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Search of human proteins with 62912464
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62912464 complement component 4 binding protein, beta chain
isoform 1 precursor [Homo sapiens]
(252 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62912468 complement component 4 binding protein, beta chain i... 541 e-154
gi|62912464 complement component 4 binding protein, beta chain i... 541 e-154
gi|4502505 complement component 4 binding protein, beta chain is... 541 e-154
gi|62912466 complement component 4 binding protein, beta chain i... 535 e-152
gi|62912462 complement component 4 binding protein, beta chain i... 535 e-152
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] 123 2e-28
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap... 103 1e-22
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa... 103 1e-22
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap... 103 1e-22
gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens] 100 2e-21
gi|148886654 polydom [Homo sapiens] 97 2e-20
gi|54792123 complement component (3d/Epstein Barr virus) recepto... 91 1e-18
gi|42544177 complement component (3d/Epstein Barr virus) recepto... 90 2e-18
gi|67782358 complement factor B preproprotein [Homo sapiens] 88 6e-18
gi|187960042 selectin E precursor [Homo sapiens] 87 2e-17
gi|32261332 seizure related 6 homolog (mouse)-like precursor [Ho... 84 1e-16
gi|157419154 selectin P precursor [Homo sapiens] 80 1e-15
gi|148922949 complement component (3b/4b) receptor 1-like [Homo ... 80 2e-15
gi|166235138 seizure related 6 homolog (mouse)-like 2 isoform 3 ... 78 8e-15
gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2 ... 78 8e-15
gi|86793109 complement receptor 1 isoform S precursor [Homo sapi... 77 1e-14
gi|86793036 complement receptor 1 isoform F precursor [Homo sapi... 77 1e-14
gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4 ... 77 1e-14
gi|6912612 seizure related 6 homolog (mouse)-like 2 isoform 1 [H... 77 1e-14
gi|14550407 complement component 2 isoform 1 preproprotein [Homo... 73 2e-13
gi|4502503 complement component 4 binding protein, alpha chain p... 71 8e-13
gi|168693643 decay accelerating factor for complement isoform 2 ... 68 7e-12
gi|10835143 decay accelerating factor for complement isoform 1 p... 68 7e-12
gi|148839346 seizure related 6 homolog isoform 2 [Homo sapiens] 68 9e-12
gi|148839280 seizure related 6 homolog isoform 1 [Homo sapiens] 68 9e-12
>gi|62912468 complement component 4 binding protein, beta chain
isoform 1 precursor [Homo sapiens]
Length = 252
Score = 541 bits (1394), Expect = e-154
Identities = 252/252 (100%), Positives = 252/252 (100%)
Query: 1 MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT 60
MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT
Sbjct: 1 MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT 60
Query: 61 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ 120
LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ
Sbjct: 61 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ 120
Query: 121 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV 180
CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV
Sbjct: 121 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV 180
Query: 181 DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL 240
DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL
Sbjct: 181 DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL 240
Query: 241 ELKKAELKAKLL 252
ELKKAELKAKLL
Sbjct: 241 ELKKAELKAKLL 252
>gi|62912464 complement component 4 binding protein, beta chain
isoform 1 precursor [Homo sapiens]
Length = 252
Score = 541 bits (1394), Expect = e-154
Identities = 252/252 (100%), Positives = 252/252 (100%)
Query: 1 MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT 60
MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT
Sbjct: 1 MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT 60
Query: 61 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ 120
LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ
Sbjct: 61 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ 120
Query: 121 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV 180
CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV
Sbjct: 121 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV 180
Query: 181 DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL 240
DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL
Sbjct: 181 DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL 240
Query: 241 ELKKAELKAKLL 252
ELKKAELKAKLL
Sbjct: 241 ELKKAELKAKLL 252
>gi|4502505 complement component 4 binding protein, beta chain
isoform 1 precursor [Homo sapiens]
Length = 252
Score = 541 bits (1394), Expect = e-154
Identities = 252/252 (100%), Positives = 252/252 (100%)
Query: 1 MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT 60
MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT
Sbjct: 1 MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT 60
Query: 61 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ 120
LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ
Sbjct: 61 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ 120
Query: 121 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV 180
CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV
Sbjct: 121 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV 180
Query: 181 DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL 240
DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL
Sbjct: 181 DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL 240
Query: 241 ELKKAELKAKLL 252
ELKKAELKAKLL
Sbjct: 241 ELKKAELKAKLL 252
>gi|62912466 complement component 4 binding protein, beta chain
isoform 2 precursor [Homo sapiens]
Length = 251
Score = 535 bits (1378), Expect = e-152
Identities = 251/252 (99%), Positives = 251/252 (99%), Gaps = 1/252 (0%)
Query: 1 MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT 60
MFFWCACCLMVAWRVSASD EHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT
Sbjct: 1 MFFWCACCLMVAWRVSASD-EHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT 59
Query: 61 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ 120
LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ
Sbjct: 60 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ 119
Query: 121 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV 180
CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV
Sbjct: 120 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV 179
Query: 181 DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL 240
DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL
Sbjct: 180 DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL 239
Query: 241 ELKKAELKAKLL 252
ELKKAELKAKLL
Sbjct: 240 ELKKAELKAKLL 251
>gi|62912462 complement component 4 binding protein, beta chain
isoform 2 precursor [Homo sapiens]
Length = 251
Score = 535 bits (1378), Expect = e-152
Identities = 251/252 (99%), Positives = 251/252 (99%), Gaps = 1/252 (0%)
Query: 1 MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT 60
MFFWCACCLMVAWRVSASD EHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT
Sbjct: 1 MFFWCACCLMVAWRVSASD-EHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKT 59
Query: 61 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ 120
LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ
Sbjct: 60 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQ 119
Query: 121 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV 180
CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV
Sbjct: 120 CLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV 179
Query: 181 DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL 240
DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL
Sbjct: 180 DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSL 239
Query: 241 ELKKAELKAKLL 252
ELKKAELKAKLL
Sbjct: 240 ELKKAELKAKLL 251
>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
Length = 3565
Score = 123 bits (308), Expect = 2e-28
Identities = 66/183 (36%), Positives = 93/183 (50%), Gaps = 7/183 (3%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHC--PDPVLVNGEFSSSGPVNVSDKIT 104
+ C GY LVG C A+ W + T C GHC PDP+ VNG S G + D +
Sbjct: 2647 FTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPI-VNGHISGDG-FSYRDTVV 2704
Query: 105 FMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYY 164
+ CN + L G++ CL+DH W+ P+C C PGNP HG+ G+ F L +++
Sbjct: 2705 YQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFT 2764
Query: 165 CEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFM 223
C Y L GV QC +G+WSS LP C+++ + E A+ Q+ N E+ E M
Sbjct: 2765 CNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQ--NFPESFEYGM 2822
Query: 224 QQL 226
L
Sbjct: 2823 SIL 2825
Score = 83.6 bits (205), Expect = 2e-16
Identities = 48/157 (30%), Positives = 73/157 (46%), Gaps = 14/157 (8%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-----VLVNGEFSSSGPVNVSD 101
Y C KG++L+G L C A+ WD + +C C P ++ GE + G V
Sbjct: 2826 YHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGAV---- 2881
Query: 102 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRD---CDPPGNPVHGYFEGNNFTLG 158
+ + C L G++ C ED W+ P C + C PG P HG G++F
Sbjct: 2882 -VHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTK 2940
Query: 159 STISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 194
S + + CE + L G E+ C ++G WS PVC+ +
Sbjct: 2941 SLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAV 2977
Score = 79.3 bits (194), Expect = 3e-15
Identities = 43/151 (28%), Positives = 64/151 (42%), Gaps = 6/151 (3%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLV-----NGEFSSSGPVNVSD 101
+ C GY L G C ++ +W + CR+ +C DP V +G+ +
Sbjct: 2763 FTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGM 2822
Query: 102 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTI 161
I + C + L GS+ C+ + W P C + C PG P + G FT G+ +
Sbjct: 2823 SILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGAVV 2882
Query: 162 SYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 191
Y C L+G + C D WS ALP C
Sbjct: 2883 HYSCRGSESLIGNDTRVCQEDSHWSGALPHC 2913
Score = 75.1 bits (183), Expect = 5e-14
Identities = 45/158 (28%), Positives = 63/158 (39%), Gaps = 5/158 (3%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-VLVNGEFSSSGPVNVSDKITF 105
+ C G+ L G C + W C C +P NG SS + S + +
Sbjct: 2945 FSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIY 3004
Query: 106 MCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 165
C + Y G C + TW P C C PG +G G +FT T+SY C
Sbjct: 3005 ACWEGYKTSGLMTRHCTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQC 3064
Query: 166 EDRYYLVGVQEQ--QCV-DGEWSSALPVCKLIQEAPKP 200
Y + V +C DG W+ + PVCK + P+P
Sbjct: 3065 NPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVL-CPQP 3101
Score = 74.7 bits (182), Expect = 7e-14
Identities = 50/190 (26%), Positives = 68/190 (35%), Gaps = 5/190 (2%)
Query: 7 CCLMVAWRVSASDAE--HCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHL--VGKKTLF 62
C W +A D C + + N I + +Y C GY + V T+
Sbjct: 3020 CTANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIR 3079
Query: 63 CNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCL 122
C W+ + C+ CP P V I++ C D Y L S C
Sbjct: 3080 CTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCE 3139
Query: 123 EDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VD 181
W P C C PG P G G +FT S + + C+ + LVG + C D
Sbjct: 3140 GRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQAD 3199
Query: 182 GEWSSALPVC 191
G WS P C
Sbjct: 3200 GTWSGIQPTC 3209
Score = 67.4 bits (163), Expect = 1e-11
Identities = 38/153 (24%), Positives = 58/153 (37%), Gaps = 5/153 (3%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTEC---RLGHCPDPVLVNGEFSSSGPVNVSDKI 103
Y C L+G T C W C G C DP +
Sbjct: 2884 YSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKSLL 2943
Query: 104 TFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYF-EGNNFTLGSTIS 162
F C + L+GS CL + +W+ P+C++ C PG P +G + S++
Sbjct: 2944 RFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVI 3003
Query: 163 YYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 194
Y C + Y G+ + C +G W+ P C +I
Sbjct: 3004 YACWEGYKTSGLMTRHCTANGTWTGTAPDCTII 3036
Score = 66.2 bits (160), Expect = 3e-11
Identities = 44/153 (28%), Positives = 60/153 (39%), Gaps = 7/153 (4%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTEC---RLGHCPDPVLVN-GEFSSSGPVNVSDK 102
+ C + LVG C A W C CPDP + G +SS V
Sbjct: 3180 FQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGST 3239
Query: 103 ITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNF-TLGSTI 161
+ F C Y ++GS CL + TW+ C C P P H + T G T+
Sbjct: 3240 VFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTL 3299
Query: 162 SYYCEDRYYLVGVQEQQC--VDGEWSSALPVCK 192
Y C ++L G E + D +W+ PVCK
Sbjct: 3300 VYTCHPGFFLAGGSEHRTCKADMKWTGKSPVCK 3332
Score = 58.5 bits (140), Expect = 5e-09
Identities = 38/126 (30%), Positives = 56/126 (44%), Gaps = 13/126 (10%)
Query: 76 CRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED----HTWAPPF 131
C L H L NG + V K+ + C Y + G + + C + + W
Sbjct: 2433 CSLTH----PLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLT 2488
Query: 132 PICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV---DGEWSS-- 186
P+C++ C P +P +G F GN FTL S + Y C + + L Q+ V DG WS+
Sbjct: 2489 PLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKG 2548
Query: 187 ALPVCK 192
P CK
Sbjct: 2549 KPPTCK 2554
Score = 51.2 bits (121), Expect = 8e-07
Identities = 42/165 (25%), Positives = 72/165 (43%), Gaps = 18/165 (10%)
Query: 47 YVCIKGYHLVGKKTLFCNASK----EWDNTTTECRLGHCPDPVLV-NGEFSSSGPVNVSD 101
Y C GY +VG C + +WD+ T C+ C P NG F+ + +
Sbjct: 2458 YFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGN-EFTLDS 2516
Query: 102 KITFMCNDHYILKGSNRSQ--CLEDHTWA----PPF--PI-CKSRDCDPPGNPVHGYFEG 152
K+ + C++ + L+ S ++ C ED W+ PP P+ C S + + + G
Sbjct: 2517 KVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSG 2576
Query: 153 NNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWS--SALPVCKLI 194
+ G+ + C YYL G + +C +G W+ P C++I
Sbjct: 2577 SLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVI 2621
Score = 48.1 bits (113), Expect = 7e-06
Identities = 31/96 (32%), Positives = 38/96 (39%), Gaps = 12/96 (12%)
Query: 49 CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITF--- 105
C KGYH+ G T C A+ W TEC C P E + V D TF
Sbjct: 3244 CRKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQP-----ETPAHADVRAIDLPTFGYT 3298
Query: 106 ---MCNDHYILK-GSNRSQCLEDHTWAPPFPICKSR 137
C+ + L GS C D W P+CKS+
Sbjct: 3299 LVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVCKSK 3334
Score = 47.4 bits (111), Expect = 1e-05
Identities = 46/183 (25%), Positives = 68/183 (37%), Gaps = 20/183 (10%)
Query: 24 PELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKK--TLFCNASKEWDNT--TTECRLG 79
PE P N F E Y C +G+ L + T C W N C+
Sbjct: 2499 PESP--GNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPV 2556
Query: 80 HCPDPVLVNGEFSS-------SGPVN-VSDKITFMCNDHYILKGSNRSQCLEDHTW--AP 129
CP + + S SG +N ++ C+ Y L+G +C + TW
Sbjct: 2557 ACPS---IEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGD 2613
Query: 130 PFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSAL 188
P C+ C P +G G G+T + C Y LVG ++C+ +G WS +
Sbjct: 2614 ERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSE 2673
Query: 189 PVC 191
C
Sbjct: 2674 TRC 2676
Score = 44.7 bits (104), Expect = 8e-05
Identities = 22/60 (36%), Positives = 36/60 (60%), Gaps = 5/60 (8%)
Query: 138 DCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLV-GVQEQQCV--DGE--WSSALPVCK 192
+C PG P++G G+ F LGS++S++C+D + G + C+ DG WSS +P C+
Sbjct: 697 ECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCE 756
Score = 44.3 bits (103), Expect = 1e-04
Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 5/58 (8%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG-----EWSSALPVC 191
C PGN ++G G +F LGSTI+Y C+ Y ++ CV G W LP C
Sbjct: 1565 CFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSC 1622
Score = 42.0 bits (97), Expect = 5e-04
Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 5/64 (7%)
Query: 81 CPDP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED----HTWAPPFPICK 135
CPDP + NG + S V + F C D+Y+L+GS C W+ PIC+
Sbjct: 349 CPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICR 408
Query: 136 SRDC 139
+R C
Sbjct: 409 ARTC 412
Score = 41.6 bits (96), Expect = 7e-04
Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
Query: 135 KSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVC 191
+S C PG PV+G+ G +F + ST+++ C+ Y L + C + +W+ ALP C
Sbjct: 870 ESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSC 927
Score = 38.1 bits (87), Expect = 0.007
Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 6/60 (10%)
Query: 139 CDPPGNPVHGYFEGNNFT-LGSTISYYCEDRYYLVGVQEQQC-----VDGEWSSALPVCK 192
C PG P +G G++F+ +G+ + + CED Y L G + C WS P+C+
Sbjct: 349 CPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICR 408
Score = 38.1 bits (87), Expect = 0.007
Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 191
C PG P +G G++F G T+++ C + LVG + C + +WS P C
Sbjct: 528 CGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSC 581
Score = 36.6 bits (83), Expect = 0.021
Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVC 191
CD PG P G +F +G ++++ C Y L G + C+ G WS+ LP C
Sbjct: 1046 CDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRC 1101
Score = 35.4 bits (80), Expect = 0.048
Identities = 18/67 (26%), Positives = 24/67 (35%), Gaps = 5/67 (7%)
Query: 131 FPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV-----DGEWS 185
+ + S C PG + G G F +G I Y C Y L G C+ W
Sbjct: 137 YEVLPSHTCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWD 196
Query: 186 SALPVCK 192
P C+
Sbjct: 197 FPAPFCR 203
Score = 35.4 bits (80), Expect = 0.048
Identities = 26/95 (27%), Positives = 38/95 (40%), Gaps = 7/95 (7%)
Query: 72 TTTECRLGHCPDPVLVNGEFSSSGPVNVSDKIT-FMCNDHYILKGSNRSQCL--EDHTWA 128
T T L C DP + N + + +D + + CN Y + GSN CL + W
Sbjct: 1209 TYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWD 1268
Query: 129 PPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISY 163
P P C + +C G +H G + G Y
Sbjct: 1269 KPLPSCIA-EC---GGQIHAATSGRILSPGYPAPY 1299
Score = 34.3 bits (77), Expect = 0.11
Identities = 16/59 (27%), Positives = 25/59 (42%), Gaps = 2/59 (3%)
Query: 78 LGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED--HTWAPPFPIC 134
L C +P L + V+D ++F C Y L+G + C+ W P P+C
Sbjct: 1913 LAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLC 1971
Score = 33.9 bits (76), Expect = 0.14
Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 4/57 (7%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE----WSSALPVC 191
C+ PG P +G G++ G T+++ C+ Y L G + CV W P C
Sbjct: 1392 CNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC 1448
Score = 33.9 bits (76), Expect = 0.14
Identities = 18/59 (30%), Positives = 25/59 (42%), Gaps = 2/59 (3%)
Query: 78 LGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLE--DHTWAPPFPIC 134
L +CPDP + + +V ++F C YIL G C + W PFP C
Sbjct: 2085 LQNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRC 2143
Score = 32.7 bits (73), Expect = 0.31
Identities = 15/62 (24%), Positives = 27/62 (43%), Gaps = 2/62 (3%)
Query: 17 ASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFC--NASKEWDNTTT 74
A + ++CP+ PP N + + ++ C GY L+G L C ++ W+
Sbjct: 2082 AYELQNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFP 2141
Query: 75 EC 76
C
Sbjct: 2142 RC 2143
Score = 32.7 bits (73), Expect = 0.31
Identities = 15/58 (25%), Positives = 28/58 (48%), Gaps = 3/58 (5%)
Query: 137 RDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVC 191
++C P +GY +++++G ++S+ C Y L+G C G W+ P C
Sbjct: 2086 QNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRC 2143
Score = 32.3 bits (72), Expect = 0.40
Identities = 21/78 (26%), Positives = 30/78 (38%), Gaps = 10/78 (12%)
Query: 81 CPDP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDC 139
C DP + VNG G + +TF C+ Y L C +H W P C +
Sbjct: 874 CLDPGIPVNGH-RHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDAL-- 930
Query: 140 DPPGNPVHGYFEGNNFTL 157
GY +G + T+
Sbjct: 931 ------CGGYIQGKSGTV 942
Score = 31.6 bits (70), Expect = 0.69
Identities = 20/65 (30%), Positives = 27/65 (41%), Gaps = 2/65 (3%)
Query: 72 TTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED--HTWAP 129
T +E L C DP + V D +TF C Y L+G+ + CL W+
Sbjct: 1037 TFSEYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSA 1096
Query: 130 PFPIC 134
P P C
Sbjct: 1097 PLPRC 1101
Score = 29.6 bits (65), Expect = 2.6
Identities = 15/57 (26%), Positives = 23/57 (40%), Gaps = 3/57 (5%)
Query: 81 CPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHT---WAPPFPIC 134
C DP + D +TF C+ Y L+G + C++ + W P P C
Sbjct: 1392 CNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC 1448
Score = 29.3 bits (64), Expect = 3.4
Identities = 14/43 (32%), Positives = 21/43 (48%), Gaps = 4/43 (9%)
Query: 98 NVSDKITFMCNDHYILKGSNRSQCL----EDHTWAPPFPICKS 136
N+ DKI + C YIL+G C+ +W P P C++
Sbjct: 162 NIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRA 204
Score = 27.7 bits (60), Expect = 9.9
Identities = 8/31 (25%), Positives = 15/31 (48%)
Query: 46 TYVCIKGYHLVGKKTLFCNASKEWDNTTTEC 76
T+ C + LVG++ + C + +W C
Sbjct: 551 TFECPAAFELVGERVITCQQNNQWSGNKPSC 581
Score = 27.7 bits (60), Expect = 9.9
Identities = 16/61 (26%), Positives = 25/61 (40%), Gaps = 5/61 (8%)
Query: 137 RDCDPPGNPVHGYF--EGNNFTLGSTISYYCEDRYYLVGVQEQQC---VDGEWSSALPVC 191
+ C PP E ++F +G + Y C Y LVG C ++ +LP C
Sbjct: 2257 KKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTC 2316
Query: 192 K 192
+
Sbjct: 2317 E 2317
>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sapiens]
Length = 3667
Score = 103 bits (257), Expect = 1e-22
Identities = 52/174 (29%), Positives = 80/174 (45%), Gaps = 3/174 (1%)
Query: 23 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 82
C ELP N + + + C G+ LVG C +S W + T C GHC
Sbjct: 2719 CGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCG 2778
Query: 83 DP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 141
P ++VNG+ D + + CN + L GS+ C +DH W+ P C C
Sbjct: 2779 IPELIVNGQVIGEN-YGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGH 2837
Query: 142 PGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 194
PG+P++G GN F +++ C Y + G + QC + +WS P+CK++
Sbjct: 2838 PGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVV 2891
Score = 95.9 bits (237), Expect = 3e-20
Identities = 54/173 (31%), Positives = 78/173 (45%), Gaps = 20/173 (11%)
Query: 39 VEGQILG---------TYVCIKGYHLVGKKTLFCNASKEWDNTTTEC---RLGHCPDPVL 86
V GQ++G Y C G+ L+G C W C GH P+
Sbjct: 2784 VNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIY 2843
Query: 87 VNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPV 146
G S +G N +D +TF CN Y+++G ++QC + W+ P P+CK +C PG P
Sbjct: 2844 --GRTSGNG-FNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPA 2900
Query: 147 H----GYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 194
+ E NFT G+ + Y C Y+L G C +G+W LP C +I
Sbjct: 2901 NSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMI 2953
Score = 91.7 bits (226), Expect = 6e-19
Identities = 48/165 (29%), Positives = 74/165 (44%), Gaps = 4/165 (2%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-VLVNGEFSSSGPVNVSDKITF 105
Y C GY L G + C A+ W EC+ C +P NG+ S + +
Sbjct: 3040 YACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIY 3099
Query: 106 MCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 165
C + YIL G + QC + TW+ P C C PG P +G G+++ +G +SY C
Sbjct: 3100 SCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMC 3159
Query: 166 EDRY--YLVGVQEQQC-VDGEWSSALPVCKLIQEAPKPECEKALL 207
+ Y L G + + C ++G WS +P C+ + P+ L
Sbjct: 3160 QPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRL 3204
Score = 86.7 bits (213), Expect = 2e-17
Identities = 46/151 (30%), Positives = 70/151 (46%), Gaps = 5/151 (3%)
Query: 46 TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-VLVNGEFSSS---GPVNVSD 101
T+ C GY + G C A+++W + C++ +C DP + N + S G
Sbjct: 2858 TFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGT 2917
Query: 102 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTI 161
+ + CN Y L GS+ C + W P P C DC PG P + G +T GST+
Sbjct: 2918 VVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTV 2977
Query: 162 SYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 191
Y C + L+G + C ++G WS + P C
Sbjct: 2978 HYSCTGKRSLLGQSSRTCQLNGHWSGSQPHC 3008
Score = 84.0 bits (206), Expect = 1e-16
Identities = 45/153 (29%), Positives = 65/153 (42%), Gaps = 4/153 (2%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFM 106
Y C GY L G L C + +WD EC + C P + S + +
Sbjct: 2921 YDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYS 2980
Query: 107 CNDHYILKGSNRSQCLEDHTWAPPFPICK---SRDCDPPGNPVHGYFEGNNFTLGSTISY 163
C L G + C + W+ P C + C PG P HG + +NF ST+ Y
Sbjct: 2981 CTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRY 3040
Query: 164 YCEDRYYLVGVQEQQCV-DGEWSSALPVCKLIQ 195
C+ Y L G +E+ C+ +G W+ P CK +Q
Sbjct: 3041 ACDTGYILHGSEERTCLANGSWTGRQPECKAVQ 3073
Score = 78.6 bits (192), Expect = 5e-15
Identities = 52/192 (27%), Positives = 78/192 (40%), Gaps = 15/192 (7%)
Query: 8 CLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASK 67
C+M+ D H P +PP N++ ++ Y C L+G+ + C +
Sbjct: 2950 CIMI-------DCGH-PGVPP--NAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNG 2999
Query: 68 EWDNTTTECR---LGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED 124
W + C G C DP + + C+ YIL GS CL +
Sbjct: 3000 HWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLAN 3059
Query: 125 HTWAPPFPICKSRDCDPPGNPVHG-YFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDG 182
+W P CK+ C PG +G F + T S++ Y C + Y L G +QC +G
Sbjct: 3060 GSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANG 3119
Query: 183 EWSSALPVCKLI 194
WS LP C +I
Sbjct: 3120 TWSGTLPNCTII 3131
Score = 78.6 bits (192), Expect = 5e-15
Identities = 49/175 (28%), Positives = 73/175 (41%), Gaps = 7/175 (4%)
Query: 23 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 82
CP P + N + +Y+C GY L L C + W +C C
Sbjct: 3193 CPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCG 3252
Query: 83 DP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPIC---KSRD 138
DP + G+ + S+ ++F CN +IL GS+ C D TW+ P C
Sbjct: 3253 DPGIPAQGKREGKSFIYQSE-VSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTS 3311
Query: 139 CDPPGNPVHGYFEGN-NFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVC 191
C+ PG P HG F +GS + ++C+ + L G + C+ D WS P C
Sbjct: 3312 CENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPEC 3366
Score = 76.6 bits (187), Expect = 2e-14
Identities = 48/172 (27%), Positives = 72/172 (41%), Gaps = 6/172 (3%)
Query: 46 TYVCIKGY--HLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKI 103
+Y+C GY L G + C + W CR CP P ++ + I
Sbjct: 3156 SYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSI 3215
Query: 104 TFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISY 163
+++C+ Y L C+ + TW+ P C + C PG P G EG +F S +S+
Sbjct: 3216 SYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSF 3275
Query: 164 YCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAPKPECEKALLAFQESKN 214
C + LVG + C DG WS + P C E + CE + S+N
Sbjct: 3276 SCNFPFILVGSSTRICQADGTWSGSSPHC---IEPTQTSCENPGVPRHGSQN 3324
Score = 73.2 bits (178), Expect = 2e-13
Identities = 45/166 (27%), Positives = 74/166 (44%), Gaps = 11/166 (6%)
Query: 46 TYVCIKGYHLVGKKTLFCNASKEWDNTTTEC---RLGHCPDP-VLVNGEFSSSGPVNVSD 101
++ C + LVG T C A W ++ C C +P V +G +++ V
Sbjct: 3274 SFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGS 3333
Query: 102 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNF-TLGST 160
+ F C ++L+GS CL D TW+ P C C P P H G + + G T
Sbjct: 3334 VVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYT 3393
Query: 161 ISYYCEDRYYLVGVQEQQCV--DGEWSSALPVC----KLIQEAPKP 200
+ Y C+ ++L G E + D W+ +P+C K++ + P+P
Sbjct: 3394 LIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRP 3439
Score = 57.8 bits (138), Expect = 9e-09
Identities = 44/158 (27%), Positives = 66/158 (41%), Gaps = 12/158 (7%)
Query: 46 TYVCIKGYHLVGKK--TLFCNASKEWDN--TTTECRLGHCPDP---VLVNGEFS--SSGP 96
TY C GY L K+ T C + W N T C + CP +L +G + +
Sbjct: 2615 TYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSH 2674
Query: 97 VNVSDKITFMCNDHYILKGSNRSQCLEDHTWA--PPFPICKSRDCDPPGNPVHGYFEGNN 154
K+ F C+ Y G +CL + TW+ P C+ C P +G G
Sbjct: 2675 YEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQ 2734
Query: 155 FTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVC 191
+ GST + C+ + LVG ++C+ G WS + C
Sbjct: 2735 TSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC 2772
Score = 57.4 bits (137), Expect = 1e-08
Identities = 50/197 (25%), Positives = 83/197 (42%), Gaps = 23/197 (11%)
Query: 24 PELPPVDNSIFVAKEVEGQILGT--YVCIKGYHLVGKKTLFCNASK----EWDNTTTECR 77
PE PP ++ + GQ+ + C +G+ LVGK + C S WD C+
Sbjct: 2532 PESPPHG---YIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2588
Query: 78 LGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYIL--KGSNRSQCLEDHTWA--PPFPI 133
C P + V ++T+ CND Y L K + C D TW+ P
Sbjct: 2589 AISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPR 2648
Query: 134 CKSRDCDPPGNPV--HGYF---EGNNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWS-- 185
C C + + HG + G+++ + + + C+ Y+ +G +C+ +G WS
Sbjct: 2649 CVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWR 2708
Query: 186 SALPVCKLIQ--EAPKP 200
+ P C++I E P P
Sbjct: 2709 NERPYCQIISCGELPTP 2725
Score = 48.9 bits (115), Expect = 4e-06
Identities = 23/58 (39%), Positives = 33/58 (56%), Gaps = 5/58 (8%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE-----WSSALPVC 191
C PGN ++G G ++ LGST++YYC+ Y L G C+ G+ W+ ALP C
Sbjct: 1661 CFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1718
Score = 48.5 bits (114), Expect = 5e-06
Identities = 23/60 (38%), Positives = 33/60 (55%), Gaps = 5/60 (8%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-----VDGEWSSALPVCKL 193
C PG P +G G++F+LGST+ + C++ Y L G + C V WS PVCK+
Sbjct: 446 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 505
Score = 46.2 bits (108), Expect = 3e-05
Identities = 22/54 (40%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE-WSSALPVC 191
C PG PVHG G++F++GST+S+ C+ Y L + C WS LP C
Sbjct: 970 CLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC 1023
Score = 45.1 bits (105), Expect = 6e-05
Identities = 22/56 (39%), Positives = 30/56 (53%), Gaps = 3/56 (5%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVC 191
C+ PG P +G G NF +G T+++ C Y L G E C+ G WS+ LP C
Sbjct: 1142 CEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1197
Score = 42.7 bits (99), Expect = 3e-04
Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 3/61 (4%)
Query: 137 RDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVCKL 193
+ C P +G+ GN+FT+G TIS+ C Y L+G C+ G W+ LP C+
Sbjct: 2182 QSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEA 2241
Query: 194 I 194
+
Sbjct: 2242 L 2242
Score = 42.0 bits (97), Expect = 5e-04
Identities = 16/58 (27%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
Query: 135 KSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVC 191
+ C PG P++G EG+ F+ + + C+ + L+G + C + +WS+ +P+C
Sbjct: 620 EKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC 677
Score = 41.2 bits (95), Expect = 9e-04
Identities = 22/59 (37%), Positives = 33/59 (55%), Gaps = 5/59 (8%)
Query: 138 DCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLV-GVQEQQCV--DGE--WSSALPVC 191
+C PG P++ G+NF LGS+IS CE+ + G + C+ DG+ WS +P C
Sbjct: 793 ECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC 851
Score = 38.9 bits (89), Expect = 0.004
Identities = 19/63 (30%), Positives = 26/63 (41%), Gaps = 5/63 (7%)
Query: 135 KSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV-----DGEWSSALP 189
+S C PG P G G F +G I Y C Y L G + C+ W +P
Sbjct: 134 QSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVP 193
Query: 190 VCK 192
+C+
Sbjct: 194 ICR 196
Score = 37.4 bits (85), Expect = 0.013
Identities = 22/57 (38%), Positives = 25/57 (43%), Gaps = 4/57 (7%)
Query: 139 CDPPGNPVHGY-FEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE---WSSALPVC 191
C+ PG P GY GSTI Y C Y L G +C+ GE W LP C
Sbjct: 1314 CEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC 1370
Score = 37.0 bits (84), Expect = 0.016
Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 4/57 (7%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE----WSSALPVC 191
C PG P++G G+ G T+ + C+ Y L G + C+ E W + PVC
Sbjct: 1488 CRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1544
Score = 36.6 bits (83), Expect = 0.021
Identities = 24/96 (25%), Positives = 38/96 (39%), Gaps = 3/96 (3%)
Query: 72 TTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED--HTWAP 129
T +E L C DP + + D +TF C+ Y L+G++ CL W+
Sbjct: 1133 TFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSA 1192
Query: 130 PFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 165
P P C + +C G N+ L ++ C
Sbjct: 1193 PLPRCVA-ECGASATNNEGILLSPNYPLNYENNHEC 1227
Score = 35.8 bits (81), Expect = 0.037
Identities = 18/63 (28%), Positives = 26/63 (41%), Gaps = 2/63 (3%)
Query: 74 TECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED--HTWAPPF 131
T L CP+P + V D ++F C+ Y L+G + C+ W P
Sbjct: 2005 TAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPI 2064
Query: 132 PIC 134
PIC
Sbjct: 2065 PIC 2067
Score = 35.0 bits (79), Expect = 0.062
Identities = 19/79 (24%), Positives = 30/79 (37%), Gaps = 4/79 (5%)
Query: 81 CPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLE----DHTWAPPFPICKS 136
CPDP ++ + F C++ Y+L+G+ C W+ P+CK
Sbjct: 446 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 505
Query: 137 RDCDPPGNPVHGYFEGNNF 155
+ C G F NF
Sbjct: 506 KTCGSNLQGPSGTFTSPNF 524
Score = 34.7 bits (78), Expect = 0.081
Identities = 19/65 (29%), Positives = 27/65 (41%), Gaps = 5/65 (7%)
Query: 132 PICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-----GEWSS 186
P S C P G GN F +GS++ + C Y L G +C +W+
Sbjct: 1831 PRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWND 1890
Query: 187 ALPVC 191
+LP C
Sbjct: 1891 SLPTC 1895
Score = 34.3 bits (77), Expect = 0.11
Identities = 19/62 (30%), Positives = 25/62 (40%), Gaps = 2/62 (3%)
Query: 77 RLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLE--DHTWAPPFPIC 134
+L CPDP F V I+F C Y L G++ CL W P P C
Sbjct: 2180 QLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRC 2239
Query: 135 KS 136
++
Sbjct: 2240 EA 2241
Score = 33.9 bits (76), Expect = 0.14
Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 3/64 (4%)
Query: 74 TECRLGHCPDPVLVNGEFSSSGPVNVSDK-ITFMCNDHYILKGSNRSQCL--EDHTWAPP 130
T L HC DP + + S + + I + CN Y L GS+ +C+ E W P
Sbjct: 1307 TSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYP 1366
Query: 131 FPIC 134
P C
Sbjct: 1367 LPSC 1370
Score = 33.5 bits (75), Expect = 0.18
Identities = 16/45 (35%), Positives = 24/45 (53%), Gaps = 4/45 (8%)
Query: 98 NVSDKITFMCNDHYILKGSNRSQCLEDH----TWAPPFPICKSRD 138
+V DKI + C YIL G + C+ + +W P PIC++ D
Sbjct: 155 DVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 199
Score = 33.5 bits (75), Expect = 0.18
Identities = 19/58 (32%), Positives = 28/58 (48%), Gaps = 5/58 (8%)
Query: 81 CPDP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLE---DHTWAPPFPIC 134
C DP V +NG + G D + F C+ Y L+G R C++ + W P P+C
Sbjct: 1488 CRDPGVPMNGTRNGDGR-EPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1544
Score = 33.5 bits (75), Expect = 0.18
Identities = 21/82 (25%), Positives = 34/82 (41%), Gaps = 4/82 (4%)
Query: 17 ASDAEHCPELPPVDNSIFVAKEVE-GQILGTYVCIKGYHLVGKKTLFC--NASKEWDNTT 73
A + CP+ P N + + GQ + ++ C GY L+G L C S+ W++
Sbjct: 2178 AYQLQSCPDPRPFRNGFVIGNDFTVGQTI-SFECFPGYTLIGNSALTCLHGVSRNWNHPL 2236
Query: 74 TECRLGHCPDPVLVNGEFSSSG 95
C + +NG S G
Sbjct: 2237 PRCEALCGGNITAMNGTIYSPG 2258
Score = 30.0 bits (66), Expect = 2.0
Identities = 10/37 (27%), Positives = 18/37 (48%)
Query: 98 NVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPIC 134
++ ++F C+ Y L C ++H W+ P P C
Sbjct: 987 SIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC 1023
Score = 29.6 bits (65), Expect = 2.6
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 5/64 (7%)
Query: 23 CPELPPVDNSIFVAKEVEGQI--LGTYVCIKGYHLVGKKTLFCNASK--EWDNTTTECRL 78
C PPV N+ + ++ E +I + Y C+ G+ LVG L C + + D C++
Sbjct: 2355 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2414
Query: 79 GHCP 82
CP
Sbjct: 2415 -LCP 2417
Score = 28.9 bits (63), Expect = 4.5
Identities = 22/111 (19%), Positives = 42/111 (37%), Gaps = 10/111 (9%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLG-----HCPDPVLVNGEFSSSGPVNVSD 101
+ C G+ L+G+K++ C + +W C P +++ ++ N++
Sbjct: 648 FECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNC 707
Query: 102 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEG 152
T + + GS D F +D D P +P+ G F G
Sbjct: 708 IWTIISD-----PGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTG 753
Score = 27.7 bits (60), Expect = 9.9
Identities = 20/63 (31%), Positives = 27/63 (42%), Gaps = 5/63 (7%)
Query: 137 RDCDPPGNPVHGYF--EGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE---WSSALPVC 191
R C PP + E + F +G I Y C + LVG C GE A PVC
Sbjct: 2353 RVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVC 2412
Query: 192 KLI 194
+++
Sbjct: 2413 QVL 2415
>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
sapiens]
Length = 3538
Score = 103 bits (257), Expect = 1e-22
Identities = 52/174 (29%), Positives = 80/174 (45%), Gaps = 3/174 (1%)
Query: 23 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 82
C ELP N + + + C G+ LVG C +S W + T C GHC
Sbjct: 2590 CGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCG 2649
Query: 83 DP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 141
P ++VNG+ D + + CN + L GS+ C +DH W+ P C C
Sbjct: 2650 IPELIVNGQVIGEN-YGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGH 2708
Query: 142 PGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 194
PG+P++G GN F +++ C Y + G + QC + +WS P+CK++
Sbjct: 2709 PGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVV 2762
Score = 95.9 bits (237), Expect = 3e-20
Identities = 54/173 (31%), Positives = 78/173 (45%), Gaps = 20/173 (11%)
Query: 39 VEGQILG---------TYVCIKGYHLVGKKTLFCNASKEWDNTTTEC---RLGHCPDPVL 86
V GQ++G Y C G+ L+G C W C GH P+
Sbjct: 2655 VNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIY 2714
Query: 87 VNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPV 146
G S +G N +D +TF CN Y+++G ++QC + W+ P P+CK +C PG P
Sbjct: 2715 --GRTSGNG-FNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPA 2771
Query: 147 H----GYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 194
+ E NFT G+ + Y C Y+L G C +G+W LP C +I
Sbjct: 2772 NSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMI 2824
Score = 91.7 bits (226), Expect = 6e-19
Identities = 48/165 (29%), Positives = 74/165 (44%), Gaps = 4/165 (2%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-VLVNGEFSSSGPVNVSDKITF 105
Y C GY L G + C A+ W EC+ C +P NG+ S + +
Sbjct: 2911 YACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIY 2970
Query: 106 MCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 165
C + YIL G + QC + TW+ P C C PG P +G G+++ +G +SY C
Sbjct: 2971 SCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMC 3030
Query: 166 EDRY--YLVGVQEQQC-VDGEWSSALPVCKLIQEAPKPECEKALL 207
+ Y L G + + C ++G WS +P C+ + P+ L
Sbjct: 3031 QPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRL 3075
Score = 86.7 bits (213), Expect = 2e-17
Identities = 46/151 (30%), Positives = 70/151 (46%), Gaps = 5/151 (3%)
Query: 46 TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-VLVNGEFSSS---GPVNVSD 101
T+ C GY + G C A+++W + C++ +C DP + N + S G
Sbjct: 2729 TFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGT 2788
Query: 102 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTI 161
+ + CN Y L GS+ C + W P P C DC PG P + G +T GST+
Sbjct: 2789 VVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTV 2848
Query: 162 SYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 191
Y C + L+G + C ++G WS + P C
Sbjct: 2849 HYSCTGKRSLLGQSSRTCQLNGHWSGSQPHC 2879
Score = 84.0 bits (206), Expect = 1e-16
Identities = 45/153 (29%), Positives = 65/153 (42%), Gaps = 4/153 (2%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFM 106
Y C GY L G L C + +WD EC + C P + S + +
Sbjct: 2792 YDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYS 2851
Query: 107 CNDHYILKGSNRSQCLEDHTWAPPFPICK---SRDCDPPGNPVHGYFEGNNFTLGSTISY 163
C L G + C + W+ P C + C PG P HG + +NF ST+ Y
Sbjct: 2852 CTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRY 2911
Query: 164 YCEDRYYLVGVQEQQCV-DGEWSSALPVCKLIQ 195
C+ Y L G +E+ C+ +G W+ P CK +Q
Sbjct: 2912 ACDTGYILHGSEERTCLANGSWTGRQPECKAVQ 2944
Score = 78.6 bits (192), Expect = 5e-15
Identities = 52/192 (27%), Positives = 78/192 (40%), Gaps = 15/192 (7%)
Query: 8 CLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASK 67
C+M+ D H P +PP N++ ++ Y C L+G+ + C +
Sbjct: 2821 CIMI-------DCGH-PGVPP--NAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNG 2870
Query: 68 EWDNTTTECR---LGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED 124
W + C G C DP + + C+ YIL GS CL +
Sbjct: 2871 HWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLAN 2930
Query: 125 HTWAPPFPICKSRDCDPPGNPVHG-YFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDG 182
+W P CK+ C PG +G F + T S++ Y C + Y L G +QC +G
Sbjct: 2931 GSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANG 2990
Query: 183 EWSSALPVCKLI 194
WS LP C +I
Sbjct: 2991 TWSGTLPNCTII 3002
Score = 78.6 bits (192), Expect = 5e-15
Identities = 49/175 (28%), Positives = 73/175 (41%), Gaps = 7/175 (4%)
Query: 23 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 82
CP P + N + +Y+C GY L L C + W +C C
Sbjct: 3064 CPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCG 3123
Query: 83 DP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPIC---KSRD 138
DP + G+ + S+ ++F CN +IL GS+ C D TW+ P C
Sbjct: 3124 DPGIPAQGKREGKSFIYQSE-VSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTS 3182
Query: 139 CDPPGNPVHGYFEGN-NFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVC 191
C+ PG P HG F +GS + ++C+ + L G + C+ D WS P C
Sbjct: 3183 CENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPEC 3237
Score = 76.6 bits (187), Expect = 2e-14
Identities = 48/172 (27%), Positives = 72/172 (41%), Gaps = 6/172 (3%)
Query: 46 TYVCIKGY--HLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKI 103
+Y+C GY L G + C + W CR CP P ++ + I
Sbjct: 3027 SYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSI 3086
Query: 104 TFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISY 163
+++C+ Y L C+ + TW+ P C + C PG P G EG +F S +S+
Sbjct: 3087 SYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSF 3146
Query: 164 YCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAPKPECEKALLAFQESKN 214
C + LVG + C DG WS + P C E + CE + S+N
Sbjct: 3147 SCNFPFILVGSSTRICQADGTWSGSSPHC---IEPTQTSCENPGVPRHGSQN 3195
Score = 73.2 bits (178), Expect = 2e-13
Identities = 45/166 (27%), Positives = 74/166 (44%), Gaps = 11/166 (6%)
Query: 46 TYVCIKGYHLVGKKTLFCNASKEWDNTTTEC---RLGHCPDP-VLVNGEFSSSGPVNVSD 101
++ C + LVG T C A W ++ C C +P V +G +++ V
Sbjct: 3145 SFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGS 3204
Query: 102 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNF-TLGST 160
+ F C ++L+GS CL D TW+ P C C P P H G + + G T
Sbjct: 3205 VVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYT 3264
Query: 161 ISYYCEDRYYLVGVQEQQCV--DGEWSSALPVC----KLIQEAPKP 200
+ Y C+ ++L G E + D W+ +P+C K++ + P+P
Sbjct: 3265 LIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRP 3310
Score = 63.9 bits (154), Expect = 1e-10
Identities = 49/179 (27%), Positives = 73/179 (40%), Gaps = 14/179 (7%)
Query: 24 PELPPVDNSIFVAKEVEGQILGT--YVCIKGYHLVGKKTLFCNASK----EWDNTTTECR 77
PE PP ++ + GQ+ + C +G+ LVGK + C S WD C+
Sbjct: 2468 PESPPHG---YIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2524
Query: 78 LGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYIL--KGSNRSQCLEDHTWAP--PFPI 133
C P + V ++T+ CND Y L K + C D TW+ P
Sbjct: 2525 AISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPR 2584
Query: 134 CKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVC 191
C C P +G G + GST + C+ + LVG ++C+ G WS + C
Sbjct: 2585 CVVISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC 2643
Score = 50.4 bits (119), Expect = 1e-06
Identities = 30/109 (27%), Positives = 50/109 (45%), Gaps = 11/109 (10%)
Query: 103 ITFMCNDHYILKGSNRSQCLED----HTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLG 158
+ + C+ + L G + + C + H W P P C++ C P P +G ++ +G
Sbjct: 2488 VRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYLVG 2547
Query: 159 STISYYCEDRYYLVGVQEQQCV---DGEWS--SALPVCKLIQ--EAPKP 200
+ ++Y+C D Y L + V DG WS + P C +I E P P
Sbjct: 2548 TRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGELPTP 2596
Score = 48.9 bits (115), Expect = 4e-06
Identities = 23/58 (39%), Positives = 33/58 (56%), Gaps = 5/58 (8%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE-----WSSALPVC 191
C PGN ++G G ++ LGST++YYC+ Y L G C+ G+ W+ ALP C
Sbjct: 1597 CFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1654
Score = 48.5 bits (114), Expect = 5e-06
Identities = 23/60 (38%), Positives = 33/60 (55%), Gaps = 5/60 (8%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-----VDGEWSSALPVCKL 193
C PG P +G G++F+LGST+ + C++ Y L G + C V WS PVCK+
Sbjct: 382 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 441
Score = 46.2 bits (108), Expect = 3e-05
Identities = 22/54 (40%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE-WSSALPVC 191
C PG PVHG G++F++GST+S+ C+ Y L + C WS LP C
Sbjct: 906 CLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC 959
Score = 45.1 bits (105), Expect = 6e-05
Identities = 22/56 (39%), Positives = 30/56 (53%), Gaps = 3/56 (5%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVC 191
C+ PG P +G G NF +G T+++ C Y L G E C+ G WS+ LP C
Sbjct: 1078 CEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1133
Score = 42.7 bits (99), Expect = 3e-04
Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 3/61 (4%)
Query: 137 RDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVCKL 193
+ C P +G+ GN+FT+G TIS+ C Y L+G C+ G W+ LP C+
Sbjct: 2118 QSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEA 2177
Query: 194 I 194
+
Sbjct: 2178 L 2178
Score = 42.0 bits (97), Expect = 5e-04
Identities = 16/58 (27%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
Query: 135 KSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVC 191
+ C PG P++G EG+ F+ + + C+ + L+G + C + +WS+ +P+C
Sbjct: 556 EKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC 613
Score = 41.2 bits (95), Expect = 9e-04
Identities = 22/59 (37%), Positives = 33/59 (55%), Gaps = 5/59 (8%)
Query: 138 DCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLV-GVQEQQCV--DGE--WSSALPVC 191
+C PG P++ G+NF LGS+IS CE+ + G + C+ DG+ WS +P C
Sbjct: 729 ECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC 787
Score = 38.9 bits (89), Expect = 0.004
Identities = 19/63 (30%), Positives = 26/63 (41%), Gaps = 5/63 (7%)
Query: 135 KSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV-----DGEWSSALP 189
+S C PG P G G F +G I Y C Y L G + C+ W +P
Sbjct: 174 QSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVP 233
Query: 190 VCK 192
+C+
Sbjct: 234 ICR 236
Score = 37.4 bits (85), Expect = 0.013
Identities = 22/57 (38%), Positives = 25/57 (43%), Gaps = 4/57 (7%)
Query: 139 CDPPGNPVHGY-FEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE---WSSALPVC 191
C+ PG P GY GSTI Y C Y L G +C+ GE W LP C
Sbjct: 1250 CEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC 1306
Score = 37.0 bits (84), Expect = 0.016
Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 4/57 (7%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE----WSSALPVC 191
C PG P++G G+ G T+ + C+ Y L G + C+ E W + PVC
Sbjct: 1424 CRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1480
Score = 36.6 bits (83), Expect = 0.021
Identities = 24/96 (25%), Positives = 38/96 (39%), Gaps = 3/96 (3%)
Query: 72 TTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED--HTWAP 129
T +E L C DP + + D +TF C+ Y L+G++ CL W+
Sbjct: 1069 TFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSA 1128
Query: 130 PFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 165
P P C + +C G N+ L ++ C
Sbjct: 1129 PLPRCVA-ECGASATNNEGILLSPNYPLNYENNHEC 1163
Score = 35.8 bits (81), Expect = 0.037
Identities = 18/63 (28%), Positives = 26/63 (41%), Gaps = 2/63 (3%)
Query: 74 TECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED--HTWAPPF 131
T L CP+P + V D ++F C+ Y L+G + C+ W P
Sbjct: 1941 TAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPI 2000
Query: 132 PIC 134
PIC
Sbjct: 2001 PIC 2003
Score = 35.0 bits (79), Expect = 0.062
Identities = 19/79 (24%), Positives = 30/79 (37%), Gaps = 4/79 (5%)
Query: 81 CPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLE----DHTWAPPFPICKS 136
CPDP ++ + F C++ Y+L+G+ C W+ P+CK
Sbjct: 382 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 441
Query: 137 RDCDPPGNPVHGYFEGNNF 155
+ C G F NF
Sbjct: 442 KTCGSNLQGPSGTFTSPNF 460
Score = 34.7 bits (78), Expect = 0.081
Identities = 19/65 (29%), Positives = 27/65 (41%), Gaps = 5/65 (7%)
Query: 132 PICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-----GEWSS 186
P S C P G GN F +GS++ + C Y L G +C +W+
Sbjct: 1767 PRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWND 1826
Query: 187 ALPVC 191
+LP C
Sbjct: 1827 SLPTC 1831
Score = 34.3 bits (77), Expect = 0.11
Identities = 19/62 (30%), Positives = 25/62 (40%), Gaps = 2/62 (3%)
Query: 77 RLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLE--DHTWAPPFPIC 134
+L CPDP F V I+F C Y L G++ CL W P P C
Sbjct: 2116 QLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRC 2175
Query: 135 KS 136
++
Sbjct: 2176 EA 2177
Score = 33.9 bits (76), Expect = 0.14
Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 3/64 (4%)
Query: 74 TECRLGHCPDPVLVNGEFSSSGPVNVSDK-ITFMCNDHYILKGSNRSQCL--EDHTWAPP 130
T L HC DP + + S + + I + CN Y L GS+ +C+ E W P
Sbjct: 1243 TSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYP 1302
Query: 131 FPIC 134
P C
Sbjct: 1303 LPSC 1306
Score = 33.5 bits (75), Expect = 0.18
Identities = 16/45 (35%), Positives = 24/45 (53%), Gaps = 4/45 (8%)
Query: 98 NVSDKITFMCNDHYILKGSNRSQCLEDH----TWAPPFPICKSRD 138
+V DKI + C YIL G + C+ + +W P PIC++ D
Sbjct: 195 DVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 239
Score = 33.5 bits (75), Expect = 0.18
Identities = 19/58 (32%), Positives = 28/58 (48%), Gaps = 5/58 (8%)
Query: 81 CPDP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLE---DHTWAPPFPIC 134
C DP V +NG + G D + F C+ Y L+G R C++ + W P P+C
Sbjct: 1424 CRDPGVPMNGTRNGDGR-EPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1480
Score = 33.5 bits (75), Expect = 0.18
Identities = 21/82 (25%), Positives = 34/82 (41%), Gaps = 4/82 (4%)
Query: 17 ASDAEHCPELPPVDNSIFVAKEVE-GQILGTYVCIKGYHLVGKKTLFC--NASKEWDNTT 73
A + CP+ P N + + GQ + ++ C GY L+G L C S+ W++
Sbjct: 2114 AYQLQSCPDPRPFRNGFVIGNDFTVGQTI-SFECFPGYTLIGNSALTCLHGVSRNWNHPL 2172
Query: 74 TECRLGHCPDPVLVNGEFSSSG 95
C + +NG S G
Sbjct: 2173 PRCEALCGGNITAMNGTIYSPG 2194
Score = 30.0 bits (66), Expect = 2.0
Identities = 10/37 (27%), Positives = 18/37 (48%)
Query: 98 NVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPIC 134
++ ++F C+ Y L C ++H W+ P P C
Sbjct: 923 SIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC 959
Score = 29.6 bits (65), Expect = 2.6
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 5/64 (7%)
Query: 23 CPELPPVDNSIFVAKEVEGQI--LGTYVCIKGYHLVGKKTLFCNASK--EWDNTTTECRL 78
C PPV N+ + ++ E +I + Y C+ G+ LVG L C + + D C++
Sbjct: 2291 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2350
Query: 79 GHCP 82
CP
Sbjct: 2351 -LCP 2353
Score = 28.9 bits (63), Expect = 4.5
Identities = 22/111 (19%), Positives = 42/111 (37%), Gaps = 10/111 (9%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLG-----HCPDPVLVNGEFSSSGPVNVSD 101
+ C G+ L+G+K++ C + +W C P +++ ++ N++
Sbjct: 584 FECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNC 643
Query: 102 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEG 152
T + + GS D F +D D P +P+ G F G
Sbjct: 644 IWTIISD-----PGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTG 689
Score = 27.7 bits (60), Expect = 9.9
Identities = 20/63 (31%), Positives = 27/63 (42%), Gaps = 5/63 (7%)
Query: 137 RDCDPPGNPVHGYF--EGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE---WSSALPVC 191
R C PP + E + F +G I Y C + LVG C GE A PVC
Sbjct: 2289 RVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVC 2348
Query: 192 KLI 194
+++
Sbjct: 2349 QVL 2351
>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sapiens]
Length = 3707
Score = 103 bits (257), Expect = 1e-22
Identities = 52/174 (29%), Positives = 80/174 (45%), Gaps = 3/174 (1%)
Query: 23 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 82
C ELP N + + + C G+ LVG C +S W + T C GHC
Sbjct: 2759 CGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCG 2818
Query: 83 DP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 141
P ++VNG+ D + + CN + L GS+ C +DH W+ P C C
Sbjct: 2819 IPELIVNGQVIGEN-YGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGH 2877
Query: 142 PGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 194
PG+P++G GN F +++ C Y + G + QC + +WS P+CK++
Sbjct: 2878 PGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVV 2931
Score = 95.9 bits (237), Expect = 3e-20
Identities = 54/173 (31%), Positives = 78/173 (45%), Gaps = 20/173 (11%)
Query: 39 VEGQILG---------TYVCIKGYHLVGKKTLFCNASKEWDNTTTEC---RLGHCPDPVL 86
V GQ++G Y C G+ L+G C W C GH P+
Sbjct: 2824 VNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIY 2883
Query: 87 VNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPV 146
G S +G N +D +TF CN Y+++G ++QC + W+ P P+CK +C PG P
Sbjct: 2884 --GRTSGNG-FNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPA 2940
Query: 147 H----GYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 194
+ E NFT G+ + Y C Y+L G C +G+W LP C +I
Sbjct: 2941 NSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMI 2993
Score = 91.7 bits (226), Expect = 6e-19
Identities = 48/165 (29%), Positives = 74/165 (44%), Gaps = 4/165 (2%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-VLVNGEFSSSGPVNVSDKITF 105
Y C GY L G + C A+ W EC+ C +P NG+ S + +
Sbjct: 3080 YACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIY 3139
Query: 106 MCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 165
C + YIL G + QC + TW+ P C C PG P +G G+++ +G +SY C
Sbjct: 3140 SCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMC 3199
Query: 166 EDRY--YLVGVQEQQC-VDGEWSSALPVCKLIQEAPKPECEKALL 207
+ Y L G + + C ++G WS +P C+ + P+ L
Sbjct: 3200 QPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRL 3244
Score = 86.7 bits (213), Expect = 2e-17
Identities = 46/151 (30%), Positives = 70/151 (46%), Gaps = 5/151 (3%)
Query: 46 TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-VLVNGEFSSS---GPVNVSD 101
T+ C GY + G C A+++W + C++ +C DP + N + S G
Sbjct: 2898 TFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGT 2957
Query: 102 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTI 161
+ + CN Y L GS+ C + W P P C DC PG P + G +T GST+
Sbjct: 2958 VVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTV 3017
Query: 162 SYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 191
Y C + L+G + C ++G WS + P C
Sbjct: 3018 HYSCTGKRSLLGQSSRTCQLNGHWSGSQPHC 3048
Score = 84.0 bits (206), Expect = 1e-16
Identities = 45/153 (29%), Positives = 65/153 (42%), Gaps = 4/153 (2%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFM 106
Y C GY L G L C + +WD EC + C P + S + +
Sbjct: 2961 YDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYS 3020
Query: 107 CNDHYILKGSNRSQCLEDHTWAPPFPICK---SRDCDPPGNPVHGYFEGNNFTLGSTISY 163
C L G + C + W+ P C + C PG P HG + +NF ST+ Y
Sbjct: 3021 CTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRY 3080
Query: 164 YCEDRYYLVGVQEQQCV-DGEWSSALPVCKLIQ 195
C+ Y L G +E+ C+ +G W+ P CK +Q
Sbjct: 3081 ACDTGYILHGSEERTCLANGSWTGRQPECKAVQ 3113
Score = 78.6 bits (192), Expect = 5e-15
Identities = 52/192 (27%), Positives = 78/192 (40%), Gaps = 15/192 (7%)
Query: 8 CLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASK 67
C+M+ D H P +PP N++ ++ Y C L+G+ + C +
Sbjct: 2990 CIMI-------DCGH-PGVPP--NAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNG 3039
Query: 68 EWDNTTTECR---LGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED 124
W + C G C DP + + C+ YIL GS CL +
Sbjct: 3040 HWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLAN 3099
Query: 125 HTWAPPFPICKSRDCDPPGNPVHG-YFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDG 182
+W P CK+ C PG +G F + T S++ Y C + Y L G +QC +G
Sbjct: 3100 GSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANG 3159
Query: 183 EWSSALPVCKLI 194
WS LP C +I
Sbjct: 3160 TWSGTLPNCTII 3171
Score = 78.6 bits (192), Expect = 5e-15
Identities = 49/175 (28%), Positives = 73/175 (41%), Gaps = 7/175 (4%)
Query: 23 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 82
CP P + N + +Y+C GY L L C + W +C C
Sbjct: 3233 CPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCG 3292
Query: 83 DP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPIC---KSRD 138
DP + G+ + S+ ++F CN +IL GS+ C D TW+ P C
Sbjct: 3293 DPGIPAQGKREGKSFIYQSE-VSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTS 3351
Query: 139 CDPPGNPVHGYFEGN-NFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVC 191
C+ PG P HG F +GS + ++C+ + L G + C+ D WS P C
Sbjct: 3352 CENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPEC 3406
Score = 76.6 bits (187), Expect = 2e-14
Identities = 48/172 (27%), Positives = 72/172 (41%), Gaps = 6/172 (3%)
Query: 46 TYVCIKGY--HLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKI 103
+Y+C GY L G + C + W CR CP P ++ + I
Sbjct: 3196 SYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSI 3255
Query: 104 TFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISY 163
+++C+ Y L C+ + TW+ P C + C PG P G EG +F S +S+
Sbjct: 3256 SYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSF 3315
Query: 164 YCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAPKPECEKALLAFQESKN 214
C + LVG + C DG WS + P C E + CE + S+N
Sbjct: 3316 SCNFPFILVGSSTRICQADGTWSGSSPHC---IEPTQTSCENPGVPRHGSQN 3364
Score = 73.2 bits (178), Expect = 2e-13
Identities = 45/166 (27%), Positives = 74/166 (44%), Gaps = 11/166 (6%)
Query: 46 TYVCIKGYHLVGKKTLFCNASKEWDNTTTEC---RLGHCPDP-VLVNGEFSSSGPVNVSD 101
++ C + LVG T C A W ++ C C +P V +G +++ V
Sbjct: 3314 SFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGS 3373
Query: 102 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNF-TLGST 160
+ F C ++L+GS CL D TW+ P C C P P H G + + G T
Sbjct: 3374 VVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYT 3433
Query: 161 ISYYCEDRYYLVGVQEQQCV--DGEWSSALPVC----KLIQEAPKP 200
+ Y C+ ++L G E + D W+ +P+C K++ + P+P
Sbjct: 3434 LIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRP 3479
Score = 57.8 bits (138), Expect = 9e-09
Identities = 44/158 (27%), Positives = 66/158 (41%), Gaps = 12/158 (7%)
Query: 46 TYVCIKGYHLVGKK--TLFCNASKEWDN--TTTECRLGHCPDP---VLVNGEFS--SSGP 96
TY C GY L K+ T C + W N T C + CP +L +G + +
Sbjct: 2655 TYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSH 2714
Query: 97 VNVSDKITFMCNDHYILKGSNRSQCLEDHTWA--PPFPICKSRDCDPPGNPVHGYFEGNN 154
K+ F C+ Y G +CL + TW+ P C+ C P +G G
Sbjct: 2715 YEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQ 2774
Query: 155 FTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVC 191
+ GST + C+ + LVG ++C+ G WS + C
Sbjct: 2775 TSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC 2812
Score = 57.4 bits (137), Expect = 1e-08
Identities = 50/197 (25%), Positives = 83/197 (42%), Gaps = 23/197 (11%)
Query: 24 PELPPVDNSIFVAKEVEGQILGT--YVCIKGYHLVGKKTLFCNASK----EWDNTTTECR 77
PE PP ++ + GQ+ + C +G+ LVGK + C S WD C+
Sbjct: 2572 PESPPHG---YIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2628
Query: 78 LGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYIL--KGSNRSQCLEDHTWA--PPFPI 133
C P + V ++T+ CND Y L K + C D TW+ P
Sbjct: 2629 AISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPR 2688
Query: 134 CKSRDCDPPGNPV--HGYF---EGNNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWS-- 185
C C + + HG + G+++ + + + C+ Y+ +G +C+ +G WS
Sbjct: 2689 CVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWR 2748
Query: 186 SALPVCKLIQ--EAPKP 200
+ P C++I E P P
Sbjct: 2749 NERPYCQIISCGELPTP 2765
Score = 48.9 bits (115), Expect = 4e-06
Identities = 23/58 (39%), Positives = 33/58 (56%), Gaps = 5/58 (8%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE-----WSSALPVC 191
C PGN ++G G ++ LGST++YYC+ Y L G C+ G+ W+ ALP C
Sbjct: 1701 CFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1758
Score = 48.5 bits (114), Expect = 5e-06
Identities = 23/60 (38%), Positives = 33/60 (55%), Gaps = 5/60 (8%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-----VDGEWSSALPVCKL 193
C PG P +G G++F+LGST+ + C++ Y L G + C V WS PVCK+
Sbjct: 486 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 545
Score = 46.2 bits (108), Expect = 3e-05
Identities = 22/54 (40%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE-WSSALPVC 191
C PG PVHG G++F++GST+S+ C+ Y L + C WS LP C
Sbjct: 1010 CLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC 1063
Score = 45.1 bits (105), Expect = 6e-05
Identities = 22/56 (39%), Positives = 30/56 (53%), Gaps = 3/56 (5%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVC 191
C+ PG P +G G NF +G T+++ C Y L G E C+ G WS+ LP C
Sbjct: 1182 CEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1237
Score = 42.7 bits (99), Expect = 3e-04
Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 3/61 (4%)
Query: 137 RDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVCKL 193
+ C P +G+ GN+FT+G TIS+ C Y L+G C+ G W+ LP C+
Sbjct: 2222 QSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEA 2281
Query: 194 I 194
+
Sbjct: 2282 L 2282
Score = 42.0 bits (97), Expect = 5e-04
Identities = 16/58 (27%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
Query: 135 KSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVC 191
+ C PG P++G EG+ F+ + + C+ + L+G + C + +WS+ +P+C
Sbjct: 660 EKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPIC 717
Score = 41.2 bits (95), Expect = 9e-04
Identities = 22/59 (37%), Positives = 33/59 (55%), Gaps = 5/59 (8%)
Query: 138 DCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLV-GVQEQQCV--DGE--WSSALPVC 191
+C PG P++ G+NF LGS+IS CE+ + G + C+ DG+ WS +P C
Sbjct: 833 ECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC 891
Score = 38.9 bits (89), Expect = 0.004
Identities = 19/63 (30%), Positives = 26/63 (41%), Gaps = 5/63 (7%)
Query: 135 KSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV-----DGEWSSALP 189
+S C PG P G G F +G I Y C Y L G + C+ W +P
Sbjct: 174 QSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVP 233
Query: 190 VCK 192
+C+
Sbjct: 234 ICR 236
Score = 37.4 bits (85), Expect = 0.013
Identities = 22/57 (38%), Positives = 25/57 (43%), Gaps = 4/57 (7%)
Query: 139 CDPPGNPVHGY-FEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE---WSSALPVC 191
C+ PG P GY GSTI Y C Y L G +C+ GE W LP C
Sbjct: 1354 CEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC 1410
Score = 37.0 bits (84), Expect = 0.016
Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 4/57 (7%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE----WSSALPVC 191
C PG P++G G+ G T+ + C+ Y L G + C+ E W + PVC
Sbjct: 1528 CRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1584
Score = 36.6 bits (83), Expect = 0.021
Identities = 24/96 (25%), Positives = 38/96 (39%), Gaps = 3/96 (3%)
Query: 72 TTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED--HTWAP 129
T +E L C DP + + D +TF C+ Y L+G++ CL W+
Sbjct: 1173 TFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSA 1232
Query: 130 PFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 165
P P C + +C G N+ L ++ C
Sbjct: 1233 PLPRCVA-ECGASATNNEGILLSPNYPLNYENNHEC 1267
Score = 35.8 bits (81), Expect = 0.037
Identities = 18/63 (28%), Positives = 26/63 (41%), Gaps = 2/63 (3%)
Query: 74 TECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED--HTWAPPF 131
T L CP+P + V D ++F C+ Y L+G + C+ W P
Sbjct: 2045 TAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPI 2104
Query: 132 PIC 134
PIC
Sbjct: 2105 PIC 2107
Score = 35.0 bits (79), Expect = 0.062
Identities = 19/79 (24%), Positives = 30/79 (37%), Gaps = 4/79 (5%)
Query: 81 CPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLE----DHTWAPPFPICKS 136
CPDP ++ + F C++ Y+L+G+ C W+ P+CK
Sbjct: 486 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 545
Query: 137 RDCDPPGNPVHGYFEGNNF 155
+ C G F NF
Sbjct: 546 KTCGSNLQGPSGTFTSPNF 564
Score = 34.7 bits (78), Expect = 0.081
Identities = 19/65 (29%), Positives = 27/65 (41%), Gaps = 5/65 (7%)
Query: 132 PICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-----GEWSS 186
P S C P G GN F +GS++ + C Y L G +C +W+
Sbjct: 1871 PRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWND 1930
Query: 187 ALPVC 191
+LP C
Sbjct: 1931 SLPTC 1935
Score = 34.3 bits (77), Expect = 0.11
Identities = 19/62 (30%), Positives = 25/62 (40%), Gaps = 2/62 (3%)
Query: 77 RLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLE--DHTWAPPFPIC 134
+L CPDP F V I+F C Y L G++ CL W P P C
Sbjct: 2220 QLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRC 2279
Query: 135 KS 136
++
Sbjct: 2280 EA 2281
Score = 33.9 bits (76), Expect = 0.14
Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 3/64 (4%)
Query: 74 TECRLGHCPDPVLVNGEFSSSGPVNVSDK-ITFMCNDHYILKGSNRSQCL--EDHTWAPP 130
T L HC DP + + S + + I + CN Y L GS+ +C+ E W P
Sbjct: 1347 TSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYP 1406
Query: 131 FPIC 134
P C
Sbjct: 1407 LPSC 1410
Score = 33.5 bits (75), Expect = 0.18
Identities = 16/45 (35%), Positives = 24/45 (53%), Gaps = 4/45 (8%)
Query: 98 NVSDKITFMCNDHYILKGSNRSQCLEDH----TWAPPFPICKSRD 138
+V DKI + C YIL G + C+ + +W P PIC++ D
Sbjct: 195 DVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 239
Score = 33.5 bits (75), Expect = 0.18
Identities = 19/58 (32%), Positives = 28/58 (48%), Gaps = 5/58 (8%)
Query: 81 CPDP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLE---DHTWAPPFPIC 134
C DP V +NG + G D + F C+ Y L+G R C++ + W P P+C
Sbjct: 1528 CRDPGVPMNGTRNGDGR-EPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1584
Score = 33.5 bits (75), Expect = 0.18
Identities = 21/82 (25%), Positives = 34/82 (41%), Gaps = 4/82 (4%)
Query: 17 ASDAEHCPELPPVDNSIFVAKEVE-GQILGTYVCIKGYHLVGKKTLFC--NASKEWDNTT 73
A + CP+ P N + + GQ + ++ C GY L+G L C S+ W++
Sbjct: 2218 AYQLQSCPDPRPFRNGFVIGNDFTVGQTI-SFECFPGYTLIGNSALTCLHGVSRNWNHPL 2276
Query: 74 TECRLGHCPDPVLVNGEFSSSG 95
C + +NG S G
Sbjct: 2277 PRCEALCGGNITAMNGTIYSPG 2298
Score = 30.0 bits (66), Expect = 2.0
Identities = 10/37 (27%), Positives = 18/37 (48%)
Query: 98 NVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPIC 134
++ ++F C+ Y L C ++H W+ P P C
Sbjct: 1027 SIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC 1063
Score = 29.6 bits (65), Expect = 2.6
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 5/64 (7%)
Query: 23 CPELPPVDNSIFVAKEVEGQI--LGTYVCIKGYHLVGKKTLFCNASK--EWDNTTTECRL 78
C PPV N+ + ++ E +I + Y C+ G+ LVG L C + + D C++
Sbjct: 2395 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2454
Query: 79 GHCP 82
CP
Sbjct: 2455 -LCP 2457
Score = 28.9 bits (63), Expect = 4.5
Identities = 22/111 (19%), Positives = 42/111 (37%), Gaps = 10/111 (9%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLG-----HCPDPVLVNGEFSSSGPVNVSD 101
+ C G+ L+G+K++ C + +W C P +++ ++ N++
Sbjct: 688 FECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNC 747
Query: 102 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEG 152
T + + GS D F +D D P +P+ G F G
Sbjct: 748 IWTIISD-----PGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTG 793
Score = 27.7 bits (60), Expect = 9.9
Identities = 20/63 (31%), Positives = 27/63 (42%), Gaps = 5/63 (7%)
Query: 137 RDCDPPGNPVHGYF--EGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE---WSSALPVC 191
R C PP + E + F +G I Y C + LVG C GE A PVC
Sbjct: 2393 RVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVC 2452
Query: 192 KLI 194
+++
Sbjct: 2453 QVL 2455
>gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens]
Length = 3487
Score = 99.8 bits (247), Expect = 2e-21
Identities = 53/172 (30%), Positives = 80/172 (46%), Gaps = 5/172 (2%)
Query: 23 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHC- 81
C ELP N + + C GY LVG + C A+ W + C GHC
Sbjct: 2658 CGELPIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCG 2717
Query: 82 -PDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCD 140
P+P+ VNG + + + + CN + L G + C +DH W+ P C C
Sbjct: 2718 TPEPI-VNGHINGEN-YSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCG 2775
Query: 141 PPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 191
PG+P H G+++T+G+ + Y C + LVG + C +DG W+ +LP C
Sbjct: 2776 HPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHC 2827
Score = 78.2 bits (191), Expect = 6e-15
Identities = 41/148 (27%), Positives = 68/148 (45%), Gaps = 3/148 (2%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFM 106
Y C +GY+ G + C+ + W + EC + +C DP + + +T+
Sbjct: 2918 YECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPGIPANGLRLGNDFRYNKTVTYQ 2977
Query: 107 CNDHYILKGSNRS--QCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYY 164
C Y+++ S C +D TW P+CK+ C PP +G G++F GS+++Y
Sbjct: 2978 CVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGSDFMWGSSVTYA 3037
Query: 165 CEDRYYLVGVQEQQCV-DGEWSSALPVC 191
C + Y L C +G W+ LP C
Sbjct: 3038 CLEGYQLSLPAVFTCEGNGSWTGELPQC 3065
Score = 77.0 bits (188), Expect = 1e-14
Identities = 48/179 (26%), Positives = 67/179 (37%), Gaps = 4/179 (2%)
Query: 20 AEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLG 79
A HC P+ N + + Y C G+ L+G C W T C L
Sbjct: 2713 AGHCGTPEPIVNGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLV 2772
Query: 80 HCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRD- 138
C P S V + + C L G++ C D W P C
Sbjct: 2773 SCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSV 2832
Query: 139 --CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 194
C PG P HG G++F G+ + + CE + L G E+ C +G WS + P C +I
Sbjct: 2833 GVCGDPGIPAHGIRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVI 2891
Score = 74.7 bits (182), Expect = 7e-14
Identities = 45/162 (27%), Positives = 70/162 (43%), Gaps = 7/162 (4%)
Query: 46 TYVCIKGYHLVGKKTLFCNASKEWDNTTTEC---RLGHCPDPVLVN-GEFSSSGPVNVSD 101
++ C LVG FC + W T C L C DP + G ++S V
Sbjct: 3093 SFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFGIQNNSQGYQVGS 3152
Query: 102 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNF-TLGST 160
+ F C Y+L+GS CL + TW+ P C C P P H + ++G T
Sbjct: 3153 TVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCRQPETPTHANVGALDLPSMGYT 3212
Query: 161 ISYYCEDRYYLVGVQEQQC--VDGEWSSALPVCKLIQEAPKP 200
+ Y C++ + L G E + DG W+ P+C ++ + +P
Sbjct: 3213 LIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEVRPSGRP 3254
Score = 73.6 bits (179), Expect = 2e-13
Identities = 45/158 (28%), Positives = 63/158 (39%), Gaps = 4/158 (2%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-VLVNGEFSSSGPVNVSDKITF 105
+ C G+ L G C A+ W + EC + C +P N S + S I +
Sbjct: 2859 FSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSSIVY 2918
Query: 106 MCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 165
C + Y G C + TW P C +C PG P +G GN+F T++Y C
Sbjct: 2919 ECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPGIPANGLRLGNDFRYNKTVTYQC 2978
Query: 166 EDRYYLVG--VQEQQCV-DGEWSSALPVCKLIQEAPKP 200
Y + V C D W+ PVCK + P P
Sbjct: 2979 VPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPP 3016
Score = 70.1 bits (170), Expect = 2e-12
Identities = 45/150 (30%), Positives = 65/150 (43%), Gaps = 5/150 (3%)
Query: 46 TYVCIKGYHLVGKKT--LFCNASKEWDNTTTECRLGHC-PDPVLVNGEFSSSGPVNVSDK 102
TY C+ GY + + L C + W+ T C+ C P P++ NG+ S + S
Sbjct: 2975 TYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGSDFMWGSS- 3033
Query: 103 ITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTIS 162
+T+ C + Y L C + +W P C C PG P G E F+ S++S
Sbjct: 3034 VTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGDPGVPSRGRREDRGFSYRSSVS 3093
Query: 163 YYCEDRYYLVGVQEQQC-VDGEWSSALPVC 191
+ C LVG + C DG WS P C
Sbjct: 3094 FSCHPPLVLVGSPRRFCQSDGTWSGTQPSC 3123
Score = 70.1 bits (170), Expect = 2e-12
Identities = 45/174 (25%), Positives = 67/174 (38%), Gaps = 5/174 (2%)
Query: 23 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 82
C P + N V + TY C++GY L C + W +C C
Sbjct: 3012 CKPPPLIPNGKVVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCG 3071
Query: 83 DPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPIC---KSRDC 139
DP + + + ++F C+ +L GS R C D TW+ P C C
Sbjct: 3072 DPGVPSRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTC 3131
Query: 140 DPPGNPVHGYFEGN-NFTLGSTISYYCEDRYYLVGVQEQQCVDG-EWSSALPVC 191
PG P G + + +GST+ + C+ Y L G + C+ WS P C
Sbjct: 3132 ADPGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDC 3185
Score = 52.4 bits (124), Expect = 4e-07
Identities = 34/118 (28%), Positives = 52/118 (44%), Gaps = 11/118 (9%)
Query: 76 CRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED----HTWAPPF 131
C L P + G+ S+ I F CN Y L G + + C H W+
Sbjct: 2468 CSLPRAPLHGFILGQTSTQP----GGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAI 2523
Query: 132 PICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQE--QQCVD-GEWSS 186
P+C++ C P P +G G +T+G+ Y C + Y+L E +C+D G WS+
Sbjct: 2524 PLCQALSCGLPEAPKNGMVFGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSN 2581
Score = 51.2 bits (121), Expect = 8e-07
Identities = 44/180 (24%), Positives = 69/180 (38%), Gaps = 14/180 (7%)
Query: 24 PELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVG--KKTLFCNASKEWDNTTT--ECRLG 79
PE P N + KE Y C +GYHL + T C + W N +C
Sbjct: 2534 PEAPK--NGMVFGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPV 2591
Query: 80 HCPDPVLVNGEFSS-----SGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWA--PPFP 132
CPD ++ E ++ +C+ Y G +C + W+ P
Sbjct: 2592 TCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTP 2651
Query: 133 ICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVC 191
C+ C P +G+ G G+T + C Y LVG + ++C+ +G WS + C
Sbjct: 2652 TCRIISCGELPIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRC 2711
Score = 45.4 bits (106), Expect = 5e-05
Identities = 21/61 (34%), Positives = 35/61 (57%), Gaps = 1/61 (1%)
Query: 135 KSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG-EWSSALPVCKL 193
+S C PG PV+G GN+F +G+ +++ C+ Y L + +C +WS ALP C+
Sbjct: 863 QSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEA 922
Query: 194 I 194
+
Sbjct: 923 L 923
Score = 43.9 bits (102), Expect = 1e-04
Identities = 25/93 (26%), Positives = 39/93 (41%), Gaps = 6/93 (6%)
Query: 79 GH--CPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDH----TWAPPFP 132
GH CPDP + + + F CN+ Y L+GS R C++ W+ P
Sbjct: 339 GHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRP 398
Query: 133 ICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 165
+C++R CD G NF + + +C
Sbjct: 399 VCRARMCDAHLRGPSGIITSPNFPIQYDNNAHC 431
Score = 42.7 bits (99), Expect = 3e-04
Identities = 28/85 (32%), Positives = 39/85 (45%), Gaps = 9/85 (10%)
Query: 111 YILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGY-FEGNNFTLGSTISYYCEDRY 169
+I N S+ E H + F + K C+ PG P GY GS++S+ C+ Y
Sbjct: 1188 FITDAENTSKGFELHFSS--FELIK---CEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGY 1242
Query: 170 YLVGVQEQQCVDGE---WSSALPVC 191
L G +E C+ GE W LP C
Sbjct: 1243 SLRGSEELLCLSGERRTWDRPLPTC 1267
Score = 41.6 bits (96), Expect = 7e-04
Identities = 19/54 (35%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 191
C PG P +G EG+ F G T+ + C+ + LVG + C + +WS+ P C
Sbjct: 521 CGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGC 574
Score = 41.2 bits (95), Expect = 9e-04
Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 5/58 (8%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV---DGE--WSSALPVC 191
C PG+ +G G++ LGS+++YYC Y + G C+ DG+ W++ PVC
Sbjct: 1558 CFDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVC 1615
Score = 40.4 bits (93), Expect = 0.001
Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 5/59 (8%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-----GEWSSALPVCK 192
C PG P G G++F LGS++ + C + Y L G + C+ WS PVC+
Sbjct: 343 CPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCR 401
Score = 38.5 bits (88), Expect = 0.006
Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 4/69 (5%)
Query: 127 WAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE--- 183
+A F + + C+ PG P +G G+++ G + + C+ Y L G E CV E
Sbjct: 1373 FAIQFSVSTATSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRF 1432
Query: 184 -WSSALPVC 191
W + P C
Sbjct: 1433 FWQPSPPTC 1441
Score = 37.4 bits (85), Expect = 0.013
Identities = 22/67 (32%), Positives = 36/67 (53%), Gaps = 5/67 (7%)
Query: 131 FPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYY-LVGVQEQQCVDGE----WS 185
F + +C PG PV+G G++ LGS+IS+ C++ + G + CV E W+
Sbjct: 683 FTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWN 742
Query: 186 SALPVCK 192
SA+ C+
Sbjct: 743 SAVLRCE 749
Score = 37.0 bits (84), Expect = 0.016
Identities = 19/67 (28%), Positives = 28/67 (41%), Gaps = 5/67 (7%)
Query: 131 FPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE-----WS 185
+ + S C PG +G +G+ F LG + Y C ++L G C G W
Sbjct: 131 YEVLPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWD 190
Query: 186 SALPVCK 192
LP C+
Sbjct: 191 FPLPSCR 197
Score = 35.8 bits (81), Expect = 0.037
Identities = 32/110 (29%), Positives = 43/110 (39%), Gaps = 21/110 (19%)
Query: 64 NASKEWDNTTTECRLGHCPDP--------VLVNGEFSSSGPVNVSDKITFMCNDHYILKG 115
N SK ++ + L C DP V G F+ S ++F C+ Y L+G
Sbjct: 1194 NTSKGFELHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSS-------VSFSCDPGYSLRG 1246
Query: 116 SNRSQCL--EDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISY 163
S CL E TW P P C + +C G V G G + G Y
Sbjct: 1247 SEELLCLSGERRTWDRPLPTCVA-EC---GGTVRGEVSGQVLSPGYPAPY 1292
Score = 35.4 bits (80), Expect = 0.048
Identities = 25/96 (26%), Positives = 37/96 (38%), Gaps = 3/96 (3%)
Query: 72 TTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCL--EDHTWAP 129
T +E L C +P + V D +TF C Y L+G+ R CL W+
Sbjct: 1030 TFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSS 1089
Query: 130 PFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 165
P P C + +C G NF + ++ C
Sbjct: 1090 PLPRCVA-ECGNSVTGTQGTLLSPNFPVNYNNNHEC 1124
Score = 34.3 bits (77), Expect = 0.11
Identities = 16/59 (27%), Positives = 26/59 (44%), Gaps = 2/59 (3%)
Query: 78 LGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLED--HTWAPPFPIC 134
L CP+P + + + V+D ++F C Y L+G C+ W P P+C
Sbjct: 1906 LSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLC 1964
Score = 34.3 bits (77), Expect = 0.11
Identities = 21/81 (25%), Positives = 32/81 (39%), Gaps = 2/81 (2%)
Query: 17 ASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFC--NASKEWDNTTT 74
A + + CP+ P N I T+ C+ GY L G L C ++ WD+
Sbjct: 2117 AYELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLP 2176
Query: 75 ECRLGHCPDPVLVNGEFSSSG 95
+C + + NG S G
Sbjct: 2177 KCEVPCGGNITSSNGTVYSPG 2197
Score = 32.3 bits (72), Expect = 0.40
Identities = 17/58 (29%), Positives = 26/58 (44%), Gaps = 2/58 (3%)
Query: 80 HCPDP-VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKS 136
HC DP + VNG+ V +TF C+ Y L +C + W+ P C++
Sbjct: 866 HCLDPGIPVNGQ-RHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEA 922
Score = 30.8 bits (68), Expect = 1.2
Identities = 16/62 (25%), Positives = 25/62 (40%), Gaps = 4/62 (6%)
Query: 81 CPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQC----LEDHTWAPPFPICKS 136
C +P + N+ DK+ + CN + L+G C TW P P C++
Sbjct: 139 CGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRA 198
Query: 137 RD 138
D
Sbjct: 199 DD 200
Score = 30.4 bits (67), Expect = 1.5
Identities = 16/57 (28%), Positives = 21/57 (36%), Gaps = 3/57 (5%)
Query: 81 CPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHT---WAPPFPIC 134
C DP + S D F C+ Y L+GS C++ W P P C
Sbjct: 1385 CNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTC 1441
Score = 27.7 bits (60), Expect = 9.9
Identities = 22/109 (20%), Positives = 40/109 (36%), Gaps = 8/109 (7%)
Query: 81 CPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCL----EDHTWAPPFPICKS 136
C DP + + + +T+ C+ Y ++G++ C+ W P P+C +
Sbjct: 1558 CFDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVC-T 1616
Query: 137 RDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGEWS 185
C G N+ T C Y V V + V G+++
Sbjct: 1617 APCGGQYVGSDGVVLSPNYPQNYTSGQIC---LYFVTVPKDYVVFGQFA 1662
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 96.7 bits (239), Expect = 2e-20
Identities = 55/182 (30%), Positives = 82/182 (45%), Gaps = 4/182 (2%)
Query: 23 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTT-ECRLGHC 81
C + PP+ N + E + C +GY LVG + C S +W+ + +C C
Sbjct: 2264 CGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKC 2323
Query: 82 PDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 141
P+P L+ + +TF C + ++L+G + +CL W FP+CK C P
Sbjct: 2324 PEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTP 2383
Query: 142 PGNPVHGY-FEGNNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVCKLIQEAPK 199
P G + GST+ Y C ++L G C DG WSS LP C + E P+
Sbjct: 2384 PPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPV-ECPQ 2442
Query: 200 PE 201
PE
Sbjct: 2443 PE 2444
Score = 94.7 bits (234), Expect = 7e-20
Identities = 49/170 (28%), Positives = 79/170 (46%), Gaps = 2/170 (1%)
Query: 23 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 82
CP+ + N I + + Y C G+ LVG T C + W C+ C
Sbjct: 2440 CPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIECL 2499
Query: 83 DPV-LVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 141
P ++NG+FS + ++ +T+ CN + L+G + CLE W P C + CD
Sbjct: 2500 KPKEILNGKFSYTD-LHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHCDS 2558
Query: 142 PGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGEWSSALPVC 191
P +G+ EG +++ G+ I Y C + + G Q C + WSS++P C
Sbjct: 2559 PQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESGWSSSIPTC 2608
Score = 92.8 bits (229), Expect = 3e-19
Identities = 48/156 (30%), Positives = 73/156 (46%), Gaps = 7/156 (4%)
Query: 37 KEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGP 96
KE+E Y C +G+ L G ++ C A+ W T +C C P + +
Sbjct: 2853 KEIE------YTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLD 2906
Query: 97 VNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFT 156
++TF C++ YIL G+ + C D W P+CK +C PP + HG+ G +F
Sbjct: 2907 YGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHGFPNGFSFI 2966
Query: 157 LGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVC 191
G I Y C Y L G ++C+ +G WS + P C
Sbjct: 2967 HGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSC 3002
Score = 91.3 bits (225), Expect = 7e-19
Identities = 58/215 (26%), Positives = 88/215 (40%), Gaps = 42/215 (19%)
Query: 23 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTT------EC 76
C PP++N A + TY C GY+L+G +FC + W+ + EC
Sbjct: 1690 CGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDEC 1749
Query: 77 RLG-----------------------------HCPDPVLVNGEFS-----SSGPV-NVSD 101
+G +C +P+ + SSG + V
Sbjct: 1750 AVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGA 1809
Query: 102 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTI 161
++TF C + Y L G + CLE W P CK+ C P P +G E FT GS +
Sbjct: 1810 EVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKV 1869
Query: 162 SYYCEDRYYLVGVQEQQCV-DGEWSSALPVCKLIQ 195
+Y C Y L G +E C+ + WS + PVC+ ++
Sbjct: 1870 TYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVK 1904
Score = 89.7 bits (221), Expect = 2e-18
Identities = 48/163 (29%), Positives = 72/163 (44%), Gaps = 1/163 (0%)
Query: 46 TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITF 105
T+ C +GY L+G + C S EW++ C+ C P + K+T+
Sbjct: 1812 TFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTY 1871
Query: 106 MCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 165
CN Y L G S CL + +W+ P+C+ C P N +G + + T ST SY C
Sbjct: 1872 RCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGKYILSGLTYLSTASYSC 1931
Query: 166 EDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAPKPECEKALL 207
+ Y L G +C G W A P C L+ P + A++
Sbjct: 1932 DTGYSLQGPSIIECTASGIWDRAPPACHLVFCGEPPAIKDAVI 1974
Score = 89.4 bits (220), Expect = 3e-18
Identities = 42/147 (28%), Positives = 67/147 (45%), Gaps = 1/147 (0%)
Query: 46 TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITF 105
+Y C GY L+G L C W+ + C C P F ++ + +
Sbjct: 2682 SYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMGSAVQY 2741
Query: 106 MCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 165
C +IL GS+ CLE+ W+ P C++ C P ++G +G+N+T ST+ Y C
Sbjct: 2742 SCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLSTLYYEC 2801
Query: 166 EDRYYLVGVQEQQCVDGE-WSSALPVC 191
+ Y L G + + C D + W P+C
Sbjct: 2802 DPGYVLNGTERRTCQDDKNWDEDEPIC 2828
Score = 88.2 bits (217), Expect = 6e-18
Identities = 53/182 (29%), Positives = 89/182 (48%), Gaps = 5/182 (2%)
Query: 23 CPELPPVDNSIFVAKEVEGQI-LGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHC 81
CPE P ++N + V KE+ ++ + T+ C +G+ L G L C S++W+++ C++ C
Sbjct: 2323 CPEPPLLENQL-VLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLC 2381
Query: 82 PDPVLVN-GEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCD 140
P L++ G S ++ + + C + L+G++ + C D TW+ P P C +C
Sbjct: 2382 TPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPVECP 2441
Query: 141 PPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAPK 199
P +G + ST Y C+ + LVG C +G W P CK I E K
Sbjct: 2442 QPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAI-ECLK 2500
Query: 200 PE 201
P+
Sbjct: 2501 PK 2502
Score = 88.2 bits (217), Expect = 6e-18
Identities = 47/158 (29%), Positives = 73/158 (46%), Gaps = 5/158 (3%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHC--PDPVLVNGEFSSSGPVNVSDKIT 104
Y C G+ L G C +++W + C C P+PV+ NG S +S +
Sbjct: 2741 YSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVM-NGSIKGSNYTYLST-LY 2798
Query: 105 FMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYY 164
+ C+ Y+L G+ R C +D W PIC DC P +G G+ +T I Y
Sbjct: 2799 YECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQKEIEYT 2858
Query: 165 CEDRYYLVGVQEQQCV-DGEWSSALPVCKLIQEAPKPE 201
C + + L G + + C+ +G WS A P C ++ A P+
Sbjct: 2859 CNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQ 2896
Score = 86.7 bits (213), Expect = 2e-17
Identities = 50/174 (28%), Positives = 75/174 (43%), Gaps = 4/174 (2%)
Query: 23 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHL-VGKKTLFCNASKEWDNTTTECRLGHC 81
C P V N++ + + C++GY + T C W C C
Sbjct: 3122 CGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKC 3181
Query: 82 PDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPF--PICKSRDC 139
P P + +V+ +++ C + Y +G N S C D TW PPF C C
Sbjct: 3182 PLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSDESCSPVSC 3241
Query: 140 DPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG-EWSSALPVCK 192
P +P HG+ G+ +T STI Y CE Y L G +E+ C + +WS + +CK
Sbjct: 3242 GKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICK 3295
Score = 82.0 bits (201), Expect = 4e-16
Identities = 45/188 (23%), Positives = 74/188 (39%), Gaps = 42/188 (22%)
Query: 49 CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCN 108
C G+ LVG +C +W C C P + F S+ +T+ CN
Sbjct: 1658 CDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGVPPPLENGFHSADDFYAGSTVTYQCN 1717
Query: 109 DHYILKGSNRSQCLEDHTWAPPFPICKSRD------------------------------ 138
+ Y L G +R C ++ +W P C D
Sbjct: 1718 NGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYT 1777
Query: 139 -----------CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSS 186
C PGNP +G+ G +T+G+ +++ C++ Y L+GV + C++ GEW+
Sbjct: 1778 GDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNH 1837
Query: 187 ALPVCKLI 194
+P CK +
Sbjct: 1838 LIPYCKAV 1845
Score = 82.0 bits (201), Expect = 4e-16
Identities = 50/196 (25%), Positives = 81/196 (41%), Gaps = 11/196 (5%)
Query: 38 EVEGQILG---TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-VLVNGEFSS 93
++E + G Y C +GY L G C + W + C+ CP P V+ S
Sbjct: 3311 DIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENALLS 3370
Query: 94 SGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGN 153
V ++ C + ++L+G C D TW C+ C PP + + G
Sbjct: 3371 EKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAKCEKISCGPPAHVENAIARGV 3430
Query: 154 NFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVCKLIQEAPKPECEKALLAFQES 212
++ G I+Y C Y L G C++ G W+S P+C+ + P C+ + +
Sbjct: 3431 HYQYGDMITYSCYSGYMLEGFLRSVCLENGTWTSP-PICRAVCRFP---CQNGGIC--QR 3484
Query: 213 KNLCEAMENFMQQLKE 228
N C E +M +L E
Sbjct: 3485 PNACSCPEGWMGRLCE 3500
Score = 80.5 bits (197), Expect = 1e-15
Identities = 52/194 (26%), Positives = 86/194 (44%), Gaps = 7/194 (3%)
Query: 23 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 82
C E P + N + Y C KG+++ G+K C A+ +W + C C
Sbjct: 2146 CGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVSCG 2205
Query: 83 DPVLVNGEF--SSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPI-CKSRDC 139
+P V F ++G + S+ + + CN Y GS C + W P+ C DC
Sbjct: 2206 EPPKVENGFLEHTTGRIFESE-VRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDC 2264
Query: 140 DPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWS-SALPVCKLIQEA 197
P +G+ +G NF +GS + ++C + Y LVG C G+W+ + P C + +
Sbjct: 2265 GKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKC-MPAKC 2323
Query: 198 PKPECEKALLAFQE 211
P+P + L +E
Sbjct: 2324 PEPPLLENQLVLKE 2337
Score = 79.3 bits (194), Expect = 3e-15
Identities = 43/154 (27%), Positives = 68/154 (44%), Gaps = 3/154 (1%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDP-VLVNGEFSSSGPVNVSDKITF 105
Y C GY L G + C K WD C C P V NG+ +I +
Sbjct: 2799 YECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGD-EYTFQKEIEY 2857
Query: 106 MCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 165
CN+ ++L+G+ CL + +W+ P C C P +G EG ++ ++++C
Sbjct: 2858 TCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVTFHC 2917
Query: 166 EDRYYLVGVQEQQCV-DGEWSSALPVCKLIQEAP 198
+ Y L G + C DG W + +P+CK + P
Sbjct: 2918 HEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGP 2951
Score = 77.0 bits (188), Expect = 1e-14
Identities = 46/182 (25%), Positives = 69/182 (37%), Gaps = 3/182 (1%)
Query: 6 ACCLMVAWRVSASDAE--HCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFC 63
+C +W S E C ++N ++ + +Y C GY L G + C
Sbjct: 1886 SCLANSSWSHSPPVCEPVKCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIEC 1945
Query: 64 NASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLE 123
AS WD C L C +P + + + +T+ C + Y L G + +CL
Sbjct: 1946 TASGIWDRAPPACHLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLA 2005
Query: 124 DHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDG 182
D W+ C + CD P H E + G YYC D Y L + C G
Sbjct: 2006 DGKWSRSDQQCLAVSCDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQG 2065
Query: 183 EW 184
+W
Sbjct: 2066 KW 2067
Score = 76.3 bits (186), Expect = 2e-14
Identities = 56/214 (26%), Positives = 85/214 (39%), Gaps = 22/214 (10%)
Query: 7 CCLMVAWRVSASDAEHC-------PELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKK 59
C L W SD E C PE P ++ V + + Y C GY L G +
Sbjct: 3221 CQLDGTWEPPFSD-ESCSPVSCGKPESP--EHGFVVGSKYTFESTIIYQCEPGYELEGNR 3277
Query: 60 TLFCNASKEWDNTTTECRLGHCPDPV-LVNG----EFSSSGPVNVSDKITFMCNDHYILK 114
C +++W C+ C P+ +NG E ++GP + + CN Y L+
Sbjct: 3278 ERVCQENRQWSGGVAICKETRCETPLEFLNGKADIENRTTGP-----NVVYSCNRGYSLE 3332
Query: 115 GSNRSQCLEDHTWAPPFPICKSRDCDPP-GNPVHGYFEGNNFTLGSTISYYCEDRYYLVG 173
G + + C E+ TW+ P P+CK C P P + F + +S C + + L G
Sbjct: 3333 GPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQG 3392
Query: 174 VQEQQC-VDGEWSSALPVCKLIQEAPKPECEKAL 206
C D W+ C+ I P E A+
Sbjct: 3393 HGIITCNPDETWTQTSAKCEKISCGPPAHVENAI 3426
Score = 70.9 bits (172), Expect = 1e-12
Identities = 41/171 (23%), Positives = 73/171 (42%), Gaps = 8/171 (4%)
Query: 23 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 82
C E P + +++ + TY C +GY L G T+ C A +W + +C C
Sbjct: 1963 CGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCD 2022
Query: 83 DPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPP----FPICKSRD 138
+P +V+ + D + C+D Y L +++ C W PP P C +
Sbjct: 2023 EPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAHF 2082
Query: 139 CDPPGNPVHGYFEG---NNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWS 185
C+ P + + E F GS +S+ C + + L + +C+ G+W+
Sbjct: 2083 CEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWN 2133
Score = 70.1 bits (170), Expect = 2e-12
Identities = 42/148 (28%), Positives = 63/148 (42%), Gaps = 2/148 (1%)
Query: 46 TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITF 105
T+ C +GY L G L C + WD C+ +C P + F + I +
Sbjct: 2914 TFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHGFPNGFSFIHGGHIQY 2973
Query: 106 MCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYC 165
C Y L G++ +CL + +W+ P C C P +G G +F G C
Sbjct: 2974 QCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVIE-YGTVNGTDFDCGKAARIQC 3032
Query: 166 EDRYYLVGVQEQQC-VDGEWSSALPVCK 192
+ L+G+ E C DG+WSS P C+
Sbjct: 3033 FKGFKLLGLSEITCEADGQWSSGFPHCE 3060
Score = 70.1 bits (170), Expect = 2e-12
Identities = 40/147 (27%), Positives = 57/147 (38%), Gaps = 3/147 (2%)
Query: 49 CIKGYHLVGKKTLFCNASKEWDNTTTE--CRLGHCPDPVLVNGEFSSSGPVNVSDKITFM 106
C +GY G C W+ ++ C C P F I +
Sbjct: 3207 CAEGYTFEGVNISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQ 3266
Query: 107 CNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCE 166
C Y L+G+ C E+ W+ ICK C+ P ++G + N T G + Y C
Sbjct: 3267 CEPGYELEGNRERVCQENRQWSGGVAICKETRCETPLEFLNGKADIENRTTGPNVVYSCN 3326
Query: 167 DRYYLVGVQEQQCVD-GEWSSALPVCK 192
Y L G E C + G WS +P+CK
Sbjct: 3327 RGYSLEGPSEAHCTENGTWSHPVPLCK 3353
Score = 68.9 bits (167), Expect = 4e-12
Identities = 39/155 (25%), Positives = 63/155 (40%), Gaps = 3/155 (1%)
Query: 49 CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCN 108
C KG+ L+G + C A +W + C C ++ F S + IT+ C
Sbjct: 3032 CFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPMIPNAFISETSSWKENVITYSCR 3091
Query: 109 DHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDR 168
Y+++GS+ C E W+ P+P+C+ C P + + G T S + C +
Sbjct: 3092 SGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPSVANAVATGEAHTYESEVKLRCLEG 3151
Query: 169 YYL-VGVQEQQC-VDGEWSSALPVCKLIQEAPKPE 201
Y + C DG W C ++ P PE
Sbjct: 3152 YTMDTDTDTFTCQKDGRWFPERISCS-PKKCPLPE 3185
Score = 68.6 bits (166), Expect = 5e-12
Identities = 62/228 (27%), Positives = 92/228 (40%), Gaps = 20/228 (8%)
Query: 7 CCLMVAWRVSASDAE--HCPELPPVDNSIFVAKEVEGQILGT--YVCIKGYHLVGKKTLF 62
C +R S E HCP L P +N F+ C G+ LVG +
Sbjct: 360 CVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIIL 419
Query: 63 CNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFM--CNDHYILKGSNRSQ 120
C + W + + CR+ CP S + K T + C++ Y L+GS++
Sbjct: 420 CLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLT 479
Query: 121 CLEDHTWAPPFPICKSRDCD----PPGNPVHGYFEGNNFTLGSTISYY-CEDRYYLVGVQ 175
C + W P P C R C P + + G TI Y C + L GV+
Sbjct: 480 CQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSGVK 539
Query: 176 EQ-QC-VDGEWSSAL--PVCKLIQEAPKPECEKAL----LAFQESKNL 215
E +C G+W+ + VCK + EAP+ C K + L Q+S N+
Sbjct: 540 EMLRCTTSGKWNVGVQAAVCKDV-EAPQINCPKDIEAKTLEQQDSANV 586
Score = 67.4 bits (163), Expect = 1e-11
Identities = 57/238 (23%), Positives = 85/238 (35%), Gaps = 51/238 (21%)
Query: 13 WRVSAS--DAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWD 70
W V A +A HC P++N + + Y C G+ + G C S W
Sbjct: 2544 WDVDAPSCNAIHCDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESG-WS 2602
Query: 71 NTTTECR-----------LGHC-----------------------PDP------VLVNGE 90
++ C G C P P V E
Sbjct: 2603 SSIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWE 2662
Query: 91 FSSSGPVNVSDK------ITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGN 144
+ P S +++ CN Y L G+ C ED TW P C S +CD P
Sbjct: 2663 NTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTA 2722
Query: 145 PVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG-EWSSALPVCKLIQ-EAPKP 200
P +G+ ++GS + Y C+ + L G + C++ +WS A P C+ I + P P
Sbjct: 2723 PENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNP 2780
Score = 67.0 bits (162), Expect = 1e-11
Identities = 31/106 (29%), Positives = 49/106 (46%), Gaps = 1/106 (0%)
Query: 92 SSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFE 151
++S + K+ C+ + L G+ CL W P P C+ C P +G+
Sbjct: 1643 TASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGVPPPLENGFHS 1702
Query: 152 GNNFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVCKLIQE 196
++F GST++Y C + YYL+G C D G W+ P C + E
Sbjct: 1703 ADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDE 1748
Score = 64.3 bits (155), Expect = 1e-10
Identities = 44/189 (23%), Positives = 77/189 (40%), Gaps = 9/189 (4%)
Query: 20 AEHCPELPPVDNSIFV----AKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNT--T 73
A C + P V SI AK G ++ ++ C++G+ L + C +W+ + +
Sbjct: 2080 AHFCEKPPSVSYSILESVSKAKFAAGSVV-SFKCMEGFVLNTSAKIECMRGGQWNPSPMS 2138
Query: 74 TECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPI 133
+C C +P + ++S + + + CN + +KG +S C W+ P P
Sbjct: 2139 IQCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPT 2198
Query: 134 CKSRDCDPPGNPVHGYFEGNNFTL-GSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 191
C C P +G+ E + S + Y C Y VG C + W S P+
Sbjct: 2199 CHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLM 2258
Query: 192 KLIQEAPKP 200
+ + KP
Sbjct: 2259 CVPLDCGKP 2267
Score = 62.8 bits (151), Expect = 3e-10
Identities = 52/217 (23%), Positives = 71/217 (32%), Gaps = 54/217 (24%)
Query: 46 TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITF 105
TY C +G+ L G L C + +WD C HC P + F + I +
Sbjct: 2521 TYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYSYGAIIIY 2580
Query: 106 MCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVH-------------GYFE- 151
C + + G C E+ W+ P C DC G P H GYFE
Sbjct: 2581 SCFPGFQVAGHAMQTC-EESGWSSSIPTCMPIDC---GLPPHIDFGDCTKLKDDQGYFEQ 2636
Query: 152 -----------------------------------GNNFTLGSTISYYCEDRYYLVGVQE 176
+NF G+ +SY C Y L+G
Sbjct: 2637 EDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPV 2696
Query: 177 QQC-VDGEWSSALPVCKLIQEAPKPECEKALLAFQES 212
C DG W+ + P C I+ E L F E+
Sbjct: 2697 LICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTET 2733
Score = 62.0 bits (149), Expect = 5e-10
Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 1/107 (0%)
Query: 30 DNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNG 89
+N++ KE + C +G+ L G + CN + W T+ +C C P V
Sbjct: 3365 ENALLSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAKCEKISCGPPAHVEN 3424
Query: 90 EFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKS 136
+ D IT+ C Y+L+G RS CLE+ TW P PIC++
Sbjct: 3425 AIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWTSP-PICRA 3470
Score = 61.6 bits (148), Expect = 6e-10
Identities = 37/161 (22%), Positives = 61/161 (37%), Gaps = 2/161 (1%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFM 106
Y C GY L G + C ++ W ++ C C PV+ G + + +
Sbjct: 2973 YQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVIEYGTVNGT-DFDCGKAARIQ 3031
Query: 107 CNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCE 166
C + L G + C D W+ FP C+ C + + + + I+Y C
Sbjct: 3032 CFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPMIPNAFISETSSWKENVITYSCR 3091
Query: 167 DRYYLVGVQEQQCVD-GEWSSALPVCKLIQEAPKPECEKAL 206
Y + G + C + G WS PVC+ + P A+
Sbjct: 3092 SGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPSVANAV 3132
Score = 35.4 bits (80), Expect = 0.048
Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 2/68 (2%)
Query: 138 DCDPPGNPV-HGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVCKLIQ 195
DC G V H + GS ++ +C+ + LVG Q C++ G+W+ LP C+ I
Sbjct: 1630 DCPRLGGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERIS 1689
Query: 196 EAPKPECE 203
P E
Sbjct: 1690 CGVPPPLE 1697
Score = 29.3 bits (64), Expect = 3.4
Identities = 17/49 (34%), Positives = 21/49 (42%), Gaps = 16/49 (32%)
Query: 133 ICKSRDCDPPGNPVHGYF----------------EGNNFTLGSTISYYC 165
+ K C+ P PV+G F EG +FT GST YYC
Sbjct: 721 VIKGSPCEIPFTPVNGDFICTPDNTGVNCTLTCLEGYDFTEGSTDKYYC 769
>gi|54792123 complement component (3d/Epstein Barr virus) receptor 2
isoform 1 [Homo sapiens]
Length = 1092
Score = 90.5 bits (223), Expect = 1e-18
Identities = 59/194 (30%), Positives = 87/194 (44%), Gaps = 26/194 (13%)
Query: 23 CPELPPVDNSIFVAKEVEGQILGT---YVCIKG------YHLVGKKTLFCNASKE----W 69
CP P + N +E GT Y C G + L+G+ T+ C ++ + W
Sbjct: 527 CPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTW 586
Query: 70 DNTTTECRLG----HCPDPVLVNGEFSSSG---PVNVSDKITFMCNDHYILKGSNRSQCL 122
C+L C + NG + SG P +D +TF C + LKGS++ +C
Sbjct: 587 SGPAPLCKLSLLAVQCSHVHIANG-YKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCK 645
Query: 123 EDHTWAPPFPICKSRDCDPPGNPVHGYFEGNN---FTLGSTISYYCEDRYYLVGVQEQQC 179
D+TW P P+C+ + C P HG G N F G T+ Y C+ Y LVG + C
Sbjct: 646 ADNTWDPEIPVCE-KGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHC 704
Query: 180 V-DGEWSSALPVCK 192
+ G WS + P C+
Sbjct: 705 MPSGNWSPSAPRCE 718
Score = 89.7 bits (221), Expect = 2e-18
Identities = 59/207 (28%), Positives = 90/207 (43%), Gaps = 25/207 (12%)
Query: 11 VAW-RVSASDAEHCPELPPVDNSIFVAKEVEGQILG---TYVCIK------GYHLVGKKT 60
VAW ++ + CP PP+ N + + G TY C + L+G+ T
Sbjct: 263 VAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGEST 322
Query: 61 LFCNASKE----WDNTTTECRLG----HCPDPVLVNGEFSSSGP--VNVSDKITFMCNDH 110
L C + W C L CP P ++ G S +D + F C
Sbjct: 323 LRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFG 382
Query: 111 YILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNN---FTLGSTISYYCED 167
+ LKGS + +C TW P P+C+ ++C P N ++G E + F G++I Y C
Sbjct: 383 FTLKGSKQIRCNAQGTWEPSAPVCE-KECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNP 441
Query: 168 RYYLVGVQEQQCV-DGEWSSALPVCKL 193
Y LVG + QC +G W+ +P CK+
Sbjct: 442 GYVLVGEESIQCTSEGVWTPPVPQCKV 468
Score = 83.2 bits (204), Expect = 2e-16
Identities = 55/191 (28%), Positives = 85/191 (44%), Gaps = 20/191 (10%)
Query: 22 HCPELPPVDNSIFVAKEVEGQILG---TYVCIKGYHLVGKKTLFCNASKE----WDNTTT 74
HC P + N E + G +Y C +G++L+G+K L C + + W +
Sbjct: 777 HCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSP 836
Query: 75 ECR----LGHCPDPVLVNGEF--SSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWA 128
+C + CP+P + +G + + +D + CN +I+ GS +C D+TW
Sbjct: 837 QCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWV 896
Query: 129 PPFPICKSR---DCDPPGNPVHGYFEGNN---FTLGSTISYYCEDRYYLVGVQEQQCV-D 181
P P C + C PP +G G N F+ G +I Y C+ Y LVG C +
Sbjct: 897 PGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHE 956
Query: 182 GEWSSALPVCK 192
G WS P CK
Sbjct: 957 GTWSQPAPHCK 967
Score = 74.7 bits (182), Expect = 7e-14
Identities = 51/168 (30%), Positives = 68/168 (40%), Gaps = 17/168 (10%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFM 106
Y C GY LVG K++ C S W + C C E + V + +
Sbjct: 688 YTCDPGYLLVGNKSIHCMPSGNWSPSAPRCE-ETCQHVRQSLQELPAGSRVEL---VNTS 743
Query: 107 CNDHYILKGSNRSQC--LEDHTWAPPFPICKSRDCDPPGNPVHGYFEG---NNFTLGSTI 161
C D Y L G C E+ W P+CK C PP V+G G NF G+ +
Sbjct: 744 CQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEV 803
Query: 162 SYYCEDRYYLVGVQEQQCVD-----GEWSSALPVC---KLIQEAPKPE 201
SY C+ +YL+G ++ QC G WS P C + P PE
Sbjct: 804 SYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPE 851
Score = 73.9 bits (180), Expect = 1e-13
Identities = 56/203 (27%), Positives = 84/203 (41%), Gaps = 25/203 (12%)
Query: 23 CPELPPVDNSIFVAKEVEGQILG---TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLG 79
CP LP + N ++ V G TY C GY LVG+K + C +S +W C
Sbjct: 154 CPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEA 213
Query: 80 HCPD-PVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCL---EDHTWAPPFPICK 135
C NG+ + V F C++ Y L+G S+C+ + W P+C+
Sbjct: 214 RCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWT-KMPVCE 272
Query: 136 SRDCDPPGNPVHGYFEGN---NFTLGSTISYYCED------RYYLVGVQEQQCV-----D 181
C P ++G GN N + GS ++Y C+ + L+G +C
Sbjct: 273 EIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKT 332
Query: 182 GEWSSALPVCKLIQEA---PKPE 201
G WS P C+L A P P+
Sbjct: 333 GTWSGPAPRCELSTSAVQCPHPQ 355
Score = 73.6 bits (179), Expect = 2e-13
Identities = 51/190 (26%), Positives = 85/190 (44%), Gaps = 21/190 (11%)
Query: 23 CPELPPVDN---SIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKE----WDNTTTE 75
C PP+ N S + G ++ Y C + L+G+K+L C + WD +
Sbjct: 23 CGSPPPILNGRISYYSTPIAVGTVI-RYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 76 C----RLGHCPDPVLVNG-EFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPP 130
C + CP+P++ G + S P D +TF C ++ + G+ C ++ W P
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPT 141
Query: 131 -FPICKS-RDCDPPGNPV--HGYFEGNN---FTLGSTISYYCEDRYYLVGVQEQQCV-DG 182
P C S + P P+ +G+ N G +++Y CE Y LVG + C+ G
Sbjct: 142 RLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSG 201
Query: 183 EWSSALPVCK 192
+WS+ P C+
Sbjct: 202 KWSAVPPTCE 211
Score = 71.2 bits (173), Expect = 8e-13
Identities = 34/98 (34%), Positives = 47/98 (47%), Gaps = 3/98 (3%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDK---I 103
Y C +GY LVG+ L C W C+ +C P ++G P + +
Sbjct: 937 YSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVV 996
Query: 104 TFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 141
T C D Y+L+GS +SQC DH W PP +C+SR P
Sbjct: 997 TLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAP 1034
Score = 69.7 bits (169), Expect = 2e-12
Identities = 44/162 (27%), Positives = 65/162 (40%), Gaps = 15/162 (9%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSD--KIT 104
+ C+ G+ L G K + CNA W+ + C P ++NG+ V I
Sbjct: 377 FACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIK 436
Query: 105 FMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPG-----NPVHGYFEGNNFTLGS 159
+ CN Y+L G QC + W PP P CK C+ G P H + +
Sbjct: 437 YSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPD------ 490
Query: 160 TISYYCEDRYYLVGVQEQQCVDG-EWSSALPVCKLIQEAPKP 200
++ C + Y L G Q+C W + +CK I P P
Sbjct: 491 -VNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPP 531
Score = 68.9 bits (167), Expect = 4e-12
Identities = 44/161 (27%), Positives = 68/161 (42%), Gaps = 12/161 (7%)
Query: 49 CIKGYHLVGKKTLFCNASKEWDNTTTECR----LGHCPDPVLVNGEFSSSGPVNVSD--K 102
C G+ + G + + C+ W C +G P P NG + S
Sbjct: 875 CNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMS 934
Query: 103 ITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEG----NNFTLG 158
I + C+ Y+L G C + TW+ P P CK +C P + + G +G + G
Sbjct: 935 ILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPAD-MDGIQKGLEPRKMYQYG 993
Query: 159 STISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAP 198
+ ++ CED Y L G + QC D +W+ L VC+ AP
Sbjct: 994 AVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAP 1034
Score = 65.9 bits (159), Expect = 3e-11
Identities = 55/209 (26%), Positives = 82/209 (39%), Gaps = 28/209 (13%)
Query: 7 CCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQIL---GT---YVCIKGYHLVGKKT 60
C W SA E + PP N + KE + GT Y C GY LVG+++
Sbjct: 393 CNAQGTWEPSAPVCEKECQAPP--NILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEES 450
Query: 61 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVN--VSDKITFMCNDHYILKGSNR 118
+ C + W +C++ C G + P + V + C + Y L GS
Sbjct: 451 IQCTSEGVWTPPVPQCKVAACE----ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVY 506
Query: 119 SQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGN---NFTLGSTISYYCED------RY 169
+C W +CK C PP +G G+ +F G+T++Y C +
Sbjct: 507 QECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEF 566
Query: 170 YLVGVQEQQCVD-----GEWSSALPVCKL 193
L+G +C G WS P+CKL
Sbjct: 567 SLIGESTIRCTSNDQERGTWSGPAPLCKL 595
>gi|42544177 complement component (3d/Epstein Barr virus) receptor 2
isoform 2 [Homo sapiens]
Length = 1033
Score = 89.7 bits (221), Expect = 2e-18
Identities = 59/207 (28%), Positives = 90/207 (43%), Gaps = 25/207 (12%)
Query: 11 VAW-RVSASDAEHCPELPPVDNSIFVAKEVEGQILG---TYVCIK------GYHLVGKKT 60
VAW ++ + CP PP+ N + + G TY C + L+G+ T
Sbjct: 263 VAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGEST 322
Query: 61 LFCNASKE----WDNTTTECRLG----HCPDPVLVNGEFSSSGP--VNVSDKITFMCNDH 110
L C + W C L CP P ++ G S +D + F C
Sbjct: 323 LRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFG 382
Query: 111 YILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNN---FTLGSTISYYCED 167
+ LKGS + +C TW P P+C+ ++C P N ++G E + F G++I Y C
Sbjct: 383 FTLKGSKQIRCNAQGTWEPSAPVCE-KECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNP 441
Query: 168 RYYLVGVQEQQCV-DGEWSSALPVCKL 193
Y LVG + QC +G W+ +P CK+
Sbjct: 442 GYVLVGEESIQCTSEGVWTPPVPQCKV 468
Score = 85.5 bits (210), Expect = 4e-17
Identities = 58/201 (28%), Positives = 86/201 (42%), Gaps = 27/201 (13%)
Query: 23 CPELPPVDNSIFVAKEVEGQILGT---YVCIKG------YHLVGKKTLFCNASKE----W 69
CP P + N +E GT Y C G + L+G+ T+ C ++ + W
Sbjct: 527 CPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTW 586
Query: 70 DNTTTECRLG----HCPDPVLVNGEFSSSG---PVNVSDKITFMCNDHYILKGSNRSQCL 122
C+L C + NG + SG P +D +TF C + LKGS++ +C
Sbjct: 587 SGPAPLCKLSLLAVQCSHVHIANG-YKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCK 645
Query: 123 EDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG 182
D+TW P P+C+ C + G+ L +T C+D Y L G Q C D
Sbjct: 646 ADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVELVNT---SCQDGYQLTGHAYQMCQDA 702
Query: 183 E---WSSALPVCKLIQEAPKP 200
E W +P+CK+I P P
Sbjct: 703 ENGIWFKKIPLCKVIHCHPPP 723
Score = 83.2 bits (204), Expect = 2e-16
Identities = 55/191 (28%), Positives = 85/191 (44%), Gaps = 20/191 (10%)
Query: 22 HCPELPPVDNSIFVAKEVEGQILG---TYVCIKGYHLVGKKTLFCNASKE----WDNTTT 74
HC P + N E + G +Y C +G++L+G+K L C + + W +
Sbjct: 718 HCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSP 777
Query: 75 ECR----LGHCPDPVLVNGEF--SSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWA 128
+C + CP+P + +G + + +D + CN +I+ GS +C D+TW
Sbjct: 778 QCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWV 837
Query: 129 PPFPICKSR---DCDPPGNPVHGYFEGNN---FTLGSTISYYCEDRYYLVGVQEQQCV-D 181
P P C + C PP +G G N F+ G +I Y C+ Y LVG C +
Sbjct: 838 PGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHE 897
Query: 182 GEWSSALPVCK 192
G WS P CK
Sbjct: 898 GTWSQPAPHCK 908
Score = 74.3 bits (181), Expect = 9e-14
Identities = 49/169 (28%), Positives = 66/169 (39%), Gaps = 16/169 (9%)
Query: 46 TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITF 105
T+ C G+ L G + C A WD C C E + V + +
Sbjct: 627 TFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVEL---VNT 683
Query: 106 MCNDHYILKGSNRSQC--LEDHTWAPPFPICKSRDCDPPGNPVHGYFEG---NNFTLGST 160
C D Y L G C E+ W P+CK C PP V+G G NF G+
Sbjct: 684 SCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNE 743
Query: 161 ISYYCEDRYYLVGVQEQQCVD-----GEWSSALPVC---KLIQEAPKPE 201
+SY C+ +YL+G ++ QC G WS P C + P PE
Sbjct: 744 VSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPE 792
Score = 73.9 bits (180), Expect = 1e-13
Identities = 56/203 (27%), Positives = 84/203 (41%), Gaps = 25/203 (12%)
Query: 23 CPELPPVDNSIFVAKEVEGQILG---TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLG 79
CP LP + N ++ V G TY C GY LVG+K + C +S +W C
Sbjct: 154 CPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEA 213
Query: 80 HCPD-PVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCL---EDHTWAPPFPICK 135
C NG+ + V F C++ Y L+G S+C+ + W P+C+
Sbjct: 214 RCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWT-KMPVCE 272
Query: 136 SRDCDPPGNPVHGYFEGN---NFTLGSTISYYCED------RYYLVGVQEQQCV-----D 181
C P ++G GN N + GS ++Y C+ + L+G +C
Sbjct: 273 EIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKT 332
Query: 182 GEWSSALPVCKLIQEA---PKPE 201
G WS P C+L A P P+
Sbjct: 333 GTWSGPAPRCELSTSAVQCPHPQ 355
Score = 73.6 bits (179), Expect = 2e-13
Identities = 51/190 (26%), Positives = 85/190 (44%), Gaps = 21/190 (11%)
Query: 23 CPELPPVDN---SIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKE----WDNTTTE 75
C PP+ N S + G ++ Y C + L+G+K+L C + WD +
Sbjct: 23 CGSPPPILNGRISYYSTPIAVGTVI-RYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 76 C----RLGHCPDPVLVNG-EFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPP 130
C + CP+P++ G + S P D +TF C ++ + G+ C ++ W P
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPT 141
Query: 131 -FPICKS-RDCDPPGNPV--HGYFEGNN---FTLGSTISYYCEDRYYLVGVQEQQCV-DG 182
P C S + P P+ +G+ N G +++Y CE Y LVG + C+ G
Sbjct: 142 RLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSG 201
Query: 183 EWSSALPVCK 192
+WS+ P C+
Sbjct: 202 KWSAVPPTCE 211
Score = 71.2 bits (173), Expect = 8e-13
Identities = 34/98 (34%), Positives = 47/98 (47%), Gaps = 3/98 (3%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDK---I 103
Y C +GY LVG+ L C W C+ +C P ++G P + +
Sbjct: 878 YSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVV 937
Query: 104 TFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 141
T C D Y+L+GS +SQC DH W PP +C+SR P
Sbjct: 938 TLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAP 975
Score = 69.7 bits (169), Expect = 2e-12
Identities = 44/162 (27%), Positives = 65/162 (40%), Gaps = 15/162 (9%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSD--KIT 104
+ C+ G+ L G K + CNA W+ + C P ++NG+ V I
Sbjct: 377 FACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIK 436
Query: 105 FMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPG-----NPVHGYFEGNNFTLGS 159
+ CN Y+L G QC + W PP P CK C+ G P H + +
Sbjct: 437 YSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPD------ 490
Query: 160 TISYYCEDRYYLVGVQEQQCVDG-EWSSALPVCKLIQEAPKP 200
++ C + Y L G Q+C W + +CK I P P
Sbjct: 491 -VNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPP 531
Score = 68.9 bits (167), Expect = 4e-12
Identities = 44/161 (27%), Positives = 68/161 (42%), Gaps = 12/161 (7%)
Query: 49 CIKGYHLVGKKTLFCNASKEWDNTTTECR----LGHCPDPVLVNGEFSSSGPVNVSD--K 102
C G+ + G + + C+ W C +G P P NG + S
Sbjct: 816 CNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMS 875
Query: 103 ITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEG----NNFTLG 158
I + C+ Y+L G C + TW+ P P CK +C P + + G +G + G
Sbjct: 876 ILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPAD-MDGIQKGLEPRKMYQYG 934
Query: 159 STISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAP 198
+ ++ CED Y L G + QC D +W+ L VC+ AP
Sbjct: 935 AVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAP 975
Score = 65.9 bits (159), Expect = 3e-11
Identities = 55/209 (26%), Positives = 82/209 (39%), Gaps = 28/209 (13%)
Query: 7 CCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQIL---GT---YVCIKGYHLVGKKT 60
C W SA E + PP N + KE + GT Y C GY LVG+++
Sbjct: 393 CNAQGTWEPSAPVCEKECQAPP--NILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEES 450
Query: 61 LFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVN--VSDKITFMCNDHYILKGSNR 118
+ C + W +C++ C G + P + V + C + Y L GS
Sbjct: 451 IQCTSEGVWTPPVPQCKVAACE----ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVY 506
Query: 119 SQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGN---NFTLGSTISYYCED------RY 169
+C W +CK C PP +G G+ +F G+T++Y C +
Sbjct: 507 QECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEF 566
Query: 170 YLVGVQEQQCVD-----GEWSSALPVCKL 193
L+G +C G WS P+CKL
Sbjct: 567 SLIGESTIRCTSNDQERGTWSGPAPLCKL 595
>gi|67782358 complement factor B preproprotein [Homo sapiens]
Length = 764
Score = 88.2 bits (217), Expect = 6e-18
Identities = 60/189 (31%), Positives = 87/189 (46%), Gaps = 17/189 (8%)
Query: 40 EGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTT---------ECRLGHCPDPV-LVNG 89
EGQ L YVC G++ +T C ++ W T ECR HCP P NG
Sbjct: 54 EGQAL-EYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENG 112
Query: 90 EFSSSGPV-NVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRD--CDPPGNPV 146
E+ P NVSD+I+F C D Y L+GS C + W+ IC + C PG P+
Sbjct: 113 EYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPI 172
Query: 147 HGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVCK--LIQEAPKPECE 203
G+ + L +++Y+C L G Q + C + G WS P C+ + + P+ E
Sbjct: 173 GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTPQEVAE 232
Query: 204 KALLAFQES 212
L + E+
Sbjct: 233 AFLSSLTET 241
Score = 52.8 bits (125), Expect = 3e-07
Identities = 32/122 (26%), Positives = 50/122 (40%), Gaps = 8/122 (6%)
Query: 20 AEHCPELPPVDNSIFVAKE----VEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTE 75
A HCP +N + + V +I ++ C GY L G C + W T
Sbjct: 100 AIHCPRPHDFENGEYWPRSPYYNVSDEI--SFHCYDGYTLRGSANRTCQVNGRWSGQTAI 157
Query: 76 CR--LGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPI 133
C G+C +P + G + D +T+ C+ L+GS R C E +W+ P
Sbjct: 158 CDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPS 217
Query: 134 CK 135
C+
Sbjct: 218 CQ 219
>gi|187960042 selectin E precursor [Homo sapiens]
Length = 610
Score = 86.7 bits (213), Expect = 2e-17
Identities = 44/161 (27%), Positives = 71/161 (44%), Gaps = 11/161 (6%)
Query: 46 TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHC-----PDPVLVNGEFSSSGPVNVS 100
T+ C +G+ L+G ++L C +S WDN C+ C P V S +G
Sbjct: 269 TFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFK 328
Query: 101 DKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFE-----GNNF 155
F C + ++L+G + +C W P+C++ C NP GY +F
Sbjct: 329 SSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSF 388
Query: 156 TLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQ 195
GS+ + CE + L G + QC GEW + P C+ ++
Sbjct: 389 RYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVR 429
Score = 71.2 bits (173), Expect = 8e-13
Identities = 41/160 (25%), Positives = 68/160 (42%), Gaps = 11/160 (6%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHC-----PDPVLVNGEFSSSGPVNVSD 101
+ C +G+ L G + C +W C C P+ +N S+SG
Sbjct: 333 FTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGS 392
Query: 102 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHG-----YFEGNNFT 156
F C ++LKGS R QC W P C++ CD P G + FT
Sbjct: 393 SCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFT 452
Query: 157 LGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVCKLIQ 195
S+ ++ CE+ + L G + +C G+W+ +P C++++
Sbjct: 453 YKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVK 492
Score = 68.9 bits (167), Expect = 4e-12
Identities = 44/158 (27%), Positives = 68/158 (43%), Gaps = 12/158 (7%)
Query: 49 CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVL--VNGE---FSSSGPVNVSDKI 103
C +GY +T+ C +S EW C + C D V NG F + G +
Sbjct: 210 CDRGYLPSSMETMQCMSSGEWSAPIPACNVVEC-DAVTNPANGFVECFQNPGSFPWNTTC 268
Query: 104 TFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHG-----YFEGNNFTLG 158
TF C + + L G+ QC W P CK+ C P +G + FT
Sbjct: 269 TFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFK 328
Query: 159 STISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQ 195
S+ ++ CE+ + L G + +C G+W+ +PVC+ Q
Sbjct: 329 SSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQ 366
Score = 65.1 bits (157), Expect = 6e-11
Identities = 43/162 (26%), Positives = 61/162 (37%), Gaps = 9/162 (5%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHC-----PDPVLVNGEFSSSGPVNVSD 101
+ C +G+ L G K L C + EWDN C C P LV S G
Sbjct: 396 FSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKS 455
Query: 102 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNP--VHGYFEGNNFTLGS 159
F C + + L GS + +C W P C+ C P ++ G G+
Sbjct: 456 SCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEP-VFGT 514
Query: 160 TISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAPKP 200
+ C + + L G + C G WS LP C+ E+ P
Sbjct: 515 VCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESNIP 556
Score = 64.7 bits (156), Expect = 7e-11
Identities = 34/119 (28%), Positives = 54/119 (45%), Gaps = 14/119 (11%)
Query: 81 CPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCD 140
C P+ G FS + ++S C+ Y+ QC+ W+ P P C +CD
Sbjct: 193 CSHPL---GNFSYNSSCSIS------CDRGYLPSSMETMQCMSSGEWSAPIPACNVVECD 243
Query: 141 PPGNPVHGYFE----GNNFTLGSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVCKLI 194
NP +G+ E +F +T ++ CE+ + L+G Q QC G W + P CK +
Sbjct: 244 AVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAV 302
>gi|32261332 seizure related 6 homolog (mouse)-like precursor [Homo
sapiens]
Length = 1024
Score = 84.0 bits (206), Expect = 1e-16
Identities = 61/216 (28%), Positives = 97/216 (44%), Gaps = 19/216 (8%)
Query: 15 VSASDAEHCPELPPVDNSIFVAKEVEGQILG---TYVCIKGYHLVGKKTLFCNASKEWDN 71
+ S + C +LP + N E + G TY C GY +VG TL C W +
Sbjct: 737 IEVSRNDSCSDLPEIQNGWKTTSHTE-LVRGARITYQCDPGYDIVGSDTLTCQWDLSWSS 795
Query: 72 TTTEC-RLGHCPDPVLV--NGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHT-- 126
C ++ +C DP V + S + V I + CN ++L+GS+ C T
Sbjct: 796 DPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGT 855
Query: 127 --WAPPFPICKSRD---CDPPGNPVHGY--FEGNNFTLGSTISYYCEDRYYLVGVQEQQC 179
W P C S + CD PG P +GY + G ++++ C + + L+G +C
Sbjct: 856 PIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRC 915
Query: 180 VDGE---WSSALPVCKLIQEAPKPECEKALLAFQES 212
+ G+ W+ LPVCK+ Q++ + E A A + S
Sbjct: 916 ILGQPSHWNGPLPVCKVNQDSFEHALEVAEAAAETS 951
Score = 37.7 bits (86), Expect = 0.010
Identities = 19/62 (30%), Positives = 33/62 (53%), Gaps = 4/62 (6%)
Query: 79 GHCPDPVLVNGEFSSSGPV-NVSDKITFMCN-DHYILKGSNRSQCL--EDHTWAPPFPIC 134
GHC +P + NG F++S P N+ + F C+ H + +G +C+ D W P+C
Sbjct: 565 GHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLC 624
Query: 135 KS 136
++
Sbjct: 625 RA 626
Score = 28.1 bits (61), Expect = 7.6
Identities = 15/56 (26%), Positives = 23/56 (41%), Gaps = 3/56 (5%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVC 191
C+ P P G + G ++C Y L G + C++ WSS P+C
Sbjct: 393 CNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPIC 448
>gi|157419154 selectin P precursor [Homo sapiens]
Length = 830
Score = 80.5 bits (197), Expect = 1e-15
Identities = 54/195 (27%), Positives = 78/195 (40%), Gaps = 17/195 (8%)
Query: 46 TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPD-PVLVNGEFS---SSGPVNVSD 101
++ C GY + G L C AS W N +C CP + G + S+
Sbjct: 227 SFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQS 286
Query: 102 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEG----NNFTL 157
+F C + + L G QC W P P+CK+ C P G + F
Sbjct: 287 SCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAY 346
Query: 158 GSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVCKLIQEAP-------KPECEKALLAF 209
GS+ + C+ Y + G+ +C+D G WS+ LP C+ I P +C +L AF
Sbjct: 347 GSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAF 406
Query: 210 QESKNLC-EAMENFM 223
Q N E FM
Sbjct: 407 QYDTNCSFRCAEGFM 421
Score = 77.0 bits (188), Expect = 1e-14
Identities = 49/169 (28%), Positives = 76/169 (44%), Gaps = 11/169 (6%)
Query: 42 QILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVL--VNGEFSSSGPVNV 99
Q + ++ C +G LVG L C A+ W++ EC+ C P+L NG + P+
Sbjct: 471 QSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPC-TPLLSPQNGTMTCVQPLGS 529
Query: 100 S---DKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNN-- 154
S F+C++ Y L G R C W P+C++ C P G + ++
Sbjct: 530 SSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTR 589
Query: 155 --FTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAPKP 200
F +GST + C++ + L G +C G WS+ P CK I P P
Sbjct: 590 GEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTP 638
Score = 76.3 bits (186), Expect = 2e-14
Identities = 49/194 (25%), Positives = 87/194 (44%), Gaps = 23/194 (11%)
Query: 20 AEHCPELPPVDNS----IFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTE 75
A CP L + + AK + Q ++ C +G+ LVG + + C AS W
Sbjct: 259 AAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPV 318
Query: 76 CRLGHCPDPVLVNGEFSSSGPVNVSDKIT---------FMCNDHYILKGSNRSQCLEDHT 126
C+ C + E S G ++ +T F C Y ++G + +C++
Sbjct: 319 CKAVQCQ-----HLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGH 373
Query: 127 WAPPFPICKSRDCDPPGNPVHGYFEGN----NFTLGSTISYYCEDRYYLVGVQEQQCVD- 181
W+ P P C++ C+P +PVHG + + F + S+ C + + L G +C +
Sbjct: 374 WSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNL 433
Query: 182 GEWSSALPVCKLIQ 195
G+W++ PVC+ +Q
Sbjct: 434 GQWTAPAPVCQALQ 447
Score = 63.2 bits (152), Expect = 2e-10
Identities = 45/147 (30%), Positives = 64/147 (43%), Gaps = 13/147 (8%)
Query: 75 ECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPIC 134
EC P VL+N G + + + +F C D Y + G ++ +CL W P C
Sbjct: 199 ECGELELPQHVLMNCSHPL-GNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Query: 135 KSRDCDPPGNPVHG----YFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALP 189
+ C P P G F S+ S+ CE+ + LVG + QC G W++ P
Sbjct: 258 LAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAP 317
Query: 190 VCKLIQ----EAPKP---ECEKALLAF 209
VCK +Q EAP +C L AF
Sbjct: 318 VCKAVQCQHLEAPSEGTMDCVHPLTAF 344
Score = 62.0 bits (149), Expect = 5e-10
Identities = 40/159 (25%), Positives = 69/159 (43%), Gaps = 9/159 (5%)
Query: 46 TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPD-PVLVNGEFSSSGPVNV---SD 101
++ C +G+ L G + C+ +W C+ C D PV + S P
Sbjct: 413 SFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQS 472
Query: 102 KITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEG----NNFTL 157
+F CN+ +L G++ QCL W P C++ C P +P +G + +
Sbjct: 473 VCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSY 532
Query: 158 GSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVCKLIQ 195
ST + C++ Y L G + C G W+ + P+C+ I+
Sbjct: 533 KSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIK 571
Score = 60.5 bits (145), Expect = 1e-09
Identities = 40/166 (24%), Positives = 63/166 (37%), Gaps = 17/166 (10%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVL-VNGEFSSS---GPVNVSDK 102
++C +GY L G + L C S W ++ C CP+ G S G NV
Sbjct: 538 FICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGST 597
Query: 103 ITFMCNDHYILKGSNRSQCLEDHTWAPPFPICK--------SRDCDPPGNPVHGYF---- 150
F C++ + L+G N +C W+ P CK C P G
Sbjct: 598 CHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRH 657
Query: 151 EGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQ 195
F +T + C + L+G C G+W++ P C+ ++
Sbjct: 658 HPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVK 703
Score = 55.5 bits (132), Expect = 4e-08
Identities = 48/204 (23%), Positives = 78/204 (38%), Gaps = 25/204 (12%)
Query: 19 DAEHCPELPPVDNSIFVAKEVEGQI-LGT---YVCIKGYHLVGKKTLFCNASKEWDNTTT 74
+A CPEL + + G+ +G+ + C G+ L G + C S W T
Sbjct: 568 EAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPP 627
Query: 75 ECR-LGHCPDPVLVNGEFSSSGPVNV-----------SDKITFMCNDHYILKGSNRSQCL 122
C+ + P P + ++ G + + F CN + L G + C
Sbjct: 628 TCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCR 687
Query: 123 EDHTWAPPFPICKSRDCDP--PGNPVHGYFEG--NNFTLGSTISYYCEDRYYLVGVQEQQ 178
W P C++ C P+ NF+ GS S++C + L G +
Sbjct: 688 PSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQTA 747
Query: 179 CVD-GEWSSALPVCK----LIQEA 197
C + G WS+ +P C+ IQEA
Sbjct: 748 CQENGHWSTTVPTCQAGPLTIQEA 771
>gi|148922949 complement component (3b/4b) receptor 1-like [Homo
sapiens]
Length = 569
Score = 79.7 bits (195), Expect = 2e-15
Identities = 45/158 (28%), Positives = 72/158 (45%), Gaps = 10/158 (6%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPV--LVNGEFSSSGPVNVSDKIT 104
Y C GY L G L C +W C + C D + L NG + + K+
Sbjct: 316 YSCEPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFPLNLQLGAKVD 375
Query: 105 FMCNDHYILKGSNRSQCL---EDHTWAPPFPICKSRDCDPPGNPVHGYFEG-NNFTLGST 160
F+C++ + LKGS+ S C+ + W P+C+ + C+ P PV+G + +GS
Sbjct: 376 FVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIHVGSR 435
Query: 161 ISYYCEDRYYLVGVQEQQCV----DGEWSSALPVCKLI 194
I+Y C + L+G +C+ WS P+C+ I
Sbjct: 436 INYSCTTGHRLIGHSSAECILSGNTAHWSMKPPICQQI 473
Score = 67.8 bits (164), Expect = 9e-12
Identities = 46/181 (25%), Positives = 77/181 (42%), Gaps = 19/181 (10%)
Query: 27 PPVDNSIFVAKEVEGQILGTYV---CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPD 83
P V+N I V+ L V C G+ + G + C A +W+ C P
Sbjct: 233 PNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSRVCQPP 292
Query: 84 PVLVNGEFSSSGPVNVS--DKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCD- 140
P +++ E + N S ++ + C Y L+GS C W+P P C+ + CD
Sbjct: 293 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCDD 352
Query: 141 -----PPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV----DGEWSSALPVC 191
P G+ + N LG+ + + C++ + L G CV + W+S++PVC
Sbjct: 353 FLGQLPNGHVLFPL----NLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVC 408
Query: 192 K 192
+
Sbjct: 409 E 409
Score = 61.6 bits (148), Expect = 6e-10
Identities = 62/240 (25%), Positives = 94/240 (39%), Gaps = 27/240 (11%)
Query: 8 CLMVAWRVSASDA---EHCPELP-PVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFC 63
CL + SA D + C P PV+ V K+++ + Y C KGY L+G + C
Sbjct: 78 CLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATC 137
Query: 64 NASKE---WDNTTTECRLGHCP-DPVLVNGEFSSSGP--VNVSDKITFMCN------DHY 111
S WDN T C C P + NG+F+S + +T+ CN +
Sbjct: 138 IISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVF 197
Query: 112 ILKGSNRSQCLEDH----TWAPPFPIC-KSRDCDPPGNPVHGYFEGNN---FTLGSTISY 163
L G C W+ P P C C PP N +G +N F+L + +
Sbjct: 198 ELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCTPP-NVENGILVSDNRSLFSLNEVVEF 256
Query: 164 YCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENF 222
C+ + + G +C +W LP C + + P P+ A ++ N E F
Sbjct: 257 RCQPGFGMKGPSHVKCQALNKWEPELPSCSRVCQ-PPPDVLHAERTQRDKDNFSPGQEVF 315
Score = 38.1 bits (87), Expect = 0.007
Identities = 30/138 (21%), Positives = 56/138 (40%), Gaps = 17/138 (12%)
Query: 15 VSASDAEHCPELP-PVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNAS---KEWD 70
V + + C P PV+ + V ++ Y C G+ L+G + C S W
Sbjct: 405 VPVCERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSGNTAHWS 464
Query: 71 NTTTECRLGHCPD-PVLVNGEFSSS--GPVNVSDKITFMCNDH-------YILKGSNRSQ 120
C+ CP+ P ++NG + + G + ++++ C+ H ++ S +
Sbjct: 465 MKPPICQQIFCPNPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLIGESTIRR 524
Query: 121 CLEDH---TWAPPFPICK 135
E H W+ P P C+
Sbjct: 525 TSEPHGNGVWSSPAPRCE 542
>gi|166235138 seizure related 6 homolog (mouse)-like 2 isoform 3
[Homo sapiens]
Length = 840
Score = 77.8 bits (190), Expect = 8e-15
Identities = 60/204 (29%), Positives = 89/204 (43%), Gaps = 19/204 (9%)
Query: 23 CPELPPVDNSIFVAKE---VEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTEC-RL 78
CPELPP + A + G +L TY C GY L+G L C W C ++
Sbjct: 574 CPELPPPEWGWRTASHGDLIRGTVL-TYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 632
Query: 79 GHCPDP-VLVNG-EFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHT----WAPPFP 132
C DP + NG +S V + + C Y L+G+ C T W+ P
Sbjct: 633 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 692
Query: 133 IC--KSRDCDPPGNPVHGY--FEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWS 185
C K C PG P +GY +++ G ++ ++C + + L+G CV G +W+
Sbjct: 693 KCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWT 752
Query: 186 SALPVCKLIQEA-PKPECEKALLA 208
S P+CK+ Q P + E LA
Sbjct: 753 SQPPLCKVTQTTDPSRQLEGGNLA 776
Score = 35.0 bits (79), Expect = 0.062
Identities = 16/56 (28%), Positives = 25/56 (44%), Gaps = 3/56 (5%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVC 191
C P P HG + G T +++C+ Y L G + C++G W+ P C
Sbjct: 220 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 275
Score = 28.1 bits (61), Expect = 7.6
Identities = 12/33 (36%), Positives = 16/33 (48%), Gaps = 2/33 (6%)
Query: 46 TYVCIKGYHLVGKKTLFC--NASKEWDNTTTEC 76
T+ C GY L G++TL C W+ T C
Sbjct: 243 TFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 275
>gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2
[Homo sapiens]
Length = 910
Score = 77.8 bits (190), Expect = 8e-15
Identities = 60/204 (29%), Positives = 89/204 (43%), Gaps = 19/204 (9%)
Query: 23 CPELPPVDNSIFVAKE---VEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTEC-RL 78
CPELPP + A + G +L TY C GY L+G L C W C ++
Sbjct: 644 CPELPPPEWGWRTASHGDLIRGTVL-TYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 702
Query: 79 GHCPDP-VLVNG-EFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHT----WAPPFP 132
C DP + NG +S V + + C Y L+G+ C T W+ P
Sbjct: 703 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 762
Query: 133 IC--KSRDCDPPGNPVHGY--FEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWS 185
C K C PG P +GY +++ G ++ ++C + + L+G CV G +W+
Sbjct: 763 KCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWT 822
Query: 186 SALPVCKLIQEA-PKPECEKALLA 208
S P+CK+ Q P + E LA
Sbjct: 823 SQPPLCKVTQTTDPSRQLEGGNLA 846
Score = 35.0 bits (79), Expect = 0.062
Identities = 16/56 (28%), Positives = 25/56 (44%), Gaps = 3/56 (5%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVC 191
C P P HG + G T +++C+ Y L G + C++G W+ P C
Sbjct: 290 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 345
Score = 28.1 bits (61), Expect = 7.6
Identities = 12/33 (36%), Positives = 16/33 (48%), Gaps = 2/33 (6%)
Query: 46 TYVCIKGYHLVGKKTLFC--NASKEWDNTTTEC 76
T+ C GY L G++TL C W+ T C
Sbjct: 313 TFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 345
>gi|86793109 complement receptor 1 isoform S precursor [Homo sapiens]
Length = 2489
Score = 77.4 bits (189), Expect = 1e-14
Identities = 53/189 (28%), Positives = 83/189 (43%), Gaps = 21/189 (11%)
Query: 23 CPELPPVDNSIFVAKEVEGQILG---TYVCIKG------YHLVGKKTLFCNASKE----W 69
C P + N F++ E G TY C G + LVG+ +++C ++ + W
Sbjct: 1516 CGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIW 1575
Query: 70 DNTTTECRLGH-CPDPVLVNGEFSSSGP--VNVSDKITFMCNDHYILKGSNRSQCLEDHT 126
+C + + C P + NG S ++++ + F C +++KG R +C +
Sbjct: 1576 SGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK 1635
Query: 127 WAPPFPICKSRDCDPPGNPVHGYF---EGNNFTLGSTISYYCEDRYYLVGVQEQQCV-DG 182
W P P C SR C PP +HG +NF+ G + Y CE Y L G C G
Sbjct: 1636 WEPELPSC-SRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQG 1694
Query: 183 EWSSALPVC 191
+WS P C
Sbjct: 1695 DWSPEAPRC 1703
Score = 77.4 bits (189), Expect = 1e-14
Identities = 42/124 (33%), Positives = 56/124 (45%), Gaps = 6/124 (4%)
Query: 23 CPELPPVDNSIFVAKEVEGQILG---TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLG 79
CP P + N ++ V + G +Y+C GY LVGK +FC W C+
Sbjct: 2298 CPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEV 2357
Query: 80 HCPDPVLVNG---EFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKS 136
+C P+ +NG E + D +T C D Y L+GS SQC D W PP C S
Sbjct: 2358 NCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPLAKCTS 2417
Query: 137 RDCD 140
R D
Sbjct: 2418 RTHD 2421
Score = 72.8 bits (177), Expect = 3e-13
Identities = 48/175 (27%), Positives = 76/175 (43%), Gaps = 13/175 (7%)
Query: 28 PVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLV 87
P + S F E+ + C G+ +VG T+ C + W C P P ++
Sbjct: 2053 PGNRSFFTLTEII-----RFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQPPPEIL 2107
Query: 88 NGEFSSSGPVNVS--DKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP-PGN 144
+GE + S N S ++ + C Y L+G+ C W+P P C + CD G
Sbjct: 2108 HGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQ 2167
Query: 145 PVHG-YFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV----DGEWSSALPVCKLI 194
HG N LG+ +S+ C++ + L G CV W+S++PVC+ I
Sbjct: 2168 LPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQI 2222
Score = 72.4 bits (176), Expect = 4e-13
Identities = 55/206 (26%), Positives = 84/206 (40%), Gaps = 29/206 (14%)
Query: 11 VAWRVSASDAE--HCPELPPVDNSIFVAKE---VEGQILGTYVCIKG------YHLVGKK 59
V W A E C P + N F + + TY C G + LVG++
Sbjct: 1955 VTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGER 2014
Query: 60 TLFCNASKE----WDN------TTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCND 109
+++C + + W + +T +C + + V G S +++ I F C
Sbjct: 2015 SIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSF---FTLTEIIRFRCQP 2071
Query: 110 HYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHG---YFEGNNFTLGSTISYYCE 166
+++ GS+ QC + W P P C SR C PP +HG +NF+ G + Y CE
Sbjct: 2072 GFVMVGSHTVQCQTNGRWGPKLPHC-SRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCE 2130
Query: 167 DRYYLVGVQEQQCV-DGEWSSALPVC 191
Y L G C G+WS P C
Sbjct: 2131 PSYDLRGAASLHCTPQGDWSPEAPRC 2156
Score = 72.0 bits (175), Expect = 5e-13
Identities = 62/211 (29%), Positives = 86/211 (40%), Gaps = 27/211 (12%)
Query: 20 AEHC--PELPPVDNSIFVAKEVEGQILGT---YVCIKGYHLVGKK-TLFCNASKEWDNTT 73
A HC PE P + + E + GT Y C GY GK ++ C + W +
Sbjct: 1843 AGHCKTPEQFPFASPTIPINDFEFPV-GTSLNYECRPGYF--GKMFSISCLENLVWSSVE 1899
Query: 74 TECRLGHC-PDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCL---EDHTWAP 129
CR C P P NG + + + CN+ + L GS + CL + TW
Sbjct: 1900 DNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDK 1959
Query: 130 PFPICKSRDCDPPGNPVHGYFEGNN---FTLGSTISYYC------EDRYYLVGVQEQQCV 180
PIC+ C+PP +G F NN F G+ ++Y C E + LVG + C
Sbjct: 1960 KAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCT 2019
Query: 181 D-----GEWSSALPVCKLIQEAPKPECEKAL 206
G WSS P C + PE E A+
Sbjct: 2020 SKDDQVGVWSSPPPRCISTNKCTAPEVENAI 2050
Score = 71.2 bits (173), Expect = 8e-13
Identities = 49/179 (27%), Positives = 79/179 (44%), Gaps = 11/179 (6%)
Query: 27 PPVDNSIFVAKEVEGQILGTYV---CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPD 83
P V+N I V+ L V C G+ + G + + C A +W+ C P
Sbjct: 1591 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP 1650
Query: 84 PVLVNGEFSSSGPVNVS--DKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 141
P +++GE + S N S ++ + C Y L+G+ C W+P P C + CD
Sbjct: 1651 PEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDD 1710
Query: 142 -PGNPVHG-YFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV----DGEWSSALPVCKLI 194
G HG N LG+ +S+ C++ + L G CV W++++PVC+ I
Sbjct: 1711 FLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHI 1769
Score = 70.9 bits (172), Expect = 1e-12
Identities = 47/174 (27%), Positives = 76/174 (43%), Gaps = 19/174 (10%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPV--LVNGEFSSSGPVNVSDKIT 104
Y C GY L G ++ C +W C + C D + L+NG + + K+
Sbjct: 324 YSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVD 383
Query: 105 FMCNDHYILKGSNRSQCL---EDHTWAPPFPICKSRDCDPPGNPVHGYFEGNN---FTLG 158
F+C++ + LKGS+ S C+ + W P+C+ C P +G G F G
Sbjct: 384 FVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFG 443
Query: 159 STISYYCE---DR---YYLVGVQEQQCV-----DGEWSSALPVCKLIQEAPKPE 201
T++Y C+ DR + L+G +C +G WSS P C ++ P+
Sbjct: 444 KTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPD 497
Score = 70.9 bits (172), Expect = 1e-12
Identities = 47/174 (27%), Positives = 76/174 (43%), Gaps = 19/174 (10%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPV--LVNGEFSSSGPVNVSDKIT 104
Y C GY L G ++ C +W C + C D + L+NG + + K+
Sbjct: 774 YSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVD 833
Query: 105 FMCNDHYILKGSNRSQCL---EDHTWAPPFPICKSRDCDPPGNPVHGYFEGNN---FTLG 158
F+C++ + LKGS+ S C+ + W P+C+ C P +G G F G
Sbjct: 834 FVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFG 893
Query: 159 STISYYCE---DR---YYLVGVQEQQCV-----DGEWSSALPVCKLIQEAPKPE 201
T++Y C+ DR + L+G +C +G WSS P C ++ P+
Sbjct: 894 KTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPD 947
Score = 69.3 bits (168), Expect = 3e-12
Identities = 46/179 (25%), Positives = 80/179 (44%), Gaps = 11/179 (6%)
Query: 27 PPVDNSIFVAKEVEGQILGTYV---CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPD 83
P V+N I V+ L V C G+ + G + + C A +W+ C P
Sbjct: 241 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP 300
Query: 84 PVLVNGEFSSSGPVNVS--DKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 141
P +++ E + N S ++ + C Y L+G+ +C W+P P C+ + CD
Sbjct: 301 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDD 360
Query: 142 -PGNPVHG-YFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV----DGEWSSALPVCKLI 194
G ++G N LG+ + + C++ + L G CV + W+S++PVC+ I
Sbjct: 361 FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 419
Score = 69.3 bits (168), Expect = 3e-12
Identities = 46/179 (25%), Positives = 80/179 (44%), Gaps = 11/179 (6%)
Query: 27 PPVDNSIFVAKEVEGQILGTYV---CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPD 83
P V+N I V+ L V C G+ + G + + C A +W+ C P
Sbjct: 691 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP 750
Query: 84 PVLVNGEFSSSGPVNVS--DKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 141
P +++ E + N S ++ + C Y L+G+ +C W+P P C+ + CD
Sbjct: 751 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDD 810
Query: 142 -PGNPVHG-YFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV----DGEWSSALPVCKLI 194
G ++G N LG+ + + C++ + L G CV + W+S++PVC+ I
Sbjct: 811 FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 869
Score = 69.3 bits (168), Expect = 3e-12
Identities = 46/179 (25%), Positives = 80/179 (44%), Gaps = 11/179 (6%)
Query: 27 PPVDNSIFVAKEVEGQILGTYV---CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPD 83
P V+N I V+ L V C G+ + G + + C A +W+ C P
Sbjct: 1141 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP 1200
Query: 84 PVLVNGEFSSSGPVNVS--DKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 141
P +++ E + N S ++ + C Y L+G+ +C W+P P C+ + CD
Sbjct: 1201 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDD 1260
Query: 142 -PGNPVHG-YFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV----DGEWSSALPVCKLI 194
G ++G N LG+ + + C++ + L G CV + W+S++PVC+ I
Sbjct: 1261 FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 1319
Score = 68.9 bits (167), Expect = 4e-12
Identities = 46/174 (26%), Positives = 75/174 (43%), Gaps = 19/174 (10%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPV--LVNGEFSSSGPVNVSDKIT 104
Y C GY L G ++ C +W C + C D + L+NG + + K+
Sbjct: 1224 YSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVD 1283
Query: 105 FMCNDHYILKGSNRSQCL---EDHTWAPPFPICKSRDCDPPGNPVHGYFEGNN---FTLG 158
F+C++ + LKGS+ S C+ + W P+C+ C P +G G F G
Sbjct: 1284 FVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFG 1343
Query: 159 STISYYCE---DR---YYLVGVQEQQCV-----DGEWSSALPVCKLIQEAPKPE 201
++Y C+ DR + L+G +C +G WSS P C ++ P+
Sbjct: 1344 KAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPD 1397
Score = 68.9 bits (167), Expect = 4e-12
Identities = 62/232 (26%), Positives = 92/232 (39%), Gaps = 47/232 (20%)
Query: 8 CLMVA----WRVSASDAEH--CPELPPVDNS---------IFVAKEVEGQILGTYVCIKG 52
C++V W S EH CP P + N I KE+ +Y C
Sbjct: 1750 CVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEI------SYTCDPH 1803
Query: 53 ------YHLVGKKTLFCNASKE----WDNTTTECRL----GHCPDPVLVNGEFSSSGPVN 98
++L+G+ T+ C + W + C L GHC P S + P+N
Sbjct: 1804 PDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFA-SPTIPIN 1862
Query: 99 -----VSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGN 153
V + + C Y K + S CLE+ W+ C+ + C PP P +G N
Sbjct: 1863 DFEFPVGTSLNYECRPGYFGKMFSIS-CLENLVWSSVEDNCRRKSCGPPPEPFNGMVHIN 1921
Query: 154 NFT-LGSTISYYCEDRYYLVGVQEQQC-VDGE---WSSALPVCKLIQEAPKP 200
T GST++Y C + + L+G C V G W P+C++I P P
Sbjct: 1922 TDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPP 1973
Score = 68.2 bits (165), Expect = 7e-12
Identities = 54/209 (25%), Positives = 86/209 (41%), Gaps = 30/209 (14%)
Query: 13 WRVSASDAEH--CPELPPVDNSIFVAKEVEGQILG---TYVCIK------GYHLVGKKTL 61
W S E CP P + N K +E G Y C + L+G+ T+
Sbjct: 1309 WNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTI 1368
Query: 62 FCNASKE----WDNTTTECR-LGHCPDP------VLVNGEFSSSGPVNVSDKITFMCNDH 110
C + + W + C LGHC P L +S P+ S K + C
Sbjct: 1369 RCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLK--YECRPE 1426
Query: 111 YILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEG-NNFTLGSTISYYCEDRY 169
Y + + + CL++ W+ P +CK + C P +PV+G + +GS I+Y C +
Sbjct: 1427 YYGRPFSIT-CLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGH 1485
Query: 170 YLVGVQEQQCV----DGEWSSALPVCKLI 194
L+G +C+ WS+ P+C+ I
Sbjct: 1486 RLIGHSSAECILSGNTAHWSTKPPICQRI 1514
Score = 67.8 bits (164), Expect = 9e-12
Identities = 54/209 (25%), Positives = 86/209 (41%), Gaps = 30/209 (14%)
Query: 13 WRVSASDAEH--CPELPPVDNSIFVAKEVEGQILG---TYVCIK------GYHLVGKKTL 61
W S E CP P + N K +E G Y C + L+G+ T+
Sbjct: 409 WNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTI 468
Query: 62 FCNASKE----WDNTTTECR-LGHCPDP------VLVNGEFSSSGPVNVSDKITFMCNDH 110
C + + W + C LGHC P L +S P+ S K + C
Sbjct: 469 RCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLK--YECRPE 526
Query: 111 YILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEG-NNFTLGSTISYYCEDRY 169
Y + + + CL++ W+ P +CK + C P +PV+G + +GS I+Y C +
Sbjct: 527 YYGRPFSIT-CLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGH 585
Query: 170 YLVGVQEQQCV----DGEWSSALPVCKLI 194
L+G +C+ WS+ P+C+ I
Sbjct: 586 RLIGHSSAECILSGNAAHWSTKPPICQRI 614
Score = 67.8 bits (164), Expect = 9e-12
Identities = 54/209 (25%), Positives = 86/209 (41%), Gaps = 30/209 (14%)
Query: 13 WRVSASDAEH--CPELPPVDNSIFVAKEVEGQILG---TYVCIK------GYHLVGKKTL 61
W S E CP P + N K +E G Y C + L+G+ T+
Sbjct: 859 WNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTI 918
Query: 62 FCNASKE----WDNTTTECR-LGHCPDP------VLVNGEFSSSGPVNVSDKITFMCNDH 110
C + + W + C LGHC P L +S P+ S K + C
Sbjct: 919 RCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLK--YECRPE 976
Query: 111 YILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEG-NNFTLGSTISYYCEDRY 169
Y + + + CL++ W+ P +CK + C P +PV+G + +GS I+Y C +
Sbjct: 977 YYGRPFSIT-CLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGH 1035
Query: 170 YLVGVQEQQCV----DGEWSSALPVCKLI 194
L+G +C+ WS+ P+C+ I
Sbjct: 1036 RLIGHSSAECILSGNAAHWSTKPPICQRI 1064
Score = 65.5 bits (158), Expect = 4e-11
Identities = 56/216 (25%), Positives = 87/216 (40%), Gaps = 23/216 (10%)
Query: 28 PVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKE---WDNTTTECRLGHCP-D 83
PV+ + V K ++ Y C KGY L+G + C S + WDN T C C
Sbjct: 110 PVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLP 169
Query: 84 PVLVNGEFSSSGPVN--VSDKITFMCNDH------YILKGSNRSQCLEDH----TWAPPF 131
P + NG+F S+ N +T+ CN + L G C + W+ P
Sbjct: 170 PTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPA 229
Query: 132 PIC-KSRDCDPPGNPVHGYFEGNN---FTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSS 186
P C C PP N +G +N F+L + + C+ + + G + +C +W
Sbjct: 230 PQCIIPNKCTPP-NVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 288
Query: 187 ALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENF 222
LP C + + P P+ A ++ N E F
Sbjct: 289 ELPSCSRVCQ-PPPDVLHAERTQRDKDNFSPGQEVF 323
Score = 65.1 bits (157), Expect = 6e-11
Identities = 49/177 (27%), Positives = 74/177 (41%), Gaps = 19/177 (10%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPV--LVNGEFSSSGPVNVSDKIT 104
Y C Y L G +L C +W C + C D + L +G + + K++
Sbjct: 2127 YSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVS 2186
Query: 105 FMCNDHYILKGSNRSQCL---EDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNF---TLG 158
F+C++ + LKG + S C+ W P+C+ C P ++G G F G
Sbjct: 2187 FVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYG 2246
Query: 159 STISYYCE---DR---YYLVGVQEQQCV-----DGEWSSALPVCKLIQEAPKPECEK 204
ISY C+ DR + L+G +C +G WSS P C+L A P K
Sbjct: 2247 KEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPK 2303
Score = 58.5 bits (140), Expect = 5e-09
Identities = 57/210 (27%), Positives = 78/210 (37%), Gaps = 29/210 (13%)
Query: 22 HCPELPPVDNSIFVAKEVEGQILGTYV---CIKGYHLVGKK-TLFCNASKEWDNTTTECR 77
+ PE P + E E I GTY+ C GY G+ ++ C + W CR
Sbjct: 44 NAPEWLPFARPTNLTDEFEFPI-GTYLNYECRPGYS--GRPFSIICLKNSVWTGAKDRCR 100
Query: 78 LGHC---PDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCL---EDHTWAPPF 131
C PDPV NG + +I + C Y L GS+ + C+ + W
Sbjct: 101 RKSCRNPPDPV--NGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNET 158
Query: 132 PICKSRDCDPPGNPVHGYF---EGNNFTLGSTISYYCEDR------YYLVGVQEQQCVD- 181
PIC C P +G F NF GS ++Y C + LVG C
Sbjct: 159 PICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSN 218
Query: 182 ----GEWSSALPVCKLIQEAPKPECEKALL 207
G WS P C + + P E +L
Sbjct: 219 DDQVGIWSGPAPQCIIPNKCTPPNVENGIL 248
Score = 53.1 bits (126), Expect = 2e-07
Identities = 42/168 (25%), Positives = 64/168 (38%), Gaps = 22/168 (13%)
Query: 60 TLFCNASKEWDNTTTECRLGHC---PDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGS 116
++ C + W + C+ C PDPV NG + V +I + C + L G
Sbjct: 533 SITCLDNLVWSSPKDVCKRKSCKTPPDPV--NGMVHVITDIQVGSRINYSCTTGHRLIGH 590
Query: 117 NRSQCLEDHT---WAPPFPICKSRDCDPPGNPVHGYF---EGNNFTLGSTISYYCEDR-- 168
+ ++C+ W+ PIC+ C P +G F NF GS ++Y C
Sbjct: 591 SSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSG 650
Query: 169 ----YYLVGVQEQQCVD-----GEWSSALPVCKLIQEAPKPECEKALL 207
+ LVG C G WS P C + + P E +L
Sbjct: 651 GRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGIL 698
Score = 53.1 bits (126), Expect = 2e-07
Identities = 42/168 (25%), Positives = 64/168 (38%), Gaps = 22/168 (13%)
Query: 60 TLFCNASKEWDNTTTECRLGHC---PDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGS 116
++ C + W + C+ C PDPV NG + V +I + C + L G
Sbjct: 983 SITCLDNLVWSSPKDVCKRKSCKTPPDPV--NGMVHVITDIQVGSRINYSCTTGHRLIGH 1040
Query: 117 NRSQCLEDHT---WAPPFPICKSRDCDPPGNPVHGYF---EGNNFTLGSTISYYCEDR-- 168
+ ++C+ W+ PIC+ C P +G F NF GS ++Y C
Sbjct: 1041 SSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSG 1100
Query: 169 ----YYLVGVQEQQCVD-----GEWSSALPVCKLIQEAPKPECEKALL 207
+ LVG C G WS P C + + P E +L
Sbjct: 1101 GRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGIL 1148
Score = 53.1 bits (126), Expect = 2e-07
Identities = 44/168 (26%), Positives = 66/168 (39%), Gaps = 22/168 (13%)
Query: 60 TLFCNASKEWDNTTTECRLGHC---PDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGS 116
++ C + W + C+ C PDPV NG + V +I + C + L G
Sbjct: 1433 SITCLDNLVWSSPKDVCKRKSCKTPPDPV--NGMVHVITDIQVGSRINYSCTTGHRLIGH 1490
Query: 117 NRSQC-LEDHT--WAPPFPICKSRDCDPPGNPVHGYF---EGNNFTLGSTISYYC----- 165
+ ++C L +T W+ PIC+ C P +G F NF GS ++Y C
Sbjct: 1491 SSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSR 1550
Query: 166 -EDRYYLVGVQEQQCVD-----GEWSSALPVCKLIQEAPKPECEKALL 207
+ LVG C G WS P C + + P E +L
Sbjct: 1551 GRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGIL 1598
Score = 49.7 bits (117), Expect = 2e-06
Identities = 37/153 (24%), Positives = 61/153 (39%), Gaps = 14/153 (9%)
Query: 53 YHLVGKKTLFCNASKE----WDNTTTECRLG---HCPDPVLVNGEFSSSGPVNV---SDK 102
++L+G+ ++ C + + W + C L CP P + G V++
Sbjct: 2263 FNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMT 2322
Query: 103 ITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPP--GNPVHGYFEGNN-FTLGS 159
I+++C+ Y+L G C + W+ CK +C P N + E + G
Sbjct: 2323 ISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGD 2382
Query: 160 TISYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 191
++ CED Y L G QC D W L C
Sbjct: 2383 YVTLKCEDGYTLEGSPWSQCQADDRWDPPLAKC 2415
>gi|86793036 complement receptor 1 isoform F precursor [Homo sapiens]
Length = 2039
Score = 77.4 bits (189), Expect = 1e-14
Identities = 53/189 (28%), Positives = 83/189 (43%), Gaps = 21/189 (11%)
Query: 23 CPELPPVDNSIFVAKEVEGQILG---TYVCIKG------YHLVGKKTLFCNASKE----W 69
C P + N F++ E G TY C G + LVG+ +++C ++ + W
Sbjct: 1066 CGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIW 1125
Query: 70 DNTTTECRLGH-CPDPVLVNGEFSSSGP--VNVSDKITFMCNDHYILKGSNRSQCLEDHT 126
+C + + C P + NG S ++++ + F C +++KG R +C +
Sbjct: 1126 SGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK 1185
Query: 127 WAPPFPICKSRDCDPPGNPVHGYF---EGNNFTLGSTISYYCEDRYYLVGVQEQQCV-DG 182
W P P C SR C PP +HG +NF+ G + Y CE Y L G C G
Sbjct: 1186 WEPELPSC-SRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQG 1244
Query: 183 EWSSALPVC 191
+WS P C
Sbjct: 1245 DWSPEAPRC 1253
Score = 77.4 bits (189), Expect = 1e-14
Identities = 42/124 (33%), Positives = 56/124 (45%), Gaps = 6/124 (4%)
Query: 23 CPELPPVDNSIFVAKEVEGQILG---TYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLG 79
CP P + N ++ V + G +Y+C GY LVGK +FC W C+
Sbjct: 1848 CPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEV 1907
Query: 80 HCPDPVLVNG---EFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKS 136
+C P+ +NG E + D +T C D Y L+GS SQC D W PP C S
Sbjct: 1908 NCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPLAKCTS 1967
Query: 137 RDCD 140
R D
Sbjct: 1968 RTHD 1971
Score = 72.8 bits (177), Expect = 3e-13
Identities = 48/175 (27%), Positives = 76/175 (43%), Gaps = 13/175 (7%)
Query: 28 PVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLV 87
P + S F E+ + C G+ +VG T+ C + W C P P ++
Sbjct: 1603 PGNRSFFTLTEII-----RFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQPPPEIL 1657
Query: 88 NGEFSSSGPVNVS--DKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP-PGN 144
+GE + S N S ++ + C Y L+G+ C W+P P C + CD G
Sbjct: 1658 HGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQ 1717
Query: 145 PVHG-YFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV----DGEWSSALPVCKLI 194
HG N LG+ +S+ C++ + L G CV W+S++PVC+ I
Sbjct: 1718 LPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQI 1772
Score = 72.4 bits (176), Expect = 4e-13
Identities = 55/206 (26%), Positives = 84/206 (40%), Gaps = 29/206 (14%)
Query: 11 VAWRVSASDAE--HCPELPPVDNSIFVAKE---VEGQILGTYVCIKG------YHLVGKK 59
V W A E C P + N F + + TY C G + LVG++
Sbjct: 1505 VTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGER 1564
Query: 60 TLFCNASKE----WDN------TTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCND 109
+++C + + W + +T +C + + V G S +++ I F C
Sbjct: 1565 SIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSF---FTLTEIIRFRCQP 1621
Query: 110 HYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHG---YFEGNNFTLGSTISYYCE 166
+++ GS+ QC + W P P C SR C PP +HG +NF+ G + Y CE
Sbjct: 1622 GFVMVGSHTVQCQTNGRWGPKLPHC-SRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCE 1680
Query: 167 DRYYLVGVQEQQCV-DGEWSSALPVC 191
Y L G C G+WS P C
Sbjct: 1681 PSYDLRGAASLHCTPQGDWSPEAPRC 1706
Score = 72.0 bits (175), Expect = 5e-13
Identities = 62/211 (29%), Positives = 86/211 (40%), Gaps = 27/211 (12%)
Query: 20 AEHC--PELPPVDNSIFVAKEVEGQILGT---YVCIKGYHLVGKK-TLFCNASKEWDNTT 73
A HC PE P + + E + GT Y C GY GK ++ C + W +
Sbjct: 1393 AGHCKTPEQFPFASPTIPINDFEFPV-GTSLNYECRPGYF--GKMFSISCLENLVWSSVE 1449
Query: 74 TECRLGHC-PDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCL---EDHTWAP 129
CR C P P NG + + + CN+ + L GS + CL + TW
Sbjct: 1450 DNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDK 1509
Query: 130 PFPICKSRDCDPPGNPVHGYFEGNN---FTLGSTISYYC------EDRYYLVGVQEQQCV 180
PIC+ C+PP +G F NN F G+ ++Y C E + LVG + C
Sbjct: 1510 KAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCT 1569
Query: 181 D-----GEWSSALPVCKLIQEAPKPECEKAL 206
G WSS P C + PE E A+
Sbjct: 1570 SKDDQVGVWSSPPPRCISTNKCTAPEVENAI 1600
Score = 71.2 bits (173), Expect = 8e-13
Identities = 49/179 (27%), Positives = 79/179 (44%), Gaps = 11/179 (6%)
Query: 27 PPVDNSIFVAKEVEGQILGTYV---CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPD 83
P V+N I V+ L V C G+ + G + + C A +W+ C P
Sbjct: 1141 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP 1200
Query: 84 PVLVNGEFSSSGPVNVS--DKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 141
P +++GE + S N S ++ + C Y L+G+ C W+P P C + CD
Sbjct: 1201 PEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDD 1260
Query: 142 -PGNPVHG-YFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV----DGEWSSALPVCKLI 194
G HG N LG+ +S+ C++ + L G CV W++++PVC+ I
Sbjct: 1261 FLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHI 1319
Score = 70.9 bits (172), Expect = 1e-12
Identities = 47/174 (27%), Positives = 76/174 (43%), Gaps = 19/174 (10%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPV--LVNGEFSSSGPVNVSDKIT 104
Y C GY L G ++ C +W C + C D + L+NG + + K+
Sbjct: 324 YSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVD 383
Query: 105 FMCNDHYILKGSNRSQCL---EDHTWAPPFPICKSRDCDPPGNPVHGYFEGNN---FTLG 158
F+C++ + LKGS+ S C+ + W P+C+ C P +G G F G
Sbjct: 384 FVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFG 443
Query: 159 STISYYCE---DR---YYLVGVQEQQCV-----DGEWSSALPVCKLIQEAPKPE 201
T++Y C+ DR + L+G +C +G WSS P C ++ P+
Sbjct: 444 KTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPD 497
Score = 69.3 bits (168), Expect = 3e-12
Identities = 46/179 (25%), Positives = 80/179 (44%), Gaps = 11/179 (6%)
Query: 27 PPVDNSIFVAKEVEGQILGTYV---CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPD 83
P V+N I V+ L V C G+ + G + + C A +W+ C P
Sbjct: 241 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP 300
Query: 84 PVLVNGEFSSSGPVNVS--DKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 141
P +++ E + N S ++ + C Y L+G+ +C W+P P C+ + CD
Sbjct: 301 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDD 360
Query: 142 -PGNPVHG-YFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV----DGEWSSALPVCKLI 194
G ++G N LG+ + + C++ + L G CV + W+S++PVC+ I
Sbjct: 361 FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 419
Score = 69.3 bits (168), Expect = 3e-12
Identities = 46/179 (25%), Positives = 80/179 (44%), Gaps = 11/179 (6%)
Query: 27 PPVDNSIFVAKEVEGQILGTYV---CIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPD 83
P V+N I V+ L V C G+ + G + + C A +W+ C P
Sbjct: 691 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP 750
Query: 84 PVLVNGEFSSSGPVNVS--DKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 141
P +++ E + N S ++ + C Y L+G+ +C W+P P C+ + CD
Sbjct: 751 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDD 810
Query: 142 -PGNPVHG-YFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV----DGEWSSALPVCKLI 194
G ++G N LG+ + + C++ + L G CV + W+S++PVC+ I
Sbjct: 811 FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 869
Score = 68.9 bits (167), Expect = 4e-12
Identities = 46/174 (26%), Positives = 75/174 (43%), Gaps = 19/174 (10%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPV--LVNGEFSSSGPVNVSDKIT 104
Y C GY L G ++ C +W C + C D + L+NG + + K+
Sbjct: 774 YSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVD 833
Query: 105 FMCNDHYILKGSNRSQCL---EDHTWAPPFPICKSRDCDPPGNPVHGYFEGNN---FTLG 158
F+C++ + LKGS+ S C+ + W P+C+ C P +G G F G
Sbjct: 834 FVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFG 893
Query: 159 STISYYCE---DR---YYLVGVQEQQCV-----DGEWSSALPVCKLIQEAPKPE 201
++Y C+ DR + L+G +C +G WSS P C ++ P+
Sbjct: 894 KAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPD 947
Score = 68.9 bits (167), Expect = 4e-12
Identities = 62/232 (26%), Positives = 92/232 (39%), Gaps = 47/232 (20%)
Query: 8 CLMVA----WRVSASDAEH--CPELPPVDNS---------IFVAKEVEGQILGTYVCIKG 52
C++V W S EH CP P + N I KE+ +Y C
Sbjct: 1300 CVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEI------SYTCDPH 1353
Query: 53 ------YHLVGKKTLFCNASKE----WDNTTTECRL----GHCPDPVLVNGEFSSSGPVN 98
++L+G+ T+ C + W + C L GHC P S + P+N
Sbjct: 1354 PDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFA-SPTIPIN 1412
Query: 99 -----VSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGN 153
V + + C Y K + S CLE+ W+ C+ + C PP P +G N
Sbjct: 1413 DFEFPVGTSLNYECRPGYFGKMFSIS-CLENLVWSSVEDNCRRKSCGPPPEPFNGMVHIN 1471
Query: 154 NFT-LGSTISYYCEDRYYLVGVQEQQC-VDGE---WSSALPVCKLIQEAPKP 200
T GST++Y C + + L+G C V G W P+C++I P P
Sbjct: 1472 TDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPP 1523
Score = 68.2 bits (165), Expect = 7e-12
Identities = 54/209 (25%), Positives = 86/209 (41%), Gaps = 30/209 (14%)
Query: 13 WRVSASDAEH--CPELPPVDNSIFVAKEVEGQILG---TYVCIK------GYHLVGKKTL 61
W S E CP P + N K +E G Y C + L+G+ T+
Sbjct: 859 WNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTI 918
Query: 62 FCNASKE----WDNTTTECR-LGHCPDP------VLVNGEFSSSGPVNVSDKITFMCNDH 110
C + + W + C LGHC P L +S P+ S K + C
Sbjct: 919 RCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLK--YECRPE 976
Query: 111 YILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEG-NNFTLGSTISYYCEDRY 169
Y + + + CL++ W+ P +CK + C P +PV+G + +GS I+Y C +
Sbjct: 977 YYGRPFSIT-CLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGH 1035
Query: 170 YLVGVQEQQCV----DGEWSSALPVCKLI 194
L+G +C+ WS+ P+C+ I
Sbjct: 1036 RLIGHSSAECILSGNTAHWSTKPPICQRI 1064
Score = 67.8 bits (164), Expect = 9e-12
Identities = 54/209 (25%), Positives = 86/209 (41%), Gaps = 30/209 (14%)
Query: 13 WRVSASDAEH--CPELPPVDNSIFVAKEVEGQILG---TYVCIK------GYHLVGKKTL 61
W S E CP P + N K +E G Y C + L+G+ T+
Sbjct: 409 WNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTI 468
Query: 62 FCNASKE----WDNTTTECR-LGHCPDP------VLVNGEFSSSGPVNVSDKITFMCNDH 110
C + + W + C LGHC P L +S P+ S K + C
Sbjct: 469 RCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLK--YECRPE 526
Query: 111 YILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEG-NNFTLGSTISYYCEDRY 169
Y + + + CL++ W+ P +CK + C P +PV+G + +GS I+Y C +
Sbjct: 527 YYGRPFSIT-CLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGH 585
Query: 170 YLVGVQEQQCV----DGEWSSALPVCKLI 194
L+G +C+ WS+ P+C+ I
Sbjct: 586 RLIGHSSAECILSGNAAHWSTKPPICQRI 614
Score = 65.5 bits (158), Expect = 4e-11
Identities = 56/216 (25%), Positives = 87/216 (40%), Gaps = 23/216 (10%)
Query: 28 PVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKE---WDNTTTECRLGHCP-D 83
PV+ + V K ++ Y C KGY L+G + C S + WDN T C C
Sbjct: 110 PVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLP 169
Query: 84 PVLVNGEFSSSGPVN--VSDKITFMCNDH------YILKGSNRSQCLEDH----TWAPPF 131
P + NG+F S+ N +T+ CN + L G C + W+ P
Sbjct: 170 PTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPA 229
Query: 132 PIC-KSRDCDPPGNPVHGYFEGNN---FTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSS 186
P C C PP N +G +N F+L + + C+ + + G + +C +W
Sbjct: 230 PQCIIPNKCTPP-NVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 288
Query: 187 ALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENF 222
LP C + + P P+ A ++ N E F
Sbjct: 289 ELPSCSRVCQ-PPPDVLHAERTQRDKDNFSPGQEVF 323
Score = 65.1 bits (157), Expect = 6e-11
Identities = 49/177 (27%), Positives = 74/177 (41%), Gaps = 19/177 (10%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPV--LVNGEFSSSGPVNVSDKIT 104
Y C Y L G +L C +W C + C D + L +G + + K++
Sbjct: 1677 YSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVS 1736
Query: 105 FMCNDHYILKGSNRSQCL---EDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNF---TLG 158
F+C++ + LKG + S C+ W P+C+ C P ++G G F G
Sbjct: 1737 FVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYG 1796
Query: 159 STISYYCE---DR---YYLVGVQEQQCV-----DGEWSSALPVCKLIQEAPKPECEK 204
ISY C+ DR + L+G +C +G WSS P C+L A P K
Sbjct: 1797 KEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPK 1853
Score = 58.5 bits (140), Expect = 5e-09
Identities = 57/210 (27%), Positives = 78/210 (37%), Gaps = 29/210 (13%)
Query: 22 HCPELPPVDNSIFVAKEVEGQILGTYV---CIKGYHLVGKK-TLFCNASKEWDNTTTECR 77
+ PE P + E E I GTY+ C GY G+ ++ C + W CR
Sbjct: 44 NAPEWLPFARPTNLTDEFEFPI-GTYLNYECRPGYS--GRPFSIICLKNSVWTGAKDRCR 100
Query: 78 LGHC---PDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCL---EDHTWAPPF 131
C PDPV NG + +I + C Y L GS+ + C+ + W
Sbjct: 101 RKSCRNPPDPV--NGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNET 158
Query: 132 PICKSRDCDPPGNPVHGYF---EGNNFTLGSTISYYCEDR------YYLVGVQEQQCVD- 181
PIC C P +G F NF GS ++Y C + LVG C
Sbjct: 159 PICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSN 218
Query: 182 ----GEWSSALPVCKLIQEAPKPECEKALL 207
G WS P C + + P E +L
Sbjct: 219 DDQVGIWSGPAPQCIIPNKCTPPNVENGIL 248
Score = 53.1 bits (126), Expect = 2e-07
Identities = 42/168 (25%), Positives = 64/168 (38%), Gaps = 22/168 (13%)
Query: 60 TLFCNASKEWDNTTTECRLGHC---PDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGS 116
++ C + W + C+ C PDPV NG + V +I + C + L G
Sbjct: 533 SITCLDNLVWSSPKDVCKRKSCKTPPDPV--NGMVHVITDIQVGSRINYSCTTGHRLIGH 590
Query: 117 NRSQCLEDHT---WAPPFPICKSRDCDPPGNPVHGYF---EGNNFTLGSTISYYCEDR-- 168
+ ++C+ W+ PIC+ C P +G F NF GS ++Y C
Sbjct: 591 SSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSG 650
Query: 169 ----YYLVGVQEQQCVD-----GEWSSALPVCKLIQEAPKPECEKALL 207
+ LVG C G WS P C + + P E +L
Sbjct: 651 GRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGIL 698
Score = 53.1 bits (126), Expect = 2e-07
Identities = 44/168 (26%), Positives = 66/168 (39%), Gaps = 22/168 (13%)
Query: 60 TLFCNASKEWDNTTTECRLGHC---PDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGS 116
++ C + W + C+ C PDPV NG + V +I + C + L G
Sbjct: 983 SITCLDNLVWSSPKDVCKRKSCKTPPDPV--NGMVHVITDIQVGSRINYSCTTGHRLIGH 1040
Query: 117 NRSQC-LEDHT--WAPPFPICKSRDCDPPGNPVHGYF---EGNNFTLGSTISYYC----- 165
+ ++C L +T W+ PIC+ C P +G F NF GS ++Y C
Sbjct: 1041 SSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSR 1100
Query: 166 -EDRYYLVGVQEQQCVD-----GEWSSALPVCKLIQEAPKPECEKALL 207
+ LVG C G WS P C + + P E +L
Sbjct: 1101 GRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGIL 1148
Score = 49.7 bits (117), Expect = 2e-06
Identities = 37/153 (24%), Positives = 61/153 (39%), Gaps = 14/153 (9%)
Query: 53 YHLVGKKTLFCNASKE----WDNTTTECRLG---HCPDPVLVNGEFSSSGPVNV---SDK 102
++L+G+ ++ C + + W + C L CP P + G V++
Sbjct: 1813 FNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMT 1872
Query: 103 ITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPP--GNPVHGYFEGNN-FTLGS 159
I+++C+ Y+L G C + W+ CK +C P N + E + G
Sbjct: 1873 ISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGD 1932
Query: 160 TISYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 191
++ CED Y L G QC D W L C
Sbjct: 1933 YVTLKCEDGYTLEGSPWSQCQADDRWDPPLAKC 1965
>gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4
[Homo sapiens]
Length = 809
Score = 77.0 bits (188), Expect = 1e-14
Identities = 56/191 (29%), Positives = 84/191 (43%), Gaps = 18/191 (9%)
Query: 23 CPELPPVDNSIFVAKE---VEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTEC-RL 78
CPELPP + A + G +L TY C GY L+G L C W C ++
Sbjct: 530 CPELPPPEWGWRTASHGDLIRGTVL-TYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 588
Query: 79 GHCPDP-VLVNG-EFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHT----WAPPFP 132
C DP + NG +S V + + C Y L+G+ C T W+ P
Sbjct: 589 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 648
Query: 133 IC--KSRDCDPPGNPVHGY--FEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWS 185
C K C PG P +GY +++ G ++ ++C + + L+G CV G +W+
Sbjct: 649 KCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWT 708
Query: 186 SALPVCKLIQE 196
S P+CK+ E
Sbjct: 709 SQPPLCKVAYE 719
Score = 35.0 bits (79), Expect = 0.062
Identities = 16/56 (28%), Positives = 25/56 (44%), Gaps = 3/56 (5%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVC 191
C P P HG + G T +++C+ Y L G + C++G W+ P C
Sbjct: 176 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 231
Score = 32.3 bits (72), Expect = 0.40
Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 158 GSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVCKLIQEAPKP 200
G+ ++Y CE Y L+G C D WS+A P C+ I P
Sbjct: 551 GTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADP 594
Score = 28.1 bits (61), Expect = 7.6
Identities = 12/33 (36%), Positives = 16/33 (48%), Gaps = 2/33 (6%)
Query: 46 TYVCIKGYHLVGKKTLFC--NASKEWDNTTTEC 76
T+ C GY L G++TL C W+ T C
Sbjct: 199 TFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 231
>gi|6912612 seizure related 6 homolog (mouse)-like 2 isoform 1 [Homo
sapiens]
Length = 853
Score = 77.0 bits (188), Expect = 1e-14
Identities = 56/191 (29%), Positives = 84/191 (43%), Gaps = 18/191 (9%)
Query: 23 CPELPPVDNSIFVAKE---VEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTEC-RL 78
CPELPP + A + G +L TY C GY L+G L C W C ++
Sbjct: 574 CPELPPPEWGWRTASHGDLIRGTVL-TYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 632
Query: 79 GHCPDP-VLVNG-EFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHT----WAPPFP 132
C DP + NG +S V + + C Y L+G+ C T W+ P
Sbjct: 633 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 692
Query: 133 IC--KSRDCDPPGNPVHGY--FEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWS 185
C K C PG P +GY +++ G ++ ++C + + L+G CV G +W+
Sbjct: 693 KCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWT 752
Query: 186 SALPVCKLIQE 196
S P+CK+ E
Sbjct: 753 SQPPLCKVAYE 763
Score = 35.0 bits (79), Expect = 0.062
Identities = 16/56 (28%), Positives = 25/56 (44%), Gaps = 3/56 (5%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EWSSALPVC 191
C P P HG + G T +++C+ Y L G + C++G W+ P C
Sbjct: 220 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 275
Score = 32.3 bits (72), Expect = 0.40
Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 158 GSTISYYCEDRYYLVGVQEQQCV-DGEWSSALPVCKLIQEAPKP 200
G+ ++Y CE Y L+G C D WS+A P C+ I P
Sbjct: 595 GTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADP 638
Score = 28.1 bits (61), Expect = 7.6
Identities = 12/33 (36%), Positives = 16/33 (48%), Gaps = 2/33 (6%)
Query: 46 TYVCIKGYHLVGKKTLFC--NASKEWDNTTTEC 76
T+ C GY L G++TL C W+ T C
Sbjct: 243 TFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 275
>gi|14550407 complement component 2 isoform 1 preproprotein [Homo
sapiens]
Length = 752
Score = 73.2 bits (178), Expect = 2e-13
Identities = 64/236 (27%), Positives = 92/236 (38%), Gaps = 18/236 (7%)
Query: 8 CLMVAWRVSASDAEHCPELPPVDNSIFVAKE--VEGQILGTYVCIKGYHLVGKKTLFCNA 65
CL+ + A A CP+ + F G +L TY C +G + L C +
Sbjct: 9 CLLFLYPGLADSAPSCPQNVNISGGTFTLSHGWAPGSLL-TYSCPQGLYPSPASRL-CKS 66
Query: 66 SKEWDN-------TTTECRLGHCPDPV-LVNGEFSSS-GPVNVSDKITFMCNDHYILKGS 116
S +W + C+ CP PV NG ++ G V ++F C D +IL+GS
Sbjct: 67 SGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGS 126
Query: 117 NRSQCLEDHTWAPPFPICKSR--DCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGV 174
QC + W +C + C PG + G F G + Y C L G
Sbjct: 127 PVRQCRPNGMWDGETAVCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGS 186
Query: 175 QEQQCV-DGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKES 229
E++C +G WS P+C+ PE L S L N Q+ KES
Sbjct: 187 SERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHML--GATNPTQKTKES 240
>gi|4502503 complement component 4 binding protein, alpha chain
precursor [Homo sapiens]
Length = 597
Score = 71.2 bits (173), Expect = 8e-13
Identities = 52/179 (29%), Positives = 82/179 (45%), Gaps = 14/179 (7%)
Query: 28 PVDNSIFVAKEVEGQILGTYVCIKGY-HLVGKKTLFCNASKEWDNTTTECRLGHCPDP-V 85
P+D ++ + G L Y C+ GY +TL CN+ EW T C C P
Sbjct: 61 PMDITLTETRFKTGTTL-KYTCLPGYVRSHSTQTLTCNSDGEWVYNTF-CIYKRCRHPGE 118
Query: 86 LVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQC-LEDH--TWAPPFPICKSRDCDPP 142
L NG+ ++ +I F C++ + L GS S+C ++D W+ P P C+ C PP
Sbjct: 119 LRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEIVKCKPP 178
Query: 143 GNPVHGYFEG--NNFTLGSTISYYCEDRYYLVGVQEQQC-----VDGEWSSALPVCKLI 194
+ +G G N + G +++Y C+ R+ L+G C G W + P C+ I
Sbjct: 179 PDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCEKI 237
Score = 62.8 bits (151), Expect = 3e-10
Identities = 53/202 (26%), Positives = 84/202 (41%), Gaps = 25/202 (12%)
Query: 17 ASDAEHCPELPPVDNSIFVA----KEVEGQILGT---YVCIKGYHLVGKK--TLFCNASK 67
A + C LP + ++ + + + ++GT Y C GY + T+ C +
Sbjct: 293 ACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNL 352
Query: 68 EWDNTTTECRLGHCPDPVLVNGEFSS---SGPVN-----VSDKITFMCNDHYILKGSNRS 119
W C CP+P L NGE + S P N D+I+F C++ +
Sbjct: 353 RW-TPYQGCEALCCPEPKLNNGEITQHRKSRPANHCVYFYGDEISFSCHE----TSRFSA 407
Query: 120 QCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFT--LGSTISYYCEDRYYLVGVQEQ 177
C D TW+P P C C+ P HG+++ ++ I Y C+ Y LVG +
Sbjct: 408 ICQGDGTWSPRTPSCGDI-CNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKL 466
Query: 178 QCVDGEWSSALPVCKLIQEAPK 199
C WS+ P CK + P+
Sbjct: 467 SCSYSHWSAPAPQCKALCRKPE 488
Score = 57.4 bits (137), Expect = 1e-08
Identities = 37/137 (27%), Positives = 57/137 (41%), Gaps = 13/137 (9%)
Query: 46 TYVCIKGYHLVGKKTLFCNASKE----WDNTTTECRLGHCPDPVLVNGEFSSS-GPV-NV 99
TY C + L+G ++ C E W + C C P + +GE S GP+ N
Sbjct: 200 TYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCEKITCRKPDVSHGEMVSGFGPIYNY 259
Query: 100 SDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFE-------G 152
D I F C ++L+GS+ C D W P P C+ C + H +E
Sbjct: 260 KDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKE 319
Query: 153 NNFTLGSTISYYCEDRY 169
+ + +G+ + Y C Y
Sbjct: 320 DVYVVGTVLRYRCHPGY 336
Score = 52.4 bits (124), Expect = 4e-07
Identities = 31/90 (34%), Positives = 41/90 (45%), Gaps = 3/90 (3%)
Query: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVS-DKITF 105
Y C KGY LVG+ L C+ S W +C+ C P LVNG S V + +T
Sbjct: 452 YECDKGYILVGQAKLSCSYS-HWSAPAPQCK-ALCRKPELVNGRLSVDKDQYVEPENVTI 509
Query: 106 MCNDHYILKGSNRSQCLEDHTWAPPFPICK 135
C+ Y + G C + TW P P C+
Sbjct: 510 QCDSGYGVVGPQSITCSGNRTWYPEVPKCE 539
Score = 43.1 bits (100), Expect = 2e-04
Identities = 34/140 (24%), Positives = 61/140 (43%), Gaps = 22/140 (15%)
Query: 78 LGHC-PDPVLVNGEFSSSGPVNVS---------DKITFMCNDHYILKGSNRS-QCLEDHT 126
LG+C P P L S + P++++ + + C Y+ S ++ C D
Sbjct: 47 LGNCGPPPTL-----SFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGE 101
Query: 127 WAPPFPICKSRDCDPPGNPVHGYFE-GNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE-- 183
W C + C PG +G E + + GS I + C + ++L+G +C +
Sbjct: 102 WVYN-TFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRG 160
Query: 184 --WSSALPVCKLIQEAPKPE 201
WS LP C++++ P P+
Sbjct: 161 VGWSHPLPQCEIVKCKPPPD 180
>gi|168693643 decay accelerating factor for complement isoform 2
precursor [Homo sapiens]
Length = 440
Score = 68.2 bits (165), Expect = 7e-12
Identities = 43/158 (27%), Positives = 67/158 (42%), Gaps = 12/158 (7%)
Query: 47 YVCIKGYHLVGKKT--LFCNASKEWDNTTTECRLGHCPDPVLV-NGEFSSSGPVNVSDKI 103
Y C GY + L C + +W C+ CP+P + NG+ G + I
Sbjct: 127 YECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATI 186
Query: 104 TFMCNDHYILKGSNRSQCL---EDHTWAPPFPICKSRDCDPPGNPVHGYFEG--NNFTLG 158
+F CN Y L GS S CL W+ P P C+ C P +G +G +++
Sbjct: 187 SFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYR 246
Query: 159 STISYYCEDRYYLVGVQEQQCV----DGEWSSALPVCK 192
+++Y C + ++G C +GEWS P C+
Sbjct: 247 QSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 54.3 bits (129), Expect = 1e-07
Identities = 45/214 (21%), Positives = 79/214 (36%), Gaps = 19/214 (8%)
Query: 8 CLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVG--KKTLFCNA 65
CL W D P++P ++ + TY C + + + K ++ C
Sbjct: 28 CLPAVW----GDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLK 83
Query: 66 SKEWDNTTTECRLGHCPDPVLVNGE-----FSSSGPVNVSDKITFMCNDHYILKGS--NR 118
+W + C C P +N + + V + + C Y + S +
Sbjct: 84 GSQWSDIEEFCNRS-CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPK 142
Query: 119 SQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFE-GNNFTLGSTISYYCEDRYYLVGVQEQ 177
CL++ W+ CK + C PG +G + G+TIS+ C Y L G
Sbjct: 143 LTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSS 202
Query: 178 QCVDG----EWSSALPVCKLIQEAPKPECEKALL 207
C+ +WS LP C+ I P+ + ++
Sbjct: 203 FCLISGSSVQWSDPLPECREIYCPAPPQIDNGII 236
Score = 38.9 bits (89), Expect = 0.004
Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 11/64 (17%)
Query: 22 HCPELPPVDNSIFVAKEVEGQILG-----TYVCIKGYHLVGKKTLFC---NASKEWDNTT 73
+CP P +DN I + E G TY C KG+ ++G+ +++C N EW
Sbjct: 224 YCPAPPQIDNGII---QGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPP 280
Query: 74 TECR 77
ECR
Sbjct: 281 PECR 284
>gi|10835143 decay accelerating factor for complement isoform 1
preproprotein [Homo sapiens]
Length = 381
Score = 68.2 bits (165), Expect = 7e-12
Identities = 43/158 (27%), Positives = 67/158 (42%), Gaps = 12/158 (7%)
Query: 47 YVCIKGYHLVGKKT--LFCNASKEWDNTTTECRLGHCPDPVLV-NGEFSSSGPVNVSDKI 103
Y C GY + L C + +W C+ CP+P + NG+ G + I
Sbjct: 127 YECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATI 186
Query: 104 TFMCNDHYILKGSNRSQCL---EDHTWAPPFPICKSRDCDPPGNPVHGYFEG--NNFTLG 158
+F CN Y L GS S CL W+ P P C+ C P +G +G +++
Sbjct: 187 SFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYR 246
Query: 159 STISYYCEDRYYLVGVQEQQCV----DGEWSSALPVCK 192
+++Y C + ++G C +GEWS P C+
Sbjct: 247 QSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 54.3 bits (129), Expect = 1e-07
Identities = 45/214 (21%), Positives = 79/214 (36%), Gaps = 19/214 (8%)
Query: 8 CLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVG--KKTLFCNA 65
CL W D P++P ++ + TY C + + + K ++ C
Sbjct: 28 CLPAVW----GDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLK 83
Query: 66 SKEWDNTTTECRLGHCPDPVLVNGE-----FSSSGPVNVSDKITFMCNDHYILKGS--NR 118
+W + C C P +N + + V + + C Y + S +
Sbjct: 84 GSQWSDIEEFCNRS-CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPK 142
Query: 119 SQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFE-GNNFTLGSTISYYCEDRYYLVGVQEQ 177
CL++ W+ CK + C PG +G + G+TIS+ C Y L G
Sbjct: 143 LTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSS 202
Query: 178 QCVDG----EWSSALPVCKLIQEAPKPECEKALL 207
C+ +WS LP C+ I P+ + ++
Sbjct: 203 FCLISGSSVQWSDPLPECREIYCPAPPQIDNGII 236
Score = 38.9 bits (89), Expect = 0.004
Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 11/64 (17%)
Query: 22 HCPELPPVDNSIFVAKEVEGQILG-----TYVCIKGYHLVGKKTLFC---NASKEWDNTT 73
+CP P +DN I + E G TY C KG+ ++G+ +++C N EW
Sbjct: 224 YCPAPPQIDNGII---QGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPP 280
Query: 74 TECR 77
ECR
Sbjct: 281 PECR 284
>gi|148839346 seizure related 6 homolog isoform 2 [Homo sapiens]
Length = 993
Score = 67.8 bits (164), Expect = 9e-12
Identities = 54/188 (28%), Positives = 78/188 (41%), Gaps = 19/188 (10%)
Query: 23 CPELPPVDN---SIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTEC-RL 78
CPELP + N S + V G ++ TY C GY +VG L C W C R+
Sbjct: 710 CPELPEIPNGWKSPSQPELVHGTVV-TYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRV 768
Query: 79 GHCPDP--VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHT----WAPPFP 132
C DP V + SS V + ++C+ ++L GS+ C + W+ P
Sbjct: 769 TSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAP 828
Query: 133 IC---KSRDCDPPGNPVHGYF--EGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EW 184
C + + C P +G E G+TI + C Y L G +CV G W
Sbjct: 829 KCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHW 888
Query: 185 SSALPVCK 192
S P+C+
Sbjct: 889 SDPPPICR 896
Score = 43.9 bits (102), Expect = 1e-04
Identities = 30/105 (28%), Positives = 45/105 (42%), Gaps = 11/105 (10%)
Query: 47 YVCIKGYHLVGKKTLFCN----ASKEWDNTTTECRLGHC-PDPVLVNGEFSSSGPVN--- 98
Y+C +G+ L+G L C+ S +W + +C L P L E + P
Sbjct: 797 YICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLH 856
Query: 99 -VSDKITFMCNDHYILKGSNRSQCLEDHT--WAPPFPICKSRDCD 140
I F C Y+LKG +C+ H W+ P PIC++ D
Sbjct: 857 PAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASLD 901
Score = 37.7 bits (86), Expect = 0.010
Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 4/62 (6%)
Query: 79 GHCPDPVLVNGEFSSSGPV-NVSDKITFMCNDHYIL-KGSNRSQCLEDH--TWAPPFPIC 134
GHC +P + G FSSS P V + F C+ Y L +GS +C++ H W P C
Sbjct: 530 GHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPAC 589
Query: 135 KS 136
++
Sbjct: 590 RA 591
Score = 30.0 bits (66), Expect = 2.0
Identities = 15/56 (26%), Positives = 23/56 (41%), Gaps = 3/56 (5%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE---WSSALPVC 191
C P P +G + G + ++C Y L G + C++ W S PVC
Sbjct: 357 CHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVC 412
>gi|148839280 seizure related 6 homolog isoform 1 [Homo sapiens]
Length = 994
Score = 67.8 bits (164), Expect = 9e-12
Identities = 54/188 (28%), Positives = 78/188 (41%), Gaps = 19/188 (10%)
Query: 23 CPELPPVDN---SIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTEC-RL 78
CPELP + N S + V G ++ TY C GY +VG L C W C R+
Sbjct: 710 CPELPEIPNGWKSPSQPELVHGTVV-TYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRV 768
Query: 79 GHCPDP--VLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHT----WAPPFP 132
C DP V + SS V + ++C+ ++L GS+ C + W+ P
Sbjct: 769 TSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAP 828
Query: 133 IC---KSRDCDPPGNPVHGYF--EGNNFTLGSTISYYCEDRYYLVGVQEQQCVDG---EW 184
C + + C P +G E G+TI + C Y L G +CV G W
Sbjct: 829 KCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHW 888
Query: 185 SSALPVCK 192
S P+C+
Sbjct: 889 SDPPPICR 896
Score = 43.9 bits (102), Expect = 1e-04
Identities = 30/105 (28%), Positives = 45/105 (42%), Gaps = 11/105 (10%)
Query: 47 YVCIKGYHLVGKKTLFCN----ASKEWDNTTTECRLGHC-PDPVLVNGEFSSSGPVN--- 98
Y+C +G+ L+G L C+ S +W + +C L P L E + P
Sbjct: 797 YICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLH 856
Query: 99 -VSDKITFMCNDHYILKGSNRSQCLEDHT--WAPPFPICKSRDCD 140
I F C Y+LKG +C+ H W+ P PIC++ D
Sbjct: 857 PAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASLD 901
Score = 37.7 bits (86), Expect = 0.010
Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 4/62 (6%)
Query: 79 GHCPDPVLVNGEFSSSGPV-NVSDKITFMCNDHYIL-KGSNRSQCLEDH--TWAPPFPIC 134
GHC +P + G FSSS P V + F C+ Y L +GS +C++ H W P C
Sbjct: 530 GHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPAC 589
Query: 135 KS 136
++
Sbjct: 590 RA 591
Score = 30.0 bits (66), Expect = 2.0
Identities = 15/56 (26%), Positives = 23/56 (41%), Gaps = 3/56 (5%)
Query: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGE---WSSALPVC 191
C P P +G + G + ++C Y L G + C++ W S PVC
Sbjct: 357 CHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVC 412
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.442
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,473,298
Number of Sequences: 37866
Number of extensions: 563261
Number of successful extensions: 2646
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 82
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 1502
Number of HSP's gapped (non-prelim): 586
length of query: 252
length of database: 18,247,518
effective HSP length: 100
effective length of query: 152
effective length of database: 14,460,918
effective search space: 2198059536
effective search space used: 2198059536
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.