 86 1e-16
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 86 2e-16
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 86 2e-16
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 85 4e-16
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 84 7e-16
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 84 9e-16
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 84 9e-16
gi|41281453 serine/threonine kinase 2 [Homo sapiens] 84 9e-16
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 84 9e-16
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 83 1e-15
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 83 1e-15
gi|56549694 enabled homolog isoform a [Homo sapiens] 83 2e-15
gi|39930375 enabled homolog isoform b [Homo sapiens] 83 2e-15
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 82 2e-15
>gi|63176611 modulator of estrogen induced transcription isoform a
[Homo sapiens]
Length = 1034
Score = 2053 bits (5318), Expect = 0.0
Identities = 1034/1034 (100%), Positives = 1034/1034 (100%)
Query: 1 MAAATGAVAASAASGQAEGKKITDLRVIDLKSELKRRNLDITGVKTVLISRLKQAIEEEG 60
MAAATGAVAASAASGQAEGKKITDLRVIDLKSELKRRNLDITGVKTVLISRLKQAIEEEG
Sbjct: 1 MAAATGAVAASAASGQAEGKKITDLRVIDLKSELKRRNLDITGVKTVLISRLKQAIEEEG 60
Query: 61 GDPDNIELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFIKDCELENQEAHEQDGN 120
GDPDNIELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFIKDCELENQEAHEQDGN
Sbjct: 61 GDPDNIELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFIKDCELENQEAHEQDGN 120
Query: 121 DELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQEGED 180
DELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQEGED
Sbjct: 121 DELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQEGED 180
Query: 181 DTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAED 240
DTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAED
Sbjct: 181 DTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAED 240
Query: 241 DNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMN 300
DNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMN
Sbjct: 241 DNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMN 300
Query: 301 ANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKD 360
ANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKD
Sbjct: 301 ANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKD 360
Query: 361 SKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNAR 420
SKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNAR
Sbjct: 361 SKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNAR 420
Query: 421 SPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSR 480
SPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSR
Sbjct: 421 SPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSR 480
Query: 481 SSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSESI 540
SSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSESI
Sbjct: 481 SSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSESI 540
Query: 541 KKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYR 600
KKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYR
Sbjct: 541 KKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYR 600
Query: 601 RKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERL 660
RKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERL
Sbjct: 601 RKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERL 660
Query: 661 QRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQ 720
QRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQ
Sbjct: 661 QRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQ 720
Query: 721 EKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFP 780
EKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFP
Sbjct: 721 EKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFP 780
Query: 781 ESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRE 840
ESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRE
Sbjct: 781 ESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRE 840
Query: 841 SDRREVRGERDERRTVIIHDRPDITHPRHPREAGPNPSRPTSWKSEGSMSTDKRETRVER 900
SDRREVRGERDERRTVIIHDRPDITHPRHPREAGPNPSRPTSWKSEGSMSTDKRETRVER
Sbjct: 841 SDRREVRGERDERRTVIIHDRPDITHPRHPREAGPNPSRPTSWKSEGSMSTDKRETRVER 900
Query: 901 PERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVITDRGGGSQHYPEERHVVERHGRD 960
PERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVITDRGGGSQHYPEERHVVERHGRD
Sbjct: 901 PERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVITDRGGGSQHYPEERHVVERHGRD 960
Query: 961 TSGPRKEWHGPPSQGPSYHDTRRMGDGRAGAGMITQHSSNASPINRIVQISGNSMPRGSG 1020
TSGPRKEWHGPPSQGPSYHDTRRMGDGRAGAGMITQHSSNASPINRIVQISGNSMPRGSG
Sbjct: 961 TSGPRKEWHGPPSQGPSYHDTRRMGDGRAGAGMITQHSSNASPINRIVQISGNSMPRGSG 1020
Query: 1021 SGFKPFKGGPPRRF 1034
SGFKPFKGGPPRRF
Sbjct: 1021 SGFKPFKGGPPRRF 1034
>gi|62244004 modulator of estrogen induced transcription isoform b
[Homo sapiens]
Length = 1016
Score = 2006 bits (5197), Expect = 0.0
Identities = 1016/1034 (98%), Positives = 1016/1034 (98%), Gaps = 18/1034 (1%)
Query: 1 MAAATGAVAASAASGQAEGKKITDLRVIDLKSELKRRNLDITGVKTVLISRLKQAIEEEG 60
MAAATGAVAASAASGQAEGKKITDLRVIDLKSELKRRNLDITGVKTVLISRLKQAIEEEG
Sbjct: 1 MAAATGAVAASAASGQAEGKKITDLRVIDLKSELKRRNLDITGVKTVLISRLKQAIEEEG 60
Query: 61 GDPDNIELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFIKDCELENQEAHEQDGN 120
GDPDNIELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFIKDCELENQEAHEQDGN
Sbjct: 61 GDPDNIELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFIKDCELENQEAHEQDGN 120
Query: 121 DELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQEGED 180
DELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQEGED
Sbjct: 121 DELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQEGED 180
Query: 181 DTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAED 240
DTFLTAQDGEEEENEK EGSLAEADHTAHEEMEAHTTVKEAED
Sbjct: 181 DTFLTAQDGEEEENEK------------------EGSLAEADHTAHEEMEAHTTVKEAED 222
Query: 241 DNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMN 300
DNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMN
Sbjct: 223 DNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMN 282
Query: 301 ANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKD 360
ANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKD
Sbjct: 283 ANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKD 342
Query: 361 SKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNAR 420
SKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNAR
Sbjct: 343 SKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNAR 402
Query: 421 SPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSR 480
SPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSR
Sbjct: 403 SPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSR 462
Query: 481 SSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSESI 540
SSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSESI
Sbjct: 463 SSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSESI 522
Query: 541 KKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYR 600
KKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYR
Sbjct: 523 KKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYR 582
Query: 601 RKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERL 660
RKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERL
Sbjct: 583 RKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERL 642
Query: 661 QRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQ 720
QRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQ
Sbjct: 643 QRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQ 702
Query: 721 EKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFP 780
EKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFP
Sbjct: 703 EKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFP 762
Query: 781 ESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRE 840
ESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRE
Sbjct: 763 ESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRE 822
Query: 841 SDRREVRGERDERRTVIIHDRPDITHPRHPREAGPNPSRPTSWKSEGSMSTDKRETRVER 900
SDRREVRGERDERRTVIIHDRPDITHPRHPREAGPNPSRPTSWKSEGSMSTDKRETRVER
Sbjct: 823 SDRREVRGERDERRTVIIHDRPDITHPRHPREAGPNPSRPTSWKSEGSMSTDKRETRVER 882
Query: 901 PERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVITDRGGGSQHYPEERHVVERHGRD 960
PERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVITDRGGGSQHYPEERHVVERHGRD
Sbjct: 883 PERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVITDRGGGSQHYPEERHVVERHGRD 942
Query: 961 TSGPRKEWHGPPSQGPSYHDTRRMGDGRAGAGMITQHSSNASPINRIVQISGNSMPRGSG 1020
TSGPRKEWHGPPSQGPSYHDTRRMGDGRAGAGMITQHSSNASPINRIVQISGNSMPRGSG
Sbjct: 943 TSGPRKEWHGPPSQGPSYHDTRRMGDGRAGAGMITQHSSNASPINRIVQISGNSMPRGSG 1002
Query: 1021 SGFKPFKGGPPRRF 1034
SGFKPFKGGPPRRF
Sbjct: 1003 SGFKPFKGGPPRRF 1016
>gi|7661936 scaffold attachment factor B2 [Homo sapiens]
Length = 953
Score = 451 bits (1161), Expect = e-126
Identities = 360/1034 (34%), Positives = 522/1034 (50%), Gaps = 147/1034 (14%)
Query: 5 TGAVAASAASGQAEG--KKITDLRVIDLKSELKRRNLDITGVKTVLISRLKQAIEEEGGD 62
+G AS G AE +++++LRVIDL++ELK+RNLD G K+VL+ RLK+A++EEG D
Sbjct: 11 SGPGTASLGPGVAETGTRRLSELRVIDLRAELKKRNLDTGGNKSVLMERLKKAVKEEGQD 70
Query: 63 PDNI--ELTVSTDTPNKKPTKGKGKKHEADELSG------------DASVE--------D 100
PD I EL ++ K+ KG + E E +G +AS+E D
Sbjct: 71 PDEIGIELEATSKKSAKRCVKGLKMEEEGTEDNGLEDDSRDGQEDMEASLENLQNMGMMD 130
Query: 101 DAFIKDCELENQEAHE--QDGNDELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAE 158
+ + + E+ N A + +DG D L DS F +++E L A+ + A ++ E
Sbjct: 131 MSVLDETEVANSSAPDFGEDGTDGLLDS--FCDSKEYVAAQLRQLPAQPPEHA---VDGE 185
Query: 159 GIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEK--DIAGSG-------DGTQEVS 209
G K +E+ + + D + E ENEK DI G + + E+
Sbjct: 186 GF----KNTLETSSLNFKVTPD----IEESLLEPENEKILDILGETCKSEPVKEESSELE 237
Query: 210 KPLPSEGSLAEADHTAHEEMEAHTTVKEAEDDNISVTIQAED-AITLDFDGDDLLETGKN 268
+P + S D EE + + E D + + +E A D LL K
Sbjct: 238 QPFAQDTSSVGPDRKLAEEEDLFDSAHPEEGD---LDLASESTAHAQSSKADSLLAVVKR 294
Query: 269 VKITDSEASKPKDGQDAIAQSPEKESKDYEMNANHK--DGKKEDCVKGDPVEKEARESSK 326
A +P DG+ + E + +A + + E+ + P E + E+
Sbjct: 295 -----EPAEQPGDGERTDCEPVGLEPAVEQSSAASELAEASSEELAEA-PTEAPSPEARD 348
Query: 327 KAESGDK-------EKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSS 379
E G K E K S++ + Q SS KE KD K KD+KG S SG
Sbjct: 349 SKEDGRKFDFDACNEVPPAPKESSTSEGADQKMSSFKEEKDIKPIIKDEKGRVGSGSG-- 406
Query: 380 GSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVS 439
+N+WVSGLSS T+A DLKNLF KYGKV+ AKVVTNARSPGA+CYG VTMS+S E +
Sbjct: 407 ----RNLWVSGLSSTTRATDLKNLFSKYGKVVGAKVVTNARSPGARCYGFVTMSTSDEAT 462
Query: 440 RCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASV 499
+CI+HLHRTELHG++ISVEK K +P+ K++ ++ +K ++ DR + +
Sbjct: 463 KCISHLHRTELHGRMISVEKAKNEPAGKKL----SDRKECEVKKEKLSSVDRHHSVEIKI 518
Query: 500 KKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSES-IKKSEEKKRISSKSPGHMV 558
+K + EK EKKE K + I+ +++ D G T+ S + KS S+ V
Sbjct: 519 EKTVIKKEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKS------GSRGMERTV 572
Query: 559 ILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREH 618
++D++KG+ K RSKE+ S D+K + +R +IL F+K+KEQR RE
Sbjct: 573 VMDKSKGEPVIS------VKTTSRSKERSSKSQDRKSESKEKR-DILSFDKIKEQRERER 625
Query: 619 LVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERER 678
+ ER R E RR RE ERE +R+ ER+E+ RLQRER +LE +RQ+LERER
Sbjct: 626 QRQREREIRETERRREREQRERE----QRLEAFHERKEKARLQRERLQLECQRQRLERER 681
Query: 679 MERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDD 738
MERERLERER+R+E+ERRKE ERI REREELRRQQ+QLRYEQE+R +RP D+D RRDD
Sbjct: 682 MERERLERERMRVERERRKEQERIHREREELRRQQEQLRYEQERRPG-RRPYDLD-RRDD 739
Query: 739 PYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFVG 798
YW E K+++++ R +D+ R +RF+DFDHR+RG++ +D +
Sbjct: 740 AYWPEGKRVAMEDRYR----ADFPRPDHRFHDFDHRDRGQY-------------QDHAID 782
Query: 799 QSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRESDRREVRGERDERRTVII 858
+ EG + R+ +++ D R PP R+S R G ++R +
Sbjct: 783 RREGSRPMMGDHRDG-------QHYGDDRHGHGGPPERHGRDS-RDGWGGYGSDKR--LS 832
Query: 859 HDRPDITHPRHPREAGPNPSRPTSWKS---EGSMSTDKRETRVERPERSGREVSGHSVRG 915
R PR R+ G + R ++ +G+M R + R +SG S
Sbjct: 833 EGRGLPPPPRGGRDWGEHNQRLEEHQARAWQGAMDAGAASREHARWQGGERGLSGPS--- 889
Query: 916 APPGNRSSASGYGSREGDRGVITDRGGGSQHYPEERHVVERHGRDTSGPRKEWHGP---- 971
PG+ +S RG + RGG +Q + HVV G + G + G
Sbjct: 890 -GPGHMAS----------RGGVAGRGGFAQGGHSQGHVVPGGGLEGGGVASQDRGSRVPH 938
Query: 972 --PSQGPSYHDTRR 983
P P H TRR
Sbjct: 939 PHPHPPPYPHFTRR 952
>gi|21264343 scaffold attachment factor B [Homo sapiens]
Length = 915
Score = 425 bits (1092), Expect = e-118
Identities = 337/983 (34%), Positives = 495/983 (50%), Gaps = 163/983 (16%)
Query: 2 AAATGAVAASAASGQAEGKKITDLRVIDLKSELKRRNLDITGVKTVLISRLKQAIEEEGG 61
+ A GA A S+AS + ++++DLRVIDL++EL++RN+D +G K+VL+ RLK+AIE+EGG
Sbjct: 11 SGAAGAAALSSASSETGTRRLSDLRVIDLRAELRKRNVDSSGNKSVLMERLKKAIEDEGG 70
Query: 62 DPDNIELTVSTDTPNKKPTK--GKGKKHEAD--------ELSGDASVEDDAFIKDCE--- 108
+PD IE+T NKK +K KG+K E + E SGD + + +++ +
Sbjct: 71 NPDEIEIT---SEGNKKTSKRSSKGRKPEEEGVEDNGLEENSGDGQEDVETSLENLQDID 127
Query: 109 ------LENQEAHEQDGNDELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIED 162
L+ E D ++D + +N +E++ L E K E ++ IED
Sbjct: 128 IMDISVLDEAEIDNGSVADCVEDDD--ADNLQESLSDSRELVEGEMKELPEQLQEHAIED 185
Query: 163 IEKEDIESQEIEAQEGEDDTFLTAQDGEEE----ENEK--DIAGSG-------DGTQEVS 209
KE I + + + + F Q+ EE ENEK DI G + + E+
Sbjct: 186 --KETINNLDTSSSD-----FTILQEIEEPSLEPENEKILDILGETCKSEPVKEESSELE 238
Query: 210 KPLPSEGSLAEADHTAHEEMEAHTTVKEAEDDNISVTIQAED-AITLDFDGDDLLETGKN 268
+P + S D EE + + E D + + +E A D LL K
Sbjct: 239 QPFAQDTSSVGPDRKLAEEEDLFDSAHPEEGD---LDLASESTAHAQSSKADSLLAVVKR 295
Query: 269 VKITDSEASKPKDGQDAIAQSPEKESKDYEMNANHK--DGKKEDCVKGDPVEKEARESSK 326
A +P DG+ + E + +A + + E+ + P E + E+
Sbjct: 296 -----EPAEQPGDGERTDCEPVGLEPAVEQSSAASELAEASSEELAEA-PTEAPSPEARD 349
Query: 327 KAESGDK-------EKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSS 379
E G K E K S++ + Q SS ++ D+K SK++KG +S
Sbjct: 350 SKEDGRKFDFDACNEVPPAPKESSTSEGADQKMSSPEDDSDTKRLSKEEKGRSSCG---- 405
Query: 380 GSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVS 439
+N WVSGLSS T+A DLKNLF KYGKV+ AKVVTNARSPGA+CYG VTMS++ E +
Sbjct: 406 ----RNFWVSGLSSTTRATDLKNLFSKYGKVVGAKVVTNARSPGARCYGFVTMSTAEEAT 461
Query: 440 RCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASV 499
+CI HLH+TELHG++ISVEK K +P + K+ +K S +K + SDRS+ +
Sbjct: 462 KCINHLHKTELHGKMISVEKAKNEP----VGKKTSDKRDSDGKKEKSSNSDRSTNLKRDD 517
Query: 500 KKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVI 559
K + K ++K + + +K + D+K + ++S + E+ + KS G VI
Sbjct: 518 KCDRKDDAKKGDDGSGEKSK--DQDDQKPGPSERSRATKSGSRGTERTVVMDKSKGVPVI 575
Query: 560 LDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHL 619
+T G SKE+ S D+K ++ ++ F+K+KE R
Sbjct: 576 SVKTSG-----------------SKERASKSQDRK-SASREKRSVVSFDKVKEPR----- 612
Query: 620 VRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERM 679
+ R + R RE +ERE +R++ EREERERL+ RERL +RQ+LERERM
Sbjct: 613 ----KSRDSESHSRVRERSERE----QRMQAQWEREERERLEIARERLAFQRQRLERERM 664
Query: 680 ERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDP 739
ERERLERER+ +E ERR+E ERI REREELRR QQ+LRYEQE+R +++RP D+D RRDD
Sbjct: 665 ERERLERERMHVEHERRREQERIHREREELRR-QQELRYEQERRPAVRRPYDLD-RRDDA 722
Query: 740 YWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFVGQ 799
YW E K+ +LD + SD++R Q+RF+DFDHR+RGR+P+ S + E +G+
Sbjct: 723 YWPEAKRAALDE----RYHSDFNR-QDRFHDFDHRDRGRYPDHSVDRR---EGSRSMMGE 774
Query: 800 SEG----KKARPTARREDPSFERYPKNFSDSRRNE----PPPPRNELRESDRREVRGERD 851
EG ++ R S + + SD R +E PPPPR + + RRE D
Sbjct: 775 REGQHYPERHGGPERHGRDSRDGWGGYGSDKRMSEGRGLPPPPRRDWGDHGRRE-----D 829
Query: 852 ERRTVIIHDRPDITHPRHPREAGPNPSRPTSWKSE---GSMSTDKRETRVERPERSGREV 908
+R SW+ G M D + + SG
Sbjct: 830 DR----------------------------SWQGTADGGMMDRDHKRWQGGERSMSGHSG 861
Query: 909 SGHSV-RGAPPGNRSSASGYGSR 930
GH + RG G S A G SR
Sbjct: 862 PGHMMNRGGMSGRGSFAPGGASR 884
Score = 48.9 bits (115), Expect = 2e-05
Identities = 66/243 (27%), Positives = 93/243 (38%), Gaps = 43/243 (17%)
Query: 762 SRQQNRFNDFD---HRERGRFPESSAVQSSSFERRDRFVGQSEGK-KARPTARREDPSFE 817
SR++ FD + R ES + ER R Q E + + R RE +F+
Sbjct: 596 SREKRSVVSFDKVKEPRKSRDSESHSRVRERSEREQRMQAQWEREERERLEIARERLAFQ 655
Query: 818 RYPKNFSDSRRNEPPPPRNELRESDRREVRGERDERRTVIIHDRPDITHP---RHPREAG 874
R +R E E E +R V ER + I +R ++ R+ +E
Sbjct: 656 R--------QRLERERMERERLERERMHVEHERRREQERIHREREELRRQQELRYEQERR 707
Query: 875 PNPSRPTS--------WKSEGSMSTDKR-ETRVERPERSGREVSGHSVRGAPPGNRSSAS 925
P RP W + D+R + R +R H RG P +
Sbjct: 708 PAVRRPYDLDRRDDAYWPEAKRAALDERYHSDFNRQDRF--HDFDHRDRGRYPDH----- 760
Query: 926 GYGSREGDRGVITDRGGGSQHYPEERHVVERHGRDTSGPRKEWHGPPSQGPSYHDTRRMG 985
REG R ++ +R G QHYPE ERHGRD+ R W G Y +RM
Sbjct: 761 SVDRREGSRSMMGEREG--QHYPERHGGPERHGRDS---RDGWGG-------YGSDKRMS 808
Query: 986 DGR 988
+GR
Sbjct: 809 EGR 811
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 111 bits (278), Expect = 3e-24
Identities = 140/558 (25%), Positives = 228/558 (40%), Gaps = 71/558 (12%)
Query: 462 GDPSKKEMKK-------------ENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSS- 507
GD ++ +K E D K R D+ DR + Q +KE +R +
Sbjct: 51 GDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTD 110
Query: 508 -EKSEKKESKDTKKIEGKDEKNDNGASGQTSESI-KKSEEKKRISSKSPGHMVILDQTKG 565
E+ ++E + ++ E + E G G+ ++ ++ E++R + K QT
Sbjct: 111 RERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERER-----QTDR 165
Query: 566 DHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERL 625
+ R + R R ++ +ER +++R+K+ + ++ + +R RE ER
Sbjct: 166 ERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERK 225
Query: 626 RRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLE 685
R+ R R+ ERER ++ ERE +RERER +R+R +R+R +
Sbjct: 226 RQTDRERDRQRKTEREREKQAERERASERETERDKERERER--------DRDR-DRDRRQ 276
Query: 686 RERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENK 745
+ER R Q RK R R+RE R++++Q E+E+ + KR R+ + R+ E +
Sbjct: 277 KERER--QTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETE 334
Query: 746 KLSLDTDARFGHGSDYSRQQNRFNDFD---HRERGRFPESSAVQSSSFER-RDRFVGQSE 801
+ + R++ R + D +R+ GR A + ER RDR +
Sbjct: 335 R---------DREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSARER 385
Query: 802 GKKARPTARREDPSFERYPKNFSDSRR-NEPPPPRNELRESDRREVRGERDERRTVIIHD 860
++ R R ER + D +R E R + RES+R RG E++ D
Sbjct: 386 EERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERD 445
Query: 861 RPDITHPRHPREAGPNPSR--------PTSWKSEGSMSTDKRETRVERPERSGREVSGHS 912
R T R+AG R P + +S S R TR R + S + S
Sbjct: 446 RERQT----DRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAAS 501
Query: 913 VRGAPPGNRSSASGYGSREGDRGVITDRGGGSQHYPEERHVVERHGRDTSGPRKEWHGPP 972
R P G + AS RG + R E+R R + G E P
Sbjct: 502 TR-FPWGRPAKAS--------RGRVAGRRRWEPRLGEKRGQGGEGRRPSGGFGTE--NPL 550
Query: 973 SQGPSYHDTRRM--GDGR 988
SQ PS R GDG+
Sbjct: 551 SQAPSVFPGPRYTPGDGK 568
Score = 100 bits (249), Expect = 7e-21
Identities = 131/480 (27%), Positives = 194/480 (40%), Gaps = 71/480 (14%)
Query: 490 DRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKRI 549
D S + S + +R ++ K D ++ + E+ QT + E++R
Sbjct: 25 DFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRRE 84
Query: 550 SSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEK 609
+ K D R +R R EK R ++ER D++R+K+ R++ E
Sbjct: 85 KDR---------HRKRDRHRERQRDR-EKERERQTDRER---DRQREKERNRQKERERET 131
Query: 610 MKE-----------QRLREHLVRFERLRRAMELRRRREIAERER-RERERIRIIREREER 657
+E QR RE E+ R R R+ ER R +ERER + +ER ER
Sbjct: 132 EREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRER 191
Query: 658 ERLQRERERLEIERQK---LERERMERERLERERIRI---EQERRKEAERIAREREELRR 711
ER QRE+E +R ERER E ER R E++R+++ ER RE++ R
Sbjct: 192 ER-QREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTER-EREKQAERE 249
Query: 712 QQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDF 771
+ + E++K +R RD D R K+ TD + ++ R+ R +
Sbjct: 250 RASERETERDKERERERDRDRDRDR------RQKERERQTDRKRQRRTERDRETERKRER 303
Query: 772 D-----HRERGRFPESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSDS 826
RER R E + ER+ E ++ R R+ + ER + +
Sbjct: 304 QRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREG 363
Query: 827 RRNEPPPPRNELRESDRREVRGERDERRTVIIHDRPDITHPRHPREAGPNPSRPTSWKSE 886
RR + R RE DR+ R ER+ER DR R+ R T +
Sbjct: 364 RR-QAERERERERERDRQSAR-EREERE----RDR--------DRDRQKERERQTEKDRD 409
Query: 887 GSMSTDK-RETRVERPERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVITDRGGGSQ 945
G T+K RE +R GRE RG R G RE DR TDR G Q
Sbjct: 410 GQRETEKQREREKDRESERGRE------RGR---EREKQKG---RERDRERQTDRQAGRQ 457
Score = 83.6 bits (205), Expect = 9e-16
Identities = 112/425 (26%), Positives = 173/425 (40%), Gaps = 33/425 (7%)
Query: 577 EKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRRE 636
++ R KE+ER ++ +++ RK EK + ++ H ER R + R R+
Sbjct: 53 DRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHR---ERQRDREKERERQT 109
Query: 637 IAERER-RERERIRII-REREERERLQRERERLEIERQKLERER---MERER-LERERIR 690
ER+R RE+ER R RERE +R R+R +++ ER+R ERER +RER R
Sbjct: 110 DRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQR 169
Query: 691 -IEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSL 749
E+ R+KE ER +E R++Q+ + + + +R R+ + R+ +E K+
Sbjct: 170 QTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKR--- 226
Query: 750 DTDARFGHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFER---RDRFVGQSEGKKAR 806
TD D R+ R + ER R E + ER RDR + + ++ R
Sbjct: 227 QTDRE----RDRQRKTERERE-KQAERERASERETERDKERERERDRDRDRDRRQKERER 281
Query: 807 PTARREDPSFERYPKNFSDSRRNEPPPPRNELRESDRREVRGERDERRTVIIHDRPDITH 866
T R+ ER R E R RE +R R ER +R T
Sbjct: 282 QTDRKRQRRTER-------DRETERKRERQRERERERERNRKRERERERERERERQRETE 334
Query: 867 PRHPREAGPNPSRPTSWKSEGSMSTDKRETR-VERPERSGREVSGHSVRGAPPGNRSSAS 925
+E R T E + T + R ER RE S R R
Sbjct: 335 RDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDR 394
Query: 926 GYGSREGDRGVITDRGGGSQHYPEERHVVERHGRDTSGPRKEWHGPPSQGPSYHDTRRMG 985
R+ +R T++ Q E++ E+ R++ R+ Q D R
Sbjct: 395 ---DRQKERERQTEKDRDGQRETEKQREREK-DRESERGRERGREREKQKGRERDRERQT 450
Query: 986 DGRAG 990
D +AG
Sbjct: 451 DRQAG 455
Score = 80.1 bits (196), Expect = 1e-14
Identities = 83/336 (24%), Positives = 147/336 (43%), Gaps = 50/336 (14%)
Query: 458 EKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKD 517
E +G + + ++E + + + +++ +R +T+ + +KE +R + E++E +
Sbjct: 134 EGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERER 193
Query: 518 TKKIEGK--DEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILD-------------- 561
++ E K D ++ G + + E+KR + + +
Sbjct: 194 QREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASE 253
Query: 562 -QTKGDHCRPSRRGRYEKIHGRSKEKERAS-------------LDKKRDKDYRRKEILPF 607
+T+ D R R R R KE+ER + ++KR++ R +E
Sbjct: 254 RETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQ-RERERERE 312
Query: 608 EKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIRE------REERERLQ 661
K +R RE ER R E R RE ERER+ + + + RE RE R + +
Sbjct: 313 RNRKRERERERERERERQR---ETERDRE-KERERKRKRQTEMDRERNRQTGREGRRQAE 368
Query: 662 RERERLEIERQKLERERMERERLERERIR-IEQERRKEAERIA-------REREELRRQQ 713
RERER ++ RER ERER +R+R R E+ER+ E +R RERE+ R +
Sbjct: 369 RERERERERDRQSAREREERER-DRDRDRQKERERQTEKDRDGQRETEKQREREKDRESE 427
Query: 714 QQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSL 749
+ +E+ R RD + + D + K+ +L
Sbjct: 428 RGRERGREREKQKGRERDRERQTDRQAGRQRKRSTL 463
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 109 bits (273), Expect = 1e-23
Identities = 143/621 (23%), Positives = 251/621 (40%), Gaps = 64/621 (10%)
Query: 366 KDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAK 425
KD G + + + T ++V +S ++ L K G VLS K V A S +
Sbjct: 69 KDHPGLKAKENDENCGPTTTVFVGNISEKASDMLIRQLLAKCGLVLSWKRVQGA-SGKLQ 127
Query: 426 CYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDK 485
+G R + LH ++ G+ + KV + K + DE + K
Sbjct: 128 AFGFCEYKEPESTLRALRLLHDLQI-GEKKLLVKVDA-----KTKAQLDEWKA------K 175
Query: 486 KNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEG--KDEKNDNGASGQTSESI--K 541
K S+ +++ + +E+ E++++++ IE ++ ++ A Q S+S K
Sbjct: 176 KKASNGNARPETVTNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRK 235
Query: 542 KSEEKKR-------ISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKK 594
K +EKK ++ P ++ + +R + + ++ + ++K
Sbjct: 236 KKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEK 295
Query: 595 RDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREI---AERER-RERERIRI 650
K+ R+EI EK + +R RE ER R E R RE ERER RER+R R
Sbjct: 296 GKKEKERQEI---EKERRERERERERERERREREREREREREREKEKERERERERDRDRD 352
Query: 651 IREREERER---LQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIARERE 707
+ +R+R R+R+R + +R R + +RER R E+ER +E ER RERE
Sbjct: 353 RTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERER-ERERERERER-ERERE 410
Query: 708 ELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNR 767
R ++++ E+E+ KR R+ D +D Y E +KL + + Q R
Sbjct: 411 REREREREREREREREKDKKRDREED--EEDAY--ERRKLERKLREK------EAAYQER 460
Query: 768 FNDFDHRERGRFPESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSDSR 827
+++ RER + E ERR +++ K +D +Y + + +
Sbjct: 461 LKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQK 520
Query: 828 RNEPPPPRNELRESDRREVRGERDERRTVII---HDRPDITHPRHPREAGPNPSRPTSWK 884
R E E DR+ + E +E R ++ H PD R +EA +
Sbjct: 521 RLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQE 580
Query: 885 SEGSMSTDKRETRVERPERSGREVSG-----------HSVRGAPPGNRSSASGYGSREGD 933
E ++++ + E+ E E + AP + +S + + GD
Sbjct: 581 PESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGNATPNTPGD 640
Query: 934 RG----VITDRGGGSQHYPEE 950
+I Q PEE
Sbjct: 641 ESPCGIIIPHENSPDQQQPEE 661
Score = 37.0 bits (84), Expect = 0.096
Identities = 76/379 (20%), Positives = 139/379 (36%), Gaps = 40/379 (10%)
Query: 12 AASGQAEGKKITDLRVIDLKSELKRRNLDITGVKTVLI----SRLKQAIEEEGGDPDNIE 67
A++G A + +T+ L E KRR+ I G VLI S L +E P +
Sbjct: 178 ASNGNARPETVTNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKK 237
Query: 68 LTVSTDTPNKKP----------TKGKGKKHEADELSGDASVEDDAFIKDCELENQEAHEQ 117
D + P TK E +E D + + +D +++ E+
Sbjct: 238 KEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRD---THKKLEEE 294
Query: 118 DGNDELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQE 177
G E K+ +E + E +E E +R E E + EKE +E E
Sbjct: 295 KGKKE-KERQEIEKERRERERERE----RERERREREREREREREREKEKERERERERDR 349
Query: 178 GEDDTFLTAQDGE-EEENEKDIAGSGDGTQEVSKPLPSEGSL-----AEADHTAHEEMEA 231
D T +D + E + ++D S D ++ S+ E + E E
Sbjct: 350 DRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERER 409
Query: 232 HTTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGK-NVKITDSEASKPKDGQDAIAQSP 290
+ + + + + D +D E K K+ + EA+ + ++ +
Sbjct: 410 EREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRE- 468
Query: 291 EKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQ 350
K++++YE A ++ ++ + + KEA+ + E D ++D P S
Sbjct: 469 RKKTREYEKEAEREEERRRE------MAKEAKRLKEFLEDYDDDRD----DPKYYRGSAL 518
Query: 351 AKSSSKESKDSKTSSKDDK 369
K K+ + +D K
Sbjct: 519 QKRLRDREKEMEADERDRK 537
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 109 bits (273), Expect = 1e-23
Identities = 112/459 (24%), Positives = 219/459 (47%), Gaps = 41/459 (8%)
Query: 466 KKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKD 525
++++++E + + +++ ++ + + +++E++ E+ E++ + K + +
Sbjct: 386 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQ--KHEQERR 443
Query: 526 EKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHG--RS 583
E+ + + +K+ EE +R + + DQ + RR R+ K+ R
Sbjct: 444 EQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEE------ERRERWLKLEEEERR 497
Query: 584 KEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRR----RREIAE 639
+++ER +R+++ RR++ L ++ +E+RL++ L ++LRR E RR +RE +
Sbjct: 498 EQQERREQQLRREQEERREQRLKRQE-EEERLQQRLRSEQQLRREQEERREQLLKREEEK 556
Query: 640 RERRERERIRIIREREER--ERLQRERERLEIERQKLERERMER--ERLERERI-RIEQE 694
R +ER R+ RE+EER + L+RE ER +Q+L+RE+ ER +RL+RE + R+EQE
Sbjct: 557 RLEQERREQRLKREQEERRDQLLKREEER---RQQRLKREQEERLEQRLKREEVERLEQE 613
Query: 695 RRKEAERIAREREELRRQQQQLR-YEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDA 753
R+E +R+ RE E R+QQ L+ EQE+R + R+ RR+ E ++ L+
Sbjct: 614 ERRE-QRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRL 672
Query: 754 RFGHGSDYSRQQNRFNDFD---HRERGRFP--------ESSAVQSSSFERRDRFVGQSEG 802
+ H + Q+ + + R + R P E+ A QS + R + GQ
Sbjct: 673 KREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRR 732
Query: 803 KKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRESDRREVRGERDERRTVIIHDRP 862
++ RR + + + + R+ + R + + E + ER +R + RP
Sbjct: 733 QEQEEKRRRRESELQ-WQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQR---LSARP 788
Query: 863 DITHPRHPR-EAGPNPSRPTSWKSEGSMSTDKRETRVER 900
+ R + A R + E +R R ER
Sbjct: 789 PLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRER 827
Score = 104 bits (259), Expect = 5e-22
Identities = 111/468 (23%), Positives = 211/468 (45%), Gaps = 36/468 (7%)
Query: 470 KKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKND 529
++E+ + R ++ R + + ++E E+SEK+E + + + +DE+
Sbjct: 115 QEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELW 174
Query: 530 NGASGQTSESIKKSEEKKRISSKSPGHMVILDQT---KGDHCRPSRRGRYEKIHGRSKEK 586
+++EE++ S K D+ + + R+GR EK R + +
Sbjct: 175 RQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQ 234
Query: 587 ERASLDKKRDKDYRRKEIL---PFEKMKE---QRLREHLVRFERLRRA--MELRRRREIA 638
+R ++ +K++R++E + EK++E QR RE E+LR+ ELRR R+
Sbjct: 235 DRV-FQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEE 293
Query: 639 ERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERI-RIEQERRK 697
E++++ R + +R ++E ER +++ ER E + ++ ++E ++L RE+ R EQ+ R+
Sbjct: 294 EQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRR 353
Query: 698 EAERIAREREELRRQQ------QQLRYEQEKRNSLKRPRDVDHRRDDPYWSE---NKKLS 748
E E RE ++LRR+Q QQLR EQ+ R + R+ RR+ E ++
Sbjct: 354 EQEEERRE-QQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 412
Query: 749 LDTDARFGHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFVGQSEGKKARPT 808
L + + R+Q E+ R ++ ERRD + E ++
Sbjct: 413 LRREQQLRREQQLRREQEEERHEQKHEQER--REQRLKREQEERRDWLKREEETERHEQE 470
Query: 809 ARR-------EDPSFERYPKNFSDSRRNEPPPPRNELR--ESDRREVRGERDERRTVIIH 859
R+ E+ ER+ K + RR + +LR + +RRE R +R E +
Sbjct: 471 RRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQ 530
Query: 860 DRPDITHPRHPREAGPNPSRPTSWKSEGSMSTDKRETRVERPERSGRE 907
R RE + + E + ++RE R++R + R+
Sbjct: 531 RLRSEQQLR--REQEERREQLLKREEEKRLEQERREQRLKREQEERRD 576
Score = 100 bits (248), Expect = 9e-21
Identities = 108/432 (25%), Positives = 198/432 (45%), Gaps = 55/432 (12%)
Query: 466 KKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEE--KRSSEKSEKKESKDTKKIEG 523
++E+++E EK + + ++ + + + +EE KR ++ E++ KD KK++
Sbjct: 910 EEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKD-KKLQQ 968
Query: 524 KDEK--NDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHG 581
K+E+ + + E KK E++ + + +L + + R +Y K
Sbjct: 969 KEEQLLGEEPEKRRRQEREKKYREEEELQQEEE---QLLREEREKRRRQEWERQYRKKDE 1025
Query: 582 RSKEKERASLDKK-------RDKDYRRKEILPFE------KMKEQRLREHLVR----FER 624
+E+E+ +++ R++ YR +E L E + +E R R+ L R E
Sbjct: 1026 LQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE 1085
Query: 625 LRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERL 684
L++ E R E +R R+ERER + REE E Q E + L ER+K R+ +ER+
Sbjct: 1086 LQQEEEQLLREEPEKRRRQERER----QCREEEELQQEEEQLLREEREKRRRQELERQYR 1141
Query: 685 ERERIRIEQE----------RRKEAERIAREREELRRQQQQ-LRYEQEKRNSLKRPRDVD 733
E E ++ E+E RR+E ER RE EEL+++++Q LR EQEKR ++ R+
Sbjct: 1142 EEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKR---RQERERQ 1198
Query: 734 HRRDDPYWSENKKLSL-DTDARFGHGSDYS-RQQNRFNDFDHRERGRFPESSAVQSSSFE 791
+R ++ + +K D D R + ++N D +GR E Q +
Sbjct: 1199 YREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFR-QLEDSQ 1257
Query: 792 RRDR--------FVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRESDR 843
RDR +G+ + + RR +P+ R + R + + +
Sbjct: 1258 LRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEE 1317
Query: 844 RE-VRGERDERR 854
++ +R ER+E+R
Sbjct: 1318 KQLLREEREEKR 1329
Score = 99.8 bits (247), Expect = 1e-20
Identities = 102/450 (22%), Positives = 205/450 (45%), Gaps = 40/450 (8%)
Query: 468 EMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEK 527
E ++ DE+ R + R K Q +++++ E+ EK+ K + ++EK
Sbjct: 200 ETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEK 259
Query: 528 NDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKE 587
+ E ++ E+ +++ + L + + + + +R R E+ R +E+E
Sbjct: 260 LQEEEPQRQRELQEEEEQLRKLERQE------LRRERQEEEQQQQRLRREQQLRRKQEEE 313
Query: 588 RASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERER 647
R ++R + R+E +E+R + L R + RR +LRR +E E R ++
Sbjct: 314 RREQQEERREQQERRE------QQEERREQQLRREQEERREQQLRREQE----EERREQQ 363
Query: 648 IRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIARERE 707
+R +E E RE+ R ++L E+Q +++ RE+ R ++ +E++ E+ R +
Sbjct: 364 LRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 423
Query: 708 ELRRQQQQLRYEQ---EKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQ 764
+LRR+Q++ R+EQ ++R + R+ + RRD W + ++ +T+ H + +Q
Sbjct: 424 QLRREQEEERHEQKHEQERREQRLKREQEERRD---WLKREE---ETER---HEQERRKQ 474
Query: 765 Q-NRFNDFDHRERGRFPESSAVQSSSFERRDRFVGQSEGKKARPTARREDPS-------F 816
Q R + + RER E + R + + E ++ + R+E+
Sbjct: 475 QLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRS 534
Query: 817 ERYPKNFSDSRRNEPPPPRNELR-ESDRRE--VRGERDERRTVIIHDRPDITHPRHPREA 873
E+ + + RR + E R E +RRE ++ E++ERR ++ + R RE
Sbjct: 535 EQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQ 594
Query: 874 GPN-PSRPTSWKSEGSMSTDKRETRVERPE 902
R + E ++RE R++R E
Sbjct: 595 EERLEQRLKREEVERLEQEERREQRLKREE 624
Score = 99.4 bits (246), Expect = 2e-20
Identities = 89/394 (22%), Positives = 185/394 (46%), Gaps = 31/394 (7%)
Query: 466 KKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKD 525
K+E K + +E R +++ + + + +++E+ ++ ++E + +K E +
Sbjct: 255 KEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQE--E 312
Query: 526 EKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKE 585
E+ + + + ++ +E++R +Q R R E+ R +E
Sbjct: 313 ERREQQEERREQQERREQQEERREQQLRREQEERREQQLR---REQEEERREQQLRREQE 369
Query: 586 KERASLDKKRDKDYRRKEILPFEKM--KEQRLR--EHLVRFERLRRAMELRRRREIAERE 641
+ER +R++ RR++ L E+ +EQ+LR + L R ++LRR +LRR +++ +
Sbjct: 370 EERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 429
Query: 642 RRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAER 701
ER + +ER E+ + + ER + +++ E ER E+ER +++ R ++E R+E
Sbjct: 430 EEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWL 489
Query: 702 IARE---REELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHG 758
E RE+ R++QQLR EQE+R + R + R ++L + + R
Sbjct: 490 KLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEER--RE 547
Query: 759 SDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFER 818
R++ + + + RE+ ++ ERRD+ + + E ++ + R ++ E+
Sbjct: 548 QLLKREEEKRLEQERREQ-------RLKREQEERRDQLLKREEERRQQRLKREQEERLEQ 600
Query: 819 YPKNFSDSRRNEPPPPRNELRESDRREVRGERDE 852
K R L + +RRE R +R+E
Sbjct: 601 RLKREEVER----------LEQEERREQRLKREE 624
Score = 98.2 bits (243), Expect = 4e-20
Identities = 156/808 (19%), Positives = 319/808 (39%), Gaps = 95/808 (11%)
Query: 112 QEAHEQDGNDELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIESQ 171
QE EQ E ++ ++ + EEE ++ ++ KR E E +E+E+ Q
Sbjct: 440 QERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQ 499
Query: 172 EIEAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEA 231
QE + Q+ E+ K + + + + L SE L E++
Sbjct: 500 ----QERREQQLRREQEERREQRLK----RQEEEERLQQRLRSEQQLRREQEERREQLLK 551
Query: 232 HTTVKEAEDDNISVTIQAEDAITLDFDGDDLLE-----TGKNVKITDSEASKPKDGQDAI 286
K E + ++ E + D LL+ + +K E + + ++ +
Sbjct: 552 REEEKRLEQERREQRLKREQ----EERRDQLLKREEERRQQRLKREQEERLEQRLKREEV 607
Query: 287 AQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTG 346
+ ++E ++ + + ++ + ++E R+ + E ++ + LK+
Sbjct: 608 ERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEER 667
Query: 347 ASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGK 406
+ K +E + + +++++ S W L S A K
Sbjct: 668 LEQRLKREHEEERREQELAEEEQEQARERIKSRIPK----WQWQLESEADARQSK----V 719
Query: 407 YGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSK 466
Y + + + K + E R AH + E E+ + D +
Sbjct: 720 YSRPRKQEGQRRRQEQEEKRRRRESELQWQEEER--AHRQQQE--------EEQRRDFTW 769
Query: 467 KEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKE-EKRSSEKSEKKESKDTKKIEGKD 525
+ +E E+ R S R + +A +++ E+R + E+KE + ++ E +
Sbjct: 770 QWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREK 829
Query: 526 EKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKE 585
E + E +++ E +++ + G ++ + R ++ R++ E
Sbjct: 830 ELQ----FLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQ------LE 879
Query: 586 KERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRER 645
+ER K+R K L + KEQ+L + E L+R +RRR+ ER+ RE
Sbjct: 880 EER----KRRRHTLYAKPALQEQLRKEQQLLQE--EEEELQREEREKRRRQEQERQYREE 933
Query: 646 ERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRI-----EQERRKEAE 700
E++ ++EE + L+ ERE+ RQ+ ER+ + ++L+++ ++ E+ RR+E E
Sbjct: 934 EQL----QQEEEQLLREEREKR--RRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQERE 987
Query: 701 RIAREREELRRQQQQ-LRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGS 759
+ RE EEL+++++Q LR E+EKR + R +R+ D E ++L
Sbjct: 988 KKYREEEELQQEEEQLLREEREKRRRQEWER--QYRKKDELQQEEEQL------------ 1033
Query: 760 DYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERY 819
R++ RER ++ E +Q + ++ +G+ + R R+ E
Sbjct: 1034 --LREEREKRRLQERER-QYREEEELQ----QEEEQLLGEERETRRRQELERQYRKEEEL 1086
Query: 820 PKNFSDSRRNEPPPPRNELRESDRREVRGERDERRTVIIHDRPDITHPRHPREAGPNPSR 879
+ R EP R + RE RE + E ++ R RE
Sbjct: 1087 QQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLL----------REEREKRRRQEL 1136
Query: 880 PTSWKSEGSMSTDKRETRVERPERSGRE 907
++ E + ++ + E PE+ R+
Sbjct: 1137 ERQYREEEEVQQEEEQLLREEPEKRRRQ 1164
Score = 89.4 bits (220), Expect = 2e-17
Identities = 84/397 (21%), Positives = 183/397 (46%), Gaps = 41/397 (10%)
Query: 447 RTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRS 506
R + GQ ++ + ++++++E +E+ SR D+K + + +++
Sbjct: 1541 RRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMED 1600
Query: 507 SEKSEKKESKDTKKIE--GKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTK 564
++ ++E + + E K +++ + + + + E ++ + P + Q +
Sbjct: 1601 EQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEP---QLRRQER 1657
Query: 565 GDHCRPSRRGRYEKIHGRSKEKERASLDK-KRDKDYRRKEILPFEKMKEQRLREHLVRFE 623
R R ++ + +E E L + +RD+ +R +E ++++ Q ++ E
Sbjct: 1658 EQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEE----QQLRRQERERKFLQEE 1713
Query: 624 RLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERER 683
+ R EL R+ E+ R+E E+ ++ R+ R+ L+ E+ R E E Q+L R+ +R+
Sbjct: 1714 QQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKF 1773
Query: 684 LERERIRIEQE----RRKEAERIAREREELR--RQQQQLRYEQ---------------EK 722
E E++R E+E R +E++R RE E+LR R++QQLR +Q E+
Sbjct: 1774 REEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQ 1833
Query: 723 RNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPES 782
L++ RD +R ++ + ++ K S + + R+Q RER + E
Sbjct: 1834 EQRLRQERDRQYRAEEQFATQEK--SRREEQELWQEEEQKRRQ-------ERER-KLREE 1883
Query: 783 SAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERY 819
+ E+R R VG+ + ++ + R +P ++
Sbjct: 1884 HIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEPGTHQF 1920
Score = 85.5 bits (210), Expect = 2e-16
Identities = 152/798 (19%), Positives = 312/798 (39%), Gaps = 82/798 (10%)
Query: 81 KGKGKKHEADELSGDASVEDDAFIKDCELENQEAHEQDGNDELKDSEEFGENEE--ENVH 138
K K + + ++L G+ + ++ + +E +Q+ L++ E +E
Sbjct: 962 KDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYR 1021
Query: 139 SKELLSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKDI 198
K+ L EE + E E +++ E++ E +E++ +E + GEE E +
Sbjct: 1022 KKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQ-------LLGEERETRR-- 1072
Query: 199 AGSGDGTQEVSKPLPSEGSLA-EADHTAHEEMEAHTTVKEAEDDNISVTIQAEDAITLDF 257
QE+ + E L E + EE E + +Q E+ L
Sbjct: 1073 ------RQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLRE 1126
Query: 258 DGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPV 317
+ + + + E + ++ Q + + PEK + E+ +++ ++ + +
Sbjct: 1127 EREKRRRQELERQYREEEEVQQEEEQ-LLREEPEKRRRQ-ELERQYREEEELQQEEEQLL 1184
Query: 318 EKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSG 377
+E + ++ E +E++ L++ + + S + + + + G
Sbjct: 1185 REEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKG 1244
Query: 378 SSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTE 437
+ + S L DL++L G+ + E
Sbjct: 1245 RENEQFRQLEDSQLRDRQSQQDLQHLLGEQQE----------------------RDREQE 1282
Query: 438 VSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQA 497
R QL E+ + +K+ +K +EK R ++K R +T
Sbjct: 1283 RRRWQQRDRHFPEEEQL---EREEQKEAKRRDRKSQEEKQLLREEREEKR---RRQETDR 1336
Query: 498 SVKKEEKRSSEKSE---KKESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSP 554
++EE+ E+ E +++ +D K E + + G E + +E++R K
Sbjct: 1337 KFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEE 1396
Query: 555 GHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQR 614
+ Q + R R ++ + + +ER ++ ++ RR+E +EQ+
Sbjct: 1397 QQLRC--QEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQ 1454
Query: 615 LREHLVRFERLRRAMELRRRREIAERERRERERIRII-------REREERERLQR----- 662
LR+ R + R +L + RE + R+ER+R + +ER+ + R Q
Sbjct: 1455 LRQE--RHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQE 1512
Query: 663 -ERERLEIERQKLERERMERERLERE----RIRIEQERRKEAERIAREREELRRQQQQLR 717
ER+ LE E Q+L R++ +R+ L+ E R Q+RR++ +R RE E+LR+++++ +
Sbjct: 1513 PERKFLE-EEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQ 1571
Query: 718 YEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERG 777
+++R+ R + RR + E K + + R G RQ+ D RE
Sbjct: 1572 LSRQERDRKFRLEEQKVRRQE---QERKFMEDEQQLRRQEGQQQLRQE---RDRKFREDE 1625
Query: 778 RFPESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNE 837
+ + Q + RDR + E + R RE + F + + +
Sbjct: 1626 QLLQEREEQQLHRQERDRKFLEEEPQLRR--QEREQQLRHDRDRKFREEEQLLQEGEEQQ 1683
Query: 838 LRESDR-REVRGERDERR 854
LR +R R+ R E + R
Sbjct: 1684 LRRQERDRKFREEEQQLR 1701
Score = 84.0 bits (206), Expect = 7e-16
Identities = 100/481 (20%), Positives = 203/481 (42%), Gaps = 47/481 (9%)
Query: 466 KKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKK---EEKRSSEKSEK---KESKDTK 519
+++ K +E+ R ++K + Q +K EE+ E+ E+ ++ +D K
Sbjct: 1427 ERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRK 1486
Query: 520 KIEGKDE--KNDNGASGQTSESIKKSEEKKRISSKSPGH------------MVILDQTKG 565
+E + + + + + E + E+K + + H + Q +G
Sbjct: 1487 FLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERG 1546
Query: 566 DHCRPSRRGRYEKIHGRSKEKERASLDKK-RDKDYRRKEILPFEKMKEQRLREHLVRFER 624
R R ++ + +E+E L ++ RD+ +R +E + +E++ E + R
Sbjct: 1547 QQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRR 1606
Query: 625 LRRAMELRRRREIAERERRERERIRIIREREERE--RLQRERERLEIERQKLERERMERE 682
+LR+ ER+R+ RE ++++EREE++ R +R+R+ LE E Q +ER ++
Sbjct: 1607 QEGQQQLRQ-----ERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQL 1661
Query: 683 RLERER-IRIEQERRKEAERIAREREE----LRRQQQQLRYEQEKRNSLKRPRDVDHRRD 737
R +R+R R E++ +E E R+E R ++QQLR ++ +R L+ + + +
Sbjct: 1662 RHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQEL 1721
Query: 738 DPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFV 797
+ + E ++L +T+ + R+Q R+ E+ R PE Q ER +F
Sbjct: 1722 ERKFREEEQLRQETE------QEQLRRQERYRKILEEEQLR-PEREEQQLRRQERDRKFR 1774
Query: 798 GQSEGKKARPTARREDPSFERYPKNFSDSRRNEP-----PPPRNELRESDRREVRGERDE 852
+ + ++ R + +R + R+ P R+ + +++ E E
Sbjct: 1775 EEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQE 1834
Query: 853 RRTVIIHDRPDITHPRHPREAGPNPSRPTSWKSEGSMSTDKRE--TRVERPERSGREVSG 910
+R DR + + W+ E +RE R E R +E
Sbjct: 1835 QRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQR 1894
Query: 911 H 911
H
Sbjct: 1895 H 1895
Score = 82.0 bits (201), Expect = 3e-15
Identities = 100/466 (21%), Positives = 201/466 (43%), Gaps = 60/466 (12%)
Query: 447 RTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRS 506
R EL Q E+++ + ++ +++E +++ R ++ + K + + E++RS
Sbjct: 1163 RQELERQYREEEELQQE-EEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRS 1221
Query: 507 SEKSEKKESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGD 566
K + + K+ + K G + ++ S+ + R S + H++ Q
Sbjct: 1222 DLKWQWEPEKENAVRDNK--VYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQE--- 1276
Query: 567 HCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFER-- 624
R +E+ER ++RD+ + +E L E+ KE + R+ + E+
Sbjct: 1277 ---------------RDREQERRRW-QQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQL 1320
Query: 625 LRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERL 684
LR E +RRR+ +R+ RE E++ ++EREE+ ++ER+R + ++L + R+ L
Sbjct: 1321 LREEREEKRRRQETDRKFREEEQL--LQEREEQPLRRQERDR-KFREEELRHQEQGRKFL 1377
Query: 685 ERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSEN 744
E E ++ RR+E ER + +++QQLR QE+ L++ RD R ++ S
Sbjct: 1378 EEE----QRLRRQERER------KFLKEEQQLRC-QEREQQLRQDRDRKFREEEQQLSRQ 1426
Query: 745 KKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFVGQSEGKK 804
++ D +F R+Q R F E+ E + F ++ + + E ++
Sbjct: 1427 ER-----DRKFREEEQQVRRQERERKFLEEEQQLRQE----RHRKFREEEQLLQEREEQQ 1477
Query: 805 ARPTAR-----REDPSFERYPKN--FSDSRRNEPPPPRNELRESDRREVRGERDERRTVI 857
R E+ R ++ F + P R L E E + R +R+
Sbjct: 1478 LHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEE----EQQLHRQQRQRKF 1533
Query: 858 IHDRPDITHPRHPREAGPNPSRPTSWKSEGSMSTDKRETRVERPER 903
+ + + R R R ++ E + ++ E ++ R ER
Sbjct: 1534 LQEEQQLR--RQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQER 1577
Score = 60.5 bits (145), Expect = 8e-09
Identities = 65/296 (21%), Positives = 124/296 (41%), Gaps = 29/296 (9%)
Query: 587 ERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERE 646
+ LD+++ KE L ++ +E+ R R +L RRR++ E+ER E
Sbjct: 91 QATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAE 150
Query: 647 RIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRI------------EQE 694
++E E+ R+R E+ RQ+ E + E R E E+++ EQ
Sbjct: 151 GEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQL 210
Query: 695 RRKEAERIAR----EREELRRQQQQLRYEQE------KRNSLKRPRDVDHRRDDP----- 739
RR+E + R E+++ RR++Q +++E KR ++ R + + ++P
Sbjct: 211 RRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRE 270
Query: 740 -YWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFVG 798
E + L+ + +QQ R R + E Q E+++R
Sbjct: 271 LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQER-RE 329
Query: 799 QSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRESDRREVRGERDERR 854
Q E ++ + R ++ E+ + + R E R + E +++R E+ RR
Sbjct: 330 QQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRR 385
Score = 36.2 bits (82), Expect = 0.16
Identities = 31/148 (20%), Positives = 66/148 (44%), Gaps = 7/148 (4%)
Query: 105 KDCELENQEAHEQDGNDELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIE 164
K E E +E + +E +D + + EEE ++ L E+ +R + ++ E +E +E
Sbjct: 556 KRLEQERREQRLKREQEERRD--QLLKREEER--RQQRLKREQEERLEQRLKREEVERLE 611
Query: 165 KEDIESQEIEAQEGEDD---TFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEA 221
+E+ Q ++ +E E++ L +++ EE ++ + ++ K E L +
Sbjct: 612 QEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQR 671
Query: 222 DHTAHEEMEAHTTVKEAEDDNISVTIQA 249
HEE + E E + I++
Sbjct: 672 LKREHEEERREQELAEEEQEQARERIKS 699
Score = 33.5 bits (75), Expect = 1.1
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 7/79 (8%)
Query: 108 ELENQEAH-EQDGNDELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKE 166
+LE QE Q+ + + + E+F E+ +EL EE KR E E I ++
Sbjct: 1829 QLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQ 1888
Query: 167 DIESQ------EIEAQEGE 179
E Q EI++QEG+
Sbjct: 1889 QKEEQRHRQVGEIKSQEGK 1907
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 102 bits (255), Expect = 1e-21
Identities = 88/493 (17%), Positives = 193/493 (39%), Gaps = 16/493 (3%)
Query: 64 DNIELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFIKDCELENQEAHEQDGNDEL 123
D+ + + S+D+ + +K K E+D D+ + +N ++ + +
Sbjct: 606 DSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNS 665
Query: 124 KDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQEGE---D 180
DS + ++ + + S S++ + + +E + + D +S + D
Sbjct: 666 SDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSD 725
Query: 181 DTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAED 240
+ D + N D + S D + S+ S + + + ++ + ++
Sbjct: 726 SDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 785
Query: 241 DNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMN 300
++ S + + D+ D + ++ + +DS++S D ++ S S D +
Sbjct: 786 NDSSNSSDSSDSSNSS-DSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDS 844
Query: 301 ANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEK--DTLKKGPSSTGASGQAKSSSKES 358
++ DG D ++ SS ++S D D+ S+ ++ S S S
Sbjct: 845 SDSSDGSDSDSSN----RSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNS 900
Query: 359 KDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTN 418
DS +S + +S +S SS SS S S N+ ++D N S+ +
Sbjct: 901 SDSDSSDSSNSSDSSDSSNSSDSSES----SNSSDNSNSSDSSNSSDSSDSSDSSNSSDS 956
Query: 419 ARSPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSS 478
+ S + + S+S++ S ++ S + D S ++ + S
Sbjct: 957 SNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSD--SSDSSNSSDSSDSSDSSD 1014
Query: 479 SRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSE 538
S +S D N+SD S+ + +S + SS+ S+ +S D+ + +D+ S +S+
Sbjct: 1015 SSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD 1074
Query: 539 SIKKSEEKKRISS 551
S S+ + S
Sbjct: 1075 SSDSSDSSESSDS 1087
Score = 87.8 bits (216), Expect = 5e-17
Identities = 107/509 (21%), Positives = 191/509 (37%), Gaps = 52/509 (10%)
Query: 82 GKGKKHEADELSGDASVEDDAFIKDCELENQEAHEQDGNDELKDSEEFGENEEENVHSKE 141
G G + DE SGD E+ KD ++ QD E G+N + SKE
Sbjct: 248 GNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSD----SKE 303
Query: 142 LLSAEENKRAHELIEAEGIEDIEK------EDIESQEIE-------AQEGEDDTFLTAQD 188
E + H ++ + E+ ED SQ IE + + +T +
Sbjct: 304 YYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKES 363
Query: 189 -----GEEEENEKDIAGSGDGTQEVSKPL--PSEGSLAEADH----------TAHEEMEA 231
G+ ++ +I G G + ++K + +EG + H T E +
Sbjct: 364 ETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNI 423
Query: 232 HTTVKEAEDDN-ISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSP 290
+++E N + + D+ + +D D K+++ D +S +G D
Sbjct: 424 EGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDF--DDKSMQGDDPNSSDESNGNDDANSES 481
Query: 291 EKESK-----DYEMNANHKDGKKEDCVKGDPVEKEARESSKKAES---GDKEKDTLKKGP 342
+ S Y + + +G D + + ++ + ++S G+ D K
Sbjct: 482 DNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSD 541
Query: 343 SSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKN 402
S G S + S S +S +S SS D S SS S SS S + S SS++ ++D N
Sbjct: 542 SGKGKSDSSDSDSSDSSNSSDSS-DSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSN 600
Query: 403 LFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKG 462
S+ ++ S +K + S S++ +++ S
Sbjct: 601 SSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSD------SKSDSSDSNSSDSSDNS 654
Query: 463 DPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIE 522
D S + + S S S D ++SD S+ + +S + SSE S+ +S D+ +
Sbjct: 655 DSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSD 714
Query: 523 GKDEKNDNGASGQTSESIKKSEEKKRISS 551
D N N + +S S S+ S
Sbjct: 715 SSDSSNSNSSDSDSSNSSDSSDSSNSSDS 743
Score = 87.8 bits (216), Expect = 5e-17
Identities = 86/496 (17%), Positives = 189/496 (38%), Gaps = 27/496 (5%)
Query: 57 EEEGGDPDNIELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFIKDCELENQEAHE 116
+ + D + + S+D+ + + + +D S D+S ++ ++ + +
Sbjct: 709 DSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSD--SSDSSDSSNSSDSSDSSDSSNSSD 766
Query: 117 QDGNDELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQ 176
+ + DS + + + N S S++ + + ++ + + D +S
Sbjct: 767 SSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDS 826
Query: 177 EGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVK 236
D+ D + D + S DG+ S + +++ ++ + ++
Sbjct: 827 SNSSDS----SDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDS 882
Query: 237 EAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDS----EASKPKDGQDAIAQSPEK 292
+++ + + ++ + + D D D + + ++S E+S D ++ S
Sbjct: 883 SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSS 942
Query: 293 ESKDYEMNANHKDGKK--EDCVKGDPVEKEARESSKKAESGDKE--KDTLKKGPSSTGAS 348
+S D ++N D + D + + +SS + S D D+ SS ++
Sbjct: 943 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSN 1002
Query: 349 GQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYG 408
S S +S DS SS S SS S S S+ + S S ++ ++D N
Sbjct: 1003 SSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1062
Query: 409 KVLSAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKE 468
S+ ++ S + S S+E S + ++ S D S
Sbjct: 1063 SSDSSDSSDSSDSSDS--------SDSSESSDSSDSSNSSDS-----SDSSDSSDSSDSS 1109
Query: 469 MKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKN 528
++ + S S +S D ++SD S + +S + SSE S+ +S D+ + +
Sbjct: 1110 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSS 1169
Query: 529 DNGASGQTSESIKKSE 544
D+ S +S S S+
Sbjct: 1170 DSSDSSDSSNSSDSSD 1185
Score = 86.3 bits (212), Expect = 1e-16
Identities = 97/528 (18%), Positives = 198/528 (37%), Gaps = 41/528 (7%)
Query: 54 QAIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFIKDCELENQE 113
+ IE +G N +T N+ GK K + + G +V+ + + E Q+
Sbjct: 374 KGIEIKGPSSGNRNITKEVGKGNE----GKEDKGQHGMILGKGNVKTQGEVVNIEGPGQK 429
Query: 114 AHE----------QDGNDELKDSEEFGE--------NEEENVHSKELLSAEENKRAHELI 155
+ D N + DS +F + N + + + ++E + +
Sbjct: 430 SEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRG 489
Query: 156 EAEGIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSE 215
+A D K++ + + E +DD+ T+ + N G+ D + S S+
Sbjct: 490 DASYNSDESKDNGNGSDSKGAE-DDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSD 548
Query: 216 GSLAEADHTAHEEMEAHTTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDS- 274
S +++ +++ + ++ ++ D N S + D+ + D D ++ + +DS
Sbjct: 549 SSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSS 608
Query: 275 ---EASKPKDGQDAIAQSP--EKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAE 329
++S D D+ + S E +S D + ++ D D + S+
Sbjct: 609 DSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDS 668
Query: 330 SGDKEKDTLKKGPSSTGASGQAKSS----SKESKDSKTSSKDDKGSTSSTSGSSGSSTKN 385
S + S+ +S + SS S ES DS SS D +S +S S+ S + +
Sbjct: 669 SDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDS 728
Query: 386 IWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHL 445
S S ++ ++D + S+ ++ S + S S++ S
Sbjct: 729 SNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDS--------SDSSDSSDSSDSS 780
Query: 446 HRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKR 505
+ ++ + S + S + SS S D N+SD S+ + +S
Sbjct: 781 NSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSD 840
Query: 506 SSEKSEKKESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKS 553
SS+ S+ + D+ D N + +S + S S++S
Sbjct: 841 SSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNES 888
Score = 83.2 bits (204), Expect = 1e-15
Identities = 86/516 (16%), Positives = 191/516 (37%), Gaps = 24/516 (4%)
Query: 57 EEEGGDPDNIELTVSTDTPNKKPTKGKGKKHEADELSGDASVED--DAFIKDCELENQEA 114
+ + D D+ + + S+D+ + + +D S D+ D D+ D + +
Sbjct: 546 KSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSS 605
Query: 115 HEQDGNDELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIESQEIE 174
D +D S+ + + + ++ + + ++ ++ + D +
Sbjct: 606 DSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNS 665
Query: 175 AQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGS------LAEADHTAHEE 228
+ + + + N D + S D + S+ S +++ ++ +
Sbjct: 666 SDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSD 725
Query: 229 MEAHTTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDS-------EASKPKD 281
++ + ++ N S + + D+ D D ++ + +DS ++S D
Sbjct: 726 SDSSNSSDSSDSSNSSDSSDSSDSSNSS-DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 784
Query: 282 GQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEK--DTLK 339
D+ S +S + ++N D + D + +SS ++S D D+
Sbjct: 785 SNDSSNSSDSSDSSNSSDSSNSSDSS-DSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSD 843
Query: 340 KGPSSTGASGQA--KSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKA 397
SS G+ + +S S S DS SS D S+ S+ S + + N S SSN+
Sbjct: 844 SSDSSDGSDSDSSNRSDSSNSSDSSDSS-DSSNSSDSSDSSDSNESSNSSDSSDSSNSSD 902
Query: 398 ADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISV 457
+D + S+ ++ S + + SS++ S + + S
Sbjct: 903 SDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSN--SS 960
Query: 458 EKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKD 517
+ S ++ + S+S S D ++SD S + +S + SS+ S+ S D
Sbjct: 961 DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSD 1020
Query: 518 TKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKS 553
+ +D+ S +S+S S+ S +
Sbjct: 1021 SSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSN 1056
Score = 62.4 bits (150), Expect = 2e-09
Identities = 52/338 (15%), Positives = 123/338 (36%), Gaps = 3/338 (0%)
Query: 62 DPDNIELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFIKDCELENQEAHEQDGND 121
D D+ + + S+D+ + + + + + S + + + D + + + +D
Sbjct: 902 DSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSD 961
Query: 122 ELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQEGEDD 181
S+ N ++ S + ++ + + ++ + S ++ D
Sbjct: 962 SSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDS 1021
Query: 182 TFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAEDD 241
+ + D + D + S D + S+ S + + + ++ + ++
Sbjct: 1022 S--NSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1079
Query: 242 NISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMNA 301
+ S + + D+ D + + S++S D ++ S +S D ++
Sbjct: 1080 DSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1139
Query: 302 NHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDS 361
N D ++ +SS ++S D D+ SS + S S +S DS
Sbjct: 1140 NSSDSSDSSESSDSSDSSDSSDSSDSSDSSD-SSDSSDSSNSSDSSDSSDSSDSSDSSDS 1198
Query: 362 KTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAAD 399
SS S SS S S S+ + S S + +++D
Sbjct: 1199 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSD 1236
Score = 60.1 bits (144), Expect = 1e-08
Identities = 56/344 (16%), Positives = 131/344 (38%), Gaps = 23/344 (6%)
Query: 58 EEGGDPDNIELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFIKDCELENQEAHEQ 117
+ D+ + + S+D+ + + ++ + S ++ D + D + +
Sbjct: 978 DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS 1037
Query: 118 DGNDELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQE 177
D +D S+ ++ N S + + ++ + + ++ D + S + +
Sbjct: 1038 DSSDSSDSSDSSDSSDSSN--SSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSD 1095
Query: 178 GEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKE 237
D + D + + D + S D + + S+ S + + ++ + +
Sbjct: 1096 SSDSS-----DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSES 1150
Query: 238 AEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDS-EASKPKDGQDAIAQSPEKESKD 296
++ + S + + D+ D D ++ + +DS ++S D D+ S +S D
Sbjct: 1151 SDSSDSSDSSDSSDSS----DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSD 1206
Query: 297 YEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSK 356
+++ D ++ ESS ++S D SS ++ S S
Sbjct: 1207 SSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSD----------SSDSSNSSDSSDSS 1256
Query: 357 ESKDSKTSSKDDKGSTS-STSGSSGSSTKNIWVSGLSSNTKAAD 399
+S DS + S D+ S S S +G++ S + G SN +D
Sbjct: 1257 DSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSD 1300
Score = 43.5 bits (101), Expect = 0.001
Identities = 96/547 (17%), Positives = 186/547 (34%), Gaps = 99/547 (18%)
Query: 81 KGKGKKHEADELSGDASVEDDAFIKDCELENQEAHEQDGNDELKDSEEFGENEEENVHSK 140
KG+G + E+ G + F L N+E + + N + +E +G + +H K
Sbjct: 77 KGEGNGSKWAEVGGKS------FSTYSTLANEEGNIEGWNGDTGKAETYGH---DGIHGK 127
Query: 141 ELLSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKD-IA 199
E E I A GI+ ++ + T + +G ++N ++
Sbjct: 128 E-----------ENITANGIQG---------QVSIIDNAGATNRSNTNGNTDKNTQNGDV 167
Query: 200 GSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAEDDNISVTIQAEDAITLDFDG 259
G ++V+ +A ++++ E E E + +T Q +
Sbjct: 168 GDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEA 227
Query: 260 DDLLETGKNVKITDSEAS--------------------KPKDGQDAIAQSPEKESKDYEM 299
+ TG++ + +S+ S + +G+D+ S +E +D+
Sbjct: 228 EVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGK 287
Query: 300 NANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESK 359
+H ++ + + E +E GDK + + +G + +
Sbjct: 288 EDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKL 347
Query: 360 DSKTSSKDDKGST--SSTSGSSGSSTKNIWVSGLSSNT--------KAADLKNLFGKYGK 409
+ + S + + T S T S K I + G SS K + K G++G
Sbjct: 348 NHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGM 407
Query: 410 VL------SAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGD 463
+L + V N PG K +E + H + G
Sbjct: 408 ILGKGNVKTQGEVVNIEGPGQK----------SEPGNKVGHSN--------------TGS 443
Query: 464 PSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEG 523
S + D S GD N+SD S+ + + + SS + + + D E
Sbjct: 444 DSNSDGYDSYDFDDKS-MQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSD----ES 498
Query: 524 KDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRS 583
KD N + + G + + + S G+ D K D S +G+ + S
Sbjct: 499 KDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSD----SGKGKSDSSDSDS 554
Query: 584 KEKERAS 590
+ +S
Sbjct: 555 SDSSNSS 561
Score = 40.8 bits (94), Expect = 0.007
Identities = 60/264 (22%), Positives = 107/264 (40%), Gaps = 24/264 (9%)
Query: 346 GASGQAKSSSKESKDSKTSSKDDKGST--SSTSGSSGSSTKNIWVSGLSSNTKAA----D 399
G G+ ++ + + S D+ G+T S+T+G++ +T+N V N A D
Sbjct: 123 GIHGKEENITANGIQGQVSIIDNAGATNRSNTNGNTDKNTQNGDVGDAGHNEDVAVVQED 182
Query: 400 LKNLFGKYGKVLSA-KVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVE 458
+ G + +++ N+ I +S A + T G+ ++
Sbjct: 183 GPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEV--TPGTGEDAGLD 240
Query: 459 KVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVK----KEEKRSSEKSEKKE 514
G PS ++ DE S + N D S+ ++ KE+ S + +
Sbjct: 241 NSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSD 300
Query: 515 SKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRG 574
SK+ EGK++ ++ +TS KSEE + G I D K +H R S+R
Sbjct: 301 SKEYYDPEGKEDPHNEVDGDKTS----KSEENSAGIPEDNGSQRIEDTQKLNH-RESKR- 354
Query: 575 RYEKIHGR-SKEKERASLDKKRDK 597
+ R +KE E ++ K +DK
Sbjct: 355 ----VENRITKESETHAVGKSQDK 374
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 98.2 bits (243), Expect = 4e-20
Identities = 71/267 (26%), Positives = 129/267 (48%), Gaps = 39/267 (14%)
Query: 448 TELHGQLIS---VEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEK 504
TEL Q++S + K P + +E + + +R G K+ S+R K+E+
Sbjct: 15 TEL--QMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESER---------KKER 63
Query: 505 RSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTK 564
R EK +++ K+ K+ GK EK G+ + ++ ++++R G
Sbjct: 64 REREKRKREREKERKRERGKKEKK-----GERKKEERERKKRRREKENKEGE-------- 110
Query: 565 GDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFER 624
EK + KEK+ K K+ RKE E+ KE+ ++ ER
Sbjct: 111 ------------EKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKER 158
Query: 625 LRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERL 684
R+ + R R+++ E+E +E+ R R++ ER R +R++ER ER++ ++ER ++E
Sbjct: 159 ERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEER 218
Query: 685 ERERIRIEQERRKEAERIAREREELRR 711
++ER + Q +E ER RER+E ++
Sbjct: 219 KKERQKDRQTNWREKERGKRERKERKK 245
Score = 82.8 bits (203), Expect = 2e-15
Identities = 59/209 (28%), Positives = 111/209 (53%), Gaps = 8/209 (3%)
Query: 574 GRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRR 633
G +I R +E E KK + R+KE EK K +R +E + ER ++ + R
Sbjct: 33 GWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKER--KRERGKKEKKGER 90
Query: 634 RREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLE--RERIRI 691
++E ER++R RE+ E +E+ + + ++ER ++ ERER E + E +ER R
Sbjct: 91 KKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERK 150
Query: 692 EQERRKEAERIAREREELRR--QQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSL 749
++ER KE ER R++ E ++ ++++ R E+E++ KR R+ R+ + E ++
Sbjct: 151 KEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKK 210
Query: 750 DTDARFGHGSDYSRQQNRFNDFDHRERGR 778
+ + + RQ++R ++ +ERG+
Sbjct: 211 ERKKKEERKKE--RQKDRQTNWREKERGK 237
Score = 68.2 bits (165), Expect = 4e-11
Identities = 59/213 (27%), Positives = 111/213 (52%), Gaps = 15/213 (7%)
Query: 613 QRLREHLVRFERLRRAMELRRRREIAERERR----ERERIRIIREREERERLQRERERLE 668
+R RE R E ++ E R++E ERE+R E+ER RER ++E+ + ER++ E
Sbjct: 40 EREREIETRKEG-KKERESERKKERREREKRKREREKER---KRERGKKEK-KGERKKEE 94
Query: 669 IERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKR 728
ER+K RE+ +E E+E+ + ++ +KE R ++E +E R++++ R E+++R K
Sbjct: 95 RERKKRRREKENKEGEEKEKRK--KKEKKERGRTSKEGKERERKEERKREERKERERKKE 152
Query: 729 PRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPESSAVQSS 788
R+ + R + E K++ + R + R++ + + + +ER + E +
Sbjct: 153 EREKERERKERKKRERKQVGEKEEER----KEKERKERKKRERNRKERKKERERKERRER 208
Query: 789 SFERRDRFVGQSEGKKARPTARREDPSFERYPK 821
ER+ + + E +K R T RE +R K
Sbjct: 209 KKERKKKEERKKERQKDRQTNWREKERGKRERK 241
Score = 65.9 bits (159), Expect = 2e-10
Identities = 64/225 (28%), Positives = 114/225 (50%), Gaps = 28/225 (12%)
Query: 633 RRREIAERE--RRERERIRIIREREERERLQRERERLEIERQKLERERM-ERERLERERI 689
R REI R+ ++ERE R +ER ERE+ +RERE+ E +R++ ++E+ ER++ ERER
Sbjct: 41 REREIETRKEGKKERESERK-KERREREKRKREREK-ERKRERGKKEKKGERKKEERER- 97
Query: 690 RIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSL 749
++RR+E E E +E R+++++ + + +R R + +R++ E KK
Sbjct: 98 ---KKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
Query: 750 DTDARFGHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFVGQSEGKKARPTA 809
+ + R+Q + + +E+ R ER+ R + E KK R
Sbjct: 155 EKERERKERKKRERKQVGEKEEERKEKER-----------KERKKRERNRKERKKERERK 203
Query: 810 RREDPSFERYPKNFSDSRRNEPPPPRNELRESDRRE-VRGERDER 853
R + ER K + R+ E R + R+++ RE RG+R+ +
Sbjct: 204 ERRERKKERKKK---EERKKE----RQKDRQTNWREKERGKRERK 241
Score = 57.4 bits (137), Expect = 7e-08
Identities = 58/246 (23%), Positives = 105/246 (42%), Gaps = 42/246 (17%)
Query: 652 REREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRR 711
RERE R + ++ER E ER+K ER ERE+ +RER E+ER++E + ++ E
Sbjct: 41 REREIETRKEGKKER-ESERKK---ERREREKRKRER---EKERKRERGKKEKKGER--- 90
Query: 712 QQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDF 771
++E+R KR R+ +++ + KK + G + R++ R +
Sbjct: 91 -------KKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKRE- 142
Query: 772 DHRERGRFPESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEP 831
ER++R + E +K R R+E ER + R E
Sbjct: 143 -------------------ERKERERKKEEREKER--ERKERKKRERKQVGEKEEERKEK 181
Query: 832 PPPRNELRESDRREVRGERDERRTVIIHDRPDITHPRHPREAGPNPSRPTSWKSEGSMST 891
+ RE +R+E + ER+ + +R + R+ R T+W+ +
Sbjct: 182 ERKERKKRERNRKERKKERERKER---RERKKERKKKEERKKERQKDRQTNWREKERGKR 238
Query: 892 DKRETR 897
+++E +
Sbjct: 239 ERKERK 244
Score = 41.2 bits (95), Expect = 0.005
Identities = 21/102 (20%), Positives = 46/102 (45%)
Query: 447 RTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRS 506
RT G+ ++ + +KE +++ +E+ R ++K + + +KE++R
Sbjct: 125 RTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERK 184
Query: 507 SEKSEKKESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKR 548
K ++ K+ KK + E+ + + E KK +K R
Sbjct: 185 ERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDR 226
Score = 36.2 bits (82), Expect = 0.16
Identities = 47/252 (18%), Positives = 91/252 (36%), Gaps = 28/252 (11%)
Query: 271 ITDSEASKP--KDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKA 328
++ S SKP + G + + E+E + + ++ +++ + K RE +K
Sbjct: 20 VSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKR 79
Query: 329 ESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWV 388
E G KEK +K + + +KE ++ + K +K TS +
Sbjct: 80 ERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERER---- 135
Query: 389 SGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRT 448
K + K K + + + K G +
Sbjct: 136 ---KEERKREERKERERKKEEREKERERKERKKRERKQVG-----------------EKE 175
Query: 449 ELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSE 508
E + E+ K + ++KE KKE + K ++K +R + Q ++ R E
Sbjct: 176 EERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKD-RQTNWREKE 234
Query: 509 KSEKKESKDTKK 520
+ K+E K+ KK
Sbjct: 235 RG-KRERKERKK 245
Score = 32.3 bits (72), Expect = 2.4
Identities = 26/112 (23%), Positives = 49/112 (43%), Gaps = 11/112 (9%)
Query: 263 LETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEAR 322
+ET K K + E+ + K+ ++ EK ++ E + GKKE + E+E +
Sbjct: 45 IETRKEGK-KERESERKKERRER-----EKRKREREKERKRERGKKEKKGERKKEERERK 98
Query: 323 -----ESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDK 369
+ +K+ E +K K KK T G+ + +E K + ++ K
Sbjct: 99 KRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERK 150
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 97.4 bits (241), Expect = 6e-20
Identities = 82/282 (29%), Positives = 145/282 (51%), Gaps = 56/282 (19%)
Query: 463 DPSKKEMKKEND---EKSSSRSSGDKKNTSDRSSKTQASVKKEEK-----RSSEKSEKKE 514
DP +KE ++ + ++ + + K R + +K+EE+ ++ E+ E+ +
Sbjct: 529 DPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMK 588
Query: 515 SKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRG 574
+ K+IE K + D E + + + KK+ ++K
Sbjct: 589 EEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAK---------------------- 626
Query: 575 RYEKIHGRSKEKERASLDK---KRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMEL 631
+ E++ R K++E A + + +++ R +E+L +K +EQ ERLR+A E
Sbjct: 627 KMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQ---------ERLRKAAEA 677
Query: 632 RRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERE-RMERERLERERIR 690
+R E E+ERRE+ER RE+E RE+ +RE+ER E ERQ E+E R E+ERL+ ER
Sbjct: 678 KRLAEQREQERREQER----REQERREQERREQERREQERQLAEQERRREQERLQAEREL 733
Query: 691 IEQER--RKEAERIAREREELRRQQQ-------QLRYEQEKR 723
E+E+ R + E++ RE EE +++++ QL+ EQEK+
Sbjct: 734 QEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKK 775
Score = 65.1 bits (157), Expect = 3e-10
Identities = 54/218 (24%), Positives = 106/218 (48%), Gaps = 21/218 (9%)
Query: 535 QTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKK 594
Q E++++ EE +++ + +++ K + R E++ + +ER K+
Sbjct: 536 QRLENLRRKEEAEQLRRQK------VEEDKRRRLEEVKLKREERLRKVLQARERVEQMKE 589
Query: 595 RDKDYRRKEILPF----EKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERE--RI 648
K ++ EK KE+RL E E+ ++ ++ E+ R ++E E R+
Sbjct: 590 EKKKQIEQKFAQIDEKTEKAKEERLAE-----EKAKKKAAAKKMEEVEARRKQEEEARRL 644
Query: 649 RIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREE 708
R +++ EE R Q ++ + E Q+ R+ E +RL +R EQERR E ER +ER E
Sbjct: 645 RWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQR---EQERR-EQERREQERRE 700
Query: 709 LRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKK 746
R++Q+ R ++ + +R R+ + + + E +K
Sbjct: 701 QERREQERREQERQLAEQERRREQERLQAERELQEREK 738
Score = 63.9 bits (154), Expect = 7e-10
Identities = 54/185 (29%), Positives = 96/185 (51%), Gaps = 40/185 (21%)
Query: 584 KEKERASLDKKRDKD----YRRKEILPFEKMKEQRLRE-HLVRFERLRRAMELRRRREIA 638
KEKER L+ R K+ RR+++ E+ K +RL E L R ERLR+ ++ R R E
Sbjct: 531 KEKERQRLENLRRKEEAEQLRRQKV---EEDKRRRLEEVKLKREERLRKVLQARERVEQM 587
Query: 639 ERERRER---------------ERIRIIREREERERLQRERERLEIER------------ 671
+ E++++ + R+ E+ +++ ++ E +E R
Sbjct: 588 KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWL 647
Query: 672 QKLERERMERERLERERIRIEQERRK--EAERIAREREELRRQQ---QQLRYEQEKRNSL 726
Q+ E ER +E L++++ ++ RK EA+R+A +RE+ RR+Q +Q R EQE+R
Sbjct: 648 QQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQE 707
Query: 727 KRPRD 731
+R ++
Sbjct: 708 RREQE 712
Score = 58.9 bits (141), Expect = 2e-08
Identities = 59/266 (22%), Positives = 117/266 (43%), Gaps = 32/266 (12%)
Query: 602 KEILPFEKMKEQRLREHLVRFERLRRAMELRR-------RREIAERERRERERIRIIRER 654
K P +++ R+ L R A +LRR RR + E + + ER+R + +
Sbjct: 521 KRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQA 580
Query: 655 EERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQ 714
ER +E ++ +IE QK + + E+ + ER+ E+ ++K A + E E R+Q++
Sbjct: 581 RERVEQMKEEKKKQIE-QKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 639
Query: 715 Q---LRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDA-RFGHGSDYSRQQNRFND 770
+ LR+ Q++ + + ++++ E ++L +A R + R++ +
Sbjct: 640 EARRLRWLQQEEEERRHQELLQKKKEE----EQERLRKAAEAKRLAEQREQERREQERRE 695
Query: 771 FDHRERGRFPESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSF--ERYPKNFSDSRR 828
+ RE+ ERR++ + E + A RRE ER + + R
Sbjct: 696 QERREQ--------------ERREQERREQERQLAEQERRREQERLQAERELQEREKALR 741
Query: 829 NEPPPPRNELRESDRREVRGERDERR 854
+ + EL E ++E + ER+
Sbjct: 742 LQKEQLQRELEEKKKKEEQQRLAERQ 767
Score = 41.6 bits (96), Expect = 0.004
Identities = 36/171 (21%), Positives = 73/171 (42%), Gaps = 6/171 (3%)
Query: 83 KGKKHEADELSGDASVEDDAFIKDCELENQEAHEQDGNDELKDSEEFGENEEENVHSKEL 142
K K+ E + L A + A ++ E QE EQ+ ++ + +E E E + +
Sbjct: 662 KKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERR 721
Query: 143 LSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKDIAGSG 202
E + EL E E ++KE ++ + E ++ E+ L + +EE+ +K +G
Sbjct: 722 REQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAG 781
Query: 203 DGTQEVSKPLPSEGSLAEADHTAHE-EMEAHTTVKEAEDDNISVTIQAEDA 252
SK L + T+++ + H + DN + + ++D+
Sbjct: 782 -----ASKALNVTVDVQSPACTSYQMTPQGHRAPPKINPDNYGMDLNSDDS 827
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 97.4 bits (241), Expect = 6e-20
Identities = 125/506 (24%), Positives = 205/506 (40%), Gaps = 64/506 (12%)
Query: 470 KKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKND 529
+KE+ SRS G + + + SS+T+ + + SE + + ++ EK
Sbjct: 517 RKEDTYPEESRSYG-RNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGS 575
Query: 530 NGASGQTSESIKKSE---EKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEK 586
G+ G +S + + S P ++ D R S +E+ HG +
Sbjct: 576 RGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSS---FERRHGERDRR 632
Query: 587 ERASLDKKRDKDYR---RKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERR 643
+ D++ R R + L ++ +E+R R V R RA E R RE R
Sbjct: 633 DNRERDQRPSSPIRHQGRNDELERDERREER-RVDRVDDRRDERARERDRERERDRERER 691
Query: 644 ERERIRIIREREERERLQRERER-LEIERQK-------------LERERMERERLERERI 689
ERER R RERE+ L+RER R E ER+K ERER E+ER
Sbjct: 692 ERERERD-REREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERE 750
Query: 690 RIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRP-RDVDHRRDDPYWSENKKLS 748
R +ER +E ER RERE R ++++ E++K +R D D RDD + +++
Sbjct: 751 REREERERERER-ERERERERERERERARERDKERERQRDWEDKDKGRDDRR-EKREEIR 808
Query: 749 LDTDARFGHGSDYSRQQNRF------NDFDHRERGRFPESSAVQSSSFERR-----DRFV 797
D + R GH S+++ R R R P+S A S + + V
Sbjct: 809 EDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVV 868
Query: 798 GQSEGKKARPTARRED-----PSFERYPKNFSDSRRNEPPPPRNELRESDRREVRGE--- 849
E + P+ ED +R P+ SRR E + ++ D++ + E
Sbjct: 869 RPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILE 928
Query: 850 --RDERRTVIIH------DRPDITHPRHPREAGPNPSRPTSWKSE-------GSMSTDKR 894
R + +I H + D H + ++A +P K E G++ T
Sbjct: 929 SSRMRAQDIIGHHQSEDRETSDRAHDENKKKA-KIQKKPIKKKKEDDVGIERGNIETTSE 987
Query: 895 ETRVERPERSGREVSGHSVRGAPPGN 920
+ +V P++ ++ S R G+
Sbjct: 988 DGQVFSPKKGQKKKSIEKKRKKSKGD 1013
Score = 79.3 bits (194), Expect = 2e-14
Identities = 124/515 (24%), Positives = 200/515 (38%), Gaps = 83/515 (16%)
Query: 465 SKKEMKKENDEKSSSRSSGDKKNTS--------DRSSKTQASVKKEEKRSS-------EK 509
S K K+++ KSSS S D+K ++ R+SKT S KK + S +
Sbjct: 215 SSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDI 274
Query: 510 SEKKESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCR 569
+ K+ K+ K++ + E+ + + ++ E++ + S SP + H
Sbjct: 275 ALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSS 334
Query: 570 PSRRGRYEKIHGRSKEKERA---SLDKKRDKDYRRK------EILPFEKMKEQRLREHLV 620
S+ G + H S ++R S + RR L + K+ R
Sbjct: 335 SSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSP 394
Query: 621 RFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERME 680
E+ R E R + +R RE R R+RE+ R +RE E+ + + +R
Sbjct: 395 MREKGRHDHE--RTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREP 452
Query: 681 RERLERERIRIEQERRK-EAERIAREREELRRQQQQLRYEQEKRNSLKRPRDV------- 732
R+ +R R ++RR+ R R+ E+R + + ++ R+S + RD
Sbjct: 453 RDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDS-RSTRDAHDYRDRE 511
Query: 733 ---DHRRDDPYWSENKKL--------SLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPE 781
HR++D Y E++ S T+ R + SR + R ND R RGR PE
Sbjct: 512 GRDTHRKEDTYPEESRSYGRNHLREESSRTEIR-NESRNESRSEIR-NDRMGRSRGRVPE 569
Query: 782 ----------SSAVQS--------------SSFERRDRFVGQSEGKKARPTARREDPSFE 817
S + S SS+ RDR+ + +AR D SFE
Sbjct: 570 LPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQAR------DSSFE 623
Query: 818 RY--PKNFSDSRRNE--PPPPRNELRESDRREVRGERDERRTVIIHDRPDITHPRHPREA 873
R ++ D+R + P P +D E R+ERR + DR D RE
Sbjct: 624 RRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRER 683
Query: 874 GPNPSRPTSWKSEGSMSTDK-RETRVERPERSGRE 907
+ R + E +K RE ER RE
Sbjct: 684 ERDRERERERERERDREREKERELERERARERERE 718
Score = 72.0 bits (175), Expect = 3e-12
Identities = 139/656 (21%), Positives = 247/656 (37%), Gaps = 109/656 (16%)
Query: 112 QEAHEQDGNDELKDSEEFGEN------------EEENVHSKELLSAEENKRAHELIEAEG 159
++ + +DG+DE K + + E + S S ++ H L+ ++
Sbjct: 809 EDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLL-SQV 867
Query: 160 IEDIEKEDIESQEI-EAQEG---EDDTFLTAQDGE---EEENEKDIAGSGDGTQEVSKPL 212
+ E + + E ++G E+D ++ EE+ K+ S D +E ++ L
Sbjct: 868 VRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEIL 927
Query: 213 PSEGSLAEADHTAHEEMEAHTTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKIT 272
S A+ D H + E T A D+N + I + D +E G N++ T
Sbjct: 928 ESSRMRAQ-DIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERG-NIETT 985
Query: 273 DSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGD 332
+DGQ SP+K K + K K + D ++EA + SKK
Sbjct: 986 S------EDGQ---VFSPKKGQKKKSIEKKRKKSKGDS----DISDEEAAQQSKKKRGPR 1032
Query: 333 KEKDTLKKG--PSSTGASGQAKSSSKESKDSKTSSKDDK------------GSTSSTSGS 378
T K+ G +G + S K+ + + D+ +T++T GS
Sbjct: 1033 TPPITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSDEDVPDRTEVTEAEHTATATTPGS 1092
Query: 379 SGSSTKNIW-----VSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMS 433
+ S ++ V+ ++ T A L S +T + S T +
Sbjct: 1093 TPSPLSSLLPPPPPVATATATTVPATLAATTAAAATSFSTSAITISTSATPTNTTNNTFA 1152
Query: 434 SSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSS 493
+ +C HRT VEKV+ E + RSS N S+RS
Sbjct: 1153 NEDSHRKC----HRTR-------VEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSH 1201
Query: 494 KTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKS 553
T ++ S+ +S +S + + + S + + E K RI
Sbjct: 1202 -TSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEIT-----GERKSRIDQLK 1255
Query: 554 PGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQ 613
G PSR ++ RS R+S + R R ++++E+
Sbjct: 1256 RGE-------------PSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQER 1302
Query: 614 RLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQK 673
EH R RE R+ R+RE +R+ + R R+R + ++
Sbjct: 1303 DRYEH-------------DRERERERRDTRQREW-----DRDADKDWPRNRDRDRLRERE 1344
Query: 674 LERERMERERLERERIR-----IEQERRKEAERI--AREREELRRQQQQLRYEQEK 722
ERER +R L+RER R +E++R ++ +R + + E ++R + +L E E+
Sbjct: 1345 RERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHER 1400
Score = 57.8 bits (138), Expect = 5e-08
Identities = 105/493 (21%), Positives = 176/493 (35%), Gaps = 117/493 (23%)
Query: 565 GDHCR----PSRRGR-YEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHL 619
G+ CR PS RG+ Y + RS E+ L E+MK +R
Sbjct: 54 GNTCRFVHGPSPRGKGYSSNYRRSPERPTGDLR---------------ERMKNKRQDVDT 98
Query: 620 VRFERLRRAMELRRRREIAERERRERERIRIIRER---EERERLQRERERLEIERQKLER 676
+R R+E + RE+E I+I +ER E E ++ E R + + +
Sbjct: 99 EPQKRNTEESSSPVRKESSRGRHREKEDIKITKERTPESEEENVEWETNRDDSDNGDINY 158
Query: 677 E-------RMERERLERERIRIEQERRKEAERIARERE--------------ELRRQQQQ 715
+ M+R++++RE +++EQE ++ E I ++E LR+ +
Sbjct: 159 DYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKS 218
Query: 716 LRYEQEKRNSLKRPRD----------VDHRRDDPYWSENKK--------LSLDTDARFG- 756
+ + ++S +D +D +R+ KK + D G
Sbjct: 219 PKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGK 278
Query: 757 ---------------------HGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDR 795
G D+ RQ+ + R++ R + S R
Sbjct: 279 KYKEKYKVKDRIEEKTRDGKDRGRDFERQREK------RDKPRSTSPAGQHHSPISSRHH 332
Query: 796 FVGQSEG---KKARPTARRE---DPSFER------------YPKN--FSDSRRNEPPPPR 835
G ++ P+ RR+ PS++R YP + S R+ PP R
Sbjct: 333 SSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHR 392
Query: 836 NELRESDRREVRGERDERRTVIIHDRPDITHPRHPREAGPNPSRPTSWKSEGSMSTDKRE 895
+ +RE R + ER + H+R + T + RE R ++ + S S D R+
Sbjct: 393 SPMREKGRHD--HERTSQSHDRRHERREDTRGKRDREKDSREER--EYEQDQSSSRDHRD 448
Query: 896 TRVERPERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVITDRGGGSQHYPEERH-VV 954
R R R R+ R +R R+ R R + H
Sbjct: 449 DREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYR 508
Query: 955 ERHGRDTSGPRKE 967
+R GRDT RKE
Sbjct: 509 DREGRDTH--RKE 519
Score = 55.5 bits (132), Expect = 3e-07
Identities = 77/431 (17%), Positives = 168/431 (38%), Gaps = 58/431 (13%)
Query: 457 VEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKE-- 514
V++V ++ +++ + + +++ DR + + +++E R E+ +KE
Sbjct: 665 VDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERD 724
Query: 515 -SKD-----------------TKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGH 556
+D K+ E + E+ + + ++ E++R +
Sbjct: 725 RERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKER 784
Query: 557 MVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLR 616
D D R RR + E+I R R D+++ K R E P + +R R
Sbjct: 785 ERQRDWEDKDKGRDDRREKREEI--REDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRR 842
Query: 617 EHLV----------RFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERER 666
EH + E+ R ++ R +E R R +EE + +R+
Sbjct: 843 EHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESS 902
Query: 667 LEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSL 726
E Q+L +E++ +RE+ I + R A+ I + R+ +++ K+ +
Sbjct: 903 RRYEEQEL-KEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAK 961
Query: 727 KRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGR----FPES 782
+ + + +++D E + +++T + G + Q + + R++ + +
Sbjct: 962 IQKKPIKKKKEDDVGIE--RGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDE 1019
Query: 783 SAVQSSSFER---------RDRFVGQSEGKKA--RPTARREDPSFERYPKNFSDSRRNEP 831
A Q S +R ++ V GK + ++ED +F ++SD E
Sbjct: 1020 EAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKEDTAF----SDWSD----ED 1071
Query: 832 PPPRNELRESD 842
P R E+ E++
Sbjct: 1072 VPDRTEVTEAE 1082
Score = 53.9 bits (128), Expect = 8e-07
Identities = 121/560 (21%), Positives = 203/560 (36%), Gaps = 78/560 (13%)
Query: 452 GQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSE 511
G L K K E +K N E+SSS +K +S + + +K ++R+ E E
Sbjct: 83 GDLRERMKNKRQDVDTEPQKRNTEESSSPV---RKESSRGRHREKEDIKITKERTPESEE 139
Query: 512 KKESKDTKKIEGKDEKNDNGASG-----QTSESIKKSEEKKRISSKSPGHM-----VILD 561
+ +T + + +DNG + S +K+ + ++ + +M +I+
Sbjct: 140 ENVEWETNR-----DDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIK 194
Query: 562 QTKGDHCRPSRRGRYEKIHGRSKEKERASLDK--KRDKDYRRKEILPFEKMKEQR-LREH 618
+ S+ + SK +R S K K R+ + + +QR + +
Sbjct: 195 KEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTN 254
Query: 619 LVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERER 678
+ + R E ++ +E+ ++ EE+ R ++R R + ERQ+ +R++
Sbjct: 255 QSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGR-DFERQREKRDK 313
Query: 679 MERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRD- 737
+ R + ++ ++R R ++ S +R RR
Sbjct: 314 PRSTSPAGQHHSPISSRHHSSS--SQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSA 371
Query: 738 DPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFV 797
PY S SL + R +Q + RE+GR S S +RR
Sbjct: 372 SPYPSH----SLSSPQR--------KQSPPRHRSPMREKGRHDHERT--SQSHDRRHERR 417
Query: 798 GQSEGKKARPTARREDPSFE------------RYPKNFSDSRRNEPPPPRNELRES---- 841
+ GK+ R RE+ +E R P++ D R R ELR+S
Sbjct: 418 EDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMR 477
Query: 842 ----------DRREVRGERDERRTVIIHD----------RPDITHPRHPREAGPNPSRPT 881
D +E R RD R T HD R + T+P R G N R
Sbjct: 478 DSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREE 537
Query: 882 SWKSEGSMSTDKRETRVE-RPERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVITDR 940
S ++E + + E+R E R +R GR G G+R S D
Sbjct: 538 SSRTE-IRNESRNESRSEIRNDRMGRS-RGRVPELPEKGSRGSRGSQIDSHSSNSNYHDS 595
Query: 941 GGGSQHYPEERHVVERHGRD 960
YPE ER RD
Sbjct: 596 WETRSSYPERDRYPERDNRD 615
Score = 40.0 bits (92), Expect = 0.011
Identities = 100/495 (20%), Positives = 184/495 (37%), Gaps = 59/495 (11%)
Query: 55 AIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFIKDCELENQEA 114
+ E G+ D + P+ P + +G+ DEL D E+ + + ++ A
Sbjct: 621 SFERRHGERDRRDNRERDQRPSS-PIRHQGRN---DELERDERREERRVDRVDDRRDERA 676
Query: 115 HEQDGNDELKDSEEFGENEEENVHSKELLSAEENKRAHELI-EAEGIEDIEKEDIESQEI 173
E+D E +D E E E E +E E +RA E E E D E++ +
Sbjct: 677 RERDRERE-RDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDR 735
Query: 174 EAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHT 233
E + + ++ E EE E++ + +E + E D + +
Sbjct: 736 ERERERERDREKEREREREERERERERERERERERER---ERERARERDKERERQRDWED 792
Query: 234 TVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASK--PKDGQDAIAQSPE 291
K +D ED DG D ++ K + S + + PK ++ SP+
Sbjct: 793 KDKGRDDRREKREEIREDRNPR--DGHDERKSKKRYRNEGSPSPRQSPKRRRE---HSPD 847
Query: 292 KESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQA 351
++ + + N K V+ +E+R S + D++ ++
Sbjct: 848 SDAYNSGDDKNEKHRLLSQVVR----PQESRSLSPSHLTEDRQGRWKEEDRKPERKESSR 903
Query: 352 KSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVL 411
+ +E K+ K SS D + + SS ++I S + + +D + K +
Sbjct: 904 RYEEQELKE-KVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKI 962
Query: 412 SAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKK 471
K + + +V ++ T GQ+ S KK KK
Sbjct: 963 QKKPIKKKK--------------EDDVGIERGNIETTSEDGQVFS--------PKKGQKK 1000
Query: 472 ENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKND-- 529
++ EK +S GD SD S ++ ++++S+KK T I K+E +
Sbjct: 1001 KSIEKKRKKSKGD----SDIS----------DEEAAQQSKKKRGPRTPPITTKEELVEMC 1046
Query: 530 NGASGQTSESIKKSE 544
NG +G +S KK +
Sbjct: 1047 NGKNGILEDSQKKED 1061
Score = 30.4 bits (67), Expect = 9.0
Identities = 50/311 (16%), Positives = 112/311 (36%), Gaps = 36/311 (11%)
Query: 59 EGGDPDNIELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFIKDCELENQEAHE-- 116
E G D+ + S D +++ +GK+ + + E D +++E +
Sbjct: 397 EKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGR 456
Query: 117 --QDGND-----------ELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDI 163
+D D +++DS E + + S++ + + AH+ + EG +
Sbjct: 457 DRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTH 516
Query: 164 EKEDIESQEIEA----QEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKP-LPSEGSL 218
KED +E + E+ + ++ E+ +I G P LP +GS
Sbjct: 517 RKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSR 576
Query: 219 A---------EADHTAHEEMEAHTTVKE----AEDDNISVTIQAEDAITLDFDGDDLLET 265
++ H+ E ++ E E DN QA D+ G+
Sbjct: 577 GSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRD---QARDSSFERRHGERDRRD 633
Query: 266 GKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESS 325
+ S + + D + + +E + + + +D + + + ++E
Sbjct: 634 NRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERER 693
Query: 326 KKAESGDKEKD 336
++ ++EK+
Sbjct: 694 ERERDREREKE 704
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 96.3 bits (238), Expect = 1e-19
Identities = 83/285 (29%), Positives = 145/285 (50%), Gaps = 58/285 (20%)
Query: 457 VEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEK-----RSSEKSE 511
VEK + K+E ++ + DK+ + + +K+EE+ ++ E+ E
Sbjct: 535 VEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLE-----EVKLKREERLRKVLQARERVE 589
Query: 512 KKESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPS 571
+ + + K+IE K + D E + + + KK+ ++K
Sbjct: 590 QMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAK------------------- 630
Query: 572 RRGRYEKIHGRSKEKERASLDK---KRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRA 628
+ E++ R K++E A + + +++ R +E+L +K +EQ ERLR+A
Sbjct: 631 ---KMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQ---------ERLRKA 678
Query: 629 MELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERE-RMERERLERE 687
E +R E E+ERRE+ER RE+E RE+ +RE+ER E ERQ E+E R E+ERL+ E
Sbjct: 679 AEAKRLAEQREQERREQER----REQERREQERREQERREQERQLAEQERRREQERLQAE 734
Query: 688 RIRIEQER--RKEAERIAREREELRRQQQ-------QLRYEQEKR 723
R E+E+ R + E++ RE EE +++++ QL+ EQEK+
Sbjct: 735 RELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKK 779
Score = 84.0 bits (206), Expect = 7e-16
Identities = 72/260 (27%), Positives = 133/260 (51%), Gaps = 17/260 (6%)
Query: 485 KKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTK--KIEGKDEKNDNGASGQTSESIKK 542
K+NT R + V+KE +R K+E++ + K+E + + E ++K
Sbjct: 521 KRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRK 580
Query: 543 S-EEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRR 601
+ ++R+ ++Q + + + E++ K K++A+ K + + RR
Sbjct: 581 VLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERL-AEEKAKKKAAAKKMEEVEARR 639
Query: 602 KEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERER----RERERIRIIREREER 657
K+ +E R L + E RR EL ++++ E+ER E +R+ RE+E R
Sbjct: 640 KQ------EEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERR 693
Query: 658 ERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREE-LRRQQQQL 716
E+ +RE+ER E ER+ E+ER E+ER E+ R ++ R +AER +ERE+ LR Q++QL
Sbjct: 694 EQERREQERREQERR--EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQL 751
Query: 717 RYEQEKRNSLKRPRDVDHRR 736
+ E E++ + + + R+
Sbjct: 752 QRELEEKKKKEEQQRLAERQ 771
Score = 57.4 bits (137), Expect = 7e-08
Identities = 57/255 (22%), Positives = 114/255 (44%), Gaps = 32/255 (12%)
Query: 613 QRLREHLVRFERLRRAMELRR-------RREIAERERRERERIRIIREREERERLQRERE 665
++ R+ L R A +LRR RR + E + + ER+R + + ER +E +
Sbjct: 536 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEK 595
Query: 666 RLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQ---LRYEQEK 722
+ +IE QK + + E+ + ER+ E+ ++K A + E E R+Q+++ LR+ Q++
Sbjct: 596 KKQIE-QKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQE 654
Query: 723 RNSLKRPRDVDHRRDDPYWSENKKLSLDTDA-RFGHGSDYSRQQNRFNDFDHRERGRFPE 781
+ + ++++ E ++L +A R + R++ + + RE+
Sbjct: 655 EEERRHQELLQKKKEE----EQERLRKAAEAKRLAEQREQERREQERREQERREQ----- 705
Query: 782 SSAVQSSSFERRDRFVGQSEGKKARPTARREDPSF--ERYPKNFSDSRRNEPPPPRNELR 839
ERR++ + E + A RRE ER + + R + + EL
Sbjct: 706 ---------ERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELE 756
Query: 840 ESDRREVRGERDERR 854
E ++E + ER+
Sbjct: 757 EKKKKEEQQRLAERQ 771
Score = 41.6 bits (96), Expect = 0.004
Identities = 36/171 (21%), Positives = 73/171 (42%), Gaps = 6/171 (3%)
Query: 83 KGKKHEADELSGDASVEDDAFIKDCELENQEAHEQDGNDELKDSEEFGENEEENVHSKEL 142
K K+ E + L A + A ++ E QE EQ+ ++ + +E E E + +
Sbjct: 666 KKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERR 725
Query: 143 LSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKDIAGSG 202
E + EL E E ++KE ++ + E ++ E+ L + +EE+ +K +G
Sbjct: 726 REQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAG 785
Query: 203 DGTQEVSKPLPSEGSLAEADHTAHE-EMEAHTTVKEAEDDNISVTIQAEDA 252
SK L + T+++ + H + DN + + ++D+
Sbjct: 786 -----ASKALNVTVDVQSPACTSYQMTPQGHRAPPKINPDNYGMDLNSDDS 831
Score = 38.1 bits (87), Expect = 0.043
Identities = 45/182 (24%), Positives = 86/182 (47%), Gaps = 14/182 (7%)
Query: 684 LERERIRIEQERRK-EAERIARER--EELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPY 740
+E+ER R+E RRK EAE++ R++ E+ RR+ ++++ ++E+R L++ R +
Sbjct: 535 VEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREER--LRKVLQA-RERVEQM 591
Query: 741 WSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERG--RFPESSAVQSSSFE-RRDRFV 797
E KK A+ ++ ++++ + ++ + E A + E RR R++
Sbjct: 592 KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWL 651
Query: 798 GQSEGKKARP--TARREDPSFERYPKNFSDSR---RNEPPPPRNELRESDRREVRGERDE 852
Q E ++ ++++ ER K R + E E RE +RRE E
Sbjct: 652 QQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQE 711
Query: 853 RR 854
RR
Sbjct: 712 RR 713
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 95.9 bits (237), Expect = 2e-19
Identities = 106/382 (27%), Positives = 172/382 (45%), Gaps = 66/382 (17%)
Query: 483 GDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSE---- 538
GD+K++ KT + +E+KR E+ EK E K K + +D K D+ G+ +
Sbjct: 2 GDEKDSW--KVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCME 59
Query: 539 -SIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDK 597
+I+ S ++ S + G K P + R EK+H R EK +K K
Sbjct: 60 ITIRNSPYRREDSMEDRGEEDDSLAIKP----PQQMSRKEKVHHRKDEK------RKEKK 109
Query: 598 DYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIA-ERERRER--ERIRIIRER 654
R KE ++ + +R + H ++ RR E ++RRE+A E RRER + + + R+R
Sbjct: 110 HARVKE----KEREHERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDR 165
Query: 655 EERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAE-------------- 700
E+ +RERER E+QK +RE+ ERER ER R E+E R+E
Sbjct: 166 LEQLERKRERERKMREQQKEQREQKERERRAEER-RKEREARREVSAHHRTMREDYSDKV 224
Query: 701 ----------RIAREREELRRQQQQLRYEQ-EKRNSLKRPRDVDHRRDDPYWSENKKLSL 749
R RER EL ++ ++ E+ E+R+ L +D+ SE K S
Sbjct: 225 KASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISD-------SERKTSSA 277
Query: 750 D-TDARFGHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFVGQSEGKKARPT 808
+ + A G GS+ ++ + E G E S + E + G + + + +
Sbjct: 278 ESSSAESGSGSEEEEEEEE----EEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQS 333
Query: 809 ARREDPSFERYPKNFSDSRRNE 830
A E+ S E ++ + R NE
Sbjct: 334 A--EEVSEEEMSED--EERENE 351
Score = 57.4 bits (137), Expect = 7e-08
Identities = 82/399 (20%), Positives = 153/399 (38%), Gaps = 77/399 (19%)
Query: 582 RSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHL----VRFERLRRAMELRRRRE- 636
R +++E+A + + ++ D R + + ++E LR+H +R RR + R E
Sbjct: 23 RKEQEEKAEIKRLKNSDDRDSKR---DSLEEGELRDHCMEITIRNSPYRREDSMEDRGEE 79
Query: 637 ---IAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQ 693
+A + ++ R + R++ +R +E++ ++ ++ E ER +R R E+++ R E
Sbjct: 80 DDSLAIKPPQQMSRKEKVHHRKDEKR--KEKKHARVKEKEREHERRKRHREEQDKARREW 137
Query: 694 ERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDA 753
ER+K E +ARE R + +++ L+R R+ + +
Sbjct: 138 ERQKRRE-MAREHSRRERGNDGVCLFRDRLEQLERKRERERKM----------------- 179
Query: 754 RFGHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFVGQSEGKKARPTARRED 813
+ ++Q + + R R E A + S R RED
Sbjct: 180 -----REQQKEQREQKERERRAEERRKEREARREVSAHHR---------------TMRED 219
Query: 814 PSFERYPKNFSDSRRNEPPPPRNELRESD-RREVRGERDERRTVIIHDRPDITHPRHPRE 872
S + ++S R+ P PPR D R+ V+ E+ E R ++ D DI+
Sbjct: 220 YSDKVKASHWS---RSPPRPPRERFELGDGRKPVKEEKMEERD-LLSDLQDISDSERKTS 275
Query: 873 AGPNPSRPTSWKSE---------------GSMSTDKRETRVERPERSGREVSGHSVRGAP 917
+ + S + SE S ++ E E E +G S + A
Sbjct: 276 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 335
Query: 918 PGNRSSASGYGSREGDRGVIT------DRGGGSQHYPEE 950
+ S RE + ++ DR G EE
Sbjct: 336 EVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 374
Score = 43.9 bits (102), Expect = 8e-04
Identities = 30/136 (22%), Positives = 65/136 (47%), Gaps = 23/136 (16%)
Query: 464 PSKKEMKKENDEKSSSR--SSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKI 521
P K+E +E D S + S ++K +S SS ++ EE+ E+ E++E +++
Sbjct: 249 PVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 308
Query: 522 EGKDEK----------NDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPS 571
E ++E+ N AS Q++E + + E + ++ H++++ ++
Sbjct: 309 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES-------- 360
Query: 572 RRGRYEKIHGRSKEKE 587
R+++ G S+E E
Sbjct: 361 ---RFDRDSGESEEAE 373
Score = 43.5 bits (101), Expect = 0.001
Identities = 39/133 (29%), Positives = 65/133 (48%), Gaps = 19/133 (14%)
Query: 93 SGDASVEDDAFIKDCELENQEAHEQDG--NDELKDSEEFGENEEENVHSKELLSAEENKR 150
S ++S + + E E +E E++G ++E ++ EE E EEE S ++E++
Sbjct: 276 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQS-- 333
Query: 151 AHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSK 210
A E+ E E ED E+E+ E+ + E D GE EE E+++ G+GT
Sbjct: 334 AEEVSEEEMSEDEEREN-ENHLLVVPESRFD----RDSGESEEAEEEV---GEGT----- 380
Query: 211 PLPSEGSLAEADH 223
P +L E D+
Sbjct: 381 --PQSSALTEGDY 391
Score = 40.4 bits (93), Expect = 0.009
Identities = 51/293 (17%), Positives = 109/293 (37%), Gaps = 15/293 (5%)
Query: 83 KGKKHEADELSGDASVEDD--AFIKDCELENQEAHEQDGNDELKDSEEFGENEEENVHSK 140
+ + ++ D EDD A ++ +E +++ K+ + E+E H +
Sbjct: 63 RNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHER 122
Query: 141 ELLSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKDIAG 200
EE +A E + ++ ++ + + G D L E+ E +++
Sbjct: 123 RKRHREEQDKARREWERQ-----KRREMAREHSRRERGNDGVCLFRDRLEQLERKRERER 177
Query: 201 SGDGTQEVSKPLPSEGSLAEA---DHTAHEEMEAH-TTVKEAEDDNISVTIQAEDAITLD 256
Q+ + AE + A E+ AH T++E D + + +
Sbjct: 178 KMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPP 237
Query: 257 FDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDP 316
+ +L + K VK E I+ S K S +A G +E+ +
Sbjct: 238 RERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEE----EE 293
Query: 317 VEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDK 369
E+E E +E ++E++ ++ TG++ + S + S+ +D+
Sbjct: 294 EEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDE 346
Score = 37.7 bits (86), Expect = 0.056
Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 11/110 (10%)
Query: 133 EEENVHSKELLS-------AEENKRAHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLT 185
+EE + ++LLS +E + E AE E+E+ E +E E +EG
Sbjct: 251 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEE-EEEEGSTSEESE 309
Query: 186 AQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTV 235
++ EEEE E++ +G ++E S+ E S E E E H V
Sbjct: 310 EEEEEEEEEEEE---TGSNSEEASEQSAEEVSEEEMSEDEERENENHLLV 356
Score = 30.8 bits (68), Expect = 6.9
Identities = 26/135 (19%), Positives = 55/135 (40%), Gaps = 2/135 (1%)
Query: 117 QDGNDELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQ 176
+D +D++K S EL + + ++ E + + D++ DI E +
Sbjct: 218 EDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ--DISDSERKTS 275
Query: 177 EGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVK 236
E + + EEEE E++ T E S+ E E + ++ E + + +
Sbjct: 276 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 335
Query: 237 EAEDDNISVTIQAED 251
E ++ +S + E+
Sbjct: 336 EVSEEEMSEDEEREN 350
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 93.6 bits (231), Expect = 9e-19
Identities = 133/588 (22%), Positives = 233/588 (39%), Gaps = 89/588 (15%)
Query: 264 ETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDP----VEK 319
E K K + S +S D + +S D E K K++ + + EK
Sbjct: 186 EEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEK 245
Query: 320 EARESSKKAESGDKEKDTLKKGPSSTGASGQ-----------AKSSSK-ESKDSKTSSKD 367
+ R+ SKK+ S + E + L+ P ST + KS K + K+ K ++
Sbjct: 246 KKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERE 305
Query: 368 DKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCY 427
+ + + S + + V+ + G+ + + R+P
Sbjct: 306 RERECNPPNSQPASYQRRLLVT----------------RSGRKIKGRGPRRYRTPSRS-- 347
Query: 428 GIVTMSSSTEVSRCIAHLHRTELHGQLISVEK----VKGDPSKKEMKKENDE---KSSSR 480
S H + Q + V +KGD S+ KEN + R
Sbjct: 348 ---RSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKER 404
Query: 481 SSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQT-SES 539
D +N S+ ++ +KE+K KS KE +D ++ KD+K N + S+S
Sbjct: 405 KITDHRNVSESPNRKN---EKEKKVKDHKSNSKE-RDIRRNSEKDDKYKNKVKKRAKSKS 460
Query: 540 IKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDY 599
KS+EK + + H ++ + R +GR H KEKE+ S K +D++
Sbjct: 461 RSKSKEKSKSKERDSKH----NRNEEKRMRSRSKGR---DHENVKEKEKQSDSKGKDQER 513
Query: 600 RRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAE---------RER-RERERIR 649
R + + + +H E+ RRA R +I + RER R R+R R
Sbjct: 514 SRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSR 573
Query: 650 IIRER---EERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIARER 706
+R R +R R + E E ++ R R R R R + RR+ + + ER
Sbjct: 574 RVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSER 633
Query: 707 EELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQN 766
EE + + + QE ++S HR+++ SE++K + + +R + S+ SR++
Sbjct: 634 EESQSRNKDKYRNQESKSS--------HRKEN---SESEK-RMYSKSRDHNSSNNSREKK 681
Query: 767 RFNDFDHRERGRFPESSAVQSS-SFERRDRFVGQSEGKKARPTARRED 813
+R + P S QSS E + + E +K R + +E+
Sbjct: 682 -------ADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKEN 722
Score = 84.7 bits (208), Expect = 4e-16
Identities = 122/521 (23%), Positives = 208/521 (39%), Gaps = 79/521 (15%)
Query: 452 GQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQA----SVKKEEKRSS 507
G+LI KVK K+E K+ SSS SS D ++SD S + + S +E+ +
Sbjct: 175 GELIPKSKVK----KEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKR 230
Query: 508 EKSEKKESKDTKKIEGKDEKNDNGASGQTS--------------ESIKKSEEKKRISSKS 553
+K +K S+ KK + K +K+ AS ++ E I E + + KS
Sbjct: 231 KKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKS 290
Query: 554 P-----GHMVILDQTKGDHCRP--------------SRRGRYEKIHGRSKEKERA-SLDK 593
P ++ + C P +R GR KI GR + R S +
Sbjct: 291 PPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGR--KIKGRGPRRYRTPSRSR 348
Query: 594 KRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERER---RERER-IR 649
RD+ +RR E P + + QR + V + EI E +R R +ER I
Sbjct: 349 SRDR-FRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKIT 407
Query: 650 IIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREEL 709
R E + E+E+ + + +ER R E++ + + + +K A+ +R + +
Sbjct: 408 DHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDD-KYKNKVKKRAKSKSRSKSKE 466
Query: 710 RRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKL--SLDTDARFGHGSDYSRQ-QN 766
+ + ++ R + RN KR R RD E +K S D + S+Q ++
Sbjct: 467 KSKSKE-RDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLES 525
Query: 767 RFNDFDH---RERGRFPESSAVQ------SSSFERRDRFVGQSEGKKARPTARRED---- 813
+ N+ DH +E+ R +S + + S+ R R +S + R +R D
Sbjct: 526 KSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRS 585
Query: 814 --PSFERY------PKNFSDSRRNEPPPPRNELRESDRREVRGERDERRTVIIHD----R 861
+ RY + S SR PP R+ ++ RR ER + R
Sbjct: 586 RSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYR 645
Query: 862 PDITHPRHPREAGPNPSRPTSWKSEGSMSTDKRETRVERPE 902
+ H +E + R S + + S + RE + +R +
Sbjct: 646 NQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQ 686
Score = 76.6 bits (187), Expect = 1e-13
Identities = 66/312 (21%), Positives = 125/312 (40%), Gaps = 35/312 (11%)
Query: 458 EKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKD 517
EK K K KE D + +S KN + +K+++ K +EK S++ + K +++
Sbjct: 421 EKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRN 480
Query: 518 TKK-----IEGKDEKN------DNGASGQTSESIKKSEEKKRISSKSPGH---------- 556
+K +G+D +N + + G+ E + E+ K++ SKS H
Sbjct: 481 EEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDR 540
Query: 557 -----MVILDQTKGDHCRPSRRGRYEKIHGRSKEKERAS--LDKKRDKDYRRKEILPFEK 609
D TKG H SR + RS+ + D+ R K+Y R + +
Sbjct: 541 RAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRR 600
Query: 610 MKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEI 669
R RE R R RRRR+ ER E + + R + + +E E
Sbjct: 601 RGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSES 660
Query: 670 ERQKLERER-------MERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEK 722
E++ + R ++ +R++ + ++ + + ++ +++R EK
Sbjct: 661 EKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEK 720
Query: 723 RNSLKRPRDVDH 734
N + ++ DH
Sbjct: 721 ENQKSKGQENDH 732
Score = 64.7 bits (156), Expect = 4e-10
Identities = 71/361 (19%), Positives = 149/361 (41%), Gaps = 19/361 (5%)
Query: 269 VKITDSEASKPKDGQDAIAQSPEKESKDYE--MNANHKDGKKEDCVKGDPVEKEARESSK 326
+K SE ++ K+ Q + + E++ D+ + ++ +KE VK + R+ +
Sbjct: 381 IKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRR 440
Query: 327 KAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNI 386
+E DK K+ +KK S S + S + +DSK + ++K S + G + K
Sbjct: 441 NSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEK 500
Query: 387 WVSGLS---------SNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTE 437
S S K+ L++ ++ S + A+S +C +T +
Sbjct: 501 EKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSREC--DITKGKHSY 558
Query: 438 VSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQA 497
SR + ++ S + KE + +++ R + ++++
Sbjct: 559 NSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRS 618
Query: 498 SVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKR---ISSKSP 554
++ +R S SE++ES+ K + +++++ + + SES K+ K R S+ S
Sbjct: 619 KDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSR 678
Query: 555 GHMVILDQTKGDHCRPSRRGRYEK---IHGRSKEKERASLDKKRDKDYRRKEILPFEKMK 611
DQ+ + S + K + + EK R+S++K+ K ++ EK K
Sbjct: 679 EKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNK 738
Query: 612 E 612
+
Sbjct: 739 K 739
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 88.6 bits (218), Expect = 3e-17
Identities = 111/514 (21%), Positives = 206/514 (40%), Gaps = 72/514 (14%)
Query: 116 EQDGNDELKDSEEFGENEEENVHSKELLSAEENKRAHEL----IEAEGIEDIEKEDIESQ 171
E+ G KDS++ G + N SK+++ E+ KR +E +++ + K+ S
Sbjct: 121 EKGGTPLKKDSKKKGGSYATNPESKQIVE-EKTKRQNEADKTPLKSSHENEQSKKSKSSS 179
Query: 172 EIEAQEGEDDTF---LTAQDGEEEENEKD-----IAGSGDGTQEVSKPLPSEGSLAEADH 223
E + T + +D ++ +N K + + +++ + S ++E
Sbjct: 180 ETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICS 239
Query: 224 TAHEEMEAHTTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQ 283
++ V +++D++I+ + + L T K T A K D +
Sbjct: 240 ENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAE 299
Query: 284 DAIAQSPEKESKDYEMNANHKDGKKE--------DCVKGDPVE--KEARESSKKAESGDK 333
++ +K+SK + N D KK+ D GD + K+ ++ KK + DK
Sbjct: 300 SEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDK 359
Query: 334 EKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSS 393
+KDT K S+ SG AK + +S++ K +SK+D + + + +++ S S
Sbjct: 360 KKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQ 419
Query: 394 NTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQ 453
+ D K+ K + K V N ST+
Sbjct: 420 KDEKKDKKD-----SKTDNKKSVKNDEE-------------STDAD-------------- 447
Query: 454 LISVEKVKGDPSK---KEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKE-----EKR 505
+ KGD K E K + D K + KKN ++ +KK+ EK+
Sbjct: 448 ----SEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKK 503
Query: 506 SSEKSEKKES-KDTKKIEGK-DEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQT 563
S+K KK++ KDT+ + + DE + G +TS IK S+ + S PG +D++
Sbjct: 504 GSKKDIKKDARKDTESTDAEFDESSKTGF--KTSTKIKGSDTESEESLYKPGAKKKIDES 561
Query: 564 KGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDK 597
G G E G ++ + ++K +K
Sbjct: 562 DGTSANSKMEG-LESKRGFRMSSKKTTFNEKGEK 594
Score = 42.0 bits (97), Expect = 0.003
Identities = 77/483 (15%), Positives = 198/483 (40%), Gaps = 66/483 (13%)
Query: 444 HLHRTELHGQLISVEKVK----GDPSKKEMKKEN-------------DEKSSSRSSGDK- 485
HL+ ++ H + +K K G P KK+ KK+ +EK+ ++ DK
Sbjct: 102 HLYTSKTHLKKAEYKKSKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKT 161
Query: 486 ------KNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSES 539
+N + SK+ + E + S S+ KD K + K+ K N T +
Sbjct: 162 PLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKK--DSKNSKKTNTEFLHTKNN 219
Query: 540 IKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDY 599
KK ++ + S+ + + D + E I + + + + K+Y
Sbjct: 220 PKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDESI---NFDAWLRNYSQNNSKNY 276
Query: 600 RRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERI-RIIREREERE 658
K +K ++ ++ E ++ +++ +++ + +++ ++++
Sbjct: 277 SLKYTKYTKKDTKKNAKK------------SSDAESEDSKDAKKDSKKVKKNVKKDDKKK 324
Query: 659 RLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRY 718
++++ E + E + ER + ++ ++++++ + +++K+ ++ + + R
Sbjct: 325 DVKKDTESTDAESGDSKDERKDTKK-DKKKLK-KDDKKKDTKKYPESTDTESGDAKDAR- 381
Query: 719 EQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHR---E 775
+ RN K ++ D ++D KK++ TD+ S S++ + + D + +
Sbjct: 382 -NDSRNLKKASKNDDKKKD------AKKITFSTDSESELESKESQKDEKKDKKDSKTDNK 434
Query: 776 RGRFPESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSDSRRN-EPPPP 834
+ + + + S + D G+ + KK + ++++D D+++N E
Sbjct: 435 KSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKK--------KDAKKNAESTEM 486
Query: 835 RNELR-ESDRREVRGERDERRTVIIHDRPDITHPRHPREAGPNPSRPTSWKSEGSMSTDK 893
++L + D++ + ++ ++ + R D + TS K +GS T+
Sbjct: 487 ESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGS-DTES 545
Query: 894 RET 896
E+
Sbjct: 546 EES 548
Score = 40.0 bits (92), Expect = 0.011
Identities = 46/218 (21%), Positives = 100/218 (45%), Gaps = 22/218 (10%)
Query: 29 DLKSELKRRNLDITGVKTVLISRLKQAIEEEGGDPDNIELTVSTDTPN-KKPTKGKGKKH 87
D K + K+ D T + ++ + E GD + D+ N KK +K KK
Sbjct: 346 DTKKDKKKLKKDDKKKDT---KKYPESTDTESGDAKDAR----NDSRNLKKASKNDDKKK 398
Query: 88 EADELSGDASVEDDAFIKDCELENQEAHEQDGNDELKDSEEFGENEEENVHSKELLSAEE 147
+A +++ E + K E+Q+ ++D D D+++ +N+EE+ + +
Sbjct: 399 DAKKITFSTDSESELESK----ESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDS 454
Query: 148 NKRAHELIEAEGIEDIEKEDIE---SQEIEAQEGEDDTFLTAQDGEEEENEKDIAGSGDG 204
K + E +G +D +K+D + + E+ E E D L +++++ K+ GS
Sbjct: 455 KKGKKD--EKKGKKDSKKDDKKKDAKKNAESTEMESDLELK----KDKKHSKEKKGSKKD 508
Query: 205 TQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAEDDN 242
++ ++ +E + AE D ++ + T +K ++ ++
Sbjct: 509 IKKDARK-DTESTDAEFDESSKTGFKTSTKIKGSDTES 545
Score = 38.1 bits (87), Expect = 0.043
Identities = 41/145 (28%), Positives = 60/145 (41%), Gaps = 23/145 (15%)
Query: 71 STDTPNKKPTKGKGKKHEADELSGDASVEDDAFIKDCELENQEAHEQDGNDELKDSEEFG 130
STD ++ KG KK + DE G + D KD + +N E+ E + + ELK
Sbjct: 443 STDADSEP--KGDSKKGKKDEKKGKKDSKKDDKKKDAK-KNAESTEMESDLELK------ 493
Query: 131 ENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLTAQDGE 190
++ HSK E K + + I+ + +D E D E E + T + D E
Sbjct: 494 ---KDKKHSK------EKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTE 544
Query: 191 EEEN-----EKDIAGSGDGTQEVSK 210
EE+ K DGT SK
Sbjct: 545 SEESLYKPGAKKKIDESDGTSANSK 569
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 87.8 bits (216), Expect = 5e-17
Identities = 67/260 (25%), Positives = 126/260 (48%), Gaps = 49/260 (18%)
Query: 478 SSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTS 537
SSR++ S + S ++ S K E++E + K+ K+ K + G
Sbjct: 6 SSRAAVKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERG------ 59
Query: 538 ESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDK 597
K E+KKR K R KE+ER K++++
Sbjct: 60 ----KKEKKKR-----------------------------KKRERGKERER----KRKER 82
Query: 598 DYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREER 657
+ +RKE E+ K ++ ++ R +R RR + ++ R+ ERE ++R + + R+++
Sbjct: 83 EKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKK 142
Query: 658 ERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLR 717
R +R+RE+ ER K ER+R +R++ ERE+ ++ER ++ + RER+E R ++++ +
Sbjct: 143 RRKERKREK---ERGKRERKRKKRKKEEREK---KRERNRKERKKERERKERRERKKERK 196
Query: 718 YEQEKRNSLKRPRDVDHRRD 737
E+ K+ K+ R D + D
Sbjct: 197 KERRKKKERKKDRKTDRQTD 216
Score = 87.0 bits (214), Expect = 8e-17
Identities = 79/254 (31%), Positives = 127/254 (50%), Gaps = 42/254 (16%)
Query: 465 SKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGK 524
S + K N E S K + R S+ +K+E+R EK +++ K+ K+ GK
Sbjct: 6 SSRAAVKLNTELQMVSCSHISKPCTQRESE-----RKKERREREKRKREREKERKRERGK 60
Query: 525 DEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSK 584
EK + E +K +E+++ R+ R EK R +
Sbjct: 61 KEKKKRKKRERGKERERKRKEREK----------------------QRKERREK-ERRKR 97
Query: 585 EKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLR--RAMELRRRREIAERER 642
+KE+ KKR++ R + +K +++R RE+ R ER R R + RR+ E+ER
Sbjct: 98 KKEK----KKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKER 153
Query: 643 RERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERI 702
+RER R R++EERE+ +RER R E +K ERER ER ++ER ++ERRK+ ER
Sbjct: 154 GKRERKRKKRKKEEREK-KRERNRKE---RKKERERKERRERKKER---KKERRKKKER- 205
Query: 703 AREREELRRQQQQL 716
++R+ R+ Q+
Sbjct: 206 KKDRKTDRQTDSQV 219
Score = 77.4 bits (189), Expect = 6e-14
Identities = 63/206 (30%), Positives = 110/206 (53%), Gaps = 24/206 (11%)
Query: 608 EKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERL 667
E+ KE+R RE R ER + R ++E +R++RER + R R+R+ERE+ + +ER
Sbjct: 35 ERKKERREREKRKR-EREKERKRERGKKEKKKRKKRERGKERE-RKRKEREK--QRKERR 90
Query: 668 EIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLK 727
E ER+K ++E+ +RER +R R +ER+K+ ER RERE +R++++ + ++K+ +
Sbjct: 91 EKERRKRKKEKKKRERKQRGR----RERKKKKERKERERENKQRRERKRKKRRKKKRRKE 146
Query: 728 RPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPESSAVQS 787
R R+ + + + + KK + R++NR +ER + E +
Sbjct: 147 RKREKERGKRERKRKKRKK----------EEREKKRERNR------KERKKERERKERRE 190
Query: 788 SSFERRDRFVGQSEGKKARPTARRED 813
ER+ + E KK R T R+ D
Sbjct: 191 RKKERKKERRKKKERKKDRKTDRQTD 216
Score = 65.9 bits (159), Expect = 2e-10
Identities = 54/221 (24%), Positives = 104/221 (47%), Gaps = 50/221 (22%)
Query: 458 EKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKD 517
+K + + K++ ++E + K R G K+ + K + ++E KR + ++KE ++
Sbjct: 37 KKERREREKRKREREKERK---RERGKKE--KKKRKKRERGKERERKRKEREKQRKERRE 91
Query: 518 TKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYE 577
++ + K EK KK E K+R RR R +
Sbjct: 92 KERRKRKKEK-------------KKRERKQR----------------------GRRERKK 116
Query: 578 KIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREI 637
K + +E+E +++ K R+K K +++R RE ER +R + ++R++
Sbjct: 117 KKERKERERENKQRRERKRKKRRKK------KRRKERKREK----ERGKRERKRKKRKKE 166
Query: 638 AERERRERERIRIIREREERERLQRERERLEIERQKLERER 678
++RER R +ERE +ER +R++ER + R+K ER++
Sbjct: 167 EREKKRERNRKERKKERERKERRERKKERKKERRKKKERKK 207
Score = 59.3 bits (142), Expect = 2e-08
Identities = 57/212 (26%), Positives = 97/212 (45%), Gaps = 56/212 (26%)
Query: 642 RRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAER 701
+RE ER + RERE+R+R +RE+ER +RER ++E+ +R++ +ER KE ER
Sbjct: 31 QRESERKKERREREKRKR-EREKER--------KRERGKKEKKKRKK----RERGKERER 77
Query: 702 IAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDY 761
+ERE+ R+++++ + K+ KR R
Sbjct: 78 KRKEREKQRKERREKERRKRKKEKKKRER------------------------------- 106
Query: 762 SRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERYPK 821
+Q+ R RER + E + + +RR+R + KK R +RE +R K
Sbjct: 107 -KQRGR------RERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERK 159
Query: 822 NFSDSRRNEPPPPRNELRESDRREVRGERDER 853
R+ R + RE +R+E + ER+ +
Sbjct: 160 -----RKKRKKEEREKKRERNRKERKKERERK 186
Score = 50.8 bits (120), Expect = 6e-06
Identities = 38/181 (20%), Positives = 83/181 (45%), Gaps = 2/181 (1%)
Query: 675 ERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDH 734
E ER ++ER ERE+ + E+E+ ++ ER +E+++ +++++ E++++ K+ ++
Sbjct: 33 ESER-KKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91
Query: 735 RRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRD 794
+ E KK R R++ + RER R + +R+
Sbjct: 92 KERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKE-RKRE 150
Query: 795 RFVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRESDRREVRGERDERR 854
+ G+ E K+ + + ER K R + R + R+ +RR+ + + +R+
Sbjct: 151 KERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRK 210
Query: 855 T 855
T
Sbjct: 211 T 211
Score = 48.1 bits (113), Expect = 4e-05
Identities = 43/181 (23%), Positives = 77/181 (42%), Gaps = 13/181 (7%)
Query: 458 EKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKD 517
+K K K+E KE + K R K+ K + KK E++ + E+K+ K+
Sbjct: 60 KKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKE 119
Query: 518 TKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYE 577
K+ ++ +N + + KK K+R K G + + R +R R
Sbjct: 120 RKE---RERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNR 176
Query: 578 KIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREI 637
K R KE+ER +++ R+KE + K++R ++ + +R + R RE
Sbjct: 177 K--ERKKERER------KERRERKKERKKERRKKKERKKDR--KTDRQTDSQVFRPLRES 226
Query: 638 A 638
A
Sbjct: 227 A 227
Score = 31.6 bits (70), Expect = 4.0
Identities = 23/97 (23%), Positives = 42/97 (43%), Gaps = 1/97 (1%)
Query: 273 DSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGD 332
+SE K + ++ + EKE K K KK + K +++ RE +K E +
Sbjct: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRK-ERRE 91
Query: 333 KEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDK 369
KE+ KK + + K+ K+ K +++K
Sbjct: 92 KERRKRKKEKKKRERKQRGRRERKKKKERKERERENK 128
>gi|134152708 arginine and glutamate rich 1 [Homo sapiens]
Length = 273
Score = 86.3 bits (212), Expect = 1e-16
Identities = 69/270 (25%), Positives = 129/270 (47%), Gaps = 29/270 (10%)
Query: 476 KSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQ 535
+S SRSS K+T +SSK + RS +K ++ +++ + + S
Sbjct: 3 RSRSRSSSRSKHT--KSSKHNKKRSRSRSRSRDKERVRKRSKSRESKRNRRRESRSRSRS 60
Query: 536 TSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKR 595
T+ ++ + E + +S P + I +T S+R ++ R +E+++A +++R
Sbjct: 61 TNTAVSRRERDRERASSPPDRIDIFGRT------VSKRSSLDEKQKREEEEKKAEFERQR 114
Query: 596 DKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIR-IIRER 654
K+++Q + E L+ E RR EL +R E E+R+ E R ++R
Sbjct: 115 -------------KIRQQEIEEKLIEEETARRVEELVAKRVEEELEKRKDEIEREVLRRV 161
Query: 655 EERERLQRERERLEIERQK-----LERERMERERLERERIR--IEQERRKEAERIARERE 707
EE +R+ ++ E+ERQ+ ++ R E ER +RE + +E+ RK AE A+ E
Sbjct: 162 EEAKRIMEKQLLEELERQRQAELAAQKAREEEERAKREELERILEENNRKIAEAQAKLAE 221
Query: 708 ELRRQQQQLRYEQEKRNSLKRPRDVDHRRD 737
E R ++ R E+R L++ R + +
Sbjct: 222 EQLRIVEEQRKIHEERMKLEQERQRQQKEE 251
Score = 84.3 bits (207), Expect = 5e-16
Identities = 71/278 (25%), Positives = 132/278 (47%), Gaps = 39/278 (14%)
Query: 476 KSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQ 535
+SSSRS K + ++ S ++++R ++S+ +ESK ++ E + S
Sbjct: 7 RSSSRSKHTKSSKHNKKRSRSRSRSRDKERVRKRSKSRESKRNRRRESRSR------SRS 60
Query: 536 TSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKR 595
T+ ++ + E + +S P + I +T S+R ++ R +E+++A +++R
Sbjct: 61 TNTAVSRRERDRERASSPPDRIDIFGRTV------SKRSSLDEKQKREEEEKKAEFERQR 114
Query: 596 DKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIR-IIRER 654
K+++Q + E L+ E RR EL +R E E+R+ E R ++R
Sbjct: 115 -------------KIRQQEIEEKLIEEETARRVEELVAKRVEEELEKRKDEIEREVLRRV 161
Query: 655 EERERLQRERERLEIERQK-----LERERMERERLERERIR--IEQERRKEAERIARERE 707
EE +R+ ++ E+ERQ+ ++ R E ER +RE + +E+ RK AE A+ E
Sbjct: 162 EEAKRIMEKQLLEELERQRQAELAAQKAREEEERAKREELERILEENNRKIAEAQAKLAE 221
Query: 708 ELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENK 745
E QLR +E+R + ++ R E K
Sbjct: 222 E------QLRIVEEQRKIHEERMKLEQERQRQQKEEQK 253
Score = 45.8 bits (107), Expect = 2e-04
Identities = 53/239 (22%), Positives = 102/239 (42%), Gaps = 57/239 (23%)
Query: 465 SKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGK 524
S++E +E R + S RSS + ++EE++ +E +++ +
Sbjct: 66 SRRERDRERASSPPDRIDIFGRTVSKRSSLDEKQKREEEEKKAEFERQRKIRQQ------ 119
Query: 525 DEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSK 584
+ E + + E +R+ E++ +
Sbjct: 120 ----------EIEEKLIEEETARRV---------------------------EELVAKRV 142
Query: 585 EKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRE 644
E+E L+K++D + R+ + E+ K ++ L ER R+A EL ++ E ER +
Sbjct: 143 EEE---LEKRKD-EIEREVLRRVEEAKRIMEKQLLEELERQRQA-ELAAQKAREEEERAK 197
Query: 645 RERIRIIREREERE------RLQRERERLEIERQKLERERMERERLERERIRIEQERRK 697
RE + I E R+ +L E+ R+ E++K+ ERM +LE+ER R ++E +K
Sbjct: 198 REELERILEENNRKIAEAQAKLAEEQLRIVEEQRKIHEERM---KLEQERQRQQKEEQK 253
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 85.9 bits (211), Expect = 2e-16
Identities = 98/380 (25%), Positives = 162/380 (42%), Gaps = 47/380 (12%)
Query: 483 GDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSE---- 538
GD+K++ KT + +E+KR E+ EK E K K + +D K D+ G+ +
Sbjct: 2 GDEKDSW--KVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRME 59
Query: 539 -SIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDK 597
+I+ S ++ S + G K P + R EK+H R EK + +K+R +
Sbjct: 60 ITIRNSPYRREDSMEDRGEEDDSLAIKP----PQQMSRKEKVHHRKDEKRK---EKRRHR 112
Query: 598 DYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREER 657
+ E K R++E ER +R RE ++ RRE ER + R R
Sbjct: 113 SHSA------EGGKHARVKEKEREHERRKR------HREEQDKARREWERQK--RREMAR 158
Query: 658 ERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIARE-REELRRQQQQL 716
E +RER+RLE +K ERER RE+ + +R + E+ERR E R RE R E+ + +
Sbjct: 159 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTM 218
Query: 717 RYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDF----D 772
R + + H P ++ L D R + +++ +D D
Sbjct: 219 REDYSDKVK------ASHWSRSPPRPPRERFELG-DGRKPVKEEKMEERDLLSDLQDISD 271
Query: 773 HRERGRFPESSAVQS---SSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSD---- 825
+ ESS+ +S S E + + EG + + E+ E + S+
Sbjct: 272 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 331
Query: 826 SRRNEPPPPRNELRESDRRE 845
S ++ E+ E + RE
Sbjct: 332 SEQSAEEVSEEEMSEDEERE 351
Score = 58.2 bits (139), Expect = 4e-08
Identities = 84/401 (20%), Positives = 156/401 (38%), Gaps = 79/401 (19%)
Query: 582 RSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRR---RREIA 638
R +++E+A + + ++ D R + + ++E LR+H R + +R RRE +
Sbjct: 23 RKEQEEKAEIKRLKNSDDRDSKR---DSLEEGELRDH-------RMEITIRNSPYRREDS 72
Query: 639 ERERRERERIRIIREREERERLQRERERLEIERQKLERERMER-ERLERERIRIEQERRK 697
+R E + I+ ++ R ++ R + +R++ R R E + R++ E+ +
Sbjct: 73 MEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVK---EKER 129
Query: 698 EAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGH 757
E ER R REE + +++ +E++KR + R +H R
Sbjct: 130 EHERRKRHREEQDKARRE--WERQKRREMAR----EHSR--------------------- 162
Query: 758 GSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFE 817
R+++R + R+R R + Q E+++R E +K R R
Sbjct: 163 -----RERDRLEQLE-RKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHR 216
Query: 818 RYPKNFSDS------RRNEPPPPRNELRESD-RREVRGERDERRTVIIHDRPDITHPRHP 870
+++SD R+ P PPR D R+ V+ E+ E R ++ D DI+
Sbjct: 217 TMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERD-LLSDLQDISDSERK 275
Query: 871 REAGPNPSRPTSWKSE---------------GSMSTDKRETRVERPERSGREVSGHSVRG 915
+ + S + SE S ++ E E E +G S +
Sbjct: 276 TSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQS 335
Query: 916 APPGNRSSASGYGSREGDRGVIT------DRGGGSQHYPEE 950
A + S RE + ++ DR G EE
Sbjct: 336 AEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 376
Score = 43.9 bits (102), Expect = 8e-04
Identities = 30/136 (22%), Positives = 65/136 (47%), Gaps = 23/136 (16%)
Query: 464 PSKKEMKKENDEKSSSR--SSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKI 521
P K+E +E D S + S ++K +S SS ++ EE+ E+ E++E +++
Sbjct: 251 PVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 310
Query: 522 EGKDEK----------NDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPS 571
E ++E+ N AS Q++E + + E + ++ H++++ ++
Sbjct: 311 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES-------- 362
Query: 572 RRGRYEKIHGRSKEKE 587
R+++ G S+E E
Sbjct: 363 ---RFDRDSGESEEAE 375
Score = 43.5 bits (101), Expect = 0.001
Identities = 63/348 (18%), Positives = 129/348 (37%), Gaps = 58/348 (16%)
Query: 31 KSELKRRNLDITGVKTVLISRLKQAIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKHEAD 90
+ EL+ ++IT + R + ++E+ G + D++ + P ++ ++ + H D
Sbjct: 50 EGELRDHRMEITIRNSPY--RREDSMEDRGEEDDSLAIK-----PPQQMSRKEKVHHRKD 102
Query: 91 ELSGDASVEDDAFIKDCELENQEAHEQDGNDELKDSEEFGENEEENVHSKELLSAE---- 146
E K E +H +G + E+ E+E H +E A
Sbjct: 103 E-------------KRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWE 149
Query: 147 -----ENKRAHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKDIAGS 201
E R H E + +E +E++ +++ Q+ E + E E ++
Sbjct: 150 RQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQ-----REQKERERRAEERRKE 204
Query: 202 GDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAEDDNISVTIQAEDAITLDFDGDD 261
+ +EVS AH H T++E D + + + + +
Sbjct: 205 REARREVS---------------AH-----HRTMREDYSDKVKASHWSRSPPRPPRERFE 244
Query: 262 LLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEA 321
L + K VK E I+ S K S +A G +E+ + E+E
Sbjct: 245 LGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEE----EEEEEEE 300
Query: 322 RESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDK 369
E +E ++E++ ++ TG++ + S + S+ +D+
Sbjct: 301 EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDE 348
Score = 43.5 bits (101), Expect = 0.001
Identities = 39/133 (29%), Positives = 65/133 (48%), Gaps = 19/133 (14%)
Query: 93 SGDASVEDDAFIKDCELENQEAHEQDG--NDELKDSEEFGENEEENVHSKELLSAEENKR 150
S ++S + + E E +E E++G ++E ++ EE E EEE S ++E++
Sbjct: 278 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQS-- 335
Query: 151 AHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSK 210
A E+ E E ED E+E+ E+ + E D GE EE E+++ G+GT
Sbjct: 336 AEEVSEEEMSEDEEREN-ENHLLVVPESRFD----RDSGESEEAEEEV---GEGT----- 382
Query: 211 PLPSEGSLAEADH 223
P +L E D+
Sbjct: 383 --PQSSALTEGDY 393
Score = 37.7 bits (86), Expect = 0.056
Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 11/110 (10%)
Query: 133 EEENVHSKELLS-------AEENKRAHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLT 185
+EE + ++LLS +E + E AE E+E+ E +E E +EG
Sbjct: 253 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEE-EEEEGSTSEESE 311
Query: 186 AQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTV 235
++ EEEE E++ +G ++E S+ E S E E E H V
Sbjct: 312 EEEEEEEEEEEE---TGSNSEEASEQSAEEVSEEEMSEDEERENENHLLV 358
Score = 36.2 bits (82), Expect = 0.16
Identities = 50/242 (20%), Positives = 81/242 (33%), Gaps = 53/242 (21%)
Query: 465 SKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGK 524
+++ ++E D +++ K Q K+ E+R+ E+ +++E++ +
Sbjct: 157 AREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHR 216
Query: 525 DEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSK 584
+ D S+ +K S S+SP RP R R+E GR
Sbjct: 217 TMRED------YSDKVKASH-----WSRSPP-------------RPPRE-RFELGDGRKP 251
Query: 585 EKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRR--------AMELRRRRE 636
KE EKM+E+ L L R + E E
Sbjct: 252 VKE--------------------EKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 291
Query: 637 IAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERR 696
E E E E E E E + E E E E E + E + ++ER
Sbjct: 292 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 351
Query: 697 KE 698
E
Sbjct: 352 NE 353
Score = 30.8 bits (68), Expect = 6.9
Identities = 26/135 (19%), Positives = 55/135 (40%), Gaps = 2/135 (1%)
Query: 117 QDGNDELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQ 176
+D +D++K S EL + + ++ E + + D++ DI E +
Sbjct: 220 EDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ--DISDSERKTS 277
Query: 177 EGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVK 236
E + + EEEE E++ T E S+ E E + ++ E + + +
Sbjct: 278 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 337
Query: 237 EAEDDNISVTIQAED 251
E ++ +S + E+
Sbjct: 338 EVSEEEMSEDEEREN 352
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 85.5 bits (210), Expect = 2e-16
Identities = 113/512 (22%), Positives = 212/512 (41%), Gaps = 93/512 (18%)
Query: 228 EMEAHTTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIA 287
E+E KE E S + ++ DFD DD+L K ++ EA K ++ +A
Sbjct: 25 EIEGAGAAKEQEPQK-SKGKKKKEKKKQDFDEDDIL---KELEELSLEAQGIKADRETVA 80
Query: 288 QSP----EKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAE--------SGDKEK 335
P E+E + + GKK+ D E E ++S K SG +
Sbjct: 81 VKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDD 140
Query: 336 DTLKKGPSSTGASGQAKSSSKE----SKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGL 391
D K P A G+A+ S+K+ +D S K + S ++SG SG + S
Sbjct: 141 DDFNKLPKK--AKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQS-- 196
Query: 392 SSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRTELH 451
+ KN K G + + G +S ++
Sbjct: 197 ----RKGQKKNQKNKPGPNIES--------------GNEDDDASFKIK------------ 226
Query: 452 GQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSE 511
+V + K + ++E KK ++EK+ R +K+ + K Q+ K+ +++ E++
Sbjct: 227 ----TVAQKKAEKKERERKKRDEEKAKLRKLKEKEEL-ETGKKDQSKQKESQRKFEEETV 281
Query: 512 K-KESKDTKKIEGKDEKNDNGASGQT-SESIKKSEEKKRISSKSPGHMVILDQTKGDHCR 569
K K + DT I +EK + + + +E KK ++KK+
Sbjct: 282 KSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKK--------------------- 320
Query: 570 PSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAM 629
++G E+ KEKE+ K ++ + ++ +E++ RE R +RL
Sbjct: 321 --KKGEKEE-----KEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELE 373
Query: 630 ELRRRREIAERERRERERIRIIREREERERLQRERERL-EIERQKLERERMERERLERER 688
R+ E E+E+RER++ + E+E +ERL++E + L + +R+ R + L+ +
Sbjct: 374 AKRKEEERLEQEKRERKKQK---EKERKERLKKEGKLLTKSQREARARAEATLKLLQAQG 430
Query: 689 IRIEQERRKEAERIAREREELRRQQQQLRYEQ 720
+ + + +R E ++ ++ QQL ++
Sbjct: 431 VEVPSKDSLPKKRPIYEDKKRKKIPQQLESKE 462
Score = 74.7 bits (182), Expect = 4e-13
Identities = 67/317 (21%), Positives = 143/317 (45%), Gaps = 29/317 (9%)
Query: 458 EKVKGDPSKKEMKKEND-EKSSSRSSGDKKNTSDRSSKTQAS--------VKKEEKRSSE 508
+K KG KK+ +ND E+ + S KK + S + K+ K ++
Sbjct: 96 KKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQ 155
Query: 509 KSEKK------ESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKS-PGHMVILD 561
KS KK + ++KKI+ + N +G SG S+ +S + ++ + K+ PG +
Sbjct: 156 KSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESG 215
Query: 562 QTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVR 621
D + +K + +E+++ +K + + + KE L K + + +E +
Sbjct: 216 NEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRK 275
Query: 622 FERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERME- 680
FE ++ + + E + E ++ ++++++ + E+++ E+E+ +
Sbjct: 276 FEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKG 335
Query: 681 ---------RERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRD 731
+E L + + E+++R+E ERI R E +++++ R EQEKR +R +
Sbjct: 336 PSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKR---ERKKQ 392
Query: 732 VDHRRDDPYWSENKKLS 748
+ R + E K L+
Sbjct: 393 KEKERKERLKKEGKLLT 409
Score = 59.7 bits (143), Expect = 1e-08
Identities = 118/563 (20%), Positives = 212/563 (37%), Gaps = 83/563 (14%)
Query: 53 KQAIEEEGGDPDNIELTVSTDTPNKKP--TKGKGKKHEADELSGDASVEDDAFIKDCELE 110
K +E G D+ D NK P KGK +K + ++ IK+
Sbjct: 128 KPKVEMYSGSDDD-------DDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRI 180
Query: 111 NQEAHEQDGNDELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIES 170
N D +DE S + + ++N + S E+ A + I+ + ++ E
Sbjct: 181 NSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDA-----SFKIKTVAQKKAEK 235
Query: 171 QEIEAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEME 230
+E E ++ +++ + E+EE E G ++ SK S+ E T ++
Sbjct: 236 KERERKKRDEEKAKLRKLKEKEELE-------TGKKDQSKQKESQRKFEE--ETVKSKVT 286
Query: 231 AHTTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSP 290
T V A ++ AED D+E K K +D +
Sbjct: 287 VDTGVIPASEEKAETPTAAED---------------------DNEGDKKK--KDKKKKKG 323
Query: 291 EKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDK--EKDTLKKGPSSTGAS 348
EKE K+ E K G + VK +EA K+ E K E++ +K+
Sbjct: 324 EKEEKEKE----KKKGPSKATVK---AMQEALAKLKEEEERQKREEEERIKRLEELEAKR 376
Query: 349 GQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYG 408
+ + +E ++ K + ++ G K + S + +A L G
Sbjct: 377 KEEERLEQEKRERKKQKEKERKERLKKEG------KLLTKSQREARARAEATLKLLQAQG 430
Query: 409 KVLSAKVVTNARSP---GAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPS 465
+ +K + P K I S EVS + E+ Q V + + P
Sbjct: 431 VEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQ--GVPEKEETPP 488
Query: 466 KKEMKKENDEKSSSRSSGDKKNTSDRSSKTQAS-VKKEEKRSSEKSEKKESKDTKKIEGK 524
E ++E D + + + + + + K + + V E K + E+ E++E ++ + E +
Sbjct: 489 PVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESE 548
Query: 525 DEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRR----GRYEKIH 580
+E+ + G SE + EE +++S + D K +PS+ Y+
Sbjct: 549 EEEEEEG----ESEGSEGDEEDEKVSDEK-------DSGKTLDKKPSKEMSSDSEYDSDD 597
Query: 581 GRSKEKERASLDKKRDKDYRRKE 603
R+KE ERA KR + RR E
Sbjct: 598 DRTKE-ERAYDKAKRRIEKRRLE 619
Score = 56.2 bits (134), Expect = 2e-07
Identities = 82/394 (20%), Positives = 168/394 (42%), Gaps = 50/394 (12%)
Query: 8 VAASAASGQAEGKKITDLRVIDLKSELKRRNLDITGVKTVLISRLKQAIEEEGGDPDNIE 67
VA A + +K D L+ ++ L+ TG K + KQ + + + ++
Sbjct: 228 VAQKKAEKKERERKKRDEEKAKLRKLKEKEELE-TGKK----DQSKQKESQRKFEEETVK 282
Query: 68 LTVSTDTPNKKPTKGKGKKHEA--DELSGDASVEDDAFIKDCELENQEAHEQDGNDE--- 122
V+ DT ++ K + A D+ GD +D K E E +E ++ G +
Sbjct: 283 SKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKG-EKEEKEKEKKKGPSKATV 341
Query: 123 ---------LKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIESQEI 173
LK+ EE + EEE K L E ++ E +E E E ++++ E +E
Sbjct: 342 KAMQEALAKLKEEEERQKREEEE-RIKRLEELEAKRKEEERLEQEKRERKKQKEKERKER 400
Query: 174 EAQEGEDDTFLTAQDGEEEENEKDIAGSGDGT----QEVSKPLPSEGSLAEADHTAHEEM 229
+EG+ LT +++++ + T Q +PS+ SL + +E+
Sbjct: 401 LKKEGK---LLT-------KSQREARARAEATLKLLQAQGVEVPSKDSLPKK-RPIYEDK 449
Query: 230 EAHTTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQS 289
+ ++ E +S +++ A+ +++E G K +P++ +D +
Sbjct: 450 KRKKIPQQLESKEVSESMELCAAV-------EVMEQGVPEKEETPPPVEPEEEED----T 498
Query: 290 PEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASG 349
+ D+E A+ ++ +K V+G+ V E +E+ ++ E ++E++ ++ G
Sbjct: 499 EDAGLDDWEAMASDEETEK---VEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEG 555
Query: 350 QAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSST 383
+++ S + +D K S + D G T S S+
Sbjct: 556 ESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSS 589
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 84.7 bits (208), Expect = 4e-16
Identities = 74/278 (26%), Positives = 140/278 (50%), Gaps = 36/278 (12%)
Query: 459 KVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDT 518
+++ D ++ E E +EKS SR + ++ +K S +K + R +E+++K+ D
Sbjct: 136 RMQNDTAENETT-EKEEKSESRQERYEIEETETVTK---SYQKNDWRDAEENKKE---DK 188
Query: 519 KKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEK 578
+K E ++EK G+ G+ + E+ +++S V++ G + E+
Sbjct: 189 EKEEEEEEKPKRGSIGENQVEVMVEEK----TTESQEETVVMSLKNGQISSEEPKQEEER 244
Query: 579 IHG----------RSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRA 628
G ++KERA ++ R + R+ I + +++++ + R E +A
Sbjct: 245 EQGSDEISHHEKMEEEDKERAEAERARLEAEERERI---KAEQDKKIADERARIEAEEKA 301
Query: 629 M-ELRRRREIAERER-RERERIRIIREREERERLQRERERLEIERQKLERERMERERLER 686
+ R RRE ERER RE E+ R EER+R++ E +R ERQ+++ E +R
Sbjct: 302 AAQERERREAEERERMREEEK----RAAEERQRIKEEEKRAAEERQRIKEEE---KRAAE 354
Query: 687 ERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRN 724
ER RI++E ++ AE R R E ++++ + E++KRN
Sbjct: 355 ERQRIKEEEKRAAEERQRARAE---EEEKAKVEEQKRN 389
Score = 79.3 bits (194), Expect = 2e-14
Identities = 138/732 (18%), Positives = 286/732 (39%), Gaps = 130/732 (17%)
Query: 162 DIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEA 221
++ ++ E +EA+ + Q +++E E QE + E SL +
Sbjct: 9 ELRRQKREEMRLEAER------IAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQV 62
Query: 222 DHTAHEEMEAHTTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKD 281
T E+ A +V + E + Q E GDD E ++ E + K
Sbjct: 63 --TDQVEVNAQNSVPDEEAKTTTTNTQVE--------GDD--EAAFLERLARREERRQKR 110
Query: 282 GQDAIAQSPEKESKDYEMNANHKDGKKE-DCVKGDPVEKEARESSKKAESGDKEKDTLKK 340
Q+A+ + E + + + + + + D + + EKE + S++ +E +T+ K
Sbjct: 111 LQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTK 170
Query: 341 GPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSN----TK 396
A+ + KE K+ K+++ GS G + + V ++ T
Sbjct: 171 SYQKNDWR-DAEENKKEDKE-----KEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETV 224
Query: 397 AADLKNLFGKYGKVLSAKVVTNA-RSPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLI 455
LKN G++ S + R G+ + R A R E +
Sbjct: 225 VMSLKN-----GQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEER-- 277
Query: 456 SVEKVKGDPSKK----EMKKENDEKSSSRSSGDK--------KNTSDRSSKTQASVKKEE 503
E++K + KK + E +EK++++ + + R+++ + +K+EE
Sbjct: 278 --ERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEE 335
Query: 504 KRSSEK------SEKKESKDTKKIEGKDEK---NDNGASGQTSESIKKSEEKKRISSKSP 554
KR++E+ EK+ +++ ++I+ ++++ A + E K E+K+ +
Sbjct: 336 KRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEK 395
Query: 555 GHMVILDQTKGDHCRPSRRGRY--EK----------IHGRSKEKERASLDKKRDKDYRRK 602
H + + KG+ G++ EK + + E++ + KR+K K
Sbjct: 396 KHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDK 455
Query: 603 EILPFEKMKEQRLREHLVRFERLRRAMELRR----------------------------- 633
E++K++++++ E ++ M+ ++
Sbjct: 456 PTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGG 515
Query: 634 RREIAERERRERERIRIIREREERERLQRERERLEIERQK-------LERERMERERLER 686
R + +E ++ + EE R + E E E E+ K LE E ++++R ER
Sbjct: 516 RASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREER 575
Query: 687 ERIRIEQERRK---EAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDP---- 739
++ E+E+R+ EA+R RE EE RR ++++ + + ++ D DD
Sbjct: 576 RKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFK 635
Query: 740 -YWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERG-RFPESSAVQSSSFERRDRFV 797
+ + L ++ A F N + G + +A+ S R +++
Sbjct: 636 CFTPKGSSLKIEERAEF------------LNKSVQKSSGVKSTHQAAIVSKIDSRLEQYT 683
Query: 798 GQSEG-KKARPT 808
EG K A+PT
Sbjct: 684 SAIEGTKSAKPT 695
Score = 64.7 bits (156), Expect = 4e-10
Identities = 129/667 (19%), Positives = 238/667 (35%), Gaps = 123/667 (18%)
Query: 51 RLKQAIEEE--GGDPDNIELTVSTDTPNKKP-TKGKGKKHEADELSG------------- 94
RL+Q EEE G D +E+ P+++ T + E D+ +
Sbjct: 49 RLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQ 108
Query: 95 -------DASVEDDAFIKDCELE--NQEAHEQDGNDELKDSEEFGENEEENVHSKELLSA 145
+ E D I D L ++ +E + EE E+ +E +E +
Sbjct: 109 KRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETV 168
Query: 146 EENKRAHELIEAEGIEDIEKEDIESQEIEAQE------GEDDTFLTAQDGEEEENEKDIA 199
++ + ++ +A E+ +KED E +E E ++ GE+ + ++ E E+ +
Sbjct: 169 TKSYQKNDWRDA---EENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVV 225
Query: 200 GS-GDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAEDDNISVTIQAEDAITLDFD 258
S +G +P E +D +H E + AE + + + + I + D
Sbjct: 226 MSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQD 285
Query: 259 GDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVE 318
KI D A + + A + +E+++ E + E+ + E
Sbjct: 286 ----------KKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEE 335
Query: 319 KEARESSKKAESGDK----EKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSS 374
K A E ++ + +K E+ +K+ Q + +E K K +K
Sbjct: 336 KRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEK 395
Query: 375 TSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKCYGIVTMSS 434
+ K K + + K V ++ K V
Sbjct: 396 KHAMQETKIKG-------------------EKVEQKIEGKWVNEKKAQEDKLQTAVLKKQ 436
Query: 435 STEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKE--NDEKSSSRSSGDKKNTSDRS 492
E G + ++ K K KKE DEK
Sbjct: 437 GEE-------------KGTKVQAKREKLQEDKPTFKKEEIKDEK---------------- 467
Query: 493 SKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSK 552
+KK+++ K E K D KK + K+ NG + +K +E +
Sbjct: 468 ------IKKDKE---PKEEVKSFMDRKK-GFTEVKSQNGEF--MTHKLKHTEN----TFS 511
Query: 553 SPGHMVILDQTKGDHCRPSRRG-RYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMK 611
PG +D + + G R E++ R E E +K + K +++ L E++K
Sbjct: 512 RPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQK--QQEAALELEELK 569
Query: 612 EQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIER 671
++R V E E RR++E A+R+ RE E R ++E ER R + +R ++
Sbjct: 570 KKREERRKVLEEE-----EQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPE 624
Query: 672 QKLERER 678
L ++
Sbjct: 625 DGLSDDK 631
Score = 57.0 bits (136), Expect = 9e-08
Identities = 122/566 (21%), Positives = 213/566 (37%), Gaps = 108/566 (19%)
Query: 31 KSELKRRNLDITGVKTVLISRLKQAIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKHEAD 90
KSE ++ +I +TV S K + + + E + +KP +G +++ +
Sbjct: 152 KSESRQERYEIEETETVTKSYQKN--DWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVE 209
Query: 91 ELSGDASVEDDAFIKDCELEN---------QEAHEQDGNDELKDSEEFGENEEENVHSKE 141
+ + + E L+N QE + G+DE+ E+ E ++E ++
Sbjct: 210 VMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAER 269
Query: 142 L-LSAEENKRAHELIEAEGIEDI--EKEDIESQE-IEAQEGEDDTFLTAQDGEEEENEKD 197
L AEE +R I+AE + I E+ IE++E AQE E ++ EE E +
Sbjct: 270 ARLEAEERER----IKAEQDKKIADERARIEAEEKAAAQERE------RREAEERERMR- 318
Query: 198 IAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAEDDNISVTIQAEDAITLDF 257
+E + + E + A EE + +KE E AE+
Sbjct: 319 --------EEEKRAAEERQRIKEEEKRAAEERQ---RIKEEEKR------AAEE------ 355
Query: 258 DGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEK----ESKDYEMNANHKDGKKEDCVK 313
+I + E ++ Q A A+ EK E K + K +E +K
Sbjct: 356 ----------RQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIK 405
Query: 314 GDPVEKEAR---ESSKKAESGDKEKDTLKKGPSSTGASGQAKS----------SSKESKD 360
G+ VE++ + KKA+ + LKK G QAK +E KD
Sbjct: 406 GEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKD 465
Query: 361 SK-TSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNA 419
K K+ K S T+ +G K +N F + G S V
Sbjct: 466 EKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRAS---VDTK 522
Query: 420 RSPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSK-----KEMKKEND 474
+ GA E + + L R + EK+K + +E+KK+ +
Sbjct: 523 EAEGA---------PQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKRE 573
Query: 475 EK------SSSRSSGDKKNTSDRSSKTQASVKKE-EKRSSEKSEKKE-------SKDTKK 520
E+ R ++ + R + + +K+E E+R +E +EK++ S D K
Sbjct: 574 ERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKP 633
Query: 521 IEGKDEKNDNGASGQTSESIKKSEEK 546
+ K + + +E + KS +K
Sbjct: 634 FKCFTPKGSSLKIEERAEFLNKSVQK 659
Score = 41.2 bits (95), Expect = 0.005
Identities = 56/253 (22%), Positives = 103/253 (40%), Gaps = 17/253 (6%)
Query: 671 RQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPR 730
R++L R++ E RLE ERI ++ E E ARER R +Q++LR +QE+ + +
Sbjct: 7 RRELRRQKREEMRLEAERIAYQRNDDDE-EEAARERRR-RARQERLRQKQEEESLGQVTD 64
Query: 731 DVDHRRDDPYWSE-------NKKLSLDTDARFGH--GSDYSRQQNRFNDFDHRERGRFPE 781
V+ + E N ++ D +A F R+Q R + R++ P
Sbjct: 65 QVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPT 124
Query: 782 SSAVQSSSFERR---DRFVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNEL 838
+ S RR D ++ K+ + +R+E E ++N+
Sbjct: 125 ITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENK 184
Query: 839 RESDRREVRGERDERRTVIIHDRPDITHPRHPREAGPNPSRPTSWKSEGSMSTDKRETRV 898
+E +E E +R I ++ ++ E+ G +S+++ +
Sbjct: 185 KEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTES--QEETVVMSLKNGQISSEEPKQEE 242
Query: 899 ERPERSGREVSGH 911
ER E+ E+S H
Sbjct: 243 ER-EQGSDEISHH 254
Score = 38.1 bits (87), Expect = 0.043
Identities = 67/349 (19%), Positives = 131/349 (37%), Gaps = 74/349 (21%)
Query: 622 FERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMER 681
FER R ELRR++ E R E ERI R ++ E RER R RQ+ R++ E
Sbjct: 4 FERRR---ELRRQKR--EEMRLEAERIAYQRNDDDEEEAARERRRRA--RQERLRQKQEE 56
Query: 682 ERL-------------------------------ERERIRIEQERRKEAERIAREREELR 710
E L + E +E+ R+E R R +E L
Sbjct: 57 ESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALE 116
Query: 711 RQQQ---------------QLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARF 755
RQ++ +++ + + + ++ + R++ E + ++
Sbjct: 117 RQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKND 176
Query: 756 GHGSDYSRQQNRFNDFDHRE---RGRFPESSA---VQSSSFERRDRFV------GQSEGK 803
++ ++++++ + + E RG E+ V+ + E ++ V GQ +
Sbjct: 177 WRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSE 236
Query: 804 KARPTARREDPSFE-RYPKNFSDSRRNEPPPPRNELRESDRREVRGERDER----RTVII 858
+ + RE S E + + + + R L +R ++ E+D++ R I
Sbjct: 237 EPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIE 296
Query: 859 HDRPDITHPRHPREAGPNPSRPTSWKSEGSMSTDKRETRVERPERSGRE 907
+ R REA + E + ++R+ E +R+ E
Sbjct: 297 AEEKAAAQERERREA----EERERMREEEKRAAEERQRIKEEEKRAAEE 341
Score = 38.1 bits (87), Expect = 0.043
Identities = 73/411 (17%), Positives = 154/411 (37%), Gaps = 43/411 (10%)
Query: 503 EKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKK---RISSKSPGHMVI 559
E+R + +K+E + ++ND+ E +++ +++ + +S G +
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTD 64
Query: 560 LDQTKGDHCRPSRRGRYEKIHGRSK-EKERASLDKKRDKDYRRKEILPFEKMKEQRLREH 618
+ + P + + + + + E A L++ ++ RR++ L E ++ Q+ +
Sbjct: 65 QVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQ-EALERQKEFDP 123
Query: 619 LVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIER-QKLERE 677
+ L R + + AE E E+E E+ + +ER EIE + + +
Sbjct: 124 TITDASLSLPSR-RMQNDTAENETTEKE-----------EKSESRQERYEIEETETVTKS 171
Query: 678 RMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRD 737
+ + + E + E + ++E E +R + Q ++ E EK + V ++
Sbjct: 172 YQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVE-EKTTESQEETVVMSLKN 230
Query: 738 DPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFV 797
SE K + + S + + + + ER R E R+R
Sbjct: 231 GQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARL---------EAEERERIK 281
Query: 798 GQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRESDRREV----RGERDER 853
+ + K A AR E K + R R +RE ++R R + +E+
Sbjct: 282 AEQDKKIADERAR-----IEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEK 336
Query: 854 RTVIIHDRPDITHPRHPREAGPNPSRPTSWKSEGSMSTDKRETRVERPERS 904
R R R E R + E + +++ R E E++
Sbjct: 337 RAAEERQRIKEEEKRAAEE------RQRIKEEEKRAAEERQRARAEEEEKA 381
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 84.0 bits (206), Expect = 7e-16
Identities = 117/472 (24%), Positives = 188/472 (39%), Gaps = 82/472 (17%)
Query: 507 SEKSEKKESKD----TKKIEGKDEKNDNGASGQTSESIKKSEEKKRISS--KSPGHMVIL 560
+E+ + + KD T+K G+ ++ + SG E + E++ SS PG +
Sbjct: 294 NERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTL- 352
Query: 561 DQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLV 620
R + ++ +KE+ A +R + + +++ E+ K Q L E
Sbjct: 353 ------------RRDFLRLQQENKERSEAL---RRQQLLQEQQLREQEEYKRQLLAERQK 397
Query: 621 RFERL---RRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERE 677
R E+ RR +E ++RRE R ++ERE+ R RE+EE+ RL+ E+ER++ E E
Sbjct: 398 RIEQQKEQRRRLEEQQRREREARRQQEREQRR--REQEEKRRLE------ELERRRKEEE 449
Query: 678 RMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEK-RNSLKRPRDVDHRR 736
ER R E E+ R+E+E+ ++ E+ L QQQL EQ + +RP ++
Sbjct: 450 --ERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLHDHRRPHPQHSQQ 507
Query: 737 DDPYWSENKKLSLDTDARFGH--GSDYSRQ-QNRFNDFDHRERGRFPESSAVQSSSFERR 793
P E K S H +D +R+ ++RF +H PE+ + Q+
Sbjct: 508 PPPPQQERSKPSFHAPEPKAHYEPADRAREVEDRFRKTNHSS----PEAQSKQT------ 557
Query: 794 DRFVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRESDRREVRGERDER 853
G+ P SF P P+ +R + R V RD
Sbjct: 558 --------GRVLEPPVPSRSESFSNGNSESVHPALQRPAEPQVPVRTTSRSPVLSRRDSP 609
Query: 854 RTVIIHDRPDITHPRHPREAGPNPSRPTSWKSEGSMSTDKRETRVER--PERSGREVSGH 911
+ +G S+ S S+ RVE+ P SG
Sbjct: 610 L----------------QGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSSGS 653
Query: 912 SVRGAPPGNR-SSASGYGSREGDRGVITDRGGGSQHY------PEERHVVER 956
S G+ PG+ S SG G R R G SQ PE++ V R
Sbjct: 654 SNSGSQPGSHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFR 705
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 83.6 bits (205), Expect = 9e-16
Identities = 87/421 (20%), Positives = 191/421 (45%), Gaps = 57/421 (13%)
Query: 453 QLISVEKVKGDPSKKEMKKENDE------KSSSRSSGDK--KNTSDRSSKTQASVKKEE- 503
QL+ EK + + KE+K++ + + ++ D K S+K QA V++ E
Sbjct: 231 QLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENEL 290
Query: 504 -KRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQ 562
R +++ E+K + +KI+ +EK + E I++ EEK R +
Sbjct: 291 WNRLNQQQEEKMWRQEEKIQEWEEKIQ-----EQEEKIREQEEKIREQEE---------- 335
Query: 563 TKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRF 622
+ R E++ +EK R + +K+ + + + KE+++RE
Sbjct: 336 ---------KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRE----- 381
Query: 623 ERLRRAMELRRRREIAERERRERERIRIIREREERE-RLQRERERLEIERQKLERE---- 677
L M + + E +R+E E+IR +R+E+E ++ R+ E++ + +K+ +
Sbjct: 382 --LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKM 439
Query: 678 -RMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRR 736
R E + E+E+IR E+E+R+E E + R+ E++R Q++ R ++EK + ++ R ++
Sbjct: 440 WRQEEKIHEQEKIR-EEEKRQEQEEMWRQEEKIREQEEIWR-QKEKMHEQEKIR----KQ 493
Query: 737 DDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRF 796
++ W + +K+ + RQ+ + + + + R + + + E+ ++
Sbjct: 494 EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKM 553
Query: 797 VGQSEGKKARPTARREDPSFERYPKNFSDS----RRNEPPPPRNELRESDRREVRGERDE 852
Q E + + RR++ + + R E E + ++ E+ E++E
Sbjct: 554 GEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEE 613
Query: 853 R 853
+
Sbjct: 614 K 614
Score = 79.3 bits (194), Expect = 2e-14
Identities = 68/288 (23%), Positives = 146/288 (50%), Gaps = 13/288 (4%)
Query: 458 EKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKD 517
EK++ K +++ E+ R +K ++ + +A + ++E++ E+ EK ++
Sbjct: 377 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 436
Query: 518 TKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYE 577
KK+ ++EK + E ++ EE R K I Q + H + R + E
Sbjct: 437 -KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEE 495
Query: 578 KIHGRSKEKERASLDKKRDKD---YRRKEILPFEKMK----EQRLREHLVRFERLRRAM- 629
K+ R +EK +K R+++ +R++E + ++ K E+++RE + M
Sbjct: 496 KVW-RQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMG 554
Query: 630 ELRRRREIAERERRERERIRIIRE--REERERLQRERERLEIERQKLERERMERERLERE 687
E + + E+ RR+ E+IR E RE++E+++ + E++ + +K+ RE+ E + + E
Sbjct: 555 EQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKI-REQEEMMQEQEE 613
Query: 688 RIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHR 735
++ ++E+ E E +E+EE R+Q++ +EQE R + + +H+
Sbjct: 614 KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQ 661
Score = 68.2 bits (165), Expect = 4e-11
Identities = 67/305 (21%), Positives = 151/305 (49%), Gaps = 29/305 (9%)
Query: 455 ISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKE 514
++ +K K D +E+ KE D S +NT + + K +EK +SEK E
Sbjct: 184 VATQKKKADRYIEELTKERDALSLELY----RNTITDEELKEKNAKLQEKLQLVESEKSE 239
Query: 515 SK-DTKKIEGKDEKNDNGASGQT--SESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPS 571
+ + K+++ K E+ Q +E+ +E + +S+K + Q + +
Sbjct: 240 IQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK------LQAQVEENELWNR 293
Query: 572 RRGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAM-- 629
+ E+ R +EK + +K ++++ + +E +E+++RE + R M
Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE-------QEEKIREQEEKMRRQEEMMWE 346
Query: 630 ---ELRRRREIA-ERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLE 685
++RR+ E+ E+E + R ++ E+EE+ R E+ + + ++ E +R E E++
Sbjct: 347 KEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR 406
Query: 686 RERIRIEQERR--KEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRD-DPYWS 742
+ R EQE + ++ E+I + E++R Q++++ ++EK + ++ R+ + R++ + W
Sbjct: 407 EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR 466
Query: 743 ENKKL 747
+ +K+
Sbjct: 467 QEEKI 471
Score = 33.5 bits (75), Expect = 1.1
Identities = 49/302 (16%), Positives = 128/302 (42%), Gaps = 18/302 (5%)
Query: 31 KSELKRRNLDITGVKTVLISRLKQAIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKHEAD 90
K E RR ++ K + RL++ + E+ +E + +K + + K+ E +
Sbjct: 347 KEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQ---EKIREQEEKRQEEE 403
Query: 91 ELSGDASVEDDAFIKDCELENQEAHEQDGNDELKDSEEFGENEEENVHSKELLSAEENKR 150
++ ++ ++ ++ QE ++ +++++ E+ +EE +H +E + EE ++
Sbjct: 404 KIREQEKRQE----QEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQ 459
Query: 151 AHELIEAEGIEDIEKEDIESQEIEAQEGE-----DDTFLTAQDGEEEENEKDIAGSGDGT 205
E + + + E+E+I Q+ + E E ++ ++ ++ EK
Sbjct: 460 EQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMW 519
Query: 206 QEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAEDDNISVTIQAEDAITLDFDGDDLLET 265
++ K E + E + E+ E ++E E+ + ++ + + + E
Sbjct: 520 RQEEKIREQEEKIREQEEKIREQEE---MMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQ 576
Query: 266 GKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESS 325
+ ++ + K ++ ++ I + EK + EM ++ E K E++ +E
Sbjct: 577 EEKIR---EQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 633
Query: 326 KK 327
+K
Sbjct: 634 EK 635
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 83.6 bits (205), Expect = 9e-16
Identities = 98/380 (25%), Positives = 158/380 (41%), Gaps = 59/380 (15%)
Query: 483 GDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSE---- 538
GD+K++ KT + +E+KR E+ EK E K K + +D K D+ G+ +
Sbjct: 2 GDEKDSW--KVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCME 59
Query: 539 -SIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDK 597
+I+ S ++ S + G K P + R EK+H R EK +
Sbjct: 60 ITIRNSPYRREDSMEDRGEEDDSLAIKP----PQQMSRKEKVHHRKDEKRK--------- 106
Query: 598 DYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREER 657
EK K R++E E RR +R RE ++ RRE ER + R R
Sbjct: 107 ----------EKWKHARVKER----EHERR----KRHREEQDKARREWERQK--RREMAR 146
Query: 658 ERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIARE-REELRRQQQQL 716
E +RER+RLE +K ERER RE+ + +R + E+ERR E R RE R E+ + +
Sbjct: 147 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTM 206
Query: 717 RYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDF----D 772
R + + H P ++ L D R + +++ +D D
Sbjct: 207 REDYSDKVK------ASHWSRSPPRPPRERFELG-DGRKPVKEEKMEERDLLSDLQDISD 259
Query: 773 HRERGRFPESSAVQS---SSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSD---- 825
+ ESS+ +S S E + + EG + + E+ E + S+
Sbjct: 260 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 319
Query: 826 SRRNEPPPPRNELRESDRRE 845
S ++ E+ E + RE
Sbjct: 320 SEQSAEEVSEEEMSEDEERE 339
Score = 52.8 bits (125), Expect = 2e-06
Identities = 82/397 (20%), Positives = 152/397 (38%), Gaps = 83/397 (20%)
Query: 582 RSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERE 641
R +++E+A + + ++ D R + + ++E LR+H + +R + RRE + +
Sbjct: 23 RKEQEEKAEIKRLKNSDDRDSKR---DSLEEGELRDHCMEIT-IRNSPY---RREDSMED 75
Query: 642 RRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAER 701
R E + I+ ++ R ++ R + +R++ + +ER E ERRK
Sbjct: 76 RGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKER--------EHERRK---- 123
Query: 702 IAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDY 761
R REE + +++ +E++KR + R +H R
Sbjct: 124 --RHREEQDKARRE--WERQKRREMAR----EHSR------------------------- 150
Query: 762 SRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERYPK 821
R+++R + R+R R + Q E+++R E +K R R +
Sbjct: 151 -RERDRLEQLE-RKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRE 208
Query: 822 NFSDS------RRNEPPPPRNELRESD-RREVRGERDERRTVIIHDRPDITHPRHPREAG 874
++SD R+ P PPR D R+ V+ E+ E R ++ D DI+ +
Sbjct: 209 DYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERD-LLSDLQDISDSERKTSSA 267
Query: 875 PNPSRPTSWKSE---------------GSMSTDKRETRVERPERSGREVSGHSVRGAPPG 919
+ S + SE S ++ E E E +G S + A
Sbjct: 268 ESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEV 327
Query: 920 NRSSASGYGSREGDRGVIT------DRGGGSQHYPEE 950
+ S RE + ++ DR G EE
Sbjct: 328 SEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 364
Score = 44.7 bits (104), Expect = 5e-04
Identities = 46/225 (20%), Positives = 99/225 (44%), Gaps = 42/225 (18%)
Query: 464 PSKKEMKKENDEKSSSR--SSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKI 521
P K+E +E D S + S ++K +S SS ++ EE+ E+ E++E +++
Sbjct: 239 PVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 298
Query: 522 EGKDEK----------NDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPS 571
E ++E+ N AS Q++E + + E + ++ H++++ ++
Sbjct: 299 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES-------- 350
Query: 572 RRGRYEKIHGRSKEKE--------RASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFE 623
R+++ G S+E E ++S + D +LP E +Q L ++L +
Sbjct: 351 ---RFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIE--LKQELPKYLPALQ 405
Query: 624 RLRRAMELRRRREIAE---------RERRERERIRIIREREERER 659
R E + I E ++++ E + + R + E+E+
Sbjct: 406 GCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEK 450
Score = 43.5 bits (101), Expect = 0.001
Identities = 39/133 (29%), Positives = 65/133 (48%), Gaps = 19/133 (14%)
Query: 93 SGDASVEDDAFIKDCELENQEAHEQDG--NDELKDSEEFGENEEENVHSKELLSAEENKR 150
S ++S + + E E +E E++G ++E ++ EE E EEE S ++E++
Sbjct: 266 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQS-- 323
Query: 151 AHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSK 210
A E+ E E ED E+E+ E+ + E D GE EE E+++ G+GT
Sbjct: 324 AEEVSEEEMSEDEEREN-ENHLLVVPESRFD----RDSGESEEAEEEV---GEGT----- 370
Query: 211 PLPSEGSLAEADH 223
P +L E D+
Sbjct: 371 --PQSSALTEGDY 381
Score = 39.3 bits (90), Expect = 0.019
Identities = 55/319 (17%), Positives = 121/319 (37%), Gaps = 50/319 (15%)
Query: 51 RLKQAIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFIKDCELE 110
R + ++E+ G + D++ + P ++ ++ + H DE + A +K+ E E
Sbjct: 68 RREDSMEDRGEEDDSLAIK-----PPQQMSRKEKVHHRKDEKRKEKWKH--ARVKEREHE 120
Query: 111 NQEAHEQDGNDELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIES 170
++ H ++ + ++ E E HS+ E + +E +E++
Sbjct: 121 RRKRHREEQDKARREWERQKRREMAREHSRR--------------ERDRLEQLERKRERE 166
Query: 171 QEIEAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEME 230
+++ Q+ E + E E ++ + +EVS AH
Sbjct: 167 RKMREQQKEQ-----REQKERERRAEERRKEREARREVS---------------AH---- 202
Query: 231 AHTTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSP 290
H T++E D + + + + +L + K VK E I+ S
Sbjct: 203 -HRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSE 261
Query: 291 EKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQ 350
K S +A G +E+ + E+E E +E ++E++ ++ TG++ +
Sbjct: 262 RKTSSAESSSAESGSGSEEE----EEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE 317
Query: 351 AKSSSKESKDSKTSSKDDK 369
S + S+ +D+
Sbjct: 318 EASEQSAEEVSEEEMSEDE 336
Score = 37.7 bits (86), Expect = 0.056
Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 11/110 (10%)
Query: 133 EEENVHSKELLS-------AEENKRAHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLT 185
+EE + ++LLS +E + E AE E+E+ E +E E +EG
Sbjct: 241 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEE-EEEEGSTSEESE 299
Query: 186 AQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTV 235
++ EEEE E++ +G ++E S+ E S E E E H V
Sbjct: 300 EEEEEEEEEEEE---TGSNSEEASEQSAEEVSEEEMSEDEERENENHLLV 346
Score = 36.2 bits (82), Expect = 0.16
Identities = 50/242 (20%), Positives = 81/242 (33%), Gaps = 53/242 (21%)
Query: 465 SKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGK 524
+++ ++E D +++ K Q K+ E+R+ E+ +++E++ +
Sbjct: 145 AREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHR 204
Query: 525 DEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSK 584
+ D S+ +K S S+SP RP R R+E GR
Sbjct: 205 TMRED------YSDKVKASH-----WSRSPP-------------RPPRE-RFELGDGRKP 239
Query: 585 EKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRR--------AMELRRRRE 636
KE EKM+E+ L L R + E E
Sbjct: 240 VKE--------------------EKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 279
Query: 637 IAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERR 696
E E E E E E E + E E E E E + E + ++ER
Sbjct: 280 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 339
Query: 697 KE 698
E
Sbjct: 340 NE 341
Score = 30.8 bits (68), Expect = 6.9
Identities = 26/135 (19%), Positives = 55/135 (40%), Gaps = 2/135 (1%)
Query: 117 QDGNDELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQ 176
+D +D++K S EL + + ++ E + + D++ DI E +
Sbjct: 208 EDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ--DISDSERKTS 265
Query: 177 EGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVK 236
E + + EEEE E++ T E S+ E E + ++ E + + +
Sbjct: 266 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 325
Query: 237 EAEDDNISVTIQAED 251
E ++ +S + E+
Sbjct: 326 EVSEEEMSEDEEREN 340
>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
Length = 1235
Score = 83.6 bits (205), Expect = 9e-16
Identities = 156/812 (19%), Positives = 322/812 (39%), Gaps = 97/812 (11%)
Query: 59 EGGDPDNIELTVSTDTPNKKPTKGKGKK--HEADELSGDASVED-------DAFIKDCEL 109
E + N E +++ N+KPT + +K + +E DA +E A IK+ E
Sbjct: 365 EKTERSNSEDKLNSKILNEKPTTDEPEKAVEDINEHITDAQLEAMTELHDRTAVIKENER 424
Query: 110 ENQEAHEQ--DGND-ELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKE 166
E + E D D E D E +E N+ + E N ++ E + E + E +
Sbjct: 425 EKRPKLENLPDTEDQETVDINSVSEGKENNIMITLETNIEHNLKSEEEKDQEKQQMFENK 484
Query: 167 DIESQEIEAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAH 226
I+S+EI+ + ++ + GE+E N + + T+E ++ E + D ++
Sbjct: 485 LIKSEEIKDTILQTVDLVSQETGEKEANIQAVDSEVGLTKEDTQEKLGEDDKTQKDVISN 544
Query: 227 EE-----MEAHTTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGK---NVKITDSEASK 278
EA ++ ++D+ AED T DG +++E G+ N + EA
Sbjct: 545 TSDVIGTCEAADVAQKVDEDS------AED--TQSNDGKEVVEVGQKLINKPMVGPEAGG 596
Query: 279 PKDG--QDAIAQSPEKESKDYEMNANHKDG-----KKEDCVKGDPVEKEARESSKKAESG 331
K+ ++ + + +E K+ E N + ++ +G+ + + + + S
Sbjct: 597 TKEVPIKEIVEMNEIEEGKNKEQAINSSENIMDINEEPGTTEGEEITESSSTEEMEVRSV 656
Query: 332 DKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGL 391
+ D G AS KE K+ S K + T S + + + + +
Sbjct: 657 VADTDQKALGSEVQDASKVTTQIDKEKKEIPVSIKKEP---EVTVVSQPTEPQPVLIPSI 713
Query: 392 SSNTKAADLKNLFGKYGK---VLSAKVVTNARSPGAKCYGIVTMSSSTEVSRCIAHLHRT 448
+ N+ + + K G K +L + + G +SS +++ I+
Sbjct: 714 NINSDSGENKEEIGSLSKTETILPPESENPKENDNDSGTGSTADTSSIDLNLSIS----- 768
Query: 449 ELHGQLISVEKVKGDPSKKEMKKENDEKSSSRS---SGDKKNTSDRSSKTQASVKKEEKR 505
+S K G S +E +++ +R G + + + T + K EE R
Sbjct: 769 ----SFLSKTKDSGSISLQETRRQKKTLKKTRKFIVDGVEVSVTTSKIVTDSDSKTEELR 824
Query: 506 SSEKSEKKESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKG 565
+ E +E + +K E + ++ N Q E I + E++ +S K I
Sbjct: 825 FLRRQELRELRFLQKEEQRAQQQLNSKLQQQREQIFRRFEQEMMSKKRQYDQEI------ 878
Query: 566 DHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERL 625
++ ++ E++ + R + KR K + KE+ F+ M + R +E + E+
Sbjct: 879 ENLEKQQKQTIERLE--QEHTNRLRDEAKRIKGEQEKELSKFQNMLKNRKKEVINEVEKA 936
Query: 626 RRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERE--RMERER 683
+ ELR+ E ++R +E L + E+E + +++
Sbjct: 937 PK--ELRK------------------------ELMKRRKEELAQSQHAQEQEFVQKQQQE 970
Query: 684 LERERIRIEQERRKEAERIARE----REELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDP 739
L+ +I Q+++ E I RE +++L R ++ +E E+R+ ++ + + + D
Sbjct: 971 LDGSLKKIIQQQKAELANIERECLNNKQQLMRAREAAIWELEERHLQEKHQLLKQQLKDQ 1030
Query: 740 YWSENKKLSLDTDARFGHGSDYS-RQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFVG 798
Y+ + +L + Y+ R + +ER R P+ +Q S + R
Sbjct: 1031 YFMQRHQLLKRHEKETEQMQRYNQRLIEELKNRQTQERARLPK---IQRSEAKTRMAMFK 1087
Query: 799 QSEGKKARPTARREDPSFERYPKNFSDSRRNE 830
+S + T ++ +++ ++NE
Sbjct: 1088 KSLRINSTATPDQDRDKIKQFAAQEEKRQKNE 1119
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 83.6 bits (205), Expect = 9e-16
Identities = 95/380 (25%), Positives = 159/380 (41%), Gaps = 58/380 (15%)
Query: 483 GDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSE---- 538
GD+K++ KT + +E+KR E+ EK E K K + +D K D+ G+ +
Sbjct: 2 GDEKDSW--KVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCME 59
Query: 539 -SIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDK 597
+I+ S ++ S + G K P + R EK+H R EK +K K
Sbjct: 60 ITIRNSPYRREDSMEDRGEEDDSLAIKP----PQQMSRKEKVHHRKDEK------RKEKK 109
Query: 598 DYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREER 657
R KE ++ + +R + H ++ RR E ++RRE+A R
Sbjct: 110 HARVKE----KEREHERRKRHREEQDKARREWERQKRREMA------------------R 147
Query: 658 ERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIARE-REELRRQQQQL 716
E +RER+RLE +K ERER RE+ + +R + E+ERR E R RE R E+ + +
Sbjct: 148 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTM 207
Query: 717 RYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDF----D 772
R + + H P ++ L D R + +++ +D D
Sbjct: 208 REDYSDKVK------ASHWSRSPPRPPRERFELG-DGRKPVKEEKMEERDLLSDLQDISD 260
Query: 773 HRERGRFPESSAVQS---SSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSD---- 825
+ ESS+ +S S E + + EG + + E+ E + S+
Sbjct: 261 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 320
Query: 826 SRRNEPPPPRNELRESDRRE 845
S ++ E+ E + RE
Sbjct: 321 SEQSAEEVSEEEMSEDEERE 340
Score = 77.0 bits (188), Expect = 8e-14
Identities = 96/375 (25%), Positives = 161/375 (42%), Gaps = 62/375 (16%)
Query: 466 KKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKD 525
KK K++ ++ R KN+ DR SK + S E+ E ++ I
Sbjct: 20 KKRRKEQEEKAEIKR----LKNSDDRDSK---------RDSLEEGELRDHCMEITIRNSP 66
Query: 526 EKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKE 585
+ ++ + EE ++ K P M + + H R + R EK H R KE
Sbjct: 67 YRREDSME-------DRGEEDDSLAIKPPQQM---SRKEKVHHRKDEK-RKEKKHARVKE 115
Query: 586 KERASLDKKRDKDYRRKEILPFEKMKEQRL-REHLVRFERLRRAMELRRRREIAERERRE 644
KER +KR ++ + K +E+ K + + REH RR R+ E+ R+
Sbjct: 116 KEREHERRKRHREEQDKARREWERQKRREMAREH------------SRRERDRLEQLERK 163
Query: 645 RERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAE---- 700
RER R +RE+++ +R Q+ERER ER+K ERE +R + + +A
Sbjct: 164 RERERKMREQQKEQREQKERERRAEERRK-EREARREVSAHHRTMREDYSDKVKASHWSR 222
Query: 701 ---RIAREREELRRQQQQLRYEQ-EKRNSLKRPRDVDHRRDDPYWSENKKLSLD-TDARF 755
R RER EL ++ ++ E+ E+R+ L +D+ SE K S + + A
Sbjct: 223 SPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISD-------SERKTSSAESSSAES 275
Query: 756 GHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFVGQSEGKKARPTARREDPS 815
G GS+ ++ + E G E S + E + G + + + +A E+ S
Sbjct: 276 GSGSEEEEEEEE----EEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSA--EEVS 329
Query: 816 FERYPKNFSDSRRNE 830
E ++ + R NE
Sbjct: 330 EEEMSED--EERENE 342
Score = 55.5 bits (132), Expect = 3e-07
Identities = 84/397 (21%), Positives = 156/397 (39%), Gaps = 82/397 (20%)
Query: 582 RSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERE 641
R +++E+A + + ++ D R + + ++E LR+H + +R + RRE + +
Sbjct: 23 RKEQEEKAEIKRLKNSDDRDSKR---DSLEEGELRDHCMEIT-IRNSPY---RREDSMED 75
Query: 642 RRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAER 701
R E + I+ ++ R ++ R + +R++ + R++ E+ER E ERRK
Sbjct: 76 RGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVK----EKER---EHERRK---- 124
Query: 702 IAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDY 761
R REE + +++ +E++KR + R +H R
Sbjct: 125 --RHREEQDKARRE--WERQKRREMAR----EHSR------------------------- 151
Query: 762 SRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERYPK 821
R+++R + R+R R + Q E+++R E +K R R +
Sbjct: 152 -RERDRLEQLE-RKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRE 209
Query: 822 NFSDS------RRNEPPPPRNELRESD-RREVRGERDERRTVIIHDRPDITHPRHPREAG 874
++SD R+ P PPR D R+ V+ E+ E R ++ D DI+ +
Sbjct: 210 DYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERD-LLSDLQDISDSERKTSSA 268
Query: 875 PNPSRPTSWKSE---------------GSMSTDKRETRVERPERSGREVSGHSVRGAPPG 919
+ S + SE S ++ E E E +G S + A
Sbjct: 269 ESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEV 328
Query: 920 NRSSASGYGSREGDRGVIT------DRGGGSQHYPEE 950
+ S RE + ++ DR G EE
Sbjct: 329 SEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 365
Score = 43.9 bits (102), Expect = 8e-04
Identities = 30/136 (22%), Positives = 65/136 (47%), Gaps = 23/136 (16%)
Query: 464 PSKKEMKKENDEKSSSR--SSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKI 521
P K+E +E D S + S ++K +S SS ++ EE+ E+ E++E +++
Sbjct: 240 PVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 299
Query: 522 EGKDEK----------NDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPS 571
E ++E+ N AS Q++E + + E + ++ H++++ ++
Sbjct: 300 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES-------- 351
Query: 572 RRGRYEKIHGRSKEKE 587
R+++ G S+E E
Sbjct: 352 ---RFDRDSGESEEAE 364
Score = 43.5 bits (101), Expect = 0.001
Identities = 39/133 (29%), Positives = 65/133 (48%), Gaps = 19/133 (14%)
Query: 93 SGDASVEDDAFIKDCELENQEAHEQDG--NDELKDSEEFGENEEENVHSKELLSAEENKR 150
S ++S + + E E +E E++G ++E ++ EE E EEE S ++E++
Sbjct: 267 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQS-- 324
Query: 151 AHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSK 210
A E+ E E ED E+E+ E+ + E D GE EE E+++ G+GT
Sbjct: 325 AEEVSEEEMSEDEEREN-ENHLLVVPESRFD----RDSGESEEAEEEV---GEGT----- 371
Query: 211 PLPSEGSLAEADH 223
P +L E D+
Sbjct: 372 --PQSSALTEGDY 382
Score = 41.2 bits (95), Expect = 0.005
Identities = 54/308 (17%), Positives = 114/308 (37%), Gaps = 39/308 (12%)
Query: 464 PSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEG 523
P ++ +KE +KK+ + + + +K + +K+ ++ + ++
Sbjct: 87 PPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMA 146
Query: 524 KDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRS 583
++ S + + +++ E K+ R + +K
Sbjct: 147 REH------SRRERDRLEQLERKRE--------------------RERKMREQQKEQREQ 180
Query: 584 KEKERASLDKKRDKDYRRKEILPFEKMKE----QRLREHLVRF--ERLRRAMEL-RRRRE 636
KE+ER + +++++++ RR+ M+E + H R R EL R+
Sbjct: 181 KERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKP 240
Query: 637 IAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERR 696
+ E + ER+ + +++ + ER E E E E E E E +E
Sbjct: 241 VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESE 300
Query: 697 KEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFG 756
+E E E EE E+ S + + + D+ +EN L + ++RF
Sbjct: 301 EEEEEEEEEEEETGSNS-----EEASEQSAEEVSEEEMSEDEERENENHLLVV-PESRFD 354
Query: 757 HGSDYSRQ 764
S S +
Sbjct: 355 RDSGESEE 362
Score = 39.7 bits (91), Expect = 0.015
Identities = 58/325 (17%), Positives = 123/325 (37%), Gaps = 61/325 (18%)
Query: 51 RLKQAIEEEGGDPDNI------ELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFI 104
R + ++E+ G + D++ +++ ++K K K KKH A V++
Sbjct: 68 RREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKH--------ARVKE---- 115
Query: 105 KDCELENQEAHEQDGNDELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIE 164
K+ E E ++ H ++ + ++ E E HS+ E + +E +E
Sbjct: 116 KEREHERRKRHREEQDKARREWERQKRREMAREHSRR--------------ERDRLEQLE 161
Query: 165 KEDIESQEIEAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHT 224
++ +++ Q+ E + E E ++ + +EVS
Sbjct: 162 RKRERERKMREQQKEQ-----REQKERERRAEERRKEREARREVS--------------- 201
Query: 225 AHEEMEAHTTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQD 284
AH H T++E D + + + + +L + K VK E
Sbjct: 202 AH-----HRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ 256
Query: 285 AIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSS 344
I+ S K S +A G +E+ + E+E E +E ++E++ ++
Sbjct: 257 DISDSERKTSSAESSSAESGSGSEEE----EEEEEEEEEEGSTSEESEEEEEEEEEEEEE 312
Query: 345 TGASGQAKSSSKESKDSKTSSKDDK 369
TG++ + S + S+ +D+
Sbjct: 313 TGSNSEEASEQSAEEVSEEEMSEDE 337
Score = 37.7 bits (86), Expect = 0.056
Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 11/110 (10%)
Query: 133 EEENVHSKELLS-------AEENKRAHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLT 185
+EE + ++LLS +E + E AE E+E+ E +E E +EG
Sbjct: 242 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEE-EEEEGSTSEESE 300
Query: 186 AQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTV 235
++ EEEE E++ +G ++E S+ E S E E E H V
Sbjct: 301 EEEEEEEEEEEE---TGSNSEEASEQSAEEVSEEEMSEDEERENENHLLV 347
Score = 30.8 bits (68), Expect = 6.9
Identities = 26/135 (19%), Positives = 55/135 (40%), Gaps = 2/135 (1%)
Query: 117 QDGNDELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQ 176
+D +D++K S EL + + ++ E + + D++ DI E +
Sbjct: 209 EDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ--DISDSERKTS 266
Query: 177 EGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVK 236
E + + EEEE E++ T E S+ E E + ++ E + + +
Sbjct: 267 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 326
Query: 237 EAEDDNISVTIQAED 251
E ++ +S + E+
Sbjct: 327 EVSEEEMSEDEEREN 341
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 83.2 bits (204), Expect = 1e-15
Identities = 148/775 (19%), Positives = 278/775 (35%), Gaps = 130/775 (16%)
Query: 108 ELENQEAHEQDGNDELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKED 167
+L+ Q + G + K S + + + S + + KR + + ++EKE
Sbjct: 728 DLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEI 787
Query: 168 IESQEIEAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHE 227
+I A +D + E+EK D + EGS +A+
Sbjct: 788 KSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQER 847
Query: 228 E--------MEAHTTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKP 279
E ++ TT+ E D + + + DG D L +GK T E K
Sbjct: 848 ETFSSAEGTVDKDTTIMELRD-----RLPKKQQASASTDGVDKL-SGKEQSFTSLEVRKV 901
Query: 280 ---------------KDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARES 324
K QD ++ EK K + + +D KK+ KG +K+ +
Sbjct: 902 AETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQS-KKGTEEKKKPSDF 960
Query: 325 SKKAESGDKEKDTLKKGPSST-----------------GASGQAKSSSKESKDSKTSSKD 367
KK +++ ++ G + + SK+ +D + KD
Sbjct: 961 KKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKD 1020
Query: 368 DKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLS-AKVVTNARSPGAKC 426
+ + S G S + + D K+ G YG+ K++ + C
Sbjct: 1021 ELSDYAEKSTGKGDSCDS-----------SEDKKSKNGAYGREKKRCKLLGKSSRKRQDC 1069
Query: 427 YGIVTMSSSTEVSRCIA---HLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSG 483
T S + C + L R EL + + + KE++ + + SS
Sbjct: 1070 SSSDTEKYSMKEDGCNSSDKRLKRIELRER----RNLSSKRNTKEIQSGSSSSDAEESSE 1125
Query: 484 DKKNTSDR-SSKTQASVKKEEKRSSEKSEKKE------SKDTKKIEGKDEKNDNGASGQT 536
D K R SSK +A + KE+KR+S ++ K S + IE D++N G
Sbjct: 1126 DNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIED-DDQNSIGEGSSD 1184
Query: 537 SESIKKSEEKKRISSK------------SPGHMVILDQTKGDHCRPSRRGR---YEKIHG 581
+ IK E +SS S V +D D+ +R + E+I
Sbjct: 1185 EQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKA 1244
Query: 582 RSKEKERASLDKKRDKDYRR--------------------KEILPFEKMKEQRLREHLVR 621
E S D + ++ +R + E+ K+ R R L+R
Sbjct: 1245 NLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLR 1304
Query: 622 FE----------------RLRRAMELRRRREIAERERRERE--RIRIIREREERERLQRE 663
+ + + ++ R RR+++ + + + + E E E QR
Sbjct: 1305 HKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRP 1364
Query: 664 RERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKR 723
R R + + E +R +++ +R RI+++++ E + + E EE + ++++ E+E+
Sbjct: 1365 RTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEE---EEEEE 1421
Query: 724 NSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGR 778
+ + D + + +K+ D R + ++ R RER R
Sbjct: 1422 EEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAERERER 1476
Score = 75.1 bits (183), Expect = 3e-13
Identities = 150/747 (20%), Positives = 291/747 (38%), Gaps = 155/747 (20%)
Query: 45 KTVLISRLKQAIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFI 104
K+ +IS+ K+ + E + D+ EL + +K KK + D+S +
Sbjct: 761 KSSIISKKKRQTQSESSNYDS-ELEKEIKSMSKIGAARTTKKRIPNTKDFDSSED----- 814
Query: 105 KDCELENQEAHEQDGNDELKDSEEFGENEEENVHSKELLSAEEN---------------- 148
E +++ + G+ LK S+E ++ E +E S+ E
Sbjct: 815 ---EKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLP 871
Query: 149 KRAHELIEAEGIEDI--EKEDIESQEI-------------------EAQEGEDDTF--LT 185
K+ +G++ + +++ S E+ + Q+G D
Sbjct: 872 KKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFL 931
Query: 186 AQDGEEEENEKDIAGSGDGTQEVSKPLP---------------SEGS--LAEADHTAH-- 226
+D +E +E D S GT+E KP S+G+ L E + H
Sbjct: 932 KKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFP 991
Query: 227 ---EEMEAHTTVKEAEDDNI-SVTIQAEDAITLDFDGDDLLE--TGKNVKITDSEASKPK 280
++++ TT E + I T + +D ++ D E TGK SE K K
Sbjct: 992 KGIKQIKNGTTDGEKKSKKIRDKTSKKKDELS------DYAEKSTGKGDSCDSSEDKKSK 1045
Query: 281 DG-------QDAIAQSPEKESKDYEMNANHKDGKKED-CVKGDPVEKEARESSKKAESGD 332
+G + + ++ +D + K KED C D K ++ S
Sbjct: 1046 NGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSK 1105
Query: 333 KEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSS---GSSTKNIWVS 389
+ ++ G SS+ A ++ + K K +TSSK +S + K ++
Sbjct: 1106 RNTKEIQSGSSSSDAEESSEDNKK--KKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADIT 1163
Query: 390 GLSSNTKAADLKNLFGKYG------KVLSAKVVTNARSPGAKCYGIVTMSSSTEVS---- 439
SS+ D +N G+ K ++ +V ++ + + G +S S V+
Sbjct: 1164 SSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDD 1223
Query: 440 --------RCIAHLHRTELHGQLISVEKVKGDPSKKEMKKEN---------DEKSSSRSS 482
R + E+ L S E D +E KK DE++ ++ +
Sbjct: 1224 DDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVN 1283
Query: 483 GDKKNTSDRSSKTQ---------ASVKKEEKRSSEKSEKKESKDTK-----KIEGKDEKN 528
+ + S+ S K + +V E +K++ KE K+ K K+ +D ++
Sbjct: 1284 SESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSED 1343
Query: 529 DNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKER 588
+ SE + +SE+++R ++S L++ + + + +R R + S E +
Sbjct: 1344 SDFQESGVSEEVSESEDEQRPRTRS-AKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS 1402
Query: 589 ASLDKKRDKDYRRKEILPFEKMKE-------------QRLREHLVRFERLRRAM------ 629
S +++ +K+ +E E+ +E +++R+ +++ ++LR
Sbjct: 1403 NSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRK-ILKDDKLRTETQNALKE 1461
Query: 630 ELRRRREIAERERRERERIRIIREREE 656
E RR+ IAERER ERE++R + E E+
Sbjct: 1462 EEERRKRIAERER-EREKLREVIEIED 1487
Score = 53.5 bits (127), Expect = 1e-06
Identities = 147/883 (16%), Positives = 324/883 (36%), Gaps = 154/883 (17%)
Query: 67 ELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFIKDCELENQEAH---EQDGNDEL 123
+L +T N K + + E+S + K + ++AH E+D N E
Sbjct: 320 KLIETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEF 379
Query: 124 KDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQEGEDDTF 183
+ + N+E+N +++ A+ +A + E +EK+DI E + + D+
Sbjct: 380 RAMDAV--NKEKNTKEHKVIDAKFETKARK---GEKPCALEKKDISKSEAKLSRKQVDSE 434
Query: 184 LTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAEDDNI 243
Q+ EE + + G+ + K P ++ + + ++V E +N+
Sbjct: 435 HMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENL 494
Query: 244 SVTIQAEDAITLDFDGDDLLE-------------------------TGK-----NVKITD 273
++ + ++ DG E T K VK+T
Sbjct: 495 ETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTP 554
Query: 274 -------------SEASKPKDGQDAIAQSPE-------KESKDYE--------MNANHKD 305
E + KDG + +P+ +E+ D E + D
Sbjct: 555 VSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESD 614
Query: 306 GKKEDCVKGDPVEKEARESSKKAESGDKEKDTLK-------------KGPSSTGA----- 347
++ VK P+ + + + S ++ +T+K K SS A
Sbjct: 615 LRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPK 674
Query: 348 -SGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAA-DLKNLFG 405
+ KS E+ D + S + S S SS+ + ++ + +N K DLK G
Sbjct: 675 PNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAG 734
Query: 406 KYGKVLSAKVVTNARS----PGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKV- 460
K K + + + S K +S ++ + + +EL ++ S+ K+
Sbjct: 735 KDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIG 794
Query: 461 ------KGDPSKKEMKKENDEKSSSR---SSGDKKNTSDRSSKTQASVKKEEKRSSEKSE 511
K P+ K+ DEK S + + G K + + + + +K+E+ + +E
Sbjct: 795 AARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAE 854
Query: 512 KKESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDH---- 567
KDT +E +D + +++ + K K++ + V + K H
Sbjct: 855 GTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTK 914
Query: 568 -CRPSRRG-------------RYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQ 613
C+ + G E K+ ++ + +KK+ D+++K ++ E+ E
Sbjct: 915 TCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKK-VIKMEQQYES 973
Query: 614 RL--------REHLVRFERLRRAME------LRRRREIAERERRERERIRIIRER----- 654
RE + F + + ++ ++ ++I ++ ++++ + E+
Sbjct: 974 SSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKG 1033
Query: 655 ------EERERLQ----RERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAR 704
E+++ RE++R ++ K R+R + + E+ ++++ +++ +
Sbjct: 1034 DSCDSSEDKKSKNGAYGREKKRCKL-LGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLK 1092
Query: 705 EREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQ 764
E R+ + ++ S D + +D NKK T ++ ++
Sbjct: 1093 RIELRERRNLSSKRNTKEIQSGSSSSDAEESSED-----NKKKKQRTSSKKKAVIVKEKK 1147
Query: 765 QNRFNDFDHRERGRFPESSAVQSSSFERRDRFVGQSEGKKARP 807
+N R++ SS+ ++ G S+ +K +P
Sbjct: 1148 RNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKP 1190
Score = 31.6 bits (70), Expect = 4.0
Identities = 34/131 (25%), Positives = 52/131 (39%), Gaps = 32/131 (24%)
Query: 434 SSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSS 493
S ++++ + LH H S E P + M + D+ S S S+ D S
Sbjct: 7 SESKLNTLVQKLHDFLAHSSEESEET--SSPPRLAMNQNTDKISGSGSNSDMMENS---- 60
Query: 494 KTQASVKKEEKRSSEK--------SEKKESKDTKKIEGKDEK------------NDNGAS 533
K+E SSEK S++K S TK +E DEK N+N +
Sbjct: 61 ------KEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSEN 114
Query: 534 GQTSESIKKSE 544
T +S+ K +
Sbjct: 115 DITMQSLPKED 125
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 83.2 bits (204), Expect = 1e-15
Identities = 148/775 (19%), Positives = 278/775 (35%), Gaps = 130/775 (16%)
Query: 108 ELENQEAHEQDGNDELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKED 167
+L+ Q + G + K S + + + S + + KR + + ++EKE
Sbjct: 766 DLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEI 825
Query: 168 IESQEIEAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHE 227
+I A +D + E+EK D + EGS +A+
Sbjct: 826 KSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQER 885
Query: 228 E--------MEAHTTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKP 279
E ++ TT+ E D + + + DG D L +GK T E K
Sbjct: 886 ETFSSAEGTVDKDTTIMELRD-----RLPKKQQASASTDGVDKL-SGKEQSFTSLEVRKV 939
Query: 280 ---------------KDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARES 324
K QD ++ EK K + + +D KK+ KG +K+ +
Sbjct: 940 AETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQS-KKGTEEKKKPSDF 998
Query: 325 SKKAESGDKEKDTLKKGPSST-----------------GASGQAKSSSKESKDSKTSSKD 367
KK +++ ++ G + + SK+ +D + KD
Sbjct: 999 KKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKD 1058
Query: 368 DKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLS-AKVVTNARSPGAKC 426
+ + S G S + + D K+ G YG+ K++ + C
Sbjct: 1059 ELSDYAEKSTGKGDSCDS-----------SEDKKSKNGAYGREKKRCKLLGKSSRKRQDC 1107
Query: 427 YGIVTMSSSTEVSRCIA---HLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSG 483
T S + C + L R EL + + + KE++ + + SS
Sbjct: 1108 SSSDTEKYSMKEDGCNSSDKRLKRIELRER----RNLSSKRNTKEIQSGSSSSDAEESSE 1163
Query: 484 DKKNTSDR-SSKTQASVKKEEKRSSEKSEKKE------SKDTKKIEGKDEKNDNGASGQT 536
D K R SSK +A + KE+KR+S ++ K S + IE D++N G
Sbjct: 1164 DNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIED-DDQNSIGEGSSD 1222
Query: 537 SESIKKSEEKKRISSK------------SPGHMVILDQTKGDHCRPSRRGR---YEKIHG 581
+ IK E +SS S V +D D+ +R + E+I
Sbjct: 1223 EQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKA 1282
Query: 582 RSKEKERASLDKKRDKDYRR--------------------KEILPFEKMKEQRLREHLVR 621
E S D + ++ +R + E+ K+ R R L+R
Sbjct: 1283 NLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLR 1342
Query: 622 FE----------------RLRRAMELRRRREIAERERRERE--RIRIIREREERERLQRE 663
+ + + ++ R RR+++ + + + + E E E QR
Sbjct: 1343 HKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRP 1402
Query: 664 RERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKR 723
R R + + E +R +++ +R RI+++++ E + + E EE + ++++ E+E+
Sbjct: 1403 RTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEE---EEEEE 1459
Query: 724 NSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGR 778
+ + D + + +K+ D R + ++ R RER R
Sbjct: 1460 EEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAERERER 1514
Score = 75.1 bits (183), Expect = 3e-13
Identities = 150/747 (20%), Positives = 291/747 (38%), Gaps = 155/747 (20%)
Query: 45 KTVLISRLKQAIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFI 104
K+ +IS+ K+ + E + D+ EL + +K KK + D+S +
Sbjct: 799 KSSIISKKKRQTQSESSNYDS-ELEKEIKSMSKIGAARTTKKRIPNTKDFDSSED----- 852
Query: 105 KDCELENQEAHEQDGNDELKDSEEFGENEEENVHSKELLSAEEN---------------- 148
E +++ + G+ LK S+E ++ E +E S+ E
Sbjct: 853 ---EKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLP 909
Query: 149 KRAHELIEAEGIEDI--EKEDIESQEI-------------------EAQEGEDDTF--LT 185
K+ +G++ + +++ S E+ + Q+G D
Sbjct: 910 KKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFL 969
Query: 186 AQDGEEEENEKDIAGSGDGTQEVSKPLP---------------SEGS--LAEADHTAH-- 226
+D +E +E D S GT+E KP S+G+ L E + H
Sbjct: 970 KKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFP 1029
Query: 227 ---EEMEAHTTVKEAEDDNI-SVTIQAEDAITLDFDGDDLLE--TGKNVKITDSEASKPK 280
++++ TT E + I T + +D ++ D E TGK SE K K
Sbjct: 1030 KGIKQIKNGTTDGEKKSKKIRDKTSKKKDELS------DYAEKSTGKGDSCDSSEDKKSK 1083
Query: 281 DG-------QDAIAQSPEKESKDYEMNANHKDGKKED-CVKGDPVEKEARESSKKAESGD 332
+G + + ++ +D + K KED C D K ++ S
Sbjct: 1084 NGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSK 1143
Query: 333 KEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSS---GSSTKNIWVS 389
+ ++ G SS+ A ++ + K K +TSSK +S + K ++
Sbjct: 1144 RNTKEIQSGSSSSDAEESSEDNKK--KKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADIT 1201
Query: 390 GLSSNTKAADLKNLFGKYG------KVLSAKVVTNARSPGAKCYGIVTMSSSTEVS---- 439
SS+ D +N G+ K ++ +V ++ + + G +S S V+
Sbjct: 1202 SSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDD 1261
Query: 440 --------RCIAHLHRTELHGQLISVEKVKGDPSKKEMKKEN---------DEKSSSRSS 482
R + E+ L S E D +E KK DE++ ++ +
Sbjct: 1262 DDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVN 1321
Query: 483 GDKKNTSDRSSKTQ---------ASVKKEEKRSSEKSEKKESKDTK-----KIEGKDEKN 528
+ + S+ S K + +V E +K++ KE K+ K K+ +D ++
Sbjct: 1322 SESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSED 1381
Query: 529 DNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKER 588
+ SE + +SE+++R ++S L++ + + + +R R + S E +
Sbjct: 1382 SDFQESGVSEEVSESEDEQRPRTRS-AKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS 1440
Query: 589 ASLDKKRDKDYRRKEILPFEKMKE-------------QRLREHLVRFERLRRAM------ 629
S +++ +K+ +E E+ +E +++R+ +++ ++LR
Sbjct: 1441 NSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRK-ILKDDKLRTETQNALKE 1499
Query: 630 ELRRRREIAERERRERERIRIIREREE 656
E RR+ IAERER ERE++R + E E+
Sbjct: 1500 EEERRKRIAERER-EREKLREVIEIED 1525
Score = 53.5 bits (127), Expect = 1e-06
Identities = 147/883 (16%), Positives = 324/883 (36%), Gaps = 154/883 (17%)
Query: 67 ELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFIKDCELENQEAH---EQDGNDEL 123
+L +T N K + + E+S + K + ++AH E+D N E
Sbjct: 358 KLIETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEF 417
Query: 124 KDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQEGEDDTF 183
+ + N+E+N +++ A+ +A + E +EK+DI E + + D+
Sbjct: 418 RAMDAV--NKEKNTKEHKVIDAKFETKARK---GEKPCALEKKDISKSEAKLSRKQVDSE 472
Query: 184 LTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAEDDNI 243
Q+ EE + + G+ + K P ++ + + ++V E +N+
Sbjct: 473 HMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENL 532
Query: 244 SVTIQAEDAITLDFDGDDLLE-------------------------TGK-----NVKITD 273
++ + ++ DG E T K VK+T
Sbjct: 533 ETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTP 592
Query: 274 -------------SEASKPKDGQDAIAQSPE-------KESKDYE--------MNANHKD 305
E + KDG + +P+ +E+ D E + D
Sbjct: 593 VSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESD 652
Query: 306 GKKEDCVKGDPVEKEARESSKKAESGDKEKDTLK-------------KGPSSTGA----- 347
++ VK P+ + + + S ++ +T+K K SS A
Sbjct: 653 LRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPK 712
Query: 348 -SGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAA-DLKNLFG 405
+ KS E+ D + S + S S SS+ + ++ + +N K DLK G
Sbjct: 713 PNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAG 772
Query: 406 KYGKVLSAKVVTNARS----PGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKV- 460
K K + + + S K +S ++ + + +EL ++ S+ K+
Sbjct: 773 KDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIG 832
Query: 461 ------KGDPSKKEMKKENDEKSSSR---SSGDKKNTSDRSSKTQASVKKEEKRSSEKSE 511
K P+ K+ DEK S + + G K + + + + +K+E+ + +E
Sbjct: 833 AARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAE 892
Query: 512 KKESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDH---- 567
KDT +E +D + +++ + K K++ + V + K H
Sbjct: 893 GTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTK 952
Query: 568 -CRPSRRG-------------RYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQ 613
C+ + G E K+ ++ + +KK+ D+++K ++ E+ E
Sbjct: 953 TCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKK-VIKMEQQYES 1011
Query: 614 RL--------REHLVRFERLRRAME------LRRRREIAERERRERERIRIIRER----- 654
RE + F + + ++ ++ ++I ++ ++++ + E+
Sbjct: 1012 SSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKG 1071
Query: 655 ------EERERLQ----RERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAR 704
E+++ RE++R ++ K R+R + + E+ ++++ +++ +
Sbjct: 1072 DSCDSSEDKKSKNGAYGREKKRCKL-LGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLK 1130
Query: 705 EREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQ 764
E R+ + ++ S D + +D NKK T ++ ++
Sbjct: 1131 RIELRERRNLSSKRNTKEIQSGSSSSDAEESSED-----NKKKKQRTSSKKKAVIVKEKK 1185
Query: 765 QNRFNDFDHRERGRFPESSAVQSSSFERRDRFVGQSEGKKARP 807
+N R++ SS+ ++ G S+ +K +P
Sbjct: 1186 RNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKP 1228
Score = 35.4 bits (80), Expect = 0.28
Identities = 40/155 (25%), Positives = 62/155 (40%), Gaps = 25/155 (16%)
Query: 434 SSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSS 493
S ++++ + LH H S E P + M + D+ S S S+ D S
Sbjct: 7 SESKLNTLVQKLHDFLAHSSEESEET--SSPPRLAMNQNTDKISGSGSNSDMMENS---- 60
Query: 494 KTQASVKKEEKRSSEK--------SEKKESKDTKKIEGKDEKNDNGASGQTSESIKKSEE 545
K+E SSEK S++K S TK +E DEK + + S + SE
Sbjct: 61 ------KEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSEN 114
Query: 546 KKRISSKSPGHMV-----ILDQTKGDHCRPSRRGR 575
+ S G ++ +L++ K D P R R
Sbjct: 115 DITMQSLPKGTVIVQPEPVLNEDKDDFKGPEFRSR 149
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 82.8 bits (203), Expect = 2e-15
Identities = 56/129 (43%), Positives = 81/129 (62%), Gaps = 13/129 (10%)
Query: 626 RRAMELRRRREIAERERRERERIRIIREREERERLQRE---RERLEIERQKLERERMER- 681
RR ++ ++R++ ERER ERER+ RER ERERL+RE RERL E+++LERER ER
Sbjct: 144 RRQLQEQQRQKELERERLERERME--RERLERERLERERLERERL--EQEQLERERQERE 199
Query: 682 --ERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDP 739
ERLER+ QER + ER+ RER+E +Q++ R E+ +R +R R R+
Sbjct: 200 RQERLERQERLERQERLERQERLDRERQE---RQERERLERLERERQERERQEQLEREQL 256
Query: 740 YWSENKKLS 748
W +++S
Sbjct: 257 EWERERRIS 265
Score = 81.3 bits (199), Expect = 4e-15
Identities = 59/135 (43%), Positives = 86/135 (63%), Gaps = 16/135 (11%)
Query: 609 KMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLE 668
+++EQ+ ++ L R ERL R R RE ERER ERER+ RER E+E+L+RER+ E
Sbjct: 146 QLQEQQRQKELER-ERLERE---RMERERLERERLERERLE--RERLEQEQLERERQERE 199
Query: 669 IERQKLERERMER-ERLER----ERIRIEQERRKEAERIAREREELRRQQQ----QLRYE 719
+ + +ER+ER ERLER +R R E++ R+ ER+ RER+E RQ+Q QL +E
Sbjct: 200 RQERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLEREQLEWE 259
Query: 720 QEKR-NSLKRPRDVD 733
+E+R +S P V+
Sbjct: 260 RERRISSAAAPASVE 274
Score = 72.4 bits (176), Expect = 2e-12
Identities = 52/120 (43%), Positives = 73/120 (60%), Gaps = 13/120 (10%)
Query: 582 RSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERE 641
R KE ER L+++R +E L E+++ +RL + E+L R + R R+E ER+
Sbjct: 152 RQKELERERLERER----MERERLERERLERERLERERLEQEQLERERQERERQERLERQ 207
Query: 642 RRERERIRIIR-EREERERLQR-ERERLEIERQKLERERMERER---LERERIRIEQERR 696
R + R+ R ER +RER +R ERERLE +LERER ERER LERE++ E+ERR
Sbjct: 208 ERLERQERLERQERLDRERQERQERERLE----RLERERQERERQEQLEREQLEWERERR 263
Score = 72.0 bits (175), Expect = 3e-12
Identities = 37/94 (39%), Positives = 63/94 (67%), Gaps = 2/94 (2%)
Query: 645 RERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAR 704
+E + I R + + ++ Q+E ER +ER+++ERER+ERERLERER+ E+ +++ ER +
Sbjct: 137 QEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQ 196
Query: 705 EREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDD 738
ERE R ++Q R E+++R L+R +D R +
Sbjct: 197 ERERQERLERQERLERQER--LERQERLDRERQE 228
Score = 69.7 bits (169), Expect = 1e-11
Identities = 50/126 (39%), Positives = 74/126 (58%), Gaps = 8/126 (6%)
Query: 585 EKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRE 644
E +R L +++ + +E L E+M+ +RL + ERL R R +E ERER+E
Sbjct: 141 EIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERE---RLEQEQLERERQE 197
Query: 645 RERIRIIREREERERLQR--ERERLEIERQ-KLERERMERERLERERIRIEQERRKEAER 701
RER + +E ER +R +ERL+ ERQ + ERER+ ERLERER E++ + E E+
Sbjct: 198 RERQERLERQERLERQERLERQERLDRERQERQERERL--ERLERERQERERQEQLEREQ 255
Query: 702 IARERE 707
+ ERE
Sbjct: 256 LEWERE 261
Score = 52.4 bits (124), Expect = 2e-06
Identities = 33/94 (35%), Positives = 54/94 (57%), Gaps = 4/94 (4%)
Query: 573 RGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELR 632
R R E+ + E+ L+++R + R++ + E+++ Q E R +R R+ + R
Sbjct: 173 RERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQER 232
Query: 633 RRREIAERERRERERIRIIREREERERLQRERER 666
R E ERER+ERER +E+ ERE+L+ ERER
Sbjct: 233 ERLERLERERQERER----QEQLEREQLEWERER 262
Score = 41.2 bits (95), Expect = 0.005
Identities = 44/188 (23%), Positives = 80/188 (42%), Gaps = 10/188 (5%)
Query: 648 IRIIREREERERLQRERERLEIERQKLERERMERERLERERIRI-EQERRKEAERIARER 706
+ ++ +E L R+ +L + Q +E LE +R ++ EQ+R+KE ER ER
Sbjct: 108 LEVLNSQETGPTLPRQNSQLPAQVQN----GPSQEELEIQRRQLQEQQRQKELERERLER 163
Query: 707 EELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQN 766
E + R++ L E+ +R L+R R + + ++ L+ R RQ+
Sbjct: 164 ERMERER--LERERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQER 221
Query: 767 RFNDFDHRERGRFPESSAVQSSSFERRDRFV-GQSEGKKARPTARREDPSFERYPKN--F 823
+ R+ E + ER+++ Q E ++ R + P+ P N
Sbjct: 222 LDRERQERQERERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVL 281
Query: 824 SDSRRNEP 831
DS +EP
Sbjct: 282 GDSSASEP 289
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 82.8 bits (203), Expect = 2e-15
Identities = 56/129 (43%), Positives = 81/129 (62%), Gaps = 13/129 (10%)
Query: 626 RRAMELRRRREIAERERRERERIRIIREREERERLQRE---RERLEIERQKLERERMER- 681
RR ++ ++R++ ERER ERER+ RER ERERL+RE RERL E+++LERER ER
Sbjct: 144 RRQLQEQQRQKELERERLERERME--RERLERERLERERLERERL--EQEQLERERQERE 199
Query: 682 --ERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDP 739
ERLER+ QER + ER+ RER+E +Q++ R E+ +R +R R R+
Sbjct: 200 RQERLERQERLERQERLERQERLDRERQE---RQERERLERLERERQERERQEQLEREQL 256
Query: 740 YWSENKKLS 748
W +++S
Sbjct: 257 EWERERRIS 265
Score = 81.3 bits (199), Expect = 4e-15
Identities = 59/135 (43%), Positives = 86/135 (63%), Gaps = 16/135 (11%)
Query: 609 KMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLE 668
+++EQ+ ++ L R ERL R R RE ERER ERER+ RER E+E+L+RER+ E
Sbjct: 146 QLQEQQRQKELER-ERLERE---RMERERLERERLERERLE--RERLEQEQLERERQERE 199
Query: 669 IERQKLERERMER-ERLER----ERIRIEQERRKEAERIAREREELRRQQQ----QLRYE 719
+ + +ER+ER ERLER +R R E++ R+ ER+ RER+E RQ+Q QL +E
Sbjct: 200 RQERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLEREQLEWE 259
Query: 720 QEKR-NSLKRPRDVD 733
+E+R +S P V+
Sbjct: 260 RERRISSAAAPASVE 274
Score = 72.4 bits (176), Expect = 2e-12
Identities = 52/120 (43%), Positives = 73/120 (60%), Gaps = 13/120 (10%)
Query: 582 RSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERE 641
R KE ER L+++R +E L E+++ +RL + E+L R + R R+E ER+
Sbjct: 152 RQKELERERLERER----MERERLERERLERERLERERLEQEQLERERQERERQERLERQ 207
Query: 642 RRERERIRIIR-EREERERLQR-ERERLEIERQKLERERMERER---LERERIRIEQERR 696
R + R+ R ER +RER +R ERERLE +LERER ERER LERE++ E+ERR
Sbjct: 208 ERLERQERLERQERLDRERQERQERERLE----RLERERQERERQEQLEREQLEWERERR 263
Score = 72.0 bits (175), Expect = 3e-12
Identities = 37/94 (39%), Positives = 63/94 (67%), Gaps = 2/94 (2%)
Query: 645 RERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAR 704
+E + I R + + ++ Q+E ER +ER+++ERER+ERERLERER+ E+ +++ ER +
Sbjct: 137 QEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQ 196
Query: 705 EREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDD 738
ERE R ++Q R E+++R L+R +D R +
Sbjct: 197 ERERQERLERQERLERQER--LERQERLDRERQE 228
Score = 69.7 bits (169), Expect = 1e-11
Identities = 50/126 (39%), Positives = 74/126 (58%), Gaps = 8/126 (6%)
Query: 585 EKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRE 644
E +R L +++ + +E L E+M+ +RL + ERL R R +E ERER+E
Sbjct: 141 EIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERE---RLEQEQLERERQE 197
Query: 645 RERIRIIREREERERLQR--ERERLEIERQ-KLERERMERERLERERIRIEQERRKEAER 701
RER + +E ER +R +ERL+ ERQ + ERER+ ERLERER E++ + E E+
Sbjct: 198 RERQERLERQERLERQERLERQERLDRERQERQERERL--ERLERERQERERQEQLEREQ 255
Query: 702 IARERE 707
+ ERE
Sbjct: 256 LEWERE 261
Score = 52.4 bits (124), Expect = 2e-06
Identities = 33/94 (35%), Positives = 54/94 (57%), Gaps = 4/94 (4%)
Query: 573 RGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELR 632
R R E+ + E+ L+++R + R++ + E+++ Q E R +R R+ + R
Sbjct: 173 RERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQER 232
Query: 633 RRREIAERERRERERIRIIREREERERLQRERER 666
R E ERER+ERER +E+ ERE+L+ ERER
Sbjct: 233 ERLERLERERQERER----QEQLEREQLEWERER 262
Score = 41.2 bits (95), Expect = 0.005
Identities = 44/188 (23%), Positives = 80/188 (42%), Gaps = 10/188 (5%)
Query: 648 IRIIREREERERLQRERERLEIERQKLERERMERERLERERIRI-EQERRKEAERIARER 706
+ ++ +E L R+ +L + Q +E LE +R ++ EQ+R+KE ER ER
Sbjct: 108 LEVLNSQETGPTLPRQNSQLPAQVQN----GPSQEELEIQRRQLQEQQRQKELERERLER 163
Query: 707 EELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQN 766
E + R++ L E+ +R L+R R + + ++ L+ R RQ+
Sbjct: 164 ERMERER--LERERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQER 221
Query: 767 RFNDFDHRERGRFPESSAVQSSSFERRDRFV-GQSEGKKARPTARREDPSFERYPKN--F 823
+ R+ E + ER+++ Q E ++ R + P+ P N
Sbjct: 222 LDRERQERQERERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVL 281
Query: 824 SDSRRNEP 831
DS +EP
Sbjct: 282 GDSSASEP 289
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 82.4 bits (202), Expect = 2e-15
Identities = 99/380 (26%), Positives = 161/380 (42%), Gaps = 49/380 (12%)
Query: 483 GDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSE---- 538
GD+K++ KT + +E+KR E+ EK E K K + +D K D+ G+ +
Sbjct: 2 GDEKDSW--KVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCME 59
Query: 539 -SIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDK 597
+I+ S ++ S + G K P + R EK+H R EK + +K R
Sbjct: 60 ITIRNSPYRREDSMEDRGEEDDSLAIKP----PQQMSRKEKVHHRKDEKRK---EKCRHH 112
Query: 598 DYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREER 657
+ E K R++E E RR +R RE ++ RRE ER + R R
Sbjct: 113 SHSA------EGGKHARVKER----EHERR----KRHREEQDKARREWERQK--RREMAR 156
Query: 658 ERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIARE-REELRRQQQQL 716
E +RER+RLE +K ERER RE+ + +R + E+ERR E R RE R E+ + +
Sbjct: 157 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTM 216
Query: 717 RYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDF----D 772
R + + H P ++ L D R + +++ +D D
Sbjct: 217 REDYSDKVK------ASHWSRSPPRPPRERFELG-DGRKPVKEEKMEERDLLSDLQDISD 269
Query: 773 HRERGRFPESSAVQS---SSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSD---- 825
+ ESS+ +S S E + + EG + + E+ E + S+
Sbjct: 270 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 329
Query: 826 SRRNEPPPPRNELRESDRRE 845
S ++ E+ E + RE
Sbjct: 330 SEQSAEEVSEEEMSEDEERE 349
Score = 53.1 bits (126), Expect = 1e-06
Identities = 80/397 (20%), Positives = 152/397 (38%), Gaps = 73/397 (18%)
Query: 582 RSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERE 641
R +++E+A + + ++ D R + + ++E LR+H + +R + RRE + +
Sbjct: 23 RKEQEEKAEIKRLKNSDDRDSKR---DSLEEGELRDHCMEIT-IRNSPY---RREDSMED 75
Query: 642 RRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAER 701
R E + I+ ++ R ++ R + +R +E+ E + + + +E ER
Sbjct: 76 RGEEDDSLAIKPPQQMSRKEKVHHRKDEKR----KEKCRHHSHSAEGGKHARVKEREHER 131
Query: 702 IAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDY 761
R REE + +++ +E++KR + R +H R
Sbjct: 132 RKRHREEQDKARRE--WERQKRREMAR----EHSR------------------------- 160
Query: 762 SRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERYPK 821
R+++R + R+R R + Q E+++R E +K R R +
Sbjct: 161 -RERDRLEQLE-RKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRE 218
Query: 822 NFSDS------RRNEPPPPRNELRESD-RREVRGERDERRTVIIHDRPDITHPRHPREAG 874
++SD R+ P PPR D R+ V+ E+ E R ++ D DI+ +
Sbjct: 219 DYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERD-LLSDLQDISDSERKTSSA 277
Query: 875 PNPSRPTSWKSE---------------GSMSTDKRETRVERPERSGREVSGHSVRGAPPG 919
+ S + SE S ++ E E E +G S + A
Sbjct: 278 ESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEV 337
Query: 920 NRSSASGYGSREGDRGVIT------DRGGGSQHYPEE 950
+ S RE + ++ DR G EE
Sbjct: 338 SEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 374
Score = 44.7 bits (104), Expect = 5e-04
Identities = 46/225 (20%), Positives = 99/225 (44%), Gaps = 42/225 (18%)
Query: 464 PSKKEMKKENDEKSSSR--SSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKI 521
P K+E +E D S + S ++K +S SS ++ EE+ E+ E++E +++
Sbjct: 249 PVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 308
Query: 522 EGKDEK----------NDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPS 571
E ++E+ N AS Q++E + + E + ++ H++++ ++
Sbjct: 309 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES-------- 360
Query: 572 RRGRYEKIHGRSKEKE--------RASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFE 623
R+++ G S+E E ++S + D +LP E +Q L ++L +
Sbjct: 361 ---RFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIE--LKQELPKYLPALQ 415
Query: 624 RLRRAMELRRRREIAE---------RERRERERIRIIREREERER 659
R E + I E ++++ E + + R + E+E+
Sbjct: 416 GCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEK 460
Score = 43.5 bits (101), Expect = 0.001
Identities = 39/133 (29%), Positives = 65/133 (48%), Gaps = 19/133 (14%)
Query: 93 SGDASVEDDAFIKDCELENQEAHEQDG--NDELKDSEEFGENEEENVHSKELLSAEENKR 150
S ++S + + E E +E E++G ++E ++ EE E EEE S ++E++
Sbjct: 276 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQS-- 333
Query: 151 AHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSK 210
A E+ E E ED E+E+ E+ + E D GE EE E+++ G+GT
Sbjct: 334 AEEVSEEEMSEDEEREN-ENHLLVVPESRFD----RDSGESEEAEEEV---GEGT----- 380
Query: 211 PLPSEGSLAEADH 223
P +L E D+
Sbjct: 381 --PQSSALTEGDY 391
Score = 42.4 bits (98), Expect = 0.002
Identities = 56/322 (17%), Positives = 120/322 (37%), Gaps = 46/322 (14%)
Query: 51 RLKQAIEEEGGDPDNIELTVSTDTPNKKPT---KGKGKKHEADELSGDASVEDDAFIKDC 107
R + ++E+ G + D++ + K+ K + +K + S A A +K+
Sbjct: 68 RREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGKHARVKER 127
Query: 108 ELENQEAHEQDGNDELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKED 167
E E ++ H ++ + ++ E E HS+ E + +E +E++
Sbjct: 128 EHERRKRHREEQDKARREWERQKRREMAREHSRR--------------ERDRLEQLERKR 173
Query: 168 IESQEIEAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHE 227
+++ Q+ E + E E ++ + +EVS AH
Sbjct: 174 ERERKMREQQKEQ-----REQKERERRAEERRKEREARREVS---------------AH- 212
Query: 228 EMEAHTTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIA 287
H T++E D + + + + +L + K VK E I+
Sbjct: 213 ----HRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDIS 268
Query: 288 QSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGA 347
S K S +A G +E+ + E+E E +E ++E++ ++ TG+
Sbjct: 269 DSERKTSSAESSSAESGSGSEEE----EEEEEEEEEEGSTSEESEEEEEEEEEEEEETGS 324
Query: 348 SGQAKSSSKESKDSKTSSKDDK 369
+ + S + S+ +D+
Sbjct: 325 NSEEASEQSAEEVSEEEMSEDE 346
Score = 37.7 bits (86), Expect = 0.056
Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 11/110 (10%)
Query: 133 EEENVHSKELLS-------AEENKRAHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLT 185
+EE + ++LLS +E + E AE E+E+ E +E E +EG
Sbjct: 251 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEE-EEEEGSTSEESE 309
Query: 186 AQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTV 235
++ EEEE E++ +G ++E S+ E S E E E H V
Sbjct: 310 EEEEEEEEEEEE---TGSNSEEASEQSAEEVSEEEMSEDEERENENHLLV 356
Score = 36.2 bits (82), Expect = 0.16
Identities = 50/242 (20%), Positives = 81/242 (33%), Gaps = 53/242 (21%)
Query: 465 SKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGK 524
+++ ++E D +++ K Q K+ E+R+ E+ +++E++ +
Sbjct: 155 AREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHR 214
Query: 525 DEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSK 584
+ D S+ +K S S+SP RP R R+E GR
Sbjct: 215 TMRED------YSDKVKASH-----WSRSPP-------------RPPRE-RFELGDGRKP 249
Query: 585 EKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRR--------AMELRRRRE 636
KE EKM+E+ L L R + E E
Sbjct: 250 VKE--------------------EKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 289
Query: 637 IAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERR 696
E E E E E E E + E E E E E + E + ++ER
Sbjct: 290 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 349
Query: 697 KE 698
E
Sbjct: 350 NE 351
Score = 30.8 bits (68), Expect = 6.9
Identities = 26/135 (19%), Positives = 55/135 (40%), Gaps = 2/135 (1%)
Query: 117 QDGNDELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQ 176
+D +D++K S EL + + ++ E + + D++ DI E +
Sbjct: 218 EDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ--DISDSERKTS 275
Query: 177 EGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVK 236
E + + EEEE E++ T E S+ E E + ++ E + + +
Sbjct: 276 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 335
Query: 237 EAEDDNISVTIQAED 251
E ++ +S + E+
Sbjct: 336 EVSEEEMSEDEEREN 350
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.125 0.341
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,296,674
Number of Sequences: 37866
Number of extensions: 2331950
Number of successful extensions: 50727
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1049
Number of HSP's successfully gapped in prelim test: 1478
Number of HSP's that attempted gapping in prelim test: 11772
Number of HSP's gapped (non-prelim): 15564
length of query: 1034
length of database: 18,247,518
effective HSP length: 112
effective length of query: 922
effective length of database: 14,006,526
effective search space: 12914016972
effective search space used: 12914016972
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.